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Network neighborhood for query Sequence : S12A6_HUMAN

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S12A6_HUMAN
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

S12A4_HUMAN
θ value	0 (rank : 1)	NC score	0.996905 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UP95, O60632, O75893, Q13953, Q96LD5	Gene names	SLC12A4, KCC1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1).

S12A4_MOUSE
θ value	0 (rank : 2)	NC score	0.996957 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JIS8, O55069, Q9ET57	Gene names	Slc12a4, Kcc1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).

S12A5_HUMAN
θ value	0 (rank : 3)	NC score	0.993246 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

S12A5_MOUSE
θ value	0 (rank : 4)	NC score	0.993142 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

S12A6_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A6_MOUSE
θ value	0 (rank : 6)	NC score	0.999225 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A7_HUMAN
θ value	0 (rank : 7)	NC score	0.993834 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2	Gene names	SLC12A7, KCC4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A7_MOUSE
θ value	0 (rank : 8)	NC score	0.994345 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A3_MOUSE
θ value	1.7238e-59 (rank : 9)	NC score	0.833241 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	P59158	Gene names	Slc12a3, Tsc
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A3_HUMAN
θ value	3.974e-56 (rank : 10)	NC score	0.816516 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	P55017	Gene names	SLC12A3, TSC
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A2_HUMAN
θ value	2.18062e-54 (rank : 11)	NC score	0.807786 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	P55011, Q8N713, Q8WWH7	Gene names	SLC12A2, NKCC1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A2_MOUSE
θ value	2.84797e-54 (rank : 12)	NC score	0.809632 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A1_HUMAN
θ value	3.84914e-51 (rank : 13)	NC score	0.801784 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q13621	Gene names	SLC12A1, NKCC2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter).

S12A1_MOUSE
θ value	1.46268e-50 (rank : 14)	NC score	0.801674 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	P55014, O35938, Q91W55, Q9Z1E0	Gene names	Slc12a1, Nkcc2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (BSC1) (Kidney-specific Na-K-Cl symporter).

CTR2_MOUSE
θ value	0.000270298 (rank : 15)	NC score	0.212208 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P18581	Gene names	Slc7a2, Atrc2, Tea
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (TEA protein) (T-cell early activation protein) (20.5).

CTR2_HUMAN
θ value	0.000461057 (rank : 16)	NC score	0.188325 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P52569	Gene names	SLC7A2, ATRC2
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2).

CTR1_HUMAN
θ value	0.00509761 (rank : 17)	NC score	0.162649 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	P30825	Gene names	SLC7A1, ATRC1, REC1L
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor homolog) (ERR) (Ecotropic retrovirus receptor homolog).

CTR1_MOUSE
θ value	0.0252991 (rank : 18)	NC score	0.177353 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q09143, P30824	Gene names	Slc7a1, Atrc1, Rec-1
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).

AAA1_HUMAN
θ value	0.0431538 (rank : 19)	NC score	0.080837 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NS82	Gene names	SLC7A10, ASC1
Domain Architecture
Description	Asc-type amino acid transporter 1 (Asc-1).

DNMT1_HUMAN
θ value	0.0961366 (rank : 20)	NC score	0.033405 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	401	Shared Neighborhood Hits	9
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

BAT1_MOUSE
θ value	0.125558 (rank : 21)	NC score	0.122116 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXA6	Gene names	Slc7a9, Bat1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

AAA1_MOUSE
θ value	0.163984 (rank : 22)	NC score	0.087389 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P63115, Q9CW25, Q9JMH8	Gene names	Slc7a10, Asc1
Domain Architecture	No domain graphic available
Description	Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).

CTR3_HUMAN
θ value	0.163984 (rank : 23)	NC score	0.147021 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WY07, Q8N185, Q8NCA7, Q96SZ7	Gene names	SLC7A3, ATRC3, CAT3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

BAT1_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.104275 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P82251	Gene names	SLC7A9, BAT1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

CTR3_MOUSE
θ value	0.47712 (rank : 25)	NC score	0.142090 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P70423	Gene names	Slc7a3, Atrc3, Cat3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

KCC2B_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.001116 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	841	Shared Neighborhood Hits	4
SwissProt Accessions	P28652, Q5SVH9	Gene names	Camk2b, Camk2d
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

GOGA4_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.008359 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	2034	Shared Neighborhood Hits	20
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

LAT1_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.061590 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q01650, Q9UBN8, Q9UP15, Q9UQC0	Gene names	SLC7A5, CD98LC, LAT1, MPE16
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain) (Integral membrane protein E16) (hLAT1).

MAP1B_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.018165 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	903	Shared Neighborhood Hits	11
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MYST3_MOUSE
θ value	1.06291 (rank : 30)	NC score	0.012088 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	688	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

HS90A_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.018456 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

PLEC1_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.004147 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	1326	Shared Neighborhood Hits	11
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PMS2_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.014602 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

S36A1_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.033868 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z2H8, Q7Z7C0, Q96M74	Gene names	SLC36A1, PAT1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

COX10_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.024969 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

RM21_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.020263 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2W9	Gene names	MRPL21
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L21, mitochondrial precursor (L21mt) (MRP-L21).

TAOK3_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.000247 (rank : 63)
Query Neighborhood Hits	58	Target Neighborhood Hits	1458	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

DGAT1_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.026871 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	O75907, Q96BB8	Gene names	DGAT1, AGRP1, DGAT
Domain Architecture
Description	Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Diglyceride acyltransferase) (ACAT-related gene product 1).

EDG1_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.004953 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	860	Shared Neighborhood Hits	7
SwissProt Accessions	P21453	Gene names	EDG1
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1).

MAP1B_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.016520 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	977	Shared Neighborhood Hits	11
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NASP_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.016847 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	709	Shared Neighborhood Hits	10
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

DGAT1_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.025089 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2A7, Q9D7Q5	Gene names	Dgat1, Dgat
Domain Architecture
Description	Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Diglyceride acyltransferase).

LAT1_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.057773 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z127, Q9JMI4	Gene names	Slc7a5, Lat1
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC).

RHG09_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.005821 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	186	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

KIF4A_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.002705 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	1033	Shared Neighborhood Hits	9
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

HS90B_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.013577 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

IF3A_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.005078 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	875	Shared Neighborhood Hits	8
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

OR5T1_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.000653 (rank : 62)
Query Neighborhood Hits	58	Target Neighborhood Hits	654	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NG75	Gene names	OR5T1
Domain Architecture	No domain graphic available
Description	Olfactory receptor 5T1 (Olfactory receptor OR11-179).

OR7A2_HUMAN
θ value	5.27518 (rank : 49)	NC score	-0.001616 (rank : 64)
Query Neighborhood Hits	58	Target Neighborhood Hits	782	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NGA2, Q96R95	Gene names	OR7A2, OR7A7
Domain Architecture
Description	Olfactory receptor 7A2.

PRP6_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.016021 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	O94906, O95109, Q5VXS5, Q9H3Z1, Q9H4T9, Q9H4U8, Q9NTE6	Gene names	PRPF6, C20orf14
Domain Architecture
Description	Pre-mRNA-processing factor 6 homolog (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein).

PRP6_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.016012 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YR7, Q8CIK9, Q8R3M8, Q99JN1, Q9CSZ0	Gene names	Prpf6
Domain Architecture
Description	Pre-mRNA-processing factor 6 homolog (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein).

SOAT2_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.018231 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	O75908, Q96TD4, Q9UNR2	Gene names	SOAT2, ACACT2, ACAT2
Domain Architecture
Description	Sterol O-acyltransferase 2 (EC 2.3.1.26) (Cholesterol acyltransferase 2) (Acyl coenzyme A:cholesterol acyltransferase 2) (ACAT-2).

EDG1_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.006512 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	867	Shared Neighborhood Hits	10
SwissProt Accessions	O08530, Q9R235	Gene names	Edg1, Lpb1
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1) (Lysophospholipid receptor B1).

NPT2B_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.008410 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBP0, Q9Z290	Gene names	Slc34a2, Npt2b
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 2B (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2).

G137B_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.049166 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	7
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

P52K_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.006162 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

SNIP_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.010854 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	313	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

STX12_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.004432 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	226	Shared Neighborhood Hits	6
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

CTR4_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.102070 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	O43246, Q3KNQ6, Q4VC45, Q6IBY8, Q96H88	Gene names	SLC7A4
Domain Architecture
Description	Cationic amino acid transporter 4 (CAT-4) (CAT4).

LAT2_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.106637 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHI5, Q9UKQ6, Q9UKQ7, Q9UKQ8, Q9Y445	Gene names	SLC7A8, LAT2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2).

LAT2_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.107253 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXW9	Gene names	Slc7a8, Lat2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2).

XCT_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.052742 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPY5	Gene names	SLC7A11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT) (Calcium channel blocker resistance protein CCBR1).

XCT_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.058520 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WTR6	Gene names	Slc7a11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT).

YLA1_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.057343 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UM01, O95984, Q9P2V5	Gene names	SLC7A7
Domain Architecture
Description	Y+L amino acid transporter 1 (y(+)L-type amino acid transporter 1) (y+LAT-1) (Y+LAT1) (Monocyte amino acid permease 2) (MOP-2).

Hits sorted by NC score

S12A6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A6_MOUSE
NC score	0.999225 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A4_MOUSE
NC score	0.996957 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JIS8, O55069, Q9ET57	Gene names	Slc12a4, Kcc1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).

S12A4_HUMAN
NC score	0.996905 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UP95, O60632, O75893, Q13953, Q96LD5	Gene names	SLC12A4, KCC1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1).

S12A7_MOUSE
NC score	0.994345 (rank : 5)	θ value	0 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A7_HUMAN
NC score	0.993834 (rank : 6)	θ value	0 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2	Gene names	SLC12A7, KCC4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A5_HUMAN
NC score	0.993246 (rank : 7)	θ value	0 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

S12A5_MOUSE
NC score	0.993142 (rank : 8)	θ value	0 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

S12A3_MOUSE
NC score	0.833241 (rank : 9)	θ value	1.7238e-59 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	P59158	Gene names	Slc12a3, Tsc
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A3_HUMAN
NC score	0.816516 (rank : 10)	θ value	3.974e-56 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	P55017	Gene names	SLC12A3, TSC
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A2_MOUSE
NC score	0.809632 (rank : 11)	θ value	2.84797e-54 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A2_HUMAN
NC score	0.807786 (rank : 12)	θ value	2.18062e-54 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	P55011, Q8N713, Q8WWH7	Gene names	SLC12A2, NKCC1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A1_HUMAN
NC score	0.801784 (rank : 13)	θ value	3.84914e-51 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q13621	Gene names	SLC12A1, NKCC2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter).

S12A1_MOUSE
NC score	0.801674 (rank : 14)	θ value	1.46268e-50 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	P55014, O35938, Q91W55, Q9Z1E0	Gene names	Slc12a1, Nkcc2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (BSC1) (Kidney-specific Na-K-Cl symporter).

CTR2_MOUSE
NC score	0.212208 (rank : 15)	θ value	0.000270298 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P18581	Gene names	Slc7a2, Atrc2, Tea
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (TEA protein) (T-cell early activation protein) (20.5).

CTR2_HUMAN
NC score	0.188325 (rank : 16)	θ value	0.000461057 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P52569	Gene names	SLC7A2, ATRC2
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2).

CTR1_MOUSE
NC score	0.177353 (rank : 17)	θ value	0.0252991 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q09143, P30824	Gene names	Slc7a1, Atrc1, Rec-1
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).

CTR1_HUMAN
NC score	0.162649 (rank : 18)	θ value	0.00509761 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	P30825	Gene names	SLC7A1, ATRC1, REC1L
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor homolog) (ERR) (Ecotropic retrovirus receptor homolog).

CTR3_HUMAN
NC score	0.147021 (rank : 19)	θ value	0.163984 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WY07, Q8N185, Q8NCA7, Q96SZ7	Gene names	SLC7A3, ATRC3, CAT3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

CTR3_MOUSE
NC score	0.142090 (rank : 20)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P70423	Gene names	Slc7a3, Atrc3, Cat3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

BAT1_MOUSE
NC score	0.122116 (rank : 21)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXA6	Gene names	Slc7a9, Bat1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

LAT2_MOUSE
NC score	0.107253 (rank : 22)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXW9	Gene names	Slc7a8, Lat2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2).

LAT2_HUMAN
NC score	0.106637 (rank : 23)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHI5, Q9UKQ6, Q9UKQ7, Q9UKQ8, Q9Y445	Gene names	SLC7A8, LAT2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2).

BAT1_HUMAN
NC score	0.104275 (rank : 24)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P82251	Gene names	SLC7A9, BAT1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

CTR4_HUMAN
NC score	0.102070 (rank : 25)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	O43246, Q3KNQ6, Q4VC45, Q6IBY8, Q96H88	Gene names	SLC7A4
Domain Architecture
Description	Cationic amino acid transporter 4 (CAT-4) (CAT4).

AAA1_MOUSE
NC score	0.087389 (rank : 26)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P63115, Q9CW25, Q9JMH8	Gene names	Slc7a10, Asc1
Domain Architecture	No domain graphic available
Description	Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).

AAA1_HUMAN
NC score	0.080837 (rank : 27)	θ value	0.0431538 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NS82	Gene names	SLC7A10, ASC1
Domain Architecture
Description	Asc-type amino acid transporter 1 (Asc-1).

LAT1_HUMAN
NC score	0.061590 (rank : 28)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q01650, Q9UBN8, Q9UP15, Q9UQC0	Gene names	SLC7A5, CD98LC, LAT1, MPE16
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain) (Integral membrane protein E16) (hLAT1).

XCT_MOUSE
NC score	0.058520 (rank : 29)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	58	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WTR6	Gene names	Slc7a11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT).

LAT1_MOUSE
NC score	0.057773 (rank : 30)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z127, Q9JMI4	Gene names	Slc7a5, Lat1
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC).

YLA1_HUMAN
NC score	0.057343 (rank : 31)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	58	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UM01, O95984, Q9P2V5	Gene names	SLC7A7
Domain Architecture
Description	Y+L amino acid transporter 1 (y(+)L-type amino acid transporter 1) (y+LAT-1) (Y+LAT1) (Monocyte amino acid permease 2) (MOP-2).

XCT_HUMAN
NC score	0.052742 (rank : 32)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	58	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPY5	Gene names	SLC7A11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT) (Calcium channel blocker resistance protein CCBR1).

G137B_HUMAN
NC score	0.049166 (rank : 33)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	7
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

S36A1_HUMAN
NC score	0.033868 (rank : 34)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z2H8, Q7Z7C0, Q96M74	Gene names	SLC36A1, PAT1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

DNMT1_HUMAN
NC score	0.033405 (rank : 35)	θ value	0.0961366 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	401	Shared Neighborhood Hits	9
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DGAT1_HUMAN
NC score	0.026871 (rank : 36)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	O75907, Q96BB8	Gene names	DGAT1, AGRP1, DGAT
Domain Architecture
Description	Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Diglyceride acyltransferase) (ACAT-related gene product 1).

DGAT1_MOUSE
NC score	0.025089 (rank : 37)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2A7, Q9D7Q5	Gene names	Dgat1, Dgat
Domain Architecture
Description	Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Diglyceride acyltransferase).

COX10_MOUSE
NC score	0.024969 (rank : 38)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

RM21_HUMAN
NC score	0.020263 (rank : 39)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2W9	Gene names	MRPL21
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L21, mitochondrial precursor (L21mt) (MRP-L21).

HS90A_MOUSE
NC score	0.018456 (rank : 40)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

SOAT2_HUMAN
NC score	0.018231 (rank : 41)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	O75908, Q96TD4, Q9UNR2	Gene names	SOAT2, ACACT2, ACAT2
Domain Architecture
Description	Sterol O-acyltransferase 2 (EC 2.3.1.26) (Cholesterol acyltransferase 2) (Acyl coenzyme A:cholesterol acyltransferase 2) (ACAT-2).

MAP1B_HUMAN
NC score	0.018165 (rank : 42)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	903	Shared Neighborhood Hits	11
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NASP_HUMAN
NC score	0.016847 (rank : 43)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	709	Shared Neighborhood Hits	10
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

MAP1B_MOUSE
NC score	0.016520 (rank : 44)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	977	Shared Neighborhood Hits	11
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PRP6_HUMAN
NC score	0.016021 (rank : 45)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	O94906, O95109, Q5VXS5, Q9H3Z1, Q9H4T9, Q9H4U8, Q9NTE6	Gene names	PRPF6, C20orf14
Domain Architecture
Description	Pre-mRNA-processing factor 6 homolog (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein).

PRP6_MOUSE
NC score	0.016012 (rank : 46)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YR7, Q8CIK9, Q8R3M8, Q99JN1, Q9CSZ0	Gene names	Prpf6
Domain Architecture
Description	Pre-mRNA-processing factor 6 homolog (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein).

PMS2_MOUSE
NC score	0.014602 (rank : 47)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

HS90B_HUMAN
NC score	0.013577 (rank : 48)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

MYST3_MOUSE
NC score	0.012088 (rank : 49)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	688	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

SNIP_HUMAN
NC score	0.010854 (rank : 50)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	313	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

NPT2B_MOUSE
NC score	0.008410 (rank : 51)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBP0, Q9Z290	Gene names	Slc34a2, Npt2b
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 2B (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2).

GOGA4_HUMAN
NC score	0.008359 (rank : 52)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	2034	Shared Neighborhood Hits	20
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

EDG1_MOUSE
NC score	0.006512 (rank : 53)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	867	Shared Neighborhood Hits	10
SwissProt Accessions	O08530, Q9R235	Gene names	Edg1, Lpb1
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1) (Lysophospholipid receptor B1).

P52K_HUMAN
NC score	0.006162 (rank : 54)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

RHG09_HUMAN
NC score	0.005821 (rank : 55)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	186	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

IF3A_HUMAN
NC score	0.005078 (rank : 56)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	875	Shared Neighborhood Hits	8
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

EDG1_HUMAN
NC score	0.004953 (rank : 57)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	860	Shared Neighborhood Hits	7
SwissProt Accessions	P21453	Gene names	EDG1
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1).

STX12_HUMAN
NC score	0.004432 (rank : 58)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	226	Shared Neighborhood Hits	6
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

PLEC1_HUMAN
NC score	0.004147 (rank : 59)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	1326	Shared Neighborhood Hits	11
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

KIF4A_MOUSE
NC score	0.002705 (rank : 60)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	1033	Shared Neighborhood Hits	9
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KCC2B_MOUSE
NC score	0.001116 (rank : 61)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	841	Shared Neighborhood Hits	4
SwissProt Accessions	P28652, Q5SVH9	Gene names	Camk2b, Camk2d
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

OR5T1_HUMAN
NC score	0.000653 (rank : 62)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	654	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NG75	Gene names	OR5T1
Domain Architecture	No domain graphic available
Description	Olfactory receptor 5T1 (Olfactory receptor OR11-179).

TAOK3_MOUSE
NC score	0.000247 (rank : 63)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	1458	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

OR7A2_HUMAN
NC score	-0.001616 (rank : 64)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	782	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NGA2, Q96R95	Gene names	OR7A2, OR7A7
Domain Architecture
Description	Olfactory receptor 7A2.