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Network neighborhood for query Sequence : GRHL1_MOUSE

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GRHL1_MOUSE
SwissProt Accessions	Q921D9, Q8K5C1	Gene names	Grhl1, Mgr, Tcfcp2l2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRHL1_HUMAN
θ value	0 (rank : 1)	NC score	0.999222 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZI5, Q53T93, Q6NWN7, Q6NWN8, Q6NWN9, Q8NI33	Gene names	GRHL1, LBP32, MGR, TFCP2L2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32) (NH32) (Mammalian grainyhead).

GRHL1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q921D9, Q8K5C1	Gene names	Grhl1, Mgr, Tcfcp2l2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32).

GRHL2_HUMAN
θ value	0 (rank : 3)	NC score	0.989798 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ISB3, Q6NT03, Q9H8B8	Gene names	GRHL2, BOM, TFCP2L3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL2_MOUSE
θ value	0 (rank : 4)	NC score	0.989518 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL3_MOUSE
θ value	6.19918e-134 (rank : 5)	NC score	0.973861 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWH3	Gene names	Grhl3, Tfcp2l4
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 3 homolog (Transcription factor CP2-like 4).

GRHL3_HUMAN
θ value	1.58377e-121 (rank : 6)	NC score	0.970104 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TE85, Q5TH78, Q86Y06, Q8N407	Gene names	GRHL3, SOM, TFCP2L4
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 3 homolog (Sister of mammalian grainyhead) (Transcription factor CP2-like 4).

TF2L1_MOUSE
θ value	4.01107e-24 (rank : 7)	NC score	0.696627 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UNW5, Q99PF2	Gene names	Tcfcp2l1, Crtr1
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1).

TF2L1_HUMAN
θ value	1.99067e-23 (rank : 8)	NC score	0.688609 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZI6, Q4ZG43	Gene names	TFCP2L1, CRTR1, LBP9
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1) (Transcription factor LBP-9).

UBIP1_MOUSE
θ value	5.79196e-23 (rank : 9)	NC score	0.677209 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q811S7, Q3UPR3, Q3US11, Q60786, Q8C514	Gene names	Ubp1, Cp2b, Nf2d9
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (Nuclear factor 2d9) (NF2d9).

TFCP2_MOUSE
θ value	7.56453e-23 (rank : 10)	NC score	0.678650 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERA0, Q3UGJ4, Q8VC13	Gene names	Tcfcp2
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2.

TFCP2_HUMAN
θ value	1.29031e-22 (rank : 11)	NC score	0.677147 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q12800, Q12801, Q9UD77	Gene names	TFCP2, LSF, SEF
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2 (Transcription factor LSF) (SAA3 enhancer factor).

UBIP1_HUMAN
θ value	1.6852e-22 (rank : 12)	NC score	0.674480 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	83	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZI7, Q68CT0, Q86Y57, Q9H8V0, Q9UD76, Q9UD78	Gene names	UBP1, LBP1
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (LBP-1).

DGKK_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.039111 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	378	Shared Neighborhood Hits	5
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

US6NL_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.015536 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	201	Shared Neighborhood Hits	2
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

CAC1F_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.005494 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	142	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

ODB2_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.017011 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P11182	Gene names	DBT, BCATE2
Domain Architecture
Description	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).

CEP35_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.006923 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	811	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CHSS1_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.006628 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

PLCF_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.020763 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UL3, Q86V89	Gene names	AGPAT6
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase zeta precursor (EC 2.3.1.51) (1-AGP acyltransferase 6) (1-AGPAT 6) (Lysophosphatidic acid acyltransferase-zeta) (LPAAT-zeta).

M3K3_HUMAN
θ value	8.99809 (rank : 20)	NC score	-0.001997 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	885	Shared Neighborhood Hits	2
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

PLCF_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.018485 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2C8, Q3TF78	Gene names	Agpat6
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase zeta precursor (EC 2.3.1.51) (1-AGP acyltransferase 6) (1-AGPAT 6) (Lysophosphatidic acid acyltransferase-zeta) (LPAAT-zeta).

Hits sorted by NC score

GRHL1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q921D9, Q8K5C1	Gene names	Grhl1, Mgr, Tcfcp2l2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32).

GRHL1_HUMAN
NC score	0.999222 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZI5, Q53T93, Q6NWN7, Q6NWN8, Q6NWN9, Q8NI33	Gene names	GRHL1, LBP32, MGR, TFCP2L2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32) (NH32) (Mammalian grainyhead).

GRHL2_HUMAN
NC score	0.989798 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ISB3, Q6NT03, Q9H8B8	Gene names	GRHL2, BOM, TFCP2L3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL2_MOUSE
NC score	0.989518 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL3_MOUSE
NC score	0.973861 (rank : 5)	θ value	6.19918e-134 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWH3	Gene names	Grhl3, Tfcp2l4
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 3 homolog (Transcription factor CP2-like 4).

GRHL3_HUMAN
NC score	0.970104 (rank : 6)	θ value	1.58377e-121 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TE85, Q5TH78, Q86Y06, Q8N407	Gene names	GRHL3, SOM, TFCP2L4
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 3 homolog (Sister of mammalian grainyhead) (Transcription factor CP2-like 4).

TF2L1_MOUSE
NC score	0.696627 (rank : 7)	θ value	4.01107e-24 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UNW5, Q99PF2	Gene names	Tcfcp2l1, Crtr1
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1).

TF2L1_HUMAN
NC score	0.688609 (rank : 8)	θ value	1.99067e-23 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZI6, Q4ZG43	Gene names	TFCP2L1, CRTR1, LBP9
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1) (Transcription factor LBP-9).

TFCP2_MOUSE
NC score	0.678650 (rank : 9)	θ value	7.56453e-23 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERA0, Q3UGJ4, Q8VC13	Gene names	Tcfcp2
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2.

UBIP1_MOUSE
NC score	0.677209 (rank : 10)	θ value	5.79196e-23 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q811S7, Q3UPR3, Q3US11, Q60786, Q8C514	Gene names	Ubp1, Cp2b, Nf2d9
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (Nuclear factor 2d9) (NF2d9).

TFCP2_HUMAN
NC score	0.677147 (rank : 11)	θ value	1.29031e-22 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q12800, Q12801, Q9UD77	Gene names	TFCP2, LSF, SEF
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2 (Transcription factor LSF) (SAA3 enhancer factor).

UBIP1_HUMAN
NC score	0.674480 (rank : 12)	θ value	1.6852e-22 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	83	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZI7, Q68CT0, Q86Y57, Q9H8V0, Q9UD76, Q9UD78	Gene names	UBP1, LBP1
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (LBP-1).

DGKK_HUMAN
NC score	0.039111 (rank : 13)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	378	Shared Neighborhood Hits	5
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

PLCF_HUMAN
NC score	0.020763 (rank : 14)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UL3, Q86V89	Gene names	AGPAT6
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase zeta precursor (EC 2.3.1.51) (1-AGP acyltransferase 6) (1-AGPAT 6) (Lysophosphatidic acid acyltransferase-zeta) (LPAAT-zeta).

PLCF_MOUSE
NC score	0.018485 (rank : 15)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2C8, Q3TF78	Gene names	Agpat6
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase zeta precursor (EC 2.3.1.51) (1-AGP acyltransferase 6) (1-AGPAT 6) (Lysophosphatidic acid acyltransferase-zeta) (LPAAT-zeta).

ODB2_HUMAN
NC score	0.017011 (rank : 16)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P11182	Gene names	DBT, BCATE2
Domain Architecture
Description	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).

US6NL_HUMAN
NC score	0.015536 (rank : 17)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	201	Shared Neighborhood Hits	2
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

CEP35_HUMAN
NC score	0.006923 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	811	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CHSS1_HUMAN
NC score	0.006628 (rank : 19)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CAC1F_MOUSE
NC score	0.005494 (rank : 20)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	142	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

M3K3_HUMAN
NC score	-0.001997 (rank : 21)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	885	Shared Neighborhood Hits	2
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).