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Network neighborhood for query Sequence : GRHL2_MOUSE

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GRHL2_MOUSE
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRHL1_HUMAN
θ value	0 (rank : 1)	NC score	0.989240 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZI5, Q53T93, Q6NWN7, Q6NWN8, Q6NWN9, Q8NI33	Gene names	GRHL1, LBP32, MGR, TFCP2L2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32) (NH32) (Mammalian grainyhead).

GRHL1_MOUSE
θ value	0 (rank : 2)	NC score	0.989518 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q921D9, Q8K5C1	Gene names	Grhl1, Mgr, Tcfcp2l2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32).

GRHL2_HUMAN
θ value	0 (rank : 3)	NC score	0.999186 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ISB3, Q6NT03, Q9H8B8	Gene names	GRHL2, BOM, TFCP2L3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL3_MOUSE
θ value	9.87422e-140 (rank : 5)	NC score	0.973994 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWH3	Gene names	Grhl3, Tfcp2l4
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 3 homolog (Transcription factor CP2-like 4).

GRHL3_HUMAN
θ value	7.33985e-127 (rank : 6)	NC score	0.970178 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TE85, Q5TH78, Q86Y06, Q8N407	Gene names	GRHL3, SOM, TFCP2L4
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 3 homolog (Sister of mammalian grainyhead) (Transcription factor CP2-like 4).

TF2L1_MOUSE
θ value	2.77775e-25 (rank : 7)	NC score	0.681048 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UNW5, Q99PF2	Gene names	Tcfcp2l1, Crtr1
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1).

TF2L1_HUMAN
θ value	3.17815e-21 (rank : 8)	NC score	0.672191 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZI6, Q4ZG43	Gene names	TFCP2L1, CRTR1, LBP9
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1) (Transcription factor LBP-9).

UBIP1_MOUSE
θ value	4.58923e-20 (rank : 9)	NC score	0.659149 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q811S7, Q3UPR3, Q3US11, Q60786, Q8C514	Gene names	Ubp1, Cp2b, Nf2d9
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (Nuclear factor 2d9) (NF2d9).

UBIP1_HUMAN
θ value	7.82807e-20 (rank : 10)	NC score	0.656590 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	83	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZI7, Q68CT0, Q86Y57, Q9H8V0, Q9UD76, Q9UD78	Gene names	UBP1, LBP1
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (LBP-1).

TFCP2_MOUSE
θ value	1.02238e-19 (rank : 11)	NC score	0.660519 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERA0, Q3UGJ4, Q8VC13	Gene names	Tcfcp2
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2.

TFCP2_HUMAN
θ value	1.74391e-19 (rank : 12)	NC score	0.658980 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q12800, Q12801, Q9UD77	Gene names	TFCP2, LSF, SEF
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2 (Transcription factor LSF) (SAA3 enhancer factor).

MX2_MOUSE
θ value	0.365318 (rank : 13)	NC score	0.031019 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

DGKK_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.037099 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	378	Shared Neighborhood Hits	5
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

NEBU_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.019279 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	420	Shared Neighborhood Hits	3
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

BRD3_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.016326 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	402	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

EMAL4_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.022926 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

OTOF_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.013977 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

MX1_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.023884 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

BRD3_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.017518 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

CE290_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.000399 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	1553	Shared Neighborhood Hits	5
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

ZN180_HUMAN
θ value	6.88961 (rank : 22)	NC score	-0.002018 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	752	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJW8, Q9P1U2	Gene names	ZNF180
Domain Architecture
Description	Zinc finger protein 180 (HHZ168).

FANCM_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.005956 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	210	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

SACS_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.010223 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

WNK1_MOUSE
θ value	8.99809 (rank : 25)	NC score	-0.001585 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	1179	Shared Neighborhood Hits	2
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

Hits sorted by NC score

GRHL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL2_HUMAN
NC score	0.999186 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ISB3, Q6NT03, Q9H8B8	Gene names	GRHL2, BOM, TFCP2L3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL1_MOUSE
NC score	0.989518 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q921D9, Q8K5C1	Gene names	Grhl1, Mgr, Tcfcp2l2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32).

GRHL1_HUMAN
NC score	0.989240 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZI5, Q53T93, Q6NWN7, Q6NWN8, Q6NWN9, Q8NI33	Gene names	GRHL1, LBP32, MGR, TFCP2L2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32) (NH32) (Mammalian grainyhead).

GRHL3_MOUSE
NC score	0.973994 (rank : 5)	θ value	9.87422e-140 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWH3	Gene names	Grhl3, Tfcp2l4
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 3 homolog (Transcription factor CP2-like 4).

GRHL3_HUMAN
NC score	0.970178 (rank : 6)	θ value	7.33985e-127 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TE85, Q5TH78, Q86Y06, Q8N407	Gene names	GRHL3, SOM, TFCP2L4
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 3 homolog (Sister of mammalian grainyhead) (Transcription factor CP2-like 4).

TF2L1_MOUSE
NC score	0.681048 (rank : 7)	θ value	2.77775e-25 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UNW5, Q99PF2	Gene names	Tcfcp2l1, Crtr1
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1).

TF2L1_HUMAN
NC score	0.672191 (rank : 8)	θ value	3.17815e-21 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZI6, Q4ZG43	Gene names	TFCP2L1, CRTR1, LBP9
Domain Architecture	No domain graphic available
Description	Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1) (Transcription factor LBP-9).

TFCP2_MOUSE
NC score	0.660519 (rank : 9)	θ value	1.02238e-19 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERA0, Q3UGJ4, Q8VC13	Gene names	Tcfcp2
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2.

UBIP1_MOUSE
NC score	0.659149 (rank : 10)	θ value	4.58923e-20 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q811S7, Q3UPR3, Q3US11, Q60786, Q8C514	Gene names	Ubp1, Cp2b, Nf2d9
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (Nuclear factor 2d9) (NF2d9).

TFCP2_HUMAN
NC score	0.658980 (rank : 11)	θ value	1.74391e-19 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q12800, Q12801, Q9UD77	Gene names	TFCP2, LSF, SEF
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2 (Transcription factor LSF) (SAA3 enhancer factor).

UBIP1_HUMAN
NC score	0.656590 (rank : 12)	θ value	7.82807e-20 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	83	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZI7, Q68CT0, Q86Y57, Q9H8V0, Q9UD76, Q9UD78	Gene names	UBP1, LBP1
Domain Architecture	No domain graphic available
Description	Upstream-binding protein 1 (LBP-1).

DGKK_HUMAN
NC score	0.037099 (rank : 13)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	378	Shared Neighborhood Hits	5
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

MX2_MOUSE
NC score	0.031019 (rank : 14)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX1_HUMAN
NC score	0.023884 (rank : 15)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

EMAL4_HUMAN
NC score	0.022926 (rank : 16)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

NEBU_HUMAN
NC score	0.019279 (rank : 17)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	420	Shared Neighborhood Hits	3
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

BRD3_HUMAN
NC score	0.017518 (rank : 18)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
NC score	0.016326 (rank : 19)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	402	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

OTOF_MOUSE
NC score	0.013977 (rank : 20)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

SACS_HUMAN
NC score	0.010223 (rank : 21)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

FANCM_HUMAN
NC score	0.005956 (rank : 22)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	210	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

CE290_HUMAN
NC score	0.000399 (rank : 23)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	1553	Shared Neighborhood Hits	5
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

WNK1_MOUSE
NC score	-0.001585 (rank : 24)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	1179	Shared Neighborhood Hits	2
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ZN180_HUMAN
NC score	-0.002018 (rank : 25)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	752	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJW8, Q9P1U2	Gene names	ZNF180
Domain Architecture
Description	Zinc finger protein 180 (HHZ168).