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Network neighborhood for query Sequence : PTEN_MOUSE

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PTEN_MOUSE
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTEN_HUMAN
θ value	0 (rank : 1)	NC score	0.999924 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

TPTE2_HUMAN
θ value	7.24236e-58 (rank : 3)	NC score	0.872031 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

TPTE_HUMAN
θ value	4.11246e-53 (rank : 4)	NC score	0.871549 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

TENS1_HUMAN
θ value	9.52487e-34 (rank : 5)	NC score	0.622598 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	400	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

GAK_MOUSE
θ value	3.28125e-26 (rank : 6)	NC score	0.254406 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	964	Shared Neighborhood Hits	11
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GAK_HUMAN
θ value	7.30988e-26 (rank : 7)	NC score	0.248420 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	1028	Shared Neighborhood Hits	9
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

AUXI_HUMAN
θ value	6.84181e-24 (rank : 8)	NC score	0.686280 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

AUXI_MOUSE
θ value	5.79196e-23 (rank : 9)	NC score	0.682180 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

TP4A1_HUMAN
θ value	0.000461057 (rank : 10)	NC score	0.269507 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	68	Shared Neighborhood Hits	39
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	0.000461057 (rank : 11)	NC score	0.269507 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	68	Shared Neighborhood Hits	39
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

CC14A_MOUSE
θ value	0.000602161 (rank : 12)	NC score	0.247641 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	117	Shared Neighborhood Hits	54
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

TP4A3_MOUSE
θ value	0.000602161 (rank : 13)	NC score	0.277116 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

TP4A2_HUMAN
θ value	0.000786445 (rank : 14)	NC score	0.261978 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	0.000786445 (rank : 15)	NC score	0.261978 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

PTN22_MOUSE
θ value	0.00102713 (rank : 16)	NC score	0.134019 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	179	Shared Neighborhood Hits	34
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

CC14B_HUMAN
θ value	0.00134147 (rank : 17)	NC score	0.259214 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14A_HUMAN
θ value	0.00228821 (rank : 18)	NC score	0.240659 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

TP4A3_HUMAN
θ value	0.00228821 (rank : 19)	NC score	0.267112 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	62	Shared Neighborhood Hits	40
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

PTPRD_MOUSE
θ value	0.00390308 (rank : 20)	NC score	0.103463 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CC14B_MOUSE
θ value	0.0252991 (rank : 21)	NC score	0.232395 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PTPRA_MOUSE
θ value	0.0330416 (rank : 22)	NC score	0.138140 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRA_HUMAN
θ value	0.0431538 (rank : 23)	NC score	0.136534 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRF_HUMAN
θ value	0.0431538 (rank : 24)	NC score	0.098801 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	489	Shared Neighborhood Hits	42
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

DUS23_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.241188 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	94	Shared Neighborhood Hits	47
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

PTPRD_HUMAN
θ value	0.0736092 (rank : 26)	NC score	0.099642 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	485	Shared Neighborhood Hits	43
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

DUS11_HUMAN
θ value	0.0961366 (rank : 27)	NC score	0.164621 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

PTN22_HUMAN
θ value	0.21417 (rank : 28)	NC score	0.122281 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTPRS_HUMAN
θ value	0.279714 (rank : 29)	NC score	0.098350 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	472	Shared Neighborhood Hits	43
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTN12_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.123295 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

CD45_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.120764 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	243	Shared Neighborhood Hits	35
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTN12_MOUSE
θ value	0.47712 (rank : 32)	NC score	0.121619 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRE_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.127610 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.128017 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

DUS23_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.207037 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

PTPRB_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.119437 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	242	Shared Neighborhood Hits	46
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRV_MOUSE
θ value	0.62314 (rank : 37)	NC score	0.111995 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

CD45_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.119513 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	178	Shared Neighborhood Hits	34
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

DUS11_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.142437 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

ITIH2_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.027484 (rank : 101)
Query Neighborhood Hits	73	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

IWS1_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.020662 (rank : 104)
Query Neighborhood Hits	73	Target Neighborhood Hits	1241	Shared Neighborhood Hits	7
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PTPM1_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.122874 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTPM1_MOUSE
θ value	1.06291 (rank : 43)	NC score	0.135451 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTPRG_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.103599 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.104942 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	260	Shared Neighborhood Hits	36
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

DUS2_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.048238 (rank : 95)
Query Neighborhood Hits	73	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

MCE1_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.109690 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

PTN6_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.100369 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	45
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRM_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.098141 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	244	Shared Neighborhood Hits	36
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.098487 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	238	Shared Neighborhood Hits	36
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRU_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.101726 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	237	Shared Neighborhood Hits	37
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

CDKN3_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.082177 (rank : 84)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

DUS10_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.048170 (rank : 96)
Query Neighborhood Hits	73	Target Neighborhood Hits	64	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS4_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.049397 (rank : 94)
Query Neighborhood Hits	73	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS4_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.049480 (rank : 93)
Query Neighborhood Hits	73	Target Neighborhood Hits	75	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

MCE1_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.101738 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	O55236	Gene names	Rngtt, Cap1a
Domain Architecture
Description	mRNA capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

MPRI_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.021298 (rank : 103)
Query Neighborhood Hits	73	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

PTN21_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.083639 (rank : 82)
Query Neighborhood Hits	73	Target Neighborhood Hits	143	Shared Neighborhood Hits	32
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.082934 (rank : 83)
Query Neighborhood Hits	73	Target Neighborhood Hits	155	Shared Neighborhood Hits	30
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN5_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.102612 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

DUS10_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.046867 (rank : 98)
Query Neighborhood Hits	73	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

PTN14_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.083867 (rank : 81)
Query Neighborhood Hits	73	Target Neighborhood Hits	142	Shared Neighborhood Hits	41
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

DUS1_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.045180 (rank : 100)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	28
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS1_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.045897 (rank : 99)
Query Neighborhood Hits	73	Target Neighborhood Hits	72	Shared Neighborhood Hits	29
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

IFIT3_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.014053 (rank : 105)
Query Neighborhood Hits	73	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	O14879, Q99634, Q9BSK7	Gene names	IFIT3, IFI60, IFIT4
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (IFIT-4) (Interferon-induced 60 kDa protein) (IFI-60K) (ISG-60) (CIG49) (Retinoic acid-induced gene G protein) (RIG-G).

DUS16_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.053614 (rank : 92)
Query Neighborhood Hits	73	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS2_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.047478 (rank : 97)
Query Neighborhood Hits	73	Target Neighborhood Hits	86	Shared Neighborhood Hits	35
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

EPM2A_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.026100 (rank : 102)
Query Neighborhood Hits	73	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

IWS1_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.008758 (rank : 106)
Query Neighborhood Hits	73	Target Neighborhood Hits	1258	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PCD19_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.003830 (rank : 107)
Query Neighborhood Hits	73	Target Neighborhood Hits	164	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAB3, Q5JTG1, Q5JTG2, Q68DT7, Q9P2N3	Gene names	PCDH19, KIAA1313
Domain Architecture
Description	Protocadherin-19 precursor.

PCD19_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.003822 (rank : 108)
Query Neighborhood Hits	73	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TF3, Q8BL13	Gene names	Pcdh19, Kiaa1313
Domain Architecture	No domain graphic available
Description	Protocadherin-19 precursor.

PCDGG_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.002793 (rank : 109)
Query Neighborhood Hits	73	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UN71, O15099, Q9UN64	Gene names	PCDHGB4, CDH20, FIB2
Domain Architecture
Description	Protocadherin gamma B4 precursor (PCDH-gamma-B4) (Cadherin-20) (Fibroblast cadherin 2).

PTN5_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.099483 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	85	Shared Neighborhood Hits	38
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN11_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.092220 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.092222 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN13_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.068247 (rank : 91)
Query Neighborhood Hits	73	Target Neighborhood Hits	471	Shared Neighborhood Hits	37
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.069557 (rank : 90)
Query Neighborhood Hits	73	Target Neighborhood Hits	426	Shared Neighborhood Hits	41
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN14_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.081600 (rank : 85)
Query Neighborhood Hits	73	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN18_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.097127 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	29
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.102102 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	134	Shared Neighborhood Hits	39
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.092847 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.093167 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN23_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.074365 (rank : 89)
Query Neighborhood Hits	73	Target Neighborhood Hits	646	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.079724 (rank : 86)
Query Neighborhood Hits	73	Target Neighborhood Hits	726	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.090641 (rank : 79)
Query Neighborhood Hits	73	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.090775 (rank : 78)
Query Neighborhood Hits	73	Target Neighborhood Hits	107	Shared Neighborhood Hits	32
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN3_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.074459 (rank : 88)
Query Neighborhood Hits	73	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.077062 (rank : 87)
Query Neighborhood Hits	73	Target Neighborhood Hits	303	Shared Neighborhood Hits	41
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN6_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.094183 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	234	Shared Neighborhood Hits	43
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN7_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.096903 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.096642 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	71	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.094570 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	79	Shared Neighborhood Hits	33
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.094692 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	78	Shared Neighborhood Hits	33
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.092547 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.091417 (rank : 75)
Query Neighborhood Hits	73	Target Neighborhood Hits	120	Shared Neighborhood Hits	33
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.103386 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	207	Shared Neighborhood Hits	44
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.102227 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.094571 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	228	Shared Neighborhood Hits	33
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.094216 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	223	Shared Neighborhood Hits	33
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRN_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.090821 (rank : 77)
Query Neighborhood Hits	73	Target Neighborhood Hits	156	Shared Neighborhood Hits	33
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.090432 (rank : 80)
Query Neighborhood Hits	73	Target Neighborhood Hits	240	Shared Neighborhood Hits	34
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.101128 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.095463 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.096416 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRT_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.094973 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	217	Shared Neighborhood Hits	34
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.095074 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	219	Shared Neighborhood Hits	34
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.094905 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

TENS4_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.091338 (rank : 76)
Query Neighborhood Hits	73	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TENS4_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.091875 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

Hits sorted by NC score

PTEN_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

PTEN_HUMAN
NC score	0.999924 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

TPTE2_HUMAN
NC score	0.872031 (rank : 3)	θ value	7.24236e-58 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

TPTE_HUMAN
NC score	0.871549 (rank : 4)	θ value	4.11246e-53 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

AUXI_HUMAN
NC score	0.686280 (rank : 5)	θ value	6.84181e-24 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

AUXI_MOUSE
NC score	0.682180 (rank : 6)	θ value	5.79196e-23 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

TENS1_HUMAN
NC score	0.622598 (rank : 7)	θ value	9.52487e-34 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	400	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TP4A3_MOUSE
NC score	0.277116 (rank : 8)	θ value	0.000602161 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

TP4A1_HUMAN
NC score	0.269507 (rank : 9)	θ value	0.000461057 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	68	Shared Neighborhood Hits	39
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.269507 (rank : 10)	θ value	0.000461057 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	68	Shared Neighborhood Hits	39
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TP4A3_HUMAN
NC score	0.267112 (rank : 11)	θ value	0.00228821 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	62	Shared Neighborhood Hits	40
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A2_HUMAN
NC score	0.261978 (rank : 12)	θ value	0.000786445 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.261978 (rank : 13)	θ value	0.000786445 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

CC14B_HUMAN
NC score	0.259214 (rank : 14)	θ value	0.00134147 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

GAK_MOUSE
NC score	0.254406 (rank : 15)	θ value	3.28125e-26 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	964	Shared Neighborhood Hits	11
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GAK_HUMAN
NC score	0.248420 (rank : 16)	θ value	7.30988e-26 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	1028	Shared Neighborhood Hits	9
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

CC14A_MOUSE
NC score	0.247641 (rank : 17)	θ value	0.000602161 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	117	Shared Neighborhood Hits	54
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

DUS23_MOUSE
NC score	0.241188 (rank : 18)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	94	Shared Neighborhood Hits	47
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

CC14A_HUMAN
NC score	0.240659 (rank : 19)	θ value	0.00228821 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14B_MOUSE
NC score	0.232395 (rank : 20)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS23_HUMAN
NC score	0.207037 (rank : 21)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

DUS11_HUMAN
NC score	0.164621 (rank : 22)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

DUS11_MOUSE
NC score	0.142437 (rank : 23)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

PTPRA_MOUSE
NC score	0.138140 (rank : 24)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRA_HUMAN
NC score	0.136534 (rank : 25)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPM1_MOUSE
NC score	0.135451 (rank : 26)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTN22_MOUSE
NC score	0.134019 (rank : 27)	θ value	0.00102713 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	179	Shared Neighborhood Hits	34
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPRE_MOUSE
NC score	0.128017 (rank : 28)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_HUMAN
NC score	0.127610 (rank : 29)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTN12_HUMAN
NC score	0.123295 (rank : 30)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTPM1_HUMAN
NC score	0.122874 (rank : 31)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTN22_HUMAN
NC score	0.122281 (rank : 32)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN12_MOUSE
NC score	0.121619 (rank : 33)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

CD45_HUMAN
NC score	0.120764 (rank : 34)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	243	Shared Neighborhood Hits	35
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
NC score	0.119513 (rank : 35)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	178	Shared Neighborhood Hits	34
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRB_HUMAN
NC score	0.119437 (rank : 36)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	242	Shared Neighborhood Hits	46
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRV_MOUSE
NC score	0.111995 (rank : 37)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

MCE1_HUMAN
NC score	0.109690 (rank : 38)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

PTPRG_MOUSE
NC score	0.104942 (rank : 39)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	260	Shared Neighborhood Hits	36
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_HUMAN
NC score	0.103599 (rank : 40)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRD_MOUSE
NC score	0.103463 (rank : 41)	θ value	0.00390308 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRJ_HUMAN
NC score	0.103386 (rank : 42)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	73	Target Neighborhood Hits	207	Shared Neighborhood Hits	44
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN5_HUMAN
NC score	0.102612 (rank : 43)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRJ_MOUSE
NC score	0.102227 (rank : 44)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	73	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN18_MOUSE
NC score	0.102102 (rank : 45)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	73	Target Neighborhood Hits	134	Shared Neighborhood Hits	39
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

MCE1_MOUSE
NC score	0.101738 (rank : 46)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	O55236	Gene names	Rngtt, Cap1a
Domain Architecture
Description	mRNA capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

PTPRU_HUMAN
NC score	0.101726 (rank : 47)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	237	Shared Neighborhood Hits	37
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRO_HUMAN
NC score	0.101128 (rank : 48)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	73	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTN6_MOUSE
NC score	0.100369 (rank : 49)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	45
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRD_HUMAN
NC score	0.099642 (rank : 50)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	485	Shared Neighborhood Hits	43
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTN5_MOUSE
NC score	0.099483 (rank : 51)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	85	Shared Neighborhood Hits	38
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRF_HUMAN
NC score	0.098801 (rank : 52)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	489	Shared Neighborhood Hits	42
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRM_MOUSE
NC score	0.098487 (rank : 53)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	238	Shared Neighborhood Hits	36
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRS_HUMAN
NC score	0.098350 (rank : 54)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	472	Shared Neighborhood Hits	43
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRM_HUMAN
NC score	0.098141 (rank : 55)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	244	Shared Neighborhood Hits	36
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTN18_HUMAN
NC score	0.097127 (rank : 56)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	29
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN7_HUMAN
NC score	0.096903 (rank : 57)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	73	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
NC score	0.096642 (rank : 58)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	73	Target Neighborhood Hits	71	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTPRR_MOUSE
NC score	0.096416 (rank : 59)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	73	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRR_HUMAN
NC score	0.095463 (rank : 60)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	73	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRT_MOUSE
NC score	0.095074 (rank : 61)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	73	Target Neighborhood Hits	219	Shared Neighborhood Hits	34
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.094973 (rank : 62)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	73	Target Neighborhood Hits	217	Shared Neighborhood Hits	34
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRZ_HUMAN
NC score	0.094905 (rank : 63)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	73	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTN9_MOUSE
NC score	0.094692 (rank : 64)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	73	Target Neighborhood Hits	78	Shared Neighborhood Hits	33
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPRK_HUMAN
NC score	0.094571 (rank : 65)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	73	Target Neighborhood Hits	228	Shared Neighborhood Hits	33
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTN9_HUMAN
NC score	0.094570 (rank : 66)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	73	Target Neighborhood Hits	79	Shared Neighborhood Hits	33
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPRK_MOUSE
NC score	0.094216 (rank : 67)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	73	Target Neighborhood Hits	223	Shared Neighborhood Hits	33
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTN6_HUMAN
NC score	0.094183 (rank : 68)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	73	Target Neighborhood Hits	234	Shared Neighborhood Hits	43
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN1_MOUSE
NC score	0.093167 (rank : 69)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	73	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN1_HUMAN
NC score	0.092847 (rank : 70)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	73	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTPR2_HUMAN
NC score	0.092547 (rank : 71)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	73	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTN11_MOUSE
NC score	0.092222 (rank : 72)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.092220 (rank : 73)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

TENS4_MOUSE
NC score	0.091875 (rank : 74)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

PTPR2_MOUSE
NC score	0.091417 (rank : 75)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	73	Target Neighborhood Hits	120	Shared Neighborhood Hits	33
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

TENS4_HUMAN
NC score	0.091338 (rank : 76)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	73	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

PTPRN_HUMAN
NC score	0.090821 (rank : 77)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	73	Target Neighborhood Hits	156	Shared Neighborhood Hits	33
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTN2_MOUSE
NC score	0.090775 (rank : 78)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	73	Target Neighborhood Hits	107	Shared Neighborhood Hits	32
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN2_HUMAN
NC score	0.090641 (rank : 79)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	73	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTPRN_MOUSE
NC score	0.090432 (rank : 80)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	73	Target Neighborhood Hits	240	Shared Neighborhood Hits	34
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTN14_MOUSE
NC score	0.083867 (rank : 81)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	142	Shared Neighborhood Hits	41
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN21_HUMAN
NC score	0.083639 (rank : 82)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	143	Shared Neighborhood Hits	32
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
NC score	0.082934 (rank : 83)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	155	Shared Neighborhood Hits	30
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

CDKN3_HUMAN
NC score	0.082177 (rank : 84)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

PTN14_HUMAN
NC score	0.081600 (rank : 85)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	73	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN23_MOUSE
NC score	0.079724 (rank : 86)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	73	Target Neighborhood Hits	726	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN4_HUMAN
NC score	0.077062 (rank : 87)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	73	Target Neighborhood Hits	303	Shared Neighborhood Hits	41
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN3_HUMAN
NC score	0.074459 (rank : 88)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	73	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN23_HUMAN
NC score	0.074365 (rank : 89)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	73	Target Neighborhood Hits	646	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN13_MOUSE
NC score	0.069557 (rank : 90)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	73	Target Neighborhood Hits	426	Shared Neighborhood Hits	41
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.068247 (rank : 91)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	73	Target Neighborhood Hits	471	Shared Neighborhood Hits	37
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

DUS16_HUMAN
NC score	0.053614 (rank : 92)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS4_MOUSE
NC score	0.049480 (rank : 93)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	75	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS4_HUMAN
NC score	0.049397 (rank : 94)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS2_HUMAN
NC score	0.048238 (rank : 95)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS10_HUMAN
NC score	0.048170 (rank : 96)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	64	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS2_MOUSE
NC score	0.047478 (rank : 97)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	86	Shared Neighborhood Hits	35
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS10_MOUSE
NC score	0.046867 (rank : 98)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS1_MOUSE
NC score	0.045897 (rank : 99)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	72	Shared Neighborhood Hits	29
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS1_HUMAN
NC score	0.045180 (rank : 100)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	28
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

ITIH2_HUMAN
NC score	0.027484 (rank : 101)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

EPM2A_HUMAN
NC score	0.026100 (rank : 102)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

MPRI_HUMAN
NC score	0.021298 (rank : 103)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

IWS1_HUMAN
NC score	0.020662 (rank : 104)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	1241	Shared Neighborhood Hits	7
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IFIT3_HUMAN
NC score	0.014053 (rank : 105)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	O14879, Q99634, Q9BSK7	Gene names	IFIT3, IFI60, IFIT4
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (IFIT-4) (Interferon-induced 60 kDa protein) (IFI-60K) (ISG-60) (CIG49) (Retinoic acid-induced gene G protein) (RIG-G).

IWS1_MOUSE
NC score	0.008758 (rank : 106)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	1258	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PCD19_HUMAN
NC score	0.003830 (rank : 107)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	164	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAB3, Q5JTG1, Q5JTG2, Q68DT7, Q9P2N3	Gene names	PCDH19, KIAA1313
Domain Architecture
Description	Protocadherin-19 precursor.

PCD19_MOUSE
NC score	0.003822 (rank : 108)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TF3, Q8BL13	Gene names	Pcdh19, Kiaa1313
Domain Architecture	No domain graphic available
Description	Protocadherin-19 precursor.

PCDGG_HUMAN
NC score	0.002793 (rank : 109)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UN71, O15099, Q9UN64	Gene names	PCDHGB4, CDH20, FIB2
Domain Architecture
Description	Protocadherin gamma B4 precursor (PCDH-gamma-B4) (Cadherin-20) (Fibroblast cadherin 2).