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Network neighborhood for query Sequence : HS90B_HUMAN

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HS90B_HUMAN
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HS90A_HUMAN
θ value	0 (rank : 1)	NC score	0.977168 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	144	Shared Neighborhood Hits	49
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90A_MOUSE
θ value	0 (rank : 2)	NC score	0.979917 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	155	Shared Neighborhood Hits	50
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

HS90B_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90B_MOUSE
θ value	0 (rank : 4)	NC score	0.998135 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

ENPL_HUMAN
θ value	2.6227e-108 (rank : 5)	NC score	0.933458 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

ENPL_MOUSE
θ value	2.89973e-107 (rank : 6)	NC score	0.931922 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

TRAP1_HUMAN
θ value	5.55816e-50 (rank : 7)	NC score	0.856840 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

TRAP1_MOUSE
θ value	2.1121e-49 (rank : 8)	NC score	0.855764 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

SEC63_HUMAN
θ value	0.0148317 (rank : 9)	NC score	0.108499 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	586	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

TRIPB_HUMAN
θ value	0.0148317 (rank : 10)	NC score	0.038416 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	1587	Shared Neighborhood Hits	42
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

KI67_HUMAN
θ value	0.0330416 (rank : 11)	NC score	0.060042 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	581	Shared Neighborhood Hits	17
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

SEC63_MOUSE
θ value	0.0330416 (rank : 12)	NC score	0.101651 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	601	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

CND3_HUMAN
θ value	0.0961366 (rank : 13)	NC score	0.080253 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BPX3, Q96SV9, Q9BUR3, Q9BVY1, Q9H914, Q9H9Z6, Q9HBI9	Gene names	NCAPG, CAPG, NYMEL3
Domain Architecture
Description	Condensin complex subunit 3 (Non-SMC condensin I complex subunit G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (XCAP-G homolog) (Antigen NY-MEL-3).

NUF2_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.036815 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	661	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

PRI1_MOUSE
θ value	0.21417 (rank : 15)	NC score	0.091735 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

SMC2_HUMAN
θ value	0.21417 (rank : 16)	NC score	0.035334 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	1405	Shared Neighborhood Hits	41
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

HSF2B_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.144641 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	104	Shared Neighborhood Hits	14
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

LAMA2_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.016235 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	1198	Shared Neighborhood Hits	25
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

OXSR1_MOUSE
θ value	0.365318 (rank : 19)	NC score	0.012383 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	865	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

SYNE1_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.028237 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	1484	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

AT10A_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.022481 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	O60312, Q969I4	Gene names	ATP10A, ATP10C, ATPVC, KIAA0566
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPVA) (Aminophospholipid translocase VA).

RELN_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.036019 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

EVI1_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.002959 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	924	Shared Neighborhood Hits	17
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

OXSR1_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.011040 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	874	Shared Neighborhood Hits	9
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

BAZ1A_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.023659 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CCD46_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.023349 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	1405	Shared Neighborhood Hits	36
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

KIF5A_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.017530 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	859	Shared Neighborhood Hits	30
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

DYH11_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.023981 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	234	Shared Neighborhood Hits	15
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

BPAEA_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.022284 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	1369	Shared Neighborhood Hits	33
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CEP55_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.025713 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CLC6A_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.013102 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EIG7	Gene names	CLEC6A, CLECSF10, DECTIN2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

LEO1_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.045057 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	958	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

TCAL5_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.033505 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	806	Shared Neighborhood Hits	26
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ANLN_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.034749 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

BPA1_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.018562 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	1477	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD46_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.021550 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	1430	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CK5P2_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.016948 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	1433	Shared Neighborhood Hits	36
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

IWS1_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.017189 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	1258	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.048149 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	946	Shared Neighborhood Hits	35
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NAF1_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.024844 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	937	Shared Neighborhood Hits	31
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

RGS6_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.012383 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

SMC2_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.035887 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	1131	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SMRC2_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.028817 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	499	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TXND2_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.034898 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	828	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZA2G_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.007738 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q64726	Gene names	Azgp1
Domain Architecture
Description	Zinc-alpha-2-glycoprotein precursor (Zn-alpha-2-glycoprotein) (Zn- alpha-2-GP).

ZBT24_HUMAN
θ value	3.0926 (rank : 46)	NC score	-0.000210 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	870	Shared Neighborhood Hits	7
SwissProt Accessions	O43167, Q5TED5, Q8N455	Gene names	ZBTB24, KIAA0441, ZNF450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450).

CJ092_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.031205 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYW2, Q5JSF7, Q9NTQ5	Gene names	C10orf92
Domain Architecture	No domain graphic available
Description	Protein C10orf92.

NOC2L_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.025225 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3T9, Q5SVA3, Q9BTN6	Gene names	NOC2L
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

NSBP1_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.037316 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	681	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

ST1E1_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.022705 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P49888, Q8N6X5	Gene names	SULT1E1, STE
Domain Architecture
Description	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen- preferring) (EST-1).

STK39_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.007045 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	882	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

STK39_MOUSE
θ value	4.03905 (rank : 52)	NC score	0.007667 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	915	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

ADA30_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.014589 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	391	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

AT10A_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.013063 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	O54827, Q8R3B8	Gene names	Atp10a, Atpc5, Pfatp
Domain Architecture
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (P-locus fat-associated ATPase).

MAP1A_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.027969 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MPIP3_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.029898 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

MRIP_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.026513 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	578	Shared Neighborhood Hits	23
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.026903 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	569	Shared Neighborhood Hits	25
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

PHF3_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.035032 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	21
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PITX2_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.010583 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	381	Shared Neighborhood Hits	8
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

PMS2_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.025166 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	131	Shared Neighborhood Hits	9
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

S12A6_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.013577 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A6_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.013552 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

TARA_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.025319 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	1133	Shared Neighborhood Hits	28
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TGON1_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.023082 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	243	Shared Neighborhood Hits	13
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TRI36_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.004983 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

ZN318_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.037682 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	642	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

AFF4_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.013666 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	611	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ANLN_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.036384 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	297	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANR11_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.018412 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	1289	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

DCDC2_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.019915 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

DESP_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.018338 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	1470	Shared Neighborhood Hits	42
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DYH9_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.023809 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	291	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

IF4G3_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.015343 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.015480 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

KIF5C_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.014426 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	974	Shared Neighborhood Hits	28
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LMO7_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.019868 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	507	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MPP8_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.024690 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	948	Shared Neighborhood Hits	34
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NKX61_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.004050 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

P52K_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.021524 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

SALL1_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.001178 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	826	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

SC10A_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.003020 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SMRC2_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.027975 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	487	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SYCP1_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.028161 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	1456	Shared Neighborhood Hits	38
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TEX14_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.007599 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	1333	Shared Neighborhood Hits	29
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TTC1_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.015123 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	13
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

ABCG2_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.003495 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

ANR26_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.011855 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	1554	Shared Neighborhood Hits	34
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CP135_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.016702 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	1290	Shared Neighborhood Hits	37
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DMP1_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.019997 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

FIBP_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.020119 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI19	Gene names	Fibp
Domain Architecture
Description	Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein).

NKX61_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.003674 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	431	Shared Neighborhood Hits	8
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

PEG3_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.007640 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	1101	Shared Neighborhood Hits	20
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PITX2_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.007368 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	383	Shared Neighborhood Hits	8
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

RELN_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.025495 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RXINP_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.019831 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

SHOX_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.006950 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	363	Shared Neighborhood Hits	8
SwissProt Accessions	O15266, O00412, O00413, O15267	Gene names	SHOX, PHOG
Domain Architecture
Description	Short stature homeobox protein (Short stature homeobox-containing protein) (Pseudoautosomal homeobox-containing osteogenic protein).

TGON2_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.015611 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	277	Shared Neighborhood Hits	13
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

Hits sorted by NC score

HS90B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90B_MOUSE
NC score	0.998135 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

HS90A_MOUSE
NC score	0.979917 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	155	Shared Neighborhood Hits	50
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

HS90A_HUMAN
NC score	0.977168 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	144	Shared Neighborhood Hits	49
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

ENPL_HUMAN
NC score	0.933458 (rank : 5)	θ value	2.6227e-108 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

ENPL_MOUSE
NC score	0.931922 (rank : 6)	θ value	2.89973e-107 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

TRAP1_HUMAN
NC score	0.856840 (rank : 7)	θ value	5.55816e-50 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

TRAP1_MOUSE
NC score	0.855764 (rank : 8)	θ value	2.1121e-49 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

HSF2B_HUMAN
NC score	0.144641 (rank : 9)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	104	Shared Neighborhood Hits	14
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

SEC63_HUMAN
NC score	0.108499 (rank : 10)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	586	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
NC score	0.101651 (rank : 11)	θ value	0.0330416 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	601	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

PRI1_MOUSE
NC score	0.091735 (rank : 12)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

CND3_HUMAN
NC score	0.080253 (rank : 13)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BPX3, Q96SV9, Q9BUR3, Q9BVY1, Q9H914, Q9H9Z6, Q9HBI9	Gene names	NCAPG, CAPG, NYMEL3
Domain Architecture
Description	Condensin complex subunit 3 (Non-SMC condensin I complex subunit G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (XCAP-G homolog) (Antigen NY-MEL-3).

KI67_HUMAN
NC score	0.060042 (rank : 14)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	581	Shared Neighborhood Hits	17
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LEO1_MOUSE
NC score	0.048149 (rank : 15)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	946	Shared Neighborhood Hits	35
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.045057 (rank : 16)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	958	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

TRIPB_HUMAN
NC score	0.038416 (rank : 17)	θ value	0.0148317 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	1587	Shared Neighborhood Hits	42
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ZN318_MOUSE
NC score	0.037682 (rank : 18)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	642	Shared Neighborhood Hits	33
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

NSBP1_MOUSE
NC score	0.037316 (rank : 19)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	681	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NUF2_HUMAN
NC score	0.036815 (rank : 20)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	661	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

ANLN_MOUSE
NC score	0.036384 (rank : 21)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	297	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

RELN_HUMAN
NC score	0.036019 (rank : 22)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

SMC2_MOUSE
NC score	0.035887 (rank : 23)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	1131	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SMC2_HUMAN
NC score	0.035334 (rank : 24)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	1405	Shared Neighborhood Hits	41
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

PHF3_HUMAN
NC score	0.035032 (rank : 25)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	21
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

TXND2_MOUSE
NC score	0.034898 (rank : 26)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	828	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ANLN_HUMAN
NC score	0.034749 (rank : 27)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

TCAL5_HUMAN
NC score	0.033505 (rank : 28)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	806	Shared Neighborhood Hits	26
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CJ092_HUMAN
NC score	0.031205 (rank : 29)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYW2, Q5JSF7, Q9NTQ5	Gene names	C10orf92
Domain Architecture	No domain graphic available
Description	Protein C10orf92.

MPIP3_HUMAN
NC score	0.029898 (rank : 30)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

SMRC2_HUMAN
NC score	0.028817 (rank : 31)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	499	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SYNE1_HUMAN
NC score	0.028237 (rank : 32)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	1484	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYCP1_MOUSE
NC score	0.028161 (rank : 33)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	1456	Shared Neighborhood Hits	38
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SMRC2_MOUSE
NC score	0.027975 (rank : 34)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	487	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

MAP1A_HUMAN
NC score	0.027969 (rank : 35)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MRIP_MOUSE
NC score	0.026903 (rank : 36)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	569	Shared Neighborhood Hits	25
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MRIP_HUMAN
NC score	0.026513 (rank : 37)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	578	Shared Neighborhood Hits	23
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

CEP55_MOUSE
NC score	0.025713 (rank : 38)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

RELN_MOUSE
NC score	0.025495 (rank : 39)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

TARA_MOUSE
NC score	0.025319 (rank : 40)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	1133	Shared Neighborhood Hits	28
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NOC2L_HUMAN
NC score	0.025225 (rank : 41)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3T9, Q5SVA3, Q9BTN6	Gene names	NOC2L
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

PMS2_HUMAN
NC score	0.025166 (rank : 42)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	131	Shared Neighborhood Hits	9
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

NAF1_HUMAN
NC score	0.024844 (rank : 43)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	937	Shared Neighborhood Hits	31
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

MPP8_HUMAN
NC score	0.024690 (rank : 44)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	948	Shared Neighborhood Hits	34
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

DYH11_HUMAN
NC score	0.023981 (rank : 45)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	234	Shared Neighborhood Hits	15
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

DYH9_HUMAN
NC score	0.023809 (rank : 46)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	291	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

BAZ1A_HUMAN
NC score	0.023659 (rank : 47)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CCD46_MOUSE
NC score	0.023349 (rank : 48)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	1405	Shared Neighborhood Hits	36
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

TGON1_MOUSE
NC score	0.023082 (rank : 49)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	243	Shared Neighborhood Hits	13
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

ST1E1_HUMAN
NC score	0.022705 (rank : 50)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P49888, Q8N6X5	Gene names	SULT1E1, STE
Domain Architecture
Description	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen- preferring) (EST-1).

AT10A_HUMAN
NC score	0.022481 (rank : 51)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	O60312, Q969I4	Gene names	ATP10A, ATP10C, ATPVC, KIAA0566
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPVA) (Aminophospholipid translocase VA).

BPAEA_HUMAN
NC score	0.022284 (rank : 52)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	1369	Shared Neighborhood Hits	33
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD46_HUMAN
NC score	0.021550 (rank : 53)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	1430	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

P52K_HUMAN
NC score	0.021524 (rank : 54)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

FIBP_MOUSE
NC score	0.020119 (rank : 55)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI19	Gene names	Fibp
Domain Architecture
Description	Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein).

DMP1_HUMAN
NC score	0.019997 (rank : 56)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DCDC2_HUMAN
NC score	0.019915 (rank : 57)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

LMO7_HUMAN
NC score	0.019868 (rank : 58)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	507	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

RXINP_HUMAN
NC score	0.019831 (rank : 59)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

BPA1_MOUSE
NC score	0.018562 (rank : 60)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	1477	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ANR11_HUMAN
NC score	0.018412 (rank : 61)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	1289	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

DESP_HUMAN
NC score	0.018338 (rank : 62)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	1470	Shared Neighborhood Hits	42
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

KIF5A_MOUSE
NC score	0.017530 (rank : 63)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	859	Shared Neighborhood Hits	30
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

IWS1_MOUSE
NC score	0.017189 (rank : 64)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	1258	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CK5P2_HUMAN
NC score	0.016948 (rank : 65)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	1433	Shared Neighborhood Hits	36
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CP135_HUMAN
NC score	0.016702 (rank : 66)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	1290	Shared Neighborhood Hits	37
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

LAMA2_MOUSE
NC score	0.016235 (rank : 67)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	1198	Shared Neighborhood Hits	25
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

TGON2_MOUSE
NC score	0.015611 (rank : 68)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	277	Shared Neighborhood Hits	13
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

IF4G3_MOUSE
NC score	0.015480 (rank : 69)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_HUMAN
NC score	0.015343 (rank : 70)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

TTC1_HUMAN
NC score	0.015123 (rank : 71)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	13
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

ADA30_HUMAN
NC score	0.014589 (rank : 72)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	391	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

KIF5C_HUMAN
NC score	0.014426 (rank : 73)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	974	Shared Neighborhood Hits	28
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

AFF4_HUMAN
NC score	0.013666 (rank : 74)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	611	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

S12A6_HUMAN
NC score	0.013577 (rank : 75)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A6_MOUSE
NC score	0.013552 (rank : 76)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

CLC6A_HUMAN
NC score	0.013102 (rank : 77)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EIG7	Gene names	CLEC6A, CLECSF10, DECTIN2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

AT10A_MOUSE
NC score	0.013063 (rank : 78)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	O54827, Q8R3B8	Gene names	Atp10a, Atpc5, Pfatp
Domain Architecture
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (P-locus fat-associated ATPase).

RGS6_HUMAN
NC score	0.012383 (rank : 79)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

OXSR1_MOUSE
NC score	0.012383 (rank : 80)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	865	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

ANR26_MOUSE
NC score	0.011855 (rank : 81)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	1554	Shared Neighborhood Hits	34
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

OXSR1_HUMAN
NC score	0.011040 (rank : 82)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	874	Shared Neighborhood Hits	9
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

PITX2_HUMAN
NC score	0.010583 (rank : 83)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	381	Shared Neighborhood Hits	8
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

ZA2G_MOUSE
NC score	0.007738 (rank : 84)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q64726	Gene names	Azgp1
Domain Architecture
Description	Zinc-alpha-2-glycoprotein precursor (Zn-alpha-2-glycoprotein) (Zn- alpha-2-GP).

STK39_MOUSE
NC score	0.007667 (rank : 85)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	915	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

PEG3_MOUSE
NC score	0.007640 (rank : 86)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	1101	Shared Neighborhood Hits	20
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

TEX14_MOUSE
NC score	0.007599 (rank : 87)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	1333	Shared Neighborhood Hits	29
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

PITX2_MOUSE
NC score	0.007368 (rank : 88)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	383	Shared Neighborhood Hits	8
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

STK39_HUMAN
NC score	0.007045 (rank : 89)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	882	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

SHOX_HUMAN
NC score	0.006950 (rank : 90)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	363	Shared Neighborhood Hits	8
SwissProt Accessions	O15266, O00412, O00413, O15267	Gene names	SHOX, PHOG
Domain Architecture
Description	Short stature homeobox protein (Short stature homeobox-containing protein) (Pseudoautosomal homeobox-containing osteogenic protein).

TRI36_HUMAN
NC score	0.004983 (rank : 91)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

NKX61_MOUSE
NC score	0.004050 (rank : 92)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NKX61_HUMAN
NC score	0.003674 (rank : 93)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	431	Shared Neighborhood Hits	8
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

ABCG2_MOUSE
NC score	0.003495 (rank : 94)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

SC10A_HUMAN
NC score	0.003020 (rank : 95)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

EVI1_HUMAN
NC score	0.002959 (rank : 96)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	924	Shared Neighborhood Hits	17
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

SALL1_MOUSE
NC score	0.001178 (rank : 97)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	826	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

ZBT24_HUMAN
NC score	-0.000210 (rank : 98)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	870	Shared Neighborhood Hits	7
SwissProt Accessions	O43167, Q5TED5, Q8N455	Gene names	ZBTB24, KIAA0441, ZNF450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450).