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Network neighborhood for query Sequence : MPRI_MOUSE

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MPRI_MOUSE
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MPRI_HUMAN
θ value	0 (rank : 1)	NC score	0.992617 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

MPRI_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

MMP2_HUMAN
θ value	1.47974e-10 (rank : 3)	NC score	0.267652 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP9_HUMAN
θ value	4.30538e-10 (rank : 4)	NC score	0.290011 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP9_MOUSE
θ value	4.30538e-10 (rank : 5)	NC score	0.290683 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

MMP2_MOUSE
θ value	7.34386e-10 (rank : 6)	NC score	0.264661 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

SEL1L_HUMAN
θ value	9.59137e-10 (rank : 7)	NC score	0.445356 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
θ value	9.59137e-10 (rank : 8)	NC score	0.442330 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

HGFA_HUMAN
θ value	2.79066e-09 (rank : 9)	NC score	0.125975 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	436	Shared Neighborhood Hits	24
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	4.76016e-09 (rank : 10)	NC score	0.125099 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	419	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FINC_HUMAN
θ value	8.11959e-09 (rank : 11)	NC score	0.225829 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	302	Shared Neighborhood Hits	21
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	8.11959e-09 (rank : 12)	NC score	0.225370 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	309	Shared Neighborhood Hits	22
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FA12_HUMAN
θ value	4.45536e-07 (rank : 13)	NC score	0.120787 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	425	Shared Neighborhood Hits	25
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

LY75_HUMAN
θ value	6.43352e-06 (rank : 14)	NC score	0.257914 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	169	Shared Neighborhood Hits	19
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

MRC2_HUMAN
θ value	1.43324e-05 (rank : 15)	NC score	0.249512 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

MRC2_MOUSE
θ value	1.43324e-05 (rank : 16)	NC score	0.250426 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

MRC1_MOUSE
θ value	1.87187e-05 (rank : 17)	NC score	0.257779 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

MRC1_HUMAN
θ value	7.1131e-05 (rank : 18)	NC score	0.248968 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	157	Shared Neighborhood Hits	19
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

LY75_MOUSE
θ value	0.000461057 (rank : 19)	NC score	0.247984 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

MPRD_MOUSE
θ value	0.000786445 (rank : 20)	NC score	0.228771 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P24668	Gene names	M6pr, 46mpr
Domain Architecture
Description	Cation-dependent mannose-6-phosphate receptor precursor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46).

MPRD_HUMAN
θ value	0.00665767 (rank : 21)	NC score	0.217054 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P20645	Gene names	M6PR, MPR46, MPRD
Domain Architecture
Description	Cation-dependent mannose-6-phosphate receptor precursor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46).

NOTC4_HUMAN
θ value	0.163984 (rank : 22)	NC score	0.023943 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	905	Shared Neighborhood Hits	10
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

GLU2B_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.059118 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	377	Shared Neighborhood Hits	6
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

LRBA_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.027677 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

GLU2B_MOUSE
θ value	0.62314 (rank : 25)	NC score	0.055677 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	357	Shared Neighborhood Hits	7
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

CAD23_MOUSE
θ value	0.813845 (rank : 26)	NC score	0.009320 (rank : 66)
Query Neighborhood Hits	51	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

MUG1_MOUSE
θ value	0.813845 (rank : 27)	NC score	0.018621 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

BTNL8_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.012499 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

RBM19_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.014203 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

DLG7_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.025229 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

RBFAL_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.034110 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0V3, Q6PF07, Q8WZ65, Q9H776	Gene names	C18orf22
Domain Architecture	No domain graphic available
Description	Putative ribosome-binding factor A, mitochondrial precursor.

ATS20_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.008420 (rank : 68)
Query Neighborhood Hits	51	Target Neighborhood Hits	192	Shared Neighborhood Hits	4
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

GRP78_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.016595 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	218	Shared Neighborhood Hits	5
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.016601 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

TNR8_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.023378 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

RUSC2_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.025956 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CUBN_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.019034 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	477	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

ATS12_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.006770 (rank : 69)
Query Neighborhood Hits	51	Target Neighborhood Hits	220	Shared Neighborhood Hits	4
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

P52K_MOUSE
θ value	5.27518 (rank : 39)	NC score	0.015298 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CUX1, Q80Y58	Gene names	Prkrir, Thap0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (THAP domain-containing protein 0).

ZADH1_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.015908 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8N7, Q6MZH8	Gene names	ZADH1
Domain Architecture	No domain graphic available
Description	Zinc-binding alcohol dehydrogenase domain-containing protein 1 (EC 1.-.-.-).

CAF1A_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.009239 (rank : 67)
Query Neighborhood Hits	51	Target Neighborhood Hits	750	Shared Neighborhood Hits	5
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

LRP2_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.011456 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	573	Shared Neighborhood Hits	14
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

NAR3_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.013333 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2G4, Q8R2F9, Q8R2G0, Q8R2G1, Q8R2G2, Q8R2G3	Gene names	Art3
Domain Architecture
Description	Ecto-ADP-ribosyltransferase 3 precursor (EC 2.4.2.31) (NAD(P)(+)-- arginine ADP-ribosyltransferase 3) (Mono(ADP-ribosyl)transferase 3).

NELL1_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.013817 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	451	Shared Neighborhood Hits	10
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SMYD1_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.011080 (rank : 65)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

TF3C1_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.012771 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

CABYR_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.012672 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

CUBN_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.015090 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	482	Shared Neighborhood Hits	9
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

RIMB1_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.006390 (rank : 70)
Query Neighborhood Hits	51	Target Neighborhood Hits	1376	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SEM4F_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.003601 (rank : 71)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SLIK1_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.002372 (rank : 72)
Query Neighborhood Hits	51	Target Neighborhood Hits	333	Shared Neighborhood Hits	2
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

CD302_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.068926 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

CD302_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.068272 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

CHODL_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.052624 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CHODL_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.052704 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

MMP10_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.051750 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP10_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.052435 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP11_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.052821 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP11_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.053021 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP12_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.050724 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

MMP13_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.053140 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP13_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.052614 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP1A_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.051111 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP1_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.051683 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP20_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.050082 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O60882, Q6DKT9	Gene names	MMP20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP20_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.050138 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P57748	Gene names	Mmp20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP26_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.055188 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP3_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.051487 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP3_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.051440 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

MMP7_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.059618 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP7_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.059718 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP8_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.050018 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

Hits sorted by NC score

MPRI_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

MPRI_HUMAN
NC score	0.992617 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

SEL1L_HUMAN
NC score	0.445356 (rank : 3)	θ value	9.59137e-10 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
NC score	0.442330 (rank : 4)	θ value	9.59137e-10 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

MMP9_MOUSE
NC score	0.290683 (rank : 5)	θ value	4.30538e-10 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

MMP9_HUMAN
NC score	0.290011 (rank : 6)	θ value	4.30538e-10 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP2_HUMAN
NC score	0.267652 (rank : 7)	θ value	1.47974e-10 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP2_MOUSE
NC score	0.264661 (rank : 8)	θ value	7.34386e-10 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

LY75_HUMAN
NC score	0.257914 (rank : 9)	θ value	6.43352e-06 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	169	Shared Neighborhood Hits	19
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

MRC1_MOUSE
NC score	0.257779 (rank : 10)	θ value	1.87187e-05 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

MRC2_MOUSE
NC score	0.250426 (rank : 11)	θ value	1.43324e-05 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	159	Shared Neighborhood Hits	19
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

MRC2_HUMAN
NC score	0.249512 (rank : 12)	θ value	1.43324e-05 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

MRC1_HUMAN
NC score	0.248968 (rank : 13)	θ value	7.1131e-05 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	157	Shared Neighborhood Hits	19
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

LY75_MOUSE
NC score	0.247984 (rank : 14)	θ value	0.000461057 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

MPRD_MOUSE
NC score	0.228771 (rank : 15)	θ value	0.000786445 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	P24668	Gene names	M6pr, 46mpr
Domain Architecture
Description	Cation-dependent mannose-6-phosphate receptor precursor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46).

FINC_HUMAN
NC score	0.225829 (rank : 16)	θ value	8.11959e-09 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	302	Shared Neighborhood Hits	21
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.225370 (rank : 17)	θ value	8.11959e-09 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	309	Shared Neighborhood Hits	22
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MPRD_HUMAN
NC score	0.217054 (rank : 18)	θ value	0.00665767 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P20645	Gene names	M6PR, MPR46, MPRD
Domain Architecture
Description	Cation-dependent mannose-6-phosphate receptor precursor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46).

HGFA_HUMAN
NC score	0.125975 (rank : 19)	θ value	2.79066e-09 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	436	Shared Neighborhood Hits	24
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
NC score	0.125099 (rank : 20)	θ value	4.76016e-09 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	419	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FA12_HUMAN
NC score	0.120787 (rank : 21)	θ value	4.45536e-07 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	425	Shared Neighborhood Hits	25
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

CD302_HUMAN
NC score	0.068926 (rank : 22)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

CD302_MOUSE
NC score	0.068272 (rank : 23)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

MMP7_MOUSE
NC score	0.059718 (rank : 24)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP7_HUMAN
NC score	0.059618 (rank : 25)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	51	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

GLU2B_HUMAN
NC score	0.059118 (rank : 26)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	377	Shared Neighborhood Hits	6
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLU2B_MOUSE
NC score	0.055677 (rank : 27)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	357	Shared Neighborhood Hits	7
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

MMP26_HUMAN
NC score	0.055188 (rank : 28)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

MMP13_HUMAN
NC score	0.053140 (rank : 29)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP11_MOUSE
NC score	0.053021 (rank : 30)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q02853	Gene names	Mmp11
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP11_HUMAN
NC score	0.052821 (rank : 31)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

CHODL_MOUSE
NC score	0.052704 (rank : 32)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CHODL_HUMAN
NC score	0.052624 (rank : 33)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

MMP13_MOUSE
NC score	0.052614 (rank : 34)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP10_MOUSE
NC score	0.052435 (rank : 35)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP10_HUMAN
NC score	0.051750 (rank : 36)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP1_HUMAN
NC score	0.051683 (rank : 37)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP3_HUMAN
NC score	0.051487 (rank : 38)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P08254, Q3B7S0	Gene names	MMP3, STMY1
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1).

MMP3_MOUSE
NC score	0.051440 (rank : 39)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P28862	Gene names	Mmp3
Domain Architecture
Description	Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1) (EMS-2).

MMP1A_MOUSE
NC score	0.051111 (rank : 40)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP12_MOUSE
NC score	0.050724 (rank : 41)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

MMP20_MOUSE
NC score	0.050138 (rank : 42)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P57748	Gene names	Mmp20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP20_HUMAN
NC score	0.050082 (rank : 43)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O60882, Q6DKT9	Gene names	MMP20
Domain Architecture
Description	Matrix metalloproteinase-20 precursor (EC 3.4.24.-) (MMP-20) (Enamel metalloproteinase) (Enamelysin).

MMP8_MOUSE
NC score	0.050018 (rank : 44)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

RBFAL_HUMAN
NC score	0.034110 (rank : 45)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0V3, Q6PF07, Q8WZ65, Q9H776	Gene names	C18orf22
Domain Architecture	No domain graphic available
Description	Putative ribosome-binding factor A, mitochondrial precursor.

LRBA_HUMAN
NC score	0.027677 (rank : 46)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

RUSC2_HUMAN
NC score	0.025956 (rank : 47)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

DLG7_MOUSE
NC score	0.025229 (rank : 48)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

NOTC4_HUMAN
NC score	0.023943 (rank : 49)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	905	Shared Neighborhood Hits	10
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TNR8_MOUSE
NC score	0.023378 (rank : 50)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

CUBN_MOUSE
NC score	0.019034 (rank : 51)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	477	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

MUG1_MOUSE
NC score	0.018621 (rank : 52)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

GRP78_MOUSE
NC score	0.016601 (rank : 53)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

GRP78_HUMAN
NC score	0.016595 (rank : 54)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	218	Shared Neighborhood Hits	5
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

ZADH1_HUMAN
NC score	0.015908 (rank : 55)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8N7, Q6MZH8	Gene names	ZADH1
Domain Architecture	No domain graphic available
Description	Zinc-binding alcohol dehydrogenase domain-containing protein 1 (EC 1.-.-.-).

P52K_MOUSE
NC score	0.015298 (rank : 56)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CUX1, Q80Y58	Gene names	Prkrir, Thap0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (THAP domain-containing protein 0).

CUBN_HUMAN
NC score	0.015090 (rank : 57)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	482	Shared Neighborhood Hits	9
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

RBM19_MOUSE
NC score	0.014203 (rank : 58)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

NELL1_HUMAN
NC score	0.013817 (rank : 59)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	451	Shared Neighborhood Hits	10
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NAR3_MOUSE
NC score	0.013333 (rank : 60)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2G4, Q8R2F9, Q8R2G0, Q8R2G1, Q8R2G2, Q8R2G3	Gene names	Art3
Domain Architecture
Description	Ecto-ADP-ribosyltransferase 3 precursor (EC 2.4.2.31) (NAD(P)(+)-- arginine ADP-ribosyltransferase 3) (Mono(ADP-ribosyl)transferase 3).

TF3C1_HUMAN
NC score	0.012771 (rank : 61)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

CABYR_HUMAN
NC score	0.012672 (rank : 62)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

BTNL8_HUMAN
NC score	0.012499 (rank : 63)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

LRP2_HUMAN
NC score	0.011456 (rank : 64)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	573	Shared Neighborhood Hits	14
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

SMYD1_HUMAN
NC score	0.011080 (rank : 65)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

CAD23_MOUSE
NC score	0.009320 (rank : 66)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAF1A_HUMAN
NC score	0.009239 (rank : 67)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	750	Shared Neighborhood Hits	5
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

ATS20_HUMAN
NC score	0.008420 (rank : 68)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	192	Shared Neighborhood Hits	4
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS12_MOUSE
NC score	0.006770 (rank : 69)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	220	Shared Neighborhood Hits	4
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

RIMB1_MOUSE
NC score	0.006390 (rank : 70)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	1376	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SEM4F_MOUSE
NC score	0.003601 (rank : 71)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SLIK1_MOUSE
NC score	0.002372 (rank : 72)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	333	Shared Neighborhood Hits	2
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.