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Network neighborhood for query Sequence : NOC2L_HUMAN

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NOC2L_HUMAN
SwissProt Accessions	Q9Y3T9, Q5SVA3, Q9BTN6	Gene names	NOC2L
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NOC2L_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y3T9, Q5SVA3, Q9BTN6	Gene names	NOC2L
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

NOC2L_MOUSE
θ value	0 (rank : 2)	NC score	0.975972 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WV70, Q8VE16	Gene names	Noc2l
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

IWS1_HUMAN
θ value	0.163984 (rank : 3)	NC score	0.047542 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	1241	Shared Neighborhood Hits	18
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.055005 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	958	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

HTSF1_HUMAN
θ value	0.279714 (rank : 5)	NC score	0.057065 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

HOOK1_HUMAN
θ value	0.365318 (rank : 6)	NC score	0.026599 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	942	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

WDR60_MOUSE
θ value	0.365318 (rank : 7)	NC score	0.049918 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	344	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

HOOK1_MOUSE
θ value	0.62314 (rank : 8)	NC score	0.025775 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	910	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

RFIP4_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.027359 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	785	Shared Neighborhood Hits	11
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

LMD1_HUMAN
θ value	1.81305 (rank : 10)	NC score	0.030635 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

CA065_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.026312 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	469	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

IWS1_MOUSE
θ value	2.36792 (rank : 12)	NC score	0.042432 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	1258	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

YTDC1_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.040693 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

CENPK_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.025791 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	273	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

FBX38_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.028374 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

HS90B_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.026067 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

LEO1_MOUSE
θ value	3.0926 (rank : 17)	NC score	0.047702 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	946	Shared Neighborhood Hits	21
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TLK1_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.015211 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	967	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

TLK1_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.015059 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	947	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

ARHGG_MOUSE
θ value	4.03905 (rank : 20)	NC score	0.013511 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CCAR1_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.025432 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	414	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

DHX37_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.014816 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

ELL_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.020212 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	183	Shared Neighborhood Hits	2
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

FYV1_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.025699 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.025948 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

HS90B_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.025225 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

K0555_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.017204 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	880	Shared Neighborhood Hits	10
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

LATS1_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.007698 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	1027	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

TLK2_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.015243 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	1044	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

TLK2_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.015070 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	1088	Shared Neighborhood Hits	12
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

CALL3_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.007793 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

LRRF1_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.024576 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	440	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

NCOR1_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.019747 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

RCOR3_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.019871 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

RFIP4_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.023877 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	708	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

CD2L1_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.007595 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	1467	Shared Neighborhood Hits	19
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L2_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.007674 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	1439	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

ERCC5_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.018602 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

FMNL_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.018160 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	428	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

LATS1_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.006975 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	1057	Shared Neighborhood Hits	11
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

SRBS1_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.011554 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	396	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

UBF1_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.023084 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	415	Shared Neighborhood Hits	10
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

CCD55_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.028656 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	519	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

HMMR_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.008918 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	1082	Shared Neighborhood Hits	14
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

IF39_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.020628 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

RAC3_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.004401 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	233	Shared Neighborhood Hits	3
SwissProt Accessions	P60763, O14658, Q5U0M8	Gene names	RAC3
Domain Architecture
Description	Ras-related C3 botulinum toxin substrate 3 (p21-Rac3).

RAC3_MOUSE
θ value	8.99809 (rank : 47)	NC score	0.004401 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	233	Shared Neighborhood Hits	3
SwissProt Accessions	P60764, O14658	Gene names	Rac3
Domain Architecture
Description	Ras-related C3 botulinum toxin substrate 3 (p21-Rac3).

RCOR3_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.016870 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

RIMB2_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.009794 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

Hits sorted by NC score

NOC2L_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y3T9, Q5SVA3, Q9BTN6	Gene names	NOC2L
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

NOC2L_MOUSE
NC score	0.975972 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WV70, Q8VE16	Gene names	Noc2l
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

HTSF1_HUMAN
NC score	0.057065 (rank : 3)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

LEO1_HUMAN
NC score	0.055005 (rank : 4)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	958	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

WDR60_MOUSE
NC score	0.049918 (rank : 5)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	344	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

LEO1_MOUSE
NC score	0.047702 (rank : 6)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	946	Shared Neighborhood Hits	21
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

IWS1_HUMAN
NC score	0.047542 (rank : 7)	θ value	0.163984 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	1241	Shared Neighborhood Hits	18
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.042432 (rank : 8)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	1258	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

YTDC1_HUMAN
NC score	0.040693 (rank : 9)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

LMD1_HUMAN
NC score	0.030635 (rank : 10)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

CCD55_MOUSE
NC score	0.028656 (rank : 11)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	519	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

FBX38_HUMAN
NC score	0.028374 (rank : 12)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

RFIP4_HUMAN
NC score	0.027359 (rank : 13)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	785	Shared Neighborhood Hits	11
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

HOOK1_HUMAN
NC score	0.026599 (rank : 14)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	942	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

CA065_HUMAN
NC score	0.026312 (rank : 15)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	469	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

HS90B_MOUSE
NC score	0.026067 (rank : 16)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

FYV1_MOUSE
NC score	0.025948 (rank : 17)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

CENPK_HUMAN
NC score	0.025791 (rank : 18)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	273	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

HOOK1_MOUSE
NC score	0.025775 (rank : 19)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	910	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

FYV1_HUMAN
NC score	0.025699 (rank : 20)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

CCAR1_MOUSE
NC score	0.025432 (rank : 21)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	414	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

HS90B_HUMAN
NC score	0.025225 (rank : 22)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

LRRF1_MOUSE
NC score	0.024576 (rank : 23)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	440	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

RFIP4_MOUSE
NC score	0.023877 (rank : 24)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	708	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

UBF1_HUMAN
NC score	0.023084 (rank : 25)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	415	Shared Neighborhood Hits	10
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

IF39_MOUSE
NC score	0.020628 (rank : 26)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

ELL_HUMAN
NC score	0.020212 (rank : 27)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	183	Shared Neighborhood Hits	2
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

RCOR3_MOUSE
NC score	0.019871 (rank : 28)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

NCOR1_HUMAN
NC score	0.019747 (rank : 29)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

ERCC5_HUMAN
NC score	0.018602 (rank : 30)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

FMNL_MOUSE
NC score	0.018160 (rank : 31)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	428	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

K0555_HUMAN
NC score	0.017204 (rank : 32)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	880	Shared Neighborhood Hits	10
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

RCOR3_HUMAN
NC score	0.016870 (rank : 33)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

TLK2_HUMAN
NC score	0.015243 (rank : 34)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	1044	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

TLK1_HUMAN
NC score	0.015211 (rank : 35)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	967	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

TLK2_MOUSE
NC score	0.015070 (rank : 36)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	1088	Shared Neighborhood Hits	12
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

TLK1_MOUSE
NC score	0.015059 (rank : 37)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	947	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C0V0	Gene names	Tlk1
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1).

DHX37_HUMAN
NC score	0.014816 (rank : 38)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

ARHGG_MOUSE
NC score	0.013511 (rank : 39)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

SRBS1_HUMAN
NC score	0.011554 (rank : 40)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	396	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

RIMB2_HUMAN
NC score	0.009794 (rank : 41)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

HMMR_HUMAN
NC score	0.008918 (rank : 42)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	1082	Shared Neighborhood Hits	14
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CALL3_HUMAN
NC score	0.007793 (rank : 43)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

LATS1_MOUSE
NC score	0.007698 (rank : 44)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	1027	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

CD2L2_HUMAN
NC score	0.007674 (rank : 45)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	1439	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CD2L1_HUMAN
NC score	0.007595 (rank : 46)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	1467	Shared Neighborhood Hits	19
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

LATS1_HUMAN
NC score	0.006975 (rank : 47)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	1057	Shared Neighborhood Hits	11
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

RAC3_HUMAN
NC score	0.004401 (rank : 48)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	233	Shared Neighborhood Hits	3
SwissProt Accessions	P60763, O14658, Q5U0M8	Gene names	RAC3
Domain Architecture
Description	Ras-related C3 botulinum toxin substrate 3 (p21-Rac3).

RAC3_MOUSE
NC score	0.004401 (rank : 49)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	233	Shared Neighborhood Hits	3
SwissProt Accessions	P60764, O14658	Gene names	Rac3
Domain Architecture
Description	Ras-related C3 botulinum toxin substrate 3 (p21-Rac3).