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Network neighborhood for query Sequence : CAC1F_MOUSE

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CAC1F_MOUSE
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1A_HUMAN
θ value	0 (rank : 1)	NC score	0.947368 (rank : 13)
Query Neighborhood Hits	142	Target Neighborhood Hits	387	Shared Neighborhood Hits	71
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	0 (rank : 2)	NC score	0.956113 (rank : 11)
Query Neighborhood Hits	142	Target Neighborhood Hits	267	Shared Neighborhood Hits	67
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
θ value	0 (rank : 3)	NC score	0.956259 (rank : 10)
Query Neighborhood Hits	142	Target Neighborhood Hits	257	Shared Neighborhood Hits	63
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	0 (rank : 4)	NC score	0.951216 (rank : 12)
Query Neighborhood Hits	142	Target Neighborhood Hits	351	Shared Neighborhood Hits	64
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_HUMAN
θ value	0 (rank : 5)	NC score	0.991921 (rank : 7)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
θ value	0 (rank : 6)	NC score	0.992222 (rank : 6)
Query Neighborhood Hits	142	Target Neighborhood Hits	130	Shared Neighborhood Hits	63
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
θ value	0 (rank : 7)	NC score	0.993541 (rank : 4)
Query Neighborhood Hits	142	Target Neighborhood Hits	118	Shared Neighborhood Hits	64
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1E_HUMAN
θ value	0 (rank : 8)	NC score	0.960357 (rank : 9)
Query Neighborhood Hits	142	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	0 (rank : 9)	NC score	0.960455 (rank : 8)
Query Neighborhood Hits	142	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1F_HUMAN
θ value	0 (rank : 10)	NC score	0.997447 (rank : 2)
Query Neighborhood Hits	142	Target Neighborhood Hits	141	Shared Neighborhood Hits	91
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	0 (rank : 11)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	142
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
θ value	0 (rank : 12)	NC score	0.993549 (rank : 3)
Query Neighborhood Hits	142	Target Neighborhood Hits	92	Shared Neighborhood Hits	58
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_MOUSE
θ value	0 (rank : 13)	NC score	0.993470 (rank : 5)
Query Neighborhood Hits	142	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SC11A_HUMAN
θ value	8.81223e-72 (rank : 14)	NC score	0.859051 (rank : 18)
Query Neighborhood Hits	142	Target Neighborhood Hits	111	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

CAC1I_HUMAN
θ value	1.96316e-71 (rank : 15)	NC score	0.896459 (rank : 14)
Query Neighborhood Hits	142	Target Neighborhood Hits	138	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

SCN9A_HUMAN
θ value	3.70236e-70 (rank : 16)	NC score	0.841119 (rank : 25)
Query Neighborhood Hits	142	Target Neighborhood Hits	157	Shared Neighborhood Hits	64
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN3A_HUMAN
θ value	6.31527e-70 (rank : 17)	NC score	0.843954 (rank : 23)
Query Neighborhood Hits	142	Target Neighborhood Hits	115	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN2A_HUMAN
θ value	4.09345e-69 (rank : 18)	NC score	0.840803 (rank : 26)
Query Neighborhood Hits	142	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN4A_HUMAN
θ value	5.34618e-69 (rank : 19)	NC score	0.851080 (rank : 21)
Query Neighborhood Hits	142	Target Neighborhood Hits	133	Shared Neighborhood Hits	65
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SC11A_MOUSE
θ value	4.52582e-68 (rank : 20)	NC score	0.860857 (rank : 17)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN8A_HUMAN
θ value	1.71981e-67 (rank : 21)	NC score	0.840606 (rank : 27)
Query Neighborhood Hits	142	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	6.53529e-67 (rank : 22)	NC score	0.837918 (rank : 30)
Query Neighborhood Hits	142	Target Neighborhood Hits	136	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN5A_HUMAN
θ value	6.11685e-65 (rank : 23)	NC score	0.853498 (rank : 19)
Query Neighborhood Hits	142	Target Neighborhood Hits	145	Shared Neighborhood Hits	65
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SC10A_MOUSE
θ value	7.98882e-65 (rank : 24)	NC score	0.843077 (rank : 24)
Query Neighborhood Hits	142	Target Neighborhood Hits	107	Shared Neighborhood Hits	62
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

CAC1H_MOUSE
θ value	8.83269e-64 (rank : 25)	NC score	0.870556 (rank : 15)
Query Neighborhood Hits	142	Target Neighborhood Hits	230	Shared Neighborhood Hits	65
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
θ value	1.15359e-63 (rank : 26)	NC score	0.867251 (rank : 16)
Query Neighborhood Hits	142	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC10A_HUMAN
θ value	1.15359e-63 (rank : 27)	NC score	0.838026 (rank : 29)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN1A_HUMAN
θ value	2.56992e-63 (rank : 28)	NC score	0.838548 (rank : 28)
Query Neighborhood Hits	142	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1G_HUMAN
θ value	9.76566e-63 (rank : 29)	NC score	0.852116 (rank : 20)
Query Neighborhood Hits	142	Target Neighborhood Hits	587	Shared Neighborhood Hits	68
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SCN7A_HUMAN
θ value	3.59435e-57 (rank : 30)	NC score	0.850362 (rank : 22)
Query Neighborhood Hits	142	Target Neighborhood Hits	135	Shared Neighborhood Hits	52
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

KCNF1_HUMAN
θ value	9.59137e-10 (rank : 31)	NC score	0.256640 (rank : 36)
Query Neighborhood Hits	142	Target Neighborhood Hits	109	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

PK2L2_HUMAN
θ value	1.25267e-09 (rank : 32)	NC score	0.395944 (rank : 31)
Query Neighborhood Hits	142	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_HUMAN
θ value	4.0297e-08 (rank : 33)	NC score	0.342516 (rank : 35)
Query Neighborhood Hits	142	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PK2L2_MOUSE
θ value	1.17247e-07 (rank : 34)	NC score	0.359244 (rank : 33)
Query Neighborhood Hits	142	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
θ value	5.81887e-07 (rank : 35)	NC score	0.348357 (rank : 34)
Query Neighborhood Hits	142	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PK2L1_HUMAN
θ value	4.92598e-06 (rank : 36)	NC score	0.361301 (rank : 32)
Query Neighborhood Hits	142	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

KCNV2_HUMAN
θ value	4.1701e-05 (rank : 37)	NC score	0.241838 (rank : 37)
Query Neighborhood Hits	142	Target Neighborhood Hits	137	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCND3_HUMAN
θ value	0.00175202 (rank : 38)	NC score	0.192273 (rank : 44)
Query Neighborhood Hits	142	Target Neighborhood Hits	162	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.00175202 (rank : 39)	NC score	0.192396 (rank : 43)
Query Neighborhood Hits	142	Target Neighborhood Hits	162	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNS3_HUMAN
θ value	0.00228821 (rank : 40)	NC score	0.188754 (rank : 45)
Query Neighborhood Hits	142	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND2_HUMAN
θ value	0.00509761 (rank : 41)	NC score	0.185972 (rank : 47)
Query Neighborhood Hits	142	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.00509761 (rank : 42)	NC score	0.186106 (rank : 46)
Query Neighborhood Hits	142	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNS2_HUMAN
θ value	0.00509761 (rank : 43)	NC score	0.211889 (rank : 40)
Query Neighborhood Hits	142	Target Neighborhood Hits	129	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
θ value	0.00509761 (rank : 44)	NC score	0.215527 (rank : 39)
Query Neighborhood Hits	142	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_HUMAN
θ value	0.0148317 (rank : 45)	NC score	0.208153 (rank : 42)
Query Neighborhood Hits	142	Target Neighborhood Hits	169	Shared Neighborhood Hits	58
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	0.0148317 (rank : 46)	NC score	0.208171 (rank : 41)
Query Neighborhood Hits	142	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB2_HUMAN
θ value	0.0148317 (rank : 47)	NC score	0.220991 (rank : 38)
Query Neighborhood Hits	142	Target Neighborhood Hits	212	Shared Neighborhood Hits	61
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNC3_HUMAN
θ value	0.0148317 (rank : 48)	NC score	0.131264 (rank : 56)
Query Neighborhood Hits	142	Target Neighborhood Hits	256	Shared Neighborhood Hits	53
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNS1_MOUSE
θ value	0.0148317 (rank : 49)	NC score	0.151545 (rank : 51)
Query Neighborhood Hits	142	Target Neighborhood Hits	114	Shared Neighborhood Hits	50
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC3_MOUSE
θ value	0.0193708 (rank : 50)	NC score	0.129875 (rank : 57)
Query Neighborhood Hits	142	Target Neighborhood Hits	173	Shared Neighborhood Hits	52
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCND1_HUMAN
θ value	0.0252991 (rank : 51)	NC score	0.171067 (rank : 49)
Query Neighborhood Hits	142	Target Neighborhood Hits	160	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS1_HUMAN
θ value	0.0252991 (rank : 52)	NC score	0.162472 (rank : 50)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	56
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCND1_MOUSE
θ value	0.0736092 (rank : 53)	NC score	0.174821 (rank : 48)
Query Neighborhood Hits	142	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

TIF1G_HUMAN
θ value	0.0736092 (rank : 54)	NC score	0.017277 (rank : 103)
Query Neighborhood Hits	142	Target Neighborhood Hits	410	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

KCNG3_MOUSE
θ value	0.0961366 (rank : 55)	NC score	0.118680 (rank : 60)
Query Neighborhood Hits	142	Target Neighborhood Hits	91	Shared Neighborhood Hits	44
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNC4_HUMAN
θ value	0.125558 (rank : 56)	NC score	0.141728 (rank : 54)
Query Neighborhood Hits	142	Target Neighborhood Hits	141	Shared Neighborhood Hits	52
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

FMN1A_MOUSE
θ value	0.163984 (rank : 57)	NC score	0.018309 (rank : 100)
Query Neighborhood Hits	142	Target Neighborhood Hits	423	Shared Neighborhood Hits	10
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

GP179_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.032404 (rank : 93)
Query Neighborhood Hits	142	Target Neighborhood Hits	372	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

KCNC4_MOUSE
θ value	0.21417 (rank : 59)	NC score	0.133513 (rank : 55)
Query Neighborhood Hits	142	Target Neighborhood Hits	130	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNG3_HUMAN
θ value	0.21417 (rank : 60)	NC score	0.119966 (rank : 59)
Query Neighborhood Hits	142	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

SFPQ_MOUSE
θ value	0.21417 (rank : 61)	NC score	0.022035 (rank : 96)
Query Neighborhood Hits	142	Target Neighborhood Hits	958	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

XRCC1_MOUSE
θ value	0.21417 (rank : 62)	NC score	0.031068 (rank : 94)
Query Neighborhood Hits	142	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

CSTFT_MOUSE
θ value	0.279714 (rank : 63)	NC score	0.016244 (rank : 105)
Query Neighborhood Hits	142	Target Neighborhood Hits	356	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

KCNQ4_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.094774 (rank : 62)
Query Neighborhood Hits	142	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

BSPRY_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.016684 (rank : 104)
Query Neighborhood Hits	142	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

AMPH_HUMAN
θ value	0.62314 (rank : 66)	NC score	0.010763 (rank : 111)
Query Neighborhood Hits	142	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

CGRE1_MOUSE
θ value	0.62314 (rank : 67)	NC score	0.021243 (rank : 97)
Query Neighborhood Hits	142	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

DNL3_HUMAN
θ value	0.62314 (rank : 68)	NC score	0.036624 (rank : 91)
Query Neighborhood Hits	142	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

KCNC1_HUMAN
θ value	0.62314 (rank : 69)	NC score	0.146097 (rank : 52)
Query Neighborhood Hits	142	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
θ value	0.62314 (rank : 70)	NC score	0.144349 (rank : 53)
Query Neighborhood Hits	142	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

SNPC1_MOUSE
θ value	0.62314 (rank : 71)	NC score	0.018873 (rank : 99)
Query Neighborhood Hits	142	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0S9	Gene names	Snapc1
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (snRNA- activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) (Small nuclear RNA-activating complex polypeptide 1).

ANR21_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.005052 (rank : 141)
Query Neighborhood Hits	142	Target Neighborhood Hits	864	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

DNL3_MOUSE
θ value	0.813845 (rank : 73)	NC score	0.033594 (rank : 92)
Query Neighborhood Hits	142	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

PKDRE_HUMAN
θ value	0.813845 (rank : 74)	NC score	0.107784 (rank : 61)
Query Neighborhood Hits	142	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

POT15_HUMAN
θ value	0.813845 (rank : 75)	NC score	0.004965 (rank : 144)
Query Neighborhood Hits	142	Target Neighborhood Hits	893	Shared Neighborhood Hits	10
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

BARX2_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.001343 (rank : 154)
Query Neighborhood Hits	142	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UMQ3, O43518	Gene names	BARX2
Domain Architecture
Description	Homeobox protein BarH-like 2.

CO2A1_HUMAN
θ value	1.06291 (rank : 77)	NC score	0.009270 (rank : 115)
Query Neighborhood Hits	142	Target Neighborhood Hits	486	Shared Neighborhood Hits	14
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

DJBP_MOUSE
θ value	1.06291 (rank : 78)	NC score	0.055643 (rank : 88)
Query Neighborhood Hits	142	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

KCNQ5_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.071627 (rank : 79)
Query Neighborhood Hits	142	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

TP53B_HUMAN
θ value	1.06291 (rank : 80)	NC score	0.017505 (rank : 101)
Query Neighborhood Hits	142	Target Neighborhood Hits	413	Shared Neighborhood Hits	11
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

VIPR2_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.005902 (rank : 135)
Query Neighborhood Hits	142	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

AHR_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.007587 (rank : 122)
Query Neighborhood Hits	142	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

IF2P_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.010344 (rank : 113)
Query Neighborhood Hits	142	Target Neighborhood Hits	889	Shared Neighborhood Hits	21
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CELR2_HUMAN
θ value	1.81305 (rank : 84)	NC score	-0.001780 (rank : 162)
Query Neighborhood Hits	142	Target Neighborhood Hits	657	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

LAD1_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.008337 (rank : 119)
Query Neighborhood Hits	142	Target Neighborhood Hits	391	Shared Neighborhood Hits	9
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

RAGE_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.005992 (rank : 132)
Query Neighborhood Hits	142	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

ACM1_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.000729 (rank : 156)
Query Neighborhood Hits	142	Target Neighborhood Hits	908	Shared Neighborhood Hits	7
SwissProt Accessions	P11229	Gene names	CHRM1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

FAN_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.001760 (rank : 152)
Query Neighborhood Hits	142	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

GCNL2_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.014318 (rank : 108)
Query Neighborhood Hits	142	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

TEX14_HUMAN
θ value	2.36792 (rank : 90)	NC score	-0.001037 (rank : 160)
Query Neighborhood Hits	142	Target Neighborhood Hits	1103	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ZN263_HUMAN
θ value	2.36792 (rank : 91)	NC score	-0.004712 (rank : 165)
Query Neighborhood Hits	142	Target Neighborhood Hits	795	Shared Neighborhood Hits	4
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).

ACM1_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.001311 (rank : 155)
Query Neighborhood Hits	142	Target Neighborhood Hits	917	Shared Neighborhood Hits	7
SwissProt Accessions	P12657, Q8BJN3	Gene names	Chrm1, Chrm-1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

ERIC1_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.007191 (rank : 127)
Query Neighborhood Hits	142	Target Neighborhood Hits	364	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

GRHL1_MOUSE
θ value	3.0926 (rank : 94)	NC score	0.005494 (rank : 139)
Query Neighborhood Hits	142	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q921D9, Q8K5C1	Gene names	Grhl1, Mgr, Tcfcp2l2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32).

MMP9_MOUSE
θ value	3.0926 (rank : 95)	NC score	0.002650 (rank : 150)
Query Neighborhood Hits	142	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

OSBP1_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.005513 (rank : 138)
Query Neighborhood Hits	142	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

RGS3_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.014557 (rank : 107)
Query Neighborhood Hits	142	Target Neighborhood Hits	1621	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SFPQ_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.017492 (rank : 102)
Query Neighborhood Hits	142	Target Neighborhood Hits	986	Shared Neighborhood Hits	19
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SMCA4_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.006772 (rank : 128)
Query Neighborhood Hits	142	Target Neighborhood Hits	597	Shared Neighborhood Hits	15
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

TPTE_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.089204 (rank : 65)
Query Neighborhood Hits	142	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

VIPR2_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.008244 (rank : 121)
Query Neighborhood Hits	142	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

ZNF24_HUMAN
θ value	3.0926 (rank : 102)	NC score	-0.004533 (rank : 164)
Query Neighborhood Hits	142	Target Neighborhood Hits	716	Shared Neighborhood Hits	3
SwissProt Accessions	P17028, O14754	Gene names	ZNF24, KOX17, ZNF191, ZSCAN3
Domain Architecture
Description	Zinc finger protein 24 (Zinc finger protein 191) (Zinc finger protein KOX17) (Retinoic acid suppression protein A) (RSG-A) (Zinc finger and SCAN domain-containing protein 3).

ACTN2_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.009579 (rank : 114)
Query Neighborhood Hits	142	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

DLG3_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.000273 (rank : 157)
Query Neighborhood Hits	142	Target Neighborhood Hits	269	Shared Neighborhood Hits	3
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

GLE1_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.004580 (rank : 146)
Query Neighborhood Hits	142	Target Neighborhood Hits	445	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

K0323_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.011047 (rank : 109)
Query Neighborhood Hits	142	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U38, Q8BGJ6, Q8C082	Gene names	Kiaa0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

MAP4_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.010936 (rank : 110)
Query Neighborhood Hits	142	Target Neighborhood Hits	428	Shared Neighborhood Hits	10
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MCLN3_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.038428 (rank : 90)
Query Neighborhood Hits	142	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4F0, Q8BS73, Q8BSG1, Q8CDB2	Gene names	Mcoln3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

TCAL5_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.010526 (rank : 112)
Query Neighborhood Hits	142	Target Neighborhood Hits	806	Shared Neighborhood Hits	19
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ACM5_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.001444 (rank : 153)
Query Neighborhood Hits	142	Target Neighborhood Hits	878	Shared Neighborhood Hits	7
SwissProt Accessions	P08912, Q96RG7	Gene names	CHRM5
Domain Architecture
Description	Muscarinic acetylcholine receptor M5.

ACTN3_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.006656 (rank : 129)
Query Neighborhood Hits	142	Target Neighborhood Hits	272	Shared Neighborhood Hits	9
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.006624 (rank : 130)
Query Neighborhood Hits	142	Target Neighborhood Hits	265	Shared Neighborhood Hits	9
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

BAZ2A_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.005045 (rank : 142)
Query Neighborhood Hits	142	Target Neighborhood Hits	780	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

DACH1_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.007331 (rank : 125)
Query Neighborhood Hits	142	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DACH1_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.007436 (rank : 124)
Query Neighborhood Hits	142	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

HDGF_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.007501 (rank : 123)
Query Neighborhood Hits	142	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

IWS1_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.027672 (rank : 95)
Query Neighborhood Hits	142	Target Neighborhood Hits	1258	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYCB2_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.004496 (rank : 147)
Query Neighborhood Hits	142	Target Neighborhood Hits	390	Shared Neighborhood Hits	8
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

WBP4_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.008314 (rank : 120)
Query Neighborhood Hits	142	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

5NT1B_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.005704 (rank : 136)
Query Neighborhood Hits	142	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

ACTN2_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.008482 (rank : 118)
Query Neighborhood Hits	142	Target Neighborhood Hits	287	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

BICD2_MOUSE
θ value	6.88961 (rank : 122)	NC score	-0.001276 (rank : 161)
Query Neighborhood Hits	142	Target Neighborhood Hits	864	Shared Neighborhood Hits	10
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CHD3_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.001968 (rank : 151)
Query Neighborhood Hits	142	Target Neighborhood Hits	397	Shared Neighborhood Hits	11
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

DIPA_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.015289 (rank : 106)
Query Neighborhood Hits	142	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q15834, Q96HA0	Gene names	CCDC85B, DIPA
Domain Architecture	No domain graphic available
Description	Delta-interacting protein A (Hepatitis delta antigen-interacting protein A) (Coiled-coil domain-containing protein 85B).

FLNB_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.005123 (rank : 140)
Query Neighborhood Hits	142	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

GASR_HUMAN
θ value	6.88961 (rank : 126)	NC score	-0.003649 (rank : 163)
Query Neighborhood Hits	142	Target Neighborhood Hits	874	Shared Neighborhood Hits	5
SwissProt Accessions	P32239	Gene names	CCKBR, CCKRB
Domain Architecture
Description	Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R).

HXD9_MOUSE
θ value	6.88961 (rank : 127)	NC score	-0.001026 (rank : 159)
Query Neighborhood Hits	142	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	P28357, Q3UYS2	Gene names	Hoxd9, Hox-4.4, Hoxd-9
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4.4) (Hox-5.2).

KCNQ2_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.066277 (rank : 83)
Query Neighborhood Hits	142	Target Neighborhood Hits	114	Shared Neighborhood Hits	32
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

MAP1A_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.008890 (rank : 116)
Query Neighborhood Hits	142	Target Neighborhood Hits	1626	Shared Neighborhood Hits	32
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NCKX3_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.003416 (rank : 148)
Query Neighborhood Hits	142	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC58, Q9BQJ9, Q9BQL7, Q9BQY3, Q9H519	Gene names	SLC24A3, NCKX3
Domain Architecture
Description	Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).

PLDN_MOUSE
θ value	6.88961 (rank : 131)	NC score	0.008497 (rank : 117)
Query Neighborhood Hits	142	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0C0, Q3TUT4, Q91VG4	Gene names	Pldn, P2, Pa
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein) (Syntaxin 13-interacting protein).

BCLF1_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.002998 (rank : 149)
Query Neighborhood Hits	142	Target Neighborhood Hits	298	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

BSN_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.019409 (rank : 98)
Query Neighborhood Hits	142	Target Neighborhood Hits	2057	Shared Neighborhood Hits	41
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CECR6_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.005943 (rank : 134)
Query Neighborhood Hits	142	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXQ6	Gene names	CECR6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6.

CEP68_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.004725 (rank : 145)
Query Neighborhood Hits	142	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CO2A1_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.006428 (rank : 131)
Query Neighborhood Hits	142	Target Neighborhood Hits	483	Shared Neighborhood Hits	13
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CSTFT_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.005961 (rank : 133)
Query Neighborhood Hits	142	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

E41L2_MOUSE
θ value	8.99809 (rank : 138)	NC score	-0.000133 (rank : 158)
Query Neighborhood Hits	142	Target Neighborhood Hits	459	Shared Neighborhood Hits	7
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

IPP2_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.005557 (rank : 137)
Query Neighborhood Hits	142	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

OSBP2_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.005007 (rank : 143)
Query Neighborhood Hits	142	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

PARP1_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.007271 (rank : 126)
Query Neighborhood Hits	142	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

TPTE2_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.127509 (rank : 58)
Query Neighborhood Hits	142	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNA1_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.090618 (rank : 64)
Query Neighborhood Hits	142	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.092639 (rank : 63)
Query Neighborhood Hits	142	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA2_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.088170 (rank : 68)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.089156 (rank : 66)
Query Neighborhood Hits	142	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA3_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.077637 (rank : 75)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.076723 (rank : 77)
Query Neighborhood Hits	142	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.067520 (rank : 82)
Query Neighborhood Hits	142	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.067844 (rank : 81)
Query Neighborhood Hits	142	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.074868 (rank : 78)
Query Neighborhood Hits	142	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.079599 (rank : 73)
Query Neighborhood Hits	142	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.082289 (rank : 71)
Query Neighborhood Hits	142	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.088609 (rank : 67)
Query Neighborhood Hits	142	Target Neighborhood Hits	106	Shared Neighborhood Hits	40
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNG1_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.086380 (rank : 69)
Query Neighborhood Hits	142	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.083642 (rank : 70)
Query Neighborhood Hits	142	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG4_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.077369 (rank : 76)
Query Neighborhood Hits	142	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.069524 (rank : 80)
Query Neighborhood Hits	142	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.082128 (rank : 72)
Query Neighborhood Hits	142	Target Neighborhood Hits	175	Shared Neighborhood Hits	41
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.061998 (rank : 85)
Query Neighborhood Hits	142	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.060693 (rank : 86)
Query Neighborhood Hits	142	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.059578 (rank : 87)
Query Neighborhood Hits	142	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MCLN2_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.064396 (rank : 84)
Query Neighborhood Hits	142	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

PKDRE_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.078926 (rank : 74)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TRPV3_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.051896 (rank : 89)
Query Neighborhood Hits	142	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

Hits sorted by NC score

CAC1F_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 11)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	142
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.997447 (rank : 2)	θ value	0 (rank : 10)
Query Neighborhood Hits	142	Target Neighborhood Hits	141	Shared Neighborhood Hits	91
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
NC score	0.993549 (rank : 3)	θ value	0 (rank : 12)
Query Neighborhood Hits	142	Target Neighborhood Hits	92	Shared Neighborhood Hits	58
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1D_HUMAN
NC score	0.993541 (rank : 4)	θ value	0 (rank : 7)
Query Neighborhood Hits	142	Target Neighborhood Hits	118	Shared Neighborhood Hits	64
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1S_MOUSE
NC score	0.993470 (rank : 5)	θ value	0 (rank : 13)
Query Neighborhood Hits	142	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1C_MOUSE
NC score	0.992222 (rank : 6)	θ value	0 (rank : 6)
Query Neighborhood Hits	142	Target Neighborhood Hits	130	Shared Neighborhood Hits	63
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
NC score	0.991921 (rank : 7)	θ value	0 (rank : 5)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1E_MOUSE
NC score	0.960455 (rank : 8)	θ value	0 (rank : 9)
Query Neighborhood Hits	142	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.960357 (rank : 9)	θ value	0 (rank : 8)
Query Neighborhood Hits	142	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1B_HUMAN
NC score	0.956259 (rank : 10)	θ value	0 (rank : 3)
Query Neighborhood Hits	142	Target Neighborhood Hits	257	Shared Neighborhood Hits	63
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_MOUSE
NC score	0.956113 (rank : 11)	θ value	0 (rank : 2)
Query Neighborhood Hits	142	Target Neighborhood Hits	267	Shared Neighborhood Hits	67
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_MOUSE
NC score	0.951216 (rank : 12)	θ value	0 (rank : 4)
Query Neighborhood Hits	142	Target Neighborhood Hits	351	Shared Neighborhood Hits	64
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_HUMAN
NC score	0.947368 (rank : 13)	θ value	0 (rank : 1)
Query Neighborhood Hits	142	Target Neighborhood Hits	387	Shared Neighborhood Hits	71
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1I_HUMAN
NC score	0.896459 (rank : 14)	θ value	1.96316e-71 (rank : 15)
Query Neighborhood Hits	142	Target Neighborhood Hits	138	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.870556 (rank : 15)	θ value	8.83269e-64 (rank : 25)
Query Neighborhood Hits	142	Target Neighborhood Hits	230	Shared Neighborhood Hits	65
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.867251 (rank : 16)	θ value	1.15359e-63 (rank : 26)
Query Neighborhood Hits	142	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC11A_MOUSE
NC score	0.860857 (rank : 17)	θ value	4.52582e-68 (rank : 20)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC11A_HUMAN
NC score	0.859051 (rank : 18)	θ value	8.81223e-72 (rank : 14)
Query Neighborhood Hits	142	Target Neighborhood Hits	111	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN5A_HUMAN
NC score	0.853498 (rank : 19)	θ value	6.11685e-65 (rank : 23)
Query Neighborhood Hits	142	Target Neighborhood Hits	145	Shared Neighborhood Hits	65
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1G_HUMAN
NC score	0.852116 (rank : 20)	θ value	9.76566e-63 (rank : 29)
Query Neighborhood Hits	142	Target Neighborhood Hits	587	Shared Neighborhood Hits	68
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SCN4A_HUMAN
NC score	0.851080 (rank : 21)	θ value	5.34618e-69 (rank : 19)
Query Neighborhood Hits	142	Target Neighborhood Hits	133	Shared Neighborhood Hits	65
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN7A_HUMAN
NC score	0.850362 (rank : 22)	θ value	3.59435e-57 (rank : 30)
Query Neighborhood Hits	142	Target Neighborhood Hits	135	Shared Neighborhood Hits	52
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN3A_HUMAN
NC score	0.843954 (rank : 23)	θ value	6.31527e-70 (rank : 17)
Query Neighborhood Hits	142	Target Neighborhood Hits	115	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SC10A_MOUSE
NC score	0.843077 (rank : 24)	θ value	7.98882e-65 (rank : 24)
Query Neighborhood Hits	142	Target Neighborhood Hits	107	Shared Neighborhood Hits	62
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN9A_HUMAN
NC score	0.841119 (rank : 25)	θ value	3.70236e-70 (rank : 16)
Query Neighborhood Hits	142	Target Neighborhood Hits	157	Shared Neighborhood Hits	64
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN2A_HUMAN
NC score	0.840803 (rank : 26)	θ value	4.09345e-69 (rank : 18)
Query Neighborhood Hits	142	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN8A_HUMAN
NC score	0.840606 (rank : 27)	θ value	1.71981e-67 (rank : 21)
Query Neighborhood Hits	142	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN1A_HUMAN
NC score	0.838548 (rank : 28)	θ value	2.56992e-63 (rank : 28)
Query Neighborhood Hits	142	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SC10A_HUMAN
NC score	0.838026 (rank : 29)	θ value	1.15359e-63 (rank : 27)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN8A_MOUSE
NC score	0.837918 (rank : 30)	θ value	6.53529e-67 (rank : 22)
Query Neighborhood Hits	142	Target Neighborhood Hits	136	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

PK2L2_HUMAN
NC score	0.395944 (rank : 31)	θ value	1.25267e-09 (rank : 32)
Query Neighborhood Hits	142	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.361301 (rank : 32)	θ value	4.92598e-06 (rank : 36)
Query Neighborhood Hits	142	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.359244 (rank : 33)	θ value	1.17247e-07 (rank : 34)
Query Neighborhood Hits	142	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.348357 (rank : 34)	θ value	5.81887e-07 (rank : 35)
Query Neighborhood Hits	142	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.342516 (rank : 35)	θ value	4.0297e-08 (rank : 33)
Query Neighborhood Hits	142	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNF1_HUMAN
NC score	0.256640 (rank : 36)	θ value	9.59137e-10 (rank : 31)
Query Neighborhood Hits	142	Target Neighborhood Hits	109	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
NC score	0.241838 (rank : 37)	θ value	4.1701e-05 (rank : 37)
Query Neighborhood Hits	142	Target Neighborhood Hits	137	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
NC score	0.220991 (rank : 38)	θ value	0.0148317 (rank : 47)
Query Neighborhood Hits	142	Target Neighborhood Hits	212	Shared Neighborhood Hits	61
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.215527 (rank : 39)	θ value	0.00509761 (rank : 44)
Query Neighborhood Hits	142	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.211889 (rank : 40)	θ value	0.00509761 (rank : 43)
Query Neighborhood Hits	142	Target Neighborhood Hits	129	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_MOUSE
NC score	0.208171 (rank : 41)	θ value	0.0148317 (rank : 46)
Query Neighborhood Hits	142	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.208153 (rank : 42)	θ value	0.0148317 (rank : 45)
Query Neighborhood Hits	142	Target Neighborhood Hits	169	Shared Neighborhood Hits	58
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCND3_MOUSE
NC score	0.192396 (rank : 43)	θ value	0.00175202 (rank : 39)
Query Neighborhood Hits	142	Target Neighborhood Hits	162	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.192273 (rank : 44)	θ value	0.00175202 (rank : 38)
Query Neighborhood Hits	142	Target Neighborhood Hits	162	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNS3_HUMAN
NC score	0.188754 (rank : 45)	θ value	0.00228821 (rank : 40)
Query Neighborhood Hits	142	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND2_MOUSE
NC score	0.186106 (rank : 46)	θ value	0.00509761 (rank : 42)
Query Neighborhood Hits	142	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.185972 (rank : 47)	θ value	0.00509761 (rank : 41)
Query Neighborhood Hits	142	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND1_MOUSE
NC score	0.174821 (rank : 48)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	142	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.171067 (rank : 49)	θ value	0.0252991 (rank : 51)
Query Neighborhood Hits	142	Target Neighborhood Hits	160	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS1_HUMAN
NC score	0.162472 (rank : 50)	θ value	0.0252991 (rank : 52)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	56
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNS1_MOUSE
NC score	0.151545 (rank : 51)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	142	Target Neighborhood Hits	114	Shared Neighborhood Hits	50
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_HUMAN
NC score	0.146097 (rank : 52)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	142	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.144349 (rank : 53)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	142	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.141728 (rank : 54)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	142	Target Neighborhood Hits	141	Shared Neighborhood Hits	52
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
NC score	0.133513 (rank : 55)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	142	Target Neighborhood Hits	130	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_HUMAN
NC score	0.131264 (rank : 56)	θ value	0.0148317 (rank : 48)
Query Neighborhood Hits	142	Target Neighborhood Hits	256	Shared Neighborhood Hits	53
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.129875 (rank : 57)	θ value	0.0193708 (rank : 50)
Query Neighborhood Hits	142	Target Neighborhood Hits	173	Shared Neighborhood Hits	52
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

TPTE2_HUMAN
NC score	0.127509 (rank : 58)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	142	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNG3_HUMAN
NC score	0.119966 (rank : 59)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	142	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
NC score	0.118680 (rank : 60)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	142	Target Neighborhood Hits	91	Shared Neighborhood Hits	44
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

PKDRE_HUMAN
NC score	0.107784 (rank : 61)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	142	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNQ4_HUMAN
NC score	0.094774 (rank : 62)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	142	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNA1_MOUSE
NC score	0.092639 (rank : 63)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	142	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.090618 (rank : 64)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	142	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

TPTE_HUMAN
NC score	0.089204 (rank : 65)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	142	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNA2_MOUSE
NC score	0.089156 (rank : 66)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	142	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA6_MOUSE
NC score	0.088609 (rank : 67)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	142	Target Neighborhood Hits	106	Shared Neighborhood Hits	40
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA2_HUMAN
NC score	0.088170 (rank : 68)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNG1_HUMAN
NC score	0.086380 (rank : 69)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	142	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
NC score	0.083642 (rank : 70)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	142	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNA6_HUMAN
NC score	0.082289 (rank : 71)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	142	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNQ1_MOUSE
NC score	0.082128 (rank : 72)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	142	Target Neighborhood Hits	175	Shared Neighborhood Hits	41
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA5_MOUSE
NC score	0.079599 (rank : 73)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	142	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

PKDRE_MOUSE
NC score	0.078926 (rank : 74)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNA3_HUMAN
NC score	0.077637 (rank : 75)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNG4_HUMAN
NC score	0.077369 (rank : 76)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	142	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNA3_MOUSE
NC score	0.076723 (rank : 77)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	142	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA5_HUMAN
NC score	0.074868 (rank : 78)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	142	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNQ5_HUMAN
NC score	0.071627 (rank : 79)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	142	Target Neighborhood Hits	163	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ1_HUMAN
NC score	0.069524 (rank : 80)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	142	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA4_MOUSE
NC score	0.067844 (rank : 81)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	142	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.067520 (rank : 82)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	142	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ2_HUMAN
NC score	0.066277 (rank : 83)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	142	Target Neighborhood Hits	114	Shared Neighborhood Hits	32
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

MCLN2_MOUSE
NC score	0.064396 (rank : 84)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	142	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

KCNQ2_MOUSE
NC score	0.061998 (rank : 85)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	142	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
NC score	0.060693 (rank : 86)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	142	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
NC score	0.059578 (rank : 87)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	142	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

DJBP_MOUSE
NC score	0.055643 (rank : 88)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	142	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

TRPV3_HUMAN
NC score	0.051896 (rank : 89)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	142	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

MCLN3_MOUSE
NC score	0.038428 (rank : 90)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	142	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4F0, Q8BS73, Q8BSG1, Q8CDB2	Gene names	Mcoln3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

DNL3_HUMAN
NC score	0.036624 (rank : 91)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	142	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
NC score	0.033594 (rank : 92)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	142	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

GP179_HUMAN
NC score	0.032404 (rank : 93)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	142	Target Neighborhood Hits	372	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

XRCC1_MOUSE
NC score	0.031068 (rank : 94)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	142	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

IWS1_MOUSE
NC score	0.027672 (rank : 95)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	142	Target Neighborhood Hits	1258	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SFPQ_MOUSE
NC score	0.022035 (rank : 96)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	142	Target Neighborhood Hits	958	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CGRE1_MOUSE
NC score	0.021243 (rank : 97)	θ value	0.62314 (rank : 67)
Query Neighborhood Hits	142	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

BSN_MOUSE
NC score	0.019409 (rank : 98)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	142	Target Neighborhood Hits	2057	Shared Neighborhood Hits	41
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SNPC1_MOUSE
NC score	0.018873 (rank : 99)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	142	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0S9	Gene names	Snapc1
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (snRNA- activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) (Small nuclear RNA-activating complex polypeptide 1).

FMN1A_MOUSE
NC score	0.018309 (rank : 100)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	142	Target Neighborhood Hits	423	Shared Neighborhood Hits	10
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

TP53B_HUMAN
NC score	0.017505 (rank : 101)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	142	Target Neighborhood Hits	413	Shared Neighborhood Hits	11
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SFPQ_HUMAN
NC score	0.017492 (rank : 102)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	142	Target Neighborhood Hits	986	Shared Neighborhood Hits	19
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TIF1G_HUMAN
NC score	0.017277 (rank : 103)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	142	Target Neighborhood Hits	410	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

BSPRY_MOUSE
NC score	0.016684 (rank : 104)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	142	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

CSTFT_MOUSE
NC score	0.016244 (rank : 105)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	142	Target Neighborhood Hits	356	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

DIPA_HUMAN
NC score	0.015289 (rank : 106)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	142	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q15834, Q96HA0	Gene names	CCDC85B, DIPA
Domain Architecture	No domain graphic available
Description	Delta-interacting protein A (Hepatitis delta antigen-interacting protein A) (Coiled-coil domain-containing protein 85B).

RGS3_MOUSE
NC score	0.014557 (rank : 107)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	142	Target Neighborhood Hits	1621	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

GCNL2_MOUSE
NC score	0.014318 (rank : 108)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	142	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

K0323_MOUSE
NC score	0.011047 (rank : 109)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	142	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U38, Q8BGJ6, Q8C082	Gene names	Kiaa0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

MAP4_HUMAN
NC score	0.010936 (rank : 110)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	142	Target Neighborhood Hits	428	Shared Neighborhood Hits	10
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

AMPH_HUMAN
NC score	0.010763 (rank : 111)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	142	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

TCAL5_HUMAN
NC score	0.010526 (rank : 112)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	142	Target Neighborhood Hits	806	Shared Neighborhood Hits	19
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

IF2P_HUMAN
NC score	0.010344 (rank : 113)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	142	Target Neighborhood Hits	889	Shared Neighborhood Hits	21
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

ACTN2_HUMAN
NC score	0.009579 (rank : 114)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	142	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

CO2A1_HUMAN
NC score	0.009270 (rank : 115)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	142	Target Neighborhood Hits	486	Shared Neighborhood Hits	14
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

MAP1A_HUMAN
NC score	0.008890 (rank : 116)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	142	Target Neighborhood Hits	1626	Shared Neighborhood Hits	32
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PLDN_MOUSE
NC score	0.008497 (rank : 117)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	142	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0C0, Q3TUT4, Q91VG4	Gene names	Pldn, P2, Pa
Domain Architecture	No domain graphic available
Description	Pallidin (Pallid protein) (Syntaxin 13-interacting protein).

ACTN2_MOUSE
NC score	0.008482 (rank : 118)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	142	Target Neighborhood Hits	287	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

LAD1_MOUSE
NC score	0.008337 (rank : 119)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	142	Target Neighborhood Hits	391	Shared Neighborhood Hits	9
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

WBP4_MOUSE
NC score	0.008314 (rank : 120)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	142	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

VIPR2_MOUSE
NC score	0.008244 (rank : 121)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	142	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

AHR_MOUSE
NC score	0.007587 (rank : 122)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	142	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

HDGF_MOUSE
NC score	0.007501 (rank : 123)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	142	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

DACH1_MOUSE
NC score	0.007436 (rank : 124)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	142	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DACH1_HUMAN
NC score	0.007331 (rank : 125)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	142	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

PARP1_MOUSE
NC score	0.007271 (rank : 126)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	142	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

ERIC1_HUMAN
NC score	0.007191 (rank : 127)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	142	Target Neighborhood Hits	364	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

SMCA4_HUMAN
NC score	0.006772 (rank : 128)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	142	Target Neighborhood Hits	597	Shared Neighborhood Hits	15
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

ACTN3_HUMAN
NC score	0.006656 (rank : 129)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	142	Target Neighborhood Hits	272	Shared Neighborhood Hits	9
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
NC score	0.006624 (rank : 130)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	142	Target Neighborhood Hits	265	Shared Neighborhood Hits	9
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

CO2A1_MOUSE
NC score	0.006428 (rank : 131)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	142	Target Neighborhood Hits	483	Shared Neighborhood Hits	13
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

RAGE_MOUSE
NC score	0.005992 (rank : 132)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	142	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

CSTFT_HUMAN
NC score	0.005961 (rank : 133)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	142	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

CECR6_HUMAN
NC score	0.005943 (rank : 134)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	142	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXQ6	Gene names	CECR6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6.

VIPR2_HUMAN
NC score	0.005902 (rank : 135)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	142	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

5NT1B_HUMAN
NC score	0.005704 (rank : 136)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	142	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

IPP2_MOUSE
NC score	0.005557 (rank : 137)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	142	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

OSBP1_HUMAN
NC score	0.005513 (rank : 138)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	142	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

GRHL1_MOUSE
NC score	0.005494 (rank : 139)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	142	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q921D9, Q8K5C1	Gene names	Grhl1, Mgr, Tcfcp2l2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32).

FLNB_HUMAN
NC score	0.005123 (rank : 140)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	142	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

ANR21_HUMAN
NC score	0.005052 (rank : 141)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	142	Target Neighborhood Hits	864	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

BAZ2A_HUMAN
NC score	0.005045 (rank : 142)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	142	Target Neighborhood Hits	780	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

OSBP2_HUMAN
NC score	0.005007 (rank : 143)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	142	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

POT15_HUMAN
NC score	0.004965 (rank : 144)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	142	Target Neighborhood Hits	893	Shared Neighborhood Hits	10
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

CEP68_HUMAN
NC score	0.004725 (rank : 145)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	142	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

GLE1_HUMAN
NC score	0.004580 (rank : 146)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	142	Target Neighborhood Hits	445	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

MYCB2_HUMAN
NC score	0.004496 (rank : 147)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	142	Target Neighborhood Hits	390	Shared Neighborhood Hits	8
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NCKX3_HUMAN
NC score	0.003416 (rank : 148)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	142	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC58, Q9BQJ9, Q9BQL7, Q9BQY3, Q9H519	Gene names	SLC24A3, NCKX3
Domain Architecture
Description	Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).

BCLF1_HUMAN
NC score	0.002998 (rank : 149)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	142	Target Neighborhood Hits	298	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

MMP9_MOUSE
NC score	0.002650 (rank : 150)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	142	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

CHD3_HUMAN
NC score	0.001968 (rank : 151)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	142	Target Neighborhood Hits	397	Shared Neighborhood Hits	11
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

FAN_HUMAN
NC score	0.001760 (rank : 152)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	142	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

ACM5_HUMAN
NC score	0.001444 (rank : 153)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	142	Target Neighborhood Hits	878	Shared Neighborhood Hits	7
SwissProt Accessions	P08912, Q96RG7	Gene names	CHRM5
Domain Architecture
Description	Muscarinic acetylcholine receptor M5.

BARX2_HUMAN
NC score	0.001343 (rank : 154)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	142	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UMQ3, O43518	Gene names	BARX2
Domain Architecture
Description	Homeobox protein BarH-like 2.

ACM1_MOUSE
NC score	0.001311 (rank : 155)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	142	Target Neighborhood Hits	917	Shared Neighborhood Hits	7
SwissProt Accessions	P12657, Q8BJN3	Gene names	Chrm1, Chrm-1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

ACM1_HUMAN
NC score	0.000729 (rank : 156)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	142	Target Neighborhood Hits	908	Shared Neighborhood Hits	7
SwissProt Accessions	P11229	Gene names	CHRM1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

DLG3_HUMAN
NC score	0.000273 (rank : 157)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	142	Target Neighborhood Hits	269	Shared Neighborhood Hits	3
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

E41L2_MOUSE
NC score	-0.000133 (rank : 158)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	142	Target Neighborhood Hits	459	Shared Neighborhood Hits	7
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

HXD9_MOUSE
NC score	-0.001026 (rank : 159)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	142	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	P28357, Q3UYS2	Gene names	Hoxd9, Hox-4.4, Hoxd-9
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4.4) (Hox-5.2).

TEX14_HUMAN
NC score	-0.001037 (rank : 160)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	142	Target Neighborhood Hits	1103	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

BICD2_MOUSE
NC score	-0.001276 (rank : 161)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	142	Target Neighborhood Hits	864	Shared Neighborhood Hits	10
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CELR2_HUMAN
NC score	-0.001780 (rank : 162)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	142	Target Neighborhood Hits	657	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

GASR_HUMAN
NC score	-0.003649 (rank : 163)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	142	Target Neighborhood Hits	874	Shared Neighborhood Hits	5
SwissProt Accessions	P32239	Gene names	CCKBR, CCKRB
Domain Architecture
Description	Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R).

ZNF24_HUMAN
NC score	-0.004533 (rank : 164)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	142	Target Neighborhood Hits	716	Shared Neighborhood Hits	3
SwissProt Accessions	P17028, O14754	Gene names	ZNF24, KOX17, ZNF191, ZSCAN3
Domain Architecture
Description	Zinc finger protein 24 (Zinc finger protein 191) (Zinc finger protein KOX17) (Retinoic acid suppression protein A) (RSG-A) (Zinc finger and SCAN domain-containing protein 3).

ZN263_HUMAN
NC score	-0.004712 (rank : 165)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	142	Target Neighborhood Hits	795	Shared Neighborhood Hits	4
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).