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Network neighborhood for query Sequence : DUS11_HUMAN

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DUS11_HUMAN
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DUS11_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

DUS11_MOUSE
θ value	3.89193e-128 (rank : 2)	NC score	0.977154 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

MCE1_HUMAN
θ value	1.5773e-20 (rank : 3)	NC score	0.656453 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

MCE1_MOUSE
θ value	1.74391e-19 (rank : 4)	NC score	0.651511 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	O55236	Gene names	Rngtt, Cap1a
Domain Architecture
Description	mRNA capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

TPTE_HUMAN
θ value	0.00228821 (rank : 5)	NC score	0.207489 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	19
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

PTPM1_MOUSE
θ value	0.0193708 (rank : 6)	NC score	0.234877 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	64	Shared Neighborhood Hits	20
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

TPTE2_HUMAN
θ value	0.0193708 (rank : 7)	NC score	0.183673 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

DUS23_HUMAN
θ value	0.0431538 (rank : 8)	NC score	0.246008 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

DUS23_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.241904 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

PTEN_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.164622 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	0.0961366 (rank : 11)	NC score	0.164621 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	73	Shared Neighborhood Hits	25
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

DUS2_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.068815 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS2_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.063267 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

PTPRJ_HUMAN
θ value	0.62314 (rank : 14)	NC score	0.051221 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

CC14A_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.120060 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	133	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

PTPRJ_MOUSE
θ value	1.81305 (rank : 16)	NC score	0.045319 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

DUS16_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.066894 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS1_MOUSE
θ value	2.36792 (rank : 18)	NC score	0.049647 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

CC14A_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.115125 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

PTPM1_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.182446 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	60	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

ZBT24_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.000785 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	870	Shared Neighborhood Hits	2
SwissProt Accessions	O43167, Q5TED5, Q8N455	Gene names	ZBTB24, KIAA0441, ZNF450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450).

BRD4_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.011241 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	851	Shared Neighborhood Hits	3
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CASR_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.010070 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

PTN14_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.024702 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

AMOT_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.011262 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	712	Shared Neighborhood Hits	3
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

CC14B_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.127533 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PTPRA_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.034481 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.034876 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRD_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.024332 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	485	Shared Neighborhood Hits	18
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.024532 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	491	Shared Neighborhood Hits	18
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRS_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.024224 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	472	Shared Neighborhood Hits	18
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

CBX7_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.011766 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

DUS1_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.049452 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

K0408_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.020152 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

PTN3_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.021956 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	258	Shared Neighborhood Hits	15
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

SLIT2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.003741 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	708	Shared Neighborhood Hits	3
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.003735 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	684	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CC14B_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.106316 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	103	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS8_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.054183 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

TP4A3_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.050798 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

Hits sorted by NC score

DUS11_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

DUS11_MOUSE
NC score	0.977154 (rank : 2)	θ value	3.89193e-128 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

MCE1_HUMAN
NC score	0.656453 (rank : 3)	θ value	1.5773e-20 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

MCE1_MOUSE
NC score	0.651511 (rank : 4)	θ value	1.74391e-19 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	O55236	Gene names	Rngtt, Cap1a
Domain Architecture
Description	mRNA capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

DUS23_HUMAN
NC score	0.246008 (rank : 5)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

DUS23_MOUSE
NC score	0.241904 (rank : 6)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

PTPM1_MOUSE
NC score	0.234877 (rank : 7)	θ value	0.0193708 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	64	Shared Neighborhood Hits	20
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

TPTE_HUMAN
NC score	0.207489 (rank : 8)	θ value	0.00228821 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	19
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

TPTE2_HUMAN
NC score	0.183673 (rank : 9)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

PTPM1_HUMAN
NC score	0.182446 (rank : 10)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	60	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTEN_HUMAN
NC score	0.164622 (rank : 11)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.164621 (rank : 12)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	73	Shared Neighborhood Hits	25
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

CC14B_HUMAN
NC score	0.127533 (rank : 13)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14A_HUMAN
NC score	0.120060 (rank : 14)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	133	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
NC score	0.115125 (rank : 15)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14B_MOUSE
NC score	0.106316 (rank : 16)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	103	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS2_MOUSE
NC score	0.068815 (rank : 17)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS16_HUMAN
NC score	0.066894 (rank : 18)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS2_HUMAN
NC score	0.063267 (rank : 19)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS8_MOUSE
NC score	0.054183 (rank : 20)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

PTPRJ_HUMAN
NC score	0.051221 (rank : 21)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

TP4A3_MOUSE
NC score	0.050798 (rank : 22)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

DUS1_MOUSE
NC score	0.049647 (rank : 23)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS1_HUMAN
NC score	0.049452 (rank : 24)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

PTPRJ_MOUSE
NC score	0.045319 (rank : 25)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRA_MOUSE
NC score	0.034876 (rank : 26)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRA_HUMAN
NC score	0.034481 (rank : 27)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTN14_HUMAN
NC score	0.024702 (rank : 28)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTPRD_MOUSE
NC score	0.024532 (rank : 29)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	491	Shared Neighborhood Hits	18
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_HUMAN
NC score	0.024332 (rank : 30)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	485	Shared Neighborhood Hits	18
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRS_HUMAN
NC score	0.024224 (rank : 31)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	472	Shared Neighborhood Hits	18
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTN3_HUMAN
NC score	0.021956 (rank : 32)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	258	Shared Neighborhood Hits	15
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

K0408_HUMAN
NC score	0.020152 (rank : 33)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

CBX7_HUMAN
NC score	0.011766 (rank : 34)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

AMOT_HUMAN
NC score	0.011262 (rank : 35)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	712	Shared Neighborhood Hits	3
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

BRD4_HUMAN
NC score	0.011241 (rank : 36)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	851	Shared Neighborhood Hits	3
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CASR_HUMAN
NC score	0.010070 (rank : 37)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

SLIT2_HUMAN
NC score	0.003741 (rank : 38)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	708	Shared Neighborhood Hits	3
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
NC score	0.003735 (rank : 39)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	684	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ZBT24_HUMAN
NC score	0.000785 (rank : 40)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	870	Shared Neighborhood Hits	2
SwissProt Accessions	O43167, Q5TED5, Q8N455	Gene names	ZBTB24, KIAA0441, ZNF450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450).