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Network neighborhood for query Sequence : PTN14_HUMAN

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PTN14_HUMAN
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTN14_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	0 (rank : 2)	NC score	0.998574 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	142	Shared Neighborhood Hits	120
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN21_HUMAN
θ value	0 (rank : 3)	NC score	0.993803 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	107
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	0 (rank : 4)	NC score	0.992940 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	155	Shared Neighborhood Hits	104
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN3_HUMAN
θ value	1.51013e-55 (rank : 5)	NC score	0.926253 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	258	Shared Neighborhood Hits	113
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
θ value	4.54686e-52 (rank : 6)	NC score	0.916968 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	303	Shared Neighborhood Hits	113
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN6_MOUSE
θ value	4.122e-45 (rank : 7)	NC score	0.768699 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN13_MOUSE
θ value	3.48949e-44 (rank : 8)	NC score	0.814564 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	426	Shared Neighborhood Hits	116
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN6_HUMAN
θ value	3.48949e-44 (rank : 9)	NC score	0.770632 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	234	Shared Neighborhood Hits	69
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN13_HUMAN
θ value	1.91475e-42 (rank : 10)	NC score	0.804429 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	471	Shared Neighborhood Hits	112
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTPRS_HUMAN
θ value	4.2656e-42 (rank : 11)	NC score	0.577840 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	472	Shared Neighborhood Hits	71
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

CD45_MOUSE
θ value	9.50281e-42 (rank : 12)	NC score	0.796206 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	178	Shared Neighborhood Hits	68
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRD_HUMAN
θ value	1.2411e-41 (rank : 13)	NC score	0.567218 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	485	Shared Neighborhood Hits	74
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CD45_HUMAN
θ value	8.04462e-41 (rank : 14)	NC score	0.789644 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	243	Shared Neighborhood Hits	67
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTN9_HUMAN
θ value	1.05066e-40 (rank : 15)	NC score	0.802868 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	1.3722e-40 (rank : 16)	NC score	0.802888 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	78	Shared Neighborhood Hits	65
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPRF_HUMAN
θ value	7.52953e-39 (rank : 17)	NC score	0.563198 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	489	Shared Neighborhood Hits	71
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
θ value	1.28434e-38 (rank : 18)	NC score	0.557496 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTN1_HUMAN
θ value	2.19075e-38 (rank : 19)	NC score	0.816209 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	84	Shared Neighborhood Hits	66
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN11_HUMAN
θ value	2.86122e-38 (rank : 20)	NC score	0.747171 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	3.73686e-38 (rank : 21)	NC score	0.747107 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN1_MOUSE
θ value	6.37413e-38 (rank : 22)	NC score	0.816625 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTPRB_HUMAN
θ value	1.08726e-37 (rank : 23)	NC score	0.743373 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	242	Shared Neighborhood Hits	70
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTN2_MOUSE
θ value	1.85459e-37 (rank : 24)	NC score	0.814854 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTPRA_HUMAN
θ value	7.04741e-37 (rank : 25)	NC score	0.789994 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	101	Shared Neighborhood Hits	67
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRZ_HUMAN
θ value	7.04741e-37 (rank : 26)	NC score	0.714896 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	65
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTN2_HUMAN
θ value	9.20422e-37 (rank : 27)	NC score	0.813852 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	92	Shared Neighborhood Hits	63
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN22_HUMAN
θ value	1.20211e-36 (rank : 28)	NC score	0.805465 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTPRA_MOUSE
θ value	1.57e-36 (rank : 29)	NC score	0.789610 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTN18_HUMAN
θ value	4.568e-36 (rank : 30)	NC score	0.813641 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTPRG_HUMAN
θ value	2.26708e-35 (rank : 31)	NC score	0.713428 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	231	Shared Neighborhood Hits	69
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRE_HUMAN
θ value	2.96089e-35 (rank : 32)	NC score	0.788899 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRG_MOUSE
θ value	2.96089e-35 (rank : 33)	NC score	0.711041 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	260	Shared Neighborhood Hits	70
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRK_MOUSE
θ value	2.96089e-35 (rank : 34)	NC score	0.733378 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	223	Shared Neighborhood Hits	68
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRJ_HUMAN
θ value	5.0505e-35 (rank : 35)	NC score	0.769050 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	207	Shared Neighborhood Hits	73
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRK_HUMAN
θ value	5.0505e-35 (rank : 36)	NC score	0.734842 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTN22_MOUSE
θ value	6.59618e-35 (rank : 37)	NC score	0.798316 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	179	Shared Neighborhood Hits	68
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPRJ_MOUSE
θ value	8.61488e-35 (rank : 38)	NC score	0.772728 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	188	Shared Neighborhood Hits	73
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRV_MOUSE
θ value	1.46948e-34 (rank : 39)	NC score	0.765507 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	179	Shared Neighborhood Hits	66
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRE_MOUSE
θ value	5.584e-34 (rank : 40)	NC score	0.788335 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTN18_MOUSE
θ value	1.6247e-33 (rank : 41)	NC score	0.809580 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	68
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN7_MOUSE
θ value	2.12192e-33 (rank : 42)	NC score	0.808414 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTPRT_HUMAN
θ value	2.12192e-33 (rank : 43)	NC score	0.728163 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	217	Shared Neighborhood Hits	65
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	2.12192e-33 (rank : 44)	NC score	0.728166 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTN12_HUMAN
θ value	8.06329e-33 (rank : 45)	NC score	0.801900 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTPRM_MOUSE
θ value	8.06329e-33 (rank : 46)	NC score	0.716920 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	238	Shared Neighborhood Hits	67
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTN7_HUMAN
θ value	1.79631e-32 (rank : 47)	NC score	0.807658 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTPRM_HUMAN
θ value	3.06405e-32 (rank : 48)	NC score	0.714989 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	244	Shared Neighborhood Hits	67
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRO_HUMAN
θ value	3.06405e-32 (rank : 49)	NC score	0.795503 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	139	Shared Neighborhood Hits	74
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTN12_MOUSE
θ value	5.22648e-32 (rank : 50)	NC score	0.801147 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	123	Shared Neighborhood Hits	67
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

E41L5_HUMAN
θ value	7.54701e-31 (rank : 51)	NC score	0.602676 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41L2_HUMAN
θ value	1.6813e-30 (rank : 52)	NC score	0.582837 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	287	Shared Neighborhood Hits	51
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L1_HUMAN
θ value	2.86786e-30 (rank : 53)	NC score	0.588047 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

PTPRU_HUMAN
θ value	3.74554e-30 (rank : 54)	NC score	0.720022 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	237	Shared Neighborhood Hits	66
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

E41L2_MOUSE
θ value	4.89182e-30 (rank : 55)	NC score	0.567816 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	459	Shared Neighborhood Hits	51
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L1_MOUSE
θ value	6.38894e-30 (rank : 56)	NC score	0.590887 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

PTPRR_MOUSE
θ value	8.3442e-30 (rank : 57)	NC score	0.794059 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

E41LA_HUMAN
θ value	1.85889e-29 (rank : 58)	NC score	0.604937 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

PTPR2_MOUSE
θ value	4.14116e-29 (rank : 59)	NC score	0.787238 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

E41L3_MOUSE
θ value	7.06379e-29 (rank : 60)	NC score	0.583675 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41LB_HUMAN
θ value	7.06379e-29 (rank : 61)	NC score	0.596979 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

PTN23_HUMAN
θ value	9.2256e-29 (rank : 62)	NC score	0.697356 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	646	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRR_HUMAN
θ value	9.2256e-29 (rank : 63)	NC score	0.793259 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

E41L3_HUMAN
θ value	1.2049e-28 (rank : 64)	NC score	0.593210 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

PTN23_MOUSE
θ value	1.2049e-28 (rank : 65)	NC score	0.695384 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	726	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

E41LB_MOUSE
θ value	1.57365e-28 (rank : 66)	NC score	0.603658 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

41_HUMAN
θ value	2.68423e-28 (rank : 67)	NC score	0.590655 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

PTN5_MOUSE
θ value	4.57862e-28 (rank : 68)	NC score	0.797850 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
θ value	5.97985e-28 (rank : 69)	NC score	0.797364 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRN_MOUSE
θ value	5.97985e-28 (rank : 70)	NC score	0.781319 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	68
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

E41LA_MOUSE
θ value	7.80994e-28 (rank : 71)	NC score	0.604834 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	85	Shared Neighborhood Hits	49
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

PTPR2_HUMAN
θ value	1.02001e-27 (rank : 72)	NC score	0.788106 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPRN_HUMAN
θ value	1.33217e-27 (rank : 73)	NC score	0.784457 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

FRMD5_HUMAN
θ value	6.61148e-27 (rank : 74)	NC score	0.601457 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_MOUSE
θ value	8.63488e-27 (rank : 75)	NC score	0.602451 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

41_MOUSE
θ value	9.54697e-26 (rank : 76)	NC score	0.586777 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

FARP2_MOUSE
θ value	2.35151e-24 (rank : 77)	NC score	0.473060 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MERL_HUMAN
θ value	1.16704e-23 (rank : 78)	NC score	0.519867 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	532	Shared Neighborhood Hits	55
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	1.5242e-23 (rank : 79)	NC score	0.520275 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	524	Shared Neighborhood Hits	55
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MYLIP_MOUSE
θ value	5.79196e-23 (rank : 80)	NC score	0.568921 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRM4B_MOUSE
θ value	7.56453e-23 (rank : 81)	NC score	0.548072 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FARP1_HUMAN
θ value	9.87957e-23 (rank : 82)	NC score	0.492142 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	241	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

RADI_HUMAN
θ value	1.6852e-22 (rank : 83)	NC score	0.477881 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	741	Shared Neighborhood Hits	55
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	1.6852e-22 (rank : 84)	NC score	0.475340 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	773	Shared Neighborhood Hits	56
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MOES_MOUSE
θ value	3.75424e-22 (rank : 85)	NC score	0.443439 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	923	Shared Neighborhood Hits	55
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
θ value	4.9032e-22 (rank : 86)	NC score	0.448547 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	892	Shared Neighborhood Hits	55
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

EZRI_HUMAN
θ value	6.40375e-22 (rank : 87)	NC score	0.489298 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	663	Shared Neighborhood Hits	55
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	8.36355e-22 (rank : 88)	NC score	0.486109 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FRM4B_HUMAN
θ value	8.36355e-22 (rank : 89)	NC score	0.546899 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FARP2_HUMAN
θ value	1.42661e-21 (rank : 90)	NC score	0.476238 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	47
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MYLIP_HUMAN
θ value	5.42112e-21 (rank : 91)	NC score	0.553777 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRM4A_HUMAN
θ value	2.27762e-19 (rank : 92)	NC score	0.538186 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
θ value	3.88503e-19 (rank : 93)	NC score	0.536994 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	108	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRMD6_MOUSE
θ value	7.09661e-13 (rank : 94)	NC score	0.495264 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
θ value	3.52202e-12 (rank : 95)	NC score	0.489018 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD1_HUMAN
θ value	7.34386e-10 (rank : 96)	NC score	0.486838 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

TLN1_HUMAN
θ value	0.000602161 (rank : 97)	NC score	0.248837 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	218	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	0.000602161 (rank : 98)	NC score	0.246549 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

MYO7A_HUMAN
θ value	0.00509761 (rank : 99)	NC score	0.041938 (rank : 177)
Query Neighborhood Hits	163	Target Neighborhood Hits	209	Shared Neighborhood Hits	29
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	0.00509761 (rank : 100)	NC score	0.042173 (rank : 176)
Query Neighborhood Hits	163	Target Neighborhood Hits	235	Shared Neighborhood Hits	27
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

TLN2_MOUSE
θ value	0.0961366 (rank : 101)	NC score	0.241628 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

SFPQ_MOUSE
θ value	0.279714 (rank : 102)	NC score	0.005323 (rank : 208)
Query Neighborhood Hits	163	Target Neighborhood Hits	958	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CSKI1_MOUSE
θ value	0.365318 (rank : 103)	NC score	0.006935 (rank : 204)
Query Neighborhood Hits	163	Target Neighborhood Hits	1031	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PYGO1_MOUSE
θ value	0.47712 (rank : 104)	NC score	0.020716 (rank : 185)
Query Neighborhood Hits	163	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D0P5	Gene names	Pygo1
Domain Architecture
Description	Pygopus homolog 1.

TLN2_HUMAN
θ value	0.47712 (rank : 105)	NC score	0.237136 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

DUS2_MOUSE
θ value	0.62314 (rank : 106)	NC score	0.036528 (rank : 178)
Query Neighborhood Hits	163	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

MPIP3_HUMAN
θ value	0.813845 (rank : 107)	NC score	0.011071 (rank : 195)
Query Neighborhood Hits	163	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

CC14B_HUMAN
θ value	1.06291 (rank : 108)	NC score	0.124305 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS13_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.033341 (rank : 179)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

DUS2_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.020697 (rank : 186)
Query Neighborhood Hits	163	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

CSKI1_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.003069 (rank : 212)
Query Neighborhood Hits	163	Target Neighborhood Hits	997	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TRAK1_HUMAN
θ value	1.38821 (rank : 112)	NC score	0.015701 (rank : 190)
Query Neighborhood Hits	163	Target Neighborhood Hits	660	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

UBQL3_MOUSE
θ value	1.38821 (rank : 113)	NC score	0.007288 (rank : 203)
Query Neighborhood Hits	163	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

AL2SA_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.025944 (rank : 181)
Query Neighborhood Hits	163	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

CC14A_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.109905 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	133	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
θ value	1.81305 (rank : 116)	NC score	0.112638 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

INSM1_MOUSE
θ value	1.81305 (rank : 117)	NC score	-0.003415 (rank : 221)
Query Neighborhood Hits	163	Target Neighborhood Hits	678	Shared Neighborhood Hits	5
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

CC14B_MOUSE
θ value	2.36792 (rank : 118)	NC score	0.122154 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

GMEB2_HUMAN
θ value	2.36792 (rank : 119)	NC score	0.007682 (rank : 202)
Query Neighborhood Hits	163	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

PCLO_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.010078 (rank : 196)
Query Neighborhood Hits	163	Target Neighborhood Hits	2046	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ANC5_MOUSE
θ value	3.0926 (rank : 121)	NC score	0.008605 (rank : 200)
Query Neighborhood Hits	163	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTZ4, Q3TGA7, Q80UJ6, Q80W43, Q8BWW7, Q8C0F7, Q9CRX0, Q9CSL1, Q9JJB8	Gene names	Anapc5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

DUS13_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.027768 (rank : 180)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

MA2B2_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.005943 (rank : 206)
Query Neighborhood Hits	163	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2E5, Q66MP2, Q86T67	Gene names	MAN2B2, KIAA0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

NRK_HUMAN
θ value	3.0926 (rank : 124)	NC score	-0.007192 (rank : 226)
Query Neighborhood Hits	163	Target Neighborhood Hits	931	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

SDCG8_MOUSE
θ value	3.0926 (rank : 125)	NC score	0.019720 (rank : 187)
Query Neighborhood Hits	163	Target Neighborhood Hits	886	Shared Neighborhood Hits	16
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SFPQ_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.002278 (rank : 214)
Query Neighborhood Hits	163	Target Neighborhood Hits	986	Shared Neighborhood Hits	15
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

DAXX_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.013666 (rank : 192)
Query Neighborhood Hits	163	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DUS11_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.024702 (rank : 183)
Query Neighborhood Hits	163	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

DUS1_HUMAN
θ value	4.03905 (rank : 129)	NC score	0.021970 (rank : 184)
Query Neighborhood Hits	163	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

PYGO1_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.018353 (rank : 188)
Query Neighborhood Hits	163	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

SRRM2_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.016067 (rank : 189)
Query Neighborhood Hits	163	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TAOK3_MOUSE
θ value	4.03905 (rank : 132)	NC score	-0.004544 (rank : 224)
Query Neighborhood Hits	163	Target Neighborhood Hits	1458	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

ZFP14_HUMAN
θ value	4.03905 (rank : 133)	NC score	-0.007839 (rank : 227)
Query Neighborhood Hits	163	Target Neighborhood Hits	743	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCL3	Gene names	ZFP14, KIAA1559
Domain Architecture
Description	Zinc finger protein 14 homolog (Zfp-14).

DGAT1_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.009391 (rank : 197)
Query Neighborhood Hits	163	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2A7, Q9D7Q5	Gene names	Dgat1, Dgat
Domain Architecture
Description	Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Diglyceride acyltransferase).

FMO2_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.002371 (rank : 213)
Query Neighborhood Hits	163	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

SREC2_HUMAN
θ value	5.27518 (rank : 136)	NC score	-0.003556 (rank : 222)
Query Neighborhood Hits	163	Target Neighborhood Hits	645	Shared Neighborhood Hits	7
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TP4A1_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.097463 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.097463 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TXND2_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.008995 (rank : 199)
Query Neighborhood Hits	163	Target Neighborhood Hits	828	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CCD41_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.011723 (rank : 194)
Query Neighborhood Hits	163	Target Neighborhood Hits	1399	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CJ030_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.006102 (rank : 205)
Query Neighborhood Hits	163	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N7W2, Q5SYY7, Q5SYY8, Q5SYY9, Q8N5T7	Gene names	C10orf30
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf30.

CKAP5_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.008202 (rank : 201)
Query Neighborhood Hits	163	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

DCC_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.082709 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	896	Shared Neighborhood Hits	30
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DDX20_HUMAN
θ value	6.88961 (rank : 144)	NC score	-0.000829 (rank : 220)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DOCK3_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.003519 (rank : 211)
Query Neighborhood Hits	163	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.004102 (rank : 209)
Query Neighborhood Hits	163	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DUS10_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.012693 (rank : 193)
Query Neighborhood Hits	163	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS19_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.014939 (rank : 191)
Query Neighborhood Hits	163	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

PLXB2_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.000382 (rank : 216)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

TP4A2_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.081139 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	6.88961 (rank : 151)	NC score	0.081139 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

UBP42_HUMAN
θ value	6.88961 (rank : 152)	NC score	-0.000163 (rank : 217)
Query Neighborhood Hits	163	Target Neighborhood Hits	445	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

ZO2_HUMAN
θ value	6.88961 (rank : 153)	NC score	0.024708 (rank : 182)
Query Neighborhood Hits	163	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

CSPG3_MOUSE
θ value	8.99809 (rank : 154)	NC score	-0.003880 (rank : 223)
Query Neighborhood Hits	163	Target Neighborhood Hits	657	Shared Neighborhood Hits	7
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DUS19_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.009032 (rank : 198)
Query Neighborhood Hits	163	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

FOXO1_HUMAN
θ value	8.99809 (rank : 156)	NC score	-0.000445 (rank : 219)
Query Neighborhood Hits	163	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

GLI3_MOUSE
θ value	8.99809 (rank : 157)	NC score	-0.007973 (rank : 228)
Query Neighborhood Hits	163	Target Neighborhood Hits	807	Shared Neighborhood Hits	5
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

KRIT1_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.057392 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PEX6_MOUSE
θ value	8.99809 (rank : 159)	NC score	-0.000412 (rank : 218)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

RAPH1_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.005670 (rank : 207)
Query Neighborhood Hits	163	Target Neighborhood Hits	593	Shared Neighborhood Hits	20
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

T22D4_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.003811 (rank : 210)
Query Neighborhood Hits	163	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TAOK3_HUMAN
θ value	8.99809 (rank : 162)	NC score	-0.005122 (rank : 225)
Query Neighborhood Hits	163	Target Neighborhood Hits	1494	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

VMDL3_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.002152 (rank : 215)
Query Neighborhood Hits	163	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1M1, Q8N356, Q8NFT9, Q9BR80	Gene names	VMD2L3
Domain Architecture
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

CA106_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.068393 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.067551 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CDKN3_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.063793 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

CNTN1_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.054284 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN1_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.055391 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	422	Shared Neighborhood Hits	13
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN2_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.058290 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.058022 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	450	Shared Neighborhood Hits	13
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN3_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.051332 (rank : 173)
Query Neighborhood Hits	163	Target Neighborhood Hits	455	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN3_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.053425 (rank : 167)
Query Neighborhood Hits	163	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN5_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.059973 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	446	Shared Neighborhood Hits	16
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN5_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.058603 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	434	Shared Neighborhood Hits	15
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CNTN6_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.052596 (rank : 169)
Query Neighborhood Hits	163	Target Neighborhood Hits	422	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CO7A1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.057753 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	807	Shared Neighborhood Hits	23
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COCA1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.073109 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	458	Shared Neighborhood Hits	23
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.074540 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	467	Shared Neighborhood Hits	21
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.054438 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	427	Shared Neighborhood Hits	15
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.061314 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	402	Shared Neighborhood Hits	17
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DCC_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.085176 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	583	Shared Neighborhood Hits	25
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DSCAM_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.062200 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	524	Shared Neighborhood Hits	19
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.062311 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	589	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

DUS23_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.219318 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

DUS23_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.228573 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

FINC_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.112222 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	302	Shared Neighborhood Hits	21
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.111420 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	309	Shared Neighborhood Hits	21
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FNDC3_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.101533 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.094987 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ITB4_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.065572 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	458	Shared Neighborhood Hits	19
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KRIT1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.057274 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

L1CAM_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.062737 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	457	Shared Neighborhood Hits	16
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.063516 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LIFR_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.051757 (rank : 172)
Query Neighborhood Hits	163	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

MAMC1_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.055269 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.056263 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC2_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.070396 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.073378 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MDGA1_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.058333 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	358	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MYOM1_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.053477 (rank : 166)
Query Neighborhood Hits	163	Target Neighborhood Hits	405	Shared Neighborhood Hits	14
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

MYOM1_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.056825 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	415	Shared Neighborhood Hits	16
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

MYOM2_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.050043 (rank : 175)
Query Neighborhood Hits	163	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

NEO1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.080334 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	530	Shared Neighborhood Hits	22
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.082753 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	523	Shared Neighborhood Hits	22
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NFASC_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.054816 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	497	Shared Neighborhood Hits	18
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NFASC_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.052472 (rank : 170)
Query Neighborhood Hits	163	Target Neighborhood Hits	475	Shared Neighborhood Hits	18
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

NRCAM_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.060296 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	439	Shared Neighborhood Hits	15
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.062410 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	432	Shared Neighborhood Hits	17
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PTEN_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.081601 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.081600 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	73	Shared Neighborhood Hits	40
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

PUNC_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.052731 (rank : 168)
Query Neighborhood Hits	163	Target Neighborhood Hits	449	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RES18_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.054627 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

ROBO3_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.051945 (rank : 171)
Query Neighborhood Hits	163	Target Neighborhood Hits	524	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

SDK1_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.068262 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	511	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.069446 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	495	Shared Neighborhood Hits	22
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.069213 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	495	Shared Neighborhood Hits	21
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.071955 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	480	Shared Neighborhood Hits	19
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

TARSH_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.058657 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	768	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TENA_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.055713 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	631	Shared Neighborhood Hits	22
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.050821 (rank : 174)
Query Neighborhood Hits	163	Target Neighborhood Hits	596	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.066676 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	453	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.077913 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.065527 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	526	Shared Neighborhood Hits	20
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.065577 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	531	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TP4A3_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.077825 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.069901 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

USH2A_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.070916 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.067830 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	626	Shared Neighborhood Hits	23
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

Hits sorted by NC score

PTN14_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
NC score	0.998574 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	142	Shared Neighborhood Hits	120
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN21_HUMAN
NC score	0.993803 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	107
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
NC score	0.992940 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	155	Shared Neighborhood Hits	104
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN3_HUMAN
NC score	0.926253 (rank : 5)	θ value	1.51013e-55 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	258	Shared Neighborhood Hits	113
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
NC score	0.916968 (rank : 6)	θ value	4.54686e-52 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	303	Shared Neighborhood Hits	113
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN1_MOUSE
NC score	0.816625 (rank : 7)	θ value	6.37413e-38 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN1_HUMAN
NC score	0.816209 (rank : 8)	θ value	2.19075e-38 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	84	Shared Neighborhood Hits	66
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN2_MOUSE
NC score	0.814854 (rank : 9)	θ value	1.85459e-37 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN13_MOUSE
NC score	0.814564 (rank : 10)	θ value	3.48949e-44 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	426	Shared Neighborhood Hits	116
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN2_HUMAN
NC score	0.813852 (rank : 11)	θ value	9.20422e-37 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	92	Shared Neighborhood Hits	63
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN18_HUMAN
NC score	0.813641 (rank : 12)	θ value	4.568e-36 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
NC score	0.809580 (rank : 13)	θ value	1.6247e-33 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	68
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN7_MOUSE
NC score	0.808414 (rank : 14)	θ value	2.12192e-33 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN7_HUMAN
NC score	0.807658 (rank : 15)	θ value	1.79631e-32 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN22_HUMAN
NC score	0.805465 (rank : 16)	θ value	1.20211e-36 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN13_HUMAN
NC score	0.804429 (rank : 17)	θ value	1.91475e-42 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	471	Shared Neighborhood Hits	112
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN9_MOUSE
NC score	0.802888 (rank : 18)	θ value	1.3722e-40 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	78	Shared Neighborhood Hits	65
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_HUMAN
NC score	0.802868 (rank : 19)	θ value	1.05066e-40 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN12_HUMAN
NC score	0.801900 (rank : 20)	θ value	8.06329e-33 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
NC score	0.801147 (rank : 21)	θ value	5.22648e-32 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	123	Shared Neighborhood Hits	67
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN22_MOUSE
NC score	0.798316 (rank : 22)	θ value	6.59618e-35 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	179	Shared Neighborhood Hits	68
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN5_MOUSE
NC score	0.797850 (rank : 23)	θ value	4.57862e-28 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.797364 (rank : 24)	θ value	5.97985e-28 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

CD45_MOUSE
NC score	0.796206 (rank : 25)	θ value	9.50281e-42 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	178	Shared Neighborhood Hits	68
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRO_HUMAN
NC score	0.795503 (rank : 26)	θ value	3.06405e-32 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	139	Shared Neighborhood Hits	74
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_MOUSE
NC score	0.794059 (rank : 27)	θ value	8.3442e-30 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRR_HUMAN
NC score	0.793259 (rank : 28)	θ value	9.2256e-29 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRA_HUMAN
NC score	0.789994 (rank : 29)	θ value	7.04741e-37 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	101	Shared Neighborhood Hits	67
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

CD45_HUMAN
NC score	0.789644 (rank : 30)	θ value	8.04462e-41 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	243	Shared Neighborhood Hits	67
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRA_MOUSE
NC score	0.789610 (rank : 31)	θ value	1.57e-36 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_HUMAN
NC score	0.788899 (rank : 32)	θ value	2.96089e-35 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
NC score	0.788335 (rank : 33)	θ value	5.584e-34 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPR2_HUMAN
NC score	0.788106 (rank : 34)	θ value	1.02001e-27 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
NC score	0.787238 (rank : 35)	θ value	4.14116e-29 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRN_HUMAN
NC score	0.784457 (rank : 36)	θ value	1.33217e-27 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
NC score	0.781319 (rank : 37)	θ value	5.97985e-28 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	68
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRJ_MOUSE
NC score	0.772728 (rank : 38)	θ value	8.61488e-35 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	188	Shared Neighborhood Hits	73
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN6_HUMAN
NC score	0.770632 (rank : 39)	θ value	3.48949e-44 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	234	Shared Neighborhood Hits	69
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTPRJ_HUMAN
NC score	0.769050 (rank : 40)	θ value	5.0505e-35 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	207	Shared Neighborhood Hits	73
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN6_MOUSE
NC score	0.768699 (rank : 41)	θ value	4.122e-45 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRV_MOUSE
NC score	0.765507 (rank : 42)	θ value	1.46948e-34 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	179	Shared Neighborhood Hits	66
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN11_HUMAN
NC score	0.747171 (rank : 43)	θ value	2.86122e-38 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.747107 (rank : 44)	θ value	3.73686e-38 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTPRB_HUMAN
NC score	0.743373 (rank : 45)	θ value	1.08726e-37 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	242	Shared Neighborhood Hits	70
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRK_HUMAN
NC score	0.734842 (rank : 46)	θ value	5.0505e-35 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
NC score	0.733378 (rank : 47)	θ value	2.96089e-35 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	223	Shared Neighborhood Hits	68
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRT_MOUSE
NC score	0.728166 (rank : 48)	θ value	2.12192e-33 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.728163 (rank : 49)	θ value	2.12192e-33 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	217	Shared Neighborhood Hits	65
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRU_HUMAN
NC score	0.720022 (rank : 50)	θ value	3.74554e-30 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	237	Shared Neighborhood Hits	66
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_MOUSE
NC score	0.716920 (rank : 51)	θ value	8.06329e-33 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	238	Shared Neighborhood Hits	67
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.714989 (rank : 52)	θ value	3.06405e-32 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	244	Shared Neighborhood Hits	67
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRZ_HUMAN
NC score	0.714896 (rank : 53)	θ value	7.04741e-37 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	255	Shared Neighborhood Hits	65
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_HUMAN
NC score	0.713428 (rank : 54)	θ value	2.26708e-35 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	231	Shared Neighborhood Hits	69
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
NC score	0.711041 (rank : 55)	θ value	2.96089e-35 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	260	Shared Neighborhood Hits	70
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTN23_HUMAN
NC score	0.697356 (rank : 56)	θ value	9.2256e-29 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	646	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
NC score	0.695384 (rank : 57)	θ value	1.2049e-28 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	726	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

E41LA_HUMAN
NC score	0.604937 (rank : 58)	θ value	1.85889e-29 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.604834 (rank : 59)	θ value	7.80994e-28 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	85	Shared Neighborhood Hits	49
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LB_MOUSE
NC score	0.603658 (rank : 60)	θ value	1.57365e-28 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41L5_HUMAN
NC score	0.602676 (rank : 61)	θ value	7.54701e-31 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

FRMD5_MOUSE
NC score	0.602451 (rank : 62)	θ value	8.63488e-27 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
NC score	0.601457 (rank : 63)	θ value	6.61148e-27 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LB_HUMAN
NC score	0.596979 (rank : 64)	θ value	7.06379e-29 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41L3_HUMAN
NC score	0.593210 (rank : 65)	θ value	1.2049e-28 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L1_MOUSE
NC score	0.590887 (rank : 66)	θ value	6.38894e-30 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_HUMAN
NC score	0.590655 (rank : 67)	θ value	2.68423e-28 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L1_HUMAN
NC score	0.588047 (rank : 68)	θ value	2.86786e-30 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_MOUSE
NC score	0.586777 (rank : 69)	θ value	9.54697e-26 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L3_MOUSE
NC score	0.583675 (rank : 70)	θ value	7.06379e-29 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
NC score	0.582837 (rank : 71)	θ value	1.6813e-30 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	287	Shared Neighborhood Hits	51
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

PTPRS_HUMAN
NC score	0.577840 (rank : 72)	θ value	4.2656e-42 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	472	Shared Neighborhood Hits	71
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

MYLIP_MOUSE
NC score	0.568921 (rank : 73)	θ value	5.79196e-23 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

E41L2_MOUSE
NC score	0.567816 (rank : 74)	θ value	4.89182e-30 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	459	Shared Neighborhood Hits	51
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

PTPRD_HUMAN
NC score	0.567218 (rank : 75)	θ value	1.2411e-41 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	485	Shared Neighborhood Hits	74
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.563198 (rank : 76)	θ value	7.52953e-39 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	489	Shared Neighborhood Hits	71
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.557496 (rank : 77)	θ value	1.28434e-38 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

MYLIP_HUMAN
NC score	0.553777 (rank : 78)	θ value	5.42112e-21 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRM4B_MOUSE
NC score	0.548072 (rank : 79)	θ value	7.56453e-23 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4B_HUMAN
NC score	0.546899 (rank : 80)	θ value	8.36355e-22 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4A_HUMAN
NC score	0.538186 (rank : 81)	θ value	2.27762e-19 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
NC score	0.536994 (rank : 82)	θ value	3.88503e-19 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	108	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

MERL_MOUSE
NC score	0.520275 (rank : 83)	θ value	1.5242e-23 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	524	Shared Neighborhood Hits	55
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.519867 (rank : 84)	θ value	1.16704e-23 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	532	Shared Neighborhood Hits	55
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FRMD6_MOUSE
NC score	0.495264 (rank : 85)	θ value	7.09661e-13 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FARP1_HUMAN
NC score	0.492142 (rank : 86)	θ value	9.87957e-23 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	241	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

EZRI_HUMAN
NC score	0.489298 (rank : 87)	θ value	6.40375e-22 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	663	Shared Neighborhood Hits	55
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FRMD6_HUMAN
NC score	0.489018 (rank : 88)	θ value	3.52202e-12 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD1_HUMAN
NC score	0.486838 (rank : 89)	θ value	7.34386e-10 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

EZRI_MOUSE
NC score	0.486109 (rank : 90)	θ value	8.36355e-22 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
NC score	0.477881 (rank : 91)	θ value	1.6852e-22 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	741	Shared Neighborhood Hits	55
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

FARP2_HUMAN
NC score	0.476238 (rank : 92)	θ value	1.42661e-21 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	47
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

RADI_MOUSE
NC score	0.475340 (rank : 93)	θ value	1.6852e-22 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	773	Shared Neighborhood Hits	56
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

FARP2_MOUSE
NC score	0.473060 (rank : 94)	θ value	2.35151e-24 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MOES_HUMAN
NC score	0.448547 (rank : 95)	θ value	4.9032e-22 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	892	Shared Neighborhood Hits	55
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
NC score	0.443439 (rank : 96)	θ value	3.75424e-22 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	923	Shared Neighborhood Hits	55
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

TLN1_HUMAN
NC score	0.248837 (rank : 97)	θ value	0.000602161 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	218	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.246549 (rank : 98)	θ value	0.000602161 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.241628 (rank : 99)	θ value	0.0961366 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.237136 (rank : 100)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

DUS23_MOUSE
NC score	0.228573 (rank : 101)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

DUS23_HUMAN
NC score	0.219318 (rank : 102)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	163	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

CC14B_HUMAN
NC score	0.124305 (rank : 103)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14B_MOUSE
NC score	0.122154 (rank : 104)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14A_MOUSE
NC score	0.112638 (rank : 105)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

FINC_HUMAN
NC score	0.112222 (rank : 106)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	163	Target Neighborhood Hits	302	Shared Neighborhood Hits	21
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.111420 (rank : 107)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	163	Target Neighborhood Hits	309	Shared Neighborhood Hits	21
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

CC14A_HUMAN
NC score	0.109905 (rank : 108)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	133	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

FNDC3_HUMAN
NC score	0.101533 (rank : 109)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	163	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

TP4A1_HUMAN
NC score	0.097463 (rank : 110)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.097463 (rank : 111)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

FNDC3_MOUSE
NC score	0.094987 (rank : 112)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	163	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

DCC_HUMAN
NC score	0.085176 (rank : 113)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	163	Target Neighborhood Hits	583	Shared Neighborhood Hits	25
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

NEO1_MOUSE
NC score	0.082753 (rank : 114)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	163	Target Neighborhood Hits	523	Shared Neighborhood Hits	22
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

DCC_MOUSE
NC score	0.082709 (rank : 115)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	896	Shared Neighborhood Hits	30
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

PTEN_HUMAN
NC score	0.081601 (rank : 116)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.081600 (rank : 117)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	163	Target Neighborhood Hits	73	Shared Neighborhood Hits	40
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

TP4A2_HUMAN
NC score	0.081139 (rank : 118)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.081139 (rank : 119)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

NEO1_HUMAN
NC score	0.080334 (rank : 120)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	163	Target Neighborhood Hits	530	Shared Neighborhood Hits	22
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

TENN_MOUSE
NC score	0.077913 (rank : 121)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	163	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TP4A3_HUMAN
NC score	0.077825 (rank : 122)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	163	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

COCA1_MOUSE
NC score	0.074540 (rank : 123)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	163	Target Neighborhood Hits	467	Shared Neighborhood Hits	21
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MAMC2_MOUSE
NC score	0.073378 (rank : 124)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	163	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

COCA1_HUMAN
NC score	0.073109 (rank : 125)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	163	Target Neighborhood Hits	458	Shared Neighborhood Hits	23
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

SDK2_MOUSE
NC score	0.071955 (rank : 126)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	163	Target Neighborhood Hits	480	Shared Neighborhood Hits	19
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

USH2A_HUMAN
NC score	0.070916 (rank : 127)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	163	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

MAMC2_HUMAN
NC score	0.070396 (rank : 128)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	163	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

TP4A3_MOUSE
NC score	0.069901 (rank : 129)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	163	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

SDK1_MOUSE
NC score	0.069446 (rank : 130)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	163	Target Neighborhood Hits	495	Shared Neighborhood Hits	22
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
NC score	0.069213 (rank : 131)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	163	Target Neighborhood Hits	495	Shared Neighborhood Hits	21
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

CA106_HUMAN
NC score	0.068393 (rank : 132)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

SDK1_HUMAN
NC score	0.068262 (rank : 133)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	163	Target Neighborhood Hits	511	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

USH2A_MOUSE
NC score	0.067830 (rank : 134)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	163	Target Neighborhood Hits	626	Shared Neighborhood Hits	23
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

CA106_MOUSE
NC score	0.067551 (rank : 135)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

TENN_HUMAN
NC score	0.066676 (rank : 136)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	163	Target Neighborhood Hits	453	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_MOUSE
NC score	0.065577 (rank : 137)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	163	Target Neighborhood Hits	531	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

ITB4_HUMAN
NC score	0.065572 (rank : 138)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	163	Target Neighborhood Hits	458	Shared Neighborhood Hits	19
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

TENR_HUMAN
NC score	0.065527 (rank : 139)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	163	Target Neighborhood Hits	526	Shared Neighborhood Hits	20
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

CDKN3_HUMAN
NC score	0.063793 (rank : 140)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	163	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

L1CAM_MOUSE
NC score	0.063516 (rank : 141)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	163	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_HUMAN
NC score	0.062737 (rank : 142)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	163	Target Neighborhood Hits	457	Shared Neighborhood Hits	16
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

NRCAM_MOUSE
NC score	0.062410 (rank : 143)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	163	Target Neighborhood Hits	432	Shared Neighborhood Hits	17
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

DSCL1_HUMAN
NC score	0.062311 (rank : 144)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	163	Target Neighborhood Hits	589	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

DSCAM_HUMAN
NC score	0.062200 (rank : 145)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	163	Target Neighborhood Hits	524	Shared Neighborhood Hits	19
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

COEA1_MOUSE
NC score	0.061314 (rank : 146)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	163	Target Neighborhood Hits	402	Shared Neighborhood Hits	17
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

NRCAM_HUMAN
NC score	0.060296 (rank : 147)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	163	Target Neighborhood Hits	439	Shared Neighborhood Hits	15
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

CNTN5_HUMAN
NC score	0.059973 (rank : 148)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	163	Target Neighborhood Hits	446	Shared Neighborhood Hits	16
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

TARSH_HUMAN
NC score	0.058657 (rank : 149)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	163	Target Neighborhood Hits	768	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CNTN5_MOUSE
NC score	0.058603 (rank : 150)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	163	Target Neighborhood Hits	434	Shared Neighborhood Hits	15
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

MDGA1_HUMAN
NC score	0.058333 (rank : 151)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	163	Target Neighborhood Hits	358	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

CNTN2_HUMAN
NC score	0.058290 (rank : 152)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	163	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
NC score	0.058022 (rank : 153)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	163	Target Neighborhood Hits	450	Shared Neighborhood Hits	13
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CO7A1_HUMAN
NC score	0.057753 (rank : 154)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	163	Target Neighborhood Hits	807	Shared Neighborhood Hits	23
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

KRIT1_MOUSE
NC score	0.057392 (rank : 155)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

KRIT1_HUMAN
NC score	0.057274 (rank : 156)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	163	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

MYOM1_MOUSE
NC score	0.056825 (rank : 157)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	163	Target Neighborhood Hits	415	Shared Neighborhood Hits	16
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

MAMC1_MOUSE
NC score	0.056263 (rank : 158)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

TENA_HUMAN
NC score	0.055713 (rank : 159)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	163	Target Neighborhood Hits	631	Shared Neighborhood Hits	22
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

CNTN1_MOUSE
NC score	0.055391 (rank : 160)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	163	Target Neighborhood Hits	422	Shared Neighborhood Hits	13
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

MAMC1_HUMAN
NC score	0.055269 (rank : 161)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

NFASC_HUMAN
NC score	0.054816 (rank : 162)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	163	Target Neighborhood Hits	497	Shared Neighborhood Hits	18
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

RES18_MOUSE
NC score	0.054627 (rank : 163)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	163	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

COEA1_HUMAN
NC score	0.054438 (rank : 164)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	163	Target Neighborhood Hits	427	Shared Neighborhood Hits	15
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CNTN1_HUMAN
NC score	0.054284 (rank : 165)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	163	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

MYOM1_HUMAN
NC score	0.053477 (rank : 166)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	163	Target Neighborhood Hits	405	Shared Neighborhood Hits	14
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

CNTN3_MOUSE
NC score	0.053425 (rank : 167)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	163	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

PUNC_HUMAN
NC score	0.052731 (rank : 168)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	163	Target Neighborhood Hits	449	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

CNTN6_HUMAN
NC score	0.052596 (rank : 169)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	163	Target Neighborhood Hits	422	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

NFASC_MOUSE
NC score	0.052472 (rank : 170)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	163	Target Neighborhood Hits	475	Shared Neighborhood Hits	18
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

ROBO3_MOUSE
NC score	0.051945 (rank : 171)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	163	Target Neighborhood Hits	524	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

LIFR_MOUSE
NC score	0.051757 (rank : 172)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	163	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

CNTN3_HUMAN
NC score	0.051332 (rank : 173)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	163	Target Neighborhood Hits	455	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

TENA_MOUSE
NC score	0.050821 (rank : 174)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	163	Target Neighborhood Hits	596	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

MYOM2_HUMAN
NC score	0.050043 (rank : 175)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	163	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

MYO7A_MOUSE
NC score	0.042173 (rank : 176)	θ value	0.00509761 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	235	Shared Neighborhood Hits	27
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.041938 (rank : 177)	θ value	0.00509761 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	209	Shared Neighborhood Hits	29
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

DUS2_MOUSE
NC score	0.036528 (rank : 178)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS13_HUMAN
NC score	0.033341 (rank : 179)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

DUS13_MOUSE
NC score	0.027768 (rank : 180)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

AL2SA_HUMAN
NC score	0.025944 (rank : 181)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

ZO2_HUMAN
NC score	0.024708 (rank : 182)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DUS11_HUMAN
NC score	0.024702 (rank : 183)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

DUS1_HUMAN
NC score	0.021970 (rank : 184)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

PYGO1_MOUSE
NC score	0.020716 (rank : 185)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D0P5	Gene names	Pygo1
Domain Architecture
Description	Pygopus homolog 1.

DUS2_HUMAN
NC score	0.020697 (rank : 186)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

SDCG8_MOUSE
NC score	0.019720 (rank : 187)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	886	Shared Neighborhood Hits	16
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

PYGO1_HUMAN
NC score	0.018353 (rank : 188)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

SRRM2_HUMAN
NC score	0.016067 (rank : 189)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRAK1_HUMAN
NC score	0.015701 (rank : 190)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	660	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

DUS19_MOUSE
NC score	0.014939 (rank : 191)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DAXX_MOUSE
NC score	0.013666 (rank : 192)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DUS10_MOUSE
NC score	0.012693 (rank : 193)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

CCD41_MOUSE
NC score	0.011723 (rank : 194)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	1399	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MPIP3_HUMAN
NC score	0.011071 (rank : 195)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

PCLO_HUMAN
NC score	0.010078 (rank : 196)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	2046	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DGAT1_MOUSE
NC score	0.009391 (rank : 197)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2A7, Q9D7Q5	Gene names	Dgat1, Dgat
Domain Architecture
Description	Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Diglyceride acyltransferase).

DUS19_HUMAN
NC score	0.009032 (rank : 198)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

TXND2_MOUSE
NC score	0.008995 (rank : 199)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	828	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ANC5_MOUSE
NC score	0.008605 (rank : 200)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTZ4, Q3TGA7, Q80UJ6, Q80W43, Q8BWW7, Q8C0F7, Q9CRX0, Q9CSL1, Q9JJB8	Gene names	Anapc5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

CKAP5_HUMAN
NC score	0.008202 (rank : 201)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

GMEB2_HUMAN
NC score	0.007682 (rank : 202)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

UBQL3_MOUSE
NC score	0.007288 (rank : 203)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

CSKI1_MOUSE
NC score	0.006935 (rank : 204)	θ value	0.365318 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	1031	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CJ030_HUMAN
NC score	0.006102 (rank : 205)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N7W2, Q5SYY7, Q5SYY8, Q5SYY9, Q8N5T7	Gene names	C10orf30
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf30.

MA2B2_HUMAN
NC score	0.005943 (rank : 206)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2E5, Q66MP2, Q86T67	Gene names	MAN2B2, KIAA0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

RAPH1_HUMAN
NC score	0.005670 (rank : 207)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	593	Shared Neighborhood Hits	20
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SFPQ_MOUSE
NC score	0.005323 (rank : 208)	θ value	0.279714 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	958	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

DOCK3_MOUSE
NC score	0.004102 (rank : 209)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

T22D4_HUMAN
NC score	0.003811 (rank : 210)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

DOCK3_HUMAN
NC score	0.003519 (rank : 211)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

CSKI1_HUMAN
NC score	0.003069 (rank : 212)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	997	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FMO2_HUMAN
NC score	0.002371 (rank : 213)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

SFPQ_HUMAN
NC score	0.002278 (rank : 214)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	986	Shared Neighborhood Hits	15
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

VMDL3_HUMAN
NC score	0.002152 (rank : 215)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1M1, Q8N356, Q8NFT9, Q9BR80	Gene names	VMD2L3
Domain Architecture
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

PLXB2_HUMAN
NC score	0.000382 (rank : 216)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

UBP42_HUMAN
NC score	-0.000163 (rank : 217)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	445	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

PEX6_MOUSE
NC score	-0.000412 (rank : 218)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

FOXO1_HUMAN
NC score	-0.000445 (rank : 219)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

DDX20_HUMAN
NC score	-0.000829 (rank : 220)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

INSM1_MOUSE
NC score	-0.003415 (rank : 221)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	678	Shared Neighborhood Hits	5
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

SREC2_HUMAN
NC score	-0.003556 (rank : 222)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	645	Shared Neighborhood Hits	7
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

CSPG3_MOUSE
NC score	-0.003880 (rank : 223)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	657	Shared Neighborhood Hits	7
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TAOK3_MOUSE
NC score	-0.004544 (rank : 224)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	1458	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

TAOK3_HUMAN
NC score	-0.005122 (rank : 225)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	1494	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

NRK_HUMAN
NC score	-0.007192 (rank : 226)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	931	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

ZFP14_HUMAN
NC score	-0.007839 (rank : 227)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	743	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCL3	Gene names	ZFP14, KIAA1559
Domain Architecture
Description	Zinc finger protein 14 homolog (Zfp-14).

GLI3_MOUSE
NC score	-0.007973 (rank : 228)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	807	Shared Neighborhood Hits	5
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.