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Network neighborhood for query Sequence : OSBP2_HUMAN

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OSBP2_HUMAN
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSBP1_HUMAN
θ value	0 (rank : 1)	NC score	0.974829 (rank : 3)
Query Neighborhood Hits	154	Target Neighborhood Hits	180	Shared Neighborhood Hits	69
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBP2_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	154
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
θ value	0 (rank : 3)	NC score	0.985261 (rank : 2)
Query Neighborhood Hits	154	Target Neighborhood Hits	150	Shared Neighborhood Hits	72
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL1_HUMAN
θ value	1.35324e-88 (rank : 4)	NC score	0.626779 (rank : 19)
Query Neighborhood Hits	154	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
θ value	1.49618e-87 (rank : 5)	NC score	0.641662 (rank : 18)
Query Neighborhood Hits	154	Target Neighborhood Hits	336	Shared Neighborhood Hits	33
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL3_MOUSE
θ value	2.09745e-73 (rank : 6)	NC score	0.893588 (rank : 7)
Query Neighborhood Hits	154	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_HUMAN
θ value	3.95564e-72 (rank : 7)	NC score	0.885711 (rank : 9)
Query Neighborhood Hits	154	Target Neighborhood Hits	101	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL2_MOUSE
θ value	1.15091e-71 (rank : 8)	NC score	0.904219 (rank : 4)
Query Neighborhood Hits	154	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL6_MOUSE
θ value	4.37348e-71 (rank : 9)	NC score	0.883123 (rank : 10)
Query Neighborhood Hits	154	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL2_HUMAN
θ value	5.71191e-71 (rank : 10)	NC score	0.904191 (rank : 5)
Query Neighborhood Hits	154	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL3_HUMAN
θ value	5.71191e-71 (rank : 11)	NC score	0.890017 (rank : 8)
Query Neighborhood Hits	154	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL7_HUMAN
θ value	8.53533e-67 (rank : 12)	NC score	0.900312 (rank : 6)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL5_HUMAN
θ value	1.09232e-21 (rank : 13)	NC score	0.692080 (rank : 12)
Query Neighborhood Hits	154	Target Neighborhood Hits	117	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSB11_MOUSE
θ value	5.07402e-19 (rank : 14)	NC score	0.683967 (rank : 15)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL8_HUMAN
θ value	8.65492e-19 (rank : 15)	NC score	0.676271 (rank : 16)
Query Neighborhood Hits	154	Target Neighborhood Hits	289	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSB10_HUMAN
θ value	1.92812e-18 (rank : 16)	NC score	0.688964 (rank : 13)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSBL5_MOUSE
θ value	3.28887e-18 (rank : 17)	NC score	0.687657 (rank : 14)
Query Neighborhood Hits	154	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSB11_HUMAN
θ value	9.56915e-18 (rank : 18)	NC score	0.674134 (rank : 17)
Query Neighborhood Hits	154	Target Neighborhood Hits	60	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

PKHA3_MOUSE
θ value	1.24977e-17 (rank : 19)	NC score	0.562748 (rank : 20)
Query Neighborhood Hits	154	Target Neighborhood Hits	67	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
θ value	2.20605e-14 (rank : 20)	NC score	0.543696 (rank : 21)
Query Neighborhood Hits	154	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_MOUSE
θ value	1.42992e-13 (rank : 21)	NC score	0.480458 (rank : 23)
Query Neighborhood Hits	154	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_HUMAN
θ value	2.43908e-13 (rank : 22)	NC score	0.484080 (rank : 22)
Query Neighborhood Hits	154	Target Neighborhood Hits	87	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

OSBL9_HUMAN
θ value	2.0648e-12 (rank : 23)	NC score	0.696481 (rank : 11)
Query Neighborhood Hits	154	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

MYO10_HUMAN
θ value	1.09739e-05 (rank : 24)	NC score	0.072827 (rank : 67)
Query Neighborhood Hits	154	Target Neighborhood Hits	920	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

TARA_MOUSE
θ value	3.19293e-05 (rank : 25)	NC score	0.108689 (rank : 39)
Query Neighborhood Hits	154	Target Neighborhood Hits	1133	Shared Neighborhood Hits	71
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CYH4_HUMAN
θ value	0.00298849 (rank : 26)	NC score	0.126123 (rank : 27)
Query Neighborhood Hits	154	Target Neighborhood Hits	135	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
θ value	0.00869519 (rank : 27)	NC score	0.127087 (rank : 26)
Query Neighborhood Hits	154	Target Neighborhood Hits	134	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

MRIP_MOUSE
θ value	0.00869519 (rank : 28)	NC score	0.095033 (rank : 52)
Query Neighborhood Hits	154	Target Neighborhood Hits	569	Shared Neighborhood Hits	53
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

PKHA6_HUMAN
θ value	0.00869519 (rank : 29)	NC score	0.154608 (rank : 24)
Query Neighborhood Hits	154	Target Neighborhood Hits	556	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MTMRD_HUMAN
θ value	0.0148317 (rank : 30)	NC score	0.110029 (rank : 37)
Query Neighborhood Hits	154	Target Neighborhood Hits	135	Shared Neighborhood Hits	48
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

DDEF1_MOUSE
θ value	0.0252991 (rank : 31)	NC score	0.116416 (rank : 34)
Query Neighborhood Hits	154	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

PKHA6_MOUSE
θ value	0.0252991 (rank : 32)	NC score	0.145333 (rank : 25)
Query Neighborhood Hits	154	Target Neighborhood Hits	591	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CEND2_HUMAN
θ value	0.0431538 (rank : 33)	NC score	0.076024 (rank : 64)
Query Neighborhood Hits	154	Target Neighborhood Hits	166	Shared Neighborhood Hits	42
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

SWP70_MOUSE
θ value	0.0431538 (rank : 34)	NC score	0.113391 (rank : 36)
Query Neighborhood Hits	154	Target Neighborhood Hits	1097	Shared Neighborhood Hits	77
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

OGFR_HUMAN
θ value	0.0563607 (rank : 35)	NC score	0.022624 (rank : 95)
Query Neighborhood Hits	154	Target Neighborhood Hits	1582	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SWP70_HUMAN
θ value	0.0563607 (rank : 36)	NC score	0.117200 (rank : 33)
Query Neighborhood Hits	154	Target Neighborhood Hits	973	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

URP2_MOUSE
θ value	0.0563607 (rank : 37)	NC score	0.072664 (rank : 68)
Query Neighborhood Hits	154	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

PKHB1_MOUSE
θ value	0.0736092 (rank : 38)	NC score	0.117490 (rank : 31)
Query Neighborhood Hits	154	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

UBF1_HUMAN
θ value	0.0961366 (rank : 39)	NC score	0.031218 (rank : 86)
Query Neighborhood Hits	154	Target Neighborhood Hits	415	Shared Neighborhood Hits	13
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

CEND1_HUMAN
θ value	0.125558 (rank : 40)	NC score	0.074534 (rank : 65)
Query Neighborhood Hits	154	Target Neighborhood Hits	284	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

PKHB1_HUMAN
θ value	0.125558 (rank : 41)	NC score	0.115772 (rank : 35)
Query Neighborhood Hits	154	Target Neighborhood Hits	46	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

RHG25_MOUSE
θ value	0.125558 (rank : 42)	NC score	0.104371 (rank : 42)
Query Neighborhood Hits	154	Target Neighborhood Hits	492	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CENB1_HUMAN
θ value	0.163984 (rank : 43)	NC score	0.064861 (rank : 72)
Query Neighborhood Hits	154	Target Neighborhood Hits	383	Shared Neighborhood Hits	50
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CYH3_MOUSE
θ value	0.163984 (rank : 44)	NC score	0.109913 (rank : 38)
Query Neighborhood Hits	154	Target Neighborhood Hits	148	Shared Neighborhood Hits	58
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

DREB_MOUSE
θ value	0.163984 (rank : 45)	NC score	0.047470 (rank : 81)
Query Neighborhood Hits	154	Target Neighborhood Hits	446	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MK15_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.002559 (rank : 154)
Query Neighborhood Hits	154	Target Neighborhood Hits	1038	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

MRIP_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.086719 (rank : 57)
Query Neighborhood Hits	154	Target Neighborhood Hits	578	Shared Neighborhood Hits	58
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

DDEF2_HUMAN
θ value	0.21417 (rank : 48)	NC score	0.085670 (rank : 59)
Query Neighborhood Hits	154	Target Neighborhood Hits	599	Shared Neighborhood Hits	39
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.21417 (rank : 49)	NC score	0.086502 (rank : 58)
Query Neighborhood Hits	154	Target Neighborhood Hits	625	Shared Neighborhood Hits	45
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DREB_HUMAN
θ value	0.21417 (rank : 50)	NC score	0.046110 (rank : 82)
Query Neighborhood Hits	154	Target Neighborhood Hits	450	Shared Neighborhood Hits	20
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

PCLO_MOUSE
θ value	0.21417 (rank : 51)	NC score	0.023727 (rank : 93)
Query Neighborhood Hits	154	Target Neighborhood Hits	2275	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RHG25_HUMAN
θ value	0.21417 (rank : 52)	NC score	0.100473 (rank : 43)
Query Neighborhood Hits	154	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA4_HUMAN
θ value	0.279714 (rank : 53)	NC score	0.125267 (rank : 28)
Query Neighborhood Hits	154	Target Neighborhood Hits	283	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

TCF19_HUMAN
θ value	0.279714 (rank : 54)	NC score	0.034312 (rank : 84)
Query Neighborhood Hits	154	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

ZCH10_HUMAN
θ value	0.279714 (rank : 55)	NC score	0.047500 (rank : 80)
Query Neighborhood Hits	154	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

CSKI2_MOUSE
θ value	0.365318 (rank : 56)	NC score	0.035418 (rank : 83)
Query Neighborhood Hits	154	Target Neighborhood Hits	812	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GAB2_MOUSE
θ value	0.47712 (rank : 57)	NC score	0.097851 (rank : 46)
Query Neighborhood Hits	154	Target Neighborhood Hits	220	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

MYCN_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.021909 (rank : 96)
Query Neighborhood Hits	154	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

DAPP1_MOUSE
θ value	0.62314 (rank : 59)	NC score	0.087843 (rank : 56)
Query Neighborhood Hits	154	Target Neighborhood Hits	225	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

IWS1_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.020814 (rank : 99)
Query Neighborhood Hits	154	Target Neighborhood Hits	1258	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PCLO_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.023761 (rank : 92)
Query Neighborhood Hits	154	Target Neighborhood Hits	2046	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SUHW4_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.003723 (rank : 149)
Query Neighborhood Hits	154	Target Neighborhood Hits	737	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

URP2_HUMAN
θ value	0.62314 (rank : 63)	NC score	0.060591 (rank : 77)
Query Neighborhood Hits	154	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

ZN592_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.002559 (rank : 153)
Query Neighborhood Hits	154	Target Neighborhood Hits	762	Shared Neighborhood Hits	11
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

BCL9_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.016784 (rank : 103)
Query Neighborhood Hits	154	Target Neighborhood Hits	1008	Shared Neighborhood Hits	24
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

DOCK9_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.032915 (rank : 85)
Query Neighborhood Hits	154	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

PLEK2_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.124356 (rank : 30)
Query Neighborhood Hits	154	Target Neighborhood Hits	101	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	0.813845 (rank : 68)	NC score	0.125155 (rank : 29)
Query Neighborhood Hits	154	Target Neighborhood Hits	96	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

CLSPN_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.028674 (rank : 88)
Query Neighborhood Hits	154	Target Neighborhood Hits	433	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CYH2_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.095168 (rank : 51)
Query Neighborhood Hits	154	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	1.06291 (rank : 71)	NC score	0.095184 (rank : 50)
Query Neighborhood Hits	154	Target Neighborhood Hits	171	Shared Neighborhood Hits	56
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

DAPP1_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.076943 (rank : 63)
Query Neighborhood Hits	154	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA2_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.107464 (rank : 40)
Query Neighborhood Hits	154	Target Neighborhood Hits	116	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_MOUSE
θ value	1.06291 (rank : 74)	NC score	0.117438 (rank : 32)
Query Neighborhood Hits	154	Target Neighborhood Hits	202	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHB2_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.083306 (rank : 61)
Query Neighborhood Hits	154	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

GASP2_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.015368 (rank : 108)
Query Neighborhood Hits	154	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q96D09, Q8NAB4	Gene names	GPRASP2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

NBR1_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.018050 (rank : 101)
Query Neighborhood Hits	154	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

NFL_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.004766 (rank : 146)
Query Neighborhood Hits	154	Target Neighborhood Hits	666	Shared Neighborhood Hits	20
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

PI5PA_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.015484 (rank : 107)
Query Neighborhood Hits	154	Target Neighborhood Hits	749	Shared Neighborhood Hits	27
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

TARA_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.073512 (rank : 66)
Query Neighborhood Hits	154	Target Neighborhood Hits	1626	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CEND1_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.055318 (rank : 78)
Query Neighborhood Hits	154	Target Neighborhood Hits	260	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CLSPN_MOUSE
θ value	1.81305 (rank : 82)	NC score	0.025678 (rank : 90)
Query Neighborhood Hits	154	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

CYH1_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.095594 (rank : 49)
Query Neighborhood Hits	154	Target Neighborhood Hits	184	Shared Neighborhood Hits	58
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.093472 (rank : 53)
Query Neighborhood Hits	154	Target Neighborhood Hits	176	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

KIT_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.000305 (rank : 159)
Query Neighborhood Hits	154	Target Neighborhood Hits	953	Shared Neighborhood Hits	11
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

MK07_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.002088 (rank : 157)
Query Neighborhood Hits	154	Target Neighborhood Hits	1087	Shared Neighborhood Hits	25
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MK07_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.001869 (rank : 158)
Query Neighborhood Hits	154	Target Neighborhood Hits	1054	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

PGCB_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.007719 (rank : 129)
Query Neighborhood Hits	154	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PITM2_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.009577 (rank : 125)
Query Neighborhood Hits	154	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

PKHA2_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.099311 (rank : 44)
Query Neighborhood Hits	154	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

RASF1_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.010957 (rank : 119)
Query Neighborhood Hits	154	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

SON_MOUSE
θ value	1.81305 (rank : 92)	NC score	0.016585 (rank : 104)
Query Neighborhood Hits	154	Target Neighborhood Hits	957	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TRI14_HUMAN
θ value	1.81305 (rank : 93)	NC score	0.006923 (rank : 135)
Query Neighborhood Hits	154	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

CNKR2_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.066009 (rank : 71)
Query Neighborhood Hits	154	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.066058 (rank : 70)
Query Neighborhood Hits	154	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

DHX30_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.010612 (rank : 120)
Query Neighborhood Hits	154	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

MTMR5_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.064313 (rank : 74)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	40
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

NCOA6_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.021905 (rank : 97)
Query Neighborhood Hits	154	Target Neighborhood Hits	1076	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PKHA5_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.105649 (rank : 41)
Query Neighborhood Hits	154	Target Neighborhood Hits	455	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RUSC2_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.014883 (rank : 110)
Query Neighborhood Hits	154	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SCN5A_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.006160 (rank : 137)
Query Neighborhood Hits	154	Target Neighborhood Hits	145	Shared Neighborhood Hits	10
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SRP19_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.028784 (rank : 87)
Query Neighborhood Hits	154	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P09132, Q96FG6	Gene names	SRP19
Domain Architecture
Description	Signal recognition particle 19 kDa protein (SRP19).

AP3B1_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.013422 (rank : 114)
Query Neighborhood Hits	154	Target Neighborhood Hits	302	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CAF1A_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.013601 (rank : 113)
Query Neighborhood Hits	154	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DHX30_MOUSE
θ value	3.0926 (rank : 105)	NC score	0.010223 (rank : 122)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

FRMD5_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.005438 (rank : 140)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

GAB2_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.083538 (rank : 60)
Query Neighborhood Hits	154	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

NCOA6_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.019795 (rank : 100)
Query Neighborhood Hits	154	Target Neighborhood Hits	1202	Shared Neighborhood Hits	36
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

AAK1_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.002243 (rank : 156)
Query Neighborhood Hits	154	Target Neighborhood Hits	1051	Shared Neighborhood Hits	22
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

CYH3_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.091214 (rank : 54)
Query Neighborhood Hits	154	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

NF2L2_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.011294 (rank : 117)
Query Neighborhood Hits	154	Target Neighborhood Hits	183	Shared Neighborhood Hits	12
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

PLXB1_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.005465 (rank : 139)
Query Neighborhood Hits	154	Target Neighborhood Hits	360	Shared Neighborhood Hits	13
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

SRP19_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.025715 (rank : 89)
Query Neighborhood Hits	154	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7A6	Gene names	Srp19
Domain Architecture
Description	Signal recognition particle 19 kDa protein (SRP19).

ZHX2_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.007490 (rank : 132)
Query Neighborhood Hits	154	Target Neighborhood Hits	347	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6X8	Gene names	ZHX2, AFR1, KIAA0854, RAF
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

CCNF_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.008250 (rank : 128)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P51944, Q60797, Q60799	Gene names	Ccnf
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

CK024_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.021048 (rank : 98)
Query Neighborhood Hits	154	Target Neighborhood Hits	408	Shared Neighborhood Hits	26
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CNKR1_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.067053 (rank : 69)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

FGD4_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.013131 (rank : 115)
Query Neighborhood Hits	154	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

LIPS_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.017683 (rank : 102)
Query Neighborhood Hits	154	Target Neighborhood Hits	314	Shared Neighborhood Hits	23
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MNT_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.014596 (rank : 111)
Query Neighborhood Hits	154	Target Neighborhood Hits	496	Shared Neighborhood Hits	21
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NASP_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.011264 (rank : 118)
Query Neighborhood Hits	154	Target Neighborhood Hits	709	Shared Neighborhood Hits	20
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PHLB1_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.024403 (rank : 91)
Query Neighborhood Hits	154	Target Neighborhood Hits	1038	Shared Neighborhood Hits	58
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHB2_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.078497 (rank : 62)
Query Neighborhood Hits	154	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PSL1_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.011538 (rank : 116)
Query Neighborhood Hits	154	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

TXLNB_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.009895 (rank : 124)
Query Neighborhood Hits	154	Target Neighborhood Hits	912	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

ZAR1_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.015012 (rank : 109)
Query Neighborhood Hits	154	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZIMP7_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.008578 (rank : 127)
Query Neighborhood Hits	154	Target Neighborhood Hits	566	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ASTL_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.007538 (rank : 130)
Query Neighborhood Hits	154	Target Neighborhood Hits	252	Shared Neighborhood Hits	8
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BACH1_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.002245 (rank : 155)
Query Neighborhood Hits	154	Target Neighborhood Hits	289	Shared Neighborhood Hits	4
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

IWS1_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.015965 (rank : 105)
Query Neighborhood Hits	154	Target Neighborhood Hits	1241	Shared Neighborhood Hits	33
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LIMD1_MOUSE
θ value	6.88961 (rank : 131)	NC score	0.003954 (rank : 148)
Query Neighborhood Hits	154	Target Neighborhood Hits	291	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MYCN_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.015762 (rank : 106)
Query Neighborhood Hits	154	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

ORC1_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.010338 (rank : 121)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q13415, Q13471, Q5T0F5	Gene names	ORC1L, ORC1, PARC1
Domain Architecture
Description	Origin recognition complex subunit 1 (Replication control protein 1).

PGCA_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.005880 (rank : 138)
Query Neighborhood Hits	154	Target Neighborhood Hits	821	Shared Neighborhood Hits	29
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PI2R_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.002908 (rank : 151)
Query Neighborhood Hits	154	Target Neighborhood Hits	315	Shared Neighborhood Hits	2
SwissProt Accessions	P43252	Gene names	Ptgir
Domain Architecture
Description	Prostacyclin receptor (Prostanoid IP receptor) (PGI receptor) (Prostaglandin I2 receptor).

SH3K1_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.007537 (rank : 131)
Query Neighborhood Hits	154	Target Neighborhood Hits	341	Shared Neighborhood Hits	11
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

TRHY_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.005428 (rank : 141)
Query Neighborhood Hits	154	Target Neighborhood Hits	1385	Shared Neighborhood Hits	26
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

YETS2_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.009957 (rank : 123)
Query Neighborhood Hits	154	Target Neighborhood Hits	278	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZF106_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.003300 (rank : 150)
Query Neighborhood Hits	154	Target Neighborhood Hits	472	Shared Neighborhood Hits	7
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

AATK_HUMAN
θ value	8.99809 (rank : 140)	NC score	-0.000178 (rank : 160)
Query Neighborhood Hits	154	Target Neighborhood Hits	1243	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AKT1_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.004804 (rank : 145)
Query Neighborhood Hits	154	Target Neighborhood Hits	878	Shared Neighborhood Hits	41
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

ARHGC_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.002646 (rank : 152)
Query Neighborhood Hits	154	Target Neighborhood Hits	344	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CAC1F_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.005007 (rank : 144)
Query Neighborhood Hits	154	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CEP35_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.008652 (rank : 126)
Query Neighborhood Hits	154	Target Neighborhood Hits	811	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CYLN2_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.006875 (rank : 136)
Query Neighborhood Hits	154	Target Neighborhood Hits	1004	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.005067 (rank : 143)
Query Neighborhood Hits	154	Target Neighborhood Hits	1002	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DLGP1_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.007105 (rank : 134)
Query Neighborhood Hits	154	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O14490, O14489, P78335	Gene names	DLGAP1, DAP1, GKAP
Domain Architecture
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD- 95/SAP90-binding protein 1).

DLGP1_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.007249 (rank : 133)
Query Neighborhood Hits	154	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D415, Q52KF6, Q5DTK5, Q6P6N4, Q6XBF4, Q8BZL7, Q8BZQ1, Q8C0G0	Gene names	Dlgap1, Kiaa4162
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD-95/SAP90- binding protein 1).

JHD2B_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.004524 (rank : 147)
Query Neighborhood Hits	154	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

MYLK_MOUSE
θ value	8.99809 (rank : 150)	NC score	-0.002629 (rank : 161)
Query Neighborhood Hits	154	Target Neighborhood Hits	1489	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NACAM_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.014270 (rank : 112)
Query Neighborhood Hits	154	Target Neighborhood Hits	1866	Shared Neighborhood Hits	49
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PLEK_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.098373 (rank : 45)
Query Neighborhood Hits	154	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

RASA2_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.022917 (rank : 94)
Query Neighborhood Hits	154	Target Neighborhood Hits	159	Shared Neighborhood Hits	28
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

SYAC_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.005394 (rank : 142)
Query Neighborhood Hits	154	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P49588, Q53GV7, Q96FA0	Gene names	AARS
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (NY-REN-42 antigen).

CENB5_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.062206 (rank : 75)
Query Neighborhood Hits	154	Target Neighborhood Hits	395	Shared Neighborhood Hits	51
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

DDFL1_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.060987 (rank : 76)
Query Neighborhood Hits	154	Target Neighborhood Hits	353	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.064760 (rank : 73)
Query Neighborhood Hits	154	Target Neighborhood Hits	324	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

PKHA1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.096429 (rank : 47)
Query Neighborhood Hits	154	Target Neighborhood Hits	127	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.089847 (rank : 55)
Query Neighborhood Hits	154	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.096337 (rank : 48)
Query Neighborhood Hits	154	Target Neighborhood Hits	110	Shared Neighborhood Hits	47
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

TBCD2_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.051127 (rank : 79)
Query Neighborhood Hits	154	Target Neighborhood Hits	419	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

Hits sorted by NC score

OSBP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	154
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
NC score	0.985261 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	154	Target Neighborhood Hits	150	Shared Neighborhood Hits	72
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBP1_HUMAN
NC score	0.974829 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	154	Target Neighborhood Hits	180	Shared Neighborhood Hits	69
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL2_MOUSE
NC score	0.904219 (rank : 4)	θ value	1.15091e-71 (rank : 8)
Query Neighborhood Hits	154	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_HUMAN
NC score	0.904191 (rank : 5)	θ value	5.71191e-71 (rank : 10)
Query Neighborhood Hits	154	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL7_HUMAN
NC score	0.900312 (rank : 6)	θ value	8.53533e-67 (rank : 12)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL3_MOUSE
NC score	0.893588 (rank : 7)	θ value	2.09745e-73 (rank : 6)
Query Neighborhood Hits	154	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL3_HUMAN
NC score	0.890017 (rank : 8)	θ value	5.71191e-71 (rank : 11)
Query Neighborhood Hits	154	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_HUMAN
NC score	0.885711 (rank : 9)	θ value	3.95564e-72 (rank : 7)
Query Neighborhood Hits	154	Target Neighborhood Hits	101	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
NC score	0.883123 (rank : 10)	θ value	4.37348e-71 (rank : 9)
Query Neighborhood Hits	154	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL9_HUMAN
NC score	0.696481 (rank : 11)	θ value	2.0648e-12 (rank : 23)
Query Neighborhood Hits	154	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBL5_HUMAN
NC score	0.692080 (rank : 12)	θ value	1.09232e-21 (rank : 13)
Query Neighborhood Hits	154	Target Neighborhood Hits	117	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSB10_HUMAN
NC score	0.688964 (rank : 13)	θ value	1.92812e-18 (rank : 16)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSBL5_MOUSE
NC score	0.687657 (rank : 14)	θ value	3.28887e-18 (rank : 17)
Query Neighborhood Hits	154	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSB11_MOUSE
NC score	0.683967 (rank : 15)	θ value	5.07402e-19 (rank : 14)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL8_HUMAN
NC score	0.676271 (rank : 16)	θ value	8.65492e-19 (rank : 15)
Query Neighborhood Hits	154	Target Neighborhood Hits	289	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSB11_HUMAN
NC score	0.674134 (rank : 17)	θ value	9.56915e-18 (rank : 18)
Query Neighborhood Hits	154	Target Neighborhood Hits	60	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL1_MOUSE
NC score	0.641662 (rank : 18)	θ value	1.49618e-87 (rank : 5)
Query Neighborhood Hits	154	Target Neighborhood Hits	336	Shared Neighborhood Hits	33
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_HUMAN
NC score	0.626779 (rank : 19)	θ value	1.35324e-88 (rank : 4)
Query Neighborhood Hits	154	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PKHA3_MOUSE
NC score	0.562748 (rank : 20)	θ value	1.24977e-17 (rank : 19)
Query Neighborhood Hits	154	Target Neighborhood Hits	67	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
NC score	0.543696 (rank : 21)	θ value	2.20605e-14 (rank : 20)
Query Neighborhood Hits	154	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_HUMAN
NC score	0.484080 (rank : 22)	θ value	2.43908e-13 (rank : 22)
Query Neighborhood Hits	154	Target Neighborhood Hits	87	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
NC score	0.480458 (rank : 23)	θ value	1.42992e-13 (rank : 21)
Query Neighborhood Hits	154	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

PKHA6_HUMAN
NC score	0.154608 (rank : 24)	θ value	0.00869519 (rank : 29)
Query Neighborhood Hits	154	Target Neighborhood Hits	556	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.145333 (rank : 25)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	154	Target Neighborhood Hits	591	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CYH4_MOUSE
NC score	0.127087 (rank : 26)	θ value	0.00869519 (rank : 27)
Query Neighborhood Hits	154	Target Neighborhood Hits	134	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.126123 (rank : 27)	θ value	0.00298849 (rank : 26)
Query Neighborhood Hits	154	Target Neighborhood Hits	135	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

PKHA4_HUMAN
NC score	0.125267 (rank : 28)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	154	Target Neighborhood Hits	283	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PLEK2_MOUSE
NC score	0.125155 (rank : 29)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	154	Target Neighborhood Hits	96	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
NC score	0.124356 (rank : 30)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	154	Target Neighborhood Hits	101	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PKHB1_MOUSE
NC score	0.117490 (rank : 31)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	154	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHA4_MOUSE
NC score	0.117438 (rank : 32)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	154	Target Neighborhood Hits	202	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SWP70_HUMAN
NC score	0.117200 (rank : 33)	θ value	0.0563607 (rank : 36)
Query Neighborhood Hits	154	Target Neighborhood Hits	973	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

DDEF1_MOUSE
NC score	0.116416 (rank : 34)	θ value	0.0252991 (rank : 31)
Query Neighborhood Hits	154	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

PKHB1_HUMAN
NC score	0.115772 (rank : 35)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	154	Target Neighborhood Hits	46	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

SWP70_MOUSE
NC score	0.113391 (rank : 36)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	154	Target Neighborhood Hits	1097	Shared Neighborhood Hits	77
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

MTMRD_HUMAN
NC score	0.110029 (rank : 37)	θ value	0.0148317 (rank : 30)
Query Neighborhood Hits	154	Target Neighborhood Hits	135	Shared Neighborhood Hits	48
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

CYH3_MOUSE
NC score	0.109913 (rank : 38)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	154	Target Neighborhood Hits	148	Shared Neighborhood Hits	58
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

TARA_MOUSE
NC score	0.108689 (rank : 39)	θ value	3.19293e-05 (rank : 25)
Query Neighborhood Hits	154	Target Neighborhood Hits	1133	Shared Neighborhood Hits	71
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PKHA2_MOUSE
NC score	0.107464 (rank : 40)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	154	Target Neighborhood Hits	116	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA5_HUMAN
NC score	0.105649 (rank : 41)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	154	Target Neighborhood Hits	455	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RHG25_MOUSE
NC score	0.104371 (rank : 42)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	154	Target Neighborhood Hits	492	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.100473 (rank : 43)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	154	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA2_HUMAN
NC score	0.099311 (rank : 44)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	154	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PLEK_MOUSE
NC score	0.098373 (rank : 45)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	154	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

GAB2_MOUSE
NC score	0.097851 (rank : 46)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	154	Target Neighborhood Hits	220	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PKHA1_HUMAN
NC score	0.096429 (rank : 47)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	154	Target Neighborhood Hits	127	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK_HUMAN
NC score	0.096337 (rank : 48)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	154	Target Neighborhood Hits	110	Shared Neighborhood Hits	47
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

CYH1_HUMAN
NC score	0.095594 (rank : 49)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	154	Target Neighborhood Hits	184	Shared Neighborhood Hits	58
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH2_MOUSE
NC score	0.095184 (rank : 50)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	154	Target Neighborhood Hits	171	Shared Neighborhood Hits	56
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH2_HUMAN
NC score	0.095168 (rank : 51)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	154	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

MRIP_MOUSE
NC score	0.095033 (rank : 52)	θ value	0.00869519 (rank : 28)
Query Neighborhood Hits	154	Target Neighborhood Hits	569	Shared Neighborhood Hits	53
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

CYH1_MOUSE
NC score	0.093472 (rank : 53)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	154	Target Neighborhood Hits	176	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
NC score	0.091214 (rank : 54)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	154	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

PKHA1_MOUSE
NC score	0.089847 (rank : 55)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	154	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

DAPP1_MOUSE
NC score	0.087843 (rank : 56)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	154	Target Neighborhood Hits	225	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

MRIP_HUMAN
NC score	0.086719 (rank : 57)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	154	Target Neighborhood Hits	578	Shared Neighborhood Hits	58
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

DDEF2_MOUSE
NC score	0.086502 (rank : 58)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	154	Target Neighborhood Hits	625	Shared Neighborhood Hits	45
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_HUMAN
NC score	0.085670 (rank : 59)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	154	Target Neighborhood Hits	599	Shared Neighborhood Hits	39
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

GAB2_HUMAN
NC score	0.083538 (rank : 60)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	154	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

PKHB2_MOUSE
NC score	0.083306 (rank : 61)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	154	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PKHB2_HUMAN
NC score	0.078497 (rank : 62)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	154	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

DAPP1_HUMAN
NC score	0.076943 (rank : 63)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	154	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CEND2_HUMAN
NC score	0.076024 (rank : 64)	θ value	0.0431538 (rank : 33)
Query Neighborhood Hits	154	Target Neighborhood Hits	166	Shared Neighborhood Hits	42
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND1_HUMAN
NC score	0.074534 (rank : 65)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	154	Target Neighborhood Hits	284	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

TARA_HUMAN
NC score	0.073512 (rank : 66)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	154	Target Neighborhood Hits	1626	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MYO10_HUMAN
NC score	0.072827 (rank : 67)	θ value	1.09739e-05 (rank : 24)
Query Neighborhood Hits	154	Target Neighborhood Hits	920	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

URP2_MOUSE
NC score	0.072664 (rank : 68)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	154	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

CNKR1_HUMAN
NC score	0.067053 (rank : 69)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_MOUSE
NC score	0.066058 (rank : 70)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	154	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.066009 (rank : 71)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	154	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CENB1_HUMAN
NC score	0.064861 (rank : 72)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	154	Target Neighborhood Hits	383	Shared Neighborhood Hits	50
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DDFL1_MOUSE
NC score	0.064760 (rank : 73)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	154	Target Neighborhood Hits	324	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

MTMR5_HUMAN
NC score	0.064313 (rank : 74)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	40
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

CENB5_HUMAN
NC score	0.062206 (rank : 75)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	154	Target Neighborhood Hits	395	Shared Neighborhood Hits	51
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

DDFL1_HUMAN
NC score	0.060987 (rank : 76)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	154	Target Neighborhood Hits	353	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

URP2_HUMAN
NC score	0.060591 (rank : 77)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	154	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

CEND1_MOUSE
NC score	0.055318 (rank : 78)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	154	Target Neighborhood Hits	260	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

TBCD2_HUMAN
NC score	0.051127 (rank : 79)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	154	Target Neighborhood Hits	419	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

ZCH10_HUMAN
NC score	0.047500 (rank : 80)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	154	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

DREB_MOUSE
NC score	0.047470 (rank : 81)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	154	Target Neighborhood Hits	446	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DREB_HUMAN
NC score	0.046110 (rank : 82)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	154	Target Neighborhood Hits	450	Shared Neighborhood Hits	20
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

CSKI2_MOUSE
NC score	0.035418 (rank : 83)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	154	Target Neighborhood Hits	812	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TCF19_HUMAN
NC score	0.034312 (rank : 84)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	154	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

DOCK9_HUMAN
NC score	0.032915 (rank : 85)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	154	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

UBF1_HUMAN
NC score	0.031218 (rank : 86)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	154	Target Neighborhood Hits	415	Shared Neighborhood Hits	13
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

SRP19_HUMAN
NC score	0.028784 (rank : 87)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	154	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P09132, Q96FG6	Gene names	SRP19
Domain Architecture
Description	Signal recognition particle 19 kDa protein (SRP19).

CLSPN_HUMAN
NC score	0.028674 (rank : 88)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	154	Target Neighborhood Hits	433	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

SRP19_MOUSE
NC score	0.025715 (rank : 89)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	154	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7A6	Gene names	Srp19
Domain Architecture
Description	Signal recognition particle 19 kDa protein (SRP19).

CLSPN_MOUSE
NC score	0.025678 (rank : 90)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	154	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

PHLB1_HUMAN
NC score	0.024403 (rank : 91)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	154	Target Neighborhood Hits	1038	Shared Neighborhood Hits	58
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PCLO_HUMAN
NC score	0.023761 (rank : 92)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	154	Target Neighborhood Hits	2046	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
NC score	0.023727 (rank : 93)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	154	Target Neighborhood Hits	2275	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RASA2_MOUSE
NC score	0.022917 (rank : 94)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	154	Target Neighborhood Hits	159	Shared Neighborhood Hits	28
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

OGFR_HUMAN
NC score	0.022624 (rank : 95)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	154	Target Neighborhood Hits	1582	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MYCN_MOUSE
NC score	0.021909 (rank : 96)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	154	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

NCOA6_MOUSE
NC score	0.021905 (rank : 97)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	154	Target Neighborhood Hits	1076	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

CK024_HUMAN
NC score	0.021048 (rank : 98)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	154	Target Neighborhood Hits	408	Shared Neighborhood Hits	26
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

IWS1_MOUSE
NC score	0.020814 (rank : 99)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	154	Target Neighborhood Hits	1258	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NCOA6_HUMAN
NC score	0.019795 (rank : 100)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	154	Target Neighborhood Hits	1202	Shared Neighborhood Hits	36
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NBR1_MOUSE
NC score	0.018050 (rank : 101)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	154	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

LIPS_HUMAN
NC score	0.017683 (rank : 102)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	154	Target Neighborhood Hits	314	Shared Neighborhood Hits	23
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

BCL9_HUMAN
NC score	0.016784 (rank : 103)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	154	Target Neighborhood Hits	1008	Shared Neighborhood Hits	24
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

SON_MOUSE
NC score	0.016585 (rank : 104)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	154	Target Neighborhood Hits	957	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

IWS1_HUMAN
NC score	0.015965 (rank : 105)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	154	Target Neighborhood Hits	1241	Shared Neighborhood Hits	33
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYCN_HUMAN
NC score	0.015762 (rank : 106)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	154	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

PI5PA_HUMAN
NC score	0.015484 (rank : 107)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	154	Target Neighborhood Hits	749	Shared Neighborhood Hits	27
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

GASP2_HUMAN
NC score	0.015368 (rank : 108)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	154	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q96D09, Q8NAB4	Gene names	GPRASP2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

ZAR1_MOUSE
NC score	0.015012 (rank : 109)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	154	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

RUSC2_HUMAN
NC score	0.014883 (rank : 110)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	154	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

MNT_HUMAN
NC score	0.014596 (rank : 111)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	154	Target Neighborhood Hits	496	Shared Neighborhood Hits	21
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NACAM_MOUSE
NC score	0.014270 (rank : 112)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	154	Target Neighborhood Hits	1866	Shared Neighborhood Hits	49
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CAF1A_HUMAN
NC score	0.013601 (rank : 113)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	154	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

AP3B1_MOUSE
NC score	0.013422 (rank : 114)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	154	Target Neighborhood Hits	302	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

FGD4_MOUSE
NC score	0.013131 (rank : 115)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	154	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

PSL1_HUMAN
NC score	0.011538 (rank : 116)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	154	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

NF2L2_MOUSE
NC score	0.011294 (rank : 117)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	154	Target Neighborhood Hits	183	Shared Neighborhood Hits	12
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

NASP_HUMAN
NC score	0.011264 (rank : 118)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	154	Target Neighborhood Hits	709	Shared Neighborhood Hits	20
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

RASF1_MOUSE
NC score	0.010957 (rank : 119)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	154	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

DHX30_HUMAN
NC score	0.010612 (rank : 120)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	154	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

ORC1_HUMAN
NC score	0.010338 (rank : 121)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q13415, Q13471, Q5T0F5	Gene names	ORC1L, ORC1, PARC1
Domain Architecture
Description	Origin recognition complex subunit 1 (Replication control protein 1).

DHX30_MOUSE
NC score	0.010223 (rank : 122)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

YETS2_MOUSE
NC score	0.009957 (rank : 123)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	154	Target Neighborhood Hits	278	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

TXLNB_HUMAN
NC score	0.009895 (rank : 124)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	154	Target Neighborhood Hits	912	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

PITM2_HUMAN
NC score	0.009577 (rank : 125)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	154	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

CEP35_HUMAN
NC score	0.008652 (rank : 126)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	154	Target Neighborhood Hits	811	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

ZIMP7_MOUSE
NC score	0.008578 (rank : 127)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	154	Target Neighborhood Hits	566	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CCNF_MOUSE
NC score	0.008250 (rank : 128)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P51944, Q60797, Q60799	Gene names	Ccnf
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

PGCB_HUMAN
NC score	0.007719 (rank : 129)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	154	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

ASTL_HUMAN
NC score	0.007538 (rank : 130)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	154	Target Neighborhood Hits	252	Shared Neighborhood Hits	8
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

SH3K1_HUMAN
NC score	0.007537 (rank : 131)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	154	Target Neighborhood Hits	341	Shared Neighborhood Hits	11
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

ZHX2_HUMAN
NC score	0.007490 (rank : 132)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	154	Target Neighborhood Hits	347	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6X8	Gene names	ZHX2, AFR1, KIAA0854, RAF
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

DLGP1_MOUSE
NC score	0.007249 (rank : 133)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	154	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D415, Q52KF6, Q5DTK5, Q6P6N4, Q6XBF4, Q8BZL7, Q8BZQ1, Q8C0G0	Gene names	Dlgap1, Kiaa4162
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD-95/SAP90- binding protein 1).

DLGP1_HUMAN
NC score	0.007105 (rank : 134)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	154	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O14490, O14489, P78335	Gene names	DLGAP1, DAP1, GKAP
Domain Architecture
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD- 95/SAP90-binding protein 1).

TRI14_HUMAN
NC score	0.006923 (rank : 135)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	154	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

CYLN2_HUMAN
NC score	0.006875 (rank : 136)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	154	Target Neighborhood Hits	1004	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

SCN5A_HUMAN
NC score	0.006160 (rank : 137)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	154	Target Neighborhood Hits	145	Shared Neighborhood Hits	10
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

PGCA_HUMAN
NC score	0.005880 (rank : 138)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	154	Target Neighborhood Hits	821	Shared Neighborhood Hits	29
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PLXB1_HUMAN
NC score	0.005465 (rank : 139)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	154	Target Neighborhood Hits	360	Shared Neighborhood Hits	13
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

FRMD5_HUMAN
NC score	0.005438 (rank : 140)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

TRHY_HUMAN
NC score	0.005428 (rank : 141)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	154	Target Neighborhood Hits	1385	Shared Neighborhood Hits	26
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

SYAC_HUMAN
NC score	0.005394 (rank : 142)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	154	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P49588, Q53GV7, Q96FA0	Gene names	AARS
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (NY-REN-42 antigen).

CYLN2_MOUSE
NC score	0.005067 (rank : 143)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	154	Target Neighborhood Hits	1002	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CAC1F_MOUSE
NC score	0.005007 (rank : 144)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	154	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

AKT1_MOUSE
NC score	0.004804 (rank : 145)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	154	Target Neighborhood Hits	878	Shared Neighborhood Hits	41
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

NFL_HUMAN
NC score	0.004766 (rank : 146)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	154	Target Neighborhood Hits	666	Shared Neighborhood Hits	20
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

JHD2B_HUMAN
NC score	0.004524 (rank : 147)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	154	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

LIMD1_MOUSE
NC score	0.003954 (rank : 148)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	154	Target Neighborhood Hits	291	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

SUHW4_MOUSE
NC score	0.003723 (rank : 149)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	154	Target Neighborhood Hits	737	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

ZF106_MOUSE
NC score	0.003300 (rank : 150)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	154	Target Neighborhood Hits	472	Shared Neighborhood Hits	7
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

PI2R_MOUSE
NC score	0.002908 (rank : 151)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	154	Target Neighborhood Hits	315	Shared Neighborhood Hits	2
SwissProt Accessions	P43252	Gene names	Ptgir
Domain Architecture
Description	Prostacyclin receptor (Prostanoid IP receptor) (PGI receptor) (Prostaglandin I2 receptor).

ARHGC_MOUSE
NC score	0.002646 (rank : 152)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	154	Target Neighborhood Hits	344	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ZN592_HUMAN
NC score	0.002559 (rank : 153)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	154	Target Neighborhood Hits	762	Shared Neighborhood Hits	11
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

MK15_HUMAN
NC score	0.002559 (rank : 154)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	154	Target Neighborhood Hits	1038	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

BACH1_MOUSE
NC score	0.002245 (rank : 155)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	154	Target Neighborhood Hits	289	Shared Neighborhood Hits	4
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

AAK1_MOUSE
NC score	0.002243 (rank : 156)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	154	Target Neighborhood Hits	1051	Shared Neighborhood Hits	22
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

MK07_HUMAN
NC score	0.002088 (rank : 157)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	154	Target Neighborhood Hits	1087	Shared Neighborhood Hits	25
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MK07_MOUSE
NC score	0.001869 (rank : 158)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	154	Target Neighborhood Hits	1054	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

KIT_HUMAN
NC score	0.000305 (rank : 159)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	154	Target Neighborhood Hits	953	Shared Neighborhood Hits	11
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

AATK_HUMAN
NC score	-0.000178 (rank : 160)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	154	Target Neighborhood Hits	1243	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

MYLK_MOUSE
NC score	-0.002629 (rank : 161)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	154	Target Neighborhood Hits	1489	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).