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Network neighborhood for query Sequence : HS90B_MOUSE

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HS90B_MOUSE
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HS90A_HUMAN
θ value	0 (rank : 1)	NC score	0.977869 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	144	Shared Neighborhood Hits	50
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90A_MOUSE
θ value	0 (rank : 2)	NC score	0.979765 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

HS90B_HUMAN
θ value	0 (rank : 3)	NC score	0.998135 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90B_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

ENPL_HUMAN
θ value	1.0648e-109 (rank : 5)	NC score	0.933307 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

ENPL_MOUSE
θ value	6.90186e-109 (rank : 6)	NC score	0.931581 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

TRAP1_HUMAN
θ value	3.60269e-49 (rank : 7)	NC score	0.855428 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

TRAP1_MOUSE
θ value	1.36902e-48 (rank : 8)	NC score	0.854343 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

SEC63_HUMAN
θ value	0.0148317 (rank : 9)	NC score	0.107818 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	586	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
θ value	0.0330416 (rank : 10)	NC score	0.101448 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	601	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

TRIPB_HUMAN
θ value	0.0431538 (rank : 11)	NC score	0.038145 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	1587	Shared Neighborhood Hits	44
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

KI67_HUMAN
θ value	0.0563607 (rank : 12)	NC score	0.058169 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	581	Shared Neighborhood Hits	18
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

CND3_HUMAN
θ value	0.0961366 (rank : 13)	NC score	0.080262 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BPX3, Q96SV9, Q9BUR3, Q9BVY1, Q9H914, Q9H9Z6, Q9HBI9	Gene names	NCAPG, CAPG, NYMEL3
Domain Architecture
Description	Condensin complex subunit 3 (Non-SMC condensin I complex subunit G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (XCAP-G homolog) (Antigen NY-MEL-3).

RELN_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.046467 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

NUF2_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.037940 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	661	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

HSF2B_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.144171 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

OXSR1_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.012642 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	865	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

PRI1_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.089966 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

SYNE1_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.028831 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	1484	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

LAMA2_MOUSE
θ value	0.47712 (rank : 20)	NC score	0.016738 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	1198	Shared Neighborhood Hits	29
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SMC2_HUMAN
θ value	0.62314 (rank : 21)	NC score	0.037353 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	1405	Shared Neighborhood Hits	47
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

AT10A_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.021567 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	O60312, Q969I4	Gene names	ATP10A, ATP10C, ATPVC, KIAA0566
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPVA) (Aminophospholipid translocase VA).

KIF5A_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.019853 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	859	Shared Neighborhood Hits	32
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

OXSR1_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.011295 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

PHF3_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.040352 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	23
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

CCD46_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.023852 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	1405	Shared Neighborhood Hits	40
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

I5P2_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.014264 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

TXND2_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.033895 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	828	Shared Neighborhood Hits	40
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

DCDC2_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.023484 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

DYH11_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.025208 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	234	Shared Neighborhood Hits	20
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

RELN_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.035908 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

CEP55_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.027082 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

E2F6_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.017440 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

NAF1_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.025371 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	937	Shared Neighborhood Hits	34
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

CLC6A_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.012691 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EIG7	Gene names	CLEC6A, CLECSF10, DECTIN2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

EVI1_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.001986 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	924	Shared Neighborhood Hits	16
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

MPIP3_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.031126 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

MPP8_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.025803 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	948	Shared Neighborhood Hits	37
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NOC2L_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.026067 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3T9, Q5SVA3, Q9BTN6	Gene names	NOC2L
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

P52K_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.024497 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

SMC1A_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.030608 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	1346	Shared Neighborhood Hits	44
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.029602 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	1384	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC2_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.037901 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	1131	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

ST1E1_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.023162 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P49888, Q8N6X5	Gene names	SULT1E1, STE
Domain Architecture
Description	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen- preferring) (EST-1).

ZA2G_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.007748 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q64726	Gene names	Azgp1
Domain Architecture
Description	Zinc-alpha-2-glycoprotein precursor (Zn-alpha-2-glycoprotein) (Zn- alpha-2-GP).

ZN318_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.039485 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	642	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ANR11_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.019115 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	1289	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

BAZ1A_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.021429 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BPAEA_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.021492 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	1369	Shared Neighborhood Hits	36
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD46_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.022404 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	1430	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CJ092_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.031197 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYW2, Q5JSF7, Q9NTQ5	Gene names	C10orf92
Domain Architecture	No domain graphic available
Description	Protein C10orf92.

RGS6_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.011854 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

STK39_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.007281 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	882	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

STK39_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.007902 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	915	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

TCAL5_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.031000 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	806	Shared Neighborhood Hits	23
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ADA30_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.014636 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	391	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

BPA1_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.017632 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	1477	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

E2F6_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.021672 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

IF4G3_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.017248 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.017163 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

KIF5C_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.016105 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	974	Shared Neighborhood Hits	32
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MRIP_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.025966 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	578	Shared Neighborhood Hits	25
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.026268 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	569	Shared Neighborhood Hits	27
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

NSBP1_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.034181 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	681	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PMS2_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.024877 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

RAD50_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.027003 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	1317	Shared Neighborhood Hits	41
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

REST_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.016852 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	1506	Shared Neighborhood Hits	38
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TARA_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.024778 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	1133	Shared Neighborhood Hits	27
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

AT10A_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.012125 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	O54827, Q8R3B8	Gene names	Atp10a, Atpc5, Pfatp
Domain Architecture
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (P-locus fat-associated ATPase).

DYH9_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.023947 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

LEO1_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.040673 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	958	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.043806 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LMO7_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.019363 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	507	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

NCOAT_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.010321 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	O60502, O75166, Q86WV0, Q8IV98, Q9BVA5, Q9HAR0	Gene names	MGEA5, HEXC, KIAA0679, MEA5
Domain Architecture	No domain graphic available
Description	Bifunctional protein NCOAT (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (Meningioma-expressed antigen 5) [Includes: Beta- hexosaminidase (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase) (Beta-N- acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D- glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (EC 2.3.1.48) (HAT)].

NOL10_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.019944 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	254	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

SALL1_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.000641 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	826	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

SYCP1_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.029313 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	1456	Shared Neighborhood Hits	45
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TEX14_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.007666 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	1333	Shared Neighborhood Hits	31
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TGON1_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.018318 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

ANLN_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.026535 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CDKL2_MOUSE
θ value	8.99809 (rank : 81)	NC score	-0.000134 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	854	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QUK0, Q3UL60, Q3V3X7, Q9QYI1, Q9QYI2	Gene names	Cdkl2, Kkiamre, Kkm
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE).

CP135_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.017911 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	1290	Shared Neighborhood Hits	39
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DESP_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.018298 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DNJC8_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.015714 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

E41L2_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.006628 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	459	Shared Neighborhood Hits	21
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

IWS1_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.014273 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	1241	Shared Neighborhood Hits	29
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.014830 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	1258	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KIF5A_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.014205 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	843	Shared Neighborhood Hits	29
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

MX1_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.005529 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

PEG3_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.007189 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	1101	Shared Neighborhood Hits	20
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PLXD1_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.003262 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

REST_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.017733 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	1605	Shared Neighborhood Hits	45
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RXINP_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.019063 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

SGOL1_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.012846 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

SHOX_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.004828 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	363	Shared Neighborhood Hits	4
SwissProt Accessions	O15266, O00412, O00413, O15267	Gene names	SHOX, PHOG
Domain Architecture
Description	Short stature homeobox protein (Short stature homeobox-containing protein) (Pseudoautosomal homeobox-containing osteogenic protein).

SMRC2_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.020982 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	487	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TSH1_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.027689 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	675	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

ZBT24_HUMAN
θ value	8.99809 (rank : 98)	NC score	-0.000813 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	870	Shared Neighborhood Hits	9
SwissProt Accessions	O43167, Q5TED5, Q8N455	Gene names	ZBTB24, KIAA0441, ZNF450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450).

Hits sorted by NC score

HS90B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

HS90B_HUMAN
NC score	0.998135 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90A_MOUSE
NC score	0.979765 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

HS90A_HUMAN
NC score	0.977869 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	144	Shared Neighborhood Hits	50
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

ENPL_HUMAN
NC score	0.933307 (rank : 5)	θ value	1.0648e-109 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

ENPL_MOUSE
NC score	0.931581 (rank : 6)	θ value	6.90186e-109 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

TRAP1_HUMAN
NC score	0.855428 (rank : 7)	θ value	3.60269e-49 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

TRAP1_MOUSE
NC score	0.854343 (rank : 8)	θ value	1.36902e-48 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

HSF2B_HUMAN
NC score	0.144171 (rank : 9)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

SEC63_HUMAN
NC score	0.107818 (rank : 10)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	586	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
NC score	0.101448 (rank : 11)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	601	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

PRI1_MOUSE
NC score	0.089966 (rank : 12)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

CND3_HUMAN
NC score	0.080262 (rank : 13)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BPX3, Q96SV9, Q9BUR3, Q9BVY1, Q9H914, Q9H9Z6, Q9HBI9	Gene names	NCAPG, CAPG, NYMEL3
Domain Architecture
Description	Condensin complex subunit 3 (Non-SMC condensin I complex subunit G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (XCAP-G homolog) (Antigen NY-MEL-3).

KI67_HUMAN
NC score	0.058169 (rank : 14)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	581	Shared Neighborhood Hits	18
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

RELN_HUMAN
NC score	0.046467 (rank : 15)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

LEO1_MOUSE
NC score	0.043806 (rank : 16)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.040673 (rank : 17)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	958	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PHF3_HUMAN
NC score	0.040352 (rank : 18)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	23
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

ZN318_MOUSE
NC score	0.039485 (rank : 19)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	642	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

TRIPB_HUMAN
NC score	0.038145 (rank : 20)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	1587	Shared Neighborhood Hits	44
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

NUF2_HUMAN
NC score	0.037940 (rank : 21)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	661	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

SMC2_MOUSE
NC score	0.037901 (rank : 22)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	1131	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SMC2_HUMAN
NC score	0.037353 (rank : 23)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	1405	Shared Neighborhood Hits	47
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

RELN_MOUSE
NC score	0.035908 (rank : 24)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

NSBP1_MOUSE
NC score	0.034181 (rank : 25)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	681	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

TXND2_MOUSE
NC score	0.033895 (rank : 26)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	828	Shared Neighborhood Hits	40
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CJ092_HUMAN
NC score	0.031197 (rank : 27)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYW2, Q5JSF7, Q9NTQ5	Gene names	C10orf92
Domain Architecture	No domain graphic available
Description	Protein C10orf92.

MPIP3_HUMAN
NC score	0.031126 (rank : 28)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

TCAL5_HUMAN
NC score	0.031000 (rank : 29)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	806	Shared Neighborhood Hits	23
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

SMC1A_HUMAN
NC score	0.030608 (rank : 30)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	1346	Shared Neighborhood Hits	44
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
NC score	0.029602 (rank : 31)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	1384	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SYCP1_MOUSE
NC score	0.029313 (rank : 32)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	1456	Shared Neighborhood Hits	45
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYNE1_HUMAN
NC score	0.028831 (rank : 33)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	1484	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TSH1_MOUSE
NC score	0.027689 (rank : 34)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	675	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

CEP55_MOUSE
NC score	0.027082 (rank : 35)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

RAD50_HUMAN
NC score	0.027003 (rank : 36)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	1317	Shared Neighborhood Hits	41
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

ANLN_HUMAN
NC score	0.026535 (rank : 37)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

MRIP_MOUSE
NC score	0.026268 (rank : 38)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	569	Shared Neighborhood Hits	27
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

NOC2L_HUMAN
NC score	0.026067 (rank : 39)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3T9, Q5SVA3, Q9BTN6	Gene names	NOC2L
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

MRIP_HUMAN
NC score	0.025966 (rank : 40)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	578	Shared Neighborhood Hits	25
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MPP8_HUMAN
NC score	0.025803 (rank : 41)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	948	Shared Neighborhood Hits	37
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NAF1_HUMAN
NC score	0.025371 (rank : 42)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	937	Shared Neighborhood Hits	34
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

DYH11_HUMAN
NC score	0.025208 (rank : 43)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	234	Shared Neighborhood Hits	20
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

PMS2_HUMAN
NC score	0.024877 (rank : 44)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

TARA_MOUSE
NC score	0.024778 (rank : 45)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	1133	Shared Neighborhood Hits	27
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

P52K_HUMAN
NC score	0.024497 (rank : 46)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

DYH9_HUMAN
NC score	0.023947 (rank : 47)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

CCD46_MOUSE
NC score	0.023852 (rank : 48)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	1405	Shared Neighborhood Hits	40
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

DCDC2_HUMAN
NC score	0.023484 (rank : 49)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

ST1E1_HUMAN
NC score	0.023162 (rank : 50)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P49888, Q8N6X5	Gene names	SULT1E1, STE
Domain Architecture
Description	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen- preferring) (EST-1).

CCD46_HUMAN
NC score	0.022404 (rank : 51)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	1430	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

E2F6_MOUSE
NC score	0.021672 (rank : 52)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

AT10A_HUMAN
NC score	0.021567 (rank : 53)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	O60312, Q969I4	Gene names	ATP10A, ATP10C, ATPVC, KIAA0566
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPVA) (Aminophospholipid translocase VA).

BPAEA_HUMAN
NC score	0.021492 (rank : 54)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	1369	Shared Neighborhood Hits	36
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BAZ1A_HUMAN
NC score	0.021429 (rank : 55)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

SMRC2_MOUSE
NC score	0.020982 (rank : 56)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	487	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

NOL10_HUMAN
NC score	0.019944 (rank : 57)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	254	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

KIF5A_MOUSE
NC score	0.019853 (rank : 58)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	859	Shared Neighborhood Hits	32
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

LMO7_HUMAN
NC score	0.019363 (rank : 59)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	507	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

ANR11_HUMAN
NC score	0.019115 (rank : 60)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	1289	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

RXINP_HUMAN
NC score	0.019063 (rank : 61)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

TGON1_MOUSE
NC score	0.018318 (rank : 62)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

DESP_HUMAN
NC score	0.018298 (rank : 63)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

CP135_HUMAN
NC score	0.017911 (rank : 64)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	1290	Shared Neighborhood Hits	39
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

REST_HUMAN
NC score	0.017733 (rank : 65)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	1605	Shared Neighborhood Hits	45
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

BPA1_MOUSE
NC score	0.017632 (rank : 66)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	1477	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

E2F6_HUMAN
NC score	0.017440 (rank : 67)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

IF4G3_HUMAN
NC score	0.017248 (rank : 68)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
NC score	0.017163 (rank : 69)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

REST_MOUSE
NC score	0.016852 (rank : 70)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	1506	Shared Neighborhood Hits	38
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

LAMA2_MOUSE
NC score	0.016738 (rank : 71)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	1198	Shared Neighborhood Hits	29
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KIF5C_HUMAN
NC score	0.016105 (rank : 72)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	974	Shared Neighborhood Hits	32
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

DNJC8_MOUSE
NC score	0.015714 (rank : 73)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

IWS1_MOUSE
NC score	0.014830 (rank : 74)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	1258	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ADA30_HUMAN
NC score	0.014636 (rank : 75)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	391	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

IWS1_HUMAN
NC score	0.014273 (rank : 76)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	1241	Shared Neighborhood Hits	29
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

I5P2_HUMAN
NC score	0.014264 (rank : 77)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

KIF5A_HUMAN
NC score	0.014205 (rank : 78)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	843	Shared Neighborhood Hits	29
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

SGOL1_HUMAN
NC score	0.012846 (rank : 79)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

CLC6A_HUMAN
NC score	0.012691 (rank : 80)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EIG7	Gene names	CLEC6A, CLECSF10, DECTIN2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

OXSR1_MOUSE
NC score	0.012642 (rank : 81)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	865	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

AT10A_MOUSE
NC score	0.012125 (rank : 82)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	O54827, Q8R3B8	Gene names	Atp10a, Atpc5, Pfatp
Domain Architecture
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (P-locus fat-associated ATPase).

RGS6_HUMAN
NC score	0.011854 (rank : 83)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

OXSR1_HUMAN
NC score	0.011295 (rank : 84)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

NCOAT_HUMAN
NC score	0.010321 (rank : 85)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	O60502, O75166, Q86WV0, Q8IV98, Q9BVA5, Q9HAR0	Gene names	MGEA5, HEXC, KIAA0679, MEA5
Domain Architecture	No domain graphic available
Description	Bifunctional protein NCOAT (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (Meningioma-expressed antigen 5) [Includes: Beta- hexosaminidase (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase) (Beta-N- acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D- glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (EC 2.3.1.48) (HAT)].

STK39_MOUSE
NC score	0.007902 (rank : 86)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	915	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

ZA2G_MOUSE
NC score	0.007748 (rank : 87)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q64726	Gene names	Azgp1
Domain Architecture
Description	Zinc-alpha-2-glycoprotein precursor (Zn-alpha-2-glycoprotein) (Zn- alpha-2-GP).

TEX14_MOUSE
NC score	0.007666 (rank : 88)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	1333	Shared Neighborhood Hits	31
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

STK39_HUMAN
NC score	0.007281 (rank : 89)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	882	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

PEG3_MOUSE
NC score	0.007189 (rank : 90)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	1101	Shared Neighborhood Hits	20
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

E41L2_MOUSE
NC score	0.006628 (rank : 91)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	459	Shared Neighborhood Hits	21
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MX1_HUMAN
NC score	0.005529 (rank : 92)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

SHOX_HUMAN
NC score	0.004828 (rank : 93)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	363	Shared Neighborhood Hits	4
SwissProt Accessions	O15266, O00412, O00413, O15267	Gene names	SHOX, PHOG
Domain Architecture
Description	Short stature homeobox protein (Short stature homeobox-containing protein) (Pseudoautosomal homeobox-containing osteogenic protein).

PLXD1_HUMAN
NC score	0.003262 (rank : 94)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

EVI1_HUMAN
NC score	0.001986 (rank : 95)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	924	Shared Neighborhood Hits	16
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

SALL1_MOUSE
NC score	0.000641 (rank : 96)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	826	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

CDKL2_MOUSE
NC score	-0.000134 (rank : 97)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	854	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QUK0, Q3UL60, Q3V3X7, Q9QYI1, Q9QYI2	Gene names	Cdkl2, Kkiamre, Kkm
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE).

ZBT24_HUMAN
NC score	-0.000813 (rank : 98)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	870	Shared Neighborhood Hits	9
SwissProt Accessions	O43167, Q5TED5, Q8N455	Gene names	ZBTB24, KIAA0441, ZNF450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450).