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Network neighborhood for query Sequence : S12A7_HUMAN

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S12A7_HUMAN
 
SwissProt Accessions Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2 Gene names SLC12A7, KCC4
Domain
Architecture
Description Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).
Rank Plots


Hits sorted by θ


S12A4_HUMAN
 
θ value 0 (rank : 1) NC score 0.994931 (rank : 6)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 22
SwissProt Accessions Q9UP95, O60632, O75893, Q13953, Q96LD5 Gene names SLC12A4, KCC1
Domain
Architecture
Description Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1).
S12A4_MOUSE
 
θ value 0 (rank : 2) NC score 0.995149 (rank : 5)
Query Neighborhood Hits 46 Target Neighborhood Hits 28 Shared Neighborhood Hits 22
SwissProt Accessions Q9JIS8, O55069, Q9ET57 Gene names Slc12a4, Kcc1
Domain
Architecture
Description Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).
S12A5_HUMAN
 
θ value 0 (rank : 3) NC score 0.996581 (rank : 3)
Query Neighborhood Hits 46 Target Neighborhood Hits 68 Shared Neighborhood Hits 28
SwissProt Accessions Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4 Gene names SLC12A5, KCC2, KIAA1176
Domain
Architecture
Description Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).
S12A5_MOUSE
 
θ value 0 (rank : 4) NC score 0.996568 (rank : 4)
Query Neighborhood Hits 46 Target Neighborhood Hits 59 Shared Neighborhood Hits 28
SwissProt Accessions Q91V14, Q9Z0M7 Gene names Slc12a5, Kcc2
Domain
Architecture
Description Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).
S12A6_HUMAN
 
θ value 0 (rank : 5) NC score 0.993834 (rank : 7)
Query Neighborhood Hits 46 Target Neighborhood Hits 58 Shared Neighborhood Hits 27
SwissProt Accessions Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665 Gene names SLC12A6, KCC3
Domain
Architecture
Description Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).
S12A6_MOUSE
 
θ value 0 (rank : 6) NC score 0.993650 (rank : 8)
Query Neighborhood Hits 46 Target Neighborhood Hits 67 Shared Neighborhood Hits 27
SwissProt Accessions Q924N4, Q924N3 Gene names Slc12a6, Kcc3
Domain
Architecture
Description Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).
S12A7_HUMAN
 
θ value 0 (rank : 7) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 46 Target Neighborhood Hits 46 Shared Neighborhood Hits 46
SwissProt Accessions Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2 Gene names SLC12A7, KCC4
Domain
Architecture
Description Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).
S12A7_MOUSE
 
θ value 0 (rank : 8) NC score 0.998290 (rank : 2)
Query Neighborhood Hits 46 Target Neighborhood Hits 56 Shared Neighborhood Hits 34
SwissProt Accessions Q9WVL3 Gene names Slc12a7, Kcc4
Domain
Architecture
Description Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).
S12A3_MOUSE
 
θ value 4.81303e-86 (rank : 9) NC score 0.845295 (rank : 9)
Query Neighborhood Hits 46 Target Neighborhood Hits 23 Shared Neighborhood Hits 16
SwissProt Accessions P59158 Gene names Slc12a3, Tsc
Domain
Architecture
Description Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).
S12A2_HUMAN
 
θ value 2.10721e-57 (rank : 10) NC score 0.818451 (rank : 12)
Query Neighborhood Hits 46 Target Neighborhood Hits 56 Shared Neighborhood Hits 21
SwissProt Accessions P55011, Q8N713, Q8WWH7 Gene names SLC12A2, NKCC1
Domain
Architecture
Description Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).
S12A3_HUMAN
 
θ value 2.10721e-57 (rank : 11) NC score 0.827663 (rank : 10)
Query Neighborhood Hits 46 Target Neighborhood Hits 27 Shared Neighborhood Hits 16
SwissProt Accessions P55017 Gene names SLC12A3, TSC
Domain
Architecture
Description Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).
S12A2_MOUSE
 
θ value 3.59435e-57 (rank : 12) NC score 0.818899 (rank : 11)
Query Neighborhood Hits 46 Target Neighborhood Hits 55 Shared Neighborhood Hits 20
SwissProt Accessions P55012 Gene names Slc12a2, Nkcc1
Domain
Architecture
Description Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).
S12A1_HUMAN
 
θ value 1.41344e-53 (rank : 13) NC score 0.810717 (rank : 13)
Query Neighborhood Hits 46 Target Neighborhood Hits 28 Shared Neighborhood Hits 19
SwissProt Accessions Q13621 Gene names SLC12A1, NKCC2
Domain
Architecture
Description Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter).
S12A1_MOUSE
 
θ value 9.16162e-53 (rank : 14) NC score 0.810413 (rank : 14)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 19
SwissProt Accessions P55014, O35938, Q91W55, Q9Z1E0 Gene names Slc12a1, Nkcc2
Domain
Architecture
Description Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (BSC1) (Kidney-specific Na-K-Cl symporter).
LAT2_HUMAN
 
θ value 0.000158464 (rank : 15) NC score 0.119676 (rank : 22)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 20
SwissProt Accessions Q9UHI5, Q9UKQ6, Q9UKQ7, Q9UKQ8, Q9Y445 Gene names SLC7A8, LAT2
Domain
Architecture
Description Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2).
LAT2_MOUSE
 
θ value 0.00020696 (rank : 16) NC score 0.119262 (rank : 23)
Query Neighborhood Hits 46 Target Neighborhood Hits 30 Shared Neighborhood Hits 20
SwissProt Accessions Q9QXW9 Gene names Slc7a8, Lat2
Domain
Architecture
Description Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2).
CTR2_MOUSE
 
θ value 0.0113563 (rank : 17) NC score 0.201179 (rank : 15)
Query Neighborhood Hits 46 Target Neighborhood Hits 37 Shared Neighborhood Hits 26
SwissProt Accessions P18581 Gene names Slc7a2, Atrc2, Tea
Domain
Architecture
Description Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (TEA protein) (T-cell early activation protein) (20.5).
CTR4_HUMAN
 
θ value 0.0736092 (rank : 18) NC score 0.095140 (rank : 25)
Query Neighborhood Hits 46 Target Neighborhood Hits 27 Shared Neighborhood Hits 18
SwissProt Accessions O43246, Q3KNQ6, Q4VC45, Q6IBY8, Q96H88 Gene names SLC7A4
Domain
Architecture
Description Cationic amino acid transporter 4 (CAT-4) (CAT4).
SETX_HUMAN
 
θ value 0.125558 (rank : 19) NC score 0.025824 (rank : 34)
Query Neighborhood Hits 46 Target Neighborhood Hits 368 Shared Neighborhood Hits 3
SwissProt Accessions Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9 Gene names SETX, ALS4, KIAA0625, SCAR1
Domain
Architecture
Description Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).
CTR3_HUMAN
 
θ value 0.163984 (rank : 20) NC score 0.136341 (rank : 19)
Query Neighborhood Hits 46 Target Neighborhood Hits 35 Shared Neighborhood Hits 22
SwissProt Accessions Q8WY07, Q8N185, Q8NCA7, Q96SZ7 Gene names SLC7A3, ATRC3, CAT3
Domain
Architecture
Description Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).
AAA1_HUMAN
 
θ value 0.21417 (rank : 21) NC score 0.088261 (rank : 27)
Query Neighborhood Hits 46 Target Neighborhood Hits 25 Shared Neighborhood Hits 19
SwissProt Accessions Q9NS82 Gene names SLC7A10, ASC1
Domain
Architecture
Description Asc-type amino acid transporter 1 (Asc-1).
BAT1_MOUSE
 
θ value 0.279714 (rank : 22) NC score 0.125228 (rank : 21)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 22
SwissProt Accessions Q9QXA6 Gene names Slc7a9, Bat1
Domain
Architecture
Description B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).
CTR1_MOUSE
 
θ value 0.279714 (rank : 23) NC score 0.166803 (rank : 17)
Query Neighborhood Hits 46 Target Neighborhood Hits 36 Shared Neighborhood Hits 28
SwissProt Accessions Q09143, P30824 Gene names Slc7a1, Atrc1, Rec-1
Domain
Architecture
Description High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).
CTR1_HUMAN
 
θ value 0.365318 (rank : 24) NC score 0.149927 (rank : 18)
Query Neighborhood Hits 46 Target Neighborhood Hits 41 Shared Neighborhood Hits 27
SwissProt Accessions P30825 Gene names SLC7A1, ATRC1, REC1L
Domain
Architecture
Description High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor homolog) (ERR) (Ecotropic retrovirus receptor homolog).
CTR2_HUMAN
 
θ value 0.47712 (rank : 25) NC score 0.176902 (rank : 16)
Query Neighborhood Hits 46 Target Neighborhood Hits 38 Shared Neighborhood Hits 27
SwissProt Accessions P52569 Gene names SLC7A2, ATRC2
Domain
Architecture
Description Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2).
G137B_HUMAN
 
θ value 1.06291 (rank : 26) NC score 0.057629 (rank : 33)
Query Neighborhood Hits 46 Target Neighborhood Hits 46 Shared Neighborhood Hits 8
SwissProt Accessions O60478 Gene names GPR137B, TM7SF1
Domain
Architecture

No domain graphic available

Description Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).
CTR3_MOUSE
 
θ value 1.38821 (rank : 27) NC score 0.131177 (rank : 20)
Query Neighborhood Hits 46 Target Neighborhood Hits 36 Shared Neighborhood Hits 24
SwissProt Accessions P70423 Gene names Slc7a3, Atrc3, Cat3
Domain
Architecture
Description Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).
GPR84_HUMAN
 
θ value 1.38821 (rank : 28) NC score 0.011048 (rank : 39)
Query Neighborhood Hits 46 Target Neighborhood Hits 682 Shared Neighborhood Hits 7
SwissProt Accessions Q9NQS5 Gene names GPR84, EX33
Domain
Architecture

No domain graphic available

Description Probable G-protein coupled receptor 84 (Inflammation-related G-protein coupled receptor EX33).
BAT1_HUMAN
 
θ value 2.36792 (rank : 29) NC score 0.107226 (rank : 24)
Query Neighborhood Hits 46 Target Neighborhood Hits 31 Shared Neighborhood Hits 22
SwissProt Accessions P82251 Gene names SLC7A9, BAT1
Domain
Architecture
Description B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).
CCD11_MOUSE
 
θ value 3.0926 (rank : 30) NC score 0.004689 (rank : 44)
Query Neighborhood Hits 46 Target Neighborhood Hits 498 Shared Neighborhood Hits 4
SwissProt Accessions Q9D439 Gene names Ccdc11
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 11.
PLCB4_HUMAN
 
θ value 3.0926 (rank : 31) NC score 0.003786 (rank : 46)
Query Neighborhood Hits 46 Target Neighborhood Hits 658 Shared Neighborhood Hits 4
SwissProt Accessions Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2 Gene names PLCB4
Domain
Architecture
Description 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).
EDG1_HUMAN
 
θ value 4.03905 (rank : 32) NC score 0.003312 (rank : 48)
Query Neighborhood Hits 46 Target Neighborhood Hits 860 Shared Neighborhood Hits 5
SwissProt Accessions P21453 Gene names EDG1
Domain
Architecture
Description Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1).
GPR84_MOUSE
 
θ value 4.03905 (rank : 33) NC score 0.003592 (rank : 47)
Query Neighborhood Hits 46 Target Neighborhood Hits 703 Shared Neighborhood Hits 3
SwissProt Accessions Q8CIM5, Q99MX9 Gene names Gpr84
Domain
Architecture

No domain graphic available

Description Probable G-protein coupled receptor 84.
LAT1_HUMAN
 
θ value 4.03905 (rank : 34) NC score 0.066592 (rank : 28)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 18
SwissProt Accessions Q01650, Q9UBN8, Q9UP15, Q9UQC0 Gene names SLC7A5, CD98LC, LAT1, MPE16
Domain
Architecture
Description Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain) (Integral membrane protein E16) (hLAT1).
MDN1_HUMAN
 
θ value 4.03905 (rank : 35) NC score 0.018275 (rank : 35)
Query Neighborhood Hits 46 Target Neighborhood Hits 662 Shared Neighborhood Hits 5
SwissProt Accessions Q9NU22, O15019 Gene names MDN1, KIAA0301
Domain
Architecture
Description Midasin (MIDAS-containing protein).
NBEA_HUMAN
 
θ value 4.03905 (rank : 36) NC score 0.011643 (rank : 37)
Query Neighborhood Hits 46 Target Neighborhood Hits 186 Shared Neighborhood Hits 4
SwissProt Accessions Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1 Gene names NBEA, BCL8B, KIAA1544, LYST2
Domain
Architecture
Description Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).
NBEA_MOUSE
 
θ value 4.03905 (rank : 37) NC score 0.011537 (rank : 38)
Query Neighborhood Hits 46 Target Neighborhood Hits 225 Shared Neighborhood Hits 4
SwissProt Accessions Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9 Gene names Nbea, Lyst2
Domain
Architecture
Description Protein neurobeachin (Lysosomal-trafficking regulator 2).
ADCY6_HUMAN
 
θ value 5.27518 (rank : 38) NC score 0.004712 (rank : 43)
Query Neighborhood Hits 46 Target Neighborhood Hits 52 Shared Neighborhood Hits 4
SwissProt Accessions O43306, Q9NR75 Gene names ADCY6, KIAA0422
Domain
Architecture
Description Adenylate cyclase type 6 (EC 4.6.1.1) (Adenylate cyclase type VI) (ATP pyrophosphate-lyase 6) (Ca(2+)-inhibitable adenylyl cyclase).
AFF2_HUMAN
 
θ value 6.88961 (rank : 39) NC score 0.005079 (rank : 42)
Query Neighborhood Hits 46 Target Neighborhood Hits 218 Shared Neighborhood Hits 2
SwissProt Accessions P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5 Gene names AFF2, FMR2, OX19
Domain
Architecture
Description AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).
CCD19_HUMAN
 
θ value 6.88961 (rank : 40) NC score 0.002035 (rank : 49)
Query Neighborhood Hits 46 Target Neighborhood Hits 639 Shared Neighborhood Hits 4
SwissProt Accessions Q9UL16 Gene names CCDC19, NESG1
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).
LAT1_MOUSE
 
θ value 6.88961 (rank : 41) NC score 0.062943 (rank : 31)
Query Neighborhood Hits 46 Target Neighborhood Hits 26 Shared Neighborhood Hits 18
SwissProt Accessions Q9Z127, Q9JMI4 Gene names Slc7a5, Lat1
Domain
Architecture
Description Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC).
ADCY6_MOUSE
 
θ value 8.99809 (rank : 42) NC score 0.004024 (rank : 45)
Query Neighborhood Hits 46 Target Neighborhood Hits 57 Shared Neighborhood Hits 3
SwissProt Accessions Q01341 Gene names Adcy6
Domain
Architecture
Description Adenylate cyclase type 6 (EC 4.6.1.1) (Adenylate cyclase type VI) (ATP pyrophosphate-lyase 6) (Ca(2+)-inhibitable adenylyl cyclase).
CC045_HUMAN
 
θ value 8.99809 (rank : 43) NC score 0.013298 (rank : 36)
Query Neighborhood Hits 46 Target Neighborhood Hits 3 Shared Neighborhood Hits 2
SwissProt Accessions Q8N112 Gene names C3orf45
Domain
Architecture

No domain graphic available

Description Uncharacterized protein C3orf45.
GCS1_HUMAN
 
θ value 8.99809 (rank : 44) NC score 0.006442 (rank : 41)
Query Neighborhood Hits 46 Target Neighborhood Hits 6 Shared Neighborhood Hits 2
SwissProt Accessions Q13724, Q17RN9, Q8TCT5 Gene names GCS1
Domain
Architecture
Description Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A- glucosidase I).
GGH_MOUSE
 
θ value 8.99809 (rank : 45) NC score 0.007795 (rank : 40)
Query Neighborhood Hits 46 Target Neighborhood Hits 4 Shared Neighborhood Hits 2
SwissProt Accessions Q9Z0L8, Q9Z0L7 Gene names Ggh
Domain
Architecture
Description Gamma-glutamyl hydrolase precursor (EC 3.4.19.9) (Gamma-Glu-x carboxypeptidase) (Conjugase) (GH) (Folylpolyglutamate hydrolase) (FGPH).
ZN510_HUMAN
 
θ value 8.99809 (rank : 46) NC score -0.003098 (rank : 50)
Query Neighborhood Hits 46 Target Neighborhood Hits 764 Shared Neighborhood Hits 2
SwissProt Accessions Q9Y2H8 Gene names ZNF510, KIAA0972
Domain
Architecture
Description Zinc finger protein 510.
AAA1_MOUSE
 
θ value θ > 10 (rank : 47) NC score 0.094337 (rank : 26)
Query Neighborhood Hits 46 Target Neighborhood Hits 31 Shared Neighborhood Hits 23
SwissProt Accessions P63115, Q9CW25, Q9JMH8 Gene names Slc7a10, Asc1
Domain
Architecture

No domain graphic available

Description Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).
XCT_HUMAN
 
θ value θ > 10 (rank : 48) NC score 0.058328 (rank : 32)
Query Neighborhood Hits 46 Target Neighborhood Hits 26 Shared Neighborhood Hits 17
SwissProt Accessions Q9UPY5 Gene names SLC7A11
Domain
Architecture
Description Cystine/glutamate transporter (Amino acid transport system xc-) (xCT) (Calcium channel blocker resistance protein CCBR1).
XCT_MOUSE
 
θ value θ > 10 (rank : 49) NC score 0.064777 (rank : 29)
Query Neighborhood Hits 46 Target Neighborhood Hits 23 Shared Neighborhood Hits 18
SwissProt Accessions Q9WTR6 Gene names Slc7a11
Domain
Architecture
Description Cystine/glutamate transporter (Amino acid transport system xc-) (xCT).
YLA1_HUMAN
 
θ value θ > 10 (rank : 50) NC score 0.064153 (rank : 30)
Query Neighborhood Hits 46 Target Neighborhood Hits 27 Shared Neighborhood Hits 17
SwissProt Accessions Q9UM01, O95984, Q9P2V5 Gene names SLC7A7
Domain
Architecture
Description Y+L amino acid transporter 1 (y(+)L-type amino acid transporter 1) (y+LAT-1) (Y+LAT1) (Monocyte amino acid permease 2) (MOP-2).

Hits sorted by NC score


S12A7_HUMAN
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 7)
Query Neighborhood Hits 46 Target Neighborhood Hits 46 Shared Neighborhood Hits 46
SwissProt Accessions Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2 Gene names SLC12A7, KCC4
Domain
Architecture
Description Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).
S12A7_MOUSE
 
NC score 0.998290 (rank : 2) θ value 0 (rank : 8)
Query Neighborhood Hits 46 Target Neighborhood Hits 56 Shared Neighborhood Hits 34
SwissProt Accessions Q9WVL3 Gene names Slc12a7, Kcc4
Domain
Architecture
Description Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).
S12A5_HUMAN
 
NC score 0.996581 (rank : 3) θ value 0 (rank : 3)
Query Neighborhood Hits 46 Target Neighborhood Hits 68 Shared Neighborhood Hits 28
SwissProt Accessions Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4 Gene names SLC12A5, KCC2, KIAA1176
Domain
Architecture
Description Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).
S12A5_MOUSE
 
NC score 0.996568 (rank : 4) θ value 0 (rank : 4)
Query Neighborhood Hits 46 Target Neighborhood Hits 59 Shared Neighborhood Hits 28
SwissProt Accessions Q91V14, Q9Z0M7 Gene names Slc12a5, Kcc2
Domain
Architecture
Description Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).
S12A4_MOUSE
 
NC score 0.995149 (rank : 5) θ value 0 (rank : 2)
Query Neighborhood Hits 46 Target Neighborhood Hits 28 Shared Neighborhood Hits 22
SwissProt Accessions Q9JIS8, O55069, Q9ET57 Gene names Slc12a4, Kcc1
Domain
Architecture
Description Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).
S12A4_HUMAN
 
NC score 0.994931 (rank : 6) θ value 0 (rank : 1)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 22
SwissProt Accessions Q9UP95, O60632, O75893, Q13953, Q96LD5 Gene names SLC12A4, KCC1
Domain
Architecture
Description Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1).
S12A6_HUMAN
 
NC score 0.993834 (rank : 7) θ value 0 (rank : 5)
Query Neighborhood Hits 46 Target Neighborhood Hits 58 Shared Neighborhood Hits 27
SwissProt Accessions Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665 Gene names SLC12A6, KCC3
Domain
Architecture
Description Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).
S12A6_MOUSE
 
NC score 0.993650 (rank : 8) θ value 0 (rank : 6)
Query Neighborhood Hits 46 Target Neighborhood Hits 67 Shared Neighborhood Hits 27
SwissProt Accessions Q924N4, Q924N3 Gene names Slc12a6, Kcc3
Domain
Architecture
Description Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).
S12A3_MOUSE
 
NC score 0.845295 (rank : 9) θ value 4.81303e-86 (rank : 9)
Query Neighborhood Hits 46 Target Neighborhood Hits 23 Shared Neighborhood Hits 16
SwissProt Accessions P59158 Gene names Slc12a3, Tsc
Domain
Architecture
Description Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).
S12A3_HUMAN
 
NC score 0.827663 (rank : 10) θ value 2.10721e-57 (rank : 11)
Query Neighborhood Hits 46 Target Neighborhood Hits 27 Shared Neighborhood Hits 16
SwissProt Accessions P55017 Gene names SLC12A3, TSC
Domain
Architecture
Description Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).
S12A2_MOUSE
 
NC score 0.818899 (rank : 11) θ value 3.59435e-57 (rank : 12)
Query Neighborhood Hits 46 Target Neighborhood Hits 55 Shared Neighborhood Hits 20
SwissProt Accessions P55012 Gene names Slc12a2, Nkcc1
Domain
Architecture
Description Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).
S12A2_HUMAN
 
NC score 0.818451 (rank : 12) θ value 2.10721e-57 (rank : 10)
Query Neighborhood Hits 46 Target Neighborhood Hits 56 Shared Neighborhood Hits 21
SwissProt Accessions P55011, Q8N713, Q8WWH7 Gene names SLC12A2, NKCC1
Domain
Architecture
Description Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).
S12A1_HUMAN
 
NC score 0.810717 (rank : 13) θ value 1.41344e-53 (rank : 13)
Query Neighborhood Hits 46 Target Neighborhood Hits 28 Shared Neighborhood Hits 19
SwissProt Accessions Q13621 Gene names SLC12A1, NKCC2
Domain
Architecture
Description Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter).
S12A1_MOUSE
 
NC score 0.810413 (rank : 14) θ value 9.16162e-53 (rank : 14)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 19
SwissProt Accessions P55014, O35938, Q91W55, Q9Z1E0 Gene names Slc12a1, Nkcc2
Domain
Architecture
Description Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (BSC1) (Kidney-specific Na-K-Cl symporter).
CTR2_MOUSE
 
NC score 0.201179 (rank : 15) θ value 0.0113563 (rank : 17)
Query Neighborhood Hits 46 Target Neighborhood Hits 37 Shared Neighborhood Hits 26
SwissProt Accessions P18581 Gene names Slc7a2, Atrc2, Tea
Domain
Architecture
Description Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (TEA protein) (T-cell early activation protein) (20.5).
CTR2_HUMAN
 
NC score 0.176902 (rank : 16) θ value 0.47712 (rank : 25)
Query Neighborhood Hits 46 Target Neighborhood Hits 38 Shared Neighborhood Hits 27
SwissProt Accessions P52569 Gene names SLC7A2, ATRC2
Domain
Architecture
Description Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2).
CTR1_MOUSE
 
NC score 0.166803 (rank : 17) θ value 0.279714 (rank : 23)
Query Neighborhood Hits 46 Target Neighborhood Hits 36 Shared Neighborhood Hits 28
SwissProt Accessions Q09143, P30824 Gene names Slc7a1, Atrc1, Rec-1
Domain
Architecture
Description High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).
CTR1_HUMAN
 
NC score 0.149927 (rank : 18) θ value 0.365318 (rank : 24)
Query Neighborhood Hits 46 Target Neighborhood Hits 41 Shared Neighborhood Hits 27
SwissProt Accessions P30825 Gene names SLC7A1, ATRC1, REC1L
Domain
Architecture
Description High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor homolog) (ERR) (Ecotropic retrovirus receptor homolog).
CTR3_HUMAN
 
NC score 0.136341 (rank : 19) θ value 0.163984 (rank : 20)
Query Neighborhood Hits 46 Target Neighborhood Hits 35 Shared Neighborhood Hits 22
SwissProt Accessions Q8WY07, Q8N185, Q8NCA7, Q96SZ7 Gene names SLC7A3, ATRC3, CAT3
Domain
Architecture
Description Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).
CTR3_MOUSE
 
NC score 0.131177 (rank : 20) θ value 1.38821 (rank : 27)
Query Neighborhood Hits 46 Target Neighborhood Hits 36 Shared Neighborhood Hits 24
SwissProt Accessions P70423 Gene names Slc7a3, Atrc3, Cat3
Domain
Architecture
Description Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).
BAT1_MOUSE
 
NC score 0.125228 (rank : 21) θ value 0.279714 (rank : 22)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 22
SwissProt Accessions Q9QXA6 Gene names Slc7a9, Bat1
Domain
Architecture
Description B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).
LAT2_HUMAN
 
NC score 0.119676 (rank : 22) θ value 0.000158464 (rank : 15)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 20
SwissProt Accessions Q9UHI5, Q9UKQ6, Q9UKQ7, Q9UKQ8, Q9Y445 Gene names SLC7A8, LAT2
Domain
Architecture
Description Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2).
LAT2_MOUSE
 
NC score 0.119262 (rank : 23) θ value 0.00020696 (rank : 16)
Query Neighborhood Hits 46 Target Neighborhood Hits 30 Shared Neighborhood Hits 20
SwissProt Accessions Q9QXW9 Gene names Slc7a8, Lat2
Domain
Architecture
Description Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2).
BAT1_HUMAN
 
NC score 0.107226 (rank : 24) θ value 2.36792 (rank : 29)
Query Neighborhood Hits 46 Target Neighborhood Hits 31 Shared Neighborhood Hits 22
SwissProt Accessions P82251 Gene names SLC7A9, BAT1
Domain
Architecture
Description B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).
CTR4_HUMAN
 
NC score 0.095140 (rank : 25) θ value 0.0736092 (rank : 18)
Query Neighborhood Hits 46 Target Neighborhood Hits 27 Shared Neighborhood Hits 18
SwissProt Accessions O43246, Q3KNQ6, Q4VC45, Q6IBY8, Q96H88 Gene names SLC7A4
Domain
Architecture
Description Cationic amino acid transporter 4 (CAT-4) (CAT4).
AAA1_MOUSE
 
NC score 0.094337 (rank : 26) θ value θ > 10 (rank : 47)
Query Neighborhood Hits 46 Target Neighborhood Hits 31 Shared Neighborhood Hits 23
SwissProt Accessions P63115, Q9CW25, Q9JMH8 Gene names Slc7a10, Asc1
Domain
Architecture

No domain graphic available

Description Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).
AAA1_HUMAN
 
NC score 0.088261 (rank : 27) θ value 0.21417 (rank : 21)
Query Neighborhood Hits 46 Target Neighborhood Hits 25 Shared Neighborhood Hits 19
SwissProt Accessions Q9NS82 Gene names SLC7A10, ASC1
Domain
Architecture
Description Asc-type amino acid transporter 1 (Asc-1).
LAT1_HUMAN
 
NC score 0.066592 (rank : 28) θ value 4.03905 (rank : 34)
Query Neighborhood Hits 46 Target Neighborhood Hits 29 Shared Neighborhood Hits 18
SwissProt Accessions Q01650, Q9UBN8, Q9UP15, Q9UQC0 Gene names SLC7A5, CD98LC, LAT1, MPE16
Domain
Architecture
Description Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain) (Integral membrane protein E16) (hLAT1).
XCT_MOUSE
 
NC score 0.064777 (rank : 29) θ value θ > 10 (rank : 49)
Query Neighborhood Hits 46 Target Neighborhood Hits 23 Shared Neighborhood Hits 18
SwissProt Accessions Q9WTR6 Gene names Slc7a11
Domain
Architecture
Description Cystine/glutamate transporter (Amino acid transport system xc-) (xCT).
YLA1_HUMAN
 
NC score 0.064153 (rank : 30) θ value θ > 10 (rank : 50)
Query Neighborhood Hits 46 Target Neighborhood Hits 27 Shared Neighborhood Hits 17
SwissProt Accessions Q9UM01, O95984, Q9P2V5 Gene names SLC7A7
Domain
Architecture
Description Y+L amino acid transporter 1 (y(+)L-type amino acid transporter 1) (y+LAT-1) (Y+LAT1) (Monocyte amino acid permease 2) (MOP-2).
LAT1_MOUSE
 
NC score 0.062943 (rank : 31) θ value 6.88961 (rank : 41)
Query Neighborhood Hits 46 Target Neighborhood Hits 26 Shared Neighborhood Hits 18
SwissProt Accessions Q9Z127, Q9JMI4 Gene names Slc7a5, Lat1
Domain
Architecture
Description Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC).
XCT_HUMAN
 
NC score 0.058328 (rank : 32) θ value θ > 10 (rank : 48)
Query Neighborhood Hits 46 Target Neighborhood Hits 26 Shared Neighborhood Hits 17
SwissProt Accessions Q9UPY5 Gene names SLC7A11
Domain
Architecture
Description Cystine/glutamate transporter (Amino acid transport system xc-) (xCT) (Calcium channel blocker resistance protein CCBR1).
G137B_HUMAN
 
NC score 0.057629 (rank : 33) θ value 1.06291 (rank : 26)
Query Neighborhood Hits 46 Target Neighborhood Hits 46 Shared Neighborhood Hits 8
SwissProt Accessions O60478 Gene names GPR137B, TM7SF1
Domain
Architecture

No domain graphic available

Description Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).
SETX_HUMAN
 
NC score 0.025824 (rank : 34) θ value 0.125558 (rank : 19)
Query Neighborhood Hits 46 Target Neighborhood Hits 368 Shared Neighborhood Hits 3
SwissProt Accessions Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9 Gene names SETX, ALS4, KIAA0625, SCAR1
Domain
Architecture
Description Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).
MDN1_HUMAN
 
NC score 0.018275 (rank : 35) θ value 4.03905 (rank : 35)
Query Neighborhood Hits 46 Target Neighborhood Hits 662 Shared Neighborhood Hits 5
SwissProt Accessions Q9NU22, O15019 Gene names MDN1, KIAA0301
Domain
Architecture
Description Midasin (MIDAS-containing protein).
CC045_HUMAN
 
NC score 0.013298 (rank : 36) θ value 8.99809 (rank : 43)
Query Neighborhood Hits 46 Target Neighborhood Hits 3 Shared Neighborhood Hits 2
SwissProt Accessions Q8N112 Gene names C3orf45
Domain
Architecture

No domain graphic available

Description Uncharacterized protein C3orf45.
NBEA_HUMAN
 
NC score 0.011643 (rank : 37) θ value 4.03905 (rank : 36)
Query Neighborhood Hits 46 Target Neighborhood Hits 186 Shared Neighborhood Hits 4
SwissProt Accessions Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1 Gene names NBEA, BCL8B, KIAA1544, LYST2
Domain
Architecture
Description Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).
NBEA_MOUSE
 
NC score 0.011537 (rank : 38) θ value 4.03905 (rank : 37)
Query Neighborhood Hits 46 Target Neighborhood Hits 225 Shared Neighborhood Hits 4
SwissProt Accessions Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9 Gene names Nbea, Lyst2
Domain
Architecture
Description Protein neurobeachin (Lysosomal-trafficking regulator 2).
GPR84_HUMAN
 
NC score 0.011048 (rank : 39) θ value 1.38821 (rank : 28)
Query Neighborhood Hits 46 Target Neighborhood Hits 682 Shared Neighborhood Hits 7
SwissProt Accessions Q9NQS5 Gene names GPR84, EX33
Domain
Architecture

No domain graphic available

Description Probable G-protein coupled receptor 84 (Inflammation-related G-protein coupled receptor EX33).
GGH_MOUSE
 
NC score 0.007795 (rank : 40) θ value 8.99809 (rank : 45)
Query Neighborhood Hits 46 Target Neighborhood Hits 4 Shared Neighborhood Hits 2
SwissProt Accessions Q9Z0L8, Q9Z0L7 Gene names Ggh
Domain
Architecture
Description Gamma-glutamyl hydrolase precursor (EC 3.4.19.9) (Gamma-Glu-x carboxypeptidase) (Conjugase) (GH) (Folylpolyglutamate hydrolase) (FGPH).
GCS1_HUMAN
 
NC score 0.006442 (rank : 41) θ value 8.99809 (rank : 44)
Query Neighborhood Hits 46 Target Neighborhood Hits 6 Shared Neighborhood Hits 2
SwissProt Accessions Q13724, Q17RN9, Q8TCT5 Gene names GCS1
Domain
Architecture
Description Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A- glucosidase I).
AFF2_HUMAN
 
NC score 0.005079 (rank : 42) θ value 6.88961 (rank : 39)
Query Neighborhood Hits 46 Target Neighborhood Hits 218 Shared Neighborhood Hits 2
SwissProt Accessions P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5 Gene names AFF2, FMR2, OX19
Domain
Architecture
Description AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).
ADCY6_HUMAN
 
NC score 0.004712 (rank : 43) θ value 5.27518 (rank : 38)
Query Neighborhood Hits 46 Target Neighborhood Hits 52 Shared Neighborhood Hits 4
SwissProt Accessions O43306, Q9NR75 Gene names ADCY6, KIAA0422
Domain
Architecture
Description Adenylate cyclase type 6 (EC 4.6.1.1) (Adenylate cyclase type VI) (ATP pyrophosphate-lyase 6) (Ca(2+)-inhibitable adenylyl cyclase).
CCD11_MOUSE
 
NC score 0.004689 (rank : 44) θ value 3.0926 (rank : 30)
Query Neighborhood Hits 46 Target Neighborhood Hits 498 Shared Neighborhood Hits 4
SwissProt Accessions Q9D439 Gene names Ccdc11
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 11.
ADCY6_MOUSE
 
NC score 0.004024 (rank : 45) θ value 8.99809 (rank : 42)
Query Neighborhood Hits 46 Target Neighborhood Hits 57 Shared Neighborhood Hits 3
SwissProt Accessions Q01341 Gene names Adcy6
Domain
Architecture
Description Adenylate cyclase type 6 (EC 4.6.1.1) (Adenylate cyclase type VI) (ATP pyrophosphate-lyase 6) (Ca(2+)-inhibitable adenylyl cyclase).
PLCB4_HUMAN
 
NC score 0.003786 (rank : 46) θ value 3.0926 (rank : 31)
Query Neighborhood Hits 46 Target Neighborhood Hits 658 Shared Neighborhood Hits 4
SwissProt Accessions Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2 Gene names PLCB4
Domain
Architecture
Description 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).
GPR84_MOUSE
 
NC score 0.003592 (rank : 47) θ value 4.03905 (rank : 33)
Query Neighborhood Hits 46 Target Neighborhood Hits 703 Shared Neighborhood Hits 3
SwissProt Accessions Q8CIM5, Q99MX9 Gene names Gpr84
Domain
Architecture

No domain graphic available

Description Probable G-protein coupled receptor 84.
EDG1_HUMAN
 
NC score 0.003312 (rank : 48) θ value 4.03905 (rank : 32)
Query Neighborhood Hits 46 Target Neighborhood Hits 860 Shared Neighborhood Hits 5
SwissProt Accessions P21453 Gene names EDG1
Domain
Architecture
Description Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1).
CCD19_HUMAN
 
NC score 0.002035 (rank : 49) θ value 6.88961 (rank : 40)
Query Neighborhood Hits 46 Target Neighborhood Hits 639 Shared Neighborhood Hits 4
SwissProt Accessions Q9UL16 Gene names CCDC19, NESG1
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).
ZN510_HUMAN
 
NC score -0.003098 (rank : 50) θ value 8.99809 (rank : 46)
Query Neighborhood Hits 46 Target Neighborhood Hits 764 Shared Neighborhood Hits 2
SwissProt Accessions Q9Y2H8 Gene names ZNF510, KIAA0972
Domain
Architecture
Description Zinc finger protein 510.