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Network neighborhood for query Sequence : MPIP3_HUMAN

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MPIP3_HUMAN
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MPIP3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

MPIP3_MOUSE
θ value	1.05253e-149 (rank : 2)	NC score	0.987837 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	P48967, Q99KG6	Gene names	Cdc25c, Cdc25m1
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

MPIP2_HUMAN
θ value	1.27248e-70 (rank : 3)	NC score	0.932946 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P30305, O43551, Q13971, Q5JX77, Q6RSS1, Q9BRA6	Gene names	CDC25B, CDC25HU2
Domain Architecture
Description	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B).

MPIP2_MOUSE
θ value	1.83746e-69 (rank : 4)	NC score	0.926784 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	P30306, Q99LP3	Gene names	Cdc25b, Cdc25m2
Domain Architecture
Description	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B).

MPIP1_HUMAN
θ value	7.71989e-68 (rank : 5)	NC score	0.922894 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P30304, Q8IZH5, Q96IL3, Q9H2F2	Gene names	CDC25A
Domain Architecture
Description	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A).

MPIP1_MOUSE
θ value	1.6097e-65 (rank : 6)	NC score	0.926009 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	P48964	Gene names	Cdc25a, Cdc25m3
Domain Architecture
Description	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A).

MAP1A_HUMAN
θ value	0.125558 (rank : 7)	NC score	0.025672 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	1626	Shared Neighborhood Hits	7
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

DPOLM_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.032308 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP87	Gene names	POLM
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

DUS5_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.061850 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

SSH1_MOUSE
θ value	0.62314 (rank : 10)	NC score	0.025916 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

FSTL4_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.023179 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	333	Shared Neighborhood Hits	3
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

PTN14_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.011071 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

FSTL4_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.021263 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

DDX25_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.006847 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

HS90A_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.031674 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	155	Shared Neighborhood Hits	7
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

HS90B_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.031126 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

CENPM_MOUSE
θ value	4.03905 (rank : 17)	NC score	0.025670 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQA0, Q3THN3, Q91VS6	Gene names	Cenpm, Pane1
Domain Architecture	No domain graphic available
Description	Centromere protein M (CENP-M) (Proliferation-associated nuclear element protein 1).

DUS4_MOUSE
θ value	4.03905 (rank : 18)	NC score	0.036051 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

GOGB1_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.003384 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	2297	Shared Neighborhood Hits	6
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

PHLB2_MOUSE
θ value	4.03905 (rank : 20)	NC score	0.008716 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	1016	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

HS90A_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.029393 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90B_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.029898 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

AL2SE_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.009695 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NDH6, Q53P45, Q53QZ4, Q53T97, Q96N47, Q96Q32, Q9BVQ2	Gene names	ALS2CR15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein.

DUS4_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.033789 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

Hits sorted by NC score

MPIP3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

MPIP3_MOUSE
NC score	0.987837 (rank : 2)	θ value	1.05253e-149 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	P48967, Q99KG6	Gene names	Cdc25c, Cdc25m1
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

MPIP2_HUMAN
NC score	0.932946 (rank : 3)	θ value	1.27248e-70 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P30305, O43551, Q13971, Q5JX77, Q6RSS1, Q9BRA6	Gene names	CDC25B, CDC25HU2
Domain Architecture
Description	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B).

MPIP2_MOUSE
NC score	0.926784 (rank : 4)	θ value	1.83746e-69 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	P30306, Q99LP3	Gene names	Cdc25b, Cdc25m2
Domain Architecture
Description	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B).

MPIP1_MOUSE
NC score	0.926009 (rank : 5)	θ value	1.6097e-65 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	P48964	Gene names	Cdc25a, Cdc25m3
Domain Architecture
Description	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A).

MPIP1_HUMAN
NC score	0.922894 (rank : 6)	θ value	7.71989e-68 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P30304, Q8IZH5, Q96IL3, Q9H2F2	Gene names	CDC25A
Domain Architecture
Description	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A).

DUS5_HUMAN
NC score	0.061850 (rank : 7)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS4_MOUSE
NC score	0.036051 (rank : 8)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS4_HUMAN
NC score	0.033789 (rank : 9)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DPOLM_HUMAN
NC score	0.032308 (rank : 10)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP87	Gene names	POLM
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

HS90A_MOUSE
NC score	0.031674 (rank : 11)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	155	Shared Neighborhood Hits	7
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

HS90B_MOUSE
NC score	0.031126 (rank : 12)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

HS90B_HUMAN
NC score	0.029898 (rank : 13)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90A_HUMAN
NC score	0.029393 (rank : 14)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

SSH1_MOUSE
NC score	0.025916 (rank : 15)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

MAP1A_HUMAN
NC score	0.025672 (rank : 16)	θ value	0.125558 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	1626	Shared Neighborhood Hits	7
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CENPM_MOUSE
NC score	0.025670 (rank : 17)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQA0, Q3THN3, Q91VS6	Gene names	Cenpm, Pane1
Domain Architecture	No domain graphic available
Description	Centromere protein M (CENP-M) (Proliferation-associated nuclear element protein 1).

FSTL4_MOUSE
NC score	0.023179 (rank : 18)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	333	Shared Neighborhood Hits	3
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL4_HUMAN
NC score	0.021263 (rank : 19)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

PTN14_HUMAN
NC score	0.011071 (rank : 20)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

AL2SE_HUMAN
NC score	0.009695 (rank : 21)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NDH6, Q53P45, Q53QZ4, Q53T97, Q96N47, Q96Q32, Q9BVQ2	Gene names	ALS2CR15
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein.

PHLB2_MOUSE
NC score	0.008716 (rank : 22)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	1016	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

DDX25_MOUSE
NC score	0.006847 (rank : 23)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

GOGB1_HUMAN
NC score	0.003384 (rank : 24)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	2297	Shared Neighborhood Hits	6
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).