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Network neighborhood for query Sequence : MX1_HUMAN

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MX1_HUMAN
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MX1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	62
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

MX1_MOUSE
θ value	0 (rank : 2)	NC score	0.987847 (rank : 3)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

MX2_HUMAN
θ value	0 (rank : 3)	NC score	0.984718 (rank : 4)
Query Neighborhood Hits	62	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

MX2_MOUSE
θ value	0 (rank : 4)	NC score	0.990555 (rank : 2)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

DYN2_MOUSE
θ value	7.47731e-63 (rank : 5)	NC score	0.866133 (rank : 8)
Query Neighborhood Hits	62	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN2_HUMAN
θ value	9.76566e-63 (rank : 6)	NC score	0.866177 (rank : 7)
Query Neighborhood Hits	62	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN1_HUMAN
θ value	2.17557e-62 (rank : 7)	NC score	0.857206 (rank : 11)
Query Neighborhood Hits	62	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_MOUSE
θ value	4.84666e-62 (rank : 8)	NC score	0.862047 (rank : 9)
Query Neighborhood Hits	62	Target Neighborhood Hits	168	Shared Neighborhood Hits	17
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN3_HUMAN
θ value	3.47335e-60 (rank : 9)	NC score	0.859332 (rank : 10)
Query Neighborhood Hits	62	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

DNM1L_HUMAN
θ value	5.55816e-50 (rank : 10)	NC score	0.882693 (rank : 5)
Query Neighborhood Hits	62	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

DNM1L_MOUSE
θ value	4.70527e-49 (rank : 11)	NC score	0.881989 (rank : 6)
Query Neighborhood Hits	62	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

OPA1_MOUSE
θ value	1.42661e-21 (rank : 12)	NC score	0.705752 (rank : 12)
Query Neighborhood Hits	62	Target Neighborhood Hits	79	Shared Neighborhood Hits	17
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_HUMAN
θ value	1.86321e-21 (rank : 13)	NC score	0.703051 (rank : 13)
Query Neighborhood Hits	62	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

MFN1_HUMAN
θ value	0.000602161 (rank : 14)	NC score	0.097781 (rank : 14)
Query Neighborhood Hits	62	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

AKAP9_HUMAN
θ value	0.00175202 (rank : 15)	NC score	0.037032 (rank : 18)
Query Neighborhood Hits	62	Target Neighborhood Hits	1710	Shared Neighborhood Hits	38
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

GAS8_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.039195 (rank : 17)
Query Neighborhood Hits	62	Target Neighborhood Hits	819	Shared Neighborhood Hits	34
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

MYH6_HUMAN
θ value	0.365318 (rank : 17)	NC score	0.018365 (rank : 41)
Query Neighborhood Hits	62	Target Neighborhood Hits	1426	Shared Neighborhood Hits	35
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CCD46_HUMAN
θ value	0.47712 (rank : 18)	NC score	0.027868 (rank : 20)
Query Neighborhood Hits	62	Target Neighborhood Hits	1430	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

ROCK1_HUMAN
θ value	0.62314 (rank : 19)	NC score	0.016914 (rank : 46)
Query Neighborhood Hits	62	Target Neighborhood Hits	2000	Shared Neighborhood Hits	39
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SPTA2_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.017322 (rank : 44)
Query Neighborhood Hits	62	Target Neighborhood Hits	888	Shared Neighborhood Hits	31
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

GFAP_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.012599 (rank : 55)
Query Neighborhood Hits	62	Target Neighborhood Hits	725	Shared Neighborhood Hits	32
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

MPP9_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.043017 (rank : 16)
Query Neighborhood Hits	62	Target Neighborhood Hits	529	Shared Neighborhood Hits	31
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

MYH6_MOUSE
θ value	0.813845 (rank : 23)	NC score	0.018412 (rank : 40)
Query Neighborhood Hits	62	Target Neighborhood Hits	1501	Shared Neighborhood Hits	37
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

LRRC6_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.019633 (rank : 38)
Query Neighborhood Hits	62	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	O88978, Q9CUG2	Gene names	Lrrc6, Lrtp, Mc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

NUCB2_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.023020 (rank : 28)
Query Neighborhood Hits	62	Target Neighborhood Hits	321	Shared Neighborhood Hits	20
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

RCN2_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.032867 (rank : 19)
Query Neighborhood Hits	62	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q14257	Gene names	RCN2, ERC55
Domain Architecture
Description	Reticulocalbin-2 precursor (Calcium-binding protein ERC-55) (E6- binding protein) (E6BP).

SYNE1_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.020797 (rank : 34)
Query Neighborhood Hits	62	Target Neighborhood Hits	1484	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

UCHL5_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.021987 (rank : 29)
Query Neighborhood Hits	62	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUP7, Q9CVJ4, Q9CXZ3, Q9R107	Gene names	Uchl5, Uch37
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase isozyme L5 (EC 3.4.19.12) (UCH- L5) (Ubiquitin thioesterase L5) (Ubiquitin C-terminal hydrolase UCH37).

GOGB1_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.021283 (rank : 33)
Query Neighborhood Hits	62	Target Neighborhood Hits	2297	Shared Neighborhood Hits	38
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MY18A_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.018101 (rank : 42)
Query Neighborhood Hits	62	Target Neighborhood Hits	1989	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

WWC1_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.023953 (rank : 23)
Query Neighborhood Hits	62	Target Neighborhood Hits	290	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.023280 (rank : 26)
Query Neighborhood Hits	62	Target Neighborhood Hits	290	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

I13R1_MOUSE
θ value	2.36792 (rank : 33)	NC score	0.015167 (rank : 51)
Query Neighborhood Hits	62	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

KIF5C_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.014048 (rank : 52)
Query Neighborhood Hits	62	Target Neighborhood Hits	974	Shared Neighborhood Hits	31
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

ROCK1_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.016257 (rank : 48)
Query Neighborhood Hits	62	Target Neighborhood Hits	2126	Shared Neighborhood Hits	41
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

CE290_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.023580 (rank : 25)
Query Neighborhood Hits	62	Target Neighborhood Hits	1553	Shared Neighborhood Hits	37
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CEND1_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.006613 (rank : 58)
Query Neighborhood Hits	62	Target Neighborhood Hits	284	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

GOGA1_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.021766 (rank : 32)
Query Neighborhood Hits	62	Target Neighborhood Hits	1222	Shared Neighborhood Hits	34
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GRHL2_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.021814 (rank : 31)
Query Neighborhood Hits	62	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ISB3, Q6NT03, Q9H8B8	Gene names	GRHL2, BOM, TFCP2L3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL2_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.023884 (rank : 24)
Query Neighborhood Hits	62	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

EVPL_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.017861 (rank : 43)
Query Neighborhood Hits	62	Target Neighborhood Hits	895	Shared Neighborhood Hits	28
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

GPR98_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.008068 (rank : 57)
Query Neighborhood Hits	62	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

KMHN1_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.020347 (rank : 35)
Query Neighborhood Hits	62	Target Neighborhood Hits	949	Shared Neighborhood Hits	32
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

MY18A_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.019824 (rank : 36)
Query Neighborhood Hits	62	Target Neighborhood Hits	1929	Shared Neighborhood Hits	37
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

YSK4_HUMAN
θ value	4.03905 (rank : 45)	NC score	-0.000672 (rank : 63)
Query Neighborhood Hits	62	Target Neighborhood Hits	921	Shared Neighborhood Hits	4
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

ABCA9_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.004983 (rank : 61)
Query Neighborhood Hits	62	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

IQGA1_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.016717 (rank : 47)
Query Neighborhood Hits	62	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

IQGA1_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.015677 (rank : 50)
Query Neighborhood Hits	62	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

OFD1_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.024131 (rank : 22)
Query Neighborhood Hits	62	Target Neighborhood Hits	753	Shared Neighborhood Hits	30
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

RAI14_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.013838 (rank : 53)
Query Neighborhood Hits	62	Target Neighborhood Hits	1505	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

APOB_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.019721 (rank : 37)
Query Neighborhood Hits	62	Target Neighborhood Hits	202	Shared Neighborhood Hits	15
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

CKAP4_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.023127 (rank : 27)
Query Neighborhood Hits	62	Target Neighborhood Hits	592	Shared Neighborhood Hits	28
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

RPGR1_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.021820 (rank : 30)
Query Neighborhood Hits	62	Target Neighborhood Hits	578	Shared Neighborhood Hits	29
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

ABC8A_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.004311 (rank : 62)
Query Neighborhood Hits	62	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

CK5P2_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.018744 (rank : 39)
Query Neighborhood Hits	62	Target Neighborhood Hits	1433	Shared Neighborhood Hits	36
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CTGE5_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.017245 (rank : 45)
Query Neighborhood Hits	62	Target Neighborhood Hits	928	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

HS90B_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.005529 (rank : 60)
Query Neighborhood Hits	62	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

ITSN2_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.011989 (rank : 56)
Query Neighborhood Hits	62	Target Neighborhood Hits	1173	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

KIF5A_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.012741 (rank : 54)
Query Neighborhood Hits	62	Target Neighborhood Hits	843	Shared Neighborhood Hits	31
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KRHB6_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.006268 (rank : 59)
Query Neighborhood Hits	62	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

RBCC1_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.026391 (rank : 21)
Query Neighborhood Hits	62	Target Neighborhood Hits	1023	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

UCHL5_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.015979 (rank : 49)
Query Neighborhood Hits	62	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5K5, Q5LJA6, Q5LJA7, Q8TBS4, Q96BJ9, Q9H1W5, Q9P0I3, Q9UQN2	Gene names	UCHL5, UCH37
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase isozyme L5 (EC 3.4.19.12) (UCH- L5) (Ubiquitin thioesterase L5) (Ubiquitin C-terminal hydrolase UCH37).

CNKR1_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.050645 (rank : 15)
Query Neighborhood Hits	62	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

Hits sorted by NC score

MX1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	62
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

MX2_MOUSE
NC score	0.990555 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX1_MOUSE
NC score	0.987847 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	62	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

MX2_HUMAN
NC score	0.984718 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	62	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

DNM1L_HUMAN
NC score	0.882693 (rank : 5)	θ value	5.55816e-50 (rank : 10)
Query Neighborhood Hits	62	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

DNM1L_MOUSE
NC score	0.881989 (rank : 6)	θ value	4.70527e-49 (rank : 11)
Query Neighborhood Hits	62	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

DYN2_HUMAN
NC score	0.866177 (rank : 7)	θ value	9.76566e-63 (rank : 6)
Query Neighborhood Hits	62	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN2_MOUSE
NC score	0.866133 (rank : 8)	θ value	7.47731e-63 (rank : 5)
Query Neighborhood Hits	62	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN1_MOUSE
NC score	0.862047 (rank : 9)	θ value	4.84666e-62 (rank : 8)
Query Neighborhood Hits	62	Target Neighborhood Hits	168	Shared Neighborhood Hits	17
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN3_HUMAN
NC score	0.859332 (rank : 10)	θ value	3.47335e-60 (rank : 9)
Query Neighborhood Hits	62	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

DYN1_HUMAN
NC score	0.857206 (rank : 11)	θ value	2.17557e-62 (rank : 7)
Query Neighborhood Hits	62	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

OPA1_MOUSE
NC score	0.705752 (rank : 12)	θ value	1.42661e-21 (rank : 12)
Query Neighborhood Hits	62	Target Neighborhood Hits	79	Shared Neighborhood Hits	17
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_HUMAN
NC score	0.703051 (rank : 13)	θ value	1.86321e-21 (rank : 13)
Query Neighborhood Hits	62	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

MFN1_HUMAN
NC score	0.097781 (rank : 14)	θ value	0.000602161 (rank : 14)
Query Neighborhood Hits	62	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

CNKR1_HUMAN
NC score	0.050645 (rank : 15)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	62	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

MPP9_HUMAN
NC score	0.043017 (rank : 16)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	62	Target Neighborhood Hits	529	Shared Neighborhood Hits	31
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

GAS8_HUMAN
NC score	0.039195 (rank : 17)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	62	Target Neighborhood Hits	819	Shared Neighborhood Hits	34
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

AKAP9_HUMAN
NC score	0.037032 (rank : 18)	θ value	0.00175202 (rank : 15)
Query Neighborhood Hits	62	Target Neighborhood Hits	1710	Shared Neighborhood Hits	38
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

RCN2_HUMAN
NC score	0.032867 (rank : 19)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	62	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q14257	Gene names	RCN2, ERC55
Domain Architecture
Description	Reticulocalbin-2 precursor (Calcium-binding protein ERC-55) (E6- binding protein) (E6BP).

CCD46_HUMAN
NC score	0.027868 (rank : 20)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	62	Target Neighborhood Hits	1430	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

RBCC1_HUMAN
NC score	0.026391 (rank : 21)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	62	Target Neighborhood Hits	1023	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

OFD1_HUMAN
NC score	0.024131 (rank : 22)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	62	Target Neighborhood Hits	753	Shared Neighborhood Hits	30
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

WWC1_HUMAN
NC score	0.023953 (rank : 23)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	62	Target Neighborhood Hits	290	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

GRHL2_MOUSE
NC score	0.023884 (rank : 24)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	62	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

CE290_HUMAN
NC score	0.023580 (rank : 25)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	62	Target Neighborhood Hits	1553	Shared Neighborhood Hits	37
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

WWC1_MOUSE
NC score	0.023280 (rank : 26)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	62	Target Neighborhood Hits	290	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

CKAP4_HUMAN
NC score	0.023127 (rank : 27)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	62	Target Neighborhood Hits	592	Shared Neighborhood Hits	28
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

NUCB2_HUMAN
NC score	0.023020 (rank : 28)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	62	Target Neighborhood Hits	321	Shared Neighborhood Hits	20
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

UCHL5_MOUSE
NC score	0.021987 (rank : 29)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	62	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUP7, Q9CVJ4, Q9CXZ3, Q9R107	Gene names	Uchl5, Uch37
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase isozyme L5 (EC 3.4.19.12) (UCH- L5) (Ubiquitin thioesterase L5) (Ubiquitin C-terminal hydrolase UCH37).

RPGR1_HUMAN
NC score	0.021820 (rank : 30)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	62	Target Neighborhood Hits	578	Shared Neighborhood Hits	29
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

GRHL2_HUMAN
NC score	0.021814 (rank : 31)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	62	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ISB3, Q6NT03, Q9H8B8	Gene names	GRHL2, BOM, TFCP2L3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GOGA1_HUMAN
NC score	0.021766 (rank : 32)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	62	Target Neighborhood Hits	1222	Shared Neighborhood Hits	34
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGB1_HUMAN
NC score	0.021283 (rank : 33)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	62	Target Neighborhood Hits	2297	Shared Neighborhood Hits	38
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SYNE1_HUMAN
NC score	0.020797 (rank : 34)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	62	Target Neighborhood Hits	1484	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

KMHN1_MOUSE
NC score	0.020347 (rank : 35)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	62	Target Neighborhood Hits	949	Shared Neighborhood Hits	32
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

MY18A_HUMAN
NC score	0.019824 (rank : 36)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	62	Target Neighborhood Hits	1929	Shared Neighborhood Hits	37
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

APOB_HUMAN
NC score	0.019721 (rank : 37)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	62	Target Neighborhood Hits	202	Shared Neighborhood Hits	15
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

LRRC6_MOUSE
NC score	0.019633 (rank : 38)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	62	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	O88978, Q9CUG2	Gene names	Lrrc6, Lrtp, Mc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

CK5P2_HUMAN
NC score	0.018744 (rank : 39)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	62	Target Neighborhood Hits	1433	Shared Neighborhood Hits	36
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

MYH6_MOUSE
NC score	0.018412 (rank : 40)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	62	Target Neighborhood Hits	1501	Shared Neighborhood Hits	37
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_HUMAN
NC score	0.018365 (rank : 41)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	62	Target Neighborhood Hits	1426	Shared Neighborhood Hits	35
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MY18A_MOUSE
NC score	0.018101 (rank : 42)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	62	Target Neighborhood Hits	1989	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

EVPL_HUMAN
NC score	0.017861 (rank : 43)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	62	Target Neighborhood Hits	895	Shared Neighborhood Hits	28
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

SPTA2_HUMAN
NC score	0.017322 (rank : 44)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	62	Target Neighborhood Hits	888	Shared Neighborhood Hits	31
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

CTGE5_MOUSE
NC score	0.017245 (rank : 45)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	62	Target Neighborhood Hits	928	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

ROCK1_HUMAN
NC score	0.016914 (rank : 46)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	62	Target Neighborhood Hits	2000	Shared Neighborhood Hits	39
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

IQGA1_HUMAN
NC score	0.016717 (rank : 47)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	62	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

ROCK1_MOUSE
NC score	0.016257 (rank : 48)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	62	Target Neighborhood Hits	2126	Shared Neighborhood Hits	41
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

UCHL5_HUMAN
NC score	0.015979 (rank : 49)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	62	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5K5, Q5LJA6, Q5LJA7, Q8TBS4, Q96BJ9, Q9H1W5, Q9P0I3, Q9UQN2	Gene names	UCHL5, UCH37
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase isozyme L5 (EC 3.4.19.12) (UCH- L5) (Ubiquitin thioesterase L5) (Ubiquitin C-terminal hydrolase UCH37).

IQGA1_MOUSE
NC score	0.015677 (rank : 50)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	62	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

I13R1_MOUSE
NC score	0.015167 (rank : 51)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	62	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

KIF5C_HUMAN
NC score	0.014048 (rank : 52)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	62	Target Neighborhood Hits	974	Shared Neighborhood Hits	31
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

RAI14_MOUSE
NC score	0.013838 (rank : 53)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	62	Target Neighborhood Hits	1505	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

KIF5A_HUMAN
NC score	0.012741 (rank : 54)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	62	Target Neighborhood Hits	843	Shared Neighborhood Hits	31
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

GFAP_MOUSE
NC score	0.012599 (rank : 55)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	62	Target Neighborhood Hits	725	Shared Neighborhood Hits	32
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

ITSN2_HUMAN
NC score	0.011989 (rank : 56)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	62	Target Neighborhood Hits	1173	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

GPR98_MOUSE
NC score	0.008068 (rank : 57)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	62	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

CEND1_HUMAN
NC score	0.006613 (rank : 58)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	62	Target Neighborhood Hits	284	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

KRHB6_MOUSE
NC score	0.006268 (rank : 59)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	62	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

HS90B_MOUSE
NC score	0.005529 (rank : 60)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	62	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

ABCA9_HUMAN
NC score	0.004983 (rank : 61)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	62	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABC8A_MOUSE
NC score	0.004311 (rank : 62)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	62	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

YSK4_HUMAN
NC score	-0.000672 (rank : 63)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	62	Target Neighborhood Hits	921	Shared Neighborhood Hits	4
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).