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Network neighborhood for query Sequence : DUS8_MOUSE

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DUS8_MOUSE
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DUS8_HUMAN
θ value	0 (rank : 1)	NC score	0.984860 (rank : 2)
Query Neighborhood Hits	119	Target Neighborhood Hits	161	Shared Neighborhood Hits	83
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS8_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	119
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS16_HUMAN
θ value	5.80223e-132 (rank : 3)	NC score	0.975594 (rank : 3)
Query Neighborhood Hits	119	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS10_HUMAN
θ value	3.72821e-46 (rank : 4)	NC score	0.930432 (rank : 6)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_MOUSE
θ value	2.41655e-45 (rank : 5)	NC score	0.931292 (rank : 5)
Query Neighborhood Hits	119	Target Neighborhood Hits	62	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS7_HUMAN
θ value	9.50281e-42 (rank : 6)	NC score	0.926026 (rank : 7)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	56
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS6_HUMAN
θ value	3.99248e-40 (rank : 7)	NC score	0.922434 (rank : 8)
Query Neighborhood Hits	119	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS1_MOUSE
θ value	8.89434e-40 (rank : 8)	NC score	0.914573 (rank : 12)
Query Neighborhood Hits	119	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS6_MOUSE
θ value	1.16164e-39 (rank : 9)	NC score	0.922032 (rank : 9)
Query Neighborhood Hits	119	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS4_MOUSE
θ value	3.37985e-39 (rank : 10)	NC score	0.913212 (rank : 15)
Query Neighborhood Hits	119	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS9_HUMAN
θ value	3.37985e-39 (rank : 11)	NC score	0.932918 (rank : 4)
Query Neighborhood Hits	119	Target Neighborhood Hits	59	Shared Neighborhood Hits	53
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS4_HUMAN
θ value	4.41421e-39 (rank : 12)	NC score	0.913939 (rank : 14)
Query Neighborhood Hits	119	Target Neighborhood Hits	77	Shared Neighborhood Hits	55
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS1_HUMAN
θ value	2.86122e-38 (rank : 13)	NC score	0.914311 (rank : 13)
Query Neighborhood Hits	119	Target Neighborhood Hits	73	Shared Neighborhood Hits	56
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS2_MOUSE
θ value	4.568e-36 (rank : 14)	NC score	0.921718 (rank : 10)
Query Neighborhood Hits	119	Target Neighborhood Hits	86	Shared Neighborhood Hits	61
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS2_HUMAN
θ value	5.96599e-36 (rank : 15)	NC score	0.921269 (rank : 11)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS5_HUMAN
θ value	1.28732e-30 (rank : 16)	NC score	0.911789 (rank : 16)
Query Neighborhood Hits	119	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

SSH3_MOUSE
θ value	2.06002e-20 (rank : 17)	NC score	0.786757 (rank : 31)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

SSH1_HUMAN
θ value	1.92812e-18 (rank : 18)	NC score	0.767827 (rank : 37)
Query Neighborhood Hits	119	Target Neighborhood Hits	164	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SSH3_HUMAN
θ value	2.5182e-18 (rank : 19)	NC score	0.782892 (rank : 32)
Query Neighborhood Hits	119	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

STYX_MOUSE
θ value	4.29542e-18 (rank : 20)	NC score	0.860156 (rank : 21)
Query Neighborhood Hits	119	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

STYX_HUMAN
θ value	5.60996e-18 (rank : 21)	NC score	0.861252 (rank : 20)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

SSH2_HUMAN
θ value	1.24977e-17 (rank : 22)	NC score	0.751755 (rank : 41)
Query Neighborhood Hits	119	Target Neighborhood Hits	140	Shared Neighborhood Hits	51
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SSH2_MOUSE
θ value	1.24977e-17 (rank : 23)	NC score	0.753891 (rank : 40)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	50
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

DUS22_HUMAN
θ value	2.13179e-17 (rank : 24)	NC score	0.865897 (rank : 18)
Query Neighborhood Hits	119	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

DUS22_MOUSE
θ value	3.63628e-17 (rank : 25)	NC score	0.866232 (rank : 17)
Query Neighborhood Hits	119	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

SSH1_MOUSE
θ value	4.74913e-17 (rank : 26)	NC score	0.767494 (rank : 38)
Query Neighborhood Hits	119	Target Neighborhood Hits	107	Shared Neighborhood Hits	52
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

DUS14_HUMAN
θ value	1.38178e-16 (rank : 27)	NC score	0.855894 (rank : 24)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS18_MOUSE
θ value	2.35696e-16 (rank : 28)	NC score	0.837548 (rank : 27)
Query Neighborhood Hits	119	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

DUS18_HUMAN
θ value	3.07829e-16 (rank : 29)	NC score	0.837538 (rank : 28)
Query Neighborhood Hits	119	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

DUS14_MOUSE
θ value	5.25075e-16 (rank : 30)	NC score	0.857234 (rank : 22)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

DUS19_HUMAN
θ value	1.99529e-15 (rank : 31)	NC score	0.862377 (rank : 19)
Query Neighborhood Hits	119	Target Neighborhood Hits	52	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS21_HUMAN
θ value	1.99529e-15 (rank : 32)	NC score	0.838108 (rank : 26)
Query Neighborhood Hits	119	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS19_MOUSE
θ value	5.8054e-15 (rank : 33)	NC score	0.856812 (rank : 23)
Query Neighborhood Hits	119	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS15_HUMAN
θ value	1.68911e-14 (rank : 34)	NC score	0.846555 (rank : 25)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS12_MOUSE
θ value	1.74796e-11 (rank : 35)	NC score	0.782819 (rank : 33)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

DUS3_HUMAN
θ value	1.133e-10 (rank : 36)	NC score	0.825534 (rank : 29)
Query Neighborhood Hits	119	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
θ value	2.52405e-10 (rank : 37)	NC score	0.824325 (rank : 30)
Query Neighborhood Hits	119	Target Neighborhood Hits	54	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

DUS12_HUMAN
θ value	5.62301e-10 (rank : 38)	NC score	0.766542 (rank : 39)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

DUS13_MOUSE
θ value	6.21693e-09 (rank : 39)	NC score	0.782199 (rank : 34)
Query Neighborhood Hits	119	Target Neighborhood Hits	56	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

DUS13_HUMAN
θ value	4.0297e-08 (rank : 40)	NC score	0.777005 (rank : 35)
Query Neighborhood Hits	119	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

OGFR_HUMAN
θ value	1.29631e-06 (rank : 41)	NC score	0.065910 (rank : 59)
Query Neighborhood Hits	119	Target Neighborhood Hits	1582	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

STYL1_HUMAN
θ value	2.88788e-06 (rank : 42)	NC score	0.772812 (rank : 36)
Query Neighborhood Hits	119	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

MUC1_HUMAN
θ value	0.00020696 (rank : 43)	NC score	0.039655 (rank : 68)
Query Neighborhood Hits	119	Target Neighborhood Hits	975	Shared Neighborhood Hits	30
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

DUS23_HUMAN
θ value	0.000270298 (rank : 44)	NC score	0.341671 (rank : 44)
Query Neighborhood Hits	119	Target Neighborhood Hits	98	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

DUS23_MOUSE
θ value	0.00102713 (rank : 45)	NC score	0.315096 (rank : 46)
Query Neighborhood Hits	119	Target Neighborhood Hits	94	Shared Neighborhood Hits	44
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

PTPM1_MOUSE
θ value	0.00134147 (rank : 46)	NC score	0.516614 (rank : 42)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	56
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

CC14B_HUMAN
θ value	0.00390308 (rank : 47)	NC score	0.319878 (rank : 45)
Query Neighborhood Hits	119	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

RGS3_MOUSE
θ value	0.00665767 (rank : 48)	NC score	0.027720 (rank : 75)
Query Neighborhood Hits	119	Target Neighborhood Hits	1621	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MAGE1_HUMAN
θ value	0.00869519 (rank : 49)	NC score	0.026239 (rank : 80)
Query Neighborhood Hits	119	Target Neighborhood Hits	1389	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PTPM1_HUMAN
θ value	0.00869519 (rank : 50)	NC score	0.479907 (rank : 43)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

NCOA6_HUMAN
θ value	0.0193708 (rank : 51)	NC score	0.045590 (rank : 66)
Query Neighborhood Hits	119	Target Neighborhood Hits	1202	Shared Neighborhood Hits	31
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CO5A2_HUMAN
θ value	0.0252991 (rank : 52)	NC score	0.026693 (rank : 78)
Query Neighborhood Hits	119	Target Neighborhood Hits	760	Shared Neighborhood Hits	27
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

NCOA6_MOUSE
θ value	0.0252991 (rank : 53)	NC score	0.049179 (rank : 65)
Query Neighborhood Hits	119	Target Neighborhood Hits	1076	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

DUS11_MOUSE
θ value	0.0330416 (rank : 54)	NC score	0.112388 (rank : 58)
Query Neighborhood Hits	119	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

CC14B_MOUSE
θ value	0.0563607 (rank : 55)	NC score	0.281833 (rank : 49)
Query Neighborhood Hits	119	Target Neighborhood Hits	103	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

K1802_MOUSE
θ value	0.0736092 (rank : 56)	NC score	0.028472 (rank : 74)
Query Neighborhood Hits	119	Target Neighborhood Hits	1596	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TP4A2_HUMAN
θ value	0.0961366 (rank : 57)	NC score	0.130017 (rank : 56)
Query Neighborhood Hits	119	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	0.0961366 (rank : 58)	NC score	0.130017 (rank : 57)
Query Neighborhood Hits	119	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

EPM2A_HUMAN
θ value	0.163984 (rank : 59)	NC score	0.282969 (rank : 48)
Query Neighborhood Hits	119	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

EPM2A_MOUSE
θ value	0.163984 (rank : 60)	NC score	0.284199 (rank : 47)
Query Neighborhood Hits	119	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

FOXE2_HUMAN
θ value	0.163984 (rank : 61)	NC score	0.014033 (rank : 100)
Query Neighborhood Hits	119	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

IASPP_MOUSE
θ value	0.163984 (rank : 62)	NC score	0.026101 (rank : 81)
Query Neighborhood Hits	119	Target Neighborhood Hits	1024	Shared Neighborhood Hits	29
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PGCA_MOUSE
θ value	0.21417 (rank : 63)	NC score	0.020088 (rank : 86)
Query Neighborhood Hits	119	Target Neighborhood Hits	643	Shared Neighborhood Hits	19
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

TP4A1_HUMAN
θ value	0.21417 (rank : 64)	NC score	0.131268 (rank : 54)
Query Neighborhood Hits	119	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	0.21417 (rank : 65)	NC score	0.131268 (rank : 55)
Query Neighborhood Hits	119	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

JPH2_HUMAN
θ value	0.279714 (rank : 66)	NC score	0.027381 (rank : 77)
Query Neighborhood Hits	119	Target Neighborhood Hits	639	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MLL3_MOUSE
θ value	0.279714 (rank : 67)	NC score	0.021802 (rank : 84)
Query Neighborhood Hits	119	Target Neighborhood Hits	1399	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SENP5_HUMAN
θ value	0.279714 (rank : 68)	NC score	0.023844 (rank : 82)
Query Neighborhood Hits	119	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

MK15_HUMAN
θ value	0.365318 (rank : 69)	NC score	0.001413 (rank : 121)
Query Neighborhood Hits	119	Target Neighborhood Hits	1038	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

TP4A3_HUMAN
θ value	0.365318 (rank : 70)	NC score	0.158243 (rank : 52)
Query Neighborhood Hits	119	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
θ value	0.365318 (rank : 71)	NC score	0.154280 (rank : 53)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

FGD3_MOUSE
θ value	0.47712 (rank : 72)	NC score	0.011326 (rank : 106)
Query Neighborhood Hits	119	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

PHLPP_HUMAN
θ value	0.47712 (rank : 73)	NC score	0.018279 (rank : 90)
Query Neighborhood Hits	119	Target Neighborhood Hits	604	Shared Neighborhood Hits	23
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

BSN_MOUSE
θ value	0.62314 (rank : 74)	NC score	0.035019 (rank : 70)
Query Neighborhood Hits	119	Target Neighborhood Hits	2057	Shared Neighborhood Hits	39
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CC14A_HUMAN
θ value	0.62314 (rank : 75)	NC score	0.257377 (rank : 51)
Query Neighborhood Hits	119	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
θ value	0.62314 (rank : 76)	NC score	0.260824 (rank : 50)
Query Neighborhood Hits	119	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

C2TA_HUMAN
θ value	0.813845 (rank : 77)	NC score	0.019436 (rank : 87)
Query Neighborhood Hits	119	Target Neighborhood Hits	190	Shared Neighborhood Hits	14
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CO002_HUMAN
θ value	0.813845 (rank : 78)	NC score	0.034605 (rank : 71)
Query Neighborhood Hits	119	Target Neighborhood Hits	387	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CTDP1_HUMAN
θ value	0.813845 (rank : 79)	NC score	0.033028 (rank : 72)
Query Neighborhood Hits	119	Target Neighborhood Hits	416	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

MUCDL_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.035784 (rank : 69)
Query Neighborhood Hits	119	Target Neighborhood Hits	777	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ITAM_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.008658 (rank : 110)
Query Neighborhood Hits	119	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

MCPH1_MOUSE
θ value	1.06291 (rank : 82)	NC score	0.020969 (rank : 85)
Query Neighborhood Hits	119	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MUCDL_MOUSE
θ value	1.06291 (rank : 83)	NC score	0.031442 (rank : 73)
Query Neighborhood Hits	119	Target Neighborhood Hits	461	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

P80C_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.026460 (rank : 79)
Query Neighborhood Hits	119	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

SNPC4_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.040012 (rank : 67)
Query Neighborhood Hits	119	Target Neighborhood Hits	589	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

AATK_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.001898 (rank : 120)
Query Neighborhood Hits	119	Target Neighborhood Hits	1243	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ICAM4_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.027399 (rank : 76)
Query Neighborhood Hits	119	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q14773, Q14771, Q14772, Q16375	Gene names	ICAM4, LW
Domain Architecture
Description	Intercellular adhesion molecule 4 precursor (ICAM-4) (Landsteiner- Wiener blood group glycoprotein) (LW blood group protein) (CD242 antigen).

P73_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.013734 (rank : 102)
Query Neighborhood Hits	119	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

CLIC6_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.012484 (rank : 104)
Query Neighborhood Hits	119	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CSKI1_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.017097 (rank : 94)
Query Neighborhood Hits	119	Target Neighborhood Hits	997	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DNMT1_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.017636 (rank : 91)
Query Neighborhood Hits	119	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

LDB3_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.017277 (rank : 93)
Query Neighborhood Hits	119	Target Neighborhood Hits	510	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

NR2E3_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.002432 (rank : 119)
Query Neighborhood Hits	119	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

DIDO1_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.018296 (rank : 89)
Query Neighborhood Hits	119	Target Neighborhood Hits	960	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MINT_MOUSE
θ value	3.0926 (rank : 95)	NC score	0.010882 (rank : 107)
Query Neighborhood Hits	119	Target Neighborhood Hits	1514	Shared Neighborhood Hits	25
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SSBP4_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.018836 (rank : 88)
Query Neighborhood Hits	119	Target Neighborhood Hits	753	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

WDFY3_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.009458 (rank : 109)
Query Neighborhood Hits	119	Target Neighborhood Hits	348	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

BCAR1_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.015296 (rank : 97)
Query Neighborhood Hits	119	Target Neighborhood Hits	438	Shared Neighborhood Hits	18
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

GDF1_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.004418 (rank : 117)
Query Neighborhood Hits	119	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	P20863	Gene names	Gdf1, Gdf-1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

SC6A5_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.006002 (rank : 115)
Query Neighborhood Hits	119	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

TCGAP_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.010537 (rank : 108)
Query Neighborhood Hits	119	Target Neighborhood Hits	872	Shared Neighborhood Hits	23
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BC11B_HUMAN
θ value	5.27518 (rank : 102)	NC score	-0.004055 (rank : 124)
Query Neighborhood Hits	119	Target Neighborhood Hits	761	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0K0, Q9H162	Gene names	BCL11B, CTIP2, RIT1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (hRit1) (COUP-TF-interacting protein 2).

CABL2_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.013648 (rank : 103)
Query Neighborhood Hits	119	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

CD248_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.005258 (rank : 116)
Query Neighborhood Hits	119	Target Neighborhood Hits	679	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ELL_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.012431 (rank : 105)
Query Neighborhood Hits	119	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

MEGF9_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.007166 (rank : 114)
Query Neighborhood Hits	119	Target Neighborhood Hits	896	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PTPRE_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.017476 (rank : 92)
Query Neighborhood Hits	119	Target Neighborhood Hits	92	Shared Neighborhood Hits	23
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

SPEG_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.001312 (rank : 122)
Query Neighborhood Hits	119	Target Neighborhood Hits	1959	Shared Neighborhood Hits	33
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MLL3_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.021807 (rank : 83)
Query Neighborhood Hits	119	Target Neighborhood Hits	1644	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PF21B_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.014894 (rank : 99)
Query Neighborhood Hits	119	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PKD1_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.007702 (rank : 113)
Query Neighborhood Hits	119	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

PTPRE_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.013777 (rank : 101)
Query Neighborhood Hits	119	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

CB024_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.008096 (rank : 112)
Query Neighborhood Hits	119	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K158, Q3TE87	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf24 homolog.

CDX4_HUMAN
θ value	8.99809 (rank : 114)	NC score	-0.001330 (rank : 123)
Query Neighborhood Hits	119	Target Neighborhood Hits	366	Shared Neighborhood Hits	3
SwissProt Accessions	O14627, Q5JS20	Gene names	CDX4
Domain Architecture
Description	Homeobox protein CDX-4 (Caudal-type homeobox protein 4).

CEBPE_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.004340 (rank : 118)
Query Neighborhood Hits	119	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CF015_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.015642 (rank : 96)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

NOL3_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.015048 (rank : 98)
Query Neighborhood Hits	119	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

PKHA6_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.008309 (rank : 111)
Query Neighborhood Hits	119	Target Neighborhood Hits	556	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PTPRA_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.015744 (rank : 95)
Query Neighborhood Hits	119	Target Neighborhood Hits	93	Shared Neighborhood Hits	20
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

DUS11_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.054183 (rank : 63)
Query Neighborhood Hits	119	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

PRB3_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.055447 (rank : 62)
Query Neighborhood Hits	119	Target Neighborhood Hits	318	Shared Neighborhood Hits	29
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.051168 (rank : 64)
Query Neighborhood Hits	119	Target Neighborhood Hits	330	Shared Neighborhood Hits	27
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.056999 (rank : 61)
Query Neighborhood Hits	119	Target Neighborhood Hits	385	Shared Neighborhood Hits	29
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.059359 (rank : 60)
Query Neighborhood Hits	119	Target Neighborhood Hits	347	Shared Neighborhood Hits	28
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

Hits sorted by NC score

DUS8_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	119
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS8_HUMAN
NC score	0.984860 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	119	Target Neighborhood Hits	161	Shared Neighborhood Hits	83
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS16_HUMAN
NC score	0.975594 (rank : 3)	θ value	5.80223e-132 (rank : 3)
Query Neighborhood Hits	119	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS9_HUMAN
NC score	0.932918 (rank : 4)	θ value	3.37985e-39 (rank : 11)
Query Neighborhood Hits	119	Target Neighborhood Hits	59	Shared Neighborhood Hits	53
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS10_MOUSE
NC score	0.931292 (rank : 5)	θ value	2.41655e-45 (rank : 5)
Query Neighborhood Hits	119	Target Neighborhood Hits	62	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_HUMAN
NC score	0.930432 (rank : 6)	θ value	3.72821e-46 (rank : 4)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS7_HUMAN
NC score	0.926026 (rank : 7)	θ value	9.50281e-42 (rank : 6)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	56
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS6_HUMAN
NC score	0.922434 (rank : 8)	θ value	3.99248e-40 (rank : 7)
Query Neighborhood Hits	119	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS6_MOUSE
NC score	0.922032 (rank : 9)	θ value	1.16164e-39 (rank : 9)
Query Neighborhood Hits	119	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS2_MOUSE
NC score	0.921718 (rank : 10)	θ value	4.568e-36 (rank : 14)
Query Neighborhood Hits	119	Target Neighborhood Hits	86	Shared Neighborhood Hits	61
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS2_HUMAN
NC score	0.921269 (rank : 11)	θ value	5.96599e-36 (rank : 15)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS1_MOUSE
NC score	0.914573 (rank : 12)	θ value	8.89434e-40 (rank : 8)
Query Neighborhood Hits	119	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS1_HUMAN
NC score	0.914311 (rank : 13)	θ value	2.86122e-38 (rank : 13)
Query Neighborhood Hits	119	Target Neighborhood Hits	73	Shared Neighborhood Hits	56
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS4_HUMAN
NC score	0.913939 (rank : 14)	θ value	4.41421e-39 (rank : 12)
Query Neighborhood Hits	119	Target Neighborhood Hits	77	Shared Neighborhood Hits	55
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS4_MOUSE
NC score	0.913212 (rank : 15)	θ value	3.37985e-39 (rank : 10)
Query Neighborhood Hits	119	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS5_HUMAN
NC score	0.911789 (rank : 16)	θ value	1.28732e-30 (rank : 16)
Query Neighborhood Hits	119	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS22_MOUSE
NC score	0.866232 (rank : 17)	θ value	3.63628e-17 (rank : 25)
Query Neighborhood Hits	119	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

DUS22_HUMAN
NC score	0.865897 (rank : 18)	θ value	2.13179e-17 (rank : 24)
Query Neighborhood Hits	119	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

DUS19_HUMAN
NC score	0.862377 (rank : 19)	θ value	1.99529e-15 (rank : 31)
Query Neighborhood Hits	119	Target Neighborhood Hits	52	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

STYX_HUMAN
NC score	0.861252 (rank : 20)	θ value	5.60996e-18 (rank : 21)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

STYX_MOUSE
NC score	0.860156 (rank : 21)	θ value	4.29542e-18 (rank : 20)
Query Neighborhood Hits	119	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

DUS14_MOUSE
NC score	0.857234 (rank : 22)	θ value	5.25075e-16 (rank : 30)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

DUS19_MOUSE
NC score	0.856812 (rank : 23)	θ value	5.8054e-15 (rank : 33)
Query Neighborhood Hits	119	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS14_HUMAN
NC score	0.855894 (rank : 24)	θ value	1.38178e-16 (rank : 27)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS15_HUMAN
NC score	0.846555 (rank : 25)	θ value	1.68911e-14 (rank : 34)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS21_HUMAN
NC score	0.838108 (rank : 26)	θ value	1.99529e-15 (rank : 32)
Query Neighborhood Hits	119	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS18_MOUSE
NC score	0.837548 (rank : 27)	θ value	2.35696e-16 (rank : 28)
Query Neighborhood Hits	119	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

DUS18_HUMAN
NC score	0.837538 (rank : 28)	θ value	3.07829e-16 (rank : 29)
Query Neighborhood Hits	119	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

DUS3_HUMAN
NC score	0.825534 (rank : 29)	θ value	1.133e-10 (rank : 36)
Query Neighborhood Hits	119	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
NC score	0.824325 (rank : 30)	θ value	2.52405e-10 (rank : 37)
Query Neighborhood Hits	119	Target Neighborhood Hits	54	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

SSH3_MOUSE
NC score	0.786757 (rank : 31)	θ value	2.06002e-20 (rank : 17)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

SSH3_HUMAN
NC score	0.782892 (rank : 32)	θ value	2.5182e-18 (rank : 19)
Query Neighborhood Hits	119	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

DUS12_MOUSE
NC score	0.782819 (rank : 33)	θ value	1.74796e-11 (rank : 35)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

DUS13_MOUSE
NC score	0.782199 (rank : 34)	θ value	6.21693e-09 (rank : 39)
Query Neighborhood Hits	119	Target Neighborhood Hits	56	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

DUS13_HUMAN
NC score	0.777005 (rank : 35)	θ value	4.0297e-08 (rank : 40)
Query Neighborhood Hits	119	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

STYL1_HUMAN
NC score	0.772812 (rank : 36)	θ value	2.88788e-06 (rank : 42)
Query Neighborhood Hits	119	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

SSH1_HUMAN
NC score	0.767827 (rank : 37)	θ value	1.92812e-18 (rank : 18)
Query Neighborhood Hits	119	Target Neighborhood Hits	164	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SSH1_MOUSE
NC score	0.767494 (rank : 38)	θ value	4.74913e-17 (rank : 26)
Query Neighborhood Hits	119	Target Neighborhood Hits	107	Shared Neighborhood Hits	52
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

DUS12_HUMAN
NC score	0.766542 (rank : 39)	θ value	5.62301e-10 (rank : 38)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

SSH2_MOUSE
NC score	0.753891 (rank : 40)	θ value	1.24977e-17 (rank : 23)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	50
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

SSH2_HUMAN
NC score	0.751755 (rank : 41)	θ value	1.24977e-17 (rank : 22)
Query Neighborhood Hits	119	Target Neighborhood Hits	140	Shared Neighborhood Hits	51
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

PTPM1_MOUSE
NC score	0.516614 (rank : 42)	θ value	0.00134147 (rank : 46)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	56
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTPM1_HUMAN
NC score	0.479907 (rank : 43)	θ value	0.00869519 (rank : 50)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

DUS23_HUMAN
NC score	0.341671 (rank : 44)	θ value	0.000270298 (rank : 44)
Query Neighborhood Hits	119	Target Neighborhood Hits	98	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

CC14B_HUMAN
NC score	0.319878 (rank : 45)	θ value	0.00390308 (rank : 47)
Query Neighborhood Hits	119	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS23_MOUSE
NC score	0.315096 (rank : 46)	θ value	0.00102713 (rank : 45)
Query Neighborhood Hits	119	Target Neighborhood Hits	94	Shared Neighborhood Hits	44
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

EPM2A_MOUSE
NC score	0.284199 (rank : 47)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	119	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

EPM2A_HUMAN
NC score	0.282969 (rank : 48)	θ value	0.163984 (rank : 59)
Query Neighborhood Hits	119	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

CC14B_MOUSE
NC score	0.281833 (rank : 49)	θ value	0.0563607 (rank : 55)
Query Neighborhood Hits	119	Target Neighborhood Hits	103	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14A_MOUSE
NC score	0.260824 (rank : 50)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	119	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_HUMAN
NC score	0.257377 (rank : 51)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	119	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

TP4A3_HUMAN
NC score	0.158243 (rank : 52)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	119	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
NC score	0.154280 (rank : 53)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

TP4A1_HUMAN
NC score	0.131268 (rank : 54)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	119	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.131268 (rank : 55)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	119	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TP4A2_HUMAN
NC score	0.130017 (rank : 56)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	119	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.130017 (rank : 57)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	119	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

DUS11_MOUSE
NC score	0.112388 (rank : 58)	θ value	0.0330416 (rank : 54)
Query Neighborhood Hits	119	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

OGFR_HUMAN
NC score	0.065910 (rank : 59)	θ value	1.29631e-06 (rank : 41)
Query Neighborhood Hits	119	Target Neighborhood Hits	1582	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRP2_MOUSE
NC score	0.059359 (rank : 60)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	119	Target Neighborhood Hits	347	Shared Neighborhood Hits	28
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP1_HUMAN
NC score	0.056999 (rank : 61)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	119	Target Neighborhood Hits	385	Shared Neighborhood Hits	29
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRB3_HUMAN
NC score	0.055447 (rank : 62)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	119	Target Neighborhood Hits	318	Shared Neighborhood Hits	29
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

DUS11_HUMAN
NC score	0.054183 (rank : 63)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	119	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

PRB4S_HUMAN
NC score	0.051168 (rank : 64)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	119	Target Neighborhood Hits	330	Shared Neighborhood Hits	27
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

NCOA6_MOUSE
NC score	0.049179 (rank : 65)	θ value	0.0252991 (rank : 53)
Query Neighborhood Hits	119	Target Neighborhood Hits	1076	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOA6_HUMAN
NC score	0.045590 (rank : 66)	θ value	0.0193708 (rank : 51)
Query Neighborhood Hits	119	Target Neighborhood Hits	1202	Shared Neighborhood Hits	31
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SNPC4_HUMAN
NC score	0.040012 (rank : 67)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	119	Target Neighborhood Hits	589	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

MUC1_HUMAN
NC score	0.039655 (rank : 68)	θ value	0.00020696 (rank : 43)
Query Neighborhood Hits	119	Target Neighborhood Hits	975	Shared Neighborhood Hits	30
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUCDL_HUMAN
NC score	0.035784 (rank : 69)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	119	Target Neighborhood Hits	777	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

BSN_MOUSE
NC score	0.035019 (rank : 70)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	119	Target Neighborhood Hits	2057	Shared Neighborhood Hits	39
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CO002_HUMAN
NC score	0.034605 (rank : 71)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	119	Target Neighborhood Hits	387	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CTDP1_HUMAN
NC score	0.033028 (rank : 72)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	119	Target Neighborhood Hits	416	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

MUCDL_MOUSE
NC score	0.031442 (rank : 73)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	119	Target Neighborhood Hits	461	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

K1802_MOUSE
NC score	0.028472 (rank : 74)	θ value	0.0736092 (rank : 56)
Query Neighborhood Hits	119	Target Neighborhood Hits	1596	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RGS3_MOUSE
NC score	0.027720 (rank : 75)	θ value	0.00665767 (rank : 48)
Query Neighborhood Hits	119	Target Neighborhood Hits	1621	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ICAM4_HUMAN
NC score	0.027399 (rank : 76)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	119	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q14773, Q14771, Q14772, Q16375	Gene names	ICAM4, LW
Domain Architecture
Description	Intercellular adhesion molecule 4 precursor (ICAM-4) (Landsteiner- Wiener blood group glycoprotein) (LW blood group protein) (CD242 antigen).

JPH2_HUMAN
NC score	0.027381 (rank : 77)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	119	Target Neighborhood Hits	639	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CO5A2_HUMAN
NC score	0.026693 (rank : 78)	θ value	0.0252991 (rank : 52)
Query Neighborhood Hits	119	Target Neighborhood Hits	760	Shared Neighborhood Hits	27
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

P80C_HUMAN
NC score	0.026460 (rank : 79)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	119	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

MAGE1_HUMAN
NC score	0.026239 (rank : 80)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	119	Target Neighborhood Hits	1389	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

IASPP_MOUSE
NC score	0.026101 (rank : 81)	θ value	0.163984 (rank : 62)
Query Neighborhood Hits	119	Target Neighborhood Hits	1024	Shared Neighborhood Hits	29
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SENP5_HUMAN
NC score	0.023844 (rank : 82)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	119	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

MLL3_HUMAN
NC score	0.021807 (rank : 83)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	119	Target Neighborhood Hits	1644	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
NC score	0.021802 (rank : 84)	θ value	0.279714 (rank : 67)
Query Neighborhood Hits	119	Target Neighborhood Hits	1399	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MCPH1_MOUSE
NC score	0.020969 (rank : 85)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	119	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

PGCA_MOUSE
NC score	0.020088 (rank : 86)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	119	Target Neighborhood Hits	643	Shared Neighborhood Hits	19
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

C2TA_HUMAN
NC score	0.019436 (rank : 87)	θ value	0.813845 (rank : 77)
Query Neighborhood Hits	119	Target Neighborhood Hits	190	Shared Neighborhood Hits	14
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

SSBP4_HUMAN
NC score	0.018836 (rank : 88)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	119	Target Neighborhood Hits	753	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

DIDO1_HUMAN
NC score	0.018296 (rank : 89)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	119	Target Neighborhood Hits	960	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

PHLPP_HUMAN
NC score	0.018279 (rank : 90)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	119	Target Neighborhood Hits	604	Shared Neighborhood Hits	23
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

DNMT1_MOUSE
NC score	0.017636 (rank : 91)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	119	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

PTPRE_HUMAN
NC score	0.017476 (rank : 92)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	119	Target Neighborhood Hits	92	Shared Neighborhood Hits	23
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

LDB3_MOUSE
NC score	0.017277 (rank : 93)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	119	Target Neighborhood Hits	510	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

CSKI1_HUMAN
NC score	0.017097 (rank : 94)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	119	Target Neighborhood Hits	997	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PTPRA_MOUSE
NC score	0.015744 (rank : 95)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	119	Target Neighborhood Hits	93	Shared Neighborhood Hits	20
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

CF015_HUMAN
NC score	0.015642 (rank : 96)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	119	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

BCAR1_MOUSE
NC score	0.015296 (rank : 97)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	119	Target Neighborhood Hits	438	Shared Neighborhood Hits	18
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

NOL3_MOUSE
NC score	0.015048 (rank : 98)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	119	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

PF21B_HUMAN
NC score	0.014894 (rank : 99)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	119	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

FOXE2_HUMAN
NC score	0.014033 (rank : 100)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	119	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

PTPRE_MOUSE
NC score	0.013777 (rank : 101)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	119	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

P73_HUMAN
NC score	0.013734 (rank : 102)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	119	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

CABL2_HUMAN
NC score	0.013648 (rank : 103)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	119	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

CLIC6_HUMAN
NC score	0.012484 (rank : 104)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	119	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

ELL_MOUSE
NC score	0.012431 (rank : 105)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	119	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

FGD3_MOUSE
NC score	0.011326 (rank : 106)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	119	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

MINT_MOUSE
NC score	0.010882 (rank : 107)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	119	Target Neighborhood Hits	1514	Shared Neighborhood Hits	25
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TCGAP_HUMAN
NC score	0.010537 (rank : 108)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	119	Target Neighborhood Hits	872	Shared Neighborhood Hits	23
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

WDFY3_HUMAN
NC score	0.009458 (rank : 109)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	119	Target Neighborhood Hits	348	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

ITAM_HUMAN
NC score	0.008658 (rank : 110)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	119	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

PKHA6_HUMAN
NC score	0.008309 (rank : 111)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	119	Target Neighborhood Hits	556	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CB024_MOUSE
NC score	0.008096 (rank : 112)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	119	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K158, Q3TE87	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf24 homolog.

PKD1_HUMAN
NC score	0.007702 (rank : 113)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	119	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

MEGF9_MOUSE
NC score	0.007166 (rank : 114)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	119	Target Neighborhood Hits	896	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SC6A5_MOUSE
NC score	0.006002 (rank : 115)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	119	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

CD248_HUMAN
NC score	0.005258 (rank : 116)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	119	Target Neighborhood Hits	679	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GDF1_MOUSE
NC score	0.004418 (rank : 117)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	119	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	P20863	Gene names	Gdf1, Gdf-1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

CEBPE_HUMAN
NC score	0.004340 (rank : 118)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	119	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

NR2E3_MOUSE
NC score	0.002432 (rank : 119)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	119	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

AATK_HUMAN
NC score	0.001898 (rank : 120)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	119	Target Neighborhood Hits	1243	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

MK15_HUMAN
NC score	0.001413 (rank : 121)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	119	Target Neighborhood Hits	1038	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

SPEG_MOUSE
NC score	0.001312 (rank : 122)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	119	Target Neighborhood Hits	1959	Shared Neighborhood Hits	33
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CDX4_HUMAN
NC score	-0.001330 (rank : 123)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	119	Target Neighborhood Hits	366	Shared Neighborhood Hits	3
SwissProt Accessions	O14627, Q5JS20	Gene names	CDX4
Domain Architecture
Description	Homeobox protein CDX-4 (Caudal-type homeobox protein 4).

BC11B_HUMAN
NC score	-0.004055 (rank : 124)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	119	Target Neighborhood Hits	761	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0K0, Q9H162	Gene names	BCL11B, CTIP2, RIT1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (hRit1) (COUP-TF-interacting protein 2).