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Network neighborhood for query Sequence : URP2_MOUSE

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URP2_MOUSE
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PKHC1_HUMAN
θ value	0 (rank : 1)	NC score	0.979464 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

PKHC1_MOUSE
θ value	0 (rank : 2)	NC score	0.979627 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

URP1_HUMAN
θ value	0 (rank : 3)	NC score	0.980970 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQL6, Q8IX34, Q8IYH2, Q9NWM2, Q9NXQ3	Gene names	URP1, C20orf42, KIND1
Domain Architecture
Description	Unc-112-related protein 1 (Kindlin-1) (Kindlerin) (Kindlin syndrome protein).

URP2_HUMAN
θ value	0 (rank : 4)	NC score	0.997993 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

URP2_MOUSE
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

TLN1_HUMAN
θ value	7.34386e-10 (rank : 6)	NC score	0.332634 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	218	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	9.59137e-10 (rank : 7)	NC score	0.330700 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
θ value	3.64472e-09 (rank : 8)	NC score	0.326038 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	1.38499e-08 (rank : 9)	NC score	0.323232 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

C43BP_MOUSE
θ value	0.00134147 (rank : 10)	NC score	0.135515 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_HUMAN
θ value	0.00869519 (rank : 11)	NC score	0.126249 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

OSBP2_HUMAN
θ value	0.0563607 (rank : 12)	NC score	0.072664 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP1_HUMAN
θ value	0.0736092 (rank : 13)	NC score	0.085491 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	180	Shared Neighborhood Hits	15
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

PKHA3_MOUSE
θ value	0.163984 (rank : 14)	NC score	0.109251 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.111844 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

OSBL8_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.046847 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

FARP1_HUMAN
θ value	0.365318 (rank : 17)	NC score	0.027121 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PGRP2_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.028984 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PD5, Q96N74, Q9UC60	Gene names	PGLYRP2, PGLYRPL, PGRPL
Domain Architecture
Description	N-acetylmuramoyl-L-alanine amidase precursor (EC 3.5.1.28) (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2).

OSBP2_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.071971 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

PPOX_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.026197 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

SGPP1_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.022560 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX95, Q9H189	Gene names	SGPP1
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 1 (EC 3.1.3.-) (Sphingosine-1- phosphatase 1) (SPPase1) (Spp1) (hSPPase1).

CSKI1_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.005398 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	997	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MYO10_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.015841 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	920	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

XYLT1_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.016291 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

AB1IP_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.036126 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	213	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AB1IP_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.032299 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

BMX_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.007217 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	942	Shared Neighborhood Hits	12
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.004581 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	912	Shared Neighborhood Hits	12
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

MRIP_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.018907 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	578	Shared Neighborhood Hits	18
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

ARHG6_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.007878 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	394	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

PGH2_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.013245 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

CENA1_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.008356 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

DP13B_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.008360 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

K1914_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.064580 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	255	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

RASL2_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.018007 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

CASP8_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.010047 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O89110, O35669	Gene names	Casp8
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

MYO15_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.004610 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	467	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MESD1_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.098560 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

MESD1_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.101307 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

Hits sorted by NC score

URP2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

URP2_HUMAN
NC score	0.997993 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UX7, Q8IUA1, Q8N207, Q9BT48	Gene names	URP2, KIND3, MIG2B
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3) (MIG2-like).

URP1_HUMAN
NC score	0.980970 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQL6, Q8IX34, Q8IYH2, Q9NWM2, Q9NXQ3	Gene names	URP1, C20orf42, KIND1
Domain Architecture
Description	Unc-112-related protein 1 (Kindlin-1) (Kindlerin) (Kindlin syndrome protein).

PKHC1_MOUSE
NC score	0.979627 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

PKHC1_HUMAN
NC score	0.979464 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

TLN1_HUMAN
NC score	0.332634 (rank : 6)	θ value	7.34386e-10 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	218	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.330700 (rank : 7)	θ value	9.59137e-10 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
NC score	0.326038 (rank : 8)	θ value	3.64472e-09 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
NC score	0.323232 (rank : 9)	θ value	1.38499e-08 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

C43BP_MOUSE
NC score	0.135515 (rank : 10)	θ value	0.00134147 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_HUMAN
NC score	0.126249 (rank : 11)	θ value	0.00869519 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

PKHA3_HUMAN
NC score	0.111844 (rank : 12)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
NC score	0.109251 (rank : 13)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

MESD1_MOUSE
NC score	0.101307 (rank : 14)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

MESD1_HUMAN
NC score	0.098560 (rank : 15)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

OSBP1_HUMAN
NC score	0.085491 (rank : 16)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	180	Shared Neighborhood Hits	15
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBP2_HUMAN
NC score	0.072664 (rank : 17)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
NC score	0.071971 (rank : 18)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

K1914_HUMAN
NC score	0.064580 (rank : 19)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	255	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

OSBL8_HUMAN
NC score	0.046847 (rank : 20)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

AB1IP_HUMAN
NC score	0.036126 (rank : 21)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	213	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AB1IP_MOUSE
NC score	0.032299 (rank : 22)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

PGRP2_HUMAN
NC score	0.028984 (rank : 23)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PD5, Q96N74, Q9UC60	Gene names	PGLYRP2, PGLYRPL, PGRPL
Domain Architecture
Description	N-acetylmuramoyl-L-alanine amidase precursor (EC 3.5.1.28) (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2).

FARP1_HUMAN
NC score	0.027121 (rank : 24)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PPOX_HUMAN
NC score	0.026197 (rank : 25)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

SGPP1_HUMAN
NC score	0.022560 (rank : 26)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX95, Q9H189	Gene names	SGPP1
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 1 (EC 3.1.3.-) (Sphingosine-1- phosphatase 1) (SPPase1) (Spp1) (hSPPase1).

MRIP_HUMAN
NC score	0.018907 (rank : 27)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	578	Shared Neighborhood Hits	18
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

RASL2_HUMAN
NC score	0.018007 (rank : 28)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

XYLT1_HUMAN
NC score	0.016291 (rank : 29)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

MYO10_HUMAN
NC score	0.015841 (rank : 30)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	920	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PGH2_HUMAN
NC score	0.013245 (rank : 31)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

CASP8_MOUSE
NC score	0.010047 (rank : 32)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O89110, O35669	Gene names	Casp8
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

DP13B_MOUSE
NC score	0.008360 (rank : 33)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

CENA1_HUMAN
NC score	0.008356 (rank : 34)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

ARHG6_MOUSE
NC score	0.007878 (rank : 35)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	394	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

BMX_HUMAN
NC score	0.007217 (rank : 36)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	942	Shared Neighborhood Hits	12
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

CSKI1_HUMAN
NC score	0.005398 (rank : 37)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	997	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MYO15_MOUSE
NC score	0.004610 (rank : 38)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	467	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

BMX_MOUSE
NC score	0.004581 (rank : 39)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	912	Shared Neighborhood Hits	12
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).