Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : AOFB_HUMAN

For an explanation of this page, click here

AOFB_HUMAN
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AOFA_HUMAN
θ value	0 (rank : 1)	NC score	0.984078 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFA_MOUSE
θ value	0 (rank : 2)	NC score	0.989564 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFB_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFB_MOUSE
θ value	0 (rank : 4)	NC score	0.992477 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOF1_HUMAN
θ value	3.63628e-17 (rank : 5)	NC score	0.575645 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
θ value	1.38178e-16 (rank : 6)	NC score	0.571861 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

PAOX_MOUSE
θ value	5.43371e-13 (rank : 7)	NC score	0.477695 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

OXLA_MOUSE
θ value	1.33837e-11 (rank : 8)	NC score	0.517341 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

OXLA_HUMAN
θ value	2.28291e-11 (rank : 9)	NC score	0.487189 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

LSD1_HUMAN
θ value	4.76016e-09 (rank : 10)	NC score	0.424625 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	455	Shared Neighborhood Hits	24
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	4.76016e-09 (rank : 11)	NC score	0.443431 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	224	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PAOX_HUMAN
θ value	4.45536e-07 (rank : 12)	NC score	0.397604 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

SMOX_MOUSE
θ value	7.1131e-05 (rank : 13)	NC score	0.370149 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

RETST_HUMAN
θ value	9.29e-05 (rank : 14)	NC score	0.191881 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NUM9, Q53R95, Q53SA9, Q6UX05, Q8N2H5, Q96FA4, Q9NXE5	Gene names	RETSAT
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

SMOX_HUMAN
θ value	9.29e-05 (rank : 15)	NC score	0.379903 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

RETST_MOUSE
θ value	0.000270298 (rank : 16)	NC score	0.183232 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

PCYOX_HUMAN
θ value	0.00175202 (rank : 17)	NC score	0.152196 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHG3, O94982, Q8N4N5, Q96QM8	Gene names	PCYOX1, KIAA0908, PCL1
Domain Architecture
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5) (PCL1).

PCYOX_MOUSE
θ value	0.00175202 (rank : 18)	NC score	0.201390 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

PPOX_HUMAN
θ value	0.00228821 (rank : 19)	NC score	0.276286 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

PPOX_MOUSE
θ value	0.00298849 (rank : 20)	NC score	0.197202 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

CJ033_HUMAN
θ value	0.125558 (rank : 21)	NC score	0.169439 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

CJ033_MOUSE
θ value	0.125558 (rank : 22)	NC score	0.179648 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

FMO5_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.054301 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO3_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.078895 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

FMO2_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.063297 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

RIMB1_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.014384 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	1479	Shared Neighborhood Hits	3
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

FMO1_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.062560 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q01740, Q5QPT2, Q9UJC2	Gene names	FMO1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

L2HDH_MOUSE
θ value	2.36792 (rank : 28)	NC score	0.041786 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YP0, Q3TH61, Q3U7Z0, Q3ULY6	Gene names	L2hgdh
Domain Architecture	No domain graphic available
Description	L-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.2) (Duranin).

RIMB1_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.011094 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	1376	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

FMO2_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.051970 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

KMO_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.025876 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WN4	Gene names	Kmo
Domain Architecture	No domain graphic available
Description	Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase).

L2HDH_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.040448 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9P8, Q9BRR1	Gene names	L2HGDH, C14orf160
Domain Architecture	No domain graphic available
Description	L-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.2) (Duranin).

TRXR1_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.024892 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

FMO4_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.052281 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	P31512	Gene names	FMO4, FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

KMO_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.031100 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	O15229, Q5SY07, Q5SY08, Q5SY09	Gene names	KMO
Domain Architecture	No domain graphic available
Description	Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase).

ETFD_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.020963 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q16134, Q7Z347	Gene names	ETFDH
Domain Architecture
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

FMO1_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.048219 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	P50285	Gene names	Fmo1, Fmo-1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO6_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.047161 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	O60774	Gene names	FMO6
Domain Architecture
Description	Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6).

FMO3_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.053363 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P31513, Q14854, Q8N5N5	Gene names	FMO3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3) (FMO form 2) (FMO II).

Hits sorted by NC score

AOFB_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFB_MOUSE
NC score	0.992477 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_MOUSE
NC score	0.989564 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFA_HUMAN
NC score	0.984078 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOF1_HUMAN
NC score	0.575645 (rank : 5)	θ value	3.63628e-17 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
NC score	0.571861 (rank : 6)	θ value	1.38178e-16 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

OXLA_MOUSE
NC score	0.517341 (rank : 7)	θ value	1.33837e-11 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

OXLA_HUMAN
NC score	0.487189 (rank : 8)	θ value	2.28291e-11 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

PAOX_MOUSE
NC score	0.477695 (rank : 9)	θ value	5.43371e-13 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

LSD1_MOUSE
NC score	0.443431 (rank : 10)	θ value	4.76016e-09 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	224	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_HUMAN
NC score	0.424625 (rank : 11)	θ value	4.76016e-09 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	455	Shared Neighborhood Hits	24
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PAOX_HUMAN
NC score	0.397604 (rank : 12)	θ value	4.45536e-07 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

SMOX_HUMAN
NC score	0.379903 (rank : 13)	θ value	9.29e-05 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_MOUSE
NC score	0.370149 (rank : 14)	θ value	7.1131e-05 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

PPOX_HUMAN
NC score	0.276286 (rank : 15)	θ value	0.00228821 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

PCYOX_MOUSE
NC score	0.201390 (rank : 16)	θ value	0.00175202 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

PPOX_MOUSE
NC score	0.197202 (rank : 17)	θ value	0.00298849 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

RETST_HUMAN
NC score	0.191881 (rank : 18)	θ value	9.29e-05 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NUM9, Q53R95, Q53SA9, Q6UX05, Q8N2H5, Q96FA4, Q9NXE5	Gene names	RETSAT
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

RETST_MOUSE
NC score	0.183232 (rank : 19)	θ value	0.000270298 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

CJ033_MOUSE
NC score	0.179648 (rank : 20)	θ value	0.125558 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

CJ033_HUMAN
NC score	0.169439 (rank : 21)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

PCYOX_HUMAN
NC score	0.152196 (rank : 22)	θ value	0.00175202 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHG3, O94982, Q8N4N5, Q96QM8	Gene names	PCYOX1, KIAA0908, PCL1
Domain Architecture
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5) (PCL1).

FMO3_MOUSE
NC score	0.078895 (rank : 23)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

FMO2_MOUSE
NC score	0.063297 (rank : 24)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

FMO1_HUMAN
NC score	0.062560 (rank : 25)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q01740, Q5QPT2, Q9UJC2	Gene names	FMO1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO5_HUMAN
NC score	0.054301 (rank : 26)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO3_HUMAN
NC score	0.053363 (rank : 27)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P31513, Q14854, Q8N5N5	Gene names	FMO3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3) (FMO form 2) (FMO II).

FMO4_HUMAN
NC score	0.052281 (rank : 28)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	P31512	Gene names	FMO4, FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

FMO2_HUMAN
NC score	0.051970 (rank : 29)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

FMO1_MOUSE
NC score	0.048219 (rank : 30)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	18	Shared Neighborhood Hits	15
SwissProt Accessions	P50285	Gene names	Fmo1, Fmo-1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO6_HUMAN
NC score	0.047161 (rank : 31)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	O60774	Gene names	FMO6
Domain Architecture
Description	Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6).

L2HDH_MOUSE
NC score	0.041786 (rank : 32)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YP0, Q3TH61, Q3U7Z0, Q3ULY6	Gene names	L2hgdh
Domain Architecture	No domain graphic available
Description	L-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.2) (Duranin).

L2HDH_HUMAN
NC score	0.040448 (rank : 33)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9P8, Q9BRR1	Gene names	L2HGDH, C14orf160
Domain Architecture	No domain graphic available
Description	L-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.2) (Duranin).

KMO_HUMAN
NC score	0.031100 (rank : 34)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	O15229, Q5SY07, Q5SY08, Q5SY09	Gene names	KMO
Domain Architecture	No domain graphic available
Description	Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase).

KMO_MOUSE
NC score	0.025876 (rank : 35)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WN4	Gene names	Kmo
Domain Architecture	No domain graphic available
Description	Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase).

TRXR1_HUMAN
NC score	0.024892 (rank : 36)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

ETFD_HUMAN
NC score	0.020963 (rank : 37)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q16134, Q7Z347	Gene names	ETFDH
Domain Architecture
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

RIMB1_HUMAN
NC score	0.014384 (rank : 38)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	1479	Shared Neighborhood Hits	3
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_MOUSE
NC score	0.011094 (rank : 39)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	1376	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).