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Network neighborhood for query Sequence : FMO3_HUMAN

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FMO3_HUMAN
SwissProt Accessions	P31513, Q14854, Q8N5N5	Gene names	FMO3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3) (FMO form 2) (FMO II).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FMO3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P31513, Q14854, Q8N5N5	Gene names	FMO3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3) (FMO form 2) (FMO II).

FMO3_MOUSE
θ value	0 (rank : 2)	NC score	0.999054 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

FMO6_HUMAN
θ value	0 (rank : 3)	NC score	0.998098 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	O60774	Gene names	FMO6
Domain Architecture
Description	Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6).

FMO2_MOUSE
θ value	5.9077e-185 (rank : 4)	NC score	0.995587 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

FMO2_HUMAN
θ value	3.24166e-183 (rank : 5)	NC score	0.995481 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

FMO1_HUMAN
θ value	1.845e-170 (rank : 6)	NC score	0.994629 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q01740, Q5QPT2, Q9UJC2	Gene names	FMO1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO1_MOUSE
θ value	4.11024e-170 (rank : 7)	NC score	0.994636 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	P50285	Gene names	Fmo1, Fmo-1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO5_MOUSE
θ value	3.60074e-166 (rank : 8)	NC score	0.992530 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	P97872	Gene names	Fmo5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO4_HUMAN
θ value	5.74867e-164 (rank : 9)	NC score	0.992468 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P31512	Gene names	FMO4, FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

FMO4_MOUSE
θ value	1.46527e-159 (rank : 10)	NC score	0.991569 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHG0	Gene names	Fmo4
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

FMO5_HUMAN
θ value	2.49938e-159 (rank : 11)	NC score	0.991653 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

SMOX_MOUSE
θ value	0.0736092 (rank : 12)	NC score	0.105802 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

OXLA_MOUSE
θ value	0.0961366 (rank : 13)	NC score	0.110896 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

SMOX_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.116121 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

LSD1_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.088277 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	455	Shared Neighborhood Hits	16
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.092906 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	224	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

AOF1_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.085147 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

NICA_MOUSE
θ value	1.06291 (rank : 18)	NC score	0.024301 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P57716, Q8VE20	Gene names	Ncstn
Domain Architecture
Description	Nicastrin precursor.

AOF1_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.066803 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

OXLA_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.089602 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

AOFB_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.053363 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	38	Shared Neighborhood Hits	16
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

Hits sorted by NC score

FMO3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	P31513, Q14854, Q8N5N5	Gene names	FMO3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3) (FMO form 2) (FMO II).

FMO3_MOUSE
NC score	0.999054 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

FMO6_HUMAN
NC score	0.998098 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	O60774	Gene names	FMO6
Domain Architecture
Description	Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6).

FMO2_MOUSE
NC score	0.995587 (rank : 4)	θ value	5.9077e-185 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

FMO2_HUMAN
NC score	0.995481 (rank : 5)	θ value	3.24166e-183 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

FMO1_MOUSE
NC score	0.994636 (rank : 6)	θ value	4.11024e-170 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	P50285	Gene names	Fmo1, Fmo-1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO1_HUMAN
NC score	0.994629 (rank : 7)	θ value	1.845e-170 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q01740, Q5QPT2, Q9UJC2	Gene names	FMO1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO5_MOUSE
NC score	0.992530 (rank : 8)	θ value	3.60074e-166 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	P97872	Gene names	Fmo5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO4_HUMAN
NC score	0.992468 (rank : 9)	θ value	5.74867e-164 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P31512	Gene names	FMO4, FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

FMO5_HUMAN
NC score	0.991653 (rank : 10)	θ value	2.49938e-159 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO4_MOUSE
NC score	0.991569 (rank : 11)	θ value	1.46527e-159 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHG0	Gene names	Fmo4
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

SMOX_HUMAN
NC score	0.116121 (rank : 12)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

OXLA_MOUSE
NC score	0.110896 (rank : 13)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

SMOX_MOUSE
NC score	0.105802 (rank : 14)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

LSD1_MOUSE
NC score	0.092906 (rank : 15)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	224	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

OXLA_HUMAN
NC score	0.089602 (rank : 16)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

LSD1_HUMAN
NC score	0.088277 (rank : 17)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	455	Shared Neighborhood Hits	16
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

AOF1_HUMAN
NC score	0.085147 (rank : 18)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
NC score	0.066803 (rank : 19)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOFB_HUMAN
NC score	0.053363 (rank : 20)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	38	Shared Neighborhood Hits	16
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

NICA_MOUSE
NC score	0.024301 (rank : 21)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P57716, Q8VE20	Gene names	Ncstn
Domain Architecture
Description	Nicastrin precursor.