Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : AOFA_MOUSE

For an explanation of this page, click here

AOFA_MOUSE
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AOFA_HUMAN
θ value	0 (rank : 1)	NC score	0.987545 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFA_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFB_HUMAN
θ value	0 (rank : 3)	NC score	0.989564 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFB_MOUSE
θ value	0 (rank : 4)	NC score	0.987861 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOF1_HUMAN
θ value	1.52774e-15 (rank : 5)	NC score	0.547626 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
θ value	1.68911e-14 (rank : 6)	NC score	0.543833 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

OXLA_MOUSE
θ value	4.30538e-10 (rank : 7)	NC score	0.499876 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

OXLA_HUMAN
θ value	7.34386e-10 (rank : 8)	NC score	0.470552 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

LSD1_HUMAN
θ value	9.59137e-10 (rank : 9)	NC score	0.403246 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	455	Shared Neighborhood Hits	18
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	2.79066e-09 (rank : 10)	NC score	0.420796 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	224	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

SMOX_HUMAN
θ value	0.00020696 (rank : 11)	NC score	0.330025 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

PAOX_MOUSE
θ value	0.00035302 (rank : 12)	NC score	0.415194 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

RETST_HUMAN
θ value	0.000786445 (rank : 13)	NC score	0.182123 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NUM9, Q53R95, Q53SA9, Q6UX05, Q8N2H5, Q96FA4, Q9NXE5	Gene names	RETSAT
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

SMOX_MOUSE
θ value	0.00175202 (rank : 14)	NC score	0.320009 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

RETST_MOUSE
θ value	0.00228821 (rank : 15)	NC score	0.173162 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

PPOX_HUMAN
θ value	0.00390308 (rank : 16)	NC score	0.259996 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	19
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

PAOX_HUMAN
θ value	0.0148317 (rank : 17)	NC score	0.333806 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

PCYOX_HUMAN
θ value	0.0330416 (rank : 18)	NC score	0.105419 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHG3, O94982, Q8N4N5, Q96QM8	Gene names	PCYOX1, KIAA0908, PCL1
Domain Architecture
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5) (PCL1).

PPOX_MOUSE
θ value	0.0330416 (rank : 19)	NC score	0.180940 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

CJ033_HUMAN
θ value	0.0736092 (rank : 20)	NC score	0.175553 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

CJ033_MOUSE
θ value	0.0736092 (rank : 21)	NC score	0.184408 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

TRXR1_MOUSE
θ value	0.125558 (rank : 22)	NC score	0.053479 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JMH6	Gene names	Txnrd1, Trxr1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic (EC 1.8.1.9) (TR) (TR1).

TRXR1_HUMAN
θ value	0.163984 (rank : 23)	NC score	0.058439 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

FMO5_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.024604 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

GSHR_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.047266 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P47791, Q7TNC2, Q8BN97, Q8C9Z6	Gene names	Gsr, Gr1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

L2HDH_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.042824 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9P8, Q9BRR1	Gene names	L2HGDH, C14orf160
Domain Architecture	No domain graphic available
Description	L-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.2) (Duranin).

L2HDH_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.043678 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YP0, Q3TH61, Q3U7Z0, Q3ULY6	Gene names	L2hgdh
Domain Architecture	No domain graphic available
Description	L-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.2) (Duranin).

AMID_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.021771 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BRQ8, Q63Z39	Gene names	AMID, PRG3
Domain Architecture	No domain graphic available
Description	Apoptosis-inducing factor-like mitochondrion-associated inducer of death (EC 1.-.-.-) (Apoptosis-inducing factor-homologous mitochondrion-associated inducer of death) (p53-responsive gene 3 protein).

DHSA_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.022939 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2B3, Q3UH25	Gene names	Sdha
Domain Architecture	No domain graphic available
Description	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor (EC 1.3.5.1) (Fp) (Flavoprotein subunit of complex II).

GSHR_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.043143 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	P00390, Q7Z5C9, Q9NP63	Gene names	GSR, GLUR, GRD1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

MAGAA_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.009919 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P43363	Gene names	MAGEA10, MAGE10
Domain Architecture
Description	Melanoma-associated antigen 10 (MAGE-10 antigen).

2ACA_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.011610 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

FMO3_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.048778 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

N4BP3_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.010151 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

AMID_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.019049 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUE4, Q8CHZ2	Gene names	Amid
Domain Architecture	No domain graphic available
Description	Apoptosis-inducing factor-like mitochondrion-associated inducer of death (EC 1.-.-.-) (Apoptosis-inducing factor-homologous mitochondrion-associated inducer of death).

DHSA_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.020541 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P31040, Q16395, Q9UMY5	Gene names	SDHA, SDH2, SDHF
Domain Architecture
Description	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor (EC 1.3.5.1) (Fp) (Flavoprotein subunit of complex II).

GSTT2_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.009289 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q61133, Q61134, Q64472	Gene names	Gstt2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).

PCYOX_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.151999 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

Hits sorted by NC score

AOFA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFB_HUMAN
NC score	0.989564 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFB_MOUSE
NC score	0.987861 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_HUMAN
NC score	0.987545 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOF1_HUMAN
NC score	0.547626 (rank : 5)	θ value	1.52774e-15 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
NC score	0.543833 (rank : 6)	θ value	1.68911e-14 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

OXLA_MOUSE
NC score	0.499876 (rank : 7)	θ value	4.30538e-10 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

OXLA_HUMAN
NC score	0.470552 (rank : 8)	θ value	7.34386e-10 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

LSD1_MOUSE
NC score	0.420796 (rank : 9)	θ value	2.79066e-09 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	224	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PAOX_MOUSE
NC score	0.415194 (rank : 10)	θ value	0.00035302 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

LSD1_HUMAN
NC score	0.403246 (rank : 11)	θ value	9.59137e-10 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	455	Shared Neighborhood Hits	18
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PAOX_HUMAN
NC score	0.333806 (rank : 12)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

SMOX_HUMAN
NC score	0.330025 (rank : 13)	θ value	0.00020696 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_MOUSE
NC score	0.320009 (rank : 14)	θ value	0.00175202 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

PPOX_HUMAN
NC score	0.259996 (rank : 15)	θ value	0.00390308 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	19
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

CJ033_MOUSE
NC score	0.184408 (rank : 16)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

RETST_HUMAN
NC score	0.182123 (rank : 17)	θ value	0.000786445 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NUM9, Q53R95, Q53SA9, Q6UX05, Q8N2H5, Q96FA4, Q9NXE5	Gene names	RETSAT
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

PPOX_MOUSE
NC score	0.180940 (rank : 18)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

CJ033_HUMAN
NC score	0.175553 (rank : 19)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

RETST_MOUSE
NC score	0.173162 (rank : 20)	θ value	0.00228821 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

PCYOX_MOUSE
NC score	0.151999 (rank : 21)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

PCYOX_HUMAN
NC score	0.105419 (rank : 22)	θ value	0.0330416 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHG3, O94982, Q8N4N5, Q96QM8	Gene names	PCYOX1, KIAA0908, PCL1
Domain Architecture
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5) (PCL1).

TRXR1_HUMAN
NC score	0.058439 (rank : 23)	θ value	0.163984 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

TRXR1_MOUSE
NC score	0.053479 (rank : 24)	θ value	0.125558 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JMH6	Gene names	Txnrd1, Trxr1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic (EC 1.8.1.9) (TR) (TR1).

FMO3_MOUSE
NC score	0.048778 (rank : 25)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

GSHR_MOUSE
NC score	0.047266 (rank : 26)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P47791, Q7TNC2, Q8BN97, Q8C9Z6	Gene names	Gsr, Gr1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

L2HDH_MOUSE
NC score	0.043678 (rank : 27)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YP0, Q3TH61, Q3U7Z0, Q3ULY6	Gene names	L2hgdh
Domain Architecture	No domain graphic available
Description	L-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.2) (Duranin).

GSHR_HUMAN
NC score	0.043143 (rank : 28)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	P00390, Q7Z5C9, Q9NP63	Gene names	GSR, GLUR, GRD1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

L2HDH_HUMAN
NC score	0.042824 (rank : 29)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9P8, Q9BRR1	Gene names	L2HGDH, C14orf160
Domain Architecture	No domain graphic available
Description	L-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.2) (Duranin).

FMO5_HUMAN
NC score	0.024604 (rank : 30)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

DHSA_MOUSE
NC score	0.022939 (rank : 31)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2B3, Q3UH25	Gene names	Sdha
Domain Architecture	No domain graphic available
Description	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor (EC 1.3.5.1) (Fp) (Flavoprotein subunit of complex II).

AMID_HUMAN
NC score	0.021771 (rank : 32)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BRQ8, Q63Z39	Gene names	AMID, PRG3
Domain Architecture	No domain graphic available
Description	Apoptosis-inducing factor-like mitochondrion-associated inducer of death (EC 1.-.-.-) (Apoptosis-inducing factor-homologous mitochondrion-associated inducer of death) (p53-responsive gene 3 protein).

DHSA_HUMAN
NC score	0.020541 (rank : 33)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P31040, Q16395, Q9UMY5	Gene names	SDHA, SDH2, SDHF
Domain Architecture
Description	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor (EC 1.3.5.1) (Fp) (Flavoprotein subunit of complex II).

AMID_MOUSE
NC score	0.019049 (rank : 34)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUE4, Q8CHZ2	Gene names	Amid
Domain Architecture	No domain graphic available
Description	Apoptosis-inducing factor-like mitochondrion-associated inducer of death (EC 1.-.-.-) (Apoptosis-inducing factor-homologous mitochondrion-associated inducer of death).

2ACA_HUMAN
NC score	0.011610 (rank : 35)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

N4BP3_HUMAN
NC score	0.010151 (rank : 36)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

MAGAA_HUMAN
NC score	0.009919 (rank : 37)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P43363	Gene names	MAGEA10, MAGE10
Domain Architecture
Description	Melanoma-associated antigen 10 (MAGE-10 antigen).

GSTT2_MOUSE
NC score	0.009289 (rank : 38)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q61133, Q61134, Q64472	Gene names	Gstt2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).