Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : S12A1_HUMAN

For an explanation of this page, click here

S12A1_HUMAN
SwissProt Accessions	Q13621	Gene names	SLC12A1, NKCC2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

S12A1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	28	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q13621	Gene names	SLC12A1, NKCC2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter).

S12A1_MOUSE
θ value	0 (rank : 2)	NC score	0.999567 (rank : 2)
Query Neighborhood Hits	28	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	P55014, O35938, Q91W55, Q9Z1E0	Gene names	Slc12a1, Nkcc2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (BSC1) (Kidney-specific Na-K-Cl symporter).

S12A2_HUMAN
θ value	0 (rank : 3)	NC score	0.992813 (rank : 4)
Query Neighborhood Hits	28	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	P55011, Q8N713, Q8WWH7	Gene names	SLC12A2, NKCC1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A2_MOUSE
θ value	0 (rank : 4)	NC score	0.993039 (rank : 3)
Query Neighborhood Hits	28	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A3_HUMAN
θ value	0 (rank : 5)	NC score	0.990027 (rank : 5)
Query Neighborhood Hits	28	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	P55017	Gene names	SLC12A3, TSC
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A3_MOUSE
θ value	0 (rank : 6)	NC score	0.987351 (rank : 6)
Query Neighborhood Hits	28	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	P59158	Gene names	Slc12a3, Tsc
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A7_MOUSE
θ value	1.08223e-53 (rank : 7)	NC score	0.807788 (rank : 8)
Query Neighborhood Hits	28	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A7_HUMAN
θ value	1.41344e-53 (rank : 8)	NC score	0.810717 (rank : 7)
Query Neighborhood Hits	28	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2	Gene names	SLC12A7, KCC4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A5_HUMAN
θ value	3.48141e-52 (rank : 9)	NC score	0.804567 (rank : 11)
Query Neighborhood Hits	28	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

S12A5_MOUSE
θ value	4.54686e-52 (rank : 10)	NC score	0.804345 (rank : 12)
Query Neighborhood Hits	28	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

S12A4_MOUSE
θ value	2.94719e-51 (rank : 11)	NC score	0.805675 (rank : 9)
Query Neighborhood Hits	28	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIS8, O55069, Q9ET57	Gene names	Slc12a4, Kcc1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).

S12A6_HUMAN
θ value	3.84914e-51 (rank : 12)	NC score	0.801784 (rank : 13)
Query Neighborhood Hits	28	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A4_HUMAN
θ value	5.02714e-51 (rank : 13)	NC score	0.804895 (rank : 10)
Query Neighborhood Hits	28	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UP95, O60632, O75893, Q13953, Q96LD5	Gene names	SLC12A4, KCC1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1).

S12A6_MOUSE
θ value	8.57503e-51 (rank : 14)	NC score	0.801123 (rank : 14)
Query Neighborhood Hits	28	Target Neighborhood Hits	67	Shared Neighborhood Hits	20
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

CTR2_MOUSE
θ value	0.00175202 (rank : 15)	NC score	0.182895 (rank : 15)
Query Neighborhood Hits	28	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	P18581	Gene names	Slc7a2, Atrc2, Tea
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (TEA protein) (T-cell early activation protein) (20.5).

CTR1_MOUSE
θ value	0.00228821 (rank : 16)	NC score	0.168570 (rank : 16)
Query Neighborhood Hits	28	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q09143, P30824	Gene names	Slc7a1, Atrc1, Rec-1
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).

XCT_MOUSE
θ value	0.00665767 (rank : 17)	NC score	0.071987 (rank : 26)
Query Neighborhood Hits	28	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTR6	Gene names	Slc7a11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT).

CTR3_MOUSE
θ value	0.00869519 (rank : 18)	NC score	0.126443 (rank : 19)
Query Neighborhood Hits	28	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	P70423	Gene names	Slc7a3, Atrc3, Cat3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

CTR2_HUMAN
θ value	0.0113563 (rank : 19)	NC score	0.168094 (rank : 17)
Query Neighborhood Hits	28	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	P52569	Gene names	SLC7A2, ATRC2
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2).

AAA1_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.089649 (rank : 21)
Query Neighborhood Hits	28	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	P63115, Q9CW25, Q9JMH8	Gene names	Slc7a10, Asc1
Domain Architecture	No domain graphic available
Description	Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).

CTR1_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.133131 (rank : 18)
Query Neighborhood Hits	28	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	P30825	Gene names	SLC7A1, ATRC1, REC1L
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor homolog) (ERR) (Ecotropic retrovirus receptor homolog).

XCT_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.058425 (rank : 28)
Query Neighborhood Hits	28	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPY5	Gene names	SLC7A11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT) (Calcium channel blocker resistance protein CCBR1).

OLF15_MOUSE
θ value	1.81305 (rank : 23)	NC score	-0.000037 (rank : 34)
Query Neighborhood Hits	28	Target Neighborhood Hits	752	Shared Neighborhood Hits	5
SwissProt Accessions	P23275	Gene names	Olfr15
Domain Architecture
Description	Olfactory receptor 15 (Odorant receptor OR3).

SLC2B_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.017136 (rank : 30)
Query Neighborhood Hits	28	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

MRCKB_HUMAN
θ value	6.88961 (rank : 25)	NC score	-0.003638 (rank : 35)
Query Neighborhood Hits	28	Target Neighborhood Hits	2239	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYH14_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.002010 (rank : 32)
Query Neighborhood Hits	28	Target Neighborhood Hits	1225	Shared Neighborhood Hits	4
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

S6A11_HUMAN
θ value	8.99809 (rank : 27)	NC score	0.001454 (rank : 33)
Query Neighborhood Hits	28	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	P48066	Gene names	SLC6A11, GABT3, GAT3
Domain Architecture
Description	Sodium- and chloride-dependent GABA transporter 3.

TAK1L_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.013680 (rank : 31)
Query Neighborhood Hits	28	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

AAA1_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.055361 (rank : 29)
Query Neighborhood Hits	28	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NS82	Gene names	SLC7A10, ASC1
Domain Architecture
Description	Asc-type amino acid transporter 1 (Asc-1).

BAT1_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.066453 (rank : 27)
Query Neighborhood Hits	28	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	P82251	Gene names	SLC7A9, BAT1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

BAT1_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.076677 (rank : 24)
Query Neighborhood Hits	28	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXA6	Gene names	Slc7a9, Bat1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

CTR3_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.104245 (rank : 20)
Query Neighborhood Hits	28	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WY07, Q8N185, Q8NCA7, Q96SZ7	Gene names	SLC7A3, ATRC3, CAT3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

CTR4_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.080462 (rank : 22)
Query Neighborhood Hits	28	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	O43246, Q3KNQ6, Q4VC45, Q6IBY8, Q96H88	Gene names	SLC7A4
Domain Architecture
Description	Cationic amino acid transporter 4 (CAT-4) (CAT4).

LAT2_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.076438 (rank : 25)
Query Neighborhood Hits	28	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHI5, Q9UKQ6, Q9UKQ7, Q9UKQ8, Q9Y445	Gene names	SLC7A8, LAT2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2).

LAT2_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.078682 (rank : 23)
Query Neighborhood Hits	28	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXW9	Gene names	Slc7a8, Lat2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2).

Hits sorted by NC score

S12A1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	28	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q13621	Gene names	SLC12A1, NKCC2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter).

S12A1_MOUSE
NC score	0.999567 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	28	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	P55014, O35938, Q91W55, Q9Z1E0	Gene names	Slc12a1, Nkcc2
Domain Architecture
Description	Solute carrier family 12 member 1 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2) (BSC1) (Kidney-specific Na-K-Cl symporter).

S12A2_MOUSE
NC score	0.993039 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	28	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A2_HUMAN
NC score	0.992813 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	28	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	P55011, Q8N713, Q8WWH7	Gene names	SLC12A2, NKCC1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

S12A3_HUMAN
NC score	0.990027 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	28	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	P55017	Gene names	SLC12A3, TSC
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A3_MOUSE
NC score	0.987351 (rank : 6)	θ value	0 (rank : 6)
Query Neighborhood Hits	28	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	P59158	Gene names	Slc12a3, Tsc
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

S12A7_HUMAN
NC score	0.810717 (rank : 7)	θ value	1.41344e-53 (rank : 8)
Query Neighborhood Hits	28	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y666, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2	Gene names	SLC12A7, KCC4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A7_MOUSE
NC score	0.807788 (rank : 8)	θ value	1.08223e-53 (rank : 7)
Query Neighborhood Hits	28	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WVL3	Gene names	Slc12a7, Kcc4
Domain Architecture
Description	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4).

S12A4_MOUSE
NC score	0.805675 (rank : 9)	θ value	2.94719e-51 (rank : 11)
Query Neighborhood Hits	28	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIS8, O55069, Q9ET57	Gene names	Slc12a4, Kcc1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).

S12A4_HUMAN
NC score	0.804895 (rank : 10)	θ value	5.02714e-51 (rank : 13)
Query Neighborhood Hits	28	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UP95, O60632, O75893, Q13953, Q96LD5	Gene names	SLC12A4, KCC1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1).

S12A5_HUMAN
NC score	0.804567 (rank : 11)	θ value	3.48141e-52 (rank : 9)
Query Neighborhood Hits	28	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H2X9, Q5VZ41, Q9H4Z0, Q9ULP4	Gene names	SLC12A5, KCC2, KIAA1176
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Erythroid K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).

S12A5_MOUSE
NC score	0.804345 (rank : 12)	θ value	4.54686e-52 (rank : 10)
Query Neighborhood Hits	28	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q91V14, Q9Z0M7	Gene names	Slc12a5, Kcc2
Domain Architecture
Description	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (Neuronal K-Cl cotransporter) (mKCC2).

S12A6_HUMAN
NC score	0.801784 (rank : 13)	θ value	3.84914e-51 (rank : 12)
Query Neighborhood Hits	28	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHW9, Q8TDD4, Q9UFR2, Q9Y642, Q9Y665	Gene names	SLC12A6, KCC3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

S12A6_MOUSE
NC score	0.801123 (rank : 14)	θ value	8.57503e-51 (rank : 14)
Query Neighborhood Hits	28	Target Neighborhood Hits	67	Shared Neighborhood Hits	20
SwissProt Accessions	Q924N4, Q924N3	Gene names	Slc12a6, Kcc3
Domain Architecture
Description	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3).

CTR2_MOUSE
NC score	0.182895 (rank : 15)	θ value	0.00175202 (rank : 15)
Query Neighborhood Hits	28	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	P18581	Gene names	Slc7a2, Atrc2, Tea
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (TEA protein) (T-cell early activation protein) (20.5).

CTR1_MOUSE
NC score	0.168570 (rank : 16)	θ value	0.00228821 (rank : 16)
Query Neighborhood Hits	28	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q09143, P30824	Gene names	Slc7a1, Atrc1, Rec-1
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor) (ERR) (Ecotropic retrovirus receptor).

CTR2_HUMAN
NC score	0.168094 (rank : 17)	θ value	0.0113563 (rank : 19)
Query Neighborhood Hits	28	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	P52569	Gene names	SLC7A2, ATRC2
Domain Architecture
Description	Low-affinity cationic amino acid transporter 2 (CAT-2) (CAT2).

CTR1_HUMAN
NC score	0.133131 (rank : 18)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	28	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	P30825	Gene names	SLC7A1, ATRC1, REC1L
Domain Architecture
Description	High-affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (System Y+ basic amino acid transporter) (Ecotropic retroviral leukemia receptor homolog) (ERR) (Ecotropic retrovirus receptor homolog).

CTR3_MOUSE
NC score	0.126443 (rank : 19)	θ value	0.00869519 (rank : 18)
Query Neighborhood Hits	28	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	P70423	Gene names	Slc7a3, Atrc3, Cat3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

CTR3_HUMAN
NC score	0.104245 (rank : 20)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	28	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WY07, Q8N185, Q8NCA7, Q96SZ7	Gene names	SLC7A3, ATRC3, CAT3
Domain Architecture
Description	Cationic amino acid transporter 3 (CAT-3) (Solute carrier family 7 member 3) (Cationic amino acid transporter y+).

AAA1_MOUSE
NC score	0.089649 (rank : 21)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	28	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	P63115, Q9CW25, Q9JMH8	Gene names	Slc7a10, Asc1
Domain Architecture	No domain graphic available
Description	Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).

CTR4_HUMAN
NC score	0.080462 (rank : 22)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	28	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	O43246, Q3KNQ6, Q4VC45, Q6IBY8, Q96H88	Gene names	SLC7A4
Domain Architecture
Description	Cationic amino acid transporter 4 (CAT-4) (CAT4).

LAT2_MOUSE
NC score	0.078682 (rank : 23)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	28	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXW9	Gene names	Slc7a8, Lat2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2).

BAT1_MOUSE
NC score	0.076677 (rank : 24)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	28	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXA6	Gene names	Slc7a9, Bat1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

LAT2_HUMAN
NC score	0.076438 (rank : 25)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	28	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHI5, Q9UKQ6, Q9UKQ7, Q9UKQ8, Q9Y445	Gene names	SLC7A8, LAT2
Domain Architecture
Description	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2).

XCT_MOUSE
NC score	0.071987 (rank : 26)	θ value	0.00665767 (rank : 17)
Query Neighborhood Hits	28	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTR6	Gene names	Slc7a11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT).

BAT1_HUMAN
NC score	0.066453 (rank : 27)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	28	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	P82251	Gene names	SLC7A9, BAT1
Domain Architecture
Description	B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein- associated amino acid transporter b0,+AT1).

XCT_HUMAN
NC score	0.058425 (rank : 28)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	28	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPY5	Gene names	SLC7A11
Domain Architecture
Description	Cystine/glutamate transporter (Amino acid transport system xc-) (xCT) (Calcium channel blocker resistance protein CCBR1).

AAA1_HUMAN
NC score	0.055361 (rank : 29)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	28	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NS82	Gene names	SLC7A10, ASC1
Domain Architecture
Description	Asc-type amino acid transporter 1 (Asc-1).

SLC2B_HUMAN
NC score	0.017136 (rank : 30)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	28	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

TAK1L_HUMAN
NC score	0.013680 (rank : 31)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	28	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

MYH14_MOUSE
NC score	0.002010 (rank : 32)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	28	Target Neighborhood Hits	1225	Shared Neighborhood Hits	4
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

S6A11_HUMAN
NC score	0.001454 (rank : 33)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	28	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	P48066	Gene names	SLC6A11, GABT3, GAT3
Domain Architecture
Description	Sodium- and chloride-dependent GABA transporter 3.

OLF15_MOUSE
NC score	-0.000037 (rank : 34)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	28	Target Neighborhood Hits	752	Shared Neighborhood Hits	5
SwissProt Accessions	P23275	Gene names	Olfr15
Domain Architecture
Description	Olfactory receptor 15 (Odorant receptor OR3).

MRCKB_HUMAN
NC score	-0.003638 (rank : 35)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	28	Target Neighborhood Hits	2239	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).