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Network neighborhood for query Sequence : G137B_HUMAN

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G137B_HUMAN
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

G137B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

P3_MOUSE
θ value	0.0563607 (rank : 2)	NC score	0.137897 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P21129, Q8QZR2	Gene names	Slc10a3, P3
Domain Architecture	No domain graphic available
Description	P3 protein (Solute carrier family 10 member 3).

O52N5_HUMAN
θ value	0.0736092 (rank : 3)	NC score	0.014600 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	631	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NH56	Gene names	OR52N5
Domain Architecture
Description	Olfactory receptor 52N5.

NU5M_MOUSE
θ value	0.163984 (rank : 4)	NC score	0.089836 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P03921	Gene names	Mtnd5, mt-Nd5, Nd5
Domain Architecture
Description	NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3) (NADH dehydrogenase subunit 5).

CCRL2_HUMAN
θ value	0.21417 (rank : 5)	NC score	0.029291 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	415	Shared Neighborhood Hits	4
SwissProt Accessions	O00421, O75307, Q4VBB0, Q6IPX0, Q96KP5, Q9UPG0	Gene names	CCRL2, CCR11, CCR6, CKRX, CRAM, HCR
Domain Architecture	No domain graphic available
Description	C-C chemokine receptor-like 2 (Putative MCP-1 chemokine receptor) (Chemokine receptor CCR11) (Chemokine receptor X).

P3_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.126281 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P09131	Gene names	SLC10A3, DXS253E, P3
Domain Architecture
Description	P3 protein (Solute carrier family 10 member 3).

XCR1_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.017653 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	711	Shared Neighborhood Hits	5
SwissProt Accessions	P46094	Gene names	XCR1, CCXCR1, GPR5
Domain Architecture
Description	Chemokine XC receptor 1 (XC chemokine receptor 1) (Lymphotactin receptor) (G-protein coupled receptor 5).

MUC2_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.027265 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	906	Shared Neighborhood Hits	5
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

S12A7_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.057629 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2	Gene names	SLC12A7, KCC4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

RAPH1_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.036668 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	593	Shared Neighborhood Hits	8
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PI5PA_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.046365 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	749	Shared Neighborhood Hits	11
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

HCN2_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.018789 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	369	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

O52N2_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.010035 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	668	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NGI0	Gene names	OR52N2
Domain Architecture
Description	Olfactory receptor 52N2.

PI5PA_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.044876 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	331	Shared Neighborhood Hits	7
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SFPQ_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.022827 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	986	Shared Neighborhood Hits	9
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

ALG6_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.049591 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y672, Q9H3I0	Gene names	ALG6
Domain Architecture
Description	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.-) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase).

MMP16_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.019919 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

SOS2_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.024203 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

TAF4_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.035649 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	687	Shared Neighborhood Hits	8
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TERF2_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.039269 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

GDPD4_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.027384 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TT99, Q8BI25	Gene names	Gdpd4, Gde6
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase domain-containing protein 4 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 6).

GP141_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.021631 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQP0, Q80UC5	Gene names	Gpr141, Pgr13
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13).

MMP16_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.019158 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

NCOR2_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.023950 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	790	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PDLI7_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.016827 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	547	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PRELP_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.010732 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

RPC8_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.061978 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y535, Q96AE3, Q9BY95	Gene names	POLR3H, KIAA1665
Domain Architecture
Description	DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide (EC 2.7.7.6) (RPC8).

RPC8_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.062296 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2C6, Q91XE5	Gene names	Polr3h
Domain Architecture
Description	DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide (EC 2.7.7.6) (RPC8).

SIN3B_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.025761 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

ADCY6_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.012856 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O43306, Q9NR75	Gene names	ADCY6, KIAA0422
Domain Architecture
Description	Adenylate cyclase type 6 (EC 4.6.1.1) (Adenylate cyclase type VI) (ATP pyrophosphate-lyase 6) (Ca(2+)-inhibitable adenylyl cyclase).

EPOR_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.028788 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

H2B2C_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.021507 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q6DN03	Gene names	HIST2H2BC
Domain Architecture	No domain graphic available
Description	Histone H2B type 2-C (H2.t) (H2B/t).

H2B2D_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.020819 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q6DRA6	Gene names	HIST2H2BD
Domain Architecture	No domain graphic available
Description	Histone H2B type 2-D.

S12A5_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.051648 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

S12A5_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.051666 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

SC5A4_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.016810 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ET37	Gene names	Slc5a4a
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

S35C2_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.029554 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCX2	Gene names	Slc35c2, Ovcov1
Domain Architecture	No domain graphic available
Description	Solute carrier family 35 member C2 (Ovarian cancer overexpressed gene 1 protein).

SGIP1_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.025009 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

WBP11_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.035034 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	354	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.034795 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	362	Shared Neighborhood Hits	6
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

DDR1_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.001869 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	818	Shared Neighborhood Hits	2
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DYN2_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.010663 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

S12A6_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.049166 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A6_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.049277 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A7_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.049825 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

STRC_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.019306 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

Hits sorted by NC score

G137B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

P3_MOUSE
NC score	0.137897 (rank : 2)	θ value	0.0563607 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P21129, Q8QZR2	Gene names	Slc10a3, P3
Domain Architecture	No domain graphic available
Description	P3 protein (Solute carrier family 10 member 3).

P3_HUMAN
NC score	0.126281 (rank : 3)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P09131	Gene names	SLC10A3, DXS253E, P3
Domain Architecture
Description	P3 protein (Solute carrier family 10 member 3).

NU5M_MOUSE
NC score	0.089836 (rank : 4)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P03921	Gene names	Mtnd5, mt-Nd5, Nd5
Domain Architecture
Description	NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3) (NADH dehydrogenase subunit 5).

RPC8_MOUSE
NC score	0.062296 (rank : 5)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2C6, Q91XE5	Gene names	Polr3h
Domain Architecture
Description	DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide (EC 2.7.7.6) (RPC8).

RPC8_HUMAN
NC score	0.061978 (rank : 6)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y535, Q96AE3, Q9BY95	Gene names	POLR3H, KIAA1665
Domain Architecture
Description	DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide (EC 2.7.7.6) (RPC8).

S12A7_HUMAN
NC score	0.057629 (rank : 7)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2	Gene names	SLC12A7, KCC4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A5_MOUSE
NC score	0.051666 (rank : 8)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

S12A5_HUMAN
NC score	0.051648 (rank : 9)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

S12A7_MOUSE
NC score	0.049825 (rank : 10)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

ALG6_HUMAN
NC score	0.049591 (rank : 11)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y672, Q9H3I0	Gene names	ALG6
Domain Architecture
Description	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.-) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase).

S12A6_MOUSE
NC score	0.049277 (rank : 12)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A6_HUMAN
NC score	0.049166 (rank : 13)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

PI5PA_HUMAN
NC score	0.046365 (rank : 14)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	749	Shared Neighborhood Hits	11
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PI5PA_MOUSE
NC score	0.044876 (rank : 15)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	331	Shared Neighborhood Hits	7
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

TERF2_HUMAN
NC score	0.039269 (rank : 16)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

RAPH1_HUMAN
NC score	0.036668 (rank : 17)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	593	Shared Neighborhood Hits	8
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

TAF4_HUMAN
NC score	0.035649 (rank : 18)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	687	Shared Neighborhood Hits	8
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

WBP11_HUMAN
NC score	0.035034 (rank : 19)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	354	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
NC score	0.034795 (rank : 20)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	362	Shared Neighborhood Hits	6
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

S35C2_MOUSE
NC score	0.029554 (rank : 21)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCX2	Gene names	Slc35c2, Ovcov1
Domain Architecture	No domain graphic available
Description	Solute carrier family 35 member C2 (Ovarian cancer overexpressed gene 1 protein).

CCRL2_HUMAN
NC score	0.029291 (rank : 22)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	415	Shared Neighborhood Hits	4
SwissProt Accessions	O00421, O75307, Q4VBB0, Q6IPX0, Q96KP5, Q9UPG0	Gene names	CCRL2, CCR11, CCR6, CKRX, CRAM, HCR
Domain Architecture	No domain graphic available
Description	C-C chemokine receptor-like 2 (Putative MCP-1 chemokine receptor) (Chemokine receptor CCR11) (Chemokine receptor X).

EPOR_MOUSE
NC score	0.028788 (rank : 23)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

GDPD4_MOUSE
NC score	0.027384 (rank : 24)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TT99, Q8BI25	Gene names	Gdpd4, Gde6
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase domain-containing protein 4 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 6).

MUC2_HUMAN
NC score	0.027265 (rank : 25)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	906	Shared Neighborhood Hits	5
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SIN3B_HUMAN
NC score	0.025761 (rank : 26)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

SGIP1_MOUSE
NC score	0.025009 (rank : 27)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SOS2_HUMAN
NC score	0.024203 (rank : 28)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

NCOR2_MOUSE
NC score	0.023950 (rank : 29)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	790	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

SFPQ_HUMAN
NC score	0.022827 (rank : 30)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	986	Shared Neighborhood Hits	9
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

GP141_MOUSE
NC score	0.021631 (rank : 31)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQP0, Q80UC5	Gene names	Gpr141, Pgr13
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13).

H2B2C_HUMAN
NC score	0.021507 (rank : 32)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q6DN03	Gene names	HIST2H2BC
Domain Architecture	No domain graphic available
Description	Histone H2B type 2-C (H2.t) (H2B/t).

H2B2D_HUMAN
NC score	0.020819 (rank : 33)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q6DRA6	Gene names	HIST2H2BD
Domain Architecture	No domain graphic available
Description	Histone H2B type 2-D.

MMP16_HUMAN
NC score	0.019919 (rank : 34)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

STRC_MOUSE
NC score	0.019306 (rank : 35)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

MMP16_MOUSE
NC score	0.019158 (rank : 36)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

HCN2_HUMAN
NC score	0.018789 (rank : 37)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	369	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

XCR1_HUMAN
NC score	0.017653 (rank : 38)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	711	Shared Neighborhood Hits	5
SwissProt Accessions	P46094	Gene names	XCR1, CCXCR1, GPR5
Domain Architecture
Description	Chemokine XC receptor 1 (XC chemokine receptor 1) (Lymphotactin receptor) (G-protein coupled receptor 5).

PDLI7_HUMAN
NC score	0.016827 (rank : 39)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	547	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SC5A4_MOUSE
NC score	0.016810 (rank : 40)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ET37	Gene names	Slc5a4a
Domain Architecture
Description	Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3).

O52N5_HUMAN
NC score	0.014600 (rank : 41)	θ value	0.0736092 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	631	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NH56	Gene names	OR52N5
Domain Architecture
Description	Olfactory receptor 52N5.

ADCY6_HUMAN
NC score	0.012856 (rank : 42)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O43306, Q9NR75	Gene names	ADCY6, KIAA0422
Domain Architecture
Description	Adenylate cyclase type 6 (EC 4.6.1.1) (Adenylate cyclase type VI) (ATP pyrophosphate-lyase 6) (Ca(2+)-inhibitable adenylyl cyclase).

PRELP_HUMAN
NC score	0.010732 (rank : 43)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

DYN2_MOUSE
NC score	0.010663 (rank : 44)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

O52N2_HUMAN
NC score	0.010035 (rank : 45)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	668	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NGI0	Gene names	OR52N2
Domain Architecture
Description	Olfactory receptor 52N2.

DDR1_MOUSE
NC score	0.001869 (rank : 46)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	818	Shared Neighborhood Hits	2
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).