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Network neighborhood for query Sequence : PPOX_HUMAN

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PPOX_HUMAN
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PPOX_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

PPOX_MOUSE
θ value	0 (rank : 2)	NC score	0.987433 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

AOFB_MOUSE
θ value	9.29e-05 (rank : 3)	NC score	0.263820 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFB_HUMAN
θ value	0.00228821 (rank : 4)	NC score	0.276286 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	20
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_MOUSE
θ value	0.00390308 (rank : 5)	NC score	0.259996 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

PAOX_HUMAN
θ value	0.00509761 (rank : 6)	NC score	0.221378 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

AOFA_HUMAN
θ value	0.0113563 (rank : 7)	NC score	0.237662 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOF1_MOUSE
θ value	0.0330416 (rank : 8)	NC score	0.194930 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

PAOX_MOUSE
θ value	0.0431538 (rank : 9)	NC score	0.221049 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

CJ033_MOUSE
θ value	0.0563607 (rank : 10)	NC score	0.118660 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

OXLA_HUMAN
θ value	0.0961366 (rank : 11)	NC score	0.184382 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

HDAC6_MOUSE
θ value	0.279714 (rank : 12)	NC score	0.032453 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

OXLA_MOUSE
θ value	0.279714 (rank : 13)	NC score	0.181077 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

RETST_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.090024 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NUM9, Q53R95, Q53SA9, Q6UX05, Q8N2H5, Q96FA4, Q9NXE5	Gene names	RETSAT
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

SMOX_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.174476 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.179092 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

LSD1_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.144324 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	455	Shared Neighborhood Hits	16
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.151246 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	224	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

SON_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.032435 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	957	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TYK2_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.008969 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	850	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

AOF1_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.173517 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

URP2_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.026197 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

M2GD_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.042737 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UI17	Gene names	DMGDH
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

SPR1_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.014651 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	601	Shared Neighborhood Hits	4
SwissProt Accessions	Q15743, Q13334, Q6IX34	Gene names	GPR68, OGR1
Domain Architecture
Description	Sphingosylphosphorylcholine receptor (Ovarian cancer G-protein coupled receptor 1) (OGR-1) (G-protein coupled receptor 68) (GPR12A).

FAS_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.024522 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P19096, Q6PB72, Q8C4Z0, Q9EQR0	Gene names	Fasn
Domain Architecture	No domain graphic available
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

M2GD_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.040584 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBT9, Q8R1S7	Gene names	Dmgdh
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

SPR1_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.013957 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	593	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BFQ3, Q3U1L3, Q80T34	Gene names	Gpr68
Domain Architecture
Description	Sphingosylphosphorylcholine receptor (G-protein coupled receptor 68).

RETST_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.079613 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

PRRT3_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.022580 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SON_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.017158 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	1568	Shared Neighborhood Hits	5
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PCYOX_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.044018 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

IQCB1_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.014766 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q15051, Q5DKQ7, Q8NI79, Q9BS08	Gene names	IQCB1, KIAA0036, NPHP5
Domain Architecture
Description	IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5).

MBL2_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.007510 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	P41317	Gene names	Mbl2
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (Mannan-binding protein) (RA-reactive factor P28A subunit) (RARF/P28A).

TF7L2_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.008132 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

ZN628_HUMAN
θ value	8.99809 (rank : 35)	NC score	-0.000606 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	814	Shared Neighborhood Hits	4
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.

CJ033_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.066123 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

Hits sorted by NC score

PPOX_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

PPOX_MOUSE
NC score	0.987433 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

AOFB_HUMAN
NC score	0.276286 (rank : 3)	θ value	0.00228821 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	20
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFB_MOUSE
NC score	0.263820 (rank : 4)	θ value	9.29e-05 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_MOUSE
NC score	0.259996 (rank : 5)	θ value	0.00390308 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFA_HUMAN
NC score	0.237662 (rank : 6)	θ value	0.0113563 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

PAOX_HUMAN
NC score	0.221378 (rank : 7)	θ value	0.00509761 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

PAOX_MOUSE
NC score	0.221049 (rank : 8)	θ value	0.0431538 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

AOF1_MOUSE
NC score	0.194930 (rank : 9)	θ value	0.0330416 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

OXLA_HUMAN
NC score	0.184382 (rank : 10)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

OXLA_MOUSE
NC score	0.181077 (rank : 11)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

SMOX_MOUSE
NC score	0.179092 (rank : 12)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_HUMAN
NC score	0.174476 (rank : 13)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

AOF1_HUMAN
NC score	0.173517 (rank : 14)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

LSD1_MOUSE
NC score	0.151246 (rank : 15)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	224	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_HUMAN
NC score	0.144324 (rank : 16)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	455	Shared Neighborhood Hits	16
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

CJ033_MOUSE
NC score	0.118660 (rank : 17)	θ value	0.0563607 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

RETST_HUMAN
NC score	0.090024 (rank : 18)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NUM9, Q53R95, Q53SA9, Q6UX05, Q8N2H5, Q96FA4, Q9NXE5	Gene names	RETSAT
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

RETST_MOUSE
NC score	0.079613 (rank : 19)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

CJ033_HUMAN
NC score	0.066123 (rank : 20)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

PCYOX_MOUSE
NC score	0.044018 (rank : 21)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

M2GD_HUMAN
NC score	0.042737 (rank : 22)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UI17	Gene names	DMGDH
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

M2GD_MOUSE
NC score	0.040584 (rank : 23)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBT9, Q8R1S7	Gene names	Dmgdh
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

HDAC6_MOUSE
NC score	0.032453 (rank : 24)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

SON_MOUSE
NC score	0.032435 (rank : 25)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	957	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

URP2_MOUSE
NC score	0.026197 (rank : 26)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

FAS_MOUSE
NC score	0.024522 (rank : 27)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P19096, Q6PB72, Q8C4Z0, Q9EQR0	Gene names	Fasn
Domain Architecture	No domain graphic available
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

PRRT3_MOUSE
NC score	0.022580 (rank : 28)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SON_HUMAN
NC score	0.017158 (rank : 29)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	1568	Shared Neighborhood Hits	5
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

IQCB1_HUMAN
NC score	0.014766 (rank : 30)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q15051, Q5DKQ7, Q8NI79, Q9BS08	Gene names	IQCB1, KIAA0036, NPHP5
Domain Architecture
Description	IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5).

SPR1_HUMAN
NC score	0.014651 (rank : 31)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	601	Shared Neighborhood Hits	4
SwissProt Accessions	Q15743, Q13334, Q6IX34	Gene names	GPR68, OGR1
Domain Architecture
Description	Sphingosylphosphorylcholine receptor (Ovarian cancer G-protein coupled receptor 1) (OGR-1) (G-protein coupled receptor 68) (GPR12A).

SPR1_MOUSE
NC score	0.013957 (rank : 32)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	593	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BFQ3, Q3U1L3, Q80T34	Gene names	Gpr68
Domain Architecture
Description	Sphingosylphosphorylcholine receptor (G-protein coupled receptor 68).

TYK2_MOUSE
NC score	0.008969 (rank : 33)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	850	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TF7L2_HUMAN
NC score	0.008132 (rank : 34)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

MBL2_MOUSE
NC score	0.007510 (rank : 35)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	P41317	Gene names	Mbl2
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (Mannan-binding protein) (RA-reactive factor P28A subunit) (RARF/P28A).

ZN628_HUMAN
NC score	-0.000606 (rank : 36)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	814	Shared Neighborhood Hits	4
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.