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Network neighborhood for query Sequence : MPRI_HUMAN

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MPRI_HUMAN
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MPRI_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

MPRI_MOUSE
θ value	0 (rank : 2)	NC score	0.992617 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	51	Shared Neighborhood Hits	30
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

MMP2_HUMAN
θ value	1.47974e-10 (rank : 3)	NC score	0.262698 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP2_MOUSE
θ value	7.34386e-10 (rank : 4)	NC score	0.259677 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

MMP9_HUMAN
θ value	2.13673e-09 (rank : 5)	NC score	0.284082 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP9_MOUSE
θ value	2.13673e-09 (rank : 6)	NC score	0.284525 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

SEL1L_HUMAN
θ value	3.64472e-09 (rank : 7)	NC score	0.436494 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
θ value	3.64472e-09 (rank : 8)	NC score	0.433332 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	62	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

HGFA_HUMAN
θ value	4.0297e-08 (rank : 9)	NC score	0.120019 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	436	Shared Neighborhood Hits	24
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FINC_HUMAN
θ value	1.17247e-07 (rank : 10)	NC score	0.220719 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	302	Shared Neighborhood Hits	22
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	1.17247e-07 (rank : 11)	NC score	0.220257 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	309	Shared Neighborhood Hits	23
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

HGFA_MOUSE
θ value	1.17247e-07 (rank : 12)	NC score	0.118973 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	419	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

MRC1_MOUSE
θ value	2.21117e-06 (rank : 13)	NC score	0.261892 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

MPRD_HUMAN
θ value	2.88788e-06 (rank : 14)	NC score	0.255759 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P20645	Gene names	M6PR, MPR46, MPRD
Domain Architecture
Description	Cation-dependent mannose-6-phosphate receptor precursor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46).

MPRD_MOUSE
θ value	2.88788e-06 (rank : 15)	NC score	0.266868 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P24668	Gene names	M6pr, 46mpr
Domain Architecture
Description	Cation-dependent mannose-6-phosphate receptor precursor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46).

LY75_HUMAN
θ value	3.77169e-06 (rank : 16)	NC score	0.262225 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	169	Shared Neighborhood Hits	19
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

MRC1_HUMAN
θ value	8.40245e-06 (rank : 17)	NC score	0.253003 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	157	Shared Neighborhood Hits	19
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

FA12_HUMAN
θ value	1.43324e-05 (rank : 18)	NC score	0.114623 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

MRC2_HUMAN
θ value	1.43324e-05 (rank : 19)	NC score	0.251619 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

MRC2_MOUSE
θ value	1.43324e-05 (rank : 20)	NC score	0.252562 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

LY75_MOUSE
θ value	5.44631e-05 (rank : 21)	NC score	0.252683 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

RBM19_HUMAN
θ value	0.0563607 (rank : 22)	NC score	0.028594 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

SL9A5_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.033285 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q14940, Q9Y626	Gene names	SLC9A5, NHE5
Domain Architecture
Description	Sodium/hydrogen exchanger 5 (Na(+)/H(+) exchanger 5) (NHE-5) (Solute carrier family 9 member 5).

TNR6A_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.033957 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

MYBB_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.023236 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

ELOA1_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.024177 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

NOTC4_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.020037 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	905	Shared Neighborhood Hits	9
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

3HAO_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.032771 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P46952, Q53QZ7, Q8N6N9	Gene names	HAAO
Domain Architecture
Description	3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-HAO) (3- hydroxyanthranilic acid dioxygenase) (3-hydroxyanthranilate oxygenase).

MYH4_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.013983 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	1476	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.013550 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	1600	Shared Neighborhood Hits	14
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH1_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.013776 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	1461	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

NOLC1_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.019970 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	452	Shared Neighborhood Hits	7
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

GLU2B_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.046610 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

CUBN_MOUSE
θ value	4.03905 (rank : 34)	NC score	0.015299 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	477	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

EAN57_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.024216 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

MYH3_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.012042 (rank : 68)
Query Neighborhood Hits	67	Target Neighborhood Hits	1660	Shared Neighborhood Hits	12
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PTEN_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.021299 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.021298 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

RUSC2_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.024900 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SGCD_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.015137 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P82347	Gene names	Sgcd
Domain Architecture
Description	Delta-sarcoglycan (SG-delta) (35 kDa dystrophin-associated glycoprotein) (35DAG).

TITIN_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.008967 (rank : 74)
Query Neighborhood Hits	67	Target Neighborhood Hits	2923	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

GNPTG_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.022927 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q6S5C2, Q7TNE0, Q8C5J3	Gene names	Gnptg, Mdcp1
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunit gamma precursor (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine- 1-phosphotransferase, subunit gamma) (M6PR domain-containing protein 1).

GRP78_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.014886 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	218	Shared Neighborhood Hits	11
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.014844 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	216	Shared Neighborhood Hits	11
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

LRBA_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.020785 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

COKA1_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.025678 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

DMXL2_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.008071 (rank : 75)
Query Neighborhood Hits	67	Target Neighborhood Hits	374	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

GLU2B_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.042850 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

MYH7_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.012186 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	1559	Shared Neighborhood Hits	14
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

CTR9_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.009747 (rank : 72)
Query Neighborhood Hits	67	Target Neighborhood Hits	427	Shared Neighborhood Hits	8
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

FETUB_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.011993 (rank : 69)
Query Neighborhood Hits	67	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGM5, Q1RMZ0, Q6DK58, Q6GRB6, Q9Y6Z0	Gene names	FETUB
Domain Architecture
Description	Fetuin-B precursor (Gugu) (IRL685) (16G2).

IWS1_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.006584 (rank : 77)
Query Neighborhood Hits	67	Target Neighborhood Hits	1241	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LRP2_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.009086 (rank : 73)
Query Neighborhood Hits	67	Target Neighborhood Hits	573	Shared Neighborhood Hits	12
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LTBP4_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.009829 (rank : 71)
Query Neighborhood Hits	67	Target Neighborhood Hits	607	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MYH13_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.011981 (rank : 70)
Query Neighborhood Hits	67	Target Neighborhood Hits	1504	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH1_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.012254 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	1478	Shared Neighborhood Hits	12
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH2_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.012268 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	1491	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYOM1_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.019104 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	405	Shared Neighborhood Hits	8
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

OR2Z1_HUMAN
θ value	8.99809 (rank : 59)	NC score	-0.001679 (rank : 85)
Query Neighborhood Hits	67	Target Neighborhood Hits	755	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NG97, Q6IFK0, Q96R25	Gene names	OR2Z1, OR2Z2
Domain Architecture
Description	Olfactory receptor 2Z1 (Olfactory receptor OR19-4).

PHLPL_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.003103 (rank : 84)
Query Neighborhood Hits	67	Target Neighborhood Hits	303	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

PTN6_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.003339 (rank : 83)
Query Neighborhood Hits	67	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRN_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.004122 (rank : 82)
Query Neighborhood Hits	67	Target Neighborhood Hits	240	Shared Neighborhood Hits	3
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RARG1_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.006145 (rank : 79)
Query Neighborhood Hits	67	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.006160 (rank : 78)
Query Neighborhood Hits	67	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.006109 (rank : 81)
Query Neighborhood Hits	67	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.006119 (rank : 80)
Query Neighborhood Hits	67	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

SYNP2_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.007234 (rank : 76)
Query Neighborhood Hits	67	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

CD302_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.073221 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

CD302_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.072312 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

CHODL_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.056023 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CHODL_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.056055 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

EMBP_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.050664 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q61878	Gene names	Prg2, Mbp-1
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (Proteoglycan 2, bone marrow).

MMP10_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.050532 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP10_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.051099 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP11_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.051524 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP11_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.051746 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP13_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.051904 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP13_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.051285 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.050493 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP26_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.053759 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP3_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.050257 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP3_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.050246 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

MMP7_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.058284 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP7_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.058292 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

PRG3_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.051456 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

Hits sorted by NC score

MPRI_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

MPRI_MOUSE
NC score	0.992617 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	51	Shared Neighborhood Hits	30
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

SEL1L_HUMAN
NC score	0.436494 (rank : 3)	θ value	3.64472e-09 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
NC score	0.433332 (rank : 4)	θ value	3.64472e-09 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	62	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

MMP9_MOUSE
NC score	0.284525 (rank : 5)	θ value	2.13673e-09 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

MMP9_HUMAN
NC score	0.284082 (rank : 6)	θ value	2.13673e-09 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MPRD_MOUSE
NC score	0.266868 (rank : 7)	θ value	2.88788e-06 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P24668	Gene names	M6pr, 46mpr
Domain Architecture
Description	Cation-dependent mannose-6-phosphate receptor precursor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46).

MMP2_HUMAN
NC score	0.262698 (rank : 8)	θ value	1.47974e-10 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

LY75_HUMAN
NC score	0.262225 (rank : 9)	θ value	3.77169e-06 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	169	Shared Neighborhood Hits	19
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

MRC1_MOUSE
NC score	0.261892 (rank : 10)	θ value	2.21117e-06 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

MMP2_MOUSE
NC score	0.259677 (rank : 11)	θ value	7.34386e-10 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

MPRD_HUMAN
NC score	0.255759 (rank : 12)	θ value	2.88788e-06 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P20645	Gene names	M6PR, MPR46, MPRD
Domain Architecture
Description	Cation-dependent mannose-6-phosphate receptor precursor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46).

MRC1_HUMAN
NC score	0.253003 (rank : 13)	θ value	8.40245e-06 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	157	Shared Neighborhood Hits	19
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

LY75_MOUSE
NC score	0.252683 (rank : 14)	θ value	5.44631e-05 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

MRC2_MOUSE
NC score	0.252562 (rank : 15)	θ value	1.43324e-05 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

MRC2_HUMAN
NC score	0.251619 (rank : 16)	θ value	1.43324e-05 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

FINC_HUMAN
NC score	0.220719 (rank : 17)	θ value	1.17247e-07 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	302	Shared Neighborhood Hits	22
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.220257 (rank : 18)	θ value	1.17247e-07 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	309	Shared Neighborhood Hits	23
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

HGFA_HUMAN
NC score	0.120019 (rank : 19)	θ value	4.0297e-08 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	436	Shared Neighborhood Hits	24
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
NC score	0.118973 (rank : 20)	θ value	1.17247e-07 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	419	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FA12_HUMAN
NC score	0.114623 (rank : 21)	θ value	1.43324e-05 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

CD302_HUMAN
NC score	0.073221 (rank : 22)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	67	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

CD302_MOUSE
NC score	0.072312 (rank : 23)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	67	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

MMP7_MOUSE
NC score	0.058292 (rank : 24)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	67	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP7_HUMAN
NC score	0.058284 (rank : 25)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	67	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

CHODL_MOUSE
NC score	0.056055 (rank : 26)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	67	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CHODL_HUMAN
NC score	0.056023 (rank : 27)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	67	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

MMP26_HUMAN
NC score	0.053759 (rank : 28)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	67	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP13_HUMAN
NC score	0.051904 (rank : 29)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	67	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP11_MOUSE
NC score	0.051746 (rank : 30)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP11_HUMAN
NC score	0.051524 (rank : 31)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	67	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

PRG3_HUMAN
NC score	0.051456 (rank : 32)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	67	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

MMP13_MOUSE
NC score	0.051285 (rank : 33)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	67	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP10_MOUSE
NC score	0.051099 (rank : 34)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	67	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

EMBP_MOUSE
NC score	0.050664 (rank : 35)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	67	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q61878	Gene names	Prg2, Mbp-1
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (Proteoglycan 2, bone marrow).

MMP10_HUMAN
NC score	0.050532 (rank : 36)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP1_HUMAN
NC score	0.050493 (rank : 37)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	67	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP3_HUMAN
NC score	0.050257 (rank : 38)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP3_MOUSE
NC score	0.050246 (rank : 39)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

GLU2B_HUMAN
NC score	0.046610 (rank : 40)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLU2B_MOUSE
NC score	0.042850 (rank : 41)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

TNR6A_HUMAN
NC score	0.033957 (rank : 42)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

SL9A5_HUMAN
NC score	0.033285 (rank : 43)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q14940, Q9Y626	Gene names	SLC9A5, NHE5
Domain Architecture
Description	Sodium/hydrogen exchanger 5 (Na(+)/H(+) exchanger 5) (NHE-5) (Solute carrier family 9 member 5).

3HAO_HUMAN
NC score	0.032771 (rank : 44)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P46952, Q53QZ7, Q8N6N9	Gene names	HAAO
Domain Architecture
Description	3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-HAO) (3- hydroxyanthranilic acid dioxygenase) (3-hydroxyanthranilate oxygenase).

RBM19_HUMAN
NC score	0.028594 (rank : 45)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

COKA1_HUMAN
NC score	0.025678 (rank : 46)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

RUSC2_HUMAN
NC score	0.024900 (rank : 47)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

EAN57_HUMAN
NC score	0.024216 (rank : 48)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

ELOA1_MOUSE
NC score	0.024177 (rank : 49)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MYBB_HUMAN
NC score	0.023236 (rank : 50)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

GNPTG_MOUSE
NC score	0.022927 (rank : 51)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q6S5C2, Q7TNE0, Q8C5J3	Gene names	Gnptg, Mdcp1
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunit gamma precursor (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine- 1-phosphotransferase, subunit gamma) (M6PR domain-containing protein 1).

PTEN_HUMAN
NC score	0.021299 (rank : 52)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.021298 (rank : 53)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

LRBA_HUMAN
NC score	0.020785 (rank : 54)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

NOTC4_HUMAN
NC score	0.020037 (rank : 55)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	905	Shared Neighborhood Hits	9
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOLC1_HUMAN
NC score	0.019970 (rank : 56)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	452	Shared Neighborhood Hits	7
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

MYOM1_HUMAN
NC score	0.019104 (rank : 57)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	405	Shared Neighborhood Hits	8
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

CUBN_MOUSE
NC score	0.015299 (rank : 58)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	477	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

SGCD_MOUSE
NC score	0.015137 (rank : 59)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P82347	Gene names	Sgcd
Domain Architecture
Description	Delta-sarcoglycan (SG-delta) (35 kDa dystrophin-associated glycoprotein) (35DAG).

GRP78_HUMAN
NC score	0.014886 (rank : 60)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	218	Shared Neighborhood Hits	11
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
NC score	0.014844 (rank : 61)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	216	Shared Neighborhood Hits	11
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

MYH4_MOUSE
NC score	0.013983 (rank : 62)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	1476	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH1_MOUSE
NC score	0.013776 (rank : 63)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	1461	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH8_MOUSE
NC score	0.013550 (rank : 64)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	1600	Shared Neighborhood Hits	14
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH2_HUMAN
NC score	0.012268 (rank : 65)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	1491	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH1_HUMAN
NC score	0.012254 (rank : 66)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	1478	Shared Neighborhood Hits	12
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH7_HUMAN
NC score	0.012186 (rank : 67)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	1559	Shared Neighborhood Hits	14
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH3_HUMAN
NC score	0.012042 (rank : 68)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	1660	Shared Neighborhood Hits	12
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

FETUB_HUMAN
NC score	0.011993 (rank : 69)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGM5, Q1RMZ0, Q6DK58, Q6GRB6, Q9Y6Z0	Gene names	FETUB
Domain Architecture
Description	Fetuin-B precursor (Gugu) (IRL685) (16G2).

MYH13_HUMAN
NC score	0.011981 (rank : 70)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	1504	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

LTBP4_MOUSE
NC score	0.009829 (rank : 71)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	607	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

CTR9_MOUSE
NC score	0.009747 (rank : 72)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	427	Shared Neighborhood Hits	8
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

LRP2_HUMAN
NC score	0.009086 (rank : 73)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	573	Shared Neighborhood Hits	12
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

TITIN_HUMAN
NC score	0.008967 (rank : 74)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	2923	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

DMXL2_HUMAN
NC score	0.008071 (rank : 75)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	374	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

SYNP2_HUMAN
NC score	0.007234 (rank : 76)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

IWS1_HUMAN
NC score	0.006584 (rank : 77)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	1241	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RARG1_MOUSE
NC score	0.006160 (rank : 78)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG1_HUMAN
NC score	0.006145 (rank : 79)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_MOUSE
NC score	0.006119 (rank : 80)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARG2_HUMAN
NC score	0.006109 (rank : 81)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

PTPRN_MOUSE
NC score	0.004122 (rank : 82)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	240	Shared Neighborhood Hits	3
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTN6_MOUSE
NC score	0.003339 (rank : 83)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PHLPL_MOUSE
NC score	0.003103 (rank : 84)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	303	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

OR2Z1_HUMAN
NC score	-0.001679 (rank : 85)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	755	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NG97, Q6IFK0, Q96R25	Gene names	OR2Z1, OR2Z2
Domain Architecture
Description	Olfactory receptor 2Z1 (Olfactory receptor OR19-4).