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Network neighborhood for query Sequence : PMS2_HUMAN

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PMS2_HUMAN
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PMS2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PMS2_MOUSE
θ value	0 (rank : 2)	NC score	0.959278 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PMS1_HUMAN
θ value	6.58091e-43 (rank : 3)	NC score	0.700437 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

MLH1_HUMAN
θ value	3.61106e-41 (rank : 4)	NC score	0.743396 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

MLH1_MOUSE
θ value	6.15952e-41 (rank : 5)	NC score	0.740578 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JK91, Q62454	Gene names	Mlh1
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

MLH3_HUMAN
θ value	6.85773e-16 (rank : 6)	NC score	0.568280 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

LPIN2_MOUSE
θ value	0.00390308 (rank : 7)	NC score	0.073685 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PI5, Q8C357, Q8C7I8, Q8CC85, Q8CHR7	Gene names	Lpin2
Domain Architecture
Description	Lipin-2.

CJ078_MOUSE
θ value	0.00869519 (rank : 8)	NC score	0.078164 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	559	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CHD9_HUMAN
θ value	0.0113563 (rank : 9)	NC score	0.059218 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	0.0113563 (rank : 10)	NC score	0.050872 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

LPIN2_HUMAN
θ value	0.0193708 (rank : 11)	NC score	0.077323 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

UBP34_MOUSE
θ value	0.0193708 (rank : 12)	NC score	0.066808 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

CD19_HUMAN
θ value	0.0252991 (rank : 13)	NC score	0.074530 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	P15391, Q96S68, Q9BRD6	Gene names	CD19
Domain Architecture
Description	B-lymphocyte antigen CD19 precursor (Differentiation antigen CD19) (B- lymphocyte surface antigen B4) (Leu-12).

UBP34_HUMAN
θ value	0.0252991 (rank : 14)	NC score	0.065695 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	210	Shared Neighborhood Hits	18
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

DSPP_MOUSE
θ value	0.0330416 (rank : 15)	NC score	0.081882 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TXLNG_HUMAN
θ value	0.0563607 (rank : 16)	NC score	0.028439 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	568	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

ZCH14_MOUSE
θ value	0.125558 (rank : 17)	NC score	0.060589 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

FILA_HUMAN
θ value	0.163984 (rank : 18)	NC score	0.065364 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	685	Shared Neighborhood Hits	44
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

WASF3_MOUSE
θ value	0.163984 (rank : 19)	NC score	0.043538 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ZCPW1_MOUSE
θ value	0.163984 (rank : 20)	NC score	0.055883 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

AFF4_MOUSE
θ value	0.21417 (rank : 21)	NC score	0.059350 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	581	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

IP3KC_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.049297 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

ZN592_MOUSE
θ value	0.21417 (rank : 23)	NC score	0.013724 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	768	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

ENL_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.057230 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	305	Shared Neighborhood Hits	19
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

MAGC1_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.024416 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	431	Shared Neighborhood Hits	14
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MUC13_MOUSE
θ value	0.279714 (rank : 26)	NC score	0.039215 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

RAVR2_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.042815 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TPD6	Gene names	Raver2, Kiaa1579
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 2 (Protein raver-2).

T2FA_HUMAN
θ value	0.279714 (rank : 28)	NC score	0.073202 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

CD2L2_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.013412 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	1439	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

BRWD1_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.022430 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	478	Shared Neighborhood Hits	21
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CD2L1_MOUSE
θ value	0.47712 (rank : 31)	NC score	0.012541 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	1463	Shared Neighborhood Hits	28
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

PCLO_MOUSE
θ value	0.47712 (rank : 32)	NC score	0.027781 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	2275	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

DMP1_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.063571 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

RP1L1_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.034939 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	1072	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ATX7_MOUSE
θ value	0.813845 (rank : 35)	NC score	0.035353 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	328	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CD2L1_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.012326 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	1467	Shared Neighborhood Hits	29
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

DSPP_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.062247 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	645	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LEO1_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.058383 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	958	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PP2CG_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.032070 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

SFRS4_MOUSE
θ value	0.813845 (rank : 40)	NC score	0.042362 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	406	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TIAM1_MOUSE
θ value	0.813845 (rank : 41)	NC score	0.021499 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

E41L2_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.022545 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	459	Shared Neighborhood Hits	29
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

NP1L3_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.030451 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

THOC2_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.049956 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	337	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

AXN2_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.020073 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

ICAL_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.040799 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

REXO4_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.030792 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

RHG06_MOUSE
θ value	1.38821 (rank : 48)	NC score	0.022898 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

TCOF_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.039607 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CEP41_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.067360 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99NF3, Q8BT53	Gene names	Tsga14
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

IRS2_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.035493 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

NPBL_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.058451 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SH2D3_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.019285 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SLK_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.006896 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	1798	Shared Neighborhood Hits	35
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SMC2_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.015662 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	1405	Shared Neighborhood Hits	42
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

THYG_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.014670 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

ZC313_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.040368 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	772	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CEP41_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.057603 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYV8, Q7Z496, Q86TM1, Q8NFU8, Q9H6A3, Q9NPV3	Gene names	TSGA14, CEP41
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

CL025_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.046608 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

IP3KC_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.036845 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

LZTS1_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.013558 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	532	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

SRRM2_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.039801 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	1296	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	2.36792 (rank : 63)	NC score	0.042624 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

AFF1_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.046147 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CHD3_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.026030 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	397	Shared Neighborhood Hits	15
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CUBN_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.004883 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	477	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DMP1_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.067837 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	491	Shared Neighborhood Hits	37
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

FARP1_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.012135 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	241	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

K1C20_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.007337 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	468	Shared Neighborhood Hits	8
SwissProt Accessions	P35900	Gene names	KRT20
Domain Architecture
Description	Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT).

NIPBL_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.057470 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	1311	Shared Neighborhood Hits	60
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

R51A1_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.035651 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

SAC3_MOUSE
θ value	3.0926 (rank : 72)	NC score	0.019878 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WF7, Q6A092	Gene names	Sac3, Kiaa0274
Domain Architecture	No domain graphic available
Description	SAC domain-containing protein 3.

TSKS_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.023191 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

UBP31_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.024435 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	293	Shared Neighborhood Hits	20
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

WASF3_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.033070 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

ZN592_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.010086 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	762	Shared Neighborhood Hits	9
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

ARI5B_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.021286 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

BTBD7_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.021762 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

CCD50_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.021869 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CD2AP_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.009502 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	336	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CE290_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.008701 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	1553	Shared Neighborhood Hits	27
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CGRE1_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.028869 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

EHMT1_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.006600 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	417	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

IRS2_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.030141 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	262	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

PARM1_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.027527 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

RHG06_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.020343 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

AFF4_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.046618 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	611	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AIOL_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.000066 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	739	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKT9, Q8WWQ9, Q8WWR0, Q8WWR1, Q8WWR2, Q8WWR3	Gene names	IKZF3, ZNFN1A3
Domain Architecture	No domain graphic available
Description	Zinc finger protein Aiolos (IKAROS family zinc finger protein 3).

BARH2_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.003781 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

CEBPZ_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.017900 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

FNDC3_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.007290 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

HS90B_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.025166 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90B_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.024877 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	98	Shared Neighborhood Hits	8
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

LIPB2_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.009497 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	570	Shared Neighborhood Hits	12
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

RBM15_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.018902 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	309	Shared Neighborhood Hits	15
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

RTN1_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.018044 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

SRCA_MOUSE
θ value	5.27518 (rank : 97)	NC score	0.022700 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	212	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TRDN_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.027819 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	542	Shared Neighborhood Hits	21
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

WASL_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.019207 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	339	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZCH10_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.037478 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	123	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

ZCH14_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.040886 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

AFF1_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.036869 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	23
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CD008_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.019946 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	330	Shared Neighborhood Hits	13
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

DZIP1_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.012724 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	530	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

FBX43_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.017624 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

GAGD4_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.013068 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WTP9, Q5JS82, Q8WYS9	Gene names	XAGE3, GAGED4, PLAC6
Domain Architecture
Description	G antigen family D member 4 (Placenta-specific gene 6 protein) (Protein XAGE-3).

HIPK3_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.005697 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	867	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HS90A_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.024599 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	144	Shared Neighborhood Hits	11
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90A_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.024235 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

IRS1_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.024416 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

K0494_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.014902 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	241	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

MADCA_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.017786 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	221	Shared Neighborhood Hits	7
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAST2_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.002244 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	1110	Shared Neighborhood Hits	17
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PCLO_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.026179 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	2046	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

S30BP_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.019520 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q02614, Q8VDJ5	Gene names	Sap30bp, Hcngp
Domain Architecture	No domain graphic available
Description	SAP30-binding protein (Transcriptional regulator protein HCNGP).

SRCA_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.022078 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	380	Shared Neighborhood Hits	22
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

WASL_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.018194 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZN403_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.016399 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SV77, Q5SV75, Q5SV76, Q5SV78, Q6GVH6, Q6P9J4, Q920N4	Gene names	Znf403, Ggnbp2, Zfp403
Domain Architecture	No domain graphic available
Description	Protein ZNF403 (Gametogenetin-binding protein 2) (Dioxin-inducible factor 3) (DIF-3).

AP3B1_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.017886 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	302	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

BPTF_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.017909 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	786	Shared Neighborhood Hits	31
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CAC1G_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.008469 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	587	Shared Neighborhood Hits	26
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CCNB3_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.009907 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	211	Shared Neighborhood Hits	9
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

DYH5_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.007627 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

LMBTL_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.009316 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y468, Q5H8Y8, Q8IUV7, Q9H1E6, Q9H1G5, Q9UG06, Q9UJB9, Q9Y4C9	Gene names	L3MBTL, KIAA0681, L3MBT
Domain Architecture
Description	Lethal(3)malignant brain tumor-like protein (L(3)mbt-like) (L(3)mbt protein homolog) (H-l(3)mbt protein) (H-L(3)MBT) (L3MBTL1).

M3K3_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.002532 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	876	Shared Neighborhood Hits	14
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

MACF1_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.004387 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	1313	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MYCD_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.009502 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

NUCL_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.011939 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	425	Shared Neighborhood Hits	14
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

TACC3_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.009199 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	779	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

WNK1_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.003805 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	1179	Shared Neighborhood Hits	25
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ZBT40_HUMAN
θ value	8.99809 (rank : 131)	NC score	-0.001015 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	949	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

IWS1_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.050917 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	1258	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TGON2_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.051561 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	1037	Shared Neighborhood Hits	59
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

Hits sorted by NC score

PMS2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PMS2_MOUSE
NC score	0.959278 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

MLH1_HUMAN
NC score	0.743396 (rank : 3)	θ value	3.61106e-41 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

MLH1_MOUSE
NC score	0.740578 (rank : 4)	θ value	6.15952e-41 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JK91, Q62454	Gene names	Mlh1
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

PMS1_HUMAN
NC score	0.700437 (rank : 5)	θ value	6.58091e-43 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

MLH3_HUMAN
NC score	0.568280 (rank : 6)	θ value	6.85773e-16 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

DSPP_MOUSE
NC score	0.081882 (rank : 7)	θ value	0.0330416 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CJ078_MOUSE
NC score	0.078164 (rank : 8)	θ value	0.00869519 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	559	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

LPIN2_HUMAN
NC score	0.077323 (rank : 9)	θ value	0.0193708 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

CD19_HUMAN
NC score	0.074530 (rank : 10)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	P15391, Q96S68, Q9BRD6	Gene names	CD19
Domain Architecture
Description	B-lymphocyte antigen CD19 precursor (Differentiation antigen CD19) (B- lymphocyte surface antigen B4) (Leu-12).

LPIN2_MOUSE
NC score	0.073685 (rank : 11)	θ value	0.00390308 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PI5, Q8C357, Q8C7I8, Q8CC85, Q8CHR7	Gene names	Lpin2
Domain Architecture
Description	Lipin-2.

T2FA_HUMAN
NC score	0.073202 (rank : 12)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

DMP1_HUMAN
NC score	0.067837 (rank : 13)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	491	Shared Neighborhood Hits	37
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

CEP41_MOUSE
NC score	0.067360 (rank : 14)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99NF3, Q8BT53	Gene names	Tsga14
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

UBP34_MOUSE
NC score	0.066808 (rank : 15)	θ value	0.0193708 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.065695 (rank : 16)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	210	Shared Neighborhood Hits	18
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

FILA_HUMAN
NC score	0.065364 (rank : 17)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	685	Shared Neighborhood Hits	44
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

DMP1_MOUSE
NC score	0.063571 (rank : 18)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_HUMAN
NC score	0.062247 (rank : 19)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	645	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ZCH14_MOUSE
NC score	0.060589 (rank : 20)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

AFF4_MOUSE
NC score	0.059350 (rank : 21)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	581	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CHD9_HUMAN
NC score	0.059218 (rank : 22)	θ value	0.0113563 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

NPBL_MOUSE
NC score	0.058451 (rank : 23)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

LEO1_HUMAN
NC score	0.058383 (rank : 24)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	958	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CEP41_HUMAN
NC score	0.057603 (rank : 25)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYV8, Q7Z496, Q86TM1, Q8NFU8, Q9H6A3, Q9NPV3	Gene names	TSGA14, CEP41
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

NIPBL_HUMAN
NC score	0.057470 (rank : 26)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	1311	Shared Neighborhood Hits	60
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ENL_HUMAN
NC score	0.057230 (rank : 27)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	305	Shared Neighborhood Hits	19
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

ZCPW1_MOUSE
NC score	0.055883 (rank : 28)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

TGON2_HUMAN
NC score	0.051561 (rank : 29)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	1037	Shared Neighborhood Hits	59
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

IWS1_MOUSE
NC score	0.050917 (rank : 30)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	1258	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CHD9_MOUSE
NC score	0.050872 (rank : 31)	θ value	0.0113563 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

THOC2_HUMAN
NC score	0.049956 (rank : 32)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	337	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

IP3KC_MOUSE
NC score	0.049297 (rank : 33)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

AFF4_HUMAN
NC score	0.046618 (rank : 34)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	611	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CL025_HUMAN
NC score	0.046608 (rank : 35)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

AFF1_HUMAN
NC score	0.046147 (rank : 36)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

WASF3_MOUSE
NC score	0.043538 (rank : 37)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

RAVR2_MOUSE
NC score	0.042815 (rank : 38)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TPD6	Gene names	Raver2, Kiaa1579
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 2 (Protein raver-2).

SRRM2_MOUSE
NC score	0.042624 (rank : 39)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SFRS4_MOUSE
NC score	0.042362 (rank : 40)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	406	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

ZCH14_HUMAN
NC score	0.040886 (rank : 41)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ICAL_HUMAN
NC score	0.040799 (rank : 42)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ZC313_HUMAN
NC score	0.040368 (rank : 43)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	772	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

SRRM2_HUMAN
NC score	0.039801 (rank : 44)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	1296	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TCOF_HUMAN
NC score	0.039607 (rank : 45)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

MUC13_MOUSE
NC score	0.039215 (rank : 46)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ZCH10_HUMAN
NC score	0.037478 (rank : 47)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	123	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

AFF1_MOUSE
NC score	0.036869 (rank : 48)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	23
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

IP3KC_HUMAN
NC score	0.036845 (rank : 49)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

R51A1_MOUSE
NC score	0.035651 (rank : 50)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

IRS2_MOUSE
NC score	0.035493 (rank : 51)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

ATX7_MOUSE
NC score	0.035353 (rank : 52)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	328	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

RP1L1_HUMAN
NC score	0.034939 (rank : 53)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	1072	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

WASF3_HUMAN
NC score	0.033070 (rank : 54)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

PP2CG_MOUSE
NC score	0.032070 (rank : 55)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

REXO4_MOUSE
NC score	0.030792 (rank : 56)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

NP1L3_HUMAN
NC score	0.030451 (rank : 57)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

IRS2_HUMAN
NC score	0.030141 (rank : 58)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	262	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

CGRE1_MOUSE
NC score	0.028869 (rank : 59)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

TXLNG_HUMAN
NC score	0.028439 (rank : 60)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	568	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

TRDN_HUMAN
NC score	0.027819 (rank : 61)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	542	Shared Neighborhood Hits	21
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

PCLO_MOUSE
NC score	0.027781 (rank : 62)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	2275	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PARM1_HUMAN
NC score	0.027527 (rank : 63)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PCLO_HUMAN
NC score	0.026179 (rank : 64)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	2046	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CHD3_HUMAN
NC score	0.026030 (rank : 65)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	397	Shared Neighborhood Hits	15
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

HS90B_HUMAN
NC score	0.025166 (rank : 66)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90B_MOUSE
NC score	0.024877 (rank : 67)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	98	Shared Neighborhood Hits	8
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

HS90A_HUMAN
NC score	0.024599 (rank : 68)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	144	Shared Neighborhood Hits	11
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

UBP31_HUMAN
NC score	0.024435 (rank : 69)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	293	Shared Neighborhood Hits	20
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

MAGC1_HUMAN
NC score	0.024416 (rank : 70)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	431	Shared Neighborhood Hits	14
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

IRS1_MOUSE
NC score	0.024416 (rank : 71)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

HS90A_MOUSE
NC score	0.024235 (rank : 72)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

TSKS_MOUSE
NC score	0.023191 (rank : 73)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

RHG06_MOUSE
NC score	0.022898 (rank : 74)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SRCA_MOUSE
NC score	0.022700 (rank : 75)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	212	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

E41L2_MOUSE
NC score	0.022545 (rank : 76)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	459	Shared Neighborhood Hits	29
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

BRWD1_MOUSE
NC score	0.022430 (rank : 77)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	478	Shared Neighborhood Hits	21
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

SRCA_HUMAN
NC score	0.022078 (rank : 78)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	380	Shared Neighborhood Hits	22
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

CCD50_MOUSE
NC score	0.021869 (rank : 79)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

BTBD7_MOUSE
NC score	0.021762 (rank : 80)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

TIAM1_MOUSE
NC score	0.021499 (rank : 81)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ARI5B_MOUSE
NC score	0.021286 (rank : 82)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

RHG06_HUMAN
NC score	0.020343 (rank : 83)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

AXN2_HUMAN
NC score	0.020073 (rank : 84)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

CD008_HUMAN
NC score	0.019946 (rank : 85)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	330	Shared Neighborhood Hits	13
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

SAC3_MOUSE
NC score	0.019878 (rank : 86)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WF7, Q6A092	Gene names	Sac3, Kiaa0274
Domain Architecture	No domain graphic available
Description	SAC domain-containing protein 3.

S30BP_MOUSE
NC score	0.019520 (rank : 87)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q02614, Q8VDJ5	Gene names	Sap30bp, Hcngp
Domain Architecture	No domain graphic available
Description	SAP30-binding protein (Transcriptional regulator protein HCNGP).

SH2D3_HUMAN
NC score	0.019285 (rank : 88)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

WASL_MOUSE
NC score	0.019207 (rank : 89)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	339	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RBM15_HUMAN
NC score	0.018902 (rank : 90)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	309	Shared Neighborhood Hits	15
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

WASL_HUMAN
NC score	0.018194 (rank : 91)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RTN1_MOUSE
NC score	0.018044 (rank : 92)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

BPTF_HUMAN
NC score	0.017909 (rank : 93)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	786	Shared Neighborhood Hits	31
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CEBPZ_HUMAN
NC score	0.017900 (rank : 94)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

AP3B1_MOUSE
NC score	0.017886 (rank : 95)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	302	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

MADCA_HUMAN
NC score	0.017786 (rank : 96)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	221	Shared Neighborhood Hits	7
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

FBX43_MOUSE
NC score	0.017624 (rank : 97)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

ZN403_MOUSE
NC score	0.016399 (rank : 98)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SV77, Q5SV75, Q5SV76, Q5SV78, Q6GVH6, Q6P9J4, Q920N4	Gene names	Znf403, Ggnbp2, Zfp403
Domain Architecture	No domain graphic available
Description	Protein ZNF403 (Gametogenetin-binding protein 2) (Dioxin-inducible factor 3) (DIF-3).

SMC2_HUMAN
NC score	0.015662 (rank : 99)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	1405	Shared Neighborhood Hits	42
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

K0494_MOUSE
NC score	0.014902 (rank : 100)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	241	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

THYG_HUMAN
NC score	0.014670 (rank : 101)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

ZN592_MOUSE
NC score	0.013724 (rank : 102)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	768	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

LZTS1_HUMAN
NC score	0.013558 (rank : 103)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	532	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

CD2L2_HUMAN
NC score	0.013412 (rank : 104)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	1439	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

GAGD4_HUMAN
NC score	0.013068 (rank : 105)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WTP9, Q5JS82, Q8WYS9	Gene names	XAGE3, GAGED4, PLAC6
Domain Architecture
Description	G antigen family D member 4 (Placenta-specific gene 6 protein) (Protein XAGE-3).

DZIP1_MOUSE
NC score	0.012724 (rank : 106)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	530	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

CD2L1_MOUSE
NC score	0.012541 (rank : 107)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	1463	Shared Neighborhood Hits	28
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CD2L1_HUMAN
NC score	0.012326 (rank : 108)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	1467	Shared Neighborhood Hits	29
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

FARP1_HUMAN
NC score	0.012135 (rank : 109)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	241	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

NUCL_MOUSE
NC score	0.011939 (rank : 110)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	425	Shared Neighborhood Hits	14
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

ZN592_HUMAN
NC score	0.010086 (rank : 111)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	762	Shared Neighborhood Hits	9
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

CCNB3_MOUSE
NC score	0.009907 (rank : 112)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	211	Shared Neighborhood Hits	9
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

MYCD_MOUSE
NC score	0.009502 (rank : 113)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

CD2AP_MOUSE
NC score	0.009502 (rank : 114)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	336	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

LIPB2_MOUSE
NC score	0.009497 (rank : 115)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	570	Shared Neighborhood Hits	12
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

LMBTL_HUMAN
NC score	0.009316 (rank : 116)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y468, Q5H8Y8, Q8IUV7, Q9H1E6, Q9H1G5, Q9UG06, Q9UJB9, Q9Y4C9	Gene names	L3MBTL, KIAA0681, L3MBT
Domain Architecture
Description	Lethal(3)malignant brain tumor-like protein (L(3)mbt-like) (L(3)mbt protein homolog) (H-l(3)mbt protein) (H-L(3)MBT) (L3MBTL1).

TACC3_HUMAN
NC score	0.009199 (rank : 117)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	779	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CE290_HUMAN
NC score	0.008701 (rank : 118)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	1553	Shared Neighborhood Hits	27
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CAC1G_HUMAN
NC score	0.008469 (rank : 119)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	587	Shared Neighborhood Hits	26
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

DYH5_MOUSE
NC score	0.007627 (rank : 120)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

K1C20_HUMAN
NC score	0.007337 (rank : 121)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	468	Shared Neighborhood Hits	8
SwissProt Accessions	P35900	Gene names	KRT20
Domain Architecture
Description	Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT).

FNDC3_HUMAN
NC score	0.007290 (rank : 122)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

SLK_MOUSE
NC score	0.006896 (rank : 123)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	1798	Shared Neighborhood Hits	35
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

EHMT1_HUMAN
NC score	0.006600 (rank : 124)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	417	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

HIPK3_HUMAN
NC score	0.005697 (rank : 125)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	867	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

CUBN_MOUSE
NC score	0.004883 (rank : 126)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	477	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

MACF1_MOUSE
NC score	0.004387 (rank : 127)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	1313	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

WNK1_MOUSE
NC score	0.003805 (rank : 128)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	1179	Shared Neighborhood Hits	25
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

BARH2_HUMAN
NC score	0.003781 (rank : 129)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

M3K3_MOUSE
NC score	0.002532 (rank : 130)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	876	Shared Neighborhood Hits	14
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

MAST2_MOUSE
NC score	0.002244 (rank : 131)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	1110	Shared Neighborhood Hits	17
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

AIOL_HUMAN
NC score	0.000066 (rank : 132)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	739	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKT9, Q8WWQ9, Q8WWR0, Q8WWR1, Q8WWR2, Q8WWR3	Gene names	IKZF3, ZNFN1A3
Domain Architecture	No domain graphic available
Description	Zinc finger protein Aiolos (IKAROS family zinc finger protein 3).

ZBT40_HUMAN
NC score	-0.001015 (rank : 133)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	949	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.