Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CTR1_HUMAN

For an explanation of this page, click here

CTR1_HUMAN
SwissProt Accessions	P30825	Gene names	SLC7A1, ATRC1, REC1L
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor homolog) (ERR) (Ecotropic retrovirus receptor homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CTR1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	P30825	Gene names	SLC7A1, ATRC1, REC1L
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor homolog) (ERR) (Ecotropic retrovirus receptor homolog).

CTR1_MOUSE
θ value	0 (rank : 2)	NC score	0.997402 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	Q09143, P30824	Gene names	Slc7a1, Atrc1, Rec-1
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).

CTR2_HUMAN
θ value	0 (rank : 3)	NC score	0.989905 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	P52569	Gene names	SLC7A2, ATRC2
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2).

CTR2_MOUSE
θ value	0 (rank : 4)	NC score	0.989968 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	P18581	Gene names	Slc7a2, Atrc2, Tea
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (TEA protein) (T-cell early activation protein) (20.5).

CTR3_HUMAN
θ value	0 (rank : 5)	NC score	0.990230 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WY07, Q8N185, Q8NCA7, Q96SZ7	Gene names	SLC7A3, ATRC3, CAT3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

CTR3_MOUSE
θ value	4.68096e-182 (rank : 6)	NC score	0.992088 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	P70423	Gene names	Slc7a3, Atrc3, Cat3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

CTR4_HUMAN
θ value	1.34386e-112 (rank : 7)	NC score	0.975678 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	O43246, Q3KNQ6, Q4VC45, Q6IBY8, Q96H88	Gene names	SLC7A4
Domain Architecture
Description	Cationic amino acid transporter 4 (CAT-4) (CAT4).

AAA1_MOUSE
θ value	3.63628e-17 (rank : 8)	NC score	0.599296 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	P63115, Q9CW25, Q9JMH8	Gene names	Slc7a10, Asc1
Domain Architecture	No domain graphic available
Description	Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).

XCT_HUMAN
θ value	1.38178e-16 (rank : 9)	NC score	0.611185 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPY5	Gene names	SLC7A11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT) (Calcium channel blocker resistance protein CCBR1).

BAT1_MOUSE
θ value	5.8054e-15 (rank : 10)	NC score	0.626798 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXA6	Gene names	Slc7a9, Bat1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

XCT_MOUSE
θ value	1.29331e-14 (rank : 11)	NC score	0.609683 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	23	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTR6	Gene names	Slc7a11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT).

BAT1_HUMAN
θ value	8.38298e-14 (rank : 12)	NC score	0.613678 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	P82251	Gene names	SLC7A9, BAT1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

AAA1_HUMAN
θ value	1.42992e-13 (rank : 13)	NC score	0.575500 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS82	Gene names	SLC7A10, ASC1
Domain Architecture
Description	Asc-type amino acid transporter 1 (Asc-1).

LAT1_MOUSE
θ value	1.02475e-11 (rank : 14)	NC score	0.584534 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z127, Q9JMI4	Gene names	Slc7a5, Lat1
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC).

LAT1_HUMAN
θ value	3.89403e-11 (rank : 15)	NC score	0.586199 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q01650, Q9UBN8, Q9UP15, Q9UQC0	Gene names	SLC7A5, CD98LC, LAT1, MPE16
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain) (Integral membrane protein E16) (hLAT1).

LAT2_HUMAN
θ value	5.08577e-11 (rank : 16)	NC score	0.569258 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHI5, Q9UKQ6, Q9UKQ7, Q9UKQ8, Q9Y445	Gene names	SLC7A8, LAT2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2).

LAT2_MOUSE
θ value	5.08577e-11 (rank : 17)	NC score	0.557259 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXW9	Gene names	Slc7a8, Lat2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2).

YLA1_HUMAN
θ value	7.34386e-10 (rank : 18)	NC score	0.584285 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UM01, O95984, Q9P2V5	Gene names	SLC7A7
Domain Architecture
Description	Y+L amino acid transporter 1 (y(+)L-type amino acid transporter 1) (y+LAT-1) (Y+LAT1) (Monocyte amino acid permease 2) (MOP-2).

S12A6_MOUSE
θ value	0.00228821 (rank : 19)	NC score	0.166718 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A6_HUMAN
θ value	0.00509761 (rank : 20)	NC score	0.162649 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A4_MOUSE
θ value	0.0148317 (rank : 21)	NC score	0.160398 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIS8, O55069, Q9ET57	Gene names	Slc12a4, Kcc1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).

S12A4_HUMAN
θ value	0.0252991 (rank : 22)	NC score	0.163014 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UP95, O60632, O75893, Q13953, Q96LD5	Gene names	SLC12A4, KCC1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1).

S12A5_HUMAN
θ value	0.0736092 (rank : 23)	NC score	0.158728 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

S12A7_MOUSE
θ value	0.0736092 (rank : 24)	NC score	0.170440 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	56	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A5_MOUSE
θ value	0.163984 (rank : 25)	NC score	0.155458 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

PIGN_MOUSE
θ value	0.365318 (rank : 26)	NC score	0.028645 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

S12A1_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.133131 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q13621	Gene names	SLC12A1, NKCC2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter).

S12A1_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.133254 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	P55014, O35938, Q91W55, Q9Z1E0	Gene names	Slc12a1, Nkcc2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (BSC1) (Kidney-specific Na-K-Cl symporter).

S12A7_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.149927 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2	Gene names	SLC12A7, KCC4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

AQP9_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.013137 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJJ3	Gene names	Aqp9
Domain Architecture
Description	Aquaporin-9 (AQP-9).

FA11A_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.016008 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFB2, Q96CW3, Q96KE8	Gene names	FAM11A
Domain Architecture	No domain graphic available
Description	Protein FAM11A.

CNR2_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.002325 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	666	Shared Neighborhood Hits	2
SwissProt Accessions	P34972	Gene names	CNR2
Domain Architecture
Description	Cannabinoid receptor 2 (CB2) (CB-2) (CX5).

S12A2_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.108272 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S36A1_MOUSE
θ value	4.03905 (rank : 34)	NC score	0.014482 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4D3, Q811N9	Gene names	Slc36a1, Pat1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

CLPT1_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.018648 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O96005, Q53ET6, Q9BSS5	Gene names	CLPTM1
Domain Architecture	No domain graphic available
Description	Cleft lip and palate transmembrane protein 1.

CLPT1_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.018687 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBZ3, O08708, Q3U758, Q3U823, Q3UG77, Q8VEJ6	Gene names	Clptm1, N14
Domain Architecture	No domain graphic available
Description	Cleft lip and palate transmembrane protein 1 homolog (Thymic epithelial cell surface antigen).

EPHA5_HUMAN
θ value	6.88961 (rank : 37)	NC score	-0.001547 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	1009	Shared Neighborhood Hits	4
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA5_MOUSE
θ value	6.88961 (rank : 38)	NC score	-0.001503 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	950	Shared Neighborhood Hits	4
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

KCNG4_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.004909 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

S12A2_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.103134 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	P55011, Q8N713, Q8WWH7	Gene names	SLC12A2, NKCC1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A3_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.083702 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	P59158	Gene names	Slc12a3, Tsc
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A3_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.084963 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P55017	Gene names	SLC12A3, TSC
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

Hits sorted by NC score

CTR1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	P30825	Gene names	SLC7A1, ATRC1, REC1L
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor homolog) (ERR) (Ecotropic retrovirus receptor homolog).

CTR1_MOUSE
NC score	0.997402 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	Q09143, P30824	Gene names	Slc7a1, Atrc1, Rec-1
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).

CTR3_MOUSE
NC score	0.992088 (rank : 3)	θ value	4.68096e-182 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	P70423	Gene names	Slc7a3, Atrc3, Cat3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

CTR3_HUMAN
NC score	0.990230 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WY07, Q8N185, Q8NCA7, Q96SZ7	Gene names	SLC7A3, ATRC3, CAT3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

CTR2_MOUSE
NC score	0.989968 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	P18581	Gene names	Slc7a2, Atrc2, Tea
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (TEA protein) (T-cell early activation protein) (20.5).

CTR2_HUMAN
NC score	0.989905 (rank : 6)	θ value	0 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	P52569	Gene names	SLC7A2, ATRC2
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2).

CTR4_HUMAN
NC score	0.975678 (rank : 7)	θ value	1.34386e-112 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	O43246, Q3KNQ6, Q4VC45, Q6IBY8, Q96H88	Gene names	SLC7A4
Domain Architecture
Description	Cationic amino acid transporter 4 (CAT-4) (CAT4).

BAT1_MOUSE
NC score	0.626798 (rank : 8)	θ value	5.8054e-15 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXA6	Gene names	Slc7a9, Bat1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

BAT1_HUMAN
NC score	0.613678 (rank : 9)	θ value	8.38298e-14 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	P82251	Gene names	SLC7A9, BAT1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

XCT_HUMAN
NC score	0.611185 (rank : 10)	θ value	1.38178e-16 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPY5	Gene names	SLC7A11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT) (Calcium channel blocker resistance protein CCBR1).

XCT_MOUSE
NC score	0.609683 (rank : 11)	θ value	1.29331e-14 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	23	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTR6	Gene names	Slc7a11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT).

AAA1_MOUSE
NC score	0.599296 (rank : 12)	θ value	3.63628e-17 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	P63115, Q9CW25, Q9JMH8	Gene names	Slc7a10, Asc1
Domain Architecture	No domain graphic available
Description	Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).

LAT1_HUMAN
NC score	0.586199 (rank : 13)	θ value	3.89403e-11 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q01650, Q9UBN8, Q9UP15, Q9UQC0	Gene names	SLC7A5, CD98LC, LAT1, MPE16
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain) (Integral membrane protein E16) (hLAT1).

LAT1_MOUSE
NC score	0.584534 (rank : 14)	θ value	1.02475e-11 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z127, Q9JMI4	Gene names	Slc7a5, Lat1
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC).

YLA1_HUMAN
NC score	0.584285 (rank : 15)	θ value	7.34386e-10 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UM01, O95984, Q9P2V5	Gene names	SLC7A7
Domain Architecture
Description	Y+L amino acid transporter 1 (y(+)L-type amino acid transporter 1) (y+LAT-1) (Y+LAT1) (Monocyte amino acid permease 2) (MOP-2).

AAA1_HUMAN
NC score	0.575500 (rank : 16)	θ value	1.42992e-13 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS82	Gene names	SLC7A10, ASC1
Domain Architecture
Description	Asc-type amino acid transporter 1 (Asc-1).

LAT2_HUMAN
NC score	0.569258 (rank : 17)	θ value	5.08577e-11 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHI5, Q9UKQ6, Q9UKQ7, Q9UKQ8, Q9Y445	Gene names	SLC7A8, LAT2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2).

LAT2_MOUSE
NC score	0.557259 (rank : 18)	θ value	5.08577e-11 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXW9	Gene names	Slc7a8, Lat2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2).

S12A7_MOUSE
NC score	0.170440 (rank : 19)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	56	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A6_MOUSE
NC score	0.166718 (rank : 20)	θ value	0.00228821 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A4_HUMAN
NC score	0.163014 (rank : 21)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UP95, O60632, O75893, Q13953, Q96LD5	Gene names	SLC12A4, KCC1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1).

S12A6_HUMAN
NC score	0.162649 (rank : 22)	θ value	0.00509761 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A4_MOUSE
NC score	0.160398 (rank : 23)	θ value	0.0148317 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIS8, O55069, Q9ET57	Gene names	Slc12a4, Kcc1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).

S12A5_HUMAN
NC score	0.158728 (rank : 24)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

S12A5_MOUSE
NC score	0.155458 (rank : 25)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

S12A7_HUMAN
NC score	0.149927 (rank : 26)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2	Gene names	SLC12A7, KCC4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A1_MOUSE
NC score	0.133254 (rank : 27)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	P55014, O35938, Q91W55, Q9Z1E0	Gene names	Slc12a1, Nkcc2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (BSC1) (Kidney-specific Na-K-Cl symporter).

S12A1_HUMAN
NC score	0.133131 (rank : 28)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q13621	Gene names	SLC12A1, NKCC2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter).

S12A2_MOUSE
NC score	0.108272 (rank : 29)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A2_HUMAN
NC score	0.103134 (rank : 30)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	P55011, Q8N713, Q8WWH7	Gene names	SLC12A2, NKCC1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A3_HUMAN
NC score	0.084963 (rank : 31)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P55017	Gene names	SLC12A3, TSC
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A3_MOUSE
NC score	0.083702 (rank : 32)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	P59158	Gene names	Slc12a3, Tsc
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

PIGN_MOUSE
NC score	0.028645 (rank : 33)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1S3, Q3V0S6, Q8VCC3, Q9R1S1, Q9R1S2	Gene names	Pign
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N).

CLPT1_MOUSE
NC score	0.018687 (rank : 34)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBZ3, O08708, Q3U758, Q3U823, Q3UG77, Q8VEJ6	Gene names	Clptm1, N14
Domain Architecture	No domain graphic available
Description	Cleft lip and palate transmembrane protein 1 homolog (Thymic epithelial cell surface antigen).

CLPT1_HUMAN
NC score	0.018648 (rank : 35)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O96005, Q53ET6, Q9BSS5	Gene names	CLPTM1
Domain Architecture	No domain graphic available
Description	Cleft lip and palate transmembrane protein 1.

FA11A_HUMAN
NC score	0.016008 (rank : 36)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFB2, Q96CW3, Q96KE8	Gene names	FAM11A
Domain Architecture	No domain graphic available
Description	Protein FAM11A.

S36A1_MOUSE
NC score	0.014482 (rank : 37)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4D3, Q811N9	Gene names	Slc36a1, Pat1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

AQP9_MOUSE
NC score	0.013137 (rank : 38)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJJ3	Gene names	Aqp9
Domain Architecture
Description	Aquaporin-9 (AQP-9).

KCNG4_HUMAN
NC score	0.004909 (rank : 39)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

CNR2_HUMAN
NC score	0.002325 (rank : 40)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	666	Shared Neighborhood Hits	2
SwissProt Accessions	P34972	Gene names	CNR2
Domain Architecture
Description	Cannabinoid receptor 2 (CB2) (CB-2) (CX5).

EPHA5_MOUSE
NC score	-0.001503 (rank : 41)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	950	Shared Neighborhood Hits	4
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHA5_HUMAN
NC score	-0.001547 (rank : 42)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	1009	Shared Neighborhood Hits	4
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).