Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : IASPP_MOUSE

For an explanation of this page, click here

IASPP_MOUSE
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IASPP_HUMAN
θ value	0 (rank : 1)	NC score	0.886219 (rank : 2)
Query Neighborhood Hits	1024	Target Neighborhood Hits	688	Shared Neighborhood Hits	548
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IASPP_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1024	Shared Neighborhood Hits	1024
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ASPP1_MOUSE
θ value	1.65806e-78 (rank : 3)	NC score	0.767951 (rank : 3)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1244	Shared Neighborhood Hits	567
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_HUMAN
θ value	2.92676e-75 (rank : 4)	NC score	0.756809 (rank : 4)
Query Neighborhood Hits	1024	Target Neighborhood Hits	956	Shared Neighborhood Hits	453
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	2.3998e-69 (rank : 5)	NC score	0.716428 (rank : 5)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1156	Shared Neighborhood Hits	481
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

PP16B_HUMAN
θ value	3.40345e-15 (rank : 6)	NC score	0.608846 (rank : 7)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	256
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

PP16A_HUMAN
θ value	1.68911e-14 (rank : 7)	NC score	0.610104 (rank : 6)
Query Neighborhood Hits	1024	Target Neighborhood Hits	340	Shared Neighborhood Hits	270
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PP16B_MOUSE
θ value	1.68911e-14 (rank : 8)	NC score	0.608026 (rank : 8)
Query Neighborhood Hits	1024	Target Neighborhood Hits	302	Shared Neighborhood Hits	254
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

MYPT2_HUMAN
θ value	3.76295e-14 (rank : 9)	NC score	0.584110 (rank : 15)
Query Neighborhood Hits	1024	Target Neighborhood Hits	707	Shared Neighborhood Hits	272
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PP16A_MOUSE
θ value	8.38298e-14 (rank : 10)	NC score	0.603124 (rank : 9)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	259
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

MYPT1_HUMAN
θ value	1.09485e-13 (rank : 11)	NC score	0.579548 (rank : 16)
Query Neighborhood Hits	1024	Target Neighborhood Hits	723	Shared Neighborhood Hits	279
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT1_MOUSE
θ value	1.09485e-13 (rank : 12)	NC score	0.593761 (rank : 10)
Query Neighborhood Hits	1024	Target Neighborhood Hits	539	Shared Neighborhood Hits	276
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANR39_MOUSE
θ value	4.59992e-12 (rank : 13)	NC score	0.588596 (rank : 11)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	249
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_HUMAN
θ value	6.00763e-12 (rank : 14)	NC score	0.587926 (rank : 12)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	251
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR52_MOUSE
θ value	3.64472e-09 (rank : 15)	NC score	0.536675 (rank : 32)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
θ value	4.76016e-09 (rank : 16)	NC score	0.535511 (rank : 36)
Query Neighborhood Hits	1024	Target Neighborhood Hits	322	Shared Neighborhood Hits	258
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR49_MOUSE
θ value	6.21693e-09 (rank : 17)	NC score	0.584591 (rank : 13)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	250
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANK3_HUMAN
θ value	8.11959e-09 (rank : 18)	NC score	0.534695 (rank : 39)
Query Neighborhood Hits	1024	Target Neighborhood Hits	853	Shared Neighborhood Hits	327
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR49_HUMAN
θ value	8.11959e-09 (rank : 19)	NC score	0.584259 (rank : 14)
Query Neighborhood Hits	1024	Target Neighborhood Hits	282	Shared Neighborhood Hits	251
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

PRB3_HUMAN
θ value	8.11959e-09 (rank : 20)	NC score	0.196570 (rank : 387)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	130
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

TNKS2_HUMAN
θ value	1.38499e-08 (rank : 21)	NC score	0.546450 (rank : 28)
Query Neighborhood Hits	1024	Target Neighborhood Hits	361	Shared Neighborhood Hits	260
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR44_HUMAN
θ value	3.08544e-08 (rank : 22)	NC score	0.535862 (rank : 35)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

PRP2_MOUSE
θ value	4.0297e-08 (rank : 23)	NC score	0.217917 (rank : 357)
Query Neighborhood Hits	1024	Target Neighborhood Hits	347	Shared Neighborhood Hits	149
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PSD10_MOUSE
θ value	4.0297e-08 (rank : 24)	NC score	0.566375 (rank : 19)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

BCAR1_MOUSE
θ value	5.26297e-08 (rank : 25)	NC score	0.361344 (rank : 211)
Query Neighborhood Hits	1024	Target Neighborhood Hits	438	Shared Neighborhood Hits	276
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MUC1_HUMAN
θ value	5.26297e-08 (rank : 26)	NC score	0.322273 (rank : 235)
Query Neighborhood Hits	1024	Target Neighborhood Hits	975	Shared Neighborhood Hits	369
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ANK1_HUMAN
θ value	6.87365e-08 (rank : 27)	NC score	0.534826 (rank : 38)
Query Neighborhood Hits	1024	Target Neighborhood Hits	416	Shared Neighborhood Hits	264
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANKR5_MOUSE
θ value	6.87365e-08 (rank : 28)	NC score	0.556414 (rank : 24)
Query Neighborhood Hits	1024	Target Neighborhood Hits	298	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR28_MOUSE
θ value	6.87365e-08 (rank : 29)	NC score	0.536523 (rank : 33)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	258
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

TNKS1_HUMAN
θ value	8.97725e-08 (rank : 30)	NC score	0.553081 (rank : 25)
Query Neighborhood Hits	1024	Target Neighborhood Hits	477	Shared Neighborhood Hits	296
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANK2_HUMAN
θ value	1.17247e-07 (rank : 31)	NC score	0.553011 (rank : 26)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1615	Shared Neighborhood Hits	538
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PSD10_HUMAN
θ value	1.17247e-07 (rank : 32)	NC score	0.565313 (rank : 21)
Query Neighborhood Hits	1024	Target Neighborhood Hits	301	Shared Neighborhood Hits	258
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

BCAR1_HUMAN
θ value	1.53129e-07 (rank : 33)	NC score	0.370331 (rank : 203)
Query Neighborhood Hits	1024	Target Neighborhood Hits	554	Shared Neighborhood Hits	324
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

ANKR5_HUMAN
θ value	1.99992e-07 (rank : 34)	NC score	0.556484 (rank : 23)
Query Neighborhood Hits	1024	Target Neighborhood Hits	297	Shared Neighborhood Hits	253
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR29_HUMAN
θ value	2.61198e-07 (rank : 35)	NC score	0.548550 (rank : 27)
Query Neighborhood Hits	1024	Target Neighborhood Hits	294	Shared Neighborhood Hits	254
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANK1_MOUSE
θ value	3.41135e-07 (rank : 36)	NC score	0.533409 (rank : 41)
Query Neighborhood Hits	1024	Target Neighborhood Hits	430	Shared Neighborhood Hits	272
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANR50_HUMAN
θ value	4.45536e-07 (rank : 37)	NC score	0.538972 (rank : 29)
Query Neighborhood Hits	1024	Target Neighborhood Hits	361	Shared Neighborhood Hits	260
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

BARD1_MOUSE
θ value	5.81887e-07 (rank : 38)	NC score	0.528251 (rank : 50)
Query Neighborhood Hits	1024	Target Neighborhood Hits	411	Shared Neighborhood Hits	253
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANKS3_MOUSE
θ value	7.59969e-07 (rank : 39)	NC score	0.532453 (rank : 44)
Query Neighborhood Hits	1024	Target Neighborhood Hits	355	Shared Neighborhood Hits	255
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR28_HUMAN
θ value	7.59969e-07 (rank : 40)	NC score	0.533547 (rank : 40)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	258
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

CO1A1_HUMAN
θ value	7.59969e-07 (rank : 41)	NC score	0.206427 (rank : 372)
Query Neighborhood Hits	1024	Target Neighborhood Hits	475	Shared Neighborhood Hits	164
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

EHMT2_HUMAN
θ value	7.59969e-07 (rank : 42)	NC score	0.502162 (rank : 99)
Query Neighborhood Hits	1024	Target Neighborhood Hits	498	Shared Neighborhood Hits	283
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

TAF4_HUMAN
θ value	7.59969e-07 (rank : 43)	NC score	0.186000 (rank : 412)
Query Neighborhood Hits	1024	Target Neighborhood Hits	687	Shared Neighborhood Hits	188
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ANKS6_MOUSE
θ value	9.92553e-07 (rank : 44)	NC score	0.531951 (rank : 47)
Query Neighborhood Hits	1024	Target Neighborhood Hits	435	Shared Neighborhood Hits	280
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR10_MOUSE
θ value	1.29631e-06 (rank : 45)	NC score	0.530813 (rank : 48)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	243
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

EFS_HUMAN
θ value	1.69304e-06 (rank : 46)	NC score	0.326306 (rank : 233)
Query Neighborhood Hits	1024	Target Neighborhood Hits	348	Shared Neighborhood Hits	210
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	1.69304e-06 (rank : 47)	NC score	0.343998 (rank : 227)
Query Neighborhood Hits	1024	Target Neighborhood Hits	389	Shared Neighborhood Hits	234
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ITSN1_HUMAN
θ value	1.69304e-06 (rank : 48)	NC score	0.225976 (rank : 346)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1757	Shared Neighborhood Hits	322
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NFKB1_MOUSE
θ value	2.21117e-06 (rank : 49)	NC score	0.454715 (rank : 159)
Query Neighborhood Hits	1024	Target Neighborhood Hits	300	Shared Neighborhood Hits	253
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

CO1A1_MOUSE
θ value	2.88788e-06 (rank : 50)	NC score	0.201799 (rank : 378)
Query Neighborhood Hits	1024	Target Neighborhood Hits	457	Shared Neighborhood Hits	162
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

EHMT2_MOUSE
θ value	2.88788e-06 (rank : 51)	NC score	0.527167 (rank : 52)
Query Neighborhood Hits	1024	Target Neighborhood Hits	750	Shared Neighborhood Hits	416
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANKK1_HUMAN
θ value	3.77169e-06 (rank : 52)	NC score	0.377776 (rank : 194)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1075	Shared Neighborhood Hits	318
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANR10_HUMAN
θ value	3.77169e-06 (rank : 53)	NC score	0.532295 (rank : 45)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

CT032_HUMAN
θ value	3.77169e-06 (rank : 54)	NC score	0.327799 (rank : 230)
Query Neighborhood Hits	1024	Target Neighborhood Hits	235	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

ANKS3_HUMAN
θ value	4.92598e-06 (rank : 55)	NC score	0.532076 (rank : 46)
Query Neighborhood Hits	1024	Target Neighborhood Hits	355	Shared Neighborhood Hits	255
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

DGKK_HUMAN
θ value	4.92598e-06 (rank : 56)	NC score	0.118505 (rank : 602)
Query Neighborhood Hits	1024	Target Neighborhood Hits	378	Shared Neighborhood Hits	101
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

ITSN2_HUMAN
θ value	4.92598e-06 (rank : 57)	NC score	0.225709 (rank : 348)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1173	Shared Neighborhood Hits	222
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

NACAM_MOUSE
θ value	4.92598e-06 (rank : 58)	NC score	0.238736 (rank : 334)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1866	Shared Neighborhood Hits	451
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ANKS6_HUMAN
θ value	6.43352e-06 (rank : 59)	NC score	0.525928 (rank : 54)
Query Neighborhood Hits	1024	Target Neighborhood Hits	411	Shared Neighborhood Hits	281
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANKR1_HUMAN
θ value	1.09739e-05 (rank : 60)	NC score	0.533050 (rank : 42)
Query Neighborhood Hits	1024	Target Neighborhood Hits	308	Shared Neighborhood Hits	255
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANR12_HUMAN
θ value	1.09739e-05 (rank : 61)	NC score	0.471421 (rank : 138)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1081	Shared Neighborhood Hits	298
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ITSN1_MOUSE
θ value	1.09739e-05 (rank : 62)	NC score	0.223843 (rank : 353)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1669	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MTPN_MOUSE
θ value	1.09739e-05 (rank : 63)	NC score	0.565260 (rank : 22)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	246
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

PTK6_HUMAN
θ value	1.09739e-05 (rank : 64)	NC score	0.112588 (rank : 627)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1020	Shared Neighborhood Hits	183
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

ANKR1_MOUSE
θ value	1.43324e-05 (rank : 65)	NC score	0.530597 (rank : 49)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	253
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

CO4A3_HUMAN
θ value	1.43324e-05 (rank : 66)	NC score	0.189455 (rank : 403)
Query Neighborhood Hits	1024	Target Neighborhood Hits	421	Shared Neighborhood Hits	157
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

PRB4S_HUMAN
θ value	1.43324e-05 (rank : 67)	NC score	0.188117 (rank : 407)
Query Neighborhood Hits	1024	Target Neighborhood Hits	330	Shared Neighborhood Hits	138
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

WBP11_HUMAN
θ value	1.43324e-05 (rank : 68)	NC score	0.167598 (rank : 459)
Query Neighborhood Hits	1024	Target Neighborhood Hits	354	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

GRB2_HUMAN
θ value	1.87187e-05 (rank : 69)	NC score	0.315074 (rank : 244)
Query Neighborhood Hits	1024	Target Neighborhood Hits	310	Shared Neighborhood Hits	171
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	1.87187e-05 (rank : 70)	NC score	0.315057 (rank : 245)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	171
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

MTPN_HUMAN
θ value	1.87187e-05 (rank : 71)	NC score	0.566373 (rank : 20)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	246
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

PRP1_HUMAN
θ value	1.87187e-05 (rank : 72)	NC score	0.191818 (rank : 398)
Query Neighborhood Hits	1024	Target Neighborhood Hits	385	Shared Neighborhood Hits	158
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

WBP11_MOUSE
θ value	1.87187e-05 (rank : 73)	NC score	0.176619 (rank : 437)
Query Neighborhood Hits	1024	Target Neighborhood Hits	362	Shared Neighborhood Hits	138
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ASB2_HUMAN
θ value	2.44474e-05 (rank : 74)	NC score	0.518452 (rank : 67)
Query Neighborhood Hits	1024	Target Neighborhood Hits	309	Shared Neighborhood Hits	256
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CASL_HUMAN
θ value	2.44474e-05 (rank : 75)	NC score	0.292560 (rank : 266)
Query Neighborhood Hits	1024	Target Neighborhood Hits	259	Shared Neighborhood Hits	162
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	2.44474e-05 (rank : 76)	NC score	0.294247 (rank : 263)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	154
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

ANM2_HUMAN
θ value	3.19293e-05 (rank : 77)	NC score	0.213729 (rank : 361)
Query Neighborhood Hits	1024	Target Neighborhood Hits	175	Shared Neighborhood Hits	134
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

SRRM1_MOUSE
θ value	3.19293e-05 (rank : 78)	NC score	0.211231 (rank : 366)
Query Neighborhood Hits	1024	Target Neighborhood Hits	966	Shared Neighborhood Hits	275
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

AHI1_HUMAN
θ value	4.1701e-05 (rank : 79)	NC score	0.239837 (rank : 333)
Query Neighborhood Hits	1024	Target Neighborhood Hits	537	Shared Neighborhood Hits	174
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ANR11_HUMAN
θ value	4.1701e-05 (rank : 80)	NC score	0.506423 (rank : 92)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1289	Shared Neighborhood Hits	424
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR35_HUMAN
θ value	4.1701e-05 (rank : 81)	NC score	0.472359 (rank : 137)
Query Neighborhood Hits	1024	Target Neighborhood Hits	784	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

CO2A1_HUMAN
θ value	4.1701e-05 (rank : 82)	NC score	0.197714 (rank : 385)
Query Neighborhood Hits	1024	Target Neighborhood Hits	486	Shared Neighborhood Hits	179
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

ITSN2_MOUSE
θ value	4.1701e-05 (rank : 83)	NC score	0.214795 (rank : 360)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1371	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

PTK6_MOUSE
θ value	4.1701e-05 (rank : 84)	NC score	0.112340 (rank : 630)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1026	Shared Neighborhood Hits	180
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

BARD1_HUMAN
θ value	5.44631e-05 (rank : 85)	NC score	0.522693 (rank : 59)
Query Neighborhood Hits	1024	Target Neighborhood Hits	427	Shared Neighborhood Hits	258
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

GRAP_MOUSE
θ value	5.44631e-05 (rank : 86)	NC score	0.314491 (rank : 246)
Query Neighborhood Hits	1024	Target Neighborhood Hits	309	Shared Neighborhood Hits	175
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

ANKK1_MOUSE
θ value	7.1131e-05 (rank : 87)	NC score	0.368181 (rank : 205)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1072	Shared Neighborhood Hits	316
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

CSKI1_HUMAN
θ value	7.1131e-05 (rank : 88)	NC score	0.537621 (rank : 31)
Query Neighborhood Hits	1024	Target Neighborhood Hits	997	Shared Neighborhood Hits	512
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NFKB1_HUMAN
θ value	7.1131e-05 (rank : 89)	NC score	0.443038 (rank : 168)
Query Neighborhood Hits	1024	Target Neighborhood Hits	306	Shared Neighborhood Hits	254
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANM2_MOUSE
θ value	9.29e-05 (rank : 90)	NC score	0.207771 (rank : 371)
Query Neighborhood Hits	1024	Target Neighborhood Hits	175	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

CO5A2_HUMAN
θ value	9.29e-05 (rank : 91)	NC score	0.221590 (rank : 355)
Query Neighborhood Hits	1024	Target Neighborhood Hits	760	Shared Neighborhood Hits	250
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

FGR_MOUSE
θ value	9.29e-05 (rank : 92)	NC score	0.133122 (rank : 549)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1069	Shared Neighborhood Hits	204
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

GRAP_HUMAN
θ value	9.29e-05 (rank : 93)	NC score	0.311734 (rank : 249)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	177
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

TNI3K_MOUSE
θ value	9.29e-05 (rank : 94)	NC score	0.303161 (rank : 257)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1079	Shared Neighborhood Hits	317
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

AHI1_MOUSE
θ value	0.000121331 (rank : 95)	NC score	0.228002 (rank : 345)
Query Neighborhood Hits	1024	Target Neighborhood Hits	496	Shared Neighborhood Hits	172
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ASB2_MOUSE
θ value	0.000121331 (rank : 96)	NC score	0.514311 (rank : 74)
Query Neighborhood Hits	1024	Target Neighborhood Hits	321	Shared Neighborhood Hits	258
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ACBD6_HUMAN
θ value	0.000158464 (rank : 97)	NC score	0.521671 (rank : 63)
Query Neighborhood Hits	1024	Target Neighborhood Hits	304	Shared Neighborhood Hits	250
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

M3K11_HUMAN
θ value	0.000158464 (rank : 98)	NC score	0.120918 (rank : 588)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1136	Shared Neighborhood Hits	251
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

ASB15_HUMAN
θ value	0.00020696 (rank : 99)	NC score	0.502118 (rank : 100)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	255
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

DNMBP_HUMAN
θ value	0.00020696 (rank : 100)	NC score	0.267395 (rank : 284)
Query Neighborhood Hits	1024	Target Neighborhood Hits	413	Shared Neighborhood Hits	192
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PA2G6_MOUSE
θ value	0.00020696 (rank : 101)	NC score	0.509593 (rank : 85)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	253
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

RP3A_HUMAN
θ value	0.00020696 (rank : 102)	NC score	0.048155 (rank : 1298)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

ANKR7_HUMAN
θ value	0.000270298 (rank : 103)	NC score	0.500830 (rank : 104)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	252
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ARI1A_HUMAN
θ value	0.000270298 (rank : 104)	NC score	0.198256 (rank : 383)
Query Neighborhood Hits	1024	Target Neighborhood Hits	787	Shared Neighborhood Hits	296
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BCOR_HUMAN
θ value	0.000270298 (rank : 105)	NC score	0.498536 (rank : 110)
Query Neighborhood Hits	1024	Target Neighborhood Hits	609	Shared Neighborhood Hits	340
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CENG1_MOUSE
θ value	0.000270298 (rank : 106)	NC score	0.239943 (rank : 332)
Query Neighborhood Hits	1024	Target Neighborhood Hits	531	Shared Neighborhood Hits	272
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CO3A1_MOUSE
θ value	0.000270298 (rank : 107)	NC score	0.196449 (rank : 388)
Query Neighborhood Hits	1024	Target Neighborhood Hits	466	Shared Neighborhood Hits	158
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

FYN_HUMAN
θ value	0.000270298 (rank : 108)	NC score	0.132698 (rank : 552)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1078	Shared Neighborhood Hits	202
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	0.000270298 (rank : 109)	NC score	0.134705 (rank : 541)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1073	Shared Neighborhood Hits	202
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

MYO1F_HUMAN
θ value	0.000270298 (rank : 110)	NC score	0.133172 (rank : 548)
Query Neighborhood Hits	1024	Target Neighborhood Hits	275	Shared Neighborhood Hits	169
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

RP1L1_HUMAN
θ value	0.000270298 (rank : 111)	NC score	0.122248 (rank : 585)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1072	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SRC_MOUSE
θ value	0.000270298 (rank : 112)	NC score	0.122722 (rank : 584)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1033	Shared Neighborhood Hits	198
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

WASIP_MOUSE
θ value	0.000270298 (rank : 113)	NC score	0.192694 (rank : 394)
Query Neighborhood Hits	1024	Target Neighborhood Hits	392	Shared Neighborhood Hits	166
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

YES_HUMAN
θ value	0.000270298 (rank : 114)	NC score	0.132522 (rank : 553)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1059	Shared Neighborhood Hits	204
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ACBD6_MOUSE
θ value	0.00035302 (rank : 115)	NC score	0.532569 (rank : 43)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	251
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR25_HUMAN
θ value	0.00035302 (rank : 116)	NC score	0.435445 (rank : 171)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

DAPK1_MOUSE
θ value	0.00035302 (rank : 117)	NC score	0.262324 (rank : 290)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1138	Shared Neighborhood Hits	320
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

GRAP2_MOUSE
θ value	0.00035302 (rank : 118)	NC score	0.318572 (rank : 239)
Query Neighborhood Hits	1024	Target Neighborhood Hits	297	Shared Neighborhood Hits	171
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

MYO1F_MOUSE
θ value	0.00035302 (rank : 119)	NC score	0.130998 (rank : 557)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	160
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NOTC3_HUMAN
θ value	0.00035302 (rank : 120)	NC score	0.258744 (rank : 299)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1062	Shared Neighborhood Hits	357
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	0.00035302 (rank : 121)	NC score	0.253558 (rank : 307)
Query Neighborhood Hits	1024	Target Neighborhood Hits	975	Shared Neighborhood Hits	304
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PCD15_HUMAN
θ value	0.00035302 (rank : 122)	NC score	0.015861 (rank : 1464)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	58
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

USH1G_HUMAN
θ value	0.00035302 (rank : 123)	NC score	0.508709 (rank : 88)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	245
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	0.00035302 (rank : 124)	NC score	0.508764 (rank : 86)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	246
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

CRSP2_HUMAN
θ value	0.000461057 (rank : 125)	NC score	0.151689 (rank : 494)
Query Neighborhood Hits	1024	Target Neighborhood Hits	380	Shared Neighborhood Hits	161
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

HCK_HUMAN
θ value	0.000461057 (rank : 126)	NC score	0.124006 (rank : 581)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1035	Shared Neighborhood Hits	195
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

SFPQ_HUMAN
θ value	0.000461057 (rank : 127)	NC score	0.111690 (rank : 636)
Query Neighborhood Hits	1024	Target Neighborhood Hits	986	Shared Neighborhood Hits	217
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TNI3K_HUMAN
θ value	0.000461057 (rank : 128)	NC score	0.304019 (rank : 256)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1084	Shared Neighborhood Hits	317
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANR32_HUMAN
θ value	0.000602161 (rank : 129)	NC score	0.498731 (rank : 109)
Query Neighborhood Hits	1024	Target Neighborhood Hits	270	Shared Neighborhood Hits	237
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

CSKI2_MOUSE
θ value	0.000602161 (rank : 130)	NC score	0.535119 (rank : 37)
Query Neighborhood Hits	1024	Target Neighborhood Hits	812	Shared Neighborhood Hits	452
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DAPK1_HUMAN
θ value	0.000602161 (rank : 131)	NC score	0.256697 (rank : 302)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1130	Shared Neighborhood Hits	321
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

PCLO_HUMAN
θ value	0.000602161 (rank : 132)	NC score	0.168018 (rank : 457)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2046	Shared Neighborhood Hits	405
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SYNJ1_HUMAN
θ value	0.000602161 (rank : 133)	NC score	0.098832 (rank : 701)
Query Neighborhood Hits	1024	Target Neighborhood Hits	498	Shared Neighborhood Hits	170
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

WASF2_HUMAN
θ value	0.000602161 (rank : 134)	NC score	0.108761 (rank : 649)
Query Neighborhood Hits	1024	Target Neighborhood Hits	280	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

ZDH17_HUMAN
θ value	0.000602161 (rank : 135)	NC score	0.460803 (rank : 150)
Query Neighborhood Hits	1024	Target Neighborhood Hits	334	Shared Neighborhood Hits	254
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ZDH17_MOUSE
θ value	0.000602161 (rank : 136)	NC score	0.459112 (rank : 152)
Query Neighborhood Hits	1024	Target Neighborhood Hits	328	Shared Neighborhood Hits	254
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANFY1_HUMAN
θ value	0.000786445 (rank : 137)	NC score	0.466771 (rank : 143)
Query Neighborhood Hits	1024	Target Neighborhood Hits	480	Shared Neighborhood Hits	261
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKR6_HUMAN
θ value	0.000786445 (rank : 138)	NC score	0.527306 (rank : 51)
Query Neighborhood Hits	1024	Target Neighborhood Hits	439	Shared Neighborhood Hits	278
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR25_MOUSE
θ value	0.000786445 (rank : 139)	NC score	0.432232 (rank : 173)
Query Neighborhood Hits	1024	Target Neighborhood Hits	398	Shared Neighborhood Hits	281
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

CDN2D_HUMAN
θ value	0.000786445 (rank : 140)	NC score	0.515036 (rank : 72)
Query Neighborhood Hits	1024	Target Neighborhood Hits	268	Shared Neighborhood Hits	242
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CO3A1_HUMAN
θ value	0.000786445 (rank : 141)	NC score	0.190368 (rank : 400)
Query Neighborhood Hits	1024	Target Neighborhood Hits	452	Shared Neighborhood Hits	154
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CSKI2_HUMAN
θ value	0.000786445 (rank : 142)	NC score	0.527061 (rank : 53)
Query Neighborhood Hits	1024	Target Neighborhood Hits	747	Shared Neighborhood Hits	401
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GRAP2_HUMAN
θ value	0.000786445 (rank : 143)	NC score	0.318163 (rank : 240)
Query Neighborhood Hits	1024	Target Neighborhood Hits	304	Shared Neighborhood Hits	173
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

HCK_MOUSE
θ value	0.000786445 (rank : 144)	NC score	0.123591 (rank : 582)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1029	Shared Neighborhood Hits	196
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

NFKB2_HUMAN
θ value	0.000786445 (rank : 145)	NC score	0.437681 (rank : 170)
Query Neighborhood Hits	1024	Target Neighborhood Hits	325	Shared Neighborhood Hits	255
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

SELV_HUMAN
θ value	0.000786445 (rank : 146)	NC score	0.111134 (rank : 641)
Query Neighborhood Hits	1024	Target Neighborhood Hits	118	Shared Neighborhood Hits	54
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SH3K1_HUMAN
θ value	0.000786445 (rank : 147)	NC score	0.320518 (rank : 237)
Query Neighborhood Hits	1024	Target Neighborhood Hits	341	Shared Neighborhood Hits	181
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	0.000786445 (rank : 148)	NC score	0.319889 (rank : 238)
Query Neighborhood Hits	1024	Target Neighborhood Hits	332	Shared Neighborhood Hits	179
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SRC_HUMAN
θ value	0.000786445 (rank : 149)	NC score	0.128645 (rank : 567)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1058	Shared Neighborhood Hits	205
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

YES_MOUSE
θ value	0.000786445 (rank : 150)	NC score	0.132191 (rank : 555)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1052	Shared Neighborhood Hits	201
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ANFY1_MOUSE
θ value	0.00102713 (rank : 151)	NC score	0.466483 (rank : 144)
Query Neighborhood Hits	1024	Target Neighborhood Hits	480	Shared Neighborhood Hits	261
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB13_HUMAN
θ value	0.00102713 (rank : 152)	NC score	0.512848 (rank : 79)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

CPSF6_HUMAN
θ value	0.00102713 (rank : 153)	NC score	0.166695 (rank : 463)
Query Neighborhood Hits	1024	Target Neighborhood Hits	359	Shared Neighborhood Hits	142
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	0.00102713 (rank : 154)	NC score	0.167083 (rank : 462)
Query Neighborhood Hits	1024	Target Neighborhood Hits	356	Shared Neighborhood Hits	143
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

GA2L1_HUMAN
θ value	0.00102713 (rank : 155)	NC score	0.097885 (rank : 704)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

IKBE_MOUSE
θ value	0.00102713 (rank : 156)	NC score	0.504156 (rank : 96)
Query Neighborhood Hits	1024	Target Neighborhood Hits	308	Shared Neighborhood Hits	252
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

INVS_HUMAN
θ value	0.00102713 (rank : 157)	NC score	0.519791 (rank : 66)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	302
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	0.00102713 (rank : 158)	NC score	0.524066 (rank : 56)
Query Neighborhood Hits	1024	Target Neighborhood Hits	609	Shared Neighborhood Hits	359
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

LYN_HUMAN
θ value	0.00102713 (rank : 159)	NC score	0.112941 (rank : 625)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1022	Shared Neighborhood Hits	179
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

SCAR3_HUMAN
θ value	0.00102713 (rank : 160)	NC score	0.156805 (rank : 486)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	77
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

SCAR3_MOUSE
θ value	0.00102713 (rank : 161)	NC score	0.157203 (rank : 484)
Query Neighborhood Hits	1024	Target Neighborhood Hits	239	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

SET1A_HUMAN
θ value	0.00102713 (rank : 162)	NC score	0.128146 (rank : 571)
Query Neighborhood Hits	1024	Target Neighborhood Hits	690	Shared Neighborhood Hits	167
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SRRM1_HUMAN
θ value	0.00102713 (rank : 163)	NC score	0.163771 (rank : 468)
Query Neighborhood Hits	1024	Target Neighborhood Hits	690	Shared Neighborhood Hits	181
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ZDH13_HUMAN
θ value	0.00102713 (rank : 164)	NC score	0.458769 (rank : 153)
Query Neighborhood Hits	1024	Target Neighborhood Hits	322	Shared Neighborhood Hits	252
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ZDH13_MOUSE
θ value	0.00102713 (rank : 165)	NC score	0.457656 (rank : 156)
Query Neighborhood Hits	1024	Target Neighborhood Hits	329	Shared Neighborhood Hits	254
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ASB13_MOUSE
θ value	0.00134147 (rank : 166)	NC score	0.512396 (rank : 80)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	253
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB15_MOUSE
θ value	0.00134147 (rank : 167)	NC score	0.493411 (rank : 115)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	250
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

BCL3_HUMAN
θ value	0.00134147 (rank : 168)	NC score	0.511872 (rank : 82)
Query Neighborhood Hits	1024	Target Neighborhood Hits	324	Shared Neighborhood Hits	267
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

BLK_HUMAN
θ value	0.00134147 (rank : 169)	NC score	0.116160 (rank : 613)
Query Neighborhood Hits	1024	Target Neighborhood Hits	994	Shared Neighborhood Hits	169
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	0.00134147 (rank : 170)	NC score	0.113995 (rank : 621)
Query Neighborhood Hits	1024	Target Neighborhood Hits	992	Shared Neighborhood Hits	162
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

DGKI_HUMAN
θ value	0.00134147 (rank : 171)	NC score	0.261819 (rank : 291)
Query Neighborhood Hits	1024	Target Neighborhood Hits	609	Shared Neighborhood Hits	207
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

GPS2_HUMAN
θ value	0.00134147 (rank : 172)	NC score	0.128417 (rank : 568)
Query Neighborhood Hits	1024	Target Neighborhood Hits	459	Shared Neighborhood Hits	126
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

M3KL4_HUMAN
θ value	0.00134147 (rank : 173)	NC score	0.117531 (rank : 606)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1087	Shared Neighborhood Hits	211
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

PA2G6_HUMAN
θ value	0.00134147 (rank : 174)	NC score	0.500559 (rank : 107)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

SFPQ_MOUSE
θ value	0.00134147 (rank : 175)	NC score	0.116135 (rank : 614)
Query Neighborhood Hits	1024	Target Neighborhood Hits	958	Shared Neighborhood Hits	214
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

VAV_HUMAN
θ value	0.00134147 (rank : 176)	NC score	0.225461 (rank : 349)
Query Neighborhood Hits	1024	Target Neighborhood Hits	452	Shared Neighborhood Hits	174
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ARHG9_HUMAN
θ value	0.00175202 (rank : 177)	NC score	0.212943 (rank : 363)
Query Neighborhood Hits	1024	Target Neighborhood Hits	235	Shared Neighborhood Hits	144
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	0.00175202 (rank : 178)	NC score	0.212752 (rank : 364)
Query Neighborhood Hits	1024	Target Neighborhood Hits	234	Shared Neighborhood Hits	142
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

CD2AP_MOUSE
θ value	0.00175202 (rank : 179)	NC score	0.315439 (rank : 243)
Query Neighborhood Hits	1024	Target Neighborhood Hits	336	Shared Neighborhood Hits	188
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CO1A2_MOUSE
θ value	0.00175202 (rank : 180)	NC score	0.195077 (rank : 392)
Query Neighborhood Hits	1024	Target Neighborhood Hits	388	Shared Neighborhood Hits	145
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO5A1_MOUSE
θ value	0.00175202 (rank : 181)	NC score	0.185439 (rank : 414)
Query Neighborhood Hits	1024	Target Neighborhood Hits	419	Shared Neighborhood Hits	155
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

DDFL1_HUMAN
θ value	0.00175202 (rank : 182)	NC score	0.276356 (rank : 277)
Query Neighborhood Hits	1024	Target Neighborhood Hits	353	Shared Neighborhood Hits	235
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DNMBP_MOUSE
θ value	0.00175202 (rank : 183)	NC score	0.253876 (rank : 305)
Query Neighborhood Hits	1024	Target Neighborhood Hits	435	Shared Neighborhood Hits	196
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

MLL4_HUMAN
θ value	0.00175202 (rank : 184)	NC score	0.120574 (rank : 589)
Query Neighborhood Hits	1024	Target Neighborhood Hits	722	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PKHA4_MOUSE
θ value	0.00175202 (rank : 185)	NC score	0.074514 (rank : 848)
Query Neighborhood Hits	1024	Target Neighborhood Hits	202	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RIPK4_HUMAN
θ value	0.00175202 (rank : 186)	NC score	0.365830 (rank : 207)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1094	Shared Neighborhood Hits	323
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

RN5A_HUMAN
θ value	0.00175202 (rank : 187)	NC score	0.492467 (rank : 117)
Query Neighborhood Hits	1024	Target Neighborhood Hits	608	Shared Neighborhood Hits	282
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

STAT2_MOUSE
θ value	0.00175202 (rank : 188)	NC score	0.055834 (rank : 1118)
Query Neighborhood Hits	1024	Target Neighborhood Hits	175	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

VAV_MOUSE
θ value	0.00175202 (rank : 189)	NC score	0.224382 (rank : 352)
Query Neighborhood Hits	1024	Target Neighborhood Hits	430	Shared Neighborhood Hits	173
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

ABI2_HUMAN
θ value	0.00228821 (rank : 190)	NC score	0.289644 (rank : 267)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	207
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ANKS1_MOUSE
θ value	0.00228821 (rank : 191)	NC score	0.487522 (rank : 126)
Query Neighborhood Hits	1024	Target Neighborhood Hits	453	Shared Neighborhood Hits	274
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

CENB2_HUMAN
θ value	0.00228821 (rank : 192)	NC score	0.374196 (rank : 198)
Query Neighborhood Hits	1024	Target Neighborhood Hits	425	Shared Neighborhood Hits	249
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ENAH_MOUSE
θ value	0.00228821 (rank : 193)	NC score	0.128185 (rank : 569)
Query Neighborhood Hits	1024	Target Neighborhood Hits	919	Shared Neighborhood Hits	196
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

IKBE_HUMAN
θ value	0.00228821 (rank : 194)	NC score	0.492663 (rank : 116)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	249
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

NOTC4_HUMAN
θ value	0.00228821 (rank : 195)	NC score	0.271555 (rank : 282)
Query Neighborhood Hits	1024	Target Neighborhood Hits	905	Shared Neighborhood Hits	280
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

OGFR_HUMAN
θ value	0.00228821 (rank : 196)	NC score	0.321171 (rank : 236)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1582	Shared Neighborhood Hits	504
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

POTE8_HUMAN
θ value	0.00228821 (rank : 197)	NC score	0.458134 (rank : 154)
Query Neighborhood Hits	1024	Target Neighborhood Hits	337	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

SH3G1_MOUSE
θ value	0.00228821 (rank : 198)	NC score	0.264999 (rank : 287)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	162
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SRGP2_HUMAN
θ value	0.00228821 (rank : 199)	NC score	0.170039 (rank : 453)
Query Neighborhood Hits	1024	Target Neighborhood Hits	331	Shared Neighborhood Hits	147
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SYP2L_MOUSE
θ value	0.00228821 (rank : 200)	NC score	0.077273 (rank : 827)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ANR15_HUMAN
θ value	0.00298849 (rank : 201)	NC score	0.460175 (rank : 151)
Query Neighborhood Hits	1024	Target Neighborhood Hits	478	Shared Neighborhood Hits	266
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR32_MOUSE
θ value	0.00298849 (rank : 202)	NC score	0.489898 (rank : 124)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	237
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR45_HUMAN
θ value	0.00298849 (rank : 203)	NC score	0.449428 (rank : 165)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	178
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANS4B_MOUSE
θ value	0.00298849 (rank : 204)	NC score	0.499917 (rank : 108)
Query Neighborhood Hits	1024	Target Neighborhood Hits	294	Shared Neighborhood Hits	241
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

BCOR_MOUSE
θ value	0.00298849 (rank : 205)	NC score	0.480669 (rank : 130)
Query Neighborhood Hits	1024	Target Neighborhood Hits	521	Shared Neighborhood Hits	304
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CDN2D_MOUSE
θ value	0.00298849 (rank : 206)	NC score	0.508646 (rank : 89)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	242
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CENB5_HUMAN
θ value	0.00298849 (rank : 207)	NC score	0.376759 (rank : 196)
Query Neighborhood Hits	1024	Target Neighborhood Hits	395	Shared Neighborhood Hits	254
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CO1A2_HUMAN
θ value	0.00298849 (rank : 208)	NC score	0.184924 (rank : 415)
Query Neighborhood Hits	1024	Target Neighborhood Hits	329	Shared Neighborhood Hits	127
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO5A1_HUMAN
θ value	0.00298849 (rank : 209)	NC score	0.184622 (rank : 418)
Query Neighborhood Hits	1024	Target Neighborhood Hits	434	Shared Neighborhood Hits	158
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CTTB2_HUMAN
θ value	0.00298849 (rank : 210)	NC score	0.463190 (rank : 148)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1061	Shared Neighborhood Hits	331
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

DDFL1_MOUSE
θ value	0.00298849 (rank : 211)	NC score	0.337332 (rank : 228)
Query Neighborhood Hits	1024	Target Neighborhood Hits	324	Shared Neighborhood Hits	242
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

HXD8_MOUSE
θ value	0.00298849 (rank : 212)	NC score	0.012545 (rank : 1488)
Query Neighborhood Hits	1024	Target Neighborhood Hits	333	Shared Neighborhood Hits	15
SwissProt Accessions	P23463	Gene names	Hoxd8, Hox-4.3, Hoxd-8
Domain Architecture
Description	Homeobox protein Hox-D8 (Hox-4.3) (Hox-5.4).

LYN_MOUSE
θ value	0.00298849 (rank : 213)	NC score	0.111347 (rank : 639)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1023	Shared Neighborhood Hits	182
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

NCK2_HUMAN
θ value	0.00298849 (rank : 214)	NC score	0.292905 (rank : 265)
Query Neighborhood Hits	1024	Target Neighborhood Hits	310	Shared Neighborhood Hits	171
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

PPIP1_MOUSE
θ value	0.00298849 (rank : 215)	NC score	0.283731 (rank : 272)
Query Neighborhood Hits	1024	Target Neighborhood Hits	377	Shared Neighborhood Hits	169
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

RERE_HUMAN
θ value	0.00298849 (rank : 216)	NC score	0.134481 (rank : 542)
Query Neighborhood Hits	1024	Target Neighborhood Hits	779	Shared Neighborhood Hits	225
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SPT5H_HUMAN
θ value	0.00298849 (rank : 217)	NC score	0.167505 (rank : 460)
Query Neighborhood Hits	1024	Target Neighborhood Hits	436	Shared Neighborhood Hits	194
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	0.00298849 (rank : 218)	NC score	0.167405 (rank : 461)
Query Neighborhood Hits	1024	Target Neighborhood Hits	437	Shared Neighborhood Hits	192
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRGP2_MOUSE
θ value	0.00298849 (rank : 219)	NC score	0.172155 (rank : 449)
Query Neighborhood Hits	1024	Target Neighborhood Hits	324	Shared Neighborhood Hits	145
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

TRPA1_MOUSE
θ value	0.00298849 (rank : 220)	NC score	0.505998 (rank : 93)
Query Neighborhood Hits	1024	Target Neighborhood Hits	343	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

UACA_HUMAN
θ value	0.00298849 (rank : 221)	NC score	0.304200 (rank : 255)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1622	Shared Neighborhood Hits	326
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ANKR2_MOUSE
θ value	0.00390308 (rank : 222)	NC score	0.522351 (rank : 61)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	256
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR23_HUMAN
θ value	0.00390308 (rank : 223)	NC score	0.523500 (rank : 58)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	255
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ARHG7_HUMAN
θ value	0.00390308 (rank : 224)	NC score	0.259294 (rank : 296)
Query Neighborhood Hits	1024	Target Neighborhood Hits	347	Shared Neighborhood Hits	170
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

EHMT1_HUMAN
θ value	0.00390308 (rank : 225)	NC score	0.500823 (rank : 105)
Query Neighborhood Hits	1024	Target Neighborhood Hits	417	Shared Neighborhood Hits	274
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

FOXC1_MOUSE
θ value	0.00390308 (rank : 226)	NC score	0.033209 (rank : 1367)
Query Neighborhood Hits	1024	Target Neighborhood Hits	218	Shared Neighborhood Hits	61
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

ILK1_HUMAN
θ value	0.00390308 (rank : 227)	NC score	0.362845 (rank : 209)
Query Neighborhood Hits	1024	Target Neighborhood Hits	857	Shared Neighborhood Hits	296
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	0.00390308 (rank : 228)	NC score	0.373715 (rank : 199)
Query Neighborhood Hits	1024	Target Neighborhood Hits	848	Shared Neighborhood Hits	296
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

NOTC1_HUMAN
θ value	0.00390308 (rank : 229)	NC score	0.242238 (rank : 327)
Query Neighborhood Hits	1024	Target Neighborhood Hits	906	Shared Neighborhood Hits	275
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SRRM2_HUMAN
θ value	0.00390308 (rank : 230)	NC score	0.142639 (rank : 513)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1296	Shared Neighborhood Hits	259
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRIO_HUMAN
θ value	0.00390308 (rank : 231)	NC score	0.054174 (rank : 1170)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1580	Shared Neighborhood Hits	173
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

XRCC1_MOUSE
θ value	0.00390308 (rank : 232)	NC score	0.070261 (rank : 890)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	38
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

CASC3_HUMAN
θ value	0.00509761 (rank : 233)	NC score	0.078681 (rank : 817)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	45
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

CN032_MOUSE
θ value	0.00509761 (rank : 234)	NC score	0.144697 (rank : 507)
Query Neighborhood Hits	1024	Target Neighborhood Hits	233	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CO5A3_HUMAN
θ value	0.00509761 (rank : 235)	NC score	0.186317 (rank : 411)
Query Neighborhood Hits	1024	Target Neighborhood Hits	433	Shared Neighborhood Hits	156
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

COIA1_HUMAN
θ value	0.00509761 (rank : 236)	NC score	0.167819 (rank : 458)
Query Neighborhood Hits	1024	Target Neighborhood Hits	447	Shared Neighborhood Hits	177
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

EP400_HUMAN
θ value	0.00509761 (rank : 237)	NC score	0.054912 (rank : 1151)
Query Neighborhood Hits	1024	Target Neighborhood Hits	556	Shared Neighborhood Hits	141
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

GABP3_MOUSE
θ value	0.00509761 (rank : 238)	NC score	0.521870 (rank : 62)
Query Neighborhood Hits	1024	Target Neighborhood Hits	330	Shared Neighborhood Hits	252
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

GLSL_HUMAN
θ value	0.00509761 (rank : 239)	NC score	0.369809 (rank : 204)
Query Neighborhood Hits	1024	Target Neighborhood Hits	211	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

MDC1_HUMAN
θ value	0.00509761 (rank : 240)	NC score	0.195173 (rank : 391)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1446	Shared Neighborhood Hits	322
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYO1E_HUMAN
θ value	0.00509761 (rank : 241)	NC score	0.127788 (rank : 573)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	165
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

NCK1_HUMAN
θ value	0.00509761 (rank : 242)	NC score	0.299873 (rank : 258)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	168
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NOTC4_MOUSE
θ value	0.00509761 (rank : 243)	NC score	0.274957 (rank : 279)
Query Neighborhood Hits	1024	Target Neighborhood Hits	872	Shared Neighborhood Hits	265
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PELP1_MOUSE
θ value	0.00509761 (rank : 244)	NC score	0.169684 (rank : 454)
Query Neighborhood Hits	1024	Target Neighborhood Hits	709	Shared Neighborhood Hits	249
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PPIP1_HUMAN
θ value	0.00509761 (rank : 245)	NC score	0.275537 (rank : 278)
Query Neighborhood Hits	1024	Target Neighborhood Hits	389	Shared Neighborhood Hits	170
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

RKHD1_HUMAN
θ value	0.00509761 (rank : 246)	NC score	0.059370 (rank : 1033)
Query Neighborhood Hits	1024	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

SH3G2_MOUSE
θ value	0.00509761 (rank : 247)	NC score	0.266446 (rank : 285)
Query Neighborhood Hits	1024	Target Neighborhood Hits	319	Shared Neighborhood Hits	161
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SYNJ1_MOUSE
θ value	0.00509761 (rank : 248)	NC score	0.108253 (rank : 652)
Query Neighborhood Hits	1024	Target Neighborhood Hits	516	Shared Neighborhood Hits	185
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYP2L_HUMAN
θ value	0.00509761 (rank : 249)	NC score	0.092920 (rank : 734)
Query Neighborhood Hits	1024	Target Neighborhood Hits	400	Shared Neighborhood Hits	125
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TEC_HUMAN
θ value	0.00509761 (rank : 250)	NC score	0.100269 (rank : 698)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1006	Shared Neighborhood Hits	170
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

WASP_MOUSE
θ value	0.00509761 (rank : 251)	NC score	0.112302 (rank : 631)
Query Neighborhood Hits	1024	Target Neighborhood Hits	223	Shared Neighborhood Hits	99
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ANKS1_HUMAN
θ value	0.00665767 (rank : 252)	NC score	0.490097 (rank : 121)
Query Neighborhood Hits	1024	Target Neighborhood Hits	438	Shared Neighborhood Hits	265
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANR19_HUMAN
θ value	0.00665767 (rank : 253)	NC score	0.453064 (rank : 160)
Query Neighborhood Hits	1024	Target Neighborhood Hits	276	Shared Neighborhood Hits	246
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR45_MOUSE
θ value	0.00665767 (rank : 254)	NC score	0.469693 (rank : 139)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	183
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASB10_MOUSE
θ value	0.00665767 (rank : 255)	NC score	0.513000 (rank : 78)
Query Neighborhood Hits	1024	Target Neighborhood Hits	301	Shared Neighborhood Hits	254
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASZ1_MOUSE
θ value	0.00665767 (rank : 256)	NC score	0.508738 (rank : 87)
Query Neighborhood Hits	1024	Target Neighborhood Hits	319	Shared Neighborhood Hits	248
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

BTK_MOUSE
θ value	0.00665767 (rank : 257)	NC score	0.112075 (rank : 633)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1017	Shared Neighborhood Hits	193
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CD2AP_HUMAN
θ value	0.00665767 (rank : 258)	NC score	0.309407 (rank : 250)
Query Neighborhood Hits	1024	Target Neighborhood Hits	315	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CO4A5_HUMAN
θ value	0.00665767 (rank : 259)	NC score	0.170240 (rank : 452)
Query Neighborhood Hits	1024	Target Neighborhood Hits	383	Shared Neighborhood Hits	144
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO8A1_HUMAN
θ value	0.00665767 (rank : 260)	NC score	0.156805 (rank : 485)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	119
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

DGKZ_HUMAN
θ value	0.00665767 (rank : 261)	NC score	0.289187 (rank : 270)
Query Neighborhood Hits	1024	Target Neighborhood Hits	551	Shared Neighborhood Hits	211
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

GLSL_MOUSE
θ value	0.00665767 (rank : 262)	NC score	0.361492 (rank : 210)
Query Neighborhood Hits	1024	Target Neighborhood Hits	212	Shared Neighborhood Hits	187
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

MIB1_HUMAN
θ value	0.00665767 (rank : 263)	NC score	0.489908 (rank : 123)
Query Neighborhood Hits	1024	Target Neighborhood Hits	470	Shared Neighborhood Hits	260
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.00665767 (rank : 264)	NC score	0.490046 (rank : 122)
Query Neighborhood Hits	1024	Target Neighborhood Hits	471	Shared Neighborhood Hits	260
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MLL2_HUMAN
θ value	0.00665767 (rank : 265)	NC score	0.158718 (rank : 480)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1788	Shared Neighborhood Hits	380
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PYGO2_HUMAN
θ value	0.00665767 (rank : 266)	NC score	0.105465 (rank : 666)
Query Neighborhood Hits	1024	Target Neighborhood Hits	189	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RFXK_HUMAN
θ value	0.00665767 (rank : 267)	NC score	0.501708 (rank : 102)
Query Neighborhood Hits	1024	Target Neighborhood Hits	282	Shared Neighborhood Hits	246
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

TRPA1_HUMAN
θ value	0.00665767 (rank : 268)	NC score	0.500648 (rank : 106)
Query Neighborhood Hits	1024	Target Neighborhood Hits	339	Shared Neighborhood Hits	258
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

WASIP_HUMAN
θ value	0.00665767 (rank : 269)	NC score	0.184145 (rank : 421)
Query Neighborhood Hits	1024	Target Neighborhood Hits	458	Shared Neighborhood Hits	157
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ANKR2_HUMAN
θ value	0.00869519 (rank : 270)	NC score	0.520304 (rank : 64)
Query Neighborhood Hits	1024	Target Neighborhood Hits	321	Shared Neighborhood Hits	256
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR46_HUMAN
θ value	0.00869519 (rank : 271)	NC score	0.536219 (rank : 34)
Query Neighborhood Hits	1024	Target Neighborhood Hits	281	Shared Neighborhood Hits	248
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANS4B_HUMAN
θ value	0.00869519 (rank : 272)	NC score	0.502299 (rank : 98)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	245
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ARHG6_HUMAN
θ value	0.00869519 (rank : 273)	NC score	0.238464 (rank : 335)
Query Neighborhood Hits	1024	Target Neighborhood Hits	376	Shared Neighborhood Hits	166
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ASB3_HUMAN
θ value	0.00869519 (rank : 274)	NC score	0.513654 (rank : 76)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

COBA2_HUMAN
θ value	0.00869519 (rank : 275)	NC score	0.182007 (rank : 431)
Query Neighborhood Hits	1024	Target Neighborhood Hits	408	Shared Neighborhood Hits	143
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

FRK_HUMAN
θ value	0.00869519 (rank : 276)	NC score	0.112541 (rank : 628)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1058	Shared Neighborhood Hits	198
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

GABP2_HUMAN
θ value	0.00869519 (rank : 277)	NC score	0.513374 (rank : 77)
Query Neighborhood Hits	1024	Target Neighborhood Hits	454	Shared Neighborhood Hits	266
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ILK_MOUSE
θ value	0.00869519 (rank : 278)	NC score	0.360303 (rank : 213)
Query Neighborhood Hits	1024	Target Neighborhood Hits	858	Shared Neighborhood Hits	300
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

MTSS1_MOUSE
θ value	0.00869519 (rank : 279)	NC score	0.176902 (rank : 436)
Query Neighborhood Hits	1024	Target Neighborhood Hits	592	Shared Neighborhood Hits	242
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PTN23_HUMAN
θ value	0.00869519 (rank : 280)	NC score	0.055630 (rank : 1124)
Query Neighborhood Hits	1024	Target Neighborhood Hits	646	Shared Neighborhood Hits	159
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SH3G2_HUMAN
θ value	0.00869519 (rank : 281)	NC score	0.266369 (rank : 286)
Query Neighborhood Hits	1024	Target Neighborhood Hits	324	Shared Neighborhood Hits	164
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SPEG_HUMAN
θ value	0.00869519 (rank : 282)	NC score	0.058290 (rank : 1058)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1762	Shared Neighborhood Hits	300
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

STAM2_MOUSE
θ value	0.00869519 (rank : 283)	NC score	0.264128 (rank : 289)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	169
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

UACA_MOUSE
θ value	0.00869519 (rank : 284)	NC score	0.289488 (rank : 268)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1620	Shared Neighborhood Hits	322
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ABI2_MOUSE
θ value	0.0113563 (rank : 285)	NC score	0.273052 (rank : 281)
Query Neighborhood Hits	1024	Target Neighborhood Hits	266	Shared Neighborhood Hits	179
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ASB16_HUMAN
θ value	0.0113563 (rank : 286)	NC score	0.495507 (rank : 113)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	251
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB3_MOUSE
θ value	0.0113563 (rank : 287)	NC score	0.515521 (rank : 71)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB5_HUMAN
θ value	0.0113563 (rank : 288)	NC score	0.493681 (rank : 114)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	246
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CENG3_HUMAN
θ value	0.0113563 (rank : 289)	NC score	0.225092 (rank : 350)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	225
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.0113563 (rank : 290)	NC score	0.225798 (rank : 347)
Query Neighborhood Hits	1024	Target Neighborhood Hits	467	Shared Neighborhood Hits	229
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

COBA2_MOUSE
θ value	0.0113563 (rank : 291)	NC score	0.183307 (rank : 425)
Query Neighborhood Hits	1024	Target Neighborhood Hits	501	Shared Neighborhood Hits	172
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COGA1_HUMAN
θ value	0.0113563 (rank : 292)	NC score	0.168766 (rank : 456)
Query Neighborhood Hits	1024	Target Neighborhood Hits	345	Shared Neighborhood Hits	131
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

HXA4_MOUSE
θ value	0.0113563 (rank : 293)	NC score	0.013622 (rank : 1483)
Query Neighborhood Hits	1024	Target Neighborhood Hits	379	Shared Neighborhood Hits	37
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).

IRX3_HUMAN
θ value	0.0113563 (rank : 294)	NC score	0.038508 (rank : 1332)
Query Neighborhood Hits	1024	Target Neighborhood Hits	342	Shared Neighborhood Hits	44
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

SHAN1_HUMAN
θ value	0.0113563 (rank : 295)	NC score	0.514294 (rank : 75)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1041	Shared Neighborhood Hits	500
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SPTA2_HUMAN
θ value	0.0113563 (rank : 296)	NC score	0.129699 (rank : 563)
Query Neighborhood Hits	1024	Target Neighborhood Hits	888	Shared Neighborhood Hits	183
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRGP1_HUMAN
θ value	0.0113563 (rank : 297)	NC score	0.159369 (rank : 476)
Query Neighborhood Hits	1024	Target Neighborhood Hits	390	Shared Neighborhood Hits	149
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

ANR42_MOUSE
θ value	0.0148317 (rank : 298)	NC score	0.518206 (rank : 68)
Query Neighborhood Hits	1024	Target Neighborhood Hits	334	Shared Neighborhood Hits	253
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR47_HUMAN
θ value	0.0148317 (rank : 299)	NC score	0.441565 (rank : 169)
Query Neighborhood Hits	1024	Target Neighborhood Hits	369	Shared Neighborhood Hits	264
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB8_HUMAN
θ value	0.0148317 (rank : 300)	NC score	0.505631 (rank : 94)
Query Neighborhood Hits	1024	Target Neighborhood Hits	294	Shared Neighborhood Hits	252
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	0.0148317 (rank : 301)	NC score	0.505538 (rank : 95)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

BCL9_MOUSE
θ value	0.0148317 (rank : 302)	NC score	0.222052 (rank : 354)
Query Neighborhood Hits	1024	Target Neighborhood Hits	770	Shared Neighborhood Hits	310
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BTK_HUMAN
θ value	0.0148317 (rank : 303)	NC score	0.117909 (rank : 605)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1026	Shared Neighborhood Hits	200
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

CO4A2_HUMAN
θ value	0.0148317 (rank : 304)	NC score	0.187029 (rank : 409)
Query Neighborhood Hits	1024	Target Neighborhood Hits	454	Shared Neighborhood Hits	185
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COHA1_HUMAN
θ value	0.0148317 (rank : 305)	NC score	0.164004 (rank : 467)
Query Neighborhood Hits	1024	Target Neighborhood Hits	400	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DGKZ_MOUSE
θ value	0.0148317 (rank : 306)	NC score	0.270906 (rank : 283)
Query Neighborhood Hits	1024	Target Neighborhood Hits	542	Shared Neighborhood Hits	200
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

FGR_HUMAN
θ value	0.0148317 (rank : 307)	NC score	0.130360 (rank : 560)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1067	Shared Neighborhood Hits	202
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

GA2L1_MOUSE
θ value	0.0148317 (rank : 308)	NC score	0.067071 (rank : 928)
Query Neighborhood Hits	1024	Target Neighborhood Hits	114	Shared Neighborhood Hits	40
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

HCN2_HUMAN
θ value	0.0148317 (rank : 309)	NC score	0.062824 (rank : 982)
Query Neighborhood Hits	1024	Target Neighborhood Hits	369	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

K1802_HUMAN
θ value	0.0148317 (rank : 310)	NC score	0.101813 (rank : 685)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1378	Shared Neighborhood Hits	288
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LCK_HUMAN
θ value	0.0148317 (rank : 311)	NC score	0.103117 (rank : 675)
Query Neighborhood Hits	1024	Target Neighborhood Hits	987	Shared Neighborhood Hits	147
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	0.0148317 (rank : 312)	NC score	0.102428 (rank : 682)
Query Neighborhood Hits	1024	Target Neighborhood Hits	981	Shared Neighborhood Hits	144
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

MIB2_HUMAN
θ value	0.0148317 (rank : 313)	NC score	0.479737 (rank : 132)
Query Neighborhood Hits	1024	Target Neighborhood Hits	438	Shared Neighborhood Hits	260
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

PER1_MOUSE
θ value	0.0148317 (rank : 314)	NC score	0.051962 (rank : 1232)
Query Neighborhood Hits	1024	Target Neighborhood Hits	235	Shared Neighborhood Hits	84
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PEX13_HUMAN
θ value	0.0148317 (rank : 315)	NC score	0.224568 (rank : 351)
Query Neighborhood Hits	1024	Target Neighborhood Hits	128	Shared Neighborhood Hits	102
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

SC24D_HUMAN
θ value	0.0148317 (rank : 316)	NC score	0.069570 (rank : 900)
Query Neighborhood Hits	1024	Target Neighborhood Hits	173	Shared Neighborhood Hits	73
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

A20A3_HUMAN
θ value	0.0193708 (rank : 317)	NC score	0.396203 (rank : 186)
Query Neighborhood Hits	1024	Target Neighborhood Hits	692	Shared Neighborhood Hits	264
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	0.0193708 (rank : 318)	NC score	0.393466 (rank : 188)
Query Neighborhood Hits	1024	Target Neighborhood Hits	710	Shared Neighborhood Hits	265
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ARHG6_MOUSE
θ value	0.0193708 (rank : 319)	NC score	0.242421 (rank : 326)
Query Neighborhood Hits	1024	Target Neighborhood Hits	394	Shared Neighborhood Hits	170
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ASB11_MOUSE
θ value	0.0193708 (rank : 320)	NC score	0.485144 (rank : 127)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB14_MOUSE
θ value	0.0193708 (rank : 321)	NC score	0.484982 (rank : 128)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	249
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB1_MOUSE
θ value	0.0193708 (rank : 322)	NC score	0.469404 (rank : 140)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	247
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

BCL3_MOUSE
θ value	0.0193708 (rank : 323)	NC score	0.507711 (rank : 91)
Query Neighborhood Hits	1024	Target Neighborhood Hits	388	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

CASC3_MOUSE
θ value	0.0193708 (rank : 324)	NC score	0.100872 (rank : 691)
Query Neighborhood Hits	1024	Target Neighborhood Hits	333	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CO4A2_MOUSE
θ value	0.0193708 (rank : 325)	NC score	0.190243 (rank : 402)
Query Neighborhood Hits	1024	Target Neighborhood Hits	492	Shared Neighborhood Hits	191
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A4_HUMAN
θ value	0.0193708 (rank : 326)	NC score	0.192886 (rank : 393)
Query Neighborhood Hits	1024	Target Neighborhood Hits	440	Shared Neighborhood Hits	173
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO9A2_MOUSE
θ value	0.0193708 (rank : 327)	NC score	0.175315 (rank : 440)
Query Neighborhood Hits	1024	Target Neighborhood Hits	279	Shared Neighborhood Hits	118
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CS007_MOUSE
θ value	0.0193708 (rank : 328)	NC score	0.107522 (rank : 655)
Query Neighborhood Hits	1024	Target Neighborhood Hits	464	Shared Neighborhood Hits	154
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

ELOA3_HUMAN
θ value	0.0193708 (rank : 329)	NC score	0.050810 (rank : 1263)
Query Neighborhood Hits	1024	Target Neighborhood Hits	98	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

HCLS1_HUMAN
θ value	0.0193708 (rank : 330)	NC score	0.296209 (rank : 261)
Query Neighborhood Hits	1024	Target Neighborhood Hits	358	Shared Neighborhood Hits	221
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

M3K9_HUMAN
θ value	0.0193708 (rank : 331)	NC score	0.110145 (rank : 645)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1123	Shared Neighborhood Hits	234
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NFAC4_HUMAN
θ value	0.0193708 (rank : 332)	NC score	0.048769 (rank : 1294)
Query Neighborhood Hits	1024	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

NFKB2_MOUSE
θ value	0.0193708 (rank : 333)	NC score	0.427591 (rank : 175)
Query Neighborhood Hits	1024	Target Neighborhood Hits	326	Shared Neighborhood Hits	257
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

PACN3_MOUSE
θ value	0.0193708 (rank : 334)	NC score	0.234908 (rank : 339)
Query Neighborhood Hits	1024	Target Neighborhood Hits	380	Shared Neighborhood Hits	163
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

STAM1_HUMAN
θ value	0.0193708 (rank : 335)	NC score	0.259366 (rank : 295)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	172
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	0.0193708 (rank : 336)	NC score	0.259655 (rank : 293)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	173
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TCGAP_HUMAN
θ value	0.0193708 (rank : 337)	NC score	0.245350 (rank : 321)
Query Neighborhood Hits	1024	Target Neighborhood Hits	872	Shared Neighborhood Hits	413
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

WASF2_MOUSE
θ value	0.0193708 (rank : 338)	NC score	0.114429 (rank : 619)
Query Neighborhood Hits	1024	Target Neighborhood Hits	315	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

A20A1_HUMAN
θ value	0.0252991 (rank : 339)	NC score	0.394787 (rank : 187)
Query Neighborhood Hits	1024	Target Neighborhood Hits	698	Shared Neighborhood Hits	261
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

ANR23_MOUSE
θ value	0.0252991 (rank : 340)	NC score	0.522617 (rank : 60)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	256
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR46_MOUSE
θ value	0.0252991 (rank : 341)	NC score	0.525365 (rank : 55)
Query Neighborhood Hits	1024	Target Neighborhood Hits	274	Shared Neighborhood Hits	246
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ARHG7_MOUSE
θ value	0.0252991 (rank : 342)	NC score	0.255040 (rank : 304)
Query Neighborhood Hits	1024	Target Neighborhood Hits	396	Shared Neighborhood Hits	172
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ASB5_MOUSE
θ value	0.0252991 (rank : 343)	NC score	0.489165 (rank : 125)
Query Neighborhood Hits	1024	Target Neighborhood Hits	266	Shared Neighborhood Hits	240
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CO2A1_MOUSE
θ value	0.0252991 (rank : 344)	NC score	0.187134 (rank : 408)
Query Neighborhood Hits	1024	Target Neighborhood Hits	483	Shared Neighborhood Hits	165
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CS007_HUMAN
θ value	0.0252991 (rank : 345)	NC score	0.086314 (rank : 762)
Query Neighborhood Hits	1024	Target Neighborhood Hits	401	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CTGE4_HUMAN
θ value	0.0252991 (rank : 346)	NC score	0.024933 (rank : 1410)
Query Neighborhood Hits	1024	Target Neighborhood Hits	393	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

HCN4_HUMAN
θ value	0.0252991 (rank : 347)	NC score	0.044273 (rank : 1308)
Query Neighborhood Hits	1024	Target Neighborhood Hits	303	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

MIB2_MOUSE
θ value	0.0252991 (rank : 348)	NC score	0.478916 (rank : 133)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	257
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

PELP1_HUMAN
θ value	0.0252991 (rank : 349)	NC score	0.104954 (rank : 670)
Query Neighborhood Hits	1024	Target Neighborhood Hits	596	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PHLPP_HUMAN
θ value	0.0252991 (rank : 350)	NC score	0.036996 (rank : 1344)
Query Neighborhood Hits	1024	Target Neighborhood Hits	604	Shared Neighborhood Hits	138
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

POT15_HUMAN
θ value	0.0252991 (rank : 351)	NC score	0.428084 (rank : 174)
Query Neighborhood Hits	1024	Target Neighborhood Hits	893	Shared Neighborhood Hits	289
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

SH3G3_HUMAN
θ value	0.0252991 (rank : 352)	NC score	0.257703 (rank : 300)
Query Neighborhood Hits	1024	Target Neighborhood Hits	222	Shared Neighborhood Hits	154
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SREC2_MOUSE
θ value	0.0252991 (rank : 353)	NC score	0.041914 (rank : 1321)
Query Neighborhood Hits	1024	Target Neighborhood Hits	605	Shared Neighborhood Hits	80
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TCGAP_MOUSE
θ value	0.0252991 (rank : 354)	NC score	0.160905 (rank : 473)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	200
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

XRCC1_HUMAN
θ value	0.0252991 (rank : 355)	NC score	0.070986 (rank : 882)
Query Neighborhood Hits	1024	Target Neighborhood Hits	131	Shared Neighborhood Hits	32
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZBT45_HUMAN
θ value	0.0252991 (rank : 356)	NC score	-0.001724 (rank : 1548)
Query Neighborhood Hits	1024	Target Neighborhood Hits	901	Shared Neighborhood Hits	90
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

ASB11_HUMAN
θ value	0.0330416 (rank : 357)	NC score	0.484253 (rank : 129)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB1_HUMAN
θ value	0.0330416 (rank : 358)	NC score	0.472691 (rank : 136)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB9_HUMAN
θ value	0.0330416 (rank : 359)	NC score	0.491645 (rank : 119)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	240
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

B4GN4_HUMAN
θ value	0.0330416 (rank : 360)	NC score	0.042185 (rank : 1318)
Query Neighborhood Hits	1024	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

CDN2C_MOUSE
θ value	0.0330416 (rank : 361)	NC score	0.516885 (rank : 69)
Query Neighborhood Hits	1024	Target Neighborhood Hits	270	Shared Neighborhood Hits	243
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CO9A2_HUMAN
θ value	0.0330416 (rank : 362)	NC score	0.166569 (rank : 464)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	103
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COBA1_HUMAN
θ value	0.0330416 (rank : 363)	NC score	0.186633 (rank : 410)
Query Neighborhood Hits	1024	Target Neighborhood Hits	491	Shared Neighborhood Hits	175
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CSKI1_MOUSE
θ value	0.0330416 (rank : 364)	NC score	0.538728 (rank : 30)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1031	Shared Neighborhood Hits	538
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FMN2_HUMAN
θ value	0.0330416 (rank : 365)	NC score	0.085432 (rank : 768)
Query Neighborhood Hits	1024	Target Neighborhood Hits	484	Shared Neighborhood Hits	133
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FOXE3_HUMAN
θ value	0.0330416 (rank : 366)	NC score	0.022003 (rank : 1420)
Query Neighborhood Hits	1024	Target Neighborhood Hits	112	Shared Neighborhood Hits	28
SwissProt Accessions	Q13461, Q5SVY9, Q9NQV9	Gene names	FOXE3, FKHL12, FREAC8
Domain Architecture
Description	Forkhead box protein E3 (Forkhead-related protein FKHL12) (Forkhead- related transcription factor 8) (FREAC-8).

GNAS1_HUMAN
θ value	0.0330416 (rank : 367)	NC score	0.036560 (rank : 1345)
Query Neighborhood Hits	1024	Target Neighborhood Hits	278	Shared Neighborhood Hits	91
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GRIN1_HUMAN
θ value	0.0330416 (rank : 368)	NC score	0.195207 (rank : 390)
Query Neighborhood Hits	1024	Target Neighborhood Hits	681	Shared Neighborhood Hits	242
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

K1688_MOUSE
θ value	0.0330416 (rank : 369)	NC score	0.064255 (rank : 961)
Query Neighborhood Hits	1024	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1802_MOUSE
θ value	0.0330416 (rank : 370)	NC score	0.161802 (rank : 472)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1596	Shared Neighborhood Hits	353
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NOTC2_HUMAN
θ value	0.0330416 (rank : 371)	NC score	0.256670 (rank : 303)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1113	Shared Neighborhood Hits	391
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PACN3_HUMAN
θ value	0.0330416 (rank : 372)	NC score	0.233091 (rank : 340)
Query Neighborhood Hits	1024	Target Neighborhood Hits	385	Shared Neighborhood Hits	163
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

RHG04_HUMAN
θ value	0.0330416 (rank : 373)	NC score	0.172515 (rank : 447)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	148
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RN5A_MOUSE
θ value	0.0330416 (rank : 374)	NC score	0.464158 (rank : 146)
Query Neighborhood Hits	1024	Target Neighborhood Hits	899	Shared Neighborhood Hits	304
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

SYN1_HUMAN
θ value	0.0330416 (rank : 375)	NC score	0.112938 (rank : 626)
Query Neighborhood Hits	1024	Target Neighborhood Hits	419	Shared Neighborhood Hits	164
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TEC_MOUSE
θ value	0.0330416 (rank : 376)	NC score	0.097602 (rank : 709)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1006	Shared Neighborhood Hits	169
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

ABTB2_MOUSE
θ value	0.0431538 (rank : 377)	NC score	0.356796 (rank : 215)
Query Neighborhood Hits	1024	Target Neighborhood Hits	414	Shared Neighborhood Hits	220
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ALEX_HUMAN
θ value	0.0431538 (rank : 378)	NC score	0.131361 (rank : 556)
Query Neighborhood Hits	1024	Target Neighborhood Hits	361	Shared Neighborhood Hits	148
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ANR26_HUMAN
θ value	0.0431538 (rank : 379)	NC score	0.264411 (rank : 288)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1614	Shared Neighborhood Hits	321
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ARHG4_HUMAN
θ value	0.0431538 (rank : 380)	NC score	0.210856 (rank : 368)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

BAT4_HUMAN
θ value	0.0431538 (rank : 381)	NC score	0.253383 (rank : 308)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	104
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CD2L7_HUMAN
θ value	0.0431538 (rank : 382)	NC score	0.047923 (rank : 1299)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1275	Shared Neighborhood Hits	188
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CIC_HUMAN
θ value	0.0431538 (rank : 383)	NC score	0.154005 (rank : 492)
Query Neighborhood Hits	1024	Target Neighborhood Hits	992	Shared Neighborhood Hits	330
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FOXN4_HUMAN
θ value	0.0431538 (rank : 384)	NC score	0.048262 (rank : 1297)
Query Neighborhood Hits	1024	Target Neighborhood Hits	248	Shared Neighborhood Hits	93
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

HXD11_MOUSE
θ value	0.0431538 (rank : 385)	NC score	0.010867 (rank : 1500)
Query Neighborhood Hits	1024	Target Neighborhood Hits	376	Shared Neighborhood Hits	33
SwissProt Accessions	P23813	Gene names	Hoxd11, Hox-4.6, Hoxd-11
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4.6) (Hox-5.5).

IKBB_MOUSE
θ value	0.0431538 (rank : 386)	NC score	0.473466 (rank : 135)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	246
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

MAST3_HUMAN
θ value	0.0431538 (rank : 387)	NC score	0.030607 (rank : 1377)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1128	Shared Neighborhood Hits	145
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

NEBL_HUMAN
θ value	0.0431538 (rank : 388)	NC score	0.188848 (rank : 405)
Query Neighborhood Hits	1024	Target Neighborhood Hits	457	Shared Neighborhood Hits	158
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

PACN2_HUMAN
θ value	0.0431538 (rank : 389)	NC score	0.252611 (rank : 310)
Query Neighborhood Hits	1024	Target Neighborhood Hits	339	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PKHA4_HUMAN
θ value	0.0431538 (rank : 390)	NC score	0.083272 (rank : 785)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

POT14_HUMAN
θ value	0.0431538 (rank : 391)	NC score	0.423266 (rank : 177)
Query Neighborhood Hits	1024	Target Neighborhood Hits	403	Shared Neighborhood Hits	260
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

TARSH_HUMAN
θ value	0.0431538 (rank : 392)	NC score	0.170869 (rank : 451)
Query Neighborhood Hits	1024	Target Neighborhood Hits	768	Shared Neighborhood Hits	255
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

WASP_HUMAN
θ value	0.0431538 (rank : 393)	NC score	0.095235 (rank : 719)
Query Neighborhood Hits	1024	Target Neighborhood Hits	195	Shared Neighborhood Hits	91
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

ZDHC8_HUMAN
θ value	0.0431538 (rank : 394)	NC score	0.069385 (rank : 903)
Query Neighborhood Hits	1024	Target Neighborhood Hits	234	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ZN592_HUMAN
θ value	0.0431538 (rank : 395)	NC score	-0.003971 (rank : 1550)
Query Neighborhood Hits	1024	Target Neighborhood Hits	762	Shared Neighborhood Hits	41
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

A20A2_HUMAN
θ value	0.0563607 (rank : 396)	NC score	0.392635 (rank : 189)
Query Neighborhood Hits	1024	Target Neighborhood Hits	716	Shared Neighborhood Hits	259
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ABTB2_HUMAN
θ value	0.0563607 (rank : 397)	NC score	0.367377 (rank : 206)
Query Neighborhood Hits	1024	Target Neighborhood Hits	391	Shared Neighborhood Hits	222
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

AN13C_HUMAN
θ value	0.0563607 (rank : 398)	NC score	0.334400 (rank : 229)
Query Neighborhood Hits	1024	Target Neighborhood Hits	241	Shared Neighborhood Hits	223
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13C_MOUSE
θ value	0.0563607 (rank : 399)	NC score	0.327248 (rank : 231)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	220
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANR16_HUMAN
θ value	0.0563607 (rank : 400)	NC score	0.523561 (rank : 57)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	253
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR21_HUMAN
θ value	0.0563607 (rank : 401)	NC score	0.427439 (rank : 176)
Query Neighborhood Hits	1024	Target Neighborhood Hits	864	Shared Neighborhood Hits	285
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR26_MOUSE
θ value	0.0563607 (rank : 402)	NC score	0.276507 (rank : 276)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1554	Shared Neighborhood Hits	325
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB16_MOUSE
θ value	0.0563607 (rank : 403)	NC score	0.501906 (rank : 101)
Query Neighborhood Hits	1024	Target Neighborhood Hits	306	Shared Neighborhood Hits	253
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASZ1_HUMAN
θ value	0.0563607 (rank : 404)	NC score	0.491745 (rank : 118)
Query Neighborhood Hits	1024	Target Neighborhood Hits	341	Shared Neighborhood Hits	248
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CEL_HUMAN
θ value	0.0563607 (rank : 405)	NC score	0.185695 (rank : 413)
Query Neighborhood Hits	1024	Target Neighborhood Hits	896	Shared Neighborhood Hits	364
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CENB1_HUMAN
θ value	0.0563607 (rank : 406)	NC score	0.376522 (rank : 197)
Query Neighborhood Hits	1024	Target Neighborhood Hits	383	Shared Neighborhood Hits	254
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CO4A1_MOUSE
θ value	0.0563607 (rank : 407)	NC score	0.183646 (rank : 423)
Query Neighborhood Hits	1024	Target Neighborhood Hits	450	Shared Neighborhood Hits	173
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO7A1_HUMAN
θ value	0.0563607 (rank : 408)	NC score	0.156715 (rank : 488)
Query Neighborhood Hits	1024	Target Neighborhood Hits	807	Shared Neighborhood Hits	199
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO8A1_MOUSE
θ value	0.0563607 (rank : 409)	NC score	0.150169 (rank : 499)
Query Neighborhood Hits	1024	Target Neighborhood Hits	251	Shared Neighborhood Hits	108
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

CT086_HUMAN
θ value	0.0563607 (rank : 410)	NC score	0.520228 (rank : 65)
Query Neighborhood Hits	1024	Target Neighborhood Hits	277	Shared Neighborhood Hits	247
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

GABP2_MOUSE
θ value	0.0563607 (rank : 411)	NC score	0.512192 (rank : 81)
Query Neighborhood Hits	1024	Target Neighborhood Hits	429	Shared Neighborhood Hits	265
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

IKBB_HUMAN
θ value	0.0563607 (rank : 412)	NC score	0.469300 (rank : 141)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	252
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

LDB3_HUMAN
θ value	0.0563607 (rank : 413)	NC score	0.049446 (rank : 1290)
Query Neighborhood Hits	1024	Target Neighborhood Hits	497	Shared Neighborhood Hits	114
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

M3K10_HUMAN
θ value	0.0563607 (rank : 414)	NC score	0.102932 (rank : 679)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1071	Shared Neighborhood Hits	202
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

PEX13_MOUSE
θ value	0.0563607 (rank : 415)	NC score	0.213579 (rank : 362)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PRRT1_MOUSE
θ value	0.0563607 (rank : 416)	NC score	0.071116 (rank : 880)
Query Neighborhood Hits	1024	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PSL1_HUMAN
θ value	0.0563607 (rank : 417)	NC score	0.150518 (rank : 497)
Query Neighborhood Hits	1024	Target Neighborhood Hits	650	Shared Neighborhood Hits	281
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RUSC1_HUMAN
θ value	0.0563607 (rank : 418)	NC score	0.189303 (rank : 404)
Query Neighborhood Hits	1024	Target Neighborhood Hits	226	Shared Neighborhood Hits	147
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SON_HUMAN
θ value	0.0563607 (rank : 419)	NC score	0.259522 (rank : 294)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1568	Shared Neighborhood Hits	456
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPEG_MOUSE
θ value	0.0563607 (rank : 420)	NC score	0.062935 (rank : 977)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1959	Shared Neighborhood Hits	344
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SREC2_HUMAN
θ value	0.0563607 (rank : 421)	NC score	0.046268 (rank : 1303)
Query Neighborhood Hits	1024	Target Neighborhood Hits	645	Shared Neighborhood Hits	90
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ZIM10_HUMAN
θ value	0.0563607 (rank : 422)	NC score	0.168941 (rank : 455)
Query Neighborhood Hits	1024	Target Neighborhood Hits	577	Shared Neighborhood Hits	270
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

AN36A_HUMAN
θ value	0.0736092 (rank : 423)	NC score	0.452352 (rank : 161)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	248
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ASB10_HUMAN
θ value	0.0736092 (rank : 424)	NC score	0.511606 (rank : 83)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	252
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB9_MOUSE
θ value	0.0736092 (rank : 425)	NC score	0.480171 (rank : 131)
Query Neighborhood Hits	1024	Target Neighborhood Hits	257	Shared Neighborhood Hits	232
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

BAT4_MOUSE
θ value	0.0736092 (rank : 426)	NC score	0.246847 (rank : 319)
Query Neighborhood Hits	1024	Target Neighborhood Hits	171	Shared Neighborhood Hits	119
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CIC_MOUSE
θ value	0.0736092 (rank : 427)	NC score	0.114637 (rank : 616)
Query Neighborhood Hits	1024	Target Neighborhood Hits	742	Shared Neighborhood Hits	258
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

COAA1_MOUSE
θ value	0.0736092 (rank : 428)	NC score	0.160470 (rank : 475)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	114
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

DDEF2_HUMAN
θ value	0.0736092 (rank : 429)	NC score	0.361051 (rank : 212)
Query Neighborhood Hits	1024	Target Neighborhood Hits	599	Shared Neighborhood Hits	379
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ITK_HUMAN
θ value	0.0736092 (rank : 430)	NC score	0.094506 (rank : 723)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1016	Shared Neighborhood Hits	164
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

JPH2_HUMAN
θ value	0.0736092 (rank : 431)	NC score	0.133985 (rank : 545)
Query Neighborhood Hits	1024	Target Neighborhood Hits	639	Shared Neighborhood Hits	263
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

KBTB9_MOUSE
θ value	0.0736092 (rank : 432)	NC score	0.008485 (rank : 1512)
Query Neighborhood Hits	1024	Target Neighborhood Hits	197	Shared Neighborhood Hits	16
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

MILK1_HUMAN
θ value	0.0736092 (rank : 433)	NC score	0.066369 (rank : 939)
Query Neighborhood Hits	1024	Target Neighborhood Hits	427	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PACN1_HUMAN
θ value	0.0736092 (rank : 434)	NC score	0.244567 (rank : 323)
Query Neighborhood Hits	1024	Target Neighborhood Hits	320	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	0.0736092 (rank : 435)	NC score	0.244378 (rank : 324)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	159
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PCLO_MOUSE
θ value	0.0736092 (rank : 436)	NC score	0.200653 (rank : 379)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2275	Shared Neighborhood Hits	531
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SCAP_HUMAN
θ value	0.0736092 (rank : 437)	NC score	0.033543 (rank : 1364)
Query Neighborhood Hits	1024	Target Neighborhood Hits	368	Shared Neighborhood Hits	74
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SGIP1_MOUSE
θ value	0.0736092 (rank : 438)	NC score	0.095728 (rank : 718)
Query Neighborhood Hits	1024	Target Neighborhood Hits	180	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SRBP1_HUMAN
θ value	0.0736092 (rank : 439)	NC score	0.056592 (rank : 1100)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	57
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRRM2_MOUSE
θ value	0.0736092 (rank : 440)	NC score	0.151639 (rank : 495)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1470	Shared Neighborhood Hits	315
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TRPV6_MOUSE
θ value	0.0736092 (rank : 441)	NC score	0.316520 (rank : 242)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	234
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

VAV2_HUMAN
θ value	0.0736092 (rank : 442)	NC score	0.197047 (rank : 386)
Query Neighborhood Hits	1024	Target Neighborhood Hits	453	Shared Neighborhood Hits	171
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	0.0736092 (rank : 443)	NC score	0.199947 (rank : 380)
Query Neighborhood Hits	1024	Target Neighborhood Hits	456	Shared Neighborhood Hits	184
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ANRA2_MOUSE
θ value	0.0961366 (rank : 444)	NC score	0.502351 (rank : 97)
Query Neighborhood Hits	1024	Target Neighborhood Hits	287	Shared Neighborhood Hits	249
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

BSN_MOUSE
θ value	0.0961366 (rank : 445)	NC score	0.205620 (rank : 374)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2057	Shared Neighborhood Hits	501
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CO8A2_MOUSE
θ value	0.0961366 (rank : 446)	NC score	0.153299 (rank : 493)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	120
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

COAA1_HUMAN
θ value	0.0961366 (rank : 447)	NC score	0.151097 (rank : 496)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	120
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

GOGA3_HUMAN
θ value	0.0961366 (rank : 448)	NC score	0.037464 (rank : 1340)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1317	Shared Neighborhood Hits	116
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

KCNK4_HUMAN
θ value	0.0961366 (rank : 449)	NC score	0.021845 (rank : 1422)
Query Neighborhood Hits	1024	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

OSTF1_HUMAN
θ value	0.0961366 (rank : 450)	NC score	0.571625 (rank : 18)
Query Neighborhood Hits	1024	Target Neighborhood Hits	466	Shared Neighborhood Hits	382
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	0.0961366 (rank : 451)	NC score	0.578517 (rank : 17)
Query Neighborhood Hits	1024	Target Neighborhood Hits	467	Shared Neighborhood Hits	384
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

PACN2_MOUSE
θ value	0.0961366 (rank : 452)	NC score	0.247529 (rank : 317)
Query Neighborhood Hits	1024	Target Neighborhood Hits	382	Shared Neighborhood Hits	168
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PI5PA_MOUSE
θ value	0.0961366 (rank : 453)	NC score	0.093118 (rank : 732)
Query Neighborhood Hits	1024	Target Neighborhood Hits	331	Shared Neighborhood Hits	129
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RERE_MOUSE
θ value	0.0961366 (rank : 454)	NC score	0.130143 (rank : 562)
Query Neighborhood Hits	1024	Target Neighborhood Hits	785	Shared Neighborhood Hits	218
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SGIP1_HUMAN
θ value	0.0961366 (rank : 455)	NC score	0.095077 (rank : 720)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SH3G1_HUMAN
θ value	0.0961366 (rank : 456)	NC score	0.253848 (rank : 306)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	158
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

YLPM1_MOUSE
θ value	0.0961366 (rank : 457)	NC score	0.126369 (rank : 579)
Query Neighborhood Hits	1024	Target Neighborhood Hits	505	Shared Neighborhood Hits	148
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZDHC8_MOUSE
θ value	0.0961366 (rank : 458)	NC score	0.070797 (rank : 884)
Query Neighborhood Hits	1024	Target Neighborhood Hits	243	Shared Neighborhood Hits	112
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

3BP1_HUMAN
θ value	0.125558 (rank : 459)	NC score	0.087928 (rank : 752)
Query Neighborhood Hits	1024	Target Neighborhood Hits	376	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AN13A_MOUSE
θ value	0.125558 (rank : 460)	NC score	0.289483 (rank : 269)
Query Neighborhood Hits	1024	Target Neighborhood Hits	226	Shared Neighborhood Hits	207
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

CN032_HUMAN
θ value	0.125558 (rank : 461)	NC score	0.132840 (rank : 551)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	114
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CO8A2_HUMAN
θ value	0.125558 (rank : 462)	NC score	0.158477 (rank : 481)
Query Neighborhood Hits	1024	Target Neighborhood Hits	299	Shared Neighborhood Hits	133
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

COHA1_MOUSE
θ value	0.125558 (rank : 463)	NC score	0.172844 (rank : 446)
Query Neighborhood Hits	1024	Target Neighborhood Hits	414	Shared Neighborhood Hits	148
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

EPN1_HUMAN
θ value	0.125558 (rank : 464)	NC score	0.062403 (rank : 985)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

ES8L1_MOUSE
θ value	0.125558 (rank : 465)	NC score	0.132198 (rank : 554)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	93
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

FNBP2_HUMAN
θ value	0.125558 (rank : 466)	NC score	0.149821 (rank : 501)
Query Neighborhood Hits	1024	Target Neighborhood Hits	432	Shared Neighborhood Hits	162
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

HCLS1_MOUSE
θ value	0.125558 (rank : 467)	NC score	0.276713 (rank : 275)
Query Neighborhood Hits	1024	Target Neighborhood Hits	329	Shared Neighborhood Hits	209
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

MYO15_MOUSE
θ value	0.125558 (rank : 468)	NC score	0.064000 (rank : 965)
Query Neighborhood Hits	1024	Target Neighborhood Hits	467	Shared Neighborhood Hits	180
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NOTC1_MOUSE
θ value	0.125558 (rank : 469)	NC score	0.204543 (rank : 376)
Query Neighborhood Hits	1024	Target Neighborhood Hits	916	Shared Neighborhood Hits	277
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PEF1_MOUSE
θ value	0.125558 (rank : 470)	NC score	0.027054 (rank : 1398)
Query Neighborhood Hits	1024	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PHLB1_MOUSE
θ value	0.125558 (rank : 471)	NC score	0.051781 (rank : 1237)
Query Neighborhood Hits	1024	Target Neighborhood Hits	678	Shared Neighborhood Hits	110
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SFTPD_MOUSE
θ value	0.125558 (rank : 472)	NC score	0.116737 (rank : 609)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	70
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SH3G3_MOUSE
θ value	0.125558 (rank : 473)	NC score	0.259241 (rank : 297)
Query Neighborhood Hits	1024	Target Neighborhood Hits	236	Shared Neighborhood Hits	156
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SIN3A_HUMAN
θ value	0.125558 (rank : 474)	NC score	0.045500 (rank : 1305)
Query Neighborhood Hits	1024	Target Neighborhood Hits	180	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SMRC2_MOUSE
θ value	0.125558 (rank : 475)	NC score	0.071369 (rank : 877)
Query Neighborhood Hits	1024	Target Neighborhood Hits	487	Shared Neighborhood Hits	119
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

ZN207_HUMAN
θ value	0.125558 (rank : 476)	NC score	0.116807 (rank : 608)
Query Neighborhood Hits	1024	Target Neighborhood Hits	326	Shared Neighborhood Hits	82
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

AATK_HUMAN
θ value	0.163984 (rank : 477)	NC score	0.097671 (rank : 707)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1243	Shared Neighborhood Hits	284
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ANRA2_HUMAN
θ value	0.163984 (rank : 478)	NC score	0.501587 (rank : 103)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	250
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

COIA1_MOUSE
θ value	0.163984 (rank : 479)	NC score	0.164046 (rank : 466)
Query Neighborhood Hits	1024	Target Neighborhood Hits	481	Shared Neighborhood Hits	163
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

DDEF1_MOUSE
θ value	0.163984 (rank : 480)	NC score	0.307238 (rank : 253)
Query Neighborhood Hits	1024	Target Neighborhood Hits	592	Shared Neighborhood Hits	354
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_MOUSE
θ value	0.163984 (rank : 481)	NC score	0.356378 (rank : 216)
Query Neighborhood Hits	1024	Target Neighborhood Hits	625	Shared Neighborhood Hits	384
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DUS8_MOUSE
θ value	0.163984 (rank : 482)	NC score	0.026101 (rank : 1404)
Query Neighborhood Hits	1024	Target Neighborhood Hits	119	Shared Neighborhood Hits	29
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

EDA_HUMAN
θ value	0.163984 (rank : 483)	NC score	0.137604 (rank : 529)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	76
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

FMNL_HUMAN
θ value	0.163984 (rank : 484)	NC score	0.084431 (rank : 775)
Query Neighborhood Hits	1024	Target Neighborhood Hits	529	Shared Neighborhood Hits	146
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FOXN4_MOUSE
θ value	0.163984 (rank : 485)	NC score	0.033210 (rank : 1366)
Query Neighborhood Hits	1024	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

HNRPG_MOUSE
θ value	0.163984 (rank : 486)	NC score	0.021587 (rank : 1424)
Query Neighborhood Hits	1024	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	O35479	Gene names	Rbmx, Hnrnpg, Hnrpg, Rbmxp1, Rbmxrt
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein G (hnRNP G) (RNA-binding motif protein, X chromosome).

IRS2_MOUSE
θ value	0.163984 (rank : 487)	NC score	0.062325 (rank : 986)
Query Neighborhood Hits	1024	Target Neighborhood Hits	248	Shared Neighborhood Hits	79
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MAP1A_HUMAN
θ value	0.163984 (rank : 488)	NC score	0.093208 (rank : 731)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1626	Shared Neighborhood Hits	291
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MYO15_HUMAN
θ value	0.163984 (rank : 489)	NC score	0.075680 (rank : 840)
Query Neighborhood Hits	1024	Target Neighborhood Hits	671	Shared Neighborhood Hits	261
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NOTC2_MOUSE
θ value	0.163984 (rank : 490)	NC score	0.251614 (rank : 311)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1069	Shared Neighborhood Hits	364
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NPHP1_HUMAN
θ value	0.163984 (rank : 491)	NC score	0.199715 (rank : 381)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	142
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

STAM2_HUMAN
θ value	0.163984 (rank : 492)	NC score	0.242213 (rank : 328)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	176
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

TF65_HUMAN
θ value	0.163984 (rank : 493)	NC score	0.065819 (rank : 945)
Query Neighborhood Hits	1024	Target Neighborhood Hits	115	Shared Neighborhood Hits	47
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

VASP_MOUSE
θ value	0.163984 (rank : 494)	NC score	0.072551 (rank : 868)
Query Neighborhood Hits	1024	Target Neighborhood Hits	195	Shared Neighborhood Hits	73
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

YLPM1_HUMAN
θ value	0.163984 (rank : 495)	NC score	0.134046 (rank : 544)
Query Neighborhood Hits	1024	Target Neighborhood Hits	670	Shared Neighborhood Hits	210
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZIM10_MOUSE
θ value	0.163984 (rank : 496)	NC score	0.133339 (rank : 547)
Query Neighborhood Hits	1024	Target Neighborhood Hits	430	Shared Neighborhood Hits	216
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZYX_HUMAN
θ value	0.163984 (rank : 497)	NC score	0.052535 (rank : 1218)
Query Neighborhood Hits	1024	Target Neighborhood Hits	387	Shared Neighborhood Hits	93
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

ABI1_MOUSE
θ value	0.21417 (rank : 498)	NC score	0.248884 (rank : 313)
Query Neighborhood Hits	1024	Target Neighborhood Hits	246	Shared Neighborhood Hits	172
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ANR37_MOUSE
θ value	0.21417 (rank : 499)	NC score	0.462628 (rank : 149)
Query Neighborhood Hits	1024	Target Neighborhood Hits	237	Shared Neighborhood Hits	221
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

BCL9_HUMAN
θ value	0.21417 (rank : 500)	NC score	0.232309 (rank : 341)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1008	Shared Neighborhood Hits	380
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BSN_HUMAN
θ value	0.21417 (rank : 501)	NC score	0.158926 (rank : 479)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1537	Shared Neighborhood Hits	374
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CDN2C_HUMAN
θ value	0.21417 (rank : 502)	NC score	0.514344 (rank : 73)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	240
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CNOT3_MOUSE
θ value	0.21417 (rank : 503)	NC score	0.089373 (rank : 744)
Query Neighborhood Hits	1024	Target Neighborhood Hits	504	Shared Neighborhood Hits	120
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO6A2_HUMAN
θ value	0.21417 (rank : 504)	NC score	0.141050 (rank : 520)
Query Neighborhood Hits	1024	Target Neighborhood Hits	249	Shared Neighborhood Hits	96
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

GAK5_HUMAN
θ value	0.21417 (rank : 505)	NC score	0.084023 (rank : 783)
Query Neighborhood Hits	1024	Target Neighborhood Hits	429	Shared Neighborhood Hits	186
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GCNL2_HUMAN
θ value	0.21417 (rank : 506)	NC score	0.035783 (rank : 1352)
Query Neighborhood Hits	1024	Target Neighborhood Hits	159	Shared Neighborhood Hits	58
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GLI1_HUMAN
θ value	0.21417 (rank : 507)	NC score	-0.001447 (rank : 1547)
Query Neighborhood Hits	1024	Target Neighborhood Hits	828	Shared Neighborhood Hits	78
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

HXA4_HUMAN
θ value	0.21417 (rank : 508)	NC score	0.010687 (rank : 1501)
Query Neighborhood Hits	1024	Target Neighborhood Hits	370	Shared Neighborhood Hits	44
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

IKBA_MOUSE
θ value	0.21417 (rank : 509)	NC score	0.468315 (rank : 142)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

IL3RB_HUMAN
θ value	0.21417 (rank : 510)	NC score	0.042065 (rank : 1319)
Query Neighborhood Hits	1024	Target Neighborhood Hits	163	Shared Neighborhood Hits	51
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

LDB3_MOUSE
θ value	0.21417 (rank : 511)	NC score	0.048496 (rank : 1295)
Query Neighborhood Hits	1024	Target Neighborhood Hits	510	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MDC1_MOUSE
θ value	0.21417 (rank : 512)	NC score	0.183790 (rank : 422)
Query Neighborhood Hits	1024	Target Neighborhood Hits	998	Shared Neighborhood Hits	283
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NCF1_MOUSE
θ value	0.21417 (rank : 513)	NC score	0.247548 (rank : 316)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	145
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NMDE4_HUMAN
θ value	0.21417 (rank : 514)	NC score	0.018254 (rank : 1446)
Query Neighborhood Hits	1024	Target Neighborhood Hits	133	Shared Neighborhood Hits	42
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

PLXB1_HUMAN
θ value	0.21417 (rank : 515)	NC score	0.033431 (rank : 1365)
Query Neighborhood Hits	1024	Target Neighborhood Hits	360	Shared Neighborhood Hits	115
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

RREB1_HUMAN
θ value	0.21417 (rank : 516)	NC score	0.006247 (rank : 1527)
Query Neighborhood Hits	1024	Target Neighborhood Hits	879	Shared Neighborhood Hits	85
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SALL3_HUMAN
θ value	0.21417 (rank : 517)	NC score	0.009786 (rank : 1507)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1066	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

WIRE_HUMAN
θ value	0.21417 (rank : 518)	NC score	0.140512 (rank : 521)
Query Neighborhood Hits	1024	Target Neighborhood Hits	329	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

AAK1_HUMAN
θ value	0.279714 (rank : 519)	NC score	0.054012 (rank : 1176)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1077	Shared Neighborhood Hits	188
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AB1IP_MOUSE
θ value	0.279714 (rank : 520)	NC score	0.042453 (rank : 1315)
Query Neighborhood Hits	1024	Target Neighborhood Hits	181	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

AN36B_HUMAN
θ value	0.279714 (rank : 521)	NC score	0.465691 (rank : 145)
Query Neighborhood Hits	1024	Target Neighborhood Hits	294	Shared Neighborhood Hits	252
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

BAG4_HUMAN
θ value	0.279714 (rank : 522)	NC score	0.037957 (rank : 1336)
Query Neighborhood Hits	1024	Target Neighborhood Hits	96	Shared Neighborhood Hits	33
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

BHLH8_HUMAN
θ value	0.279714 (rank : 523)	NC score	0.013759 (rank : 1481)
Query Neighborhood Hits	1024	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

CDX1_HUMAN
θ value	0.279714 (rank : 524)	NC score	0.012158 (rank : 1492)
Query Neighborhood Hits	1024	Target Neighborhood Hits	382	Shared Neighborhood Hits	38
SwissProt Accessions	P47902, Q4VAU4, Q9NYK8	Gene names	CDX1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

CO9A1_MOUSE
θ value	0.279714 (rank : 525)	NC score	0.184777 (rank : 416)
Query Neighborhood Hits	1024	Target Neighborhood Hits	477	Shared Neighborhood Hits	178
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

DYN1_HUMAN
θ value	0.279714 (rank : 526)	NC score	0.029260 (rank : 1389)
Query Neighborhood Hits	1024	Target Neighborhood Hits	216	Shared Neighborhood Hits	74
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

EDA_MOUSE
θ value	0.279714 (rank : 527)	NC score	0.135588 (rank : 536)
Query Neighborhood Hits	1024	Target Neighborhood Hits	141	Shared Neighborhood Hits	75
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EMID1_MOUSE
θ value	0.279714 (rank : 528)	NC score	0.141098 (rank : 519)
Query Neighborhood Hits	1024	Target Neighborhood Hits	230	Shared Neighborhood Hits	103
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

EP300_HUMAN
θ value	0.279714 (rank : 529)	NC score	0.134445 (rank : 543)
Query Neighborhood Hits	1024	Target Neighborhood Hits	821	Shared Neighborhood Hits	290
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ERRFI_MOUSE
θ value	0.279714 (rank : 530)	NC score	0.040193 (rank : 1327)
Query Neighborhood Hits	1024	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

FANK1_HUMAN
θ value	0.279714 (rank : 531)	NC score	0.510234 (rank : 84)
Query Neighborhood Hits	1024	Target Neighborhood Hits	326	Shared Neighborhood Hits	257
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

GA2L2_MOUSE
θ value	0.279714 (rank : 532)	NC score	0.108524 (rank : 651)
Query Neighborhood Hits	1024	Target Neighborhood Hits	395	Shared Neighborhood Hits	162
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GP153_HUMAN
θ value	0.279714 (rank : 533)	NC score	0.016430 (rank : 1459)
Query Neighborhood Hits	1024	Target Neighborhood Hits	332	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

HCN2_MOUSE
θ value	0.279714 (rank : 534)	NC score	0.046310 (rank : 1302)
Query Neighborhood Hits	1024	Target Neighborhood Hits	278	Shared Neighborhood Hits	106
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

IER5_MOUSE
θ value	0.279714 (rank : 535)	NC score	0.058762 (rank : 1045)
Query Neighborhood Hits	1024	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IKBA_HUMAN
θ value	0.279714 (rank : 536)	NC score	0.474935 (rank : 134)
Query Neighborhood Hits	1024	Target Neighborhood Hits	280	Shared Neighborhood Hits	249
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

MINK1_MOUSE
θ value	0.279714 (rank : 537)	NC score	0.037863 (rank : 1337)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1451	Shared Neighborhood Hits	155
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MUCDL_MOUSE
θ value	0.279714 (rank : 538)	NC score	0.063045 (rank : 975)
Query Neighborhood Hits	1024	Target Neighborhood Hits	461	Shared Neighborhood Hits	117
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NMDE4_MOUSE
θ value	0.279714 (rank : 539)	NC score	0.021948 (rank : 1421)
Query Neighborhood Hits	1024	Target Neighborhood Hits	158	Shared Neighborhood Hits	49
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NSD1_MOUSE
θ value	0.279714 (rank : 540)	NC score	0.062861 (rank : 981)
Query Neighborhood Hits	1024	Target Neighborhood Hits	472	Shared Neighborhood Hits	103
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PLCG2_HUMAN
θ value	0.279714 (rank : 541)	NC score	0.174868 (rank : 442)
Query Neighborhood Hits	1024	Target Neighborhood Hits	280	Shared Neighborhood Hits	144
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PRR13_MOUSE
θ value	0.279714 (rank : 542)	NC score	0.105873 (rank : 664)
Query Neighborhood Hits	1024	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PTN23_MOUSE
θ value	0.279714 (rank : 543)	NC score	0.061094 (rank : 1007)
Query Neighborhood Hits	1024	Target Neighborhood Hits	726	Shared Neighborhood Hits	195
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PUNC_MOUSE
θ value	0.279714 (rank : 544)	NC score	0.016907 (rank : 1454)
Query Neighborhood Hits	1024	Target Neighborhood Hits	501	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RPB1_HUMAN
θ value	0.279714 (rank : 545)	NC score	0.088443 (rank : 750)
Query Neighborhood Hits	1024	Target Neighborhood Hits	362	Shared Neighborhood Hits	107
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.279714 (rank : 546)	NC score	0.088486 (rank : 749)
Query Neighborhood Hits	1024	Target Neighborhood Hits	363	Shared Neighborhood Hits	108
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SF3B4_HUMAN
θ value	0.279714 (rank : 547)	NC score	0.053741 (rank : 1183)
Query Neighborhood Hits	1024	Target Neighborhood Hits	445	Shared Neighborhood Hits	115
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SNX18_MOUSE
θ value	0.279714 (rank : 548)	NC score	0.133839 (rank : 546)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	116
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

TAF3_MOUSE
θ value	0.279714 (rank : 549)	NC score	0.053977 (rank : 1179)
Query Neighborhood Hits	1024	Target Neighborhood Hits	463	Shared Neighborhood Hits	61
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ABI1_HUMAN
θ value	0.365318 (rank : 550)	NC score	0.243707 (rank : 325)
Query Neighborhood Hits	1024	Target Neighborhood Hits	257	Shared Neighborhood Hits	177
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ANR42_HUMAN
θ value	0.365318 (rank : 551)	NC score	0.515853 (rank : 70)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANXA7_MOUSE
θ value	0.365318 (rank : 552)	NC score	0.038303 (rank : 1333)
Query Neighborhood Hits	1024	Target Neighborhood Hits	142	Shared Neighborhood Hits	65
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

BASP_MOUSE
θ value	0.365318 (rank : 553)	NC score	0.103086 (rank : 676)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CENG2_HUMAN
θ value	0.365318 (rank : 554)	NC score	0.230842 (rank : 342)
Query Neighborhood Hits	1024	Target Neighborhood Hits	471	Shared Neighborhood Hits	240
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

DUS8_HUMAN
θ value	0.365318 (rank : 555)	NC score	0.029219 (rank : 1390)
Query Neighborhood Hits	1024	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

ERBB2_MOUSE
θ value	0.365318 (rank : 556)	NC score	0.058884 (rank : 1043)
Query Neighborhood Hits	1024	Target Neighborhood Hits	918	Shared Neighborhood Hits	88
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

FYB_HUMAN
θ value	0.365318 (rank : 557)	NC score	0.130614 (rank : 558)
Query Neighborhood Hits	1024	Target Neighborhood Hits	379	Shared Neighborhood Hits	151
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GGN_MOUSE
θ value	0.365318 (rank : 558)	NC score	0.119219 (rank : 597)
Query Neighborhood Hits	1024	Target Neighborhood Hits	311	Shared Neighborhood Hits	117
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HIC1_MOUSE
θ value	0.365318 (rank : 559)	NC score	-0.006426 (rank : 1557)
Query Neighborhood Hits	1024	Target Neighborhood Hits	863	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

IQEC2_HUMAN
θ value	0.365318 (rank : 560)	NC score	0.049611 (rank : 1289)
Query Neighborhood Hits	1024	Target Neighborhood Hits	403	Shared Neighborhood Hits	106
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	0.365318 (rank : 561)	NC score	0.051245 (rank : 1249)
Query Neighborhood Hits	1024	Target Neighborhood Hits	417	Shared Neighborhood Hits	110
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

KBTB9_HUMAN
θ value	0.365318 (rank : 562)	NC score	0.006493 (rank : 1524)
Query Neighborhood Hits	1024	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

NCF1_HUMAN
θ value	0.365318 (rank : 563)	NC score	0.244672 (rank : 322)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	140
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

OSBL1_HUMAN
θ value	0.365318 (rank : 564)	NC score	0.401845 (rank : 185)
Query Neighborhood Hits	1024	Target Neighborhood Hits	368	Shared Neighborhood Hits	260
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
θ value	0.365318 (rank : 565)	NC score	0.392330 (rank : 190)
Query Neighborhood Hits	1024	Target Neighborhood Hits	336	Shared Neighborhood Hits	248
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

RUSC1_MOUSE
θ value	0.365318 (rank : 566)	NC score	0.163380 (rank : 469)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	131
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SDK1_HUMAN
θ value	0.365318 (rank : 567)	NC score	0.007290 (rank : 1517)
Query Neighborhood Hits	1024	Target Neighborhood Hits	511	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

STAC3_HUMAN
θ value	0.365318 (rank : 568)	NC score	0.240092 (rank : 331)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	141
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	0.365318 (rank : 569)	NC score	0.240929 (rank : 330)
Query Neighborhood Hits	1024	Target Neighborhood Hits	232	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

TBX2_HUMAN
θ value	0.365318 (rank : 570)	NC score	0.018634 (rank : 1443)
Query Neighborhood Hits	1024	Target Neighborhood Hits	195	Shared Neighborhood Hits	59
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

ULK1_HUMAN
θ value	0.365318 (rank : 571)	NC score	0.051884 (rank : 1233)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1121	Shared Neighborhood Hits	219
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

WDR33_HUMAN
θ value	0.365318 (rank : 572)	NC score	0.082221 (rank : 789)
Query Neighborhood Hits	1024	Target Neighborhood Hits	638	Shared Neighborhood Hits	156
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ZYX_MOUSE
θ value	0.365318 (rank : 573)	NC score	0.052985 (rank : 1207)
Query Neighborhood Hits	1024	Target Neighborhood Hits	347	Shared Neighborhood Hits	88
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

ACRO_HUMAN
θ value	0.47712 (rank : 574)	NC score	0.002899 (rank : 1538)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	57
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ANR38_MOUSE
θ value	0.47712 (rank : 575)	NC score	0.377251 (rank : 195)
Query Neighborhood Hits	1024	Target Neighborhood Hits	512	Shared Neighborhood Hits	253
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CDKA2_MOUSE
θ value	0.47712 (rank : 576)	NC score	0.026588 (rank : 1401)
Query Neighborhood Hits	1024	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CPY4	Gene names	Cdk2ap2, D19Ertd144e, Doc1r
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase 2-associated protein 2 (CDK2-associated protein 2) (DOC-1-related protein) (DOC-1R).

CG1_HUMAN
θ value	0.47712 (rank : 577)	NC score	0.103034 (rank : 677)
Query Neighborhood Hits	1024	Target Neighborhood Hits	222	Shared Neighborhood Hits	101
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CIZ1_HUMAN
θ value	0.47712 (rank : 578)	NC score	0.090236 (rank : 741)
Query Neighborhood Hits	1024	Target Neighborhood Hits	359	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CO4A1_HUMAN
θ value	0.47712 (rank : 579)	NC score	0.182179 (rank : 429)
Query Neighborhood Hits	1024	Target Neighborhood Hits	425	Shared Neighborhood Hits	165
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

COBA1_MOUSE
θ value	0.47712 (rank : 580)	NC score	0.183147 (rank : 426)
Query Neighborhood Hits	1024	Target Neighborhood Hits	487	Shared Neighborhood Hits	176
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

DBP_HUMAN
θ value	0.47712 (rank : 581)	NC score	0.029549 (rank : 1386)
Query Neighborhood Hits	1024	Target Neighborhood Hits	136	Shared Neighborhood Hits	37
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

EMID1_HUMAN
θ value	0.47712 (rank : 582)	NC score	0.139771 (rank : 522)
Query Neighborhood Hits	1024	Target Neighborhood Hits	215	Shared Neighborhood Hits	100
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

FARP2_HUMAN
θ value	0.47712 (rank : 583)	NC score	0.044615 (rank : 1307)
Query Neighborhood Hits	1024	Target Neighborhood Hits	240	Shared Neighborhood Hits	54
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GAB1_HUMAN
θ value	0.47712 (rank : 584)	NC score	0.056212 (rank : 1105)
Query Neighborhood Hits	1024	Target Neighborhood Hits	279	Shared Neighborhood Hits	102
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GATA4_HUMAN
θ value	0.47712 (rank : 585)	NC score	0.016001 (rank : 1463)
Query Neighborhood Hits	1024	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P43694	Gene names	GATA4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

JADE2_HUMAN
θ value	0.47712 (rank : 586)	NC score	0.024846 (rank : 1411)
Query Neighborhood Hits	1024	Target Neighborhood Hits	199	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

KLF13_MOUSE
θ value	0.47712 (rank : 587)	NC score	-0.006282 (rank : 1555)
Query Neighborhood Hits	1024	Target Neighborhood Hits	757	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

NEUR4_HUMAN
θ value	0.47712 (rank : 588)	NC score	0.018634 (rank : 1442)
Query Neighborhood Hits	1024	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWR8, Q96D64	Gene names	NEU4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4).

PHLPP_MOUSE
θ value	0.47712 (rank : 589)	NC score	0.010569 (rank : 1502)
Query Neighborhood Hits	1024	Target Neighborhood Hits	394	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PRD10_HUMAN
θ value	0.47712 (rank : 590)	NC score	-0.010268 (rank : 1564)
Query Neighborhood Hits	1024	Target Neighborhood Hits	769	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NQV6, Q9ULI9	Gene names	PRDM10, KIAA1231, PFM7
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 10 (PR domain-containing protein 10).

PRDM2_HUMAN
θ value	0.47712 (rank : 591)	NC score	0.020541 (rank : 1429)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1135	Shared Neighborhood Hits	133
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PRR12_HUMAN
θ value	0.47712 (rank : 592)	NC score	0.142001 (rank : 514)
Query Neighborhood Hits	1024	Target Neighborhood Hits	460	Shared Neighborhood Hits	159
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	0.47712 (rank : 593)	NC score	0.100645 (rank : 694)
Query Neighborhood Hits	1024	Target Neighborhood Hits	105	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RAI14_MOUSE
θ value	0.47712 (rank : 594)	NC score	0.357972 (rank : 214)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1505	Shared Neighborhood Hits	327
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RBM14_MOUSE
θ value	0.47712 (rank : 595)	NC score	0.019713 (rank : 1436)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

SHLB1_MOUSE
θ value	0.47712 (rank : 596)	NC score	0.117221 (rank : 607)
Query Neighborhood Hits	1024	Target Neighborhood Hits	101	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

TCRG1_MOUSE
θ value	0.47712 (rank : 597)	NC score	0.067603 (rank : 920)
Query Neighborhood Hits	1024	Target Neighborhood Hits	947	Shared Neighborhood Hits	139
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TTBK2_HUMAN
θ value	0.47712 (rank : 598)	NC score	0.043255 (rank : 1312)
Query Neighborhood Hits	1024	Target Neighborhood Hits	822	Shared Neighborhood Hits	95
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

TTBK2_MOUSE
θ value	0.47712 (rank : 599)	NC score	0.042391 (rank : 1317)
Query Neighborhood Hits	1024	Target Neighborhood Hits	811	Shared Neighborhood Hits	89
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

VASP_HUMAN
θ value	0.47712 (rank : 600)	NC score	0.078450 (rank : 818)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	92
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WASL_MOUSE
θ value	0.47712 (rank : 601)	NC score	0.121942 (rank : 587)
Query Neighborhood Hits	1024	Target Neighborhood Hits	339	Shared Neighborhood Hits	131
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

AN30A_HUMAN
θ value	0.62314 (rank : 602)	NC score	0.351906 (rank : 222)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1119	Shared Neighborhood Hits	300
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR18_HUMAN
θ value	0.62314 (rank : 603)	NC score	0.352413 (rank : 220)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1106	Shared Neighborhood Hits	285
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR38_HUMAN
θ value	0.62314 (rank : 604)	NC score	0.386088 (rank : 193)
Query Neighborhood Hits	1024	Target Neighborhood Hits	443	Shared Neighborhood Hits	247
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

APC_HUMAN
θ value	0.62314 (rank : 605)	NC score	0.053677 (rank : 1184)
Query Neighborhood Hits	1024	Target Neighborhood Hits	603	Shared Neighborhood Hits	108
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

CENG2_MOUSE
θ value	0.62314 (rank : 606)	NC score	0.228637 (rank : 344)
Query Neighborhood Hits	1024	Target Neighborhood Hits	463	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CMTA2_MOUSE
θ value	0.62314 (rank : 607)	NC score	0.098465 (rank : 702)
Query Neighborhood Hits	1024	Target Neighborhood Hits	216	Shared Neighborhood Hits	103
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

FOG1_HUMAN
θ value	0.62314 (rank : 608)	NC score	0.018213 (rank : 1447)
Query Neighborhood Hits	1024	Target Neighborhood Hits	981	Shared Neighborhood Hits	139
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GGN_HUMAN
θ value	0.62314 (rank : 609)	NC score	0.107369 (rank : 656)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	112
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HNRPG_HUMAN
θ value	0.62314 (rank : 610)	NC score	0.019034 (rank : 1440)
Query Neighborhood Hits	1024	Target Neighborhood Hits	245	Shared Neighborhood Hits	27
SwissProt Accessions	P38159, Q5JQ67, Q969R3	Gene names	RBMX, HNRPG, RBMXP1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein G (hnRNP G) (RNA-binding motif protein, X chromosome) (Glycoprotein p43).

IL4RA_HUMAN
θ value	0.62314 (rank : 611)	NC score	0.043817 (rank : 1310)
Query Neighborhood Hits	1024	Target Neighborhood Hits	144	Shared Neighborhood Hits	47
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

IRS1_MOUSE
θ value	0.62314 (rank : 612)	NC score	0.037541 (rank : 1339)
Query Neighborhood Hits	1024	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

MBB1A_HUMAN
θ value	0.62314 (rank : 613)	NC score	0.118607 (rank : 600)
Query Neighborhood Hits	1024	Target Neighborhood Hits	665	Shared Neighborhood Hits	207
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MILK2_HUMAN
θ value	0.62314 (rank : 614)	NC score	0.052048 (rank : 1231)
Query Neighborhood Hits	1024	Target Neighborhood Hits	457	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MLL3_HUMAN
θ value	0.62314 (rank : 615)	NC score	0.171488 (rank : 450)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1644	Shared Neighborhood Hits	379
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RXRB_MOUSE
θ value	0.62314 (rank : 616)	NC score	0.007957 (rank : 1514)
Query Neighborhood Hits	1024	Target Neighborhood Hits	230	Shared Neighborhood Hits	53
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

SIN3A_MOUSE
θ value	0.62314 (rank : 617)	NC score	0.038527 (rank : 1330)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	52
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SMRC2_HUMAN
θ value	0.62314 (rank : 618)	NC score	0.062891 (rank : 978)
Query Neighborhood Hits	1024	Target Neighborhood Hits	499	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SOX17_MOUSE
θ value	0.62314 (rank : 619)	NC score	0.031333 (rank : 1375)
Query Neighborhood Hits	1024	Target Neighborhood Hits	223	Shared Neighborhood Hits	84
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SRBS1_MOUSE
θ value	0.62314 (rank : 620)	NC score	0.246628 (rank : 320)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	203
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SYN1_MOUSE
θ value	0.62314 (rank : 621)	NC score	0.094882 (rank : 721)
Query Neighborhood Hits	1024	Target Neighborhood Hits	363	Shared Neighborhood Hits	142
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNPO_HUMAN
θ value	0.62314 (rank : 622)	NC score	0.075067 (rank : 842)
Query Neighborhood Hits	1024	Target Neighborhood Hits	281	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

T22D2_HUMAN
θ value	0.62314 (rank : 623)	NC score	0.082898 (rank : 787)
Query Neighborhood Hits	1024	Target Neighborhood Hits	250	Shared Neighborhood Hits	98
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TCRG1_HUMAN
θ value	0.62314 (rank : 624)	NC score	0.064293 (rank : 960)
Query Neighborhood Hits	1024	Target Neighborhood Hits	929	Shared Neighborhood Hits	130
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TEX14_MOUSE
θ value	0.62314 (rank : 625)	NC score	0.293616 (rank : 264)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1333	Shared Neighborhood Hits	329
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

UBP42_HUMAN
θ value	0.62314 (rank : 626)	NC score	0.055757 (rank : 1120)
Query Neighborhood Hits	1024	Target Neighborhood Hits	445	Shared Neighborhood Hits	145
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

WASF4_HUMAN
θ value	0.62314 (rank : 627)	NC score	0.094473 (rank : 725)
Query Neighborhood Hits	1024	Target Neighborhood Hits	282	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WIRE_MOUSE
θ value	0.62314 (rank : 628)	NC score	0.136367 (rank : 535)
Query Neighborhood Hits	1024	Target Neighborhood Hits	310	Shared Neighborhood Hits	136
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ANR47_MOUSE
θ value	0.813845 (rank : 629)	NC score	0.444223 (rank : 167)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	256
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB4_HUMAN
θ value	0.813845 (rank : 630)	NC score	0.463929 (rank : 147)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	245
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB7_HUMAN
θ value	0.813845 (rank : 631)	NC score	0.495832 (rank : 112)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	254
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	0.813845 (rank : 632)	NC score	0.496053 (rank : 111)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	254
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

BAT2_HUMAN
θ value	0.813845 (rank : 633)	NC score	0.175261 (rank : 441)
Query Neighborhood Hits	1024	Target Neighborhood Hits	931	Shared Neighborhood Hits	315
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BIN1_MOUSE
θ value	0.813845 (rank : 634)	NC score	0.088562 (rank : 747)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	122
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CK056_MOUSE
θ value	0.813845 (rank : 635)	NC score	0.035867 (rank : 1351)
Query Neighborhood Hits	1024	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q3U2I3, Q3TWF5, Q6P543, Q80T93, Q811J6, Q8BI34, Q8VE55	Gene names	Kiaa1759
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf56 homolog.

CLPB_HUMAN
θ value	0.813845 (rank : 636)	NC score	0.345621 (rank : 226)
Query Neighborhood Hits	1024	Target Neighborhood Hits	265	Shared Neighborhood Hits	212
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CO6A2_MOUSE
θ value	0.813845 (rank : 637)	NC score	0.137701 (rank : 528)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	94
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO9A1_HUMAN
θ value	0.813845 (rank : 638)	NC score	0.177799 (rank : 434)
Query Neighborhood Hits	1024	Target Neighborhood Hits	420	Shared Neighborhood Hits	144
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

COEA1_HUMAN
θ value	0.813845 (rank : 639)	NC score	0.102905 (rank : 680)
Query Neighborhood Hits	1024	Target Neighborhood Hits	427	Shared Neighborhood Hits	114
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

DBNL_HUMAN
θ value	0.813845 (rank : 640)	NC score	0.197802 (rank : 384)
Query Neighborhood Hits	1024	Target Neighborhood Hits	244	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	0.813845 (rank : 641)	NC score	0.198268 (rank : 382)
Query Neighborhood Hits	1024	Target Neighborhood Hits	306	Shared Neighborhood Hits	146
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

ELN_MOUSE
θ value	0.813845 (rank : 642)	NC score	0.118558 (rank : 601)
Query Neighborhood Hits	1024	Target Neighborhood Hits	105	Shared Neighborhood Hits	53
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

FOG2_MOUSE
θ value	0.813845 (rank : 643)	NC score	0.001187 (rank : 1544)
Query Neighborhood Hits	1024	Target Neighborhood Hits	714	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

GAK6_HUMAN
θ value	0.813845 (rank : 644)	NC score	0.079467 (rank : 812)
Query Neighborhood Hits	1024	Target Neighborhood Hits	392	Shared Neighborhood Hits	170
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

IRX5_HUMAN
θ value	0.813845 (rank : 645)	NC score	0.036038 (rank : 1349)
Query Neighborhood Hits	1024	Target Neighborhood Hits	362	Shared Neighborhood Hits	68
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

JPH2_MOUSE
θ value	0.813845 (rank : 646)	NC score	0.055036 (rank : 1145)
Query Neighborhood Hits	1024	Target Neighborhood Hits	279	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

KCNC3_HUMAN
θ value	0.813845 (rank : 647)	NC score	0.010522 (rank : 1504)
Query Neighborhood Hits	1024	Target Neighborhood Hits	256	Shared Neighborhood Hits	65
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KLF2_HUMAN
θ value	0.813845 (rank : 648)	NC score	-0.004740 (rank : 1552)
Query Neighborhood Hits	1024	Target Neighborhood Hits	755	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

LIPS_HUMAN
θ value	0.813845 (rank : 649)	NC score	0.054271 (rank : 1169)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	89
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MKL1_MOUSE
θ value	0.813845 (rank : 650)	NC score	0.116423 (rank : 611)
Query Neighborhood Hits	1024	Target Neighborhood Hits	667	Shared Neighborhood Hits	249
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

PAPOA_MOUSE
θ value	0.813845 (rank : 651)	NC score	0.020512 (rank : 1430)
Query Neighborhood Hits	1024	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

PI5PA_HUMAN
θ value	0.813845 (rank : 652)	NC score	0.172191 (rank : 448)
Query Neighborhood Hits	1024	Target Neighborhood Hits	749	Shared Neighborhood Hits	316
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PLS3_MOUSE
θ value	0.813845 (rank : 653)	NC score	0.024404 (rank : 1413)
Query Neighborhood Hits	1024	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JIZ9	Gene names	Plscr3
Domain Architecture
Description	Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3).

PO121_MOUSE
θ value	0.813845 (rank : 654)	NC score	0.084075 (rank : 780)
Query Neighborhood Hits	1024	Target Neighborhood Hits	345	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RAI14_HUMAN
θ value	0.813845 (rank : 655)	NC score	0.370763 (rank : 201)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1367	Shared Neighborhood Hits	316
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RFXK_MOUSE
θ value	0.813845 (rank : 656)	NC score	0.490525 (rank : 120)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	247
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

SASH1_HUMAN
θ value	0.813845 (rank : 657)	NC score	0.071007 (rank : 881)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	125
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SFR15_HUMAN
θ value	0.813845 (rank : 658)	NC score	0.087766 (rank : 755)
Query Neighborhood Hits	1024	Target Neighborhood Hits	368	Shared Neighborhood Hits	113
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SNCAP_HUMAN
θ value	0.813845 (rank : 659)	NC score	0.448023 (rank : 166)
Query Neighborhood Hits	1024	Target Neighborhood Hits	313	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

SRBS1_HUMAN
θ value	0.813845 (rank : 660)	NC score	0.241487 (rank : 329)
Query Neighborhood Hits	1024	Target Neighborhood Hits	396	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	0.813845 (rank : 661)	NC score	0.253166 (rank : 309)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	166
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	0.813845 (rank : 662)	NC score	0.257211 (rank : 301)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	175
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

UB7I1_MOUSE
θ value	0.813845 (rank : 663)	NC score	0.049109 (rank : 1291)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

AN13A_HUMAN
θ value	1.06291 (rank : 664)	NC score	0.299175 (rank : 259)
Query Neighborhood Hits	1024	Target Neighborhood Hits	243	Shared Neighborhood Hits	209
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANKF1_HUMAN
θ value	1.06291 (rank : 665)	NC score	0.130404 (rank : 559)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKY2_HUMAN
θ value	1.06291 (rank : 666)	NC score	0.433829 (rank : 172)
Query Neighborhood Hits	1024	Target Neighborhood Hits	306	Shared Neighborhood Hits	238
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANX11_HUMAN
θ value	1.06291 (rank : 667)	NC score	0.028265 (rank : 1393)
Query Neighborhood Hits	1024	Target Neighborhood Hits	192	Shared Neighborhood Hits	75
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

ANX11_MOUSE
θ value	1.06291 (rank : 668)	NC score	0.032817 (rank : 1369)
Query Neighborhood Hits	1024	Target Neighborhood Hits	200	Shared Neighborhood Hits	78
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

ATN1_HUMAN
θ value	1.06291 (rank : 669)	NC score	0.134950 (rank : 540)
Query Neighborhood Hits	1024	Target Neighborhood Hits	676	Shared Neighborhood Hits	183
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAZ2A_MOUSE
θ value	1.06291 (rank : 670)	NC score	0.080151 (rank : 809)
Query Neighborhood Hits	1024	Target Neighborhood Hits	744	Shared Neighborhood Hits	193
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BLNK_MOUSE
θ value	1.06291 (rank : 671)	NC score	0.105402 (rank : 667)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CEND3_HUMAN
θ value	1.06291 (rank : 672)	NC score	0.066581 (rank : 935)
Query Neighborhood Hits	1024	Target Neighborhood Hits	275	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CO039_MOUSE
θ value	1.06291 (rank : 673)	NC score	0.143132 (rank : 511)
Query Neighborhood Hits	1024	Target Neighborhood Hits	445	Shared Neighborhood Hits	190
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

DIDO1_HUMAN
θ value	1.06291 (rank : 674)	NC score	0.209382 (rank : 370)
Query Neighborhood Hits	1024	Target Neighborhood Hits	960	Shared Neighborhood Hits	304
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EMID2_HUMAN
θ value	1.06291 (rank : 675)	NC score	0.138124 (rank : 527)
Query Neighborhood Hits	1024	Target Neighborhood Hits	226	Shared Neighborhood Hits	105
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

ERF_MOUSE
θ value	1.06291 (rank : 676)	NC score	0.020127 (rank : 1433)
Query Neighborhood Hits	1024	Target Neighborhood Hits	160	Shared Neighborhood Hits	50
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

FANK1_MOUSE
θ value	1.06291 (rank : 677)	NC score	0.508374 (rank : 90)
Query Neighborhood Hits	1024	Target Neighborhood Hits	325	Shared Neighborhood Hits	258
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

FGD1_HUMAN
θ value	1.06291 (rank : 678)	NC score	0.074435 (rank : 850)
Query Neighborhood Hits	1024	Target Neighborhood Hits	367	Shared Neighborhood Hits	129
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

GAK11_HUMAN
θ value	1.06291 (rank : 679)	NC score	0.080333 (rank : 803)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	177
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	1.06291 (rank : 680)	NC score	0.073986 (rank : 855)
Query Neighborhood Hits	1024	Target Neighborhood Hits	374	Shared Neighborhood Hits	165
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
θ value	1.06291 (rank : 681)	NC score	0.061638 (rank : 995)
Query Neighborhood Hits	1024	Target Neighborhood Hits	268	Shared Neighborhood Hits	116
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	1.06291 (rank : 682)	NC score	0.080165 (rank : 808)
Query Neighborhood Hits	1024	Target Neighborhood Hits	406	Shared Neighborhood Hits	177
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	1.06291 (rank : 683)	NC score	0.080328 (rank : 805)
Query Neighborhood Hits	1024	Target Neighborhood Hits	415	Shared Neighborhood Hits	179
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GATA4_MOUSE
θ value	1.06291 (rank : 684)	NC score	0.015222 (rank : 1469)
Query Neighborhood Hits	1024	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	Q08369, P97491, Q9QZK4	Gene names	Gata4, Gata-4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

IF35_MOUSE
θ value	1.06291 (rank : 685)	NC score	0.052775 (rank : 1210)
Query Neighborhood Hits	1024	Target Neighborhood Hits	210	Shared Neighborhood Hits	66
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IRX1_HUMAN
θ value	1.06291 (rank : 686)	NC score	0.030203 (rank : 1383)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	32
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

KLF13_HUMAN
θ value	1.06291 (rank : 687)	NC score	-0.007121 (rank : 1559)
Query Neighborhood Hits	1024	Target Neighborhood Hits	739	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

LASP1_HUMAN
θ value	1.06291 (rank : 688)	NC score	0.192307 (rank : 397)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	143
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	1.06291 (rank : 689)	NC score	0.190346 (rank : 401)
Query Neighborhood Hits	1024	Target Neighborhood Hits	297	Shared Neighborhood Hits	143
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MAGD1_HUMAN
θ value	1.06291 (rank : 690)	NC score	0.022091 (rank : 1419)
Query Neighborhood Hits	1024	Target Neighborhood Hits	130	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

MMP9_MOUSE
θ value	1.06291 (rank : 691)	NC score	0.012164 (rank : 1491)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	36
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

MYLK_HUMAN
θ value	1.06291 (rank : 692)	NC score	0.030604 (rank : 1378)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1328	Shared Neighborhood Hits	108
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NCOR2_MOUSE
θ value	1.06291 (rank : 693)	NC score	0.068231 (rank : 913)
Query Neighborhood Hits	1024	Target Neighborhood Hits	790	Shared Neighborhood Hits	169
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NFM_HUMAN
θ value	1.06291 (rank : 694)	NC score	0.026057 (rank : 1405)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1328	Shared Neighborhood Hits	156
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NU214_HUMAN
θ value	1.06291 (rank : 695)	NC score	0.094490 (rank : 724)
Query Neighborhood Hits	1024	Target Neighborhood Hits	657	Shared Neighborhood Hits	148
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PI51C_HUMAN
θ value	1.06291 (rank : 696)	NC score	0.012794 (rank : 1487)
Query Neighborhood Hits	1024	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PRCC_HUMAN
θ value	1.06291 (rank : 697)	NC score	0.069410 (rank : 902)
Query Neighborhood Hits	1024	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

RBM14_HUMAN
θ value	1.06291 (rank : 698)	NC score	0.017930 (rank : 1449)
Query Neighborhood Hits	1024	Target Neighborhood Hits	213	Shared Neighborhood Hits	20
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

RIMB1_HUMAN
θ value	1.06291 (rank : 699)	NC score	0.137033 (rank : 532)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1479	Shared Neighborhood Hits	331
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RSMB_HUMAN
θ value	1.06291 (rank : 700)	NC score	0.056839 (rank : 1095)
Query Neighborhood Hits	1024	Target Neighborhood Hits	117	Shared Neighborhood Hits	49
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

RSMB_MOUSE
θ value	1.06291 (rank : 701)	NC score	0.053958 (rank : 1180)
Query Neighborhood Hits	1024	Target Neighborhood Hits	93	Shared Neighborhood Hits	41
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

SNX18_HUMAN
θ value	1.06291 (rank : 702)	NC score	0.129507 (rank : 564)
Query Neighborhood Hits	1024	Target Neighborhood Hits	207	Shared Neighborhood Hits	119
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

TLE4_MOUSE
θ value	1.06291 (rank : 703)	NC score	0.019137 (rank : 1438)
Query Neighborhood Hits	1024	Target Neighborhood Hits	482	Shared Neighborhood Hits	113
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

US6NL_MOUSE
θ value	1.06291 (rank : 704)	NC score	0.026138 (rank : 1403)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

BAT2_MOUSE
θ value	1.38821 (rank : 705)	NC score	0.164534 (rank : 465)
Query Neighborhood Hits	1024	Target Neighborhood Hits	947	Shared Neighborhood Hits	337
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BRSK1_HUMAN
θ value	1.38821 (rank : 706)	NC score	0.034796 (rank : 1359)
Query Neighborhood Hits	1024	Target Neighborhood Hits	942	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

CLPB_MOUSE
θ value	1.38821 (rank : 707)	NC score	0.410493 (rank : 182)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	238
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CNOT3_HUMAN
θ value	1.38821 (rank : 708)	NC score	0.074337 (rank : 851)
Query Neighborhood Hits	1024	Target Neighborhood Hits	425	Shared Neighborhood Hits	89
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

COKA1_HUMAN
θ value	1.38821 (rank : 709)	NC score	0.096667 (rank : 714)
Query Neighborhood Hits	1024	Target Neighborhood Hits	403	Shared Neighborhood Hits	126
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

DAAM2_HUMAN
θ value	1.38821 (rank : 710)	NC score	0.028090 (rank : 1394)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	59
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DOK2_MOUSE
θ value	1.38821 (rank : 711)	NC score	0.065809 (rank : 946)
Query Neighborhood Hits	1024	Target Neighborhood Hits	244	Shared Neighborhood Hits	123
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

ES8L3_HUMAN
θ value	1.38821 (rank : 712)	NC score	0.146333 (rank : 506)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	129
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

EVX1_HUMAN
θ value	1.38821 (rank : 713)	NC score	0.002204 (rank : 1540)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	17
SwissProt Accessions	P49640	Gene names	EVX1
Domain Architecture
Description	Homeobox even-skipped homolog protein 1 (EVX-1).

GNAS1_MOUSE
θ value	1.38821 (rank : 714)	NC score	0.093045 (rank : 733)
Query Neighborhood Hits	1024	Target Neighborhood Hits	651	Shared Neighborhood Hits	252
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

HXD1_MOUSE
θ value	1.38821 (rank : 715)	NC score	0.008730 (rank : 1510)
Query Neighborhood Hits	1024	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

MAML1_MOUSE
θ value	1.38821 (rank : 716)	NC score	0.076239 (rank : 834)
Query Neighborhood Hits	1024	Target Neighborhood Hits	279	Shared Neighborhood Hits	119
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MAST4_HUMAN
θ value	1.38821 (rank : 717)	NC score	0.061788 (rank : 991)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1804	Shared Neighborhood Hits	354
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MK15_HUMAN
θ value	1.38821 (rank : 718)	NC score	0.038120 (rank : 1335)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1038	Shared Neighborhood Hits	187
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

MUCDL_HUMAN
θ value	1.38821 (rank : 719)	NC score	0.146570 (rank : 504)
Query Neighborhood Hits	1024	Target Neighborhood Hits	777	Shared Neighborhood Hits	263
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCOR1_MOUSE
θ value	1.38821 (rank : 720)	NC score	0.043462 (rank : 1311)
Query Neighborhood Hits	1024	Target Neighborhood Hits	521	Shared Neighborhood Hits	91
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PCQAP_MOUSE
θ value	1.38821 (rank : 721)	NC score	0.068986 (rank : 905)
Query Neighborhood Hits	1024	Target Neighborhood Hits	506	Shared Neighborhood Hits	111
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PHC2_HUMAN
θ value	1.38821 (rank : 722)	NC score	0.093331 (rank : 730)
Query Neighborhood Hits	1024	Target Neighborhood Hits	388	Shared Neighborhood Hits	156
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

RAIN_HUMAN
θ value	1.38821 (rank : 723)	NC score	0.012010 (rank : 1493)
Query Neighborhood Hits	1024	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RANB3_HUMAN
θ value	1.38821 (rank : 724)	NC score	0.029394 (rank : 1388)
Query Neighborhood Hits	1024	Target Neighborhood Hits	117	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

SEPT9_HUMAN
θ value	1.38821 (rank : 725)	NC score	0.079702 (rank : 810)
Query Neighborhood Hits	1024	Target Neighborhood Hits	706	Shared Neighborhood Hits	222
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SF01_HUMAN
θ value	1.38821 (rank : 726)	NC score	0.081373 (rank : 794)
Query Neighborhood Hits	1024	Target Neighborhood Hits	287	Shared Neighborhood Hits	115
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SFTPD_HUMAN
θ value	1.38821 (rank : 727)	NC score	0.119871 (rank : 594)
Query Neighborhood Hits	1024	Target Neighborhood Hits	238	Shared Neighborhood Hits	78
SwissProt Accessions	P35247, Q86YK9, Q9UCJ2, Q9UCJ3	Gene names	SFTPD, PSPD, SFTP4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SMCA2_HUMAN
θ value	1.38821 (rank : 728)	NC score	0.025989 (rank : 1406)
Query Neighborhood Hits	1024	Target Neighborhood Hits	503	Shared Neighborhood Hits	100
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMRD3_HUMAN
θ value	1.38821 (rank : 729)	NC score	0.014360 (rank : 1473)
Query Neighborhood Hits	1024	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q6STE5, Q75MJ2, Q75MR8, Q92926, Q9BUH1	Gene names	SMARCD3, BAF60C
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C).

SPTA1_MOUSE
θ value	1.38821 (rank : 730)	NC score	0.106129 (rank : 662)
Query Neighborhood Hits	1024	Target Neighborhood Hits	675	Shared Neighborhood Hits	160
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TNR6A_HUMAN
θ value	1.38821 (rank : 731)	NC score	0.050940 (rank : 1257)
Query Neighborhood Hits	1024	Target Neighborhood Hits	343	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

TRPV5_MOUSE
θ value	1.38821 (rank : 732)	NC score	0.281925 (rank : 273)
Query Neighborhood Hits	1024	Target Neighborhood Hits	278	Shared Neighborhood Hits	227
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TSC1_HUMAN
θ value	1.38821 (rank : 733)	NC score	0.037319 (rank : 1341)
Query Neighborhood Hits	1024	Target Neighborhood Hits	765	Shared Neighborhood Hits	110
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

UBP51_HUMAN
θ value	1.38821 (rank : 734)	NC score	0.012337 (rank : 1489)
Query Neighborhood Hits	1024	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

ABI3_MOUSE
θ value	1.81305 (rank : 735)	NC score	0.211127 (rank : 367)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ANKY2_MOUSE
θ value	1.81305 (rank : 736)	NC score	0.421117 (rank : 178)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	237
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

BRPF1_HUMAN
θ value	1.81305 (rank : 737)	NC score	0.018096 (rank : 1448)
Query Neighborhood Hits	1024	Target Neighborhood Hits	259	Shared Neighborhood Hits	41
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

GIT1_HUMAN
θ value	1.81305 (rank : 738)	NC score	0.308696 (rank : 251)
Query Neighborhood Hits	1024	Target Neighborhood Hits	336	Shared Neighborhood Hits	237
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	1.81305 (rank : 739)	NC score	0.308603 (rank : 252)
Query Neighborhood Hits	1024	Target Neighborhood Hits	341	Shared Neighborhood Hits	236
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GLIS3_MOUSE
θ value	1.81305 (rank : 740)	NC score	-0.001964 (rank : 1549)
Query Neighborhood Hits	1024	Target Neighborhood Hits	861	Shared Neighborhood Hits	104
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

IF4G1_HUMAN
θ value	1.81305 (rank : 741)	NC score	0.047477 (rank : 1300)
Query Neighborhood Hits	1024	Target Neighborhood Hits	347	Shared Neighborhood Hits	108
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

LOXL1_MOUSE
θ value	1.81305 (rank : 742)	NC score	0.016918 (rank : 1453)
Query Neighborhood Hits	1024	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

LTB1L_HUMAN
θ value	1.81305 (rank : 743)	NC score	0.025891 (rank : 1408)
Query Neighborhood Hits	1024	Target Neighborhood Hits	553	Shared Neighborhood Hits	56
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	1.81305 (rank : 744)	NC score	0.024464 (rank : 1412)
Query Neighborhood Hits	1024	Target Neighborhood Hits	502	Shared Neighborhood Hits	42
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PDCD7_HUMAN
θ value	1.81305 (rank : 745)	NC score	0.060753 (rank : 1013)
Query Neighborhood Hits	1024	Target Neighborhood Hits	255	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PDCD7_MOUSE
θ value	1.81305 (rank : 746)	NC score	0.048888 (rank : 1293)
Query Neighborhood Hits	1024	Target Neighborhood Hits	214	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PHF8_MOUSE
θ value	1.81305 (rank : 747)	NC score	0.008639 (rank : 1511)
Query Neighborhood Hits	1024	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHX2B_HUMAN
θ value	1.81305 (rank : 748)	NC score	0.014108 (rank : 1477)
Query Neighborhood Hits	1024	Target Neighborhood Hits	407	Shared Neighborhood Hits	53
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
θ value	1.81305 (rank : 749)	NC score	0.014108 (rank : 1478)
Query Neighborhood Hits	1024	Target Neighborhood Hits	407	Shared Neighborhood Hits	53
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

POT22_HUMAN
θ value	1.81305 (rank : 750)	NC score	0.391330 (rank : 191)
Query Neighborhood Hits	1024	Target Neighborhood Hits	266	Shared Neighborhood Hits	241
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

PRRT3_HUMAN
θ value	1.81305 (rank : 751)	NC score	0.274797 (rank : 280)
Query Neighborhood Hits	1024	Target Neighborhood Hits	998	Shared Neighborhood Hits	412
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RIMB2_HUMAN
θ value	1.81305 (rank : 752)	NC score	0.141510 (rank : 517)
Query Neighborhood Hits	1024	Target Neighborhood Hits	263	Shared Neighborhood Hits	120
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SEM6C_HUMAN
θ value	1.81305 (rank : 753)	NC score	0.006478 (rank : 1525)
Query Neighborhood Hits	1024	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SON_MOUSE
θ value	1.81305 (rank : 754)	NC score	0.190707 (rank : 399)
Query Neighborhood Hits	1024	Target Neighborhood Hits	957	Shared Neighborhood Hits	291
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SOS1_HUMAN
θ value	1.81305 (rank : 755)	NC score	0.046515 (rank : 1301)
Query Neighborhood Hits	1024	Target Neighborhood Hits	274	Shared Neighborhood Hits	76
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

STAC_MOUSE
θ value	1.81305 (rank : 756)	NC score	0.247408 (rank : 318)
Query Neighborhood Hits	1024	Target Neighborhood Hits	268	Shared Neighborhood Hits	154
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TM16H_MOUSE
θ value	1.81305 (rank : 757)	NC score	0.015654 (rank : 1467)
Query Neighborhood Hits	1024	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PB70, Q69ZE4	Gene names	Tmem16h, Kiaa1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TR19L_HUMAN
θ value	1.81305 (rank : 758)	NC score	0.014337 (rank : 1474)
Query Neighborhood Hits	1024	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

UBP8_HUMAN
θ value	1.81305 (rank : 759)	NC score	0.013868 (rank : 1480)
Query Neighborhood Hits	1024	Target Neighborhood Hits	751	Shared Neighborhood Hits	72
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

WBS14_MOUSE
θ value	1.81305 (rank : 760)	NC score	0.049015 (rank : 1292)
Query Neighborhood Hits	1024	Target Neighborhood Hits	171	Shared Neighborhood Hits	56
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ZIC5_HUMAN
θ value	1.81305 (rank : 761)	NC score	-0.007387 (rank : 1560)
Query Neighborhood Hits	1024	Target Neighborhood Hits	774	Shared Neighborhood Hits	60
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

ABCA7_HUMAN
θ value	2.36792 (rank : 762)	NC score	0.001957 (rank : 1543)
Query Neighborhood Hits	1024	Target Neighborhood Hits	144	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

AXN2_MOUSE
θ value	2.36792 (rank : 763)	NC score	0.015847 (rank : 1465)
Query Neighborhood Hits	1024	Target Neighborhood Hits	116	Shared Neighborhood Hits	26
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

BLNK_HUMAN
θ value	2.36792 (rank : 764)	NC score	0.070294 (rank : 888)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	67
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

C1QT2_HUMAN
θ value	2.36792 (rank : 765)	NC score	0.106806 (rank : 659)
Query Neighborhood Hits	1024	Target Neighborhood Hits	123	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXJ5	Gene names	C1QTNF2, CTRP2
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 2 precursor.

CITE4_HUMAN
θ value	2.36792 (rank : 766)	NC score	0.058464 (rank : 1055)
Query Neighborhood Hits	1024	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CO4A6_HUMAN
θ value	2.36792 (rank : 767)	NC score	0.174403 (rank : 443)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	116
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CT012_MOUSE
θ value	2.36792 (rank : 768)	NC score	0.261266 (rank : 292)
Query Neighborhood Hits	1024	Target Neighborhood Hits	229	Shared Neighborhood Hits	168
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

CTDP1_HUMAN
θ value	2.36792 (rank : 769)	NC score	0.124221 (rank : 580)
Query Neighborhood Hits	1024	Target Neighborhood Hits	416	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DCC_MOUSE
θ value	2.36792 (rank : 770)	NC score	0.042428 (rank : 1316)
Query Neighborhood Hits	1024	Target Neighborhood Hits	896	Shared Neighborhood Hits	198
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DEN1A_MOUSE
θ value	2.36792 (rank : 771)	NC score	0.042965 (rank : 1313)
Query Neighborhood Hits	1024	Target Neighborhood Hits	178	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

EPN1_MOUSE
θ value	2.36792 (rank : 772)	NC score	0.058029 (rank : 1064)
Query Neighborhood Hits	1024	Target Neighborhood Hits	240	Shared Neighborhood Hits	102
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

ES8L1_HUMAN
θ value	2.36792 (rank : 773)	NC score	0.139125 (rank : 526)
Query Neighborhood Hits	1024	Target Neighborhood Hits	162	Shared Neighborhood Hits	103
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

FOXE2_HUMAN
θ value	2.36792 (rank : 774)	NC score	0.041582 (rank : 1324)
Query Neighborhood Hits	1024	Target Neighborhood Hits	236	Shared Neighborhood Hits	98
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

FOXK1_MOUSE
θ value	2.36792 (rank : 775)	NC score	0.031357 (rank : 1374)
Query Neighborhood Hits	1024	Target Neighborhood Hits	215	Shared Neighborhood Hits	65
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

IRS2_HUMAN
θ value	2.36792 (rank : 776)	NC score	0.068557 (rank : 909)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

ITK_MOUSE
θ value	2.36792 (rank : 777)	NC score	0.087662 (rank : 757)
Query Neighborhood Hits	1024	Target Neighborhood Hits	985	Shared Neighborhood Hits	152
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

MEGF9_MOUSE
θ value	2.36792 (rank : 778)	NC score	0.074763 (rank : 846)
Query Neighborhood Hits	1024	Target Neighborhood Hits	896	Shared Neighborhood Hits	224
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MINT_MOUSE
θ value	2.36792 (rank : 779)	NC score	0.111467 (rank : 637)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1514	Shared Neighborhood Hits	311
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NEBU_HUMAN
θ value	2.36792 (rank : 780)	NC score	0.157418 (rank : 482)
Query Neighborhood Hits	1024	Target Neighborhood Hits	420	Shared Neighborhood Hits	154
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

OST6_HUMAN
θ value	2.36792 (rank : 781)	NC score	0.002541 (rank : 1539)
Query Neighborhood Hits	1024	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

PDE3A_MOUSE
θ value	2.36792 (rank : 782)	NC score	0.005998 (rank : 1528)
Query Neighborhood Hits	1024	Target Neighborhood Hits	115	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PRPC_HUMAN
θ value	2.36792 (rank : 783)	NC score	0.097573 (rank : 710)
Query Neighborhood Hits	1024	Target Neighborhood Hits	165	Shared Neighborhood Hits	74
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

RHG26_HUMAN
θ value	2.36792 (rank : 784)	NC score	0.126982 (rank : 576)
Query Neighborhood Hits	1024	Target Neighborhood Hits	281	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RUSC2_MOUSE
θ value	2.36792 (rank : 785)	NC score	0.103509 (rank : 673)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	148
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

S23IP_HUMAN
θ value	2.36792 (rank : 786)	NC score	0.049685 (rank : 1288)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

SHLB1_HUMAN
θ value	2.36792 (rank : 787)	NC score	0.107859 (rank : 653)
Query Neighborhood Hits	1024	Target Neighborhood Hits	96	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SNIP_MOUSE
θ value	2.36792 (rank : 788)	NC score	0.032211 (rank : 1370)
Query Neighborhood Hits	1024	Target Neighborhood Hits	319	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

STAC_HUMAN
θ value	2.36792 (rank : 789)	NC score	0.249186 (rank : 312)
Query Neighborhood Hits	1024	Target Neighborhood Hits	276	Shared Neighborhood Hits	158
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TAU_HUMAN
θ value	2.36792 (rank : 790)	NC score	0.128861 (rank : 566)
Query Neighborhood Hits	1024	Target Neighborhood Hits	448	Shared Neighborhood Hits	183
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

US6NL_HUMAN
θ value	2.36792 (rank : 791)	NC score	0.035752 (rank : 1353)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	67
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

VAV3_MOUSE
θ value	2.36792 (rank : 792)	NC score	0.182436 (rank : 427)
Query Neighborhood Hits	1024	Target Neighborhood Hits	404	Shared Neighborhood Hits	170
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ZN219_HUMAN
θ value	2.36792 (rank : 793)	NC score	0.001047 (rank : 1545)
Query Neighborhood Hits	1024	Target Neighborhood Hits	876	Shared Neighborhood Hits	111
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

ZN263_HUMAN
θ value	2.36792 (rank : 794)	NC score	-0.012297 (rank : 1566)
Query Neighborhood Hits	1024	Target Neighborhood Hits	795	Shared Neighborhood Hits	45
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).

ZN496_HUMAN
θ value	2.36792 (rank : 795)	NC score	-0.011691 (rank : 1565)
Query Neighborhood Hits	1024	Target Neighborhood Hits	743	Shared Neighborhood Hits	38
SwissProt Accessions	Q96IT1	Gene names	ZNF496
Domain Architecture	No domain graphic available
Description	Zinc finger protein 496.

3BP1_MOUSE
θ value	3.0926 (rank : 796)	NC score	0.058633 (rank : 1049)
Query Neighborhood Hits	1024	Target Neighborhood Hits	238	Shared Neighborhood Hits	73
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AAKG2_HUMAN
θ value	3.0926 (rank : 797)	NC score	0.019483 (rank : 1437)
Query Neighborhood Hits	1024	Target Neighborhood Hits	56	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UGJ0, Q53Y07, Q6NUI0, Q75MP4, Q9NUZ9, Q9UDN8, Q9ULX8	Gene names	PRKAG2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2) (H91620p).

AAKG2_MOUSE
θ value	3.0926 (rank : 798)	NC score	0.019095 (rank : 1439)
Query Neighborhood Hits	1024	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

AN13B_HUMAN
θ value	3.0926 (rank : 799)	NC score	0.326114 (rank : 234)
Query Neighborhood Hits	1024	Target Neighborhood Hits	265	Shared Neighborhood Hits	236
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	3.0926 (rank : 800)	NC score	0.326412 (rank : 232)
Query Neighborhood Hits	1024	Target Neighborhood Hits	276	Shared Neighborhood Hits	238
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANKY1_HUMAN
θ value	3.0926 (rank : 801)	NC score	0.317781 (rank : 241)
Query Neighborhood Hits	1024	Target Neighborhood Hits	248	Shared Neighborhood Hits	194
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANR37_HUMAN
θ value	3.0926 (rank : 802)	NC score	0.451225 (rank : 162)
Query Neighborhood Hits	1024	Target Neighborhood Hits	247	Shared Neighborhood Hits	232
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ASB6_HUMAN
θ value	3.0926 (rank : 803)	NC score	0.418698 (rank : 179)
Query Neighborhood Hits	1024	Target Neighborhood Hits	256	Shared Neighborhood Hits	223
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

BIN1_HUMAN
θ value	3.0926 (rank : 804)	NC score	0.107316 (rank : 658)
Query Neighborhood Hits	1024	Target Neighborhood Hits	335	Shared Neighborhood Hits	148
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

C1QRF_HUMAN
θ value	3.0926 (rank : 805)	NC score	0.091154 (rank : 738)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	66
SwissProt Accessions	O75973	Gene names	C1QL1, C1QRF, CRF
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

CBP_MOUSE
θ value	3.0926 (rank : 806)	NC score	0.141190 (rank : 518)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1051	Shared Neighborhood Hits	308
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CN155_HUMAN
θ value	3.0926 (rank : 807)	NC score	0.101636 (rank : 686)
Query Neighborhood Hits	1024	Target Neighborhood Hits	385	Shared Neighborhood Hits	110
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

COCA1_MOUSE
θ value	3.0926 (rank : 808)	NC score	0.075812 (rank : 839)
Query Neighborhood Hits	1024	Target Neighborhood Hits	467	Shared Neighborhood Hits	114
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COLQ_HUMAN
θ value	3.0926 (rank : 809)	NC score	0.139461 (rank : 523)
Query Neighborhood Hits	1024	Target Neighborhood Hits	193	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

CRKL_HUMAN
θ value	3.0926 (rank : 810)	NC score	0.217926 (rank : 356)
Query Neighborhood Hits	1024	Target Neighborhood Hits	313	Shared Neighborhood Hits	170
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	3.0926 (rank : 811)	NC score	0.210056 (rank : 369)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	160
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

DSCL1_HUMAN
θ value	3.0926 (rank : 812)	NC score	0.007500 (rank : 1516)
Query Neighborhood Hits	1024	Target Neighborhood Hits	589	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

ETV5_HUMAN
θ value	3.0926 (rank : 813)	NC score	0.020577 (rank : 1428)
Query Neighborhood Hits	1024	Target Neighborhood Hits	181	Shared Neighborhood Hits	61
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

EWS_HUMAN
θ value	3.0926 (rank : 814)	NC score	0.064979 (rank : 952)
Query Neighborhood Hits	1024	Target Neighborhood Hits	249	Shared Neighborhood Hits	76
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

EWS_MOUSE
θ value	3.0926 (rank : 815)	NC score	0.057810 (rank : 1068)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	76
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

GAK10_HUMAN
θ value	3.0926 (rank : 816)	NC score	0.067057 (rank : 929)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	132
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GP152_HUMAN
θ value	3.0926 (rank : 817)	NC score	0.041863 (rank : 1322)
Query Neighborhood Hits	1024	Target Neighborhood Hits	636	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

ICB1_MOUSE
θ value	3.0926 (rank : 818)	NC score	0.015515 (rank : 1468)
Query Neighborhood Hits	1024	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

LPP_HUMAN
θ value	3.0926 (rank : 819)	NC score	0.136786 (rank : 533)
Query Neighborhood Hits	1024	Target Neighborhood Hits	775	Shared Neighborhood Hits	293
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LRCH4_MOUSE
θ value	3.0926 (rank : 820)	NC score	0.006820 (rank : 1523)
Query Neighborhood Hits	1024	Target Neighborhood Hits	302	Shared Neighborhood Hits	29
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

MAGC1_HUMAN
θ value	3.0926 (rank : 821)	NC score	0.041924 (rank : 1320)
Query Neighborhood Hits	1024	Target Neighborhood Hits	431	Shared Neighborhood Hits	117
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MAGI2_HUMAN
θ value	3.0926 (rank : 822)	NC score	0.011915 (rank : 1494)
Query Neighborhood Hits	1024	Target Neighborhood Hits	373	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MPP4_HUMAN
θ value	3.0926 (rank : 823)	NC score	0.027436 (rank : 1396)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	51
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP8_HUMAN
θ value	3.0926 (rank : 824)	NC score	0.389340 (rank : 192)
Query Neighborhood Hits	1024	Target Neighborhood Hits	948	Shared Neighborhood Hits	286
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NFRKB_HUMAN
θ value	3.0926 (rank : 825)	NC score	0.052446 (rank : 1220)
Query Neighborhood Hits	1024	Target Neighborhood Hits	211	Shared Neighborhood Hits	60
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NRDC_HUMAN
θ value	3.0926 (rank : 826)	NC score	0.015045 (rank : 1470)
Query Neighborhood Hits	1024	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	O43847, O15241, O15242, Q5VUL0, Q96HB2, Q9NU57	Gene names	NRD1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

PRP4B_HUMAN
θ value	3.0926 (rank : 827)	NC score	0.036435 (rank : 1347)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1030	Shared Neighborhood Hits	105
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RAI1_MOUSE
θ value	3.0926 (rank : 828)	NC score	0.059719 (rank : 1028)
Query Neighborhood Hits	1024	Target Neighborhood Hits	344	Shared Neighborhood Hits	106
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RANB9_HUMAN
θ value	3.0926 (rank : 829)	NC score	0.041481 (rank : 1325)
Query Neighborhood Hits	1024	Target Neighborhood Hits	179	Shared Neighborhood Hits	69
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RD23B_MOUSE
θ value	3.0926 (rank : 830)	NC score	0.035364 (rank : 1355)
Query Neighborhood Hits	1024	Target Neighborhood Hits	189	Shared Neighborhood Hits	49
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RIN3_HUMAN
θ value	3.0926 (rank : 831)	NC score	0.041748 (rank : 1323)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RXRB_HUMAN
θ value	3.0926 (rank : 832)	NC score	0.010567 (rank : 1503)
Query Neighborhood Hits	1024	Target Neighborhood Hits	280	Shared Neighborhood Hits	69
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

SAPS1_HUMAN
θ value	3.0926 (rank : 833)	NC score	0.143532 (rank : 510)
Query Neighborhood Hits	1024	Target Neighborhood Hits	704	Shared Neighborhood Hits	284
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SMCA4_HUMAN
θ value	3.0926 (rank : 834)	NC score	0.037858 (rank : 1338)
Query Neighborhood Hits	1024	Target Neighborhood Hits	597	Shared Neighborhood Hits	145
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMOO_HUMAN
θ value	3.0926 (rank : 835)	NC score	0.069908 (rank : 896)
Query Neighborhood Hits	1024	Target Neighborhood Hits	391	Shared Neighborhood Hits	115
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SMRD3_MOUSE
θ value	3.0926 (rank : 836)	NC score	0.013128 (rank : 1485)
Query Neighborhood Hits	1024	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9Z1, Q921D3, Q9CX89, Q9DB99	Gene names	Smarcd3, Baf60c
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (mBAF60c).

ST5_HUMAN
θ value	3.0926 (rank : 837)	NC score	0.016570 (rank : 1456)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

TACC3_MOUSE
θ value	3.0926 (rank : 838)	NC score	0.023924 (rank : 1415)
Query Neighborhood Hits	1024	Target Neighborhood Hits	607	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TBC17_HUMAN
θ value	3.0926 (rank : 839)	NC score	0.016450 (rank : 1458)
Query Neighborhood Hits	1024	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HA65	Gene names	TBC1D17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

TOIP2_HUMAN
θ value	3.0926 (rank : 840)	NC score	0.010161 (rank : 1505)
Query Neighborhood Hits	1024	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

TTBK1_HUMAN
θ value	3.0926 (rank : 841)	NC score	0.056097 (rank : 1110)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1058	Shared Neighborhood Hits	165
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ULK2_HUMAN
θ value	3.0926 (rank : 842)	NC score	0.039021 (rank : 1329)
Query Neighborhood Hits	1024	Target Neighborhood Hits	979	Shared Neighborhood Hits	127
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

VTNC_MOUSE
θ value	3.0926 (rank : 843)	NC score	0.005067 (rank : 1529)
Query Neighborhood Hits	1024	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

YBOX2_MOUSE
θ value	3.0926 (rank : 844)	NC score	0.012239 (rank : 1490)
Query Neighborhood Hits	1024	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

ACK1_MOUSE
θ value	4.03905 (rank : 845)	NC score	0.081185 (rank : 795)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1080	Shared Neighborhood Hits	220
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ALG1_HUMAN
θ value	4.03905 (rank : 846)	NC score	0.011102 (rank : 1498)
Query Neighborhood Hits	1024	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BT22, Q6UVZ9, Q8N5Y4, Q9P2Y2	Gene names	ALG1, HMAT1, HMT1
Domain Architecture	No domain graphic available
Description	Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase) (GDP- Man:GlcNAc2-PP-dolichol mannosyltransferase) (Beta-1,4- mannosyltransferase) (Mannosyltransferase-1) (MT-1) (Hmat-1) (Asparagine-linked glycosylation protein 1 homolog).

AMPD3_MOUSE
θ value	4.03905 (rank : 847)	NC score	0.009938 (rank : 1506)
Query Neighborhood Hits	1024	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	O08739, O88692	Gene names	Ampd3
Domain Architecture
Description	AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (AMP deaminase H-type) (Heart-type AMPD).

ARMX2_HUMAN
θ value	4.03905 (rank : 848)	NC score	0.026449 (rank : 1402)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	40
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

ATX2_HUMAN
θ value	4.03905 (rank : 849)	NC score	0.064728 (rank : 955)
Query Neighborhood Hits	1024	Target Neighborhood Hits	375	Shared Neighborhood Hits	110
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

BAT3_MOUSE
θ value	4.03905 (rank : 850)	NC score	0.135309 (rank : 537)
Query Neighborhood Hits	1024	Target Neighborhood Hits	518	Shared Neighborhood Hits	214
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BIM_HUMAN
θ value	4.03905 (rank : 851)	NC score	0.100747 (rank : 693)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	84
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

BIM_MOUSE
θ value	4.03905 (rank : 852)	NC score	0.097707 (rank : 705)
Query Neighborhood Hits	1024	Target Neighborhood Hits	124	Shared Neighborhood Hits	78
SwissProt Accessions	O54918, O54919, O54920	Gene names	Bcl2l11, Bim
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

CBP_HUMAN
θ value	4.03905 (rank : 853)	NC score	0.115514 (rank : 615)
Query Neighborhood Hits	1024	Target Neighborhood Hits	941	Shared Neighborhood Hits	262
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CDC27_HUMAN
θ value	4.03905 (rank : 854)	NC score	0.014733 (rank : 1472)
Query Neighborhood Hits	1024	Target Neighborhood Hits	139	Shared Neighborhood Hits	13
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

CENG1_HUMAN
θ value	4.03905 (rank : 855)	NC score	0.229494 (rank : 343)
Query Neighborhood Hits	1024	Target Neighborhood Hits	544	Shared Neighborhood Hits	267
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CONA1_HUMAN
θ value	4.03905 (rank : 856)	NC score	0.163363 (rank : 470)
Query Neighborhood Hits	1024	Target Neighborhood Hits	281	Shared Neighborhood Hits	116
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CUTL2_MOUSE
θ value	4.03905 (rank : 857)	NC score	0.019881 (rank : 1435)
Query Neighborhood Hits	1024	Target Neighborhood Hits	771	Shared Neighborhood Hits	87
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DTX1_HUMAN
θ value	4.03905 (rank : 858)	NC score	0.017321 (rank : 1451)
Query Neighborhood Hits	1024	Target Neighborhood Hits	80	Shared Neighborhood Hits	30
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

FA8A1_HUMAN
θ value	4.03905 (rank : 859)	NC score	0.035352 (rank : 1356)
Query Neighborhood Hits	1024	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

MAGE1_HUMAN
θ value	4.03905 (rank : 860)	NC score	0.192551 (rank : 395)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1389	Shared Neighborhood Hits	421
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MINT_HUMAN
θ value	4.03905 (rank : 861)	NC score	0.073068 (rank : 866)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1291	Shared Neighborhood Hits	229
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MK07_HUMAN
θ value	4.03905 (rank : 862)	NC score	0.035974 (rank : 1350)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1087	Shared Neighborhood Hits	160
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MYCL1_HUMAN
θ value	4.03905 (rank : 863)	NC score	0.022515 (rank : 1418)
Query Neighborhood Hits	1024	Target Neighborhood Hits	146	Shared Neighborhood Hits	35
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NCOA6_HUMAN
θ value	4.03905 (rank : 864)	NC score	0.216862 (rank : 358)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1202	Shared Neighborhood Hits	412
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NFAC2_HUMAN
θ value	4.03905 (rank : 865)	NC score	0.020641 (rank : 1427)
Query Neighborhood Hits	1024	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

PER1_HUMAN
θ value	4.03905 (rank : 866)	NC score	0.040754 (rank : 1326)
Query Neighborhood Hits	1024	Target Neighborhood Hits	215	Shared Neighborhood Hits	70
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

SEM6C_MOUSE
θ value	4.03905 (rank : 867)	NC score	0.048431 (rank : 1296)
Query Neighborhood Hits	1024	Target Neighborhood Hits	352	Shared Neighborhood Hits	171
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

STS2_HUMAN
θ value	4.03905 (rank : 868)	NC score	0.086504 (rank : 761)
Query Neighborhood Hits	1024	Target Neighborhood Hits	108	Shared Neighborhood Hits	73
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

TAB3_MOUSE
θ value	4.03905 (rank : 869)	NC score	0.051007 (rank : 1255)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	93
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TIF1G_MOUSE
θ value	4.03905 (rank : 870)	NC score	0.023190 (rank : 1417)
Query Neighborhood Hits	1024	Target Neighborhood Hits	498	Shared Neighborhood Hits	84
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TMC8_MOUSE
θ value	4.03905 (rank : 871)	NC score	0.007118 (rank : 1521)
Query Neighborhood Hits	1024	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TN58, Q3TAL0, Q3UWI0, Q7TQ67	Gene names	Tmc8, Ever2
Domain Architecture	No domain graphic available
Description	Transmembrane channel-like protein 8 (Epidermodysplasia verruciformis protein 2 homolog).

TMPSD_MOUSE
θ value	4.03905 (rank : 872)	NC score	0.002045 (rank : 1541)
Query Neighborhood Hits	1024	Target Neighborhood Hits	334	Shared Neighborhood Hits	59
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TRPV3_HUMAN
θ value	4.03905 (rank : 873)	NC score	0.114625 (rank : 617)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

WASL_HUMAN
θ value	4.03905 (rank : 874)	NC score	0.122008 (rank : 586)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	135
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

3BP2_HUMAN
θ value	5.27518 (rank : 875)	NC score	0.060438 (rank : 1015)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	118
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ABL1_HUMAN
θ value	5.27518 (rank : 876)	NC score	0.096958 (rank : 712)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1220	Shared Neighborhood Hits	235
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	5.27518 (rank : 877)	NC score	0.097637 (rank : 708)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1178	Shared Neighborhood Hits	223
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ADA12_MOUSE
θ value	5.27518 (rank : 878)	NC score	0.027352 (rank : 1397)
Query Neighborhood Hits	1024	Target Neighborhood Hits	474	Shared Neighborhood Hits	140
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

APOA5_HUMAN
θ value	5.27518 (rank : 879)	NC score	0.007177 (rank : 1520)
Query Neighborhood Hits	1024	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Q788, Q6UWK9, Q9UBJ3	Gene names	APOA5, RAP3
Domain Architecture	No domain graphic available
Description	Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) (Regeneration-associated protein 3).

ATX1_MOUSE
θ value	5.27518 (rank : 880)	NC score	0.059309 (rank : 1035)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	98
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

AUTS2_HUMAN
θ value	5.27518 (rank : 881)	NC score	0.067386 (rank : 921)
Query Neighborhood Hits	1024	Target Neighborhood Hits	342	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

AXN2_HUMAN
θ value	5.27518 (rank : 882)	NC score	0.008213 (rank : 1513)
Query Neighborhood Hits	1024	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

BRD4_HUMAN
θ value	5.27518 (rank : 883)	NC score	0.070120 (rank : 892)
Query Neighborhood Hits	1024	Target Neighborhood Hits	851	Shared Neighborhood Hits	194
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CBL_HUMAN
θ value	5.27518 (rank : 884)	NC score	0.026660 (rank : 1400)
Query Neighborhood Hits	1024	Target Neighborhood Hits	353	Shared Neighborhood Hits	72
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CDN1C_HUMAN
θ value	5.27518 (rank : 885)	NC score	0.064947 (rank : 953)
Query Neighborhood Hits	1024	Target Neighborhood Hits	168	Shared Neighborhood Hits	63
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

DVL2_HUMAN
θ value	5.27518 (rank : 886)	NC score	0.013284 (rank : 1484)
Query Neighborhood Hits	1024	Target Neighborhood Hits	223	Shared Neighborhood Hits	35
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	5.27518 (rank : 887)	NC score	0.016340 (rank : 1460)
Query Neighborhood Hits	1024	Target Neighborhood Hits	233	Shared Neighborhood Hits	53
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

E2AK4_HUMAN
θ value	5.27518 (rank : 888)	NC score	0.028371 (rank : 1392)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1012	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

ECM1_MOUSE
θ value	5.27518 (rank : 889)	NC score	0.034705 (rank : 1361)
Query Neighborhood Hits	1024	Target Neighborhood Hits	105	Shared Neighborhood Hits	48
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

EMID2_MOUSE
θ value	5.27518 (rank : 890)	NC score	0.129301 (rank : 565)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	95
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EOMES_MOUSE
θ value	5.27518 (rank : 891)	NC score	0.004611 (rank : 1531)
Query Neighborhood Hits	1024	Target Neighborhood Hits	59	Shared Neighborhood Hits	10
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

FOXC2_HUMAN
θ value	5.27518 (rank : 892)	NC score	0.025959 (rank : 1407)
Query Neighborhood Hits	1024	Target Neighborhood Hits	236	Shared Neighborhood Hits	63
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

FOXD1_HUMAN
θ value	5.27518 (rank : 893)	NC score	0.013682 (rank : 1482)
Query Neighborhood Hits	1024	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q16676, Q12949	Gene names	FOXD1, FKHL8, FREAC4
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4).

FOXD2_MOUSE
θ value	5.27518 (rank : 894)	NC score	0.017254 (rank : 1452)
Query Neighborhood Hits	1024	Target Neighborhood Hits	130	Shared Neighborhood Hits	32
SwissProt Accessions	O35392	Gene names	Foxd2, Mf2
Domain Architecture
Description	Forkhead box protein D2 (Mesoderm/mesenchyme forkhead 2) (MF-2).

FOXJ3_MOUSE
θ value	5.27518 (rank : 895)	NC score	0.016127 (rank : 1462)
Query Neighborhood Hits	1024	Target Neighborhood Hits	190	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

FYB_MOUSE
θ value	5.27518 (rank : 896)	NC score	0.050865 (rank : 1261)
Query Neighborhood Hits	1024	Target Neighborhood Hits	194	Shared Neighborhood Hits	60
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GGA3_MOUSE
θ value	5.27518 (rank : 897)	NC score	0.032006 (rank : 1371)
Query Neighborhood Hits	1024	Target Neighborhood Hits	148	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GLI1_MOUSE
θ value	5.27518 (rank : 898)	NC score	-0.006280 (rank : 1554)
Query Neighborhood Hits	1024	Target Neighborhood Hits	785	Shared Neighborhood Hits	63
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

GSCR1_HUMAN
θ value	5.27518 (rank : 899)	NC score	0.139201 (rank : 525)
Query Neighborhood Hits	1024	Target Neighborhood Hits	674	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

INSM1_HUMAN
θ value	5.27518 (rank : 900)	NC score	-0.007430 (rank : 1561)
Query Neighborhood Hits	1024	Target Neighborhood Hits	683	Shared Neighborhood Hits	43
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

KLF17_HUMAN
θ value	5.27518 (rank : 901)	NC score	0.004718 (rank : 1530)
Query Neighborhood Hits	1024	Target Neighborhood Hits	882	Shared Neighborhood Hits	135
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

KRIT1_MOUSE
θ value	5.27518 (rank : 902)	NC score	0.418631 (rank : 180)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	219
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

LPP_MOUSE
θ value	5.27518 (rank : 903)	NC score	0.034630 (rank : 1362)
Query Neighborhood Hits	1024	Target Neighborhood Hits	247	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

M3K6_HUMAN
θ value	5.27518 (rank : 904)	NC score	0.031040 (rank : 1376)
Query Neighborhood Hits	1024	Target Neighborhood Hits	889	Shared Neighborhood Hits	91
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

MAP4_HUMAN
θ value	5.27518 (rank : 905)	NC score	0.066873 (rank : 934)
Query Neighborhood Hits	1024	Target Neighborhood Hits	428	Shared Neighborhood Hits	113
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MUC7_HUMAN
θ value	5.27518 (rank : 906)	NC score	0.126603 (rank : 578)
Query Neighborhood Hits	1024	Target Neighborhood Hits	538	Shared Neighborhood Hits	137
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NAB2_MOUSE
θ value	5.27518 (rank : 907)	NC score	0.014254 (rank : 1475)
Query Neighborhood Hits	1024	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q61127	Gene names	Nab2
Domain Architecture
Description	NGFI-A-binding protein 2 (EGR-1-binding protein 2).

PB1_HUMAN
θ value	5.27518 (rank : 908)	NC score	0.035611 (rank : 1354)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	62
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PCP2_MOUSE
θ value	5.27518 (rank : 909)	NC score	0.014025 (rank : 1479)
Query Neighborhood Hits	1024	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	P12660, P22941, Q3TV53	Gene names	Pcp2, Pcp-2
Domain Architecture
Description	Purkinje cell protein 2 (Protein PCD-5) (Purkinje cell-specific protein L7).

PCX3_MOUSE
θ value	5.27518 (rank : 910)	NC score	0.030230 (rank : 1382)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

PGBM_HUMAN
θ value	5.27518 (rank : 911)	NC score	0.009339 (rank : 1509)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1113	Shared Neighborhood Hits	68
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

RECQ5_HUMAN
θ value	5.27518 (rank : 912)	NC score	0.052374 (rank : 1222)
Query Neighborhood Hits	1024	Target Neighborhood Hits	390	Shared Neighborhood Hits	128
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RIMB1_MOUSE
θ value	5.27518 (rank : 913)	NC score	0.108778 (rank : 648)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1376	Shared Neighborhood Hits	274
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_MOUSE
θ value	5.27518 (rank : 914)	NC score	0.135021 (rank : 538)
Query Neighborhood Hits	1024	Target Neighborhood Hits	246	Shared Neighborhood Hits	104
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RPGF1_HUMAN
θ value	5.27518 (rank : 915)	NC score	0.031837 (rank : 1372)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	94
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SC24C_HUMAN
θ value	5.27518 (rank : 916)	NC score	0.175621 (rank : 439)
Query Neighborhood Hits	1024	Target Neighborhood Hits	662	Shared Neighborhood Hits	301
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TEX14_HUMAN
θ value	5.27518 (rank : 917)	NC score	0.288616 (rank : 271)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1103	Shared Neighborhood Hits	325
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

UBQL3_HUMAN
θ value	5.27518 (rank : 918)	NC score	0.021679 (rank : 1423)
Query Neighborhood Hits	1024	Target Neighborhood Hits	141	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

WASF3_HUMAN
θ value	5.27518 (rank : 919)	NC score	0.070515 (rank : 886)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WEE1_HUMAN
θ value	5.27518 (rank : 920)	NC score	0.031832 (rank : 1373)
Query Neighborhood Hits	1024	Target Neighborhood Hits	777	Shared Neighborhood Hits	77
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

ZN687_MOUSE
θ value	5.27518 (rank : 921)	NC score	0.007842 (rank : 1515)
Query Neighborhood Hits	1024	Target Neighborhood Hits	913	Shared Neighborhood Hits	117
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

5NT1B_HUMAN
θ value	6.88961 (rank : 922)	NC score	0.018649 (rank : 1441)
Query Neighborhood Hits	1024	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

A2AP_MOUSE
θ value	6.88961 (rank : 923)	NC score	-0.004420 (rank : 1551)
Query Neighborhood Hits	1024	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q61247	Gene names	Serpinf2, Pli
Domain Architecture
Description	Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP).

ANR22_HUMAN
θ value	6.88961 (rank : 924)	NC score	0.456873 (rank : 157)
Query Neighborhood Hits	1024	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANTR1_MOUSE
θ value	6.88961 (rank : 925)	NC score	0.036359 (rank : 1348)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ARHG4_MOUSE
θ value	6.88961 (rank : 926)	NC score	0.156462 (rank : 489)
Query Neighborhood Hits	1024	Target Neighborhood Hits	185	Shared Neighborhood Hits	104
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARI1B_HUMAN
θ value	6.88961 (rank : 927)	NC score	0.111784 (rank : 635)
Query Neighborhood Hits	1024	Target Neighborhood Hits	567	Shared Neighborhood Hits	208
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ASB14_HUMAN
θ value	6.88961 (rank : 928)	NC score	0.298240 (rank : 260)
Query Neighborhood Hits	1024	Target Neighborhood Hits	187	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

BORG1_HUMAN
θ value	6.88961 (rank : 929)	NC score	0.011779 (rank : 1495)
Query Neighborhood Hits	1024	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

C2TA_HUMAN
θ value	6.88961 (rank : 930)	NC score	0.028056 (rank : 1395)
Query Neighborhood Hits	1024	Target Neighborhood Hits	190	Shared Neighborhood Hits	65
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CD2L6_MOUSE
θ value	6.88961 (rank : 931)	NC score	0.023534 (rank : 1416)
Query Neighborhood Hits	1024	Target Neighborhood Hits	851	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

CK024_HUMAN
θ value	6.88961 (rank : 932)	NC score	0.142664 (rank : 512)
Query Neighborhood Hits	1024	Target Neighborhood Hits	408	Shared Neighborhood Hits	167
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CQ028_HUMAN
θ value	6.88961 (rank : 933)	NC score	0.012993 (rank : 1486)
Query Neighborhood Hits	1024	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

DEMA_MOUSE
θ value	6.88961 (rank : 934)	NC score	0.003082 (rank : 1537)
Query Neighborhood Hits	1024	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

DIAP1_HUMAN
θ value	6.88961 (rank : 935)	NC score	0.059720 (rank : 1027)
Query Neighborhood Hits	1024	Target Neighborhood Hits	784	Shared Neighborhood Hits	137
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

ELK1_HUMAN
θ value	6.88961 (rank : 936)	NC score	0.007182 (rank : 1519)
Query Neighborhood Hits	1024	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

FA61A_MOUSE
θ value	6.88961 (rank : 937)	NC score	0.020145 (rank : 1432)
Query Neighborhood Hits	1024	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

FOG1_MOUSE
θ value	6.88961 (rank : 938)	NC score	0.038521 (rank : 1331)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1237	Shared Neighborhood Hits	262
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOXC1_HUMAN
θ value	6.88961 (rank : 939)	NC score	0.024237 (rank : 1414)
Query Neighborhood Hits	1024	Target Neighborhood Hits	208	Shared Neighborhood Hits	63
SwissProt Accessions	Q12948, Q86UP7, Q9BYM1, Q9NUE5, Q9UDD0, Q9UP06	Gene names	FOXC1, FKHL7, FREAC3
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3).

FOXD2_HUMAN
θ value	6.88961 (rank : 940)	NC score	0.016890 (rank : 1455)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	38
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

MAST1_MOUSE
θ value	6.88961 (rank : 941)	NC score	0.025326 (rank : 1409)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1123	Shared Neighborhood Hits	137
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MIA2_MOUSE
θ value	6.88961 (rank : 942)	NC score	0.032850 (rank : 1368)
Query Neighborhood Hits	1024	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

MISS_MOUSE
θ value	6.88961 (rank : 943)	NC score	0.179445 (rank : 433)
Query Neighborhood Hits	1024	Target Neighborhood Hits	444	Shared Neighborhood Hits	220
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

NRG2_HUMAN
θ value	6.88961 (rank : 944)	NC score	0.019908 (rank : 1434)
Query Neighborhood Hits	1024	Target Neighborhood Hits	419	Shared Neighborhood Hits	43
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

OBSCN_HUMAN
θ value	6.88961 (rank : 945)	NC score	0.051619 (rank : 1241)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1931	Shared Neighborhood Hits	315
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OLFL3_HUMAN
θ value	6.88961 (rank : 946)	NC score	0.002006 (rank : 1542)
Query Neighborhood Hits	1024	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRN5, Q53FR1, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2	Gene names	OLFML3
Domain Architecture
Description	Olfactomedin-like protein 3 precursor (HNOEL-iso) (hOLF44).

PRELP_HUMAN
θ value	6.88961 (rank : 947)	NC score	-0.005453 (rank : 1553)
Query Neighborhood Hits	1024	Target Neighborhood Hits	295	Shared Neighborhood Hits	9
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

RAPH1_HUMAN
θ value	6.88961 (rank : 948)	NC score	0.114536 (rank : 618)
Query Neighborhood Hits	1024	Target Neighborhood Hits	593	Shared Neighborhood Hits	192
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RP3A_MOUSE
θ value	6.88961 (rank : 949)	NC score	0.074302 (rank : 852)
Query Neighborhood Hits	1024	Target Neighborhood Hits	510	Shared Neighborhood Hits	194
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RSMN_HUMAN
θ value	6.88961 (rank : 950)	NC score	0.050488 (rank : 1270)
Query Neighborhood Hits	1024	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
θ value	6.88961 (rank : 951)	NC score	0.050488 (rank : 1271)
Query Neighborhood Hits	1024	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

SF3A2_HUMAN
θ value	6.88961 (rank : 952)	NC score	0.105095 (rank : 669)
Query Neighborhood Hits	1024	Target Neighborhood Hits	263	Shared Neighborhood Hits	104
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SLIK3_MOUSE
θ value	6.88961 (rank : 953)	NC score	-0.006523 (rank : 1558)
Query Neighborhood Hits	1024	Target Neighborhood Hits	308	Shared Neighborhood Hits	15
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

SMAD6_MOUSE
θ value	6.88961 (rank : 954)	NC score	0.003369 (rank : 1536)
Query Neighborhood Hits	1024	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	O35182, Q9CW62	Gene names	Smad6, Madh6, Madh7, Msmad6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7).

SP7_MOUSE
θ value	6.88961 (rank : 955)	NC score	-0.006405 (rank : 1556)
Query Neighborhood Hits	1024	Target Neighborhood Hits	756	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

SSBP4_HUMAN
θ value	6.88961 (rank : 956)	NC score	0.215260 (rank : 359)
Query Neighborhood Hits	1024	Target Neighborhood Hits	753	Shared Neighborhood Hits	346
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

T22D4_HUMAN
θ value	6.88961 (rank : 957)	NC score	0.113544 (rank : 623)
Query Neighborhood Hits	1024	Target Neighborhood Hits	403	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

T240L_MOUSE
θ value	6.88961 (rank : 958)	NC score	0.015699 (rank : 1466)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	37
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

TBX19_HUMAN
θ value	6.88961 (rank : 959)	NC score	0.004369 (rank : 1533)
Query Neighborhood Hits	1024	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TJAP1_MOUSE
θ value	6.88961 (rank : 960)	NC score	0.014764 (rank : 1471)
Query Neighborhood Hits	1024	Target Neighborhood Hits	295	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TRHDE_HUMAN
θ value	6.88961 (rank : 961)	NC score	0.003912 (rank : 1535)
Query Neighborhood Hits	1024	Target Neighborhood Hits	49	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKU6, Q6UWJ4	Gene names	TRHDE
Domain Architecture
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

TSC2_MOUSE
θ value	6.88961 (rank : 962)	NC score	0.004294 (rank : 1534)
Query Neighborhood Hits	1024	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

VEGFB_MOUSE
θ value	6.88961 (rank : 963)	NC score	0.006965 (rank : 1522)
Query Neighborhood Hits	1024	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	P49766, Q3UG04, Q5D0B1, Q64290	Gene names	Vegfb, Vrf
Domain Architecture
Description	Vascular endothelial growth factor B precursor (VEGF-B) (VEGF-related factor) (VRF).

YETS2_HUMAN
θ value	6.88961 (rank : 964)	NC score	0.020960 (rank : 1425)
Query Neighborhood Hits	1024	Target Neighborhood Hits	212	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZN438_HUMAN
θ value	6.88961 (rank : 965)	NC score	0.007208 (rank : 1518)
Query Neighborhood Hits	1024	Target Neighborhood Hits	906	Shared Neighborhood Hits	114
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

4ET_MOUSE
θ value	8.99809 (rank : 966)	NC score	0.018580 (rank : 1444)
Query Neighborhood Hits	1024	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

ACK1_HUMAN
θ value	8.99809 (rank : 967)	NC score	0.080615 (rank : 799)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1140	Shared Neighborhood Hits	232
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ADA2A_MOUSE
θ value	8.99809 (rank : 968)	NC score	-0.016847 (rank : 1567)
Query Neighborhood Hits	1024	Target Neighborhood Hits	900	Shared Neighborhood Hits	30
SwissProt Accessions	Q01338	Gene names	Adra2a
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR).

AMOT_HUMAN
θ value	8.99809 (rank : 969)	NC score	0.037131 (rank : 1343)
Query Neighborhood Hits	1024	Target Neighborhood Hits	712	Shared Neighborhood Hits	117
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

ANTR1_HUMAN
θ value	8.99809 (rank : 970)	NC score	0.035224 (rank : 1357)
Query Neighborhood Hits	1024	Target Neighborhood Hits	128	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

APC_MOUSE
θ value	8.99809 (rank : 971)	NC score	0.030424 (rank : 1380)
Query Neighborhood Hits	1024	Target Neighborhood Hits	441	Shared Neighborhood Hits	52
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ARHGF_HUMAN
θ value	8.99809 (rank : 972)	NC score	0.071994 (rank : 873)
Query Neighborhood Hits	1024	Target Neighborhood Hits	214	Shared Neighborhood Hits	78
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARI3A_HUMAN
θ value	8.99809 (rank : 973)	NC score	0.017390 (rank : 1450)
Query Neighborhood Hits	1024	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

ASB12_HUMAN
θ value	8.99809 (rank : 974)	NC score	0.450494 (rank : 163)
Query Neighborhood Hits	1024	Target Neighborhood Hits	263	Shared Neighborhood Hits	243
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB4_MOUSE
θ value	8.99809 (rank : 975)	NC score	0.457703 (rank : 155)
Query Neighborhood Hits	1024	Target Neighborhood Hits	265	Shared Neighborhood Hits	245
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ATX2_MOUSE
θ value	8.99809 (rank : 976)	NC score	0.077860 (rank : 822)
Query Neighborhood Hits	1024	Target Neighborhood Hits	445	Shared Neighborhood Hits	146
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BCAR3_HUMAN
θ value	8.99809 (rank : 977)	NC score	0.034253 (rank : 1363)
Query Neighborhood Hits	1024	Target Neighborhood Hits	129	Shared Neighborhood Hits	35
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

CD2_HUMAN
θ value	8.99809 (rank : 978)	NC score	0.127389 (rank : 574)
Query Neighborhood Hits	1024	Target Neighborhood Hits	504	Shared Neighborhood Hits	200
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CS021_HUMAN
θ value	8.99809 (rank : 979)	NC score	0.018334 (rank : 1445)
Query Neighborhood Hits	1024	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

DEN1A_HUMAN
θ value	8.99809 (rank : 980)	NC score	0.028587 (rank : 1391)
Query Neighborhood Hits	1024	Target Neighborhood Hits	176	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DIAP2_HUMAN
θ value	8.99809 (rank : 981)	NC score	0.030507 (rank : 1379)
Query Neighborhood Hits	1024	Target Neighborhood Hits	342	Shared Neighborhood Hits	75
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DLG5_HUMAN
θ value	8.99809 (rank : 982)	NC score	0.034757 (rank : 1360)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1088	Shared Neighborhood Hits	166
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DMWD_MOUSE
θ value	8.99809 (rank : 983)	NC score	0.011629 (rank : 1496)
Query Neighborhood Hits	1024	Target Neighborhood Hits	282	Shared Neighborhood Hits	37
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

DOC2B_MOUSE
θ value	8.99809 (rank : 984)	NC score	0.020642 (rank : 1426)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

ENAH_HUMAN
θ value	8.99809 (rank : 985)	NC score	0.073910 (rank : 856)
Query Neighborhood Hits	1024	Target Neighborhood Hits	784	Shared Neighborhood Hits	131
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

FGD1_MOUSE
θ value	8.99809 (rank : 986)	NC score	0.077872 (rank : 821)
Query Neighborhood Hits	1024	Target Neighborhood Hits	387	Shared Neighborhood Hits	154
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FMN1A_MOUSE
θ value	8.99809 (rank : 987)	NC score	0.064338 (rank : 959)
Query Neighborhood Hits	1024	Target Neighborhood Hits	423	Shared Neighborhood Hits	135
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	8.99809 (rank : 988)	NC score	0.064154 (rank : 963)
Query Neighborhood Hits	1024	Target Neighborhood Hits	447	Shared Neighborhood Hits	129
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FOXJ3_HUMAN
θ value	8.99809 (rank : 989)	NC score	0.016311 (rank : 1461)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

FUBP2_HUMAN
θ value	8.99809 (rank : 990)	NC score	0.030122 (rank : 1384)
Query Neighborhood Hits	1024	Target Neighborhood Hits	145	Shared Neighborhood Hits	59
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

GLIS3_HUMAN
θ value	8.99809 (rank : 991)	NC score	-0.008995 (rank : 1563)
Query Neighborhood Hits	1024	Target Neighborhood Hits	758	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

IER5_HUMAN
θ value	8.99809 (rank : 992)	NC score	0.030399 (rank : 1381)
Query Neighborhood Hits	1024	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VY09, Q8WY68, Q9NY49, Q9NZP9	Gene names	IER5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

JIP3_HUMAN
θ value	8.99809 (rank : 993)	NC score	0.060918 (rank : 1009)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1039	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

K0460_HUMAN
θ value	8.99809 (rank : 994)	NC score	0.039817 (rank : 1328)
Query Neighborhood Hits	1024	Target Neighborhood Hits	357	Shared Neighborhood Hits	85
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K0460_MOUSE
θ value	8.99809 (rank : 995)	NC score	0.043898 (rank : 1309)
Query Neighborhood Hits	1024	Target Neighborhood Hits	374	Shared Neighborhood Hits	92
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

KRIT1_HUMAN
θ value	8.99809 (rank : 996)	NC score	0.405493 (rank : 183)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	214
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

M3K14_HUMAN
θ value	8.99809 (rank : 997)	NC score	0.029468 (rank : 1387)
Query Neighborhood Hits	1024	Target Neighborhood Hits	887	Shared Neighborhood Hits	104
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

MAGI2_MOUSE
θ value	8.99809 (rank : 998)	NC score	0.014237 (rank : 1476)
Query Neighborhood Hits	1024	Target Neighborhood Hits	370	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MATK_MOUSE
θ value	8.99809 (rank : 999)	NC score	0.074109 (rank : 854)
Query Neighborhood Hits	1024	Target Neighborhood Hits	952	Shared Neighborhood Hits	117
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

NANO3_HUMAN
θ value	8.99809 (rank : 1000)	NC score	0.006472 (rank : 1526)
Query Neighborhood Hits	1024	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P60323	Gene names	NANOS3, NOS3
Domain Architecture	No domain graphic available
Description	Nanos homolog 3.

NIPBL_HUMAN
θ value	8.99809 (rank : 1001)	NC score	0.073090 (rank : 864)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1311	Shared Neighborhood Hits	187
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	8.99809 (rank : 1002)	NC score	0.065869 (rank : 943)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1041	Shared Neighborhood Hits	167
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PLCG1_HUMAN
θ value	8.99809 (rank : 1003)	NC score	0.154850 (rank : 490)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	141
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	8.99809 (rank : 1004)	NC score	0.160668 (rank : 474)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	149
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLS3_HUMAN
θ value	8.99809 (rank : 1005)	NC score	0.011479 (rank : 1497)
Query Neighborhood Hits	1024	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRY6, Q8NBW6, Q96F13	Gene names	PLSCR3
Domain Architecture
Description	Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3).

R3HD1_HUMAN
θ value	8.99809 (rank : 1006)	NC score	0.036471 (rank : 1346)
Query Neighborhood Hits	1024	Target Neighborhood Hits	203	Shared Neighborhood Hits	65
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

R3HD2_MOUSE
θ value	8.99809 (rank : 1007)	NC score	0.082574 (rank : 788)
Query Neighborhood Hits	1024	Target Neighborhood Hits	397	Shared Neighborhood Hits	151
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RC3H1_HUMAN
θ value	8.99809 (rank : 1008)	NC score	0.045835 (rank : 1304)
Query Neighborhood Hits	1024	Target Neighborhood Hits	433	Shared Neighborhood Hits	114
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RECQ4_MOUSE
θ value	8.99809 (rank : 1009)	NC score	0.004567 (rank : 1532)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	33
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RP1L1_MOUSE
θ value	8.99809 (rank : 1010)	NC score	0.030106 (rank : 1385)
Query Neighborhood Hits	1024	Target Neighborhood Hits	170	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

S3TC2_MOUSE
θ value	8.99809 (rank : 1011)	NC score	0.038217 (rank : 1334)
Query Neighborhood Hits	1024	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

SIGL5_HUMAN
θ value	8.99809 (rank : 1012)	NC score	-0.000425 (rank : 1546)
Query Neighborhood Hits	1024	Target Neighborhood Hits	246	Shared Neighborhood Hits	14
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

SLAP2_HUMAN
θ value	8.99809 (rank : 1013)	NC score	0.150352 (rank : 498)
Query Neighborhood Hits	1024	Target Neighborhood Hits	139	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SOX17_HUMAN
θ value	8.99809 (rank : 1014)	NC score	0.011018 (rank : 1499)
Query Neighborhood Hits	1024	Target Neighborhood Hits	108	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SP7_HUMAN
θ value	8.99809 (rank : 1015)	NC score	-0.008733 (rank : 1562)
Query Neighborhood Hits	1024	Target Neighborhood Hits	734	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

STAT6_HUMAN
θ value	8.99809 (rank : 1016)	NC score	0.016506 (rank : 1457)
Query Neighborhood Hits	1024	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

SYN2_HUMAN
θ value	8.99809 (rank : 1017)	NC score	0.042602 (rank : 1314)
Query Neighborhood Hits	1024	Target Neighborhood Hits	213	Shared Neighborhood Hits	73
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TITIN_HUMAN
θ value	8.99809 (rank : 1018)	NC score	0.035214 (rank : 1358)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2923	Shared Neighborhood Hits	291
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

UB7I1_HUMAN
θ value	8.99809 (rank : 1019)	NC score	0.020490 (rank : 1431)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

ULK2_MOUSE
θ value	8.99809 (rank : 1020)	NC score	0.037249 (rank : 1342)
Query Neighborhood Hits	1024	Target Neighborhood Hits	943	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

UN119_HUMAN
θ value	8.99809 (rank : 1021)	NC score	0.009503 (rank : 1508)
Query Neighborhood Hits	1024	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q13432, O95126	Gene names	UNC119, RG4
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (HRG4).

VINEX_MOUSE
θ value	8.99809 (rank : 1022)	NC score	0.247606 (rank : 315)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	181
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

WNK4_HUMAN
θ value	8.99809 (rank : 1023)	NC score	0.044661 (rank : 1306)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1043	Shared Neighborhood Hits	159
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZDH18_HUMAN
θ value	8.99809 (rank : 1024)	NC score	0.026686 (rank : 1399)
Query Neighborhood Hits	1024	Target Neighborhood Hits	72	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NUE0, Q5JYH0, Q9H020	Gene names	ZDHHC18
Domain Architecture
Description	Palmitoyltransferase ZDHHC18 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 18) (DHHC-18).

AATK_MOUSE
θ value	θ > 10 (rank : 1025)	NC score	0.067352 (rank : 922)
Query Neighborhood Hits	1024	Target Neighborhood Hits	942	Shared Neighborhood Hits	142
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABI3_HUMAN
θ value	θ > 10 (rank : 1026)	NC score	0.192504 (rank : 396)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	162
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABL2_HUMAN
θ value	θ > 10 (rank : 1027)	NC score	0.087740 (rank : 756)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1045	Shared Neighborhood Hits	166
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABTB1_HUMAN
θ value	θ > 10 (rank : 1028)	NC score	0.156731 (rank : 487)
Query Neighborhood Hits	1024	Target Neighborhood Hits	325	Shared Neighborhood Hits	156
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	θ > 10 (rank : 1029)	NC score	0.184392 (rank : 419)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	171
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ADIPO_HUMAN
θ value	θ > 10 (rank : 1030)	NC score	0.113726 (rank : 622)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	70
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

ADIPO_MOUSE
θ value	θ > 10 (rank : 1031)	NC score	0.113486 (rank : 624)
Query Neighborhood Hits	1024	Target Neighborhood Hits	182	Shared Neighborhood Hits	78
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

AFF1_HUMAN
θ value	θ > 10 (rank : 1032)	NC score	0.057520 (rank : 1074)
Query Neighborhood Hits	1024	Target Neighborhood Hits	506	Shared Neighborhood Hits	111
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AKAP2_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.077032 (rank : 830)
Query Neighborhood Hits	1024	Target Neighborhood Hits	507	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ALEX_MOUSE
θ value	θ > 10 (rank : 1034)	NC score	0.055973 (rank : 1114)
Query Neighborhood Hits	1024	Target Neighborhood Hits	197	Shared Neighborhood Hits	77
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALK_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.057370 (rank : 1080)
Query Neighborhood Hits	1024	Target Neighborhood Hits	795	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 1036)	NC score	0.058553 (rank : 1051)
Query Neighborhood Hits	1024	Target Neighborhood Hits	811	Shared Neighborhood Hits	86
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

AMPH_HUMAN
θ value	θ > 10 (rank : 1037)	NC score	0.114310 (rank : 620)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	159
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 1038)	NC score	0.091858 (rank : 736)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	105
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANKR9_HUMAN
θ value	θ > 10 (rank : 1039)	NC score	0.123292 (rank : 583)
Query Neighborhood Hits	1024	Target Neighborhood Hits	99	Shared Neighborhood Hits	90
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	θ > 10 (rank : 1040)	NC score	0.154555 (rank : 491)
Query Neighborhood Hits	1024	Target Neighborhood Hits	120	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKZ1_HUMAN
θ value	θ > 10 (rank : 1041)	NC score	0.177470 (rank : 435)
Query Neighborhood Hits	1024	Target Neighborhood Hits	236	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANKZ1_MOUSE
θ value	θ > 10 (rank : 1042)	NC score	0.183525 (rank : 424)
Query Neighborhood Hits	1024	Target Neighborhood Hits	208	Shared Neighborhood Hits	146
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ANPRA_MOUSE
θ value	θ > 10 (rank : 1043)	NC score	0.050546 (rank : 1269)
Query Neighborhood Hits	1024	Target Neighborhood Hits	600	Shared Neighborhood Hits	60
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRB_HUMAN
θ value	θ > 10 (rank : 1044)	NC score	0.050006 (rank : 1287)
Query Neighborhood Hits	1024	Target Neighborhood Hits	646	Shared Neighborhood Hits	64
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	θ > 10 (rank : 1045)	NC score	0.050918 (rank : 1260)
Query Neighborhood Hits	1024	Target Neighborhood Hits	607	Shared Neighborhood Hits	62
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANR33_HUMAN
θ value	θ > 10 (rank : 1046)	NC score	0.364413 (rank : 208)
Query Neighborhood Hits	1024	Target Neighborhood Hits	215	Shared Neighborhood Hits	205
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR33_MOUSE
θ value	θ > 10 (rank : 1047)	NC score	0.370372 (rank : 202)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	215
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR40_HUMAN
θ value	θ > 10 (rank : 1048)	NC score	0.353174 (rank : 218)
Query Neighborhood Hits	1024	Target Neighborhood Hits	224	Shared Neighborhood Hits	200
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	θ > 10 (rank : 1049)	NC score	0.352847 (rank : 219)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	202
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR41_HUMAN
θ value	θ > 10 (rank : 1050)	NC score	0.455208 (rank : 158)
Query Neighborhood Hits	1024	Target Neighborhood Hits	332	Shared Neighborhood Hits	277
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR43_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.348265 (rank : 224)
Query Neighborhood Hits	1024	Target Neighborhood Hits	209	Shared Neighborhood Hits	195
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_MOUSE
θ value	θ > 10 (rank : 1052)	NC score	0.349934 (rank : 223)
Query Neighborhood Hits	1024	Target Neighborhood Hits	214	Shared Neighborhood Hits	198
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

APS_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.061547 (rank : 996)
Query Neighborhood Hits	1024	Target Neighborhood Hits	162	Shared Neighborhood Hits	61
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APXL_HUMAN
θ value	θ > 10 (rank : 1054)	NC score	0.055450 (rank : 1131)
Query Neighborhood Hits	1024	Target Neighborhood Hits	553	Shared Neighborhood Hits	131
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ARAF_HUMAN
θ value	θ > 10 (rank : 1055)	NC score	0.053953 (rank : 1181)
Query Neighborhood Hits	1024	Target Neighborhood Hits	924	Shared Neighborhood Hits	102
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.052419 (rank : 1221)
Query Neighborhood Hits	1024	Target Neighborhood Hits	874	Shared Neighborhood Hits	84
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

ARHG1_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.061957 (rank : 989)
Query Neighborhood Hits	1024	Target Neighborhood Hits	176	Shared Neighborhood Hits	73
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 1058)	NC score	0.075896 (rank : 838)
Query Neighborhood Hits	1024	Target Neighborhood Hits	266	Shared Neighborhood Hits	114
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG3_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.065550 (rank : 949)
Query Neighborhood Hits	1024	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 1060)	NC score	0.064752 (rank : 954)
Query Neighborhood Hits	1024	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG5_HUMAN
θ value	θ > 10 (rank : 1061)	NC score	0.077271 (rank : 828)
Query Neighborhood Hits	1024	Target Neighborhood Hits	172	Shared Neighborhood Hits	81
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG8_HUMAN
θ value	θ > 10 (rank : 1062)	NC score	0.060545 (rank : 1014)
Query Neighborhood Hits	1024	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 1063)	NC score	0.064102 (rank : 964)
Query Neighborhood Hits	1024	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGA_HUMAN
θ value	θ > 10 (rank : 1064)	NC score	0.055982 (rank : 1112)
Query Neighborhood Hits	1024	Target Neighborhood Hits	187	Shared Neighborhood Hits	36
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 1065)	NC score	0.059232 (rank : 1036)
Query Neighborhood Hits	1024	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 1066)	NC score	0.051183 (rank : 1250)
Query Neighborhood Hits	1024	Target Neighborhood Hits	375	Shared Neighborhood Hits	65
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 1067)	NC score	0.060934 (rank : 1008)
Query Neighborhood Hits	1024	Target Neighborhood Hits	129	Shared Neighborhood Hits	48
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	θ > 10 (rank : 1068)	NC score	0.069474 (rank : 901)
Query Neighborhood Hits	1024	Target Neighborhood Hits	152	Shared Neighborhood Hits	63
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARMX2_MOUSE
θ value	θ > 10 (rank : 1069)	NC score	0.070898 (rank : 883)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	166
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ASB12_MOUSE
θ value	θ > 10 (rank : 1070)	NC score	0.450429 (rank : 164)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	242
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB6_MOUSE
θ value	θ > 10 (rank : 1071)	NC score	0.412870 (rank : 181)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	224
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ATX2L_HUMAN
θ value	θ > 10 (rank : 1072)	NC score	0.072163 (rank : 871)
Query Neighborhood Hits	1024	Target Neighborhood Hits	443	Shared Neighborhood Hits	147
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2L_MOUSE
θ value	θ > 10 (rank : 1073)	NC score	0.069667 (rank : 898)
Query Neighborhood Hits	1024	Target Neighborhood Hits	401	Shared Neighborhood Hits	142
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

ATX7_HUMAN
θ value	θ > 10 (rank : 1074)	NC score	0.062878 (rank : 979)
Query Neighborhood Hits	1024	Target Neighborhood Hits	351	Shared Neighborhood Hits	129
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

ATX7_MOUSE
θ value	θ > 10 (rank : 1075)	NC score	0.074824 (rank : 844)
Query Neighborhood Hits	1024	Target Neighborhood Hits	328	Shared Neighborhood Hits	151
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BAG3_HUMAN
θ value	θ > 10 (rank : 1076)	NC score	0.068084 (rank : 915)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	129
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAG3_MOUSE
θ value	θ > 10 (rank : 1077)	NC score	0.118834 (rank : 599)
Query Neighborhood Hits	1024	Target Neighborhood Hits	513	Shared Neighborhood Hits	217
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.062747 (rank : 983)
Query Neighborhood Hits	1024	Target Neighborhood Hits	321	Shared Neighborhood Hits	64
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT3_HUMAN
θ value	θ > 10 (rank : 1079)	NC score	0.127989 (rank : 572)
Query Neighborhood Hits	1024	Target Neighborhood Hits	490	Shared Neighborhood Hits	219
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.060779 (rank : 1012)
Query Neighborhood Hits	1024	Target Neighborhood Hits	780	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BCL7C_MOUSE
θ value	θ > 10 (rank : 1081)	NC score	0.060823 (rank : 1010)
Query Neighborhood Hits	1024	Target Neighborhood Hits	170	Shared Neighborhood Hits	97
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

BCR_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.056973 (rank : 1091)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	51
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

BI2L1_HUMAN
θ value	θ > 10 (rank : 1083)	NC score	0.055119 (rank : 1144)
Query Neighborhood Hits	1024	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BMX_HUMAN
θ value	θ > 10 (rank : 1084)	NC score	0.070697 (rank : 885)
Query Neighborhood Hits	1024	Target Neighborhood Hits	942	Shared Neighborhood Hits	102
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 1085)	NC score	0.070388 (rank : 887)
Query Neighborhood Hits	1024	Target Neighborhood Hits	912	Shared Neighborhood Hits	97
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BRAF1_HUMAN
θ value	θ > 10 (rank : 1086)	NC score	0.053130 (rank : 1202)
Query Neighborhood Hits	1024	Target Neighborhood Hits	883	Shared Neighborhood Hits	88
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BRD4_MOUSE
θ value	θ > 10 (rank : 1087)	NC score	0.077134 (rank : 829)
Query Neighborhood Hits	1024	Target Neighborhood Hits	845	Shared Neighborhood Hits	185
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

C1QA_HUMAN
θ value	θ > 10 (rank : 1088)	NC score	0.120447 (rank : 591)
Query Neighborhood Hits	1024	Target Neighborhood Hits	179	Shared Neighborhood Hits	83
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

C1QA_MOUSE
θ value	θ > 10 (rank : 1089)	NC score	0.096678 (rank : 713)
Query Neighborhood Hits	1024	Target Neighborhood Hits	116	Shared Neighborhood Hits	54
SwissProt Accessions	P98086	Gene names	C1qa
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

C1QB_HUMAN
θ value	θ > 10 (rank : 1090)	NC score	0.099407 (rank : 699)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	58
SwissProt Accessions	P02746, Q5T959, Q96H17	Gene names	C1QB
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

C1QB_MOUSE
θ value	θ > 10 (rank : 1091)	NC score	0.102428 (rank : 683)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	62
SwissProt Accessions	P14106	Gene names	C1qb
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

C1QC_HUMAN
θ value	θ > 10 (rank : 1092)	NC score	0.101511 (rank : 687)
Query Neighborhood Hits	1024	Target Neighborhood Hits	124	Shared Neighborhood Hits	59
SwissProt Accessions	P02747, Q7Z502, Q96DL2, Q96H05	Gene names	C1QC, C1QG
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

C1QC_MOUSE
θ value	θ > 10 (rank : 1093)	NC score	0.112366 (rank : 629)
Query Neighborhood Hits	1024	Target Neighborhood Hits	150	Shared Neighborhood Hits	68
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

C1QL3_MOUSE
θ value	θ > 10 (rank : 1094)	NC score	0.086828 (rank : 759)
Query Neighborhood Hits	1024	Target Neighborhood Hits	127	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ESN4	Gene names	C1ql3, C1ql
Domain Architecture
Description	Complement C1q-like protein 3 precursor (Gliacolin).

C1QRF_MOUSE
θ value	θ > 10 (rank : 1095)	NC score	0.087460 (rank : 758)
Query Neighborhood Hits	1024	Target Neighborhood Hits	140	Shared Neighborhood Hits	63
SwissProt Accessions	O88992	Gene names	C1ql1, C1qrf, Crf
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

C1QT1_HUMAN
θ value	θ > 10 (rank : 1096)	NC score	0.090762 (rank : 739)
Query Neighborhood Hits	1024	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BXJ1, Q96NF2, Q9GZR4	Gene names	C1QTNF1, CTRP1
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 1 precursor (G protein-coupled receptor-interacting protein) (GIP).

C1QT3_HUMAN
θ value	θ > 10 (rank : 1097)	NC score	0.083068 (rank : 786)
Query Neighborhood Hits	1024	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXJ4, Q6MZN1, Q96KY1	Gene names	C1QTNF3, CTRP3
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 3 precursor (Secretory protein CORS26).

C1QT3_MOUSE
θ value	θ > 10 (rank : 1098)	NC score	0.084109 (rank : 779)
Query Neighborhood Hits	1024	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ES30	Gene names	C1qtnf3, Cors26, Ctrp3
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 3 precursor (Secretory protein CORS26).

C1QT5_HUMAN
θ value	θ > 10 (rank : 1099)	NC score	0.097316 (rank : 711)
Query Neighborhood Hits	1024	Target Neighborhood Hits	137	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BXJ0, Q8N6P2, Q9UFX4	Gene names	C1QTNF5, CTRP5
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

C1QT5_MOUSE
θ value	θ > 10 (rank : 1100)	NC score	0.094711 (rank : 722)
Query Neighborhood Hits	1024	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

C1QT6_HUMAN
θ value	θ > 10 (rank : 1101)	NC score	0.080330 (rank : 804)
Query Neighborhood Hits	1024	Target Neighborhood Hits	122	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXI9	Gene names	C1QTNF6, CTRP6
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 6 precursor.

C1QT7_HUMAN
θ value	θ > 10 (rank : 1102)	NC score	0.098147 (rank : 703)
Query Neighborhood Hits	1024	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXJ2	Gene names	C1QTNF7, CTRP7
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

C1QT7_MOUSE
θ value	θ > 10 (rank : 1103)	NC score	0.100534 (rank : 696)
Query Neighborhood Hits	1024	Target Neighborhood Hits	124	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BVD7, Q8CHX9	Gene names	C1qtnf7, Ctrp7
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

C1QT8_HUMAN
θ value	θ > 10 (rank : 1104)	NC score	0.071669 (rank : 876)
Query Neighborhood Hits	1024	Target Neighborhood Hits	94	Shared Neighborhood Hits	47
SwissProt Accessions	P60827	Gene names	C1QTNF8
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 8 precursor.

CABIN_HUMAN
θ value	θ > 10 (rank : 1105)	NC score	0.091205 (rank : 737)
Query Neighborhood Hits	1024	Target Neighborhood Hits	490	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CAC1G_HUMAN
θ value	θ > 10 (rank : 1106)	NC score	0.050299 (rank : 1277)
Query Neighborhood Hits	1024	Target Neighborhood Hits	587	Shared Neighborhood Hits	216
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CBX2_HUMAN
θ value	θ > 10 (rank : 1107)	NC score	0.061202 (rank : 1005)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	118
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CCNK_MOUSE
θ value	θ > 10 (rank : 1108)	NC score	0.068422 (rank : 911)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	112
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD248_HUMAN
θ value	θ > 10 (rank : 1109)	NC score	0.065839 (rank : 944)
Query Neighborhood Hits	1024	Target Neighborhood Hits	679	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 1110)	NC score	0.050162 (rank : 1280)
Query Neighborhood Hits	1024	Target Neighborhood Hits	578	Shared Neighborhood Hits	153
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD2A1_HUMAN
θ value	θ > 10 (rank : 1111)	NC score	0.354686 (rank : 217)
Query Neighborhood Hits	1024	Target Neighborhood Hits	196	Shared Neighborhood Hits	182
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CD2A1_MOUSE
θ value	θ > 10 (rank : 1112)	NC score	0.403256 (rank : 184)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	191
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CDN2B_HUMAN
θ value	θ > 10 (rank : 1113)	NC score	0.346508 (rank : 225)
Query Neighborhood Hits	1024	Target Neighborhood Hits	196	Shared Neighborhood Hits	181
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CDN2B_MOUSE
θ value	θ > 10 (rank : 1114)	NC score	0.371066 (rank : 200)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	186
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CECR2_HUMAN
θ value	θ > 10 (rank : 1115)	NC score	0.130176 (rank : 561)
Query Neighborhood Hits	1024	Target Neighborhood Hits	543	Shared Neighborhood Hits	245
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CENA1_HUMAN
θ value	θ > 10 (rank : 1116)	NC score	0.050935 (rank : 1258)
Query Neighborhood Hits	1024	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CEND1_HUMAN
θ value	θ > 10 (rank : 1117)	NC score	0.055907 (rank : 1116)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND1_MOUSE
θ value	θ > 10 (rank : 1118)	NC score	0.055606 (rank : 1127)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND2_HUMAN
θ value	θ > 10 (rank : 1119)	NC score	0.054528 (rank : 1160)
Query Neighborhood Hits	1024	Target Neighborhood Hits	166	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_MOUSE
θ value	θ > 10 (rank : 1120)	NC score	0.058094 (rank : 1061)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CGRE1_HUMAN
θ value	θ > 10 (rank : 1121)	NC score	0.111346 (rank : 640)
Query Neighborhood Hits	1024	Target Neighborhood Hits	354	Shared Neighborhood Hits	122
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CI079_HUMAN
θ value	θ > 10 (rank : 1122)	NC score	0.053339 (rank : 1193)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	94
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CIP4_HUMAN
θ value	θ > 10 (rank : 1123)	NC score	0.092054 (rank : 735)
Query Neighborhood Hits	1024	Target Neighborhood Hits	374	Shared Neighborhood Hits	78
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CJ047_HUMAN
θ value	θ > 10 (rank : 1124)	NC score	0.067287 (rank : 925)
Query Neighborhood Hits	1024	Target Neighborhood Hits	164	Shared Neighborhood Hits	82
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

CJ078_MOUSE
θ value	θ > 10 (rank : 1125)	NC score	0.094378 (rank : 727)
Query Neighborhood Hits	1024	Target Neighborhood Hits	559	Shared Neighborhood Hits	130
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CJ108_HUMAN
θ value	θ > 10 (rank : 1126)	NC score	0.054922 (rank : 1149)
Query Neighborhood Hits	1024	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CK024_MOUSE
θ value	θ > 10 (rank : 1127)	NC score	0.058542 (rank : 1052)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	92
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CLR59_HUMAN
θ value	θ > 10 (rank : 1128)	NC score	0.158973 (rank : 478)
Query Neighborhood Hits	1024	Target Neighborhood Hits	163	Shared Neighborhood Hits	132
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CMTA1_HUMAN
θ value	θ > 10 (rank : 1129)	NC score	0.112223 (rank : 632)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CMTA2_HUMAN
θ value	θ > 10 (rank : 1130)	NC score	0.096610 (rank : 715)
Query Neighborhood Hits	1024	Target Neighborhood Hits	199	Shared Neighborhood Hits	105
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CNTRB_MOUSE
θ value	θ > 10 (rank : 1131)	NC score	0.050059 (rank : 1285)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1029	Shared Neighborhood Hits	142
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO002_HUMAN
θ value	θ > 10 (rank : 1132)	NC score	0.111994 (rank : 634)
Query Neighborhood Hits	1024	Target Neighborhood Hits	387	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_HUMAN
θ value	θ > 10 (rank : 1133)	NC score	0.076126 (rank : 835)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	110
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO6A1_HUMAN
θ value	θ > 10 (rank : 1134)	NC score	0.137260 (rank : 530)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	94
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A1_MOUSE
θ value	θ > 10 (rank : 1135)	NC score	0.136617 (rank : 534)
Query Neighborhood Hits	1024	Target Neighborhood Hits	241	Shared Neighborhood Hits	89
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A3_HUMAN
θ value	θ > 10 (rank : 1136)	NC score	0.105205 (rank : 668)
Query Neighborhood Hits	1024	Target Neighborhood Hits	317	Shared Neighborhood Hits	98
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

CO9A3_HUMAN
θ value	θ > 10 (rank : 1137)	NC score	0.173390 (rank : 445)
Query Neighborhood Hits	1024	Target Neighborhood Hits	361	Shared Neighborhood Hits	140
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COCA1_HUMAN
θ value	θ > 10 (rank : 1138)	NC score	0.073748 (rank : 858)
Query Neighborhood Hits	1024	Target Neighborhood Hits	458	Shared Neighborhood Hits	103
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_MOUSE
θ value	θ > 10 (rank : 1139)	NC score	0.084166 (rank : 778)
Query Neighborhood Hits	1024	Target Neighborhood Hits	402	Shared Neighborhood Hits	108
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COFA1_HUMAN
θ value	θ > 10 (rank : 1140)	NC score	0.128176 (rank : 570)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	108
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

COFA1_MOUSE
θ value	θ > 10 (rank : 1141)	NC score	0.133021 (rank : 550)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	113
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

COJA1_HUMAN
θ value	θ > 10 (rank : 1142)	NC score	0.159221 (rank : 477)
Query Neighborhood Hits	1024	Target Neighborhood Hits	323	Shared Neighborhood Hits	121
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CONA1_MOUSE
θ value	θ > 10 (rank : 1143)	NC score	0.157238 (rank : 483)
Query Neighborhood Hits	1024	Target Neighborhood Hits	254	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CRK_HUMAN
θ value	θ > 10 (rank : 1144)	NC score	0.202261 (rank : 377)
Query Neighborhood Hits	1024	Target Neighborhood Hits	308	Shared Neighborhood Hits	163
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 1145)	NC score	0.206241 (rank : 373)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	165
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRSP7_HUMAN
θ value	θ > 10 (rank : 1146)	NC score	0.097691 (rank : 706)
Query Neighborhood Hits	1024	Target Neighborhood Hits	247	Shared Neighborhood Hits	112
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CRTC1_HUMAN
θ value	θ > 10 (rank : 1147)	NC score	0.086092 (rank : 764)
Query Neighborhood Hits	1024	Target Neighborhood Hits	319	Shared Neighborhood Hits	150
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CRTC1_MOUSE
θ value	θ > 10 (rank : 1148)	NC score	0.060157 (rank : 1019)
Query Neighborhood Hits	1024	Target Neighborhood Hits	230	Shared Neighborhood Hits	92
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CS016_HUMAN
θ value	θ > 10 (rank : 1149)	NC score	0.102777 (rank : 681)
Query Neighborhood Hits	1024	Target Neighborhood Hits	310	Shared Neighborhood Hits	111
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSF1R_HUMAN
θ value	θ > 10 (rank : 1150)	NC score	0.051790 (rank : 1236)
Query Neighborhood Hits	1024	Target Neighborhood Hits	943	Shared Neighborhood Hits	76
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF1R_MOUSE
θ value	θ > 10 (rank : 1151)	NC score	0.051038 (rank : 1254)
Query Neighborhood Hits	1024	Target Neighborhood Hits	983	Shared Neighborhood Hits	77
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF1_HUMAN
θ value	θ > 10 (rank : 1152)	NC score	0.118304 (rank : 603)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	128
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CSK_HUMAN
θ value	θ > 10 (rank : 1153)	NC score	0.088030 (rank : 751)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1009	Shared Neighborhood Hits	167
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 1154)	NC score	0.087859 (rank : 754)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1009	Shared Neighborhood Hits	167
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CT012_HUMAN
θ value	θ > 10 (rank : 1155)	NC score	0.236469 (rank : 338)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

CTAG2_HUMAN
θ value	θ > 10 (rank : 1156)	NC score	0.060790 (rank : 1011)
Query Neighborhood Hits	1024	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	O75638, O75637, Q9BU80, Q9UJ89, Q9Y479	Gene names	CTAG2, ESO2, LAGE1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 2 (L antigen family member 1) (LAGE-1 protein) (ESO-2 protein).

CTG1B_HUMAN
θ value	θ > 10 (rank : 1157)	NC score	0.067198 (rank : 926)
Query Neighborhood Hits	1024	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	P78358, Q7LBY4	Gene names	CTAG1B, CTAG, CTAG1, ESO1, LAGE2
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 1B (L antigen family member 2) (LAGE-2 protein) (Autoimmunogenic cancer/testis antigen NY-ESO-1).

CTHR1_HUMAN
θ value	θ > 10 (rank : 1158)	NC score	0.106697 (rank : 660)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	64
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
θ value	θ > 10 (rank : 1159)	NC score	0.106409 (rank : 661)
Query Neighborhood Hits	1024	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

CU081_HUMAN
θ value	θ > 10 (rank : 1160)	NC score	0.052474 (rank : 1219)
Query Neighborhood Hits	1024	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DAB1_HUMAN
θ value	θ > 10 (rank : 1161)	NC score	0.052118 (rank : 1229)
Query Neighborhood Hits	1024	Target Neighborhood Hits	219	Shared Neighborhood Hits	83
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DAPP1_HUMAN
θ value	θ > 10 (rank : 1162)	NC score	0.082128 (rank : 790)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 1163)	NC score	0.080730 (rank : 798)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDR1_HUMAN
θ value	θ > 10 (rank : 1164)	NC score	0.056434 (rank : 1102)
Query Neighborhood Hits	1024	Target Neighborhood Hits	819	Shared Neighborhood Hits	79
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 1165)	NC score	0.057458 (rank : 1077)
Query Neighborhood Hits	1024	Target Neighborhood Hits	818	Shared Neighborhood Hits	82
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 1166)	NC score	0.054461 (rank : 1163)
Query Neighborhood Hits	1024	Target Neighborhood Hits	818	Shared Neighborhood Hits	78
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 1167)	NC score	0.053659 (rank : 1185)
Query Neighborhood Hits	1024	Target Neighborhood Hits	813	Shared Neighborhood Hits	76
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DIAP1_MOUSE
θ value	θ > 10 (rank : 1168)	NC score	0.055290 (rank : 1138)
Query Neighborhood Hits	1024	Target Neighborhood Hits	839	Shared Neighborhood Hits	141
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DMRTD_HUMAN
θ value	θ > 10 (rank : 1169)	NC score	0.055258 (rank : 1140)
Query Neighborhood Hits	1024	Target Neighborhood Hits	216	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

DOCK1_HUMAN
θ value	θ > 10 (rank : 1170)	NC score	0.062115 (rank : 988)
Query Neighborhood Hits	1024	Target Neighborhood Hits	191	Shared Neighborhood Hits	107
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DOT1L_HUMAN
θ value	θ > 10 (rank : 1171)	NC score	0.103156 (rank : 674)
Query Neighborhood Hits	1024	Target Neighborhood Hits	660	Shared Neighborhood Hits	166
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

ECM1_HUMAN
θ value	θ > 10 (rank : 1172)	NC score	0.053072 (rank : 1204)
Query Neighborhood Hits	1024	Target Neighborhood Hits	182	Shared Neighborhood Hits	76
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

ECT2_MOUSE
θ value	θ > 10 (rank : 1173)	NC score	0.051701 (rank : 1239)
Query Neighborhood Hits	1024	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EGFR_HUMAN
θ value	θ > 10 (rank : 1174)	NC score	0.054714 (rank : 1157)
Query Neighborhood Hits	1024	Target Neighborhood Hits	939	Shared Neighborhood Hits	84
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 1175)	NC score	0.054944 (rank : 1148)
Query Neighborhood Hits	1024	Target Neighborhood Hits	927	Shared Neighborhood Hits	87
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ELN_HUMAN
θ value	θ > 10 (rank : 1176)	NC score	0.096416 (rank : 716)
Query Neighborhood Hits	1024	Target Neighborhood Hits	85	Shared Neighborhood Hits	39
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

EMIL1_HUMAN
θ value	θ > 10 (rank : 1177)	NC score	0.077573 (rank : 825)
Query Neighborhood Hits	1024	Target Neighborhood Hits	239	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

EMIL1_MOUSE
θ value	θ > 10 (rank : 1178)	NC score	0.076240 (rank : 833)
Query Neighborhood Hits	1024	Target Neighborhood Hits	214	Shared Neighborhood Hits	70
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

EMIL2_HUMAN
θ value	θ > 10 (rank : 1179)	NC score	0.066920 (rank : 932)
Query Neighborhood Hits	1024	Target Neighborhood Hits	573	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

EMIL2_MOUSE
θ value	θ > 10 (rank : 1180)	NC score	0.077373 (rank : 826)
Query Neighborhood Hits	1024	Target Neighborhood Hits	485	Shared Neighborhood Hits	112
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

ENAM_HUMAN
θ value	θ > 10 (rank : 1181)	NC score	0.052219 (rank : 1227)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

ENAM_MOUSE
θ value	θ > 10 (rank : 1182)	NC score	0.057382 (rank : 1079)
Query Neighborhood Hits	1024	Target Neighborhood Hits	229	Shared Neighborhood Hits	78
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

EP400_MOUSE
θ value	θ > 10 (rank : 1183)	NC score	0.052712 (rank : 1213)
Query Neighborhood Hits	1024	Target Neighborhood Hits	592	Shared Neighborhood Hits	169
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EPHA1_HUMAN
θ value	θ > 10 (rank : 1184)	NC score	0.059545 (rank : 1031)
Query Neighborhood Hits	1024	Target Neighborhood Hits	997	Shared Neighborhood Hits	107
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA1_MOUSE
θ value	θ > 10 (rank : 1185)	NC score	0.058684 (rank : 1048)
Query Neighborhood Hits	1024	Target Neighborhood Hits	958	Shared Neighborhood Hits	100
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA2_HUMAN
θ value	θ > 10 (rank : 1186)	NC score	0.057496 (rank : 1075)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1021	Shared Neighborhood Hits	98
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA2_MOUSE
θ value	θ > 10 (rank : 1187)	NC score	0.057547 (rank : 1072)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1020	Shared Neighborhood Hits	97
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA3_HUMAN
θ value	θ > 10 (rank : 1188)	NC score	0.053276 (rank : 1195)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1005	Shared Neighborhood Hits	94
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA3_MOUSE
θ value	θ > 10 (rank : 1189)	NC score	0.053208 (rank : 1200)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1009	Shared Neighborhood Hits	95
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA4_HUMAN
θ value	θ > 10 (rank : 1190)	NC score	0.055228 (rank : 1141)
Query Neighborhood Hits	1024	Target Neighborhood Hits	975	Shared Neighborhood Hits	98
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
θ value	θ > 10 (rank : 1191)	NC score	0.055283 (rank : 1139)
Query Neighborhood Hits	1024	Target Neighborhood Hits	982	Shared Neighborhood Hits	98
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA5_HUMAN
θ value	θ > 10 (rank : 1192)	NC score	0.056855 (rank : 1094)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1009	Shared Neighborhood Hits	104
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA5_MOUSE
θ value	θ > 10 (rank : 1193)	NC score	0.058453 (rank : 1056)
Query Neighborhood Hits	1024	Target Neighborhood Hits	950	Shared Neighborhood Hits	99
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHA6_HUMAN
θ value	θ > 10 (rank : 1194)	NC score	0.057523 (rank : 1073)
Query Neighborhood Hits	1024	Target Neighborhood Hits	959	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA6_MOUSE
θ value	θ > 10 (rank : 1195)	NC score	0.057116 (rank : 1085)
Query Neighborhood Hits	1024	Target Neighborhood Hits	946	Shared Neighborhood Hits	92
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA7_HUMAN
θ value	θ > 10 (rank : 1196)	NC score	0.055608 (rank : 1126)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1053	Shared Neighborhood Hits	104
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA7_MOUSE
θ value	θ > 10 (rank : 1197)	NC score	0.055341 (rank : 1136)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1025	Shared Neighborhood Hits	99
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHA8_HUMAN
θ value	θ > 10 (rank : 1198)	NC score	0.056157 (rank : 1108)
Query Neighborhood Hits	1024	Target Neighborhood Hits	956	Shared Neighborhood Hits	101
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	θ > 10 (rank : 1199)	NC score	0.056993 (rank : 1090)
Query Neighborhood Hits	1024	Target Neighborhood Hits	969	Shared Neighborhood Hits	100
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

EPHAA_HUMAN
θ value	θ > 10 (rank : 1200)	NC score	0.057622 (rank : 1070)
Query Neighborhood Hits	1024	Target Neighborhood Hits	960	Shared Neighborhood Hits	101
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB1_HUMAN
θ value	θ > 10 (rank : 1201)	NC score	0.056196 (rank : 1106)
Query Neighborhood Hits	1024	Target Neighborhood Hits	988	Shared Neighborhood Hits	99
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHB2_HUMAN
θ value	θ > 10 (rank : 1202)	NC score	0.056087 (rank : 1111)
Query Neighborhood Hits	1024	Target Neighborhood Hits	983	Shared Neighborhood Hits	99
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	θ > 10 (rank : 1203)	NC score	0.055863 (rank : 1117)
Query Neighborhood Hits	1024	Target Neighborhood Hits	982	Shared Neighborhood Hits	99
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB3_HUMAN
θ value	θ > 10 (rank : 1204)	NC score	0.057018 (rank : 1089)
Query Neighborhood Hits	1024	Target Neighborhood Hits	996	Shared Neighborhood Hits	105
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB3_MOUSE
θ value	θ > 10 (rank : 1205)	NC score	0.056660 (rank : 1099)
Query Neighborhood Hits	1024	Target Neighborhood Hits	996	Shared Neighborhood Hits	103
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHB4_HUMAN
θ value	θ > 10 (rank : 1206)	NC score	0.058590 (rank : 1050)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1056	Shared Neighborhood Hits	110
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB4_MOUSE
θ value	θ > 10 (rank : 1207)	NC score	0.057905 (rank : 1067)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1013	Shared Neighborhood Hits	106
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHB6_HUMAN
θ value	θ > 10 (rank : 1208)	NC score	0.059055 (rank : 1039)
Query Neighborhood Hits	1024	Target Neighborhood Hits	912	Shared Neighborhood Hits	111
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
θ value	θ > 10 (rank : 1209)	NC score	0.058015 (rank : 1065)
Query Neighborhood Hits	1024	Target Neighborhood Hits	906	Shared Neighborhood Hits	105
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPN3_MOUSE
θ value	θ > 10 (rank : 1210)	NC score	0.067082 (rank : 927)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	134
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

EPS8_HUMAN
θ value	θ > 10 (rank : 1211)	NC score	0.099311 (rank : 700)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	109
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_MOUSE
θ value	θ > 10 (rank : 1212)	NC score	0.102953 (rank : 678)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	116
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ERBB2_HUMAN
θ value	θ > 10 (rank : 1213)	NC score	0.063649 (rank : 968)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1073	Shared Neighborhood Hits	160
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB3_HUMAN
θ value	θ > 10 (rank : 1214)	NC score	0.055032 (rank : 1146)
Query Neighborhood Hits	1024	Target Neighborhood Hits	918	Shared Neighborhood Hits	86
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 1215)	NC score	0.054337 (rank : 1168)
Query Neighborhood Hits	1024	Target Neighborhood Hits	898	Shared Neighborhood Hits	83
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 1216)	NC score	0.057713 (rank : 1069)
Query Neighborhood Hits	1024	Target Neighborhood Hits	910	Shared Neighborhood Hits	90
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ES8L2_HUMAN
θ value	θ > 10 (rank : 1217)	NC score	0.127264 (rank : 575)
Query Neighborhood Hits	1024	Target Neighborhood Hits	193	Shared Neighborhood Hits	135
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L2_MOUSE
θ value	θ > 10 (rank : 1218)	NC score	0.116562 (rank : 610)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	117
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L3_MOUSE
θ value	θ > 10 (rank : 1219)	NC score	0.149351 (rank : 502)
Query Neighborhood Hits	1024	Target Neighborhood Hits	168	Shared Neighborhood Hits	124
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ETV5_MOUSE
θ value	θ > 10 (rank : 1220)	NC score	0.050694 (rank : 1265)
Query Neighborhood Hits	1024	Target Neighborhood Hits	328	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

EVL_HUMAN
θ value	θ > 10 (rank : 1221)	NC score	0.059498 (rank : 1032)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FA47A_HUMAN
θ value	θ > 10 (rank : 1222)	NC score	0.104799 (rank : 671)
Query Neighborhood Hits	1024	Target Neighborhood Hits	451	Shared Neighborhood Hits	167
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 1223)	NC score	0.111424 (rank : 638)
Query Neighborhood Hits	1024	Target Neighborhood Hits	431	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FAK1_HUMAN
θ value	θ > 10 (rank : 1224)	NC score	0.055660 (rank : 1123)
Query Neighborhood Hits	1024	Target Neighborhood Hits	850	Shared Neighborhood Hits	81
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 1225)	NC score	0.055440 (rank : 1132)
Query Neighborhood Hits	1024	Target Neighborhood Hits	850	Shared Neighborhood Hits	79
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 1226)	NC score	0.057489 (rank : 1076)
Query Neighborhood Hits	1024	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 1227)	NC score	0.057929 (rank : 1066)
Query Neighborhood Hits	1024	Target Neighborhood Hits	851	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FCN1_MOUSE
θ value	θ > 10 (rank : 1228)	NC score	0.057238 (rank : 1082)
Query Neighborhood Hits	1024	Target Neighborhood Hits	173	Shared Neighborhood Hits	67
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FER_HUMAN
θ value	θ > 10 (rank : 1229)	NC score	0.069956 (rank : 894)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1278	Shared Neighborhood Hits	130
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FES_HUMAN
θ value	θ > 10 (rank : 1230)	NC score	0.060001 (rank : 1021)
Query Neighborhood Hits	1024	Target Neighborhood Hits	978	Shared Neighborhood Hits	94
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
θ value	θ > 10 (rank : 1231)	NC score	0.058969 (rank : 1041)
Query Neighborhood Hits	1024	Target Neighborhood Hits	980	Shared Neighborhood Hits	93
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FGD3_HUMAN
θ value	θ > 10 (rank : 1232)	NC score	0.056112 (rank : 1109)
Query Neighborhood Hits	1024	Target Neighborhood Hits	249	Shared Neighborhood Hits	63
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 1233)	NC score	0.050474 (rank : 1273)
Query Neighborhood Hits	1024	Target Neighborhood Hits	257	Shared Neighborhood Hits	45
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_MOUSE
θ value	θ > 10 (rank : 1234)	NC score	0.050131 (rank : 1282)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGFR4_HUMAN
θ value	θ > 10 (rank : 1235)	NC score	0.050949 (rank : 1256)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1037	Shared Neighborhood Hits	85
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FGFR4_MOUSE
θ value	θ > 10 (rank : 1236)	NC score	0.052065 (rank : 1230)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1026	Shared Neighborhood Hits	83
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FLT3_HUMAN
θ value	θ > 10 (rank : 1237)	NC score	0.053269 (rank : 1196)
Query Neighborhood Hits	1024	Target Neighborhood Hits	843	Shared Neighborhood Hits	75
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

FLT3_MOUSE
θ value	θ > 10 (rank : 1238)	NC score	0.053412 (rank : 1191)
Query Neighborhood Hits	1024	Target Neighborhood Hits	847	Shared Neighborhood Hits	76
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FMN2_MOUSE
θ value	θ > 10 (rank : 1239)	NC score	0.062298 (rank : 987)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	117
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FOXN1_HUMAN
θ value	θ > 10 (rank : 1240)	NC score	0.061758 (rank : 993)
Query Neighborhood Hits	1024	Target Neighborhood Hits	377	Shared Neighborhood Hits	171
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

FOXN1_MOUSE
θ value	θ > 10 (rank : 1241)	NC score	0.050302 (rank : 1276)
Query Neighborhood Hits	1024	Target Neighborhood Hits	300	Shared Neighborhood Hits	127
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

GIT2_HUMAN
θ value	θ > 10 (rank : 1242)	NC score	0.279782 (rank : 274)
Query Neighborhood Hits	1024	Target Neighborhood Hits	381	Shared Neighborhood Hits	231
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GIT2_MOUSE
θ value	θ > 10 (rank : 1243)	NC score	0.304336 (rank : 254)
Query Neighborhood Hits	1024	Target Neighborhood Hits	323	Shared Neighborhood Hits	237
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GLDN_HUMAN
θ value	θ > 10 (rank : 1244)	NC score	0.105548 (rank : 665)
Query Neighborhood Hits	1024	Target Neighborhood Hits	159	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

GLDN_MOUSE
θ value	θ > 10 (rank : 1245)	NC score	0.101189 (rank : 690)
Query Neighborhood Hits	1024	Target Neighborhood Hits	155	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

GLSK_HUMAN
θ value	θ > 10 (rank : 1246)	NC score	0.314077 (rank : 247)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	176
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GRB10_HUMAN
θ value	θ > 10 (rank : 1247)	NC score	0.050136 (rank : 1281)
Query Neighborhood Hits	1024	Target Neighborhood Hits	147	Shared Neighborhood Hits	52
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	θ > 10 (rank : 1248)	NC score	0.053234 (rank : 1198)
Query Neighborhood Hits	1024	Target Neighborhood Hits	156	Shared Neighborhood Hits	51
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB14_HUMAN
θ value	θ > 10 (rank : 1249)	NC score	0.066518 (rank : 936)
Query Neighborhood Hits	1024	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB14_MOUSE
θ value	θ > 10 (rank : 1250)	NC score	0.066916 (rank : 933)
Query Neighborhood Hits	1024	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_HUMAN
θ value	θ > 10 (rank : 1251)	NC score	0.051867 (rank : 1234)
Query Neighborhood Hits	1024	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB7_MOUSE
θ value	θ > 10 (rank : 1252)	NC score	0.058750 (rank : 1046)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	56
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

GRIN1_MOUSE
θ value	θ > 10 (rank : 1253)	NC score	0.068512 (rank : 910)
Query Neighborhood Hits	1024	Target Neighborhood Hits	337	Shared Neighborhood Hits	103
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GTSE1_HUMAN
θ value	θ > 10 (rank : 1254)	NC score	0.057148 (rank : 1084)
Query Neighborhood Hits	1024	Target Neighborhood Hits	193	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

GTSE1_MOUSE
θ value	θ > 10 (rank : 1255)	NC score	0.065982 (rank : 941)
Query Neighborhood Hits	1024	Target Neighborhood Hits	245	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

GUC2F_HUMAN
θ value	θ > 10 (rank : 1256)	NC score	0.050662 (rank : 1266)
Query Neighborhood Hits	1024	Target Neighborhood Hits	740	Shared Neighborhood Hits	68
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GUC2G_MOUSE
θ value	θ > 10 (rank : 1257)	NC score	0.054922 (rank : 1150)
Query Neighborhood Hits	1024	Target Neighborhood Hits	644	Shared Neighborhood Hits	69
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

HAPIP_HUMAN
θ value	θ > 10 (rank : 1258)	NC score	0.053447 (rank : 1190)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	36
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HECD1_HUMAN
θ value	θ > 10 (rank : 1259)	NC score	0.352336 (rank : 221)
Query Neighborhood Hits	1024	Target Neighborhood Hits	371	Shared Neighborhood Hits	249
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HGS_HUMAN
θ value	θ > 10 (rank : 1260)	NC score	0.054485 (rank : 1161)
Query Neighborhood Hits	1024	Target Neighborhood Hits	517	Shared Neighborhood Hits	101
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	θ > 10 (rank : 1261)	NC score	0.056680 (rank : 1098)
Query Neighborhood Hits	1024	Target Neighborhood Hits	589	Shared Neighborhood Hits	139
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HRBL_HUMAN
θ value	θ > 10 (rank : 1262)	NC score	0.054869 (rank : 1153)
Query Neighborhood Hits	1024	Target Neighborhood Hits	179	Shared Neighborhood Hits	86
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HRBL_MOUSE
θ value	θ > 10 (rank : 1263)	NC score	0.089312 (rank : 745)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	127
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HRX_HUMAN
θ value	θ > 10 (rank : 1264)	NC score	0.073758 (rank : 857)
Query Neighborhood Hits	1024	Target Neighborhood Hits	825	Shared Neighborhood Hits	157
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HSH2D_HUMAN
θ value	θ > 10 (rank : 1265)	NC score	0.059856 (rank : 1026)
Query Neighborhood Hits	1024	Target Neighborhood Hits	159	Shared Neighborhood Hits	44
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

IF4G1_MOUSE
θ value	θ > 10 (rank : 1266)	NC score	0.075041 (rank : 843)
Query Neighborhood Hits	1024	Target Neighborhood Hits	534	Shared Neighborhood Hits	187
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IGF1R_HUMAN
θ value	θ > 10 (rank : 1267)	NC score	0.055170 (rank : 1143)
Query Neighborhood Hits	1024	Target Neighborhood Hits	977	Shared Neighborhood Hits	85
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 1268)	NC score	0.055623 (rank : 1125)
Query Neighborhood Hits	1024	Target Neighborhood Hits	973	Shared Neighborhood Hits	87
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IKBL_HUMAN
θ value	θ > 10 (rank : 1269)	NC score	0.184250 (rank : 420)
Query Neighborhood Hits	1024	Target Neighborhood Hits	168	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	θ > 10 (rank : 1270)	NC score	0.184725 (rank : 417)
Query Neighborhood Hits	1024	Target Neighborhood Hits	196	Shared Neighborhood Hits	144
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IL3B2_MOUSE
θ value	θ > 10 (rank : 1271)	NC score	0.076126 (rank : 836)
Query Neighborhood Hits	1024	Target Neighborhood Hits	372	Shared Neighborhood Hits	170
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL3RB_MOUSE
θ value	θ > 10 (rank : 1272)	NC score	0.072060 (rank : 872)
Query Neighborhood Hits	1024	Target Neighborhood Hits	355	Shared Neighborhood Hits	160
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IL4RA_MOUSE
θ value	θ > 10 (rank : 1273)	NC score	0.060182 (rank : 1018)
Query Neighborhood Hits	1024	Target Neighborhood Hits	194	Shared Neighborhood Hits	75
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

INP5E_HUMAN
θ value	θ > 10 (rank : 1274)	NC score	0.056682 (rank : 1096)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

INSRR_HUMAN
θ value	θ > 10 (rank : 1275)	NC score	0.055943 (rank : 1115)
Query Neighborhood Hits	1024	Target Neighborhood Hits	950	Shared Neighborhood Hits	91
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 1276)	NC score	0.056178 (rank : 1107)
Query Neighborhood Hits	1024	Target Neighborhood Hits	961	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 1277)	NC score	0.054789 (rank : 1156)
Query Neighborhood Hits	1024	Target Neighborhood Hits	963	Shared Neighborhood Hits	86
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 1278)	NC score	0.054171 (rank : 1172)
Query Neighborhood Hits	1024	Target Neighborhood Hits	968	Shared Neighborhood Hits	84
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IRAK1_HUMAN
θ value	θ > 10 (rank : 1279)	NC score	0.055684 (rank : 1122)
Query Neighborhood Hits	1024	Target Neighborhood Hits	820	Shared Neighborhood Hits	95
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	θ > 10 (rank : 1280)	NC score	0.052773 (rank : 1211)
Query Neighborhood Hits	1024	Target Neighborhood Hits	784	Shared Neighborhood Hits	80
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

IRAK2_HUMAN
θ value	θ > 10 (rank : 1281)	NC score	0.055377 (rank : 1133)
Query Neighborhood Hits	1024	Target Neighborhood Hits	714	Shared Neighborhood Hits	76
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

IRAK3_HUMAN
θ value	θ > 10 (rank : 1282)	NC score	0.053269 (rank : 1197)
Query Neighborhood Hits	1024	Target Neighborhood Hits	644	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK3_MOUSE
θ value	θ > 10 (rank : 1283)	NC score	0.053749 (rank : 1182)
Query Neighborhood Hits	1024	Target Neighborhood Hits	628	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IWS1_HUMAN
θ value	θ > 10 (rank : 1284)	NC score	0.074823 (rank : 845)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1241	Shared Neighborhood Hits	200
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 1285)	NC score	0.085583 (rank : 767)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1258	Shared Neighborhood Hits	218
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JADE2_MOUSE
θ value	θ > 10 (rank : 1286)	NC score	0.073222 (rank : 861)
Query Neighborhood Hits	1024	Target Neighborhood Hits	560	Shared Neighborhood Hits	203
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JIP1_HUMAN
θ value	θ > 10 (rank : 1287)	NC score	0.057410 (rank : 1078)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
θ value	θ > 10 (rank : 1288)	NC score	0.059889 (rank : 1025)
Query Neighborhood Hits	1024	Target Neighborhood Hits	259	Shared Neighborhood Hits	119
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP2_HUMAN
θ value	θ > 10 (rank : 1289)	NC score	0.063405 (rank : 971)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	141
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

K0310_HUMAN
θ value	θ > 10 (rank : 1290)	NC score	0.089453 (rank : 743)
Query Neighborhood Hits	1024	Target Neighborhood Hits	420	Shared Neighborhood Hits	163
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1543_HUMAN
θ value	θ > 10 (rank : 1291)	NC score	0.077792 (rank : 823)
Query Neighborhood Hits	1024	Target Neighborhood Hits	435	Shared Neighborhood Hits	170
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1543_MOUSE
θ value	θ > 10 (rank : 1292)	NC score	0.084434 (rank : 774)
Query Neighborhood Hits	1024	Target Neighborhood Hits	497	Shared Neighborhood Hits	178
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1683_HUMAN
θ value	θ > 10 (rank : 1293)	NC score	0.059998 (rank : 1022)
Query Neighborhood Hits	1024	Target Neighborhood Hits	240	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

K1688_HUMAN
θ value	θ > 10 (rank : 1294)	NC score	0.067860 (rank : 918)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	78
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

KI67_HUMAN
θ value	θ > 10 (rank : 1295)	NC score	0.056287 (rank : 1103)
Query Neighborhood Hits	1024	Target Neighborhood Hits	581	Shared Neighborhood Hits	107
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KIT_HUMAN
θ value	θ > 10 (rank : 1296)	NC score	0.052777 (rank : 1209)
Query Neighborhood Hits	1024	Target Neighborhood Hits	953	Shared Neighborhood Hits	77
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 1297)	NC score	0.053087 (rank : 1203)
Query Neighborhood Hits	1024	Target Neighborhood Hits	949	Shared Neighborhood Hits	78
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KSR1_HUMAN
θ value	θ > 10 (rank : 1298)	NC score	0.050225 (rank : 1279)
Query Neighborhood Hits	1024	Target Neighborhood Hits	867	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

KSR2_HUMAN
θ value	θ > 10 (rank : 1299)	NC score	0.054895 (rank : 1152)
Query Neighborhood Hits	1024	Target Neighborhood Hits	920	Shared Neighborhood Hits	122
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

KSYK_HUMAN
θ value	θ > 10 (rank : 1300)	NC score	0.061180 (rank : 1006)
Query Neighborhood Hits	1024	Target Neighborhood Hits	901	Shared Neighborhood Hits	95
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 1301)	NC score	0.062728 (rank : 984)
Query Neighborhood Hits	1024	Target Neighborhood Hits	944	Shared Neighborhood Hits	113
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAD1_HUMAN
θ value	θ > 10 (rank : 1302)	NC score	0.062994 (rank : 976)
Query Neighborhood Hits	1024	Target Neighborhood Hits	441	Shared Neighborhood Hits	111
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LAD1_MOUSE
θ value	θ > 10 (rank : 1303)	NC score	0.073690 (rank : 859)
Query Neighborhood Hits	1024	Target Neighborhood Hits	391	Shared Neighborhood Hits	99
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LARP4_MOUSE
θ value	θ > 10 (rank : 1304)	NC score	0.050476 (rank : 1272)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LCP2_HUMAN
θ value	θ > 10 (rank : 1305)	NC score	0.174176 (rank : 444)
Query Neighborhood Hits	1024	Target Neighborhood Hits	531	Shared Neighborhood Hits	230
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LCP2_MOUSE
θ value	θ > 10 (rank : 1306)	NC score	0.068180 (rank : 914)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	65
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LEUK_HUMAN
θ value	θ > 10 (rank : 1307)	NC score	0.051813 (rank : 1235)
Query Neighborhood Hits	1024	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LNK_HUMAN
θ value	θ > 10 (rank : 1308)	NC score	0.055364 (rank : 1135)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LR37A_HUMAN
θ value	θ > 10 (rank : 1309)	NC score	0.069945 (rank : 895)
Query Neighborhood Hits	1024	Target Neighborhood Hits	720	Shared Neighborhood Hits	150
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LRRK1_HUMAN
θ value	θ > 10 (rank : 1310)	NC score	0.065183 (rank : 950)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1237	Shared Neighborhood Hits	158
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LRRK1_MOUSE
θ value	θ > 10 (rank : 1311)	NC score	0.078357 (rank : 820)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1267	Shared Neighborhood Hits	179
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LSD1_HUMAN
θ value	θ > 10 (rank : 1312)	NC score	0.064502 (rank : 958)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	162
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LTK_HUMAN
θ value	θ > 10 (rank : 1313)	NC score	0.059565 (rank : 1030)
Query Neighborhood Hits	1024	Target Neighborhood Hits	774	Shared Neighborhood Hits	78
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 1314)	NC score	0.058725 (rank : 1047)
Query Neighborhood Hits	1024	Target Neighborhood Hits	770	Shared Neighborhood Hits	81
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

M3K12_HUMAN
θ value	θ > 10 (rank : 1315)	NC score	0.054386 (rank : 1165)
Query Neighborhood Hits	1024	Target Neighborhood Hits	940	Shared Neighborhood Hits	114
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	θ > 10 (rank : 1316)	NC score	0.054020 (rank : 1175)
Query Neighborhood Hits	1024	Target Neighborhood Hits	957	Shared Neighborhood Hits	112
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K13_HUMAN
θ value	θ > 10 (rank : 1317)	NC score	0.051342 (rank : 1246)
Query Neighborhood Hits	1024	Target Neighborhood Hits	911	Shared Neighborhood Hits	91
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M3K7_MOUSE
θ value	θ > 10 (rank : 1318)	NC score	0.050065 (rank : 1284)
Query Neighborhood Hits	1024	Target Neighborhood Hits	892	Shared Neighborhood Hits	78
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

MADCA_HUMAN
θ value	θ > 10 (rank : 1319)	NC score	0.063156 (rank : 973)
Query Neighborhood Hits	1024	Target Neighborhood Hits	221	Shared Neighborhood Hits	70
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAML3_HUMAN
θ value	θ > 10 (rank : 1320)	NC score	0.080414 (rank : 801)
Query Neighborhood Hits	1024	Target Neighborhood Hits	323	Shared Neighborhood Hits	115
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MAP4_MOUSE
θ value	θ > 10 (rank : 1321)	NC score	0.063916 (rank : 966)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	99
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCO_HUMAN
θ value	θ > 10 (rank : 1322)	NC score	0.116273 (rank : 612)
Query Neighborhood Hits	1024	Target Neighborhood Hits	199	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

MARCO_MOUSE
θ value	θ > 10 (rank : 1323)	NC score	0.134988 (rank : 539)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	83
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

MATK_HUMAN
θ value	θ > 10 (rank : 1324)	NC score	0.074148 (rank : 853)
Query Neighborhood Hits	1024	Target Neighborhood Hits	954	Shared Neighborhood Hits	115
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MAVS_HUMAN
θ value	θ > 10 (rank : 1325)	NC score	0.068933 (rank : 906)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	106
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MBD6_HUMAN
θ value	θ > 10 (rank : 1326)	NC score	0.126839 (rank : 577)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	125
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MBL1_MOUSE
θ value	θ > 10 (rank : 1327)	NC score	0.067321 (rank : 924)
Query Neighborhood Hits	1024	Target Neighborhood Hits	147	Shared Neighborhood Hits	48
SwissProt Accessions	P39039	Gene names	Mbl1
Domain Architecture
Description	Mannose-binding protein A precursor (MBP-A) (Mannan-binding protein) (Ra-reactive factor polysaccharide-binding component p28B polypeptide) (RaRF p28B).

MBL2_HUMAN
θ value	θ > 10 (rank : 1328)	NC score	0.072535 (rank : 869)
Query Neighborhood Hits	1024	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	P11226, Q86SI4, Q96KE4, Q96TF7, Q96TF8, Q96TF9	Gene names	MBL2, MBL
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (MBP1) (Mannan-binding protein) (Mannose-binding lectin).

MBL2_MOUSE
θ value	θ > 10 (rank : 1329)	NC score	0.068009 (rank : 917)
Query Neighborhood Hits	1024	Target Neighborhood Hits	148	Shared Neighborhood Hits	46
SwissProt Accessions	P41317	Gene names	Mbl2
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (Mannan-binding protein) (RA-reactive factor P28A subunit) (RARF/P28A).

MCF2L_MOUSE
θ value	θ > 10 (rank : 1330)	NC score	0.073124 (rank : 863)
Query Neighborhood Hits	1024	Target Neighborhood Hits	255	Shared Neighborhood Hits	54
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 1331)	NC score	0.059919 (rank : 1024)
Query Neighborhood Hits	1024	Target Neighborhood Hits	166	Shared Neighborhood Hits	31
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MEF2B_MOUSE
θ value	θ > 10 (rank : 1332)	NC score	0.068618 (rank : 908)
Query Neighborhood Hits	1024	Target Neighborhood Hits	218	Shared Neighborhood Hits	127
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MERTK_HUMAN
θ value	θ > 10 (rank : 1333)	NC score	0.055314 (rank : 1137)
Query Neighborhood Hits	1024	Target Neighborhood Hits	988	Shared Neighborhood Hits	88
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	θ > 10 (rank : 1334)	NC score	0.055709 (rank : 1121)
Query Neighborhood Hits	1024	Target Neighborhood Hits	974	Shared Neighborhood Hits	86
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MET_HUMAN
θ value	θ > 10 (rank : 1335)	NC score	0.054587 (rank : 1159)
Query Neighborhood Hits	1024	Target Neighborhood Hits	831	Shared Neighborhood Hits	77
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 1336)	NC score	0.054845 (rank : 1154)
Query Neighborhood Hits	1024	Target Neighborhood Hits	844	Shared Neighborhood Hits	79
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MILK1_MOUSE
θ value	θ > 10 (rank : 1337)	NC score	0.101988 (rank : 684)
Query Neighborhood Hits	1024	Target Neighborhood Hits	788	Shared Neighborhood Hits	262
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MLKL_HUMAN
θ value	θ > 10 (rank : 1338)	NC score	0.061460 (rank : 1000)
Query Neighborhood Hits	1024	Target Neighborhood Hits	600	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 1339)	NC score	0.057101 (rank : 1086)
Query Neighborhood Hits	1024	Target Neighborhood Hits	707	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLL3_MOUSE
θ value	θ > 10 (rank : 1340)	NC score	0.139275 (rank : 524)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1399	Shared Neighborhood Hits	332
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLTK_HUMAN
θ value	θ > 10 (rank : 1341)	NC score	0.053996 (rank : 1178)
Query Neighborhood Hits	1024	Target Neighborhood Hits	911	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
θ value	θ > 10 (rank : 1342)	NC score	0.053198 (rank : 1201)
Query Neighborhood Hits	1024	Target Neighborhood Hits	874	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MN1_HUMAN
θ value	θ > 10 (rank : 1343)	NC score	0.054827 (rank : 1155)
Query Neighborhood Hits	1024	Target Neighborhood Hits	196	Shared Neighborhood Hits	72
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

MNT_HUMAN
θ value	θ > 10 (rank : 1344)	NC score	0.084386 (rank : 776)
Query Neighborhood Hits	1024	Target Neighborhood Hits	496	Shared Neighborhood Hits	157
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	θ > 10 (rank : 1345)	NC score	0.071798 (rank : 875)
Query Neighborhood Hits	1024	Target Neighborhood Hits	432	Shared Neighborhood Hits	115
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MOS_HUMAN
θ value	θ > 10 (rank : 1346)	NC score	0.055528 (rank : 1129)
Query Neighborhood Hits	1024	Target Neighborhood Hits	829	Shared Neighborhood Hits	77
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MOS_MOUSE
θ value	θ > 10 (rank : 1347)	NC score	0.055762 (rank : 1119)
Query Neighborhood Hits	1024	Target Neighborhood Hits	833	Shared Neighborhood Hits	79
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MSRE_HUMAN
θ value	θ > 10 (rank : 1348)	NC score	0.100619 (rank : 695)
Query Neighborhood Hits	1024	Target Neighborhood Hits	298	Shared Neighborhood Hits	74
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

MSRE_MOUSE
θ value	θ > 10 (rank : 1349)	NC score	0.084066 (rank : 781)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	73
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

MTSS1_HUMAN
θ value	θ > 10 (rank : 1350)	NC score	0.100435 (rank : 697)
Query Neighborhood Hits	1024	Target Neighborhood Hits	504	Shared Neighborhood Hits	166
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MUC13_MOUSE
θ value	θ > 10 (rank : 1351)	NC score	0.050584 (rank : 1268)
Query Neighborhood Hits	1024	Target Neighborhood Hits	447	Shared Neighborhood Hits	79
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	θ > 10 (rank : 1352)	NC score	0.076411 (rank : 832)
Query Neighborhood Hits	1024	Target Neighborhood Hits	388	Shared Neighborhood Hits	78
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 1353)	NC score	0.071890 (rank : 874)
Query Neighborhood Hits	1024	Target Neighborhood Hits	906	Shared Neighborhood Hits	154
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 1354)	NC score	0.068997 (rank : 904)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1020	Shared Neighborhood Hits	169
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUSK_HUMAN
θ value	θ > 10 (rank : 1355)	NC score	0.051168 (rank : 1251)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1074	Shared Neighborhood Hits	79
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 1356)	NC score	0.050924 (rank : 1259)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1057	Shared Neighborhood Hits	79
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MY18B_HUMAN
θ value	θ > 10 (rank : 1357)	NC score	0.057616 (rank : 1071)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1299	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

NCF2_HUMAN
θ value	θ > 10 (rank : 1358)	NC score	0.237698 (rank : 337)
Query Neighborhood Hits	1024	Target Neighborhood Hits	229	Shared Neighborhood Hits	147
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCF4_HUMAN
θ value	θ > 10 (rank : 1359)	NC score	0.182211 (rank : 428)
Query Neighborhood Hits	1024	Target Neighborhood Hits	161	Shared Neighborhood Hits	117
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 1360)	NC score	0.195231 (rank : 389)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	131
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCOA6_MOUSE
θ value	θ > 10 (rank : 1361)	NC score	0.181548 (rank : 432)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1076	Shared Neighborhood Hits	368
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOR2_HUMAN
θ value	θ > 10 (rank : 1362)	NC score	0.075607 (rank : 841)
Query Neighborhood Hits	1024	Target Neighborhood Hits	870	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NFAC1_HUMAN
θ value	θ > 10 (rank : 1363)	NC score	0.051457 (rank : 1244)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	130
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NFH_MOUSE
θ value	θ > 10 (rank : 1364)	NC score	0.146817 (rank : 503)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2247	Shared Neighborhood Hits	450
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NFRKB_MOUSE
θ value	θ > 10 (rank : 1365)	NC score	0.070286 (rank : 889)
Query Neighborhood Hits	1024	Target Neighborhood Hits	393	Shared Neighborhood Hits	135
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NGEF_HUMAN
θ value	θ > 10 (rank : 1366)	NC score	0.074714 (rank : 847)
Query Neighborhood Hits	1024	Target Neighborhood Hits	166	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
θ value	θ > 10 (rank : 1367)	NC score	0.079563 (rank : 811)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NOLC1_HUMAN
θ value	θ > 10 (rank : 1368)	NC score	0.054107 (rank : 1173)
Query Neighborhood Hits	1024	Target Neighborhood Hits	452	Shared Neighborhood Hits	78
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NOXO1_HUMAN
θ value	θ > 10 (rank : 1369)	NC score	0.119574 (rank : 596)
Query Neighborhood Hits	1024	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 1370)	NC score	0.143612 (rank : 509)
Query Neighborhood Hits	1024	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHP1_MOUSE
θ value	θ > 10 (rank : 1371)	NC score	0.211630 (rank : 365)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NRX2A_HUMAN
θ value	θ > 10 (rank : 1372)	NC score	0.094423 (rank : 726)
Query Neighborhood Hits	1024	Target Neighborhood Hits	614	Shared Neighborhood Hits	255
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	θ > 10 (rank : 1373)	NC score	0.137049 (rank : 531)
Query Neighborhood Hits	1024	Target Neighborhood Hits	481	Shared Neighborhood Hits	245
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

NSD1_HUMAN
θ value	θ > 10 (rank : 1374)	NC score	0.050837 (rank : 1262)
Query Neighborhood Hits	1024	Target Neighborhood Hits	427	Shared Neighborhood Hits	86
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NTRK1_HUMAN
θ value	θ > 10 (rank : 1375)	NC score	0.054361 (rank : 1167)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1023	Shared Neighborhood Hits	81
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 1376)	NC score	0.051108 (rank : 1252)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1081	Shared Neighborhood Hits	84
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 1377)	NC score	0.051058 (rank : 1253)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1088	Shared Neighborhood Hits	84
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 1378)	NC score	0.052306 (rank : 1224)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1115	Shared Neighborhood Hits	85
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

NUD12_HUMAN
θ value	θ > 10 (rank : 1379)	NC score	0.294395 (rank : 262)
Query Neighborhood Hits	1024	Target Neighborhood Hits	222	Shared Neighborhood Hits	190
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

NUD12_MOUSE
θ value	θ > 10 (rank : 1380)	NC score	0.312133 (rank : 248)
Query Neighborhood Hits	1024	Target Neighborhood Hits	243	Shared Neighborhood Hits	207
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

NUMBL_HUMAN
θ value	θ > 10 (rank : 1381)	NC score	0.079265 (rank : 815)
Query Neighborhood Hits	1024	Target Neighborhood Hits	394	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NUP53_HUMAN
θ value	θ > 10 (rank : 1382)	NC score	0.057238 (rank : 1083)
Query Neighborhood Hits	1024	Target Neighborhood Hits	156	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

OBF1_HUMAN
θ value	θ > 10 (rank : 1383)	NC score	0.059031 (rank : 1040)
Query Neighborhood Hits	1024	Target Neighborhood Hits	203	Shared Neighborhood Hits	94
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

OGFR_MOUSE
θ value	θ > 10 (rank : 1384)	NC score	0.188743 (rank : 406)
Query Neighborhood Hits	1024	Target Neighborhood Hits	584	Shared Neighborhood Hits	190
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

P55G_HUMAN
θ value	θ > 10 (rank : 1385)	NC score	0.067845 (rank : 919)
Query Neighborhood Hits	1024	Target Neighborhood Hits	451	Shared Neighborhood Hits	75
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 1386)	NC score	0.060122 (rank : 1020)
Query Neighborhood Hits	1024	Target Neighborhood Hits	401	Shared Neighborhood Hits	66
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85A_HUMAN
θ value	θ > 10 (rank : 1387)	NC score	0.082104 (rank : 791)
Query Neighborhood Hits	1024	Target Neighborhood Hits	479	Shared Neighborhood Hits	117
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	θ > 10 (rank : 1388)	NC score	0.086147 (rank : 763)
Query Neighborhood Hits	1024	Target Neighborhood Hits	435	Shared Neighborhood Hits	120
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 1389)	NC score	0.072882 (rank : 867)
Query Neighborhood Hits	1024	Target Neighborhood Hits	543	Shared Neighborhood Hits	107
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 1390)	NC score	0.071121 (rank : 879)
Query Neighborhood Hits	1024	Target Neighborhood Hits	519	Shared Neighborhood Hits	99
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PAR10_HUMAN
θ value	θ > 10 (rank : 1391)	NC score	0.065696 (rank : 948)
Query Neighborhood Hits	1024	Target Neighborhood Hits	142	Shared Neighborhood Hits	67
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PCQAP_HUMAN
θ value	θ > 10 (rank : 1392)	NC score	0.087926 (rank : 753)
Query Neighborhood Hits	1024	Target Neighborhood Hits	549	Shared Neighborhood Hits	127
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PDC6I_HUMAN
θ value	θ > 10 (rank : 1393)	NC score	0.052574 (rank : 1217)
Query Neighborhood Hits	1024	Target Neighborhood Hits	278	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDZD2_HUMAN
θ value	θ > 10 (rank : 1394)	NC score	0.073084 (rank : 865)
Query Neighborhood Hits	1024	Target Neighborhood Hits	772	Shared Neighborhood Hits	192
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PER2_MOUSE
θ value	θ > 10 (rank : 1395)	NC score	0.050658 (rank : 1267)
Query Neighborhood Hits	1024	Target Neighborhood Hits	325	Shared Neighborhood Hits	117
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PER3_HUMAN
θ value	θ > 10 (rank : 1396)	NC score	0.074483 (rank : 849)
Query Neighborhood Hits	1024	Target Neighborhood Hits	479	Shared Neighborhood Hits	184
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PGCA_HUMAN
θ value	θ > 10 (rank : 1397)	NC score	0.085589 (rank : 766)
Query Neighborhood Hits	1024	Target Neighborhood Hits	821	Shared Neighborhood Hits	143
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGFRA_HUMAN
θ value	θ > 10 (rank : 1398)	NC score	0.053006 (rank : 1205)
Query Neighborhood Hits	1024	Target Neighborhood Hits	980	Shared Neighborhood Hits	82
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
θ value	θ > 10 (rank : 1399)	NC score	0.053002 (rank : 1206)
Query Neighborhood Hits	1024	Target Neighborhood Hits	975	Shared Neighborhood Hits	80
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_HUMAN
θ value	θ > 10 (rank : 1400)	NC score	0.052362 (rank : 1223)
Query Neighborhood Hits	1024	Target Neighborhood Hits	962	Shared Neighborhood Hits	82
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
θ value	θ > 10 (rank : 1401)	NC score	0.052672 (rank : 1215)
Query Neighborhood Hits	1024	Target Neighborhood Hits	960	Shared Neighborhood Hits	81
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PHLB1_HUMAN
θ value	θ > 10 (rank : 1402)	NC score	0.072305 (rank : 870)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1038	Shared Neighborhood Hits	203
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA6_HUMAN
θ value	θ > 10 (rank : 1403)	NC score	0.078449 (rank : 819)
Query Neighborhood Hits	1024	Target Neighborhood Hits	556	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 1404)	NC score	0.073130 (rank : 862)
Query Neighborhood Hits	1024	Target Neighborhood Hits	591	Shared Neighborhood Hits	162
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHG1_HUMAN
θ value	θ > 10 (rank : 1405)	NC score	0.076052 (rank : 837)
Query Neighborhood Hits	1024	Target Neighborhood Hits	174	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PKHG4_HUMAN
θ value	θ > 10 (rank : 1406)	NC score	0.073626 (rank : 860)
Query Neighborhood Hits	1024	Target Neighborhood Hits	200	Shared Neighborhood Hits	91
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PO121_HUMAN
θ value	θ > 10 (rank : 1407)	NC score	0.061465 (rank : 999)
Query Neighborhood Hits	1024	Target Neighborhood Hits	344	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PP1RA_HUMAN
θ value	θ > 10 (rank : 1408)	NC score	0.066935 (rank : 931)
Query Neighborhood Hits	1024	Target Neighborhood Hits	180	Shared Neighborhood Hits	68
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

PP1RA_MOUSE
θ value	θ > 10 (rank : 1409)	NC score	0.056948 (rank : 1092)
Query Neighborhood Hits	1024	Target Neighborhood Hits	175	Shared Neighborhood Hits	67
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

PREX1_HUMAN
θ value	θ > 10 (rank : 1410)	NC score	0.069611 (rank : 899)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRG4_HUMAN
θ value	θ > 10 (rank : 1411)	NC score	0.105912 (rank : 663)
Query Neighborhood Hits	1024	Target Neighborhood Hits	764	Shared Neighborhood Hits	168
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 1412)	NC score	0.084962 (rank : 771)
Query Neighborhood Hits	1024	Target Neighborhood Hits	624	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP5_HUMAN
θ value	θ > 10 (rank : 1413)	NC score	0.119113 (rank : 598)
Query Neighborhood Hits	1024	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPE_HUMAN
θ value	θ > 10 (rank : 1414)	NC score	0.088538 (rank : 748)
Query Neighborhood Hits	1024	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR8_HUMAN
θ value	θ > 10 (rank : 1415)	NC score	0.054385 (rank : 1166)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

RAF1_HUMAN
θ value	θ > 10 (rank : 1416)	NC score	0.053285 (rank : 1194)
Query Neighborhood Hits	1024	Target Neighborhood Hits	886	Shared Neighborhood Hits	88
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	θ > 10 (rank : 1417)	NC score	0.052727 (rank : 1212)
Query Neighborhood Hits	1024	Target Neighborhood Hits	886	Shared Neighborhood Hits	89
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RASA1_HUMAN
θ value	θ > 10 (rank : 1418)	NC score	0.085227 (rank : 770)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	69
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RBM12_HUMAN
θ value	θ > 10 (rank : 1419)	NC score	0.051534 (rank : 1242)
Query Neighborhood Hits	1024	Target Neighborhood Hits	298	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM12_MOUSE
θ value	θ > 10 (rank : 1420)	NC score	0.060230 (rank : 1017)
Query Neighborhood Hits	1024	Target Neighborhood Hits	313	Shared Neighborhood Hits	104
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM16_HUMAN
θ value	θ > 10 (rank : 1421)	NC score	0.050404 (rank : 1274)
Query Neighborhood Hits	1024	Target Neighborhood Hits	300	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

REL_MOUSE
θ value	θ > 10 (rank : 1422)	NC score	0.051681 (rank : 1240)
Query Neighborhood Hits	1024	Target Neighborhood Hits	77	Shared Neighborhood Hits	25
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

RET_HUMAN
θ value	θ > 10 (rank : 1423)	NC score	0.054006 (rank : 1177)
Query Neighborhood Hits	1024	Target Neighborhood Hits	873	Shared Neighborhood Hits	74
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 1424)	NC score	0.054466 (rank : 1162)
Query Neighborhood Hits	1024	Target Neighborhood Hits	884	Shared Neighborhood Hits	77
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RGNEF_MOUSE
θ value	θ > 10 (rank : 1425)	NC score	0.051319 (rank : 1248)
Query Neighborhood Hits	1024	Target Neighborhood Hits	641	Shared Neighborhood Hits	75
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RGS3_HUMAN
θ value	θ > 10 (rank : 1426)	NC score	0.146379 (rank : 505)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1375	Shared Neighborhood Hits	388
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	θ > 10 (rank : 1427)	NC score	0.205468 (rank : 375)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1621	Shared Neighborhood Hits	481
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RIN3_MOUSE
θ value	θ > 10 (rank : 1428)	NC score	0.053490 (rank : 1189)
Query Neighborhood Hits	1024	Target Neighborhood Hits	239	Shared Neighborhood Hits	87
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIPK1_HUMAN
θ value	θ > 10 (rank : 1429)	NC score	0.052225 (rank : 1226)
Query Neighborhood Hits	1024	Target Neighborhood Hits	891	Shared Neighborhood Hits	87
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_MOUSE
θ value	θ > 10 (rank : 1430)	NC score	0.051704 (rank : 1238)
Query Neighborhood Hits	1024	Target Neighborhood Hits	874	Shared Neighborhood Hits	86
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK2_HUMAN
θ value	θ > 10 (rank : 1431)	NC score	0.055014 (rank : 1147)
Query Neighborhood Hits	1024	Target Neighborhood Hits	774	Shared Neighborhood Hits	72
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	θ > 10 (rank : 1432)	NC score	0.052274 (rank : 1225)
Query Neighborhood Hits	1024	Target Neighborhood Hits	776	Shared Neighborhood Hits	71
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK3_MOUSE
θ value	θ > 10 (rank : 1433)	NC score	0.055214 (rank : 1142)
Query Neighborhood Hits	1024	Target Neighborhood Hits	867	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

RON_HUMAN
θ value	θ > 10 (rank : 1434)	NC score	0.055977 (rank : 1113)
Query Neighborhood Hits	1024	Target Neighborhood Hits	842	Shared Neighborhood Hits	79
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 1435)	NC score	0.056463 (rank : 1101)
Query Neighborhood Hits	1024	Target Neighborhood Hits	836	Shared Neighborhood Hits	73
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 1436)	NC score	0.053521 (rank : 1188)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1018	Shared Neighborhood Hits	82
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 1437)	NC score	0.053523 (rank : 1187)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1025	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 1438)	NC score	0.054080 (rank : 1174)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1014	Shared Neighborhood Hits	84
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 1439)	NC score	0.055572 (rank : 1128)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1000	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

ROS_HUMAN
θ value	θ > 10 (rank : 1440)	NC score	0.058498 (rank : 1054)
Query Neighborhood Hits	1024	Target Neighborhood Hits	907	Shared Neighborhood Hits	85
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

RPTN_HUMAN
θ value	θ > 10 (rank : 1441)	NC score	0.065748 (rank : 947)
Query Neighborhood Hits	1024	Target Neighborhood Hits	406	Shared Neighborhood Hits	88
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

RPTN_MOUSE
θ value	θ > 10 (rank : 1442)	NC score	0.110148 (rank : 644)
Query Neighborhood Hits	1024	Target Neighborhood Hits	650	Shared Neighborhood Hits	119
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RRBP1_MOUSE
θ value	θ > 10 (rank : 1443)	NC score	0.068343 (rank : 912)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1650	Shared Neighborhood Hits	190
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RSNL2_HUMAN
θ value	θ > 10 (rank : 1444)	NC score	0.117931 (rank : 604)
Query Neighborhood Hits	1024	Target Neighborhood Hits	136	Shared Neighborhood Hits	107
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	θ > 10 (rank : 1445)	NC score	0.100839 (rank : 692)
Query Neighborhood Hits	1024	Target Neighborhood Hits	129	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RTP3_MOUSE
θ value	θ > 10 (rank : 1446)	NC score	0.077610 (rank : 824)
Query Neighborhood Hits	1024	Target Neighborhood Hits	374	Shared Neighborhood Hits	139
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RUSC2_HUMAN
θ value	θ > 10 (rank : 1447)	NC score	0.080867 (rank : 797)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RYK_HUMAN
θ value	θ > 10 (rank : 1448)	NC score	0.058951 (rank : 1042)
Query Neighborhood Hits	1024	Target Neighborhood Hits	701	Shared Neighborhood Hits	66
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 1449)	NC score	0.058299 (rank : 1057)
Query Neighborhood Hits	1024	Target Neighborhood Hits	715	Shared Neighborhood Hits	67
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

S23IP_MOUSE
θ value	θ > 10 (rank : 1450)	NC score	0.093775 (rank : 729)
Query Neighborhood Hits	1024	Target Neighborhood Hits	363	Shared Neighborhood Hits	154
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SASH1_MOUSE
θ value	θ > 10 (rank : 1451)	NC score	0.066405 (rank : 938)
Query Neighborhood Hits	1024	Target Neighborhood Hits	263	Shared Neighborhood Hits	100
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SC24A_MOUSE
θ value	θ > 10 (rank : 1452)	NC score	0.085408 (rank : 769)
Query Neighborhood Hits	1024	Target Neighborhood Hits	394	Shared Neighborhood Hits	178
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SELPL_MOUSE
θ value	θ > 10 (rank : 1453)	NC score	0.120191 (rank : 592)
Query Neighborhood Hits	1024	Target Neighborhood Hits	588	Shared Neighborhood Hits	186
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SETBP_MOUSE
θ value	θ > 10 (rank : 1454)	NC score	0.051365 (rank : 1245)
Query Neighborhood Hits	1024	Target Neighborhood Hits	352	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SF01_MOUSE
θ value	θ > 10 (rank : 1455)	NC score	0.058788 (rank : 1044)
Query Neighborhood Hits	1024	Target Neighborhood Hits	240	Shared Neighborhood Hits	93
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A2_MOUSE
θ value	θ > 10 (rank : 1456)	NC score	0.107336 (rank : 657)
Query Neighborhood Hits	1024	Target Neighborhood Hits	247	Shared Neighborhood Hits	111
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3B1_HUMAN
θ value	θ > 10 (rank : 1457)	NC score	0.065883 (rank : 942)
Query Neighborhood Hits	1024	Target Neighborhood Hits	341	Shared Neighborhood Hits	134
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	θ > 10 (rank : 1458)	NC score	0.067340 (rank : 923)
Query Neighborhood Hits	1024	Target Neighborhood Hits	352	Shared Neighborhood Hits	141
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SFTA1_HUMAN
θ value	θ > 10 (rank : 1459)	NC score	0.079391 (rank : 813)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IWL2, P07714, Q5RIR5, Q5RIR7, Q6PIT0, Q8TC19	Gene names	SFTPA1, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A1 precursor (SP-A1) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

SFTA2_HUMAN
θ value	θ > 10 (rank : 1460)	NC score	0.080273 (rank : 806)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IWL1, P07714, Q5RIR8, Q5RIR9	Gene names	SFTPA2, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A2 precursor (SP-A2) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

SFTPA_MOUSE
θ value	θ > 10 (rank : 1461)	NC score	0.086587 (rank : 760)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	54
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

SH21A_HUMAN
θ value	θ > 10 (rank : 1462)	NC score	0.059215 (rank : 1037)
Query Neighborhood Hits	1024	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 1463)	NC score	0.061472 (rank : 998)
Query Neighborhood Hits	1024	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
θ value	θ > 10 (rank : 1464)	NC score	0.083547 (rank : 784)
Query Neighborhood Hits	1024	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 1465)	NC score	0.089224 (rank : 746)
Query Neighborhood Hits	1024	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH24A_HUMAN
θ value	θ > 10 (rank : 1466)	NC score	0.050245 (rank : 1278)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

SHAN2_MOUSE
θ value	θ > 10 (rank : 1467)	NC score	0.110079 (rank : 646)
Query Neighborhood Hits	1024	Target Neighborhood Hits	446	Shared Neighborhood Hits	169
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SHB_HUMAN
θ value	θ > 10 (rank : 1468)	NC score	0.057063 (rank : 1087)
Query Neighborhood Hits	1024	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHB_MOUSE
θ value	θ > 10 (rank : 1469)	NC score	0.058262 (rank : 1059)
Query Neighborhood Hits	1024	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHC1_HUMAN
θ value	θ > 10 (rank : 1470)	NC score	0.063900 (rank : 967)
Query Neighborhood Hits	1024	Target Neighborhood Hits	170	Shared Neighborhood Hits	64
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	θ > 10 (rank : 1471)	NC score	0.061536 (rank : 997)
Query Neighborhood Hits	1024	Target Neighborhood Hits	180	Shared Neighborhood Hits	66
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_HUMAN
θ value	θ > 10 (rank : 1472)	NC score	0.064723 (rank : 956)
Query Neighborhood Hits	1024	Target Neighborhood Hits	170	Shared Neighborhood Hits	66
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 1473)	NC score	0.059313 (rank : 1034)
Query Neighborhood Hits	1024	Target Neighborhood Hits	144	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC3_HUMAN
θ value	θ > 10 (rank : 1474)	NC score	0.056932 (rank : 1093)
Query Neighborhood Hits	1024	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 1475)	NC score	0.061253 (rank : 1002)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHD_HUMAN
θ value	θ > 10 (rank : 1476)	NC score	0.063370 (rank : 972)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHD_MOUSE
θ value	θ > 10 (rank : 1477)	NC score	0.056219 (rank : 1104)
Query Neighborhood Hits	1024	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHE_HUMAN
θ value	θ > 10 (rank : 1478)	NC score	0.061215 (rank : 1003)
Query Neighborhood Hits	1024	Target Neighborhood Hits	164	Shared Neighborhood Hits	55
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SHE_MOUSE
θ value	θ > 10 (rank : 1479)	NC score	0.061949 (rank : 990)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SHLB2_HUMAN
θ value	θ > 10 (rank : 1480)	NC score	0.084790 (rank : 772)
Query Neighborhood Hits	1024	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	θ > 10 (rank : 1481)	NC score	0.085813 (rank : 765)
Query Neighborhood Hits	1024	Target Neighborhood Hits	88	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SLAP1_HUMAN
θ value	θ > 10 (rank : 1482)	NC score	0.144287 (rank : 508)
Query Neighborhood Hits	1024	Target Neighborhood Hits	113	Shared Neighborhood Hits	46
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 1483)	NC score	0.141880 (rank : 515)
Query Neighborhood Hits	1024	Target Neighborhood Hits	117	Shared Neighborhood Hits	45
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP2_MOUSE
θ value	θ > 10 (rank : 1484)	NC score	0.149956 (rank : 500)
Query Neighborhood Hits	1024	Target Neighborhood Hits	136	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SLY_HUMAN
θ value	θ > 10 (rank : 1485)	NC score	0.053218 (rank : 1199)
Query Neighborhood Hits	1024	Target Neighborhood Hits	81	Shared Neighborhood Hits	52
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SLY_MOUSE
θ value	θ > 10 (rank : 1486)	NC score	0.060299 (rank : 1016)
Query Neighborhood Hits	1024	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SMAP1_HUMAN
θ value	θ > 10 (rank : 1487)	NC score	0.051510 (rank : 1243)
Query Neighborhood Hits	1024	Target Neighborhood Hits	98	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 1488)	NC score	0.052862 (rank : 1208)
Query Neighborhood Hits	1024	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 1489)	NC score	0.050372 (rank : 1275)
Query Neighborhood Hits	1024	Target Neighborhood Hits	74	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMR3A_HUMAN
θ value	θ > 10 (rank : 1490)	NC score	0.065082 (rank : 951)
Query Neighborhood Hits	1024	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SNPC4_HUMAN
θ value	θ > 10 (rank : 1491)	NC score	0.141876 (rank : 516)
Query Neighborhood Hits	1024	Target Neighborhood Hits	589	Shared Neighborhood Hits	259
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SNX9_HUMAN
θ value	θ > 10 (rank : 1492)	NC score	0.081476 (rank : 793)
Query Neighborhood Hits	1024	Target Neighborhood Hits	148	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SNX9_MOUSE
θ value	θ > 10 (rank : 1493)	NC score	0.068872 (rank : 907)
Query Neighborhood Hits	1024	Target Neighborhood Hits	141	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

SOCS7_MOUSE
θ value	θ > 10 (rank : 1494)	NC score	0.050736 (rank : 1264)
Query Neighborhood Hits	1024	Target Neighborhood Hits	154	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SOX13_HUMAN
θ value	θ > 10 (rank : 1495)	NC score	0.058517 (rank : 1053)
Query Neighborhood Hits	1024	Target Neighborhood Hits	464	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SPN90_HUMAN
θ value	θ > 10 (rank : 1496)	NC score	0.120460 (rank : 590)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPN90_MOUSE
θ value	θ > 10 (rank : 1497)	NC score	0.108577 (rank : 650)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SPR1A_MOUSE
θ value	θ > 10 (rank : 1498)	NC score	0.089657 (rank : 742)
Query Neighborhood Hits	1024	Target Neighborhood Hits	343	Shared Neighborhood Hits	142
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SPR1B_MOUSE
θ value	θ > 10 (rank : 1499)	NC score	0.108818 (rank : 647)
Query Neighborhood Hits	1024	Target Neighborhood Hits	395	Shared Neighborhood Hits	162
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SPRR3_HUMAN
θ value	θ > 10 (rank : 1500)	NC score	0.052626 (rank : 1216)
Query Neighborhood Hits	1024	Target Neighborhood Hits	102	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SPTA1_HUMAN
θ value	θ > 10 (rank : 1501)	NC score	0.101239 (rank : 689)
Query Neighborhood Hits	1024	Target Neighborhood Hits	748	Shared Neighborhood Hits	175
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SRBP1_MOUSE
θ value	θ > 10 (rank : 1502)	NC score	0.080224 (rank : 807)
Query Neighborhood Hits	1024	Target Neighborhood Hits	384	Shared Neighborhood Hits	137
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRMS_HUMAN
θ value	θ > 10 (rank : 1503)	NC score	0.080368 (rank : 802)
Query Neighborhood Hits	1024	Target Neighborhood Hits	946	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 1504)	NC score	0.084373 (rank : 777)
Query Neighborhood Hits	1024	Target Neighborhood Hits	964	Shared Neighborhood Hits	136
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

STS1_HUMAN
θ value	θ > 10 (rank : 1505)	NC score	0.061212 (rank : 1004)
Query Neighborhood Hits	1024	Target Neighborhood Hits	106	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS1_MOUSE
θ value	θ > 10 (rank : 1506)	NC score	0.061704 (rank : 994)
Query Neighborhood Hits	1024	Target Neighborhood Hits	104	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STYK1_HUMAN
θ value	θ > 10 (rank : 1507)	NC score	0.055464 (rank : 1130)
Query Neighborhood Hits	1024	Target Neighborhood Hits	786	Shared Neighborhood Hits	71
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

STYK1_MOUSE
θ value	θ > 10 (rank : 1508)	NC score	0.054407 (rank : 1164)
Query Neighborhood Hits	1024	Target Neighborhood Hits	779	Shared Neighborhood Hits	73
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

SYNP2_HUMAN
θ value	θ > 10 (rank : 1509)	NC score	0.055365 (rank : 1134)
Query Neighborhood Hits	1024	Target Neighborhood Hits	323	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYNPO_MOUSE
θ value	θ > 10 (rank : 1510)	NC score	0.061775 (rank : 992)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	78
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TACC3_HUMAN
θ value	θ > 10 (rank : 1511)	NC score	0.050068 (rank : 1283)
Query Neighborhood Hits	1024	Target Neighborhood Hits	779	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TARA_HUMAN
θ value	θ > 10 (rank : 1512)	NC score	0.119737 (rank : 595)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1626	Shared Neighborhood Hits	326
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	θ > 10 (rank : 1513)	NC score	0.084617 (rank : 773)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1133	Shared Neighborhood Hits	212
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_MOUSE
θ value	θ > 10 (rank : 1514)	NC score	0.101499 (rank : 688)
Query Neighborhood Hits	1024	Target Neighborhood Hits	502	Shared Neighborhood Hits	184
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TB182_HUMAN
θ value	θ > 10 (rank : 1515)	NC score	0.079164 (rank : 816)
Query Neighborhood Hits	1024	Target Neighborhood Hits	414	Shared Neighborhood Hits	139
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCAL5_HUMAN
θ value	θ > 10 (rank : 1516)	NC score	0.056681 (rank : 1097)
Query Neighborhood Hits	1024	Target Neighborhood Hits	806	Shared Neighborhood Hits	127
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCOF_HUMAN
θ value	θ > 10 (rank : 1517)	NC score	0.063603 (rank : 969)
Query Neighborhood Hits	1024	Target Neighborhood Hits	543	Shared Neighborhood Hits	97
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 1518)	NC score	0.066254 (rank : 940)
Query Neighborhood Hits	1024	Target Neighborhood Hits	471	Shared Neighborhood Hits	100
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TGON2_HUMAN
θ value	θ > 10 (rank : 1519)	NC score	0.104616 (rank : 672)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1037	Shared Neighborhood Hits	222
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIAM1_HUMAN
θ value	θ > 10 (rank : 1520)	NC score	0.066448 (rank : 937)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	36
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 1521)	NC score	0.066971 (rank : 930)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIE1_HUMAN
θ value	θ > 10 (rank : 1522)	NC score	0.058255 (rank : 1060)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1241	Shared Neighborhood Hits	104
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 1523)	NC score	0.058042 (rank : 1063)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1266	Shared Neighborhood Hits	105
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 1524)	NC score	0.057314 (rank : 1081)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1192	Shared Neighborhood Hits	102
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 1525)	NC score	0.057028 (rank : 1088)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1204	Shared Neighborhood Hits	101
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TM108_MOUSE
θ value	θ > 10 (rank : 1526)	NC score	0.069683 (rank : 897)
Query Neighborhood Hits	1024	Target Neighborhood Hits	336	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 1527)	NC score	0.051337 (rank : 1247)
Query Neighborhood Hits	1024	Target Neighborhood Hits	140	Shared Neighborhood Hits	51
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TNK1_HUMAN
θ value	θ > 10 (rank : 1528)	NC score	0.059976 (rank : 1023)
Query Neighborhood Hits	1024	Target Neighborhood Hits	815	Shared Neighborhood Hits	93
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 1529)	NC score	0.058053 (rank : 1062)
Query Neighborhood Hits	1024	Target Neighborhood Hits	806	Shared Neighborhood Hits	86
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TP53B_MOUSE
θ value	θ > 10 (rank : 1530)	NC score	0.063082 (rank : 974)
Query Neighborhood Hits	1024	Target Neighborhood Hits	644	Shared Neighborhood Hits	147
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TPO_MOUSE
θ value	θ > 10 (rank : 1531)	NC score	0.070172 (rank : 891)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	119
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TROAP_HUMAN
θ value	θ > 10 (rank : 1532)	NC score	0.081086 (rank : 796)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	109
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TRPV1_HUMAN
θ value	θ > 10 (rank : 1533)	NC score	0.110621 (rank : 642)
Query Neighborhood Hits	1024	Target Neighborhood Hits	184	Shared Neighborhood Hits	135
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
θ value	θ > 10 (rank : 1534)	NC score	0.120139 (rank : 593)
Query Neighborhood Hits	1024	Target Neighborhood Hits	189	Shared Neighborhood Hits	142
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV2_HUMAN
θ value	θ > 10 (rank : 1535)	NC score	0.096245 (rank : 717)
Query Neighborhood Hits	1024	Target Neighborhood Hits	130	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 1536)	NC score	0.070113 (rank : 893)
Query Neighborhood Hits	1024	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV3_MOUSE
θ value	θ > 10 (rank : 1537)	NC score	0.110528 (rank : 643)
Query Neighborhood Hits	1024	Target Neighborhood Hits	188	Shared Neighborhood Hits	118
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	θ > 10 (rank : 1538)	NC score	0.052697 (rank : 1214)
Query Neighborhood Hits	1024	Target Neighborhood Hits	150	Shared Neighborhood Hits	83
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV5_HUMAN
θ value	θ > 10 (rank : 1539)	NC score	0.258881 (rank : 298)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
θ value	θ > 10 (rank : 1540)	NC score	0.247945 (rank : 314)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	210
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TS13_MOUSE
θ value	θ > 10 (rank : 1541)	NC score	0.076688 (rank : 831)
Query Neighborhood Hits	1024	Target Neighborhood Hits	191	Shared Neighborhood Hits	95
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

TULP4_HUMAN
θ value	θ > 10 (rank : 1542)	NC score	0.059163 (rank : 1038)
Query Neighborhood Hits	1024	Target Neighborhood Hits	426	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TXK_HUMAN
θ value	θ > 10 (rank : 1543)	NC score	0.090653 (rank : 740)
Query Neighborhood Hits	1024	Target Neighborhood Hits	971	Shared Neighborhood Hits	155
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1544)	NC score	0.094008 (rank : 728)
Query Neighborhood Hits	1024	Target Neighborhood Hits	980	Shared Neighborhood Hits	161
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TXLNA_HUMAN
θ value	θ > 10 (rank : 1545)	NC score	0.052152 (rank : 1228)
Query Neighborhood Hits	1024	Target Neighborhood Hits	982	Shared Neighborhood Hits	165
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXND2_HUMAN
θ value	θ > 10 (rank : 1546)	NC score	0.107758 (rank : 654)
Query Neighborhood Hits	1024	Target Neighborhood Hits	793	Shared Neighborhood Hits	171
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TYK2_MOUSE
θ value	θ > 10 (rank : 1547)	NC score	0.050056 (rank : 1286)
Query Neighborhood Hits	1024	Target Neighborhood Hits	850	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYRO3_HUMAN
θ value	θ > 10 (rank : 1548)	NC score	0.053396 (rank : 1192)
Query Neighborhood Hits	1024	Target Neighborhood Hits	995	Shared Neighborhood Hits	81
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	θ > 10 (rank : 1549)	NC score	0.053534 (rank : 1186)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1007	Shared Neighborhood Hits	84
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

UFO_HUMAN
θ value	θ > 10 (rank : 1550)	NC score	0.054617 (rank : 1158)
Query Neighborhood Hits	1024	Target Neighborhood Hits	981	Shared Neighborhood Hits	93
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 1551)	NC score	0.054173 (rank : 1171)
Query Neighborhood Hits	1024	Target Neighborhood Hits	988	Shared Neighborhood Hits	90
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

ULK1_MOUSE
θ value	θ > 10 (rank : 1552)	NC score	0.061374 (rank : 1001)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1214	Shared Neighborhood Hits	270
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

VAV3_HUMAN
θ value	θ > 10 (rank : 1553)	NC score	0.182038 (rank : 430)
Query Neighborhood Hits	1024	Target Neighborhood Hits	398	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VINEX_HUMAN
θ value	θ > 10 (rank : 1554)	NC score	0.238122 (rank : 336)
Query Neighborhood Hits	1024	Target Neighborhood Hits	270	Shared Neighborhood Hits	170
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

WASF1_HUMAN
θ value	θ > 10 (rank : 1555)	NC score	0.079388 (rank : 814)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	106
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 1556)	NC score	0.081513 (rank : 792)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	102
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF3_MOUSE
θ value	θ > 10 (rank : 1557)	NC score	0.062867 (rank : 980)
Query Neighborhood Hits	1024	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WBS14_HUMAN
θ value	θ > 10 (rank : 1558)	NC score	0.059610 (rank : 1029)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WNK2_HUMAN
θ value	θ > 10 (rank : 1559)	NC score	0.068047 (rank : 916)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1407	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZAP70_HUMAN
θ value	θ > 10 (rank : 1560)	NC score	0.064226 (rank : 962)
Query Neighborhood Hits	1024	Target Neighborhood Hits	893	Shared Neighborhood Hits	97
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 1561)	NC score	0.064653 (rank : 957)
Query Neighborhood Hits	1024	Target Neighborhood Hits	905	Shared Neighborhood Hits	97
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAR1_MOUSE
θ value	θ > 10 (rank : 1562)	NC score	0.071359 (rank : 878)
Query Neighborhood Hits	1024	Target Neighborhood Hits	254	Shared Neighborhood Hits	96
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZIMP7_HUMAN
θ value	θ > 10 (rank : 1563)	NC score	0.084037 (rank : 782)
Query Neighborhood Hits	1024	Target Neighborhood Hits	290	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIMP7_MOUSE
θ value	θ > 10 (rank : 1564)	NC score	0.162779 (rank : 471)
Query Neighborhood Hits	1024	Target Neighborhood Hits	566	Shared Neighborhood Hits	280
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN385_HUMAN
θ value	θ > 10 (rank : 1565)	NC score	0.175834 (rank : 438)
Query Neighborhood Hits	1024	Target Neighborhood Hits	614	Shared Neighborhood Hits	266
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZN645_HUMAN
θ value	θ > 10 (rank : 1566)	NC score	0.080563 (rank : 800)
Query Neighborhood Hits	1024	Target Neighborhood Hits	265	Shared Neighborhood Hits	98
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ZN750_MOUSE
θ value	θ > 10 (rank : 1567)	NC score	0.063481 (rank : 970)
Query Neighborhood Hits	1024	Target Neighborhood Hits	346	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

Hits sorted by NC score

IASPP_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1024	Shared Neighborhood Hits	1024
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IASPP_HUMAN
NC score	0.886219 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	1024	Target Neighborhood Hits	688	Shared Neighborhood Hits	548
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ASPP1_MOUSE
NC score	0.767951 (rank : 3)	θ value	1.65806e-78 (rank : 3)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1244	Shared Neighborhood Hits	567
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_HUMAN
NC score	0.756809 (rank : 4)	θ value	2.92676e-75 (rank : 4)
Query Neighborhood Hits	1024	Target Neighborhood Hits	956	Shared Neighborhood Hits	453
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
NC score	0.716428 (rank : 5)	θ value	2.3998e-69 (rank : 5)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1156	Shared Neighborhood Hits	481
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

PP16A_HUMAN
NC score	0.610104 (rank : 6)	θ value	1.68911e-14 (rank : 7)
Query Neighborhood Hits	1024	Target Neighborhood Hits	340	Shared Neighborhood Hits	270
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PP16B_HUMAN
NC score	0.608846 (rank : 7)	θ value	3.40345e-15 (rank : 6)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	256
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

PP16B_MOUSE
NC score	0.608026 (rank : 8)	θ value	1.68911e-14 (rank : 8)
Query Neighborhood Hits	1024	Target Neighborhood Hits	302	Shared Neighborhood Hits	254
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

PP16A_MOUSE
NC score	0.603124 (rank : 9)	θ value	8.38298e-14 (rank : 10)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	259
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

MYPT1_MOUSE
NC score	0.593761 (rank : 10)	θ value	1.09485e-13 (rank : 12)
Query Neighborhood Hits	1024	Target Neighborhood Hits	539	Shared Neighborhood Hits	276
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANR39_MOUSE
NC score	0.588596 (rank : 11)	θ value	4.59992e-12 (rank : 13)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	249
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_HUMAN
NC score	0.587926 (rank : 12)	θ value	6.00763e-12 (rank : 14)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	251
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR49_MOUSE
NC score	0.584591 (rank : 13)	θ value	6.21693e-09 (rank : 17)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	250
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR49_HUMAN
NC score	0.584259 (rank : 14)	θ value	8.11959e-09 (rank : 19)
Query Neighborhood Hits	1024	Target Neighborhood Hits	282	Shared Neighborhood Hits	251
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

MYPT2_HUMAN
NC score	0.584110 (rank : 15)	θ value	3.76295e-14 (rank : 9)
Query Neighborhood Hits	1024	Target Neighborhood Hits	707	Shared Neighborhood Hits	272
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

MYPT1_HUMAN
NC score	0.579548 (rank : 16)	θ value	1.09485e-13 (rank : 11)
Query Neighborhood Hits	1024	Target Neighborhood Hits	723	Shared Neighborhood Hits	279
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

OSTF1_MOUSE
NC score	0.578517 (rank : 17)	θ value	0.0961366 (rank : 451)
Query Neighborhood Hits	1024	Target Neighborhood Hits	467	Shared Neighborhood Hits	384
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

OSTF1_HUMAN
NC score	0.571625 (rank : 18)	θ value	0.0961366 (rank : 450)
Query Neighborhood Hits	1024	Target Neighborhood Hits	466	Shared Neighborhood Hits	382
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

PSD10_MOUSE
NC score	0.566375 (rank : 19)	θ value	4.0297e-08 (rank : 24)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MTPN_HUMAN
NC score	0.566373 (rank : 20)	θ value	1.87187e-05 (rank : 71)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	246
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

PSD10_HUMAN
NC score	0.565313 (rank : 21)	θ value	1.17247e-07 (rank : 32)
Query Neighborhood Hits	1024	Target Neighborhood Hits	301	Shared Neighborhood Hits	258
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MTPN_MOUSE
NC score	0.565260 (rank : 22)	θ value	1.09739e-05 (rank : 63)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	246
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANKR5_HUMAN
NC score	0.556484 (rank : 23)	θ value	1.99992e-07 (rank : 34)
Query Neighborhood Hits	1024	Target Neighborhood Hits	297	Shared Neighborhood Hits	253
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR5_MOUSE
NC score	0.556414 (rank : 24)	θ value	6.87365e-08 (rank : 28)
Query Neighborhood Hits	1024	Target Neighborhood Hits	298	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

TNKS1_HUMAN
NC score	0.553081 (rank : 25)	θ value	8.97725e-08 (rank : 30)
Query Neighborhood Hits	1024	Target Neighborhood Hits	477	Shared Neighborhood Hits	296
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANK2_HUMAN
NC score	0.553011 (rank : 26)	θ value	1.17247e-07 (rank : 31)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1615	Shared Neighborhood Hits	538
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR29_HUMAN
NC score	0.548550 (rank : 27)	θ value	2.61198e-07 (rank : 35)
Query Neighborhood Hits	1024	Target Neighborhood Hits	294	Shared Neighborhood Hits	254
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

TNKS2_HUMAN
NC score	0.546450 (rank : 28)	θ value	1.38499e-08 (rank : 21)
Query Neighborhood Hits	1024	Target Neighborhood Hits	361	Shared Neighborhood Hits	260
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR50_HUMAN
NC score	0.538972 (rank : 29)	θ value	4.45536e-07 (rank : 37)
Query Neighborhood Hits	1024	Target Neighborhood Hits	361	Shared Neighborhood Hits	260
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

CSKI1_MOUSE
NC score	0.538728 (rank : 30)	θ value	0.0330416 (rank : 364)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1031	Shared Neighborhood Hits	538
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_HUMAN
NC score	0.537621 (rank : 31)	θ value	7.1131e-05 (rank : 88)
Query Neighborhood Hits	1024	Target Neighborhood Hits	997	Shared Neighborhood Hits	512
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANR52_MOUSE
NC score	0.536675 (rank : 32)	θ value	3.64472e-09 (rank : 15)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR28_MOUSE
NC score	0.536523 (rank : 33)	θ value	6.87365e-08 (rank : 29)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	258
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR46_HUMAN
NC score	0.536219 (rank : 34)	θ value	0.00869519 (rank : 271)
Query Neighborhood Hits	1024	Target Neighborhood Hits	281	Shared Neighborhood Hits	248
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR44_HUMAN
NC score	0.535862 (rank : 35)	θ value	3.08544e-08 (rank : 22)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR52_HUMAN
NC score	0.535511 (rank : 36)	θ value	4.76016e-09 (rank : 16)
Query Neighborhood Hits	1024	Target Neighborhood Hits	322	Shared Neighborhood Hits	258
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

CSKI2_MOUSE
NC score	0.535119 (rank : 37)	θ value	0.000602161 (rank : 130)
Query Neighborhood Hits	1024	Target Neighborhood Hits	812	Shared Neighborhood Hits	452
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANK1_HUMAN
NC score	0.534826 (rank : 38)	θ value	6.87365e-08 (rank : 27)
Query Neighborhood Hits	1024	Target Neighborhood Hits	416	Shared Neighborhood Hits	264
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK3_HUMAN
NC score	0.534695 (rank : 39)	θ value	8.11959e-09 (rank : 18)
Query Neighborhood Hits	1024	Target Neighborhood Hits	853	Shared Neighborhood Hits	327
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR28_HUMAN
NC score	0.533547 (rank : 40)	θ value	7.59969e-07 (rank : 40)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	258
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANK1_MOUSE
NC score	0.533409 (rank : 41)	θ value	3.41135e-07 (rank : 36)
Query Neighborhood Hits	1024	Target Neighborhood Hits	430	Shared Neighborhood Hits	272
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANKR1_HUMAN
NC score	0.533050 (rank : 42)	θ value	1.09739e-05 (rank : 60)
Query Neighborhood Hits	1024	Target Neighborhood Hits	308	Shared Neighborhood Hits	255
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ACBD6_MOUSE
NC score	0.532569 (rank : 43)	θ value	0.00035302 (rank : 115)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	251
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKS3_MOUSE
NC score	0.532453 (rank : 44)	θ value	7.59969e-07 (rank : 39)
Query Neighborhood Hits	1024	Target Neighborhood Hits	355	Shared Neighborhood Hits	255
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR10_HUMAN
NC score	0.532295 (rank : 45)	θ value	3.77169e-06 (rank : 53)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANKS3_HUMAN
NC score	0.532076 (rank : 46)	θ value	4.92598e-06 (rank : 55)
Query Neighborhood Hits	1024	Target Neighborhood Hits	355	Shared Neighborhood Hits	255
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANKS6_MOUSE
NC score	0.531951 (rank : 47)	θ value	9.92553e-07 (rank : 44)
Query Neighborhood Hits	1024	Target Neighborhood Hits	435	Shared Neighborhood Hits	280
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR10_MOUSE
NC score	0.530813 (rank : 48)	θ value	1.29631e-06 (rank : 45)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	243
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANKR1_MOUSE
NC score	0.530597 (rank : 49)	θ value	1.43324e-05 (rank : 65)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	253
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

BARD1_MOUSE
NC score	0.528251 (rank : 50)	θ value	5.81887e-07 (rank : 38)
Query Neighborhood Hits	1024	Target Neighborhood Hits	411	Shared Neighborhood Hits	253
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANKR6_HUMAN
NC score	0.527306 (rank : 51)	θ value	0.000786445 (rank : 138)
Query Neighborhood Hits	1024	Target Neighborhood Hits	439	Shared Neighborhood Hits	278
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

EHMT2_MOUSE
NC score	0.527167 (rank : 52)	θ value	2.88788e-06 (rank : 51)
Query Neighborhood Hits	1024	Target Neighborhood Hits	750	Shared Neighborhood Hits	416
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

CSKI2_HUMAN
NC score	0.527061 (rank : 53)	θ value	0.000786445 (rank : 142)
Query Neighborhood Hits	1024	Target Neighborhood Hits	747	Shared Neighborhood Hits	401
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKS6_HUMAN
NC score	0.525928 (rank : 54)	θ value	6.43352e-06 (rank : 59)
Query Neighborhood Hits	1024	Target Neighborhood Hits	411	Shared Neighborhood Hits	281
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR46_MOUSE
NC score	0.525365 (rank : 55)	θ value	0.0252991 (rank : 341)
Query Neighborhood Hits	1024	Target Neighborhood Hits	274	Shared Neighborhood Hits	246
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

INVS_MOUSE
NC score	0.524066 (rank : 56)	θ value	0.00102713 (rank : 158)
Query Neighborhood Hits	1024	Target Neighborhood Hits	609	Shared Neighborhood Hits	359
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR16_HUMAN
NC score	0.523561 (rank : 57)	θ value	0.0563607 (rank : 400)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	253
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR23_HUMAN
NC score	0.523500 (rank : 58)	θ value	0.00390308 (rank : 223)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	255
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

BARD1_HUMAN
NC score	0.522693 (rank : 59)	θ value	5.44631e-05 (rank : 85)
Query Neighborhood Hits	1024	Target Neighborhood Hits	427	Shared Neighborhood Hits	258
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANR23_MOUSE
NC score	0.522617 (rank : 60)	θ value	0.0252991 (rank : 340)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	256
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANKR2_MOUSE
NC score	0.522351 (rank : 61)	θ value	0.00390308 (rank : 222)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	256
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

GABP3_MOUSE
NC score	0.521870 (rank : 62)	θ value	0.00509761 (rank : 238)
Query Neighborhood Hits	1024	Target Neighborhood Hits	330	Shared Neighborhood Hits	252
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ACBD6_HUMAN
NC score	0.521671 (rank : 63)	θ value	0.000158464 (rank : 97)
Query Neighborhood Hits	1024	Target Neighborhood Hits	304	Shared Neighborhood Hits	250
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKR2_HUMAN
NC score	0.520304 (rank : 64)	θ value	0.00869519 (rank : 270)
Query Neighborhood Hits	1024	Target Neighborhood Hits	321	Shared Neighborhood Hits	256
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

CT086_HUMAN
NC score	0.520228 (rank : 65)	θ value	0.0563607 (rank : 410)
Query Neighborhood Hits	1024	Target Neighborhood Hits	277	Shared Neighborhood Hits	247
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

INVS_HUMAN
NC score	0.519791 (rank : 66)	θ value	0.00102713 (rank : 157)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	302
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ASB2_HUMAN
NC score	0.518452 (rank : 67)	θ value	2.44474e-05 (rank : 74)
Query Neighborhood Hits	1024	Target Neighborhood Hits	309	Shared Neighborhood Hits	256
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR42_MOUSE
NC score	0.518206 (rank : 68)	θ value	0.0148317 (rank : 298)
Query Neighborhood Hits	1024	Target Neighborhood Hits	334	Shared Neighborhood Hits	253
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

CDN2C_MOUSE
NC score	0.516885 (rank : 69)	θ value	0.0330416 (rank : 361)
Query Neighborhood Hits	1024	Target Neighborhood Hits	270	Shared Neighborhood Hits	243
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANR42_HUMAN
NC score	0.515853 (rank : 70)	θ value	0.365318 (rank : 551)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB3_MOUSE
NC score	0.515521 (rank : 71)	θ value	0.0113563 (rank : 287)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

CDN2D_HUMAN
NC score	0.515036 (rank : 72)	θ value	0.000786445 (rank : 140)
Query Neighborhood Hits	1024	Target Neighborhood Hits	268	Shared Neighborhood Hits	242
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CDN2C_HUMAN
NC score	0.514344 (rank : 73)	θ value	0.21417 (rank : 502)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	240
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ASB2_MOUSE
NC score	0.514311 (rank : 74)	θ value	0.000121331 (rank : 96)
Query Neighborhood Hits	1024	Target Neighborhood Hits	321	Shared Neighborhood Hits	258
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

SHAN1_HUMAN
NC score	0.514294 (rank : 75)	θ value	0.0113563 (rank : 295)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1041	Shared Neighborhood Hits	500
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ASB3_HUMAN
NC score	0.513654 (rank : 76)	θ value	0.00869519 (rank : 274)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

GABP2_HUMAN
NC score	0.513374 (rank : 77)	θ value	0.00869519 (rank : 277)
Query Neighborhood Hits	1024	Target Neighborhood Hits	454	Shared Neighborhood Hits	266
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ASB10_MOUSE
NC score	0.513000 (rank : 78)	θ value	0.00665767 (rank : 255)
Query Neighborhood Hits	1024	Target Neighborhood Hits	301	Shared Neighborhood Hits	254
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB13_HUMAN
NC score	0.512848 (rank : 79)	θ value	0.00102713 (rank : 152)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
NC score	0.512396 (rank : 80)	θ value	0.00134147 (rank : 166)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	253
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

GABP2_MOUSE
NC score	0.512192 (rank : 81)	θ value	0.0563607 (rank : 411)
Query Neighborhood Hits	1024	Target Neighborhood Hits	429	Shared Neighborhood Hits	265
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

BCL3_HUMAN
NC score	0.511872 (rank : 82)	θ value	0.00134147 (rank : 168)
Query Neighborhood Hits	1024	Target Neighborhood Hits	324	Shared Neighborhood Hits	267
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ASB10_HUMAN
NC score	0.511606 (rank : 83)	θ value	0.0736092 (rank : 424)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	252
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

FANK1_HUMAN
NC score	0.510234 (rank : 84)	θ value	0.279714 (rank : 531)
Query Neighborhood Hits	1024	Target Neighborhood Hits	326	Shared Neighborhood Hits	257
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

PA2G6_MOUSE
NC score	0.509593 (rank : 85)	θ value	0.00020696 (rank : 101)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	253
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

USH1G_MOUSE
NC score	0.508764 (rank : 86)	θ value	0.00035302 (rank : 124)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	246
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ASZ1_MOUSE
NC score	0.508738 (rank : 87)	θ value	0.00665767 (rank : 256)
Query Neighborhood Hits	1024	Target Neighborhood Hits	319	Shared Neighborhood Hits	248
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

USH1G_HUMAN
NC score	0.508709 (rank : 88)	θ value	0.00035302 (rank : 123)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	245
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

CDN2D_MOUSE
NC score	0.508646 (rank : 89)	θ value	0.00298849 (rank : 206)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	242
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

FANK1_MOUSE
NC score	0.508374 (rank : 90)	θ value	1.06291 (rank : 677)
Query Neighborhood Hits	1024	Target Neighborhood Hits	325	Shared Neighborhood Hits	258
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

BCL3_MOUSE
NC score	0.507711 (rank : 91)	θ value	0.0193708 (rank : 323)
Query Neighborhood Hits	1024	Target Neighborhood Hits	388	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANR11_HUMAN
NC score	0.506423 (rank : 92)	θ value	4.1701e-05 (rank : 80)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1289	Shared Neighborhood Hits	424
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

TRPA1_MOUSE
NC score	0.505998 (rank : 93)	θ value	0.00298849 (rank : 220)
Query Neighborhood Hits	1024	Target Neighborhood Hits	343	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ASB8_HUMAN
NC score	0.505631 (rank : 94)	θ value	0.0148317 (rank : 300)
Query Neighborhood Hits	1024	Target Neighborhood Hits	294	Shared Neighborhood Hits	252
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
NC score	0.505538 (rank : 95)	θ value	0.0148317 (rank : 301)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

IKBE_MOUSE
NC score	0.504156 (rank : 96)	θ value	0.00102713 (rank : 156)
Query Neighborhood Hits	1024	Target Neighborhood Hits	308	Shared Neighborhood Hits	252
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANRA2_MOUSE
NC score	0.502351 (rank : 97)	θ value	0.0961366 (rank : 444)
Query Neighborhood Hits	1024	Target Neighborhood Hits	287	Shared Neighborhood Hits	249
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANS4B_HUMAN
NC score	0.502299 (rank : 98)	θ value	0.00869519 (rank : 272)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	245
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

EHMT2_HUMAN
NC score	0.502162 (rank : 99)	θ value	7.59969e-07 (rank : 42)
Query Neighborhood Hits	1024	Target Neighborhood Hits	498	Shared Neighborhood Hits	283
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB15_HUMAN
NC score	0.502118 (rank : 100)	θ value	0.00020696 (rank : 99)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	255
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB16_MOUSE
NC score	0.501906 (rank : 101)	θ value	0.0563607 (rank : 403)
Query Neighborhood Hits	1024	Target Neighborhood Hits	306	Shared Neighborhood Hits	253
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

RFXK_HUMAN
NC score	0.501708 (rank : 102)	θ value	0.00665767 (rank : 267)
Query Neighborhood Hits	1024	Target Neighborhood Hits	282	Shared Neighborhood Hits	246
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANRA2_HUMAN
NC score	0.501587 (rank : 103)	θ value	0.163984 (rank : 478)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	250
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANKR7_HUMAN
NC score	0.500830 (rank : 104)	θ value	0.000270298 (rank : 103)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	252
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

EHMT1_HUMAN
NC score	0.500823 (rank : 105)	θ value	0.00390308 (rank : 225)
Query Neighborhood Hits	1024	Target Neighborhood Hits	417	Shared Neighborhood Hits	274
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

TRPA1_HUMAN
NC score	0.500648 (rank : 106)	θ value	0.00665767 (rank : 268)
Query Neighborhood Hits	1024	Target Neighborhood Hits	339	Shared Neighborhood Hits	258
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

PA2G6_HUMAN
NC score	0.500559 (rank : 107)	θ value	0.00134147 (rank : 174)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANS4B_MOUSE
NC score	0.499917 (rank : 108)	θ value	0.00298849 (rank : 204)
Query Neighborhood Hits	1024	Target Neighborhood Hits	294	Shared Neighborhood Hits	241
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR32_HUMAN
NC score	0.498731 (rank : 109)	θ value	0.000602161 (rank : 129)
Query Neighborhood Hits	1024	Target Neighborhood Hits	270	Shared Neighborhood Hits	237
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

BCOR_HUMAN
NC score	0.498536 (rank : 110)	θ value	0.000270298 (rank : 105)
Query Neighborhood Hits	1024	Target Neighborhood Hits	609	Shared Neighborhood Hits	340
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ASB7_MOUSE
NC score	0.496053 (rank : 111)	θ value	0.813845 (rank : 632)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	254
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.495832 (rank : 112)	θ value	0.813845 (rank : 631)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	254
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB16_HUMAN
NC score	0.495507 (rank : 113)	θ value	0.0113563 (rank : 286)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	251
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB5_HUMAN
NC score	0.493681 (rank : 114)	θ value	0.0113563 (rank : 288)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	246
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB15_MOUSE
NC score	0.493411 (rank : 115)	θ value	0.00134147 (rank : 167)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	250
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

IKBE_HUMAN
NC score	0.492663 (rank : 116)	θ value	0.00228821 (rank : 194)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	249
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

RN5A_HUMAN
NC score	0.492467 (rank : 117)	θ value	0.00175202 (rank : 187)
Query Neighborhood Hits	1024	Target Neighborhood Hits	608	Shared Neighborhood Hits	282
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASZ1_HUMAN
NC score	0.491745 (rank : 118)	θ value	0.0563607 (rank : 404)
Query Neighborhood Hits	1024	Target Neighborhood Hits	341	Shared Neighborhood Hits	248
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB9_HUMAN
NC score	0.491645 (rank : 119)	θ value	0.0330416 (rank : 359)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	240
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

RFXK_MOUSE
NC score	0.490525 (rank : 120)	θ value	0.813845 (rank : 656)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	247
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ANKS1_HUMAN
NC score	0.490097 (rank : 121)	θ value	0.00665767 (rank : 252)
Query Neighborhood Hits	1024	Target Neighborhood Hits	438	Shared Neighborhood Hits	265
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

MIB1_MOUSE
NC score	0.490046 (rank : 122)	θ value	0.00665767 (rank : 264)
Query Neighborhood Hits	1024	Target Neighborhood Hits	471	Shared Neighborhood Hits	260
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB1_HUMAN
NC score	0.489908 (rank : 123)	θ value	0.00665767 (rank : 263)
Query Neighborhood Hits	1024	Target Neighborhood Hits	470	Shared Neighborhood Hits	260
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

ANR32_MOUSE
NC score	0.489898 (rank : 124)	θ value	0.00298849 (rank : 202)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	237
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ASB5_MOUSE
NC score	0.489165 (rank : 125)	θ value	0.0252991 (rank : 343)
Query Neighborhood Hits	1024	Target Neighborhood Hits	266	Shared Neighborhood Hits	240
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANKS1_MOUSE
NC score	0.487522 (rank : 126)	θ value	0.00228821 (rank : 191)
Query Neighborhood Hits	1024	Target Neighborhood Hits	453	Shared Neighborhood Hits	274
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ASB11_MOUSE
NC score	0.485144 (rank : 127)	θ value	0.0193708 (rank : 320)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB14_MOUSE
NC score	0.484982 (rank : 128)	θ value	0.0193708 (rank : 321)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	249
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB11_HUMAN
NC score	0.484253 (rank : 129)	θ value	0.0330416 (rank : 357)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

BCOR_MOUSE
NC score	0.480669 (rank : 130)	θ value	0.00298849 (rank : 205)
Query Neighborhood Hits	1024	Target Neighborhood Hits	521	Shared Neighborhood Hits	304
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ASB9_MOUSE
NC score	0.480171 (rank : 131)	θ value	0.0736092 (rank : 425)
Query Neighborhood Hits	1024	Target Neighborhood Hits	257	Shared Neighborhood Hits	232
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MIB2_HUMAN
NC score	0.479737 (rank : 132)	θ value	0.0148317 (rank : 313)
Query Neighborhood Hits	1024	Target Neighborhood Hits	438	Shared Neighborhood Hits	260
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
NC score	0.478916 (rank : 133)	θ value	0.0252991 (rank : 348)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	257
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

IKBA_HUMAN
NC score	0.474935 (rank : 134)	θ value	0.279714 (rank : 536)
Query Neighborhood Hits	1024	Target Neighborhood Hits	280	Shared Neighborhood Hits	249
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

IKBB_MOUSE
NC score	0.473466 (rank : 135)	θ value	0.0431538 (rank : 386)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	246
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ASB1_HUMAN
NC score	0.472691 (rank : 136)	θ value	0.0330416 (rank : 358)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR35_HUMAN
NC score	0.472359 (rank : 137)	θ value	4.1701e-05 (rank : 81)
Query Neighborhood Hits	1024	Target Neighborhood Hits	784	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ANR12_HUMAN
NC score	0.471421 (rank : 138)	θ value	1.09739e-05 (rank : 61)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1081	Shared Neighborhood Hits	298
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR45_MOUSE
NC score	0.469693 (rank : 139)	θ value	0.00665767 (rank : 254)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	183
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASB1_MOUSE
NC score	0.469404 (rank : 140)	θ value	0.0193708 (rank : 322)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	247
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

IKBB_HUMAN
NC score	0.469300 (rank : 141)	θ value	0.0563607 (rank : 412)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	252
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBA_MOUSE
NC score	0.468315 (rank : 142)	θ value	0.21417 (rank : 509)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANFY1_HUMAN
NC score	0.466771 (rank : 143)	θ value	0.000786445 (rank : 137)
Query Neighborhood Hits	1024	Target Neighborhood Hits	480	Shared Neighborhood Hits	261
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
NC score	0.466483 (rank : 144)	θ value	0.00102713 (rank : 151)
Query Neighborhood Hits	1024	Target Neighborhood Hits	480	Shared Neighborhood Hits	261
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

AN36B_HUMAN
NC score	0.465691 (rank : 145)	θ value	0.279714 (rank : 521)
Query Neighborhood Hits	1024	Target Neighborhood Hits	294	Shared Neighborhood Hits	252
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

RN5A_MOUSE
NC score	0.464158 (rank : 146)	θ value	0.0330416 (rank : 374)
Query Neighborhood Hits	1024	Target Neighborhood Hits	899	Shared Neighborhood Hits	304
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB4_HUMAN
NC score	0.463929 (rank : 147)	θ value	0.813845 (rank : 630)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	245
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CTTB2_HUMAN
NC score	0.463190 (rank : 148)	θ value	0.00298849 (rank : 210)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1061	Shared Neighborhood Hits	331
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR37_MOUSE
NC score	0.462628 (rank : 149)	θ value	0.21417 (rank : 499)
Query Neighborhood Hits	1024	Target Neighborhood Hits	237	Shared Neighborhood Hits	221
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ZDH17_HUMAN
NC score	0.460803 (rank : 150)	θ value	0.000602161 (rank : 135)
Query Neighborhood Hits	1024	Target Neighborhood Hits	334	Shared Neighborhood Hits	254
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANR15_HUMAN
NC score	0.460175 (rank : 151)	θ value	0.00298849 (rank : 201)
Query Neighborhood Hits	1024	Target Neighborhood Hits	478	Shared Neighborhood Hits	266
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ZDH17_MOUSE
NC score	0.459112 (rank : 152)	θ value	0.000602161 (rank : 136)
Query Neighborhood Hits	1024	Target Neighborhood Hits	328	Shared Neighborhood Hits	254
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ZDH13_HUMAN
NC score	0.458769 (rank : 153)	θ value	0.00102713 (rank : 164)
Query Neighborhood Hits	1024	Target Neighborhood Hits	322	Shared Neighborhood Hits	252
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

POTE8_HUMAN
NC score	0.458134 (rank : 154)	θ value	0.00228821 (rank : 197)
Query Neighborhood Hits	1024	Target Neighborhood Hits	337	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ASB4_MOUSE
NC score	0.457703 (rank : 155)	θ value	8.99809 (rank : 975)
Query Neighborhood Hits	1024	Target Neighborhood Hits	265	Shared Neighborhood Hits	245
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ZDH13_MOUSE
NC score	0.457656 (rank : 156)	θ value	0.00102713 (rank : 165)
Query Neighborhood Hits	1024	Target Neighborhood Hits	329	Shared Neighborhood Hits	254
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANR22_HUMAN
NC score	0.456873 (rank : 157)	θ value	6.88961 (rank : 924)
Query Neighborhood Hits	1024	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR41_HUMAN
NC score	0.455208 (rank : 158)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	1024	Target Neighborhood Hits	332	Shared Neighborhood Hits	277
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

NFKB1_MOUSE
NC score	0.454715 (rank : 159)	θ value	2.21117e-06 (rank : 49)
Query Neighborhood Hits	1024	Target Neighborhood Hits	300	Shared Neighborhood Hits	253
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANR19_HUMAN
NC score	0.453064 (rank : 160)	θ value	0.00665767 (rank : 253)
Query Neighborhood Hits	1024	Target Neighborhood Hits	276	Shared Neighborhood Hits	246
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

AN36A_HUMAN
NC score	0.452352 (rank : 161)	θ value	0.0736092 (rank : 423)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	248
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR37_HUMAN
NC score	0.451225 (rank : 162)	θ value	3.0926 (rank : 802)
Query Neighborhood Hits	1024	Target Neighborhood Hits	247	Shared Neighborhood Hits	232
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ASB12_HUMAN
NC score	0.450494 (rank : 163)	θ value	8.99809 (rank : 974)
Query Neighborhood Hits	1024	Target Neighborhood Hits	263	Shared Neighborhood Hits	243
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB12_MOUSE
NC score	0.450429 (rank : 164)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	242
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANR45_HUMAN
NC score	0.449428 (rank : 165)	θ value	0.00298849 (rank : 203)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	178
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

SNCAP_HUMAN
NC score	0.448023 (rank : 166)	θ value	0.813845 (rank : 659)
Query Neighborhood Hits	1024	Target Neighborhood Hits	313	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANR47_MOUSE
NC score	0.444223 (rank : 167)	θ value	0.813845 (rank : 629)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	256
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

NFKB1_HUMAN
NC score	0.443038 (rank : 168)	θ value	7.1131e-05 (rank : 89)
Query Neighborhood Hits	1024	Target Neighborhood Hits	306	Shared Neighborhood Hits	254
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANR47_HUMAN
NC score	0.441565 (rank : 169)	θ value	0.0148317 (rank : 299)
Query Neighborhood Hits	1024	Target Neighborhood Hits	369	Shared Neighborhood Hits	264
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

NFKB2_HUMAN
NC score	0.437681 (rank : 170)	θ value	0.000786445 (rank : 145)
Query Neighborhood Hits	1024	Target Neighborhood Hits	325	Shared Neighborhood Hits	255
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR25_HUMAN
NC score	0.435445 (rank : 171)	θ value	0.00035302 (rank : 116)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANKY2_HUMAN
NC score	0.433829 (rank : 172)	θ value	1.06291 (rank : 666)
Query Neighborhood Hits	1024	Target Neighborhood Hits	306	Shared Neighborhood Hits	238
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR25_MOUSE
NC score	0.432232 (rank : 173)	θ value	0.000786445 (rank : 139)
Query Neighborhood Hits	1024	Target Neighborhood Hits	398	Shared Neighborhood Hits	281
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

POT15_HUMAN
NC score	0.428084 (rank : 174)	θ value	0.0252991 (rank : 351)
Query Neighborhood Hits	1024	Target Neighborhood Hits	893	Shared Neighborhood Hits	289
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

NFKB2_MOUSE
NC score	0.427591 (rank : 175)	θ value	0.0193708 (rank : 333)
Query Neighborhood Hits	1024	Target Neighborhood Hits	326	Shared Neighborhood Hits	257
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR21_HUMAN
NC score	0.427439 (rank : 176)	θ value	0.0563607 (rank : 401)
Query Neighborhood Hits	1024	Target Neighborhood Hits	864	Shared Neighborhood Hits	285
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT14_HUMAN
NC score	0.423266 (rank : 177)	θ value	0.0431538 (rank : 391)
Query Neighborhood Hits	1024	Target Neighborhood Hits	403	Shared Neighborhood Hits	260
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANKY2_MOUSE
NC score	0.421117 (rank : 178)	θ value	1.81305 (rank : 736)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	237
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ASB6_HUMAN
NC score	0.418698 (rank : 179)	θ value	3.0926 (rank : 803)
Query Neighborhood Hits	1024	Target Neighborhood Hits	256	Shared Neighborhood Hits	223
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

KRIT1_MOUSE
NC score	0.418631 (rank : 180)	θ value	5.27518 (rank : 902)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	219
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

ASB6_MOUSE
NC score	0.412870 (rank : 181)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	224
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CLPB_MOUSE
NC score	0.410493 (rank : 182)	θ value	1.38821 (rank : 707)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	238
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

KRIT1_HUMAN
NC score	0.405493 (rank : 183)	θ value	8.99809 (rank : 996)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	214
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

CD2A1_MOUSE
NC score	0.403256 (rank : 184)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	191
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

OSBL1_HUMAN
NC score	0.401845 (rank : 185)	θ value	0.365318 (rank : 564)
Query Neighborhood Hits	1024	Target Neighborhood Hits	368	Shared Neighborhood Hits	260
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

A20A3_HUMAN
NC score	0.396203 (rank : 186)	θ value	0.0193708 (rank : 317)
Query Neighborhood Hits	1024	Target Neighborhood Hits	692	Shared Neighborhood Hits	264
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A1_HUMAN
NC score	0.394787 (rank : 187)	θ value	0.0252991 (rank : 339)
Query Neighborhood Hits	1024	Target Neighborhood Hits	698	Shared Neighborhood Hits	261
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A4_HUMAN
NC score	0.393466 (rank : 188)	θ value	0.0193708 (rank : 318)
Query Neighborhood Hits	1024	Target Neighborhood Hits	710	Shared Neighborhood Hits	265
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

A20A2_HUMAN
NC score	0.392635 (rank : 189)	θ value	0.0563607 (rank : 396)
Query Neighborhood Hits	1024	Target Neighborhood Hits	716	Shared Neighborhood Hits	259
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

OSBL1_MOUSE
NC score	0.392330 (rank : 190)	θ value	0.365318 (rank : 565)
Query Neighborhood Hits	1024	Target Neighborhood Hits	336	Shared Neighborhood Hits	248
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

POT22_HUMAN
NC score	0.391330 (rank : 191)	θ value	1.81305 (rank : 750)
Query Neighborhood Hits	1024	Target Neighborhood Hits	266	Shared Neighborhood Hits	241
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

MPP8_HUMAN
NC score	0.389340 (rank : 192)	θ value	3.0926 (rank : 824)
Query Neighborhood Hits	1024	Target Neighborhood Hits	948	Shared Neighborhood Hits	286
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR38_HUMAN
NC score	0.386088 (rank : 193)	θ value	0.62314 (rank : 604)
Query Neighborhood Hits	1024	Target Neighborhood Hits	443	Shared Neighborhood Hits	247
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANKK1_HUMAN
NC score	0.377776 (rank : 194)	θ value	3.77169e-06 (rank : 52)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1075	Shared Neighborhood Hits	318
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANR38_MOUSE
NC score	0.377251 (rank : 195)	θ value	0.47712 (rank : 575)
Query Neighborhood Hits	1024	Target Neighborhood Hits	512	Shared Neighborhood Hits	253
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CENB5_HUMAN
NC score	0.376759 (rank : 196)	θ value	0.00298849 (rank : 207)
Query Neighborhood Hits	1024	Target Neighborhood Hits	395	Shared Neighborhood Hits	254
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB1_HUMAN
NC score	0.376522 (rank : 197)	θ value	0.0563607 (rank : 406)
Query Neighborhood Hits	1024	Target Neighborhood Hits	383	Shared Neighborhood Hits	254
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
NC score	0.374196 (rank : 198)	θ value	0.00228821 (rank : 192)
Query Neighborhood Hits	1024	Target Neighborhood Hits	425	Shared Neighborhood Hits	249
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ILK2_HUMAN
NC score	0.373715 (rank : 199)	θ value	0.00390308 (rank : 228)
Query Neighborhood Hits	1024	Target Neighborhood Hits	848	Shared Neighborhood Hits	296
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

CDN2B_MOUSE
NC score	0.371066 (rank : 200)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	186
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

RAI14_HUMAN
NC score	0.370763 (rank : 201)	θ value	0.813845 (rank : 655)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1367	Shared Neighborhood Hits	316
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ANR33_MOUSE
NC score	0.370372 (rank : 202)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	215
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

BCAR1_HUMAN
NC score	0.370331 (rank : 203)	θ value	1.53129e-07 (rank : 33)
Query Neighborhood Hits	1024	Target Neighborhood Hits	554	Shared Neighborhood Hits	324
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

GLSL_HUMAN
NC score	0.369809 (rank : 204)	θ value	0.00509761 (rank : 239)
Query Neighborhood Hits	1024	Target Neighborhood Hits	211	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ANKK1_MOUSE
NC score	0.368181 (rank : 205)	θ value	7.1131e-05 (rank : 87)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1072	Shared Neighborhood Hits	316
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ABTB2_HUMAN
NC score	0.367377 (rank : 206)	θ value	0.0563607 (rank : 397)
Query Neighborhood Hits	1024	Target Neighborhood Hits	391	Shared Neighborhood Hits	222
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

RIPK4_HUMAN
NC score	0.365830 (rank : 207)	θ value	0.00175202 (rank : 186)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1094	Shared Neighborhood Hits	323
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANR33_HUMAN
NC score	0.364413 (rank : 208)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	1024	Target Neighborhood Hits	215	Shared Neighborhood Hits	205
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ILK1_HUMAN
NC score	0.362845 (rank : 209)	θ value	0.00390308 (rank : 227)
Query Neighborhood Hits	1024	Target Neighborhood Hits	857	Shared Neighborhood Hits	296
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

GLSL_MOUSE
NC score	0.361492 (rank : 210)	θ value	0.00665767 (rank : 262)
Query Neighborhood Hits	1024	Target Neighborhood Hits	212	Shared Neighborhood Hits	187
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

BCAR1_MOUSE
NC score	0.361344 (rank : 211)	θ value	5.26297e-08 (rank : 25)
Query Neighborhood Hits	1024	Target Neighborhood Hits	438	Shared Neighborhood Hits	276
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

DDEF2_HUMAN
NC score	0.361051 (rank : 212)	θ value	0.0736092 (rank : 429)
Query Neighborhood Hits	1024	Target Neighborhood Hits	599	Shared Neighborhood Hits	379
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ILK_MOUSE
NC score	0.360303 (rank : 213)	θ value	0.00869519 (rank : 278)
Query Neighborhood Hits	1024	Target Neighborhood Hits	858	Shared Neighborhood Hits	300
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

RAI14_MOUSE
NC score	0.357972 (rank : 214)	θ value	0.47712 (rank : 594)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1505	Shared Neighborhood Hits	327
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ABTB2_MOUSE
NC score	0.356796 (rank : 215)	θ value	0.0431538 (rank : 377)
Query Neighborhood Hits	1024	Target Neighborhood Hits	414	Shared Neighborhood Hits	220
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

DDEF2_MOUSE
NC score	0.356378 (rank : 216)	θ value	0.163984 (rank : 481)
Query Neighborhood Hits	1024	Target Neighborhood Hits	625	Shared Neighborhood Hits	384
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CD2A1_HUMAN
NC score	0.354686 (rank : 217)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	1024	Target Neighborhood Hits	196	Shared Neighborhood Hits	182
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ANR40_HUMAN
NC score	0.353174 (rank : 218)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	1024	Target Neighborhood Hits	224	Shared Neighborhood Hits	200
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
NC score	0.352847 (rank : 219)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	202
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR18_HUMAN
NC score	0.352413 (rank : 220)	θ value	0.62314 (rank : 603)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1106	Shared Neighborhood Hits	285
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

HECD1_HUMAN
NC score	0.352336 (rank : 221)	θ value	θ > 10 (rank : 1259)
Query Neighborhood Hits	1024	Target Neighborhood Hits	371	Shared Neighborhood Hits	249
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

AN30A_HUMAN
NC score	0.351906 (rank : 222)	θ value	0.62314 (rank : 602)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1119	Shared Neighborhood Hits	300
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR43_MOUSE
NC score	0.349934 (rank : 223)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	1024	Target Neighborhood Hits	214	Shared Neighborhood Hits	198
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_HUMAN
NC score	0.348265 (rank : 224)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	1024	Target Neighborhood Hits	209	Shared Neighborhood Hits	195
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CDN2B_HUMAN
NC score	0.346508 (rank : 225)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	1024	Target Neighborhood Hits	196	Shared Neighborhood Hits	181
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CLPB_HUMAN
NC score	0.345621 (rank : 226)	θ value	0.813845 (rank : 636)
Query Neighborhood Hits	1024	Target Neighborhood Hits	265	Shared Neighborhood Hits	212
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

EFS_MOUSE
NC score	0.343998 (rank : 227)	θ value	1.69304e-06 (rank : 47)
Query Neighborhood Hits	1024	Target Neighborhood Hits	389	Shared Neighborhood Hits	234
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

DDFL1_MOUSE
NC score	0.337332 (rank : 228)	θ value	0.00298849 (rank : 211)
Query Neighborhood Hits	1024	Target Neighborhood Hits	324	Shared Neighborhood Hits	242
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

AN13C_HUMAN
NC score	0.334400 (rank : 229)	θ value	0.0563607 (rank : 398)
Query Neighborhood Hits	1024	Target Neighborhood Hits	241	Shared Neighborhood Hits	223
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

CT032_HUMAN
NC score	0.327799 (rank : 230)	θ value	3.77169e-06 (rank : 54)
Query Neighborhood Hits	1024	Target Neighborhood Hits	235	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

AN13C_MOUSE
NC score	0.327248 (rank : 231)	θ value	0.0563607 (rank : 399)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	220
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13B_MOUSE
NC score	0.326412 (rank : 232)	θ value	3.0926 (rank : 800)
Query Neighborhood Hits	1024	Target Neighborhood Hits	276	Shared Neighborhood Hits	238
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

EFS_HUMAN
NC score	0.326306 (rank : 233)	θ value	1.69304e-06 (rank : 46)
Query Neighborhood Hits	1024	Target Neighborhood Hits	348	Shared Neighborhood Hits	210
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

AN13B_HUMAN
NC score	0.326114 (rank : 234)	θ value	3.0926 (rank : 799)
Query Neighborhood Hits	1024	Target Neighborhood Hits	265	Shared Neighborhood Hits	236
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

MUC1_HUMAN
NC score	0.322273 (rank : 235)	θ value	5.26297e-08 (rank : 26)
Query Neighborhood Hits	1024	Target Neighborhood Hits	975	Shared Neighborhood Hits	369
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

OGFR_HUMAN
NC score	0.321171 (rank : 236)	θ value	0.00228821 (rank : 196)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1582	Shared Neighborhood Hits	504
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SH3K1_HUMAN
NC score	0.320518 (rank : 237)	θ value	0.000786445 (rank : 147)
Query Neighborhood Hits	1024	Target Neighborhood Hits	341	Shared Neighborhood Hits	181
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
NC score	0.319889 (rank : 238)	θ value	0.000786445 (rank : 148)
Query Neighborhood Hits	1024	Target Neighborhood Hits	332	Shared Neighborhood Hits	179
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

GRAP2_MOUSE
NC score	0.318572 (rank : 239)	θ value	0.00035302 (rank : 118)
Query Neighborhood Hits	1024	Target Neighborhood Hits	297	Shared Neighborhood Hits	171
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP2_HUMAN
NC score	0.318163 (rank : 240)	θ value	0.000786445 (rank : 143)
Query Neighborhood Hits	1024	Target Neighborhood Hits	304	Shared Neighborhood Hits	173
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

ANKY1_HUMAN
NC score	0.317781 (rank : 241)	θ value	3.0926 (rank : 801)
Query Neighborhood Hits	1024	Target Neighborhood Hits	248	Shared Neighborhood Hits	194
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

TRPV6_MOUSE
NC score	0.316520 (rank : 242)	θ value	0.0736092 (rank : 441)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	234
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

CD2AP_MOUSE
NC score	0.315439 (rank : 243)	θ value	0.00175202 (rank : 179)
Query Neighborhood Hits	1024	Target Neighborhood Hits	336	Shared Neighborhood Hits	188
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

GRB2_HUMAN
NC score	0.315074 (rank : 244)	θ value	1.87187e-05 (rank : 69)
Query Neighborhood Hits	1024	Target Neighborhood Hits	310	Shared Neighborhood Hits	171
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.315057 (rank : 245)	θ value	1.87187e-05 (rank : 70)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	171
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRAP_MOUSE
NC score	0.314491 (rank : 246)	θ value	5.44631e-05 (rank : 86)
Query Neighborhood Hits	1024	Target Neighborhood Hits	309	Shared Neighborhood Hits	175
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GLSK_HUMAN
NC score	0.314077 (rank : 247)	θ value	θ > 10 (rank : 1246)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	176
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

NUD12_MOUSE
NC score	0.312133 (rank : 248)	θ value	θ > 10 (rank : 1380)
Query Neighborhood Hits	1024	Target Neighborhood Hits	243	Shared Neighborhood Hits	207
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

GRAP_HUMAN
NC score	0.311734 (rank : 249)	θ value	9.29e-05 (rank : 93)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	177
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

CD2AP_HUMAN
NC score	0.309407 (rank : 250)	θ value	0.00665767 (rank : 258)
Query Neighborhood Hits	1024	Target Neighborhood Hits	315	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

GIT1_HUMAN
NC score	0.308696 (rank : 251)	θ value	1.81305 (rank : 738)
Query Neighborhood Hits	1024	Target Neighborhood Hits	336	Shared Neighborhood Hits	237
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
NC score	0.308603 (rank : 252)	θ value	1.81305 (rank : 739)
Query Neighborhood Hits	1024	Target Neighborhood Hits	341	Shared Neighborhood Hits	236
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

DDEF1_MOUSE
NC score	0.307238 (rank : 253)	θ value	0.163984 (rank : 480)
Query Neighborhood Hits	1024	Target Neighborhood Hits	592	Shared Neighborhood Hits	354
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

GIT2_MOUSE
NC score	0.304336 (rank : 254)	θ value	θ > 10 (rank : 1243)
Query Neighborhood Hits	1024	Target Neighborhood Hits	323	Shared Neighborhood Hits	237
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

UACA_HUMAN
NC score	0.304200 (rank : 255)	θ value	0.00298849 (rank : 221)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1622	Shared Neighborhood Hits	326
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

TNI3K_HUMAN
NC score	0.304019 (rank : 256)	θ value	0.000461057 (rank : 128)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1084	Shared Neighborhood Hits	317
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
NC score	0.303161 (rank : 257)	θ value	9.29e-05 (rank : 94)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1079	Shared Neighborhood Hits	317
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

NCK1_HUMAN
NC score	0.299873 (rank : 258)	θ value	0.00509761 (rank : 242)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	168
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

AN13A_HUMAN
NC score	0.299175 (rank : 259)	θ value	1.06291 (rank : 664)
Query Neighborhood Hits	1024	Target Neighborhood Hits	243	Shared Neighborhood Hits	209
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ASB14_HUMAN
NC score	0.298240 (rank : 260)	θ value	6.88961 (rank : 928)
Query Neighborhood Hits	1024	Target Neighborhood Hits	187	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

HCLS1_HUMAN
NC score	0.296209 (rank : 261)	θ value	0.0193708 (rank : 330)
Query Neighborhood Hits	1024	Target Neighborhood Hits	358	Shared Neighborhood Hits	221
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

NUD12_HUMAN
NC score	0.294395 (rank : 262)	θ value	θ > 10 (rank : 1379)
Query Neighborhood Hits	1024	Target Neighborhood Hits	222	Shared Neighborhood Hits	190
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CASL_MOUSE
NC score	0.294247 (rank : 263)	θ value	2.44474e-05 (rank : 76)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	154
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

TEX14_MOUSE
NC score	0.293616 (rank : 264)	θ value	0.62314 (rank : 625)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1333	Shared Neighborhood Hits	329
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

NCK2_HUMAN
NC score	0.292905 (rank : 265)	θ value	0.00298849 (rank : 214)
Query Neighborhood Hits	1024	Target Neighborhood Hits	310	Shared Neighborhood Hits	171
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

CASL_HUMAN
NC score	0.292560 (rank : 266)	θ value	2.44474e-05 (rank : 75)
Query Neighborhood Hits	1024	Target Neighborhood Hits	259	Shared Neighborhood Hits	162
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

ABI2_HUMAN
NC score	0.289644 (rank : 267)	θ value	0.00228821 (rank : 190)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	207
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

UACA_MOUSE
NC score	0.289488 (rank : 268)	θ value	0.00869519 (rank : 284)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1620	Shared Neighborhood Hits	322
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

AN13A_MOUSE
NC score	0.289483 (rank : 269)	θ value	0.125558 (rank : 460)
Query Neighborhood Hits	1024	Target Neighborhood Hits	226	Shared Neighborhood Hits	207
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

DGKZ_HUMAN
NC score	0.289187 (rank : 270)	θ value	0.00665767 (rank : 261)
Query Neighborhood Hits	1024	Target Neighborhood Hits	551	Shared Neighborhood Hits	211
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

TEX14_HUMAN
NC score	0.288616 (rank : 271)	θ value	5.27518 (rank : 917)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1103	Shared Neighborhood Hits	325
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

PPIP1_MOUSE
NC score	0.283731 (rank : 272)	θ value	0.00298849 (rank : 215)
Query Neighborhood Hits	1024	Target Neighborhood Hits	377	Shared Neighborhood Hits	169
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

TRPV5_MOUSE
NC score	0.281925 (rank : 273)	θ value	1.38821 (rank : 732)
Query Neighborhood Hits	1024	Target Neighborhood Hits	278	Shared Neighborhood Hits	227
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

GIT2_HUMAN
NC score	0.279782 (rank : 274)	θ value	θ > 10 (rank : 1242)
Query Neighborhood Hits	1024	Target Neighborhood Hits	381	Shared Neighborhood Hits	231
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

HCLS1_MOUSE
NC score	0.276713 (rank : 275)	θ value	0.125558 (rank : 467)
Query Neighborhood Hits	1024	Target Neighborhood Hits	329	Shared Neighborhood Hits	209
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

ANR26_MOUSE
NC score	0.276507 (rank : 276)	θ value	0.0563607 (rank : 402)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1554	Shared Neighborhood Hits	325
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DDFL1_HUMAN
NC score	0.276356 (rank : 277)	θ value	0.00175202 (rank : 182)
Query Neighborhood Hits	1024	Target Neighborhood Hits	353	Shared Neighborhood Hits	235
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

PPIP1_HUMAN
NC score	0.275537 (rank : 278)	θ value	0.00509761 (rank : 245)
Query Neighborhood Hits	1024	Target Neighborhood Hits	389	Shared Neighborhood Hits	170
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

NOTC4_MOUSE
NC score	0.274957 (rank : 279)	θ value	0.00509761 (rank : 243)
Query Neighborhood Hits	1024	Target Neighborhood Hits	872	Shared Neighborhood Hits	265
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PRRT3_HUMAN
NC score	0.274797 (rank : 280)	θ value	1.81305 (rank : 751)
Query Neighborhood Hits	1024	Target Neighborhood Hits	998	Shared Neighborhood Hits	412
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ABI2_MOUSE
NC score	0.273052 (rank : 281)	θ value	0.0113563 (rank : 285)
Query Neighborhood Hits	1024	Target Neighborhood Hits	266	Shared Neighborhood Hits	179
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

NOTC4_HUMAN
NC score	0.271555 (rank : 282)	θ value	0.00228821 (rank : 195)
Query Neighborhood Hits	1024	Target Neighborhood Hits	905	Shared Neighborhood Hits	280
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DGKZ_MOUSE
NC score	0.270906 (rank : 283)	θ value	0.0148317 (rank : 306)
Query Neighborhood Hits	1024	Target Neighborhood Hits	542	Shared Neighborhood Hits	200
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DNMBP_HUMAN
NC score	0.267395 (rank : 284)	θ value	0.00020696 (rank : 100)
Query Neighborhood Hits	1024	Target Neighborhood Hits	413	Shared Neighborhood Hits	192
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SH3G2_MOUSE
NC score	0.266446 (rank : 285)	θ value	0.00509761 (rank : 247)
Query Neighborhood Hits	1024	Target Neighborhood Hits	319	Shared Neighborhood Hits	161
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G2_HUMAN
NC score	0.266369 (rank : 286)	θ value	0.00869519 (rank : 281)
Query Neighborhood Hits	1024	Target Neighborhood Hits	324	Shared Neighborhood Hits	164
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G1_MOUSE
NC score	0.264999 (rank : 287)	θ value	0.00228821 (rank : 198)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	162
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

ANR26_HUMAN
NC score	0.264411 (rank : 288)	θ value	0.0431538 (rank : 379)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1614	Shared Neighborhood Hits	321
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

STAM2_MOUSE
NC score	0.264128 (rank : 289)	θ value	0.00869519 (rank : 283)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	169
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

DAPK1_MOUSE
NC score	0.262324 (rank : 290)	θ value	0.00035302 (rank : 117)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1138	Shared Neighborhood Hits	320
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DGKI_HUMAN
NC score	0.261819 (rank : 291)	θ value	0.00134147 (rank : 171)
Query Neighborhood Hits	1024	Target Neighborhood Hits	609	Shared Neighborhood Hits	207
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

CT012_MOUSE
NC score	0.261266 (rank : 292)	θ value	2.36792 (rank : 768)
Query Neighborhood Hits	1024	Target Neighborhood Hits	229	Shared Neighborhood Hits	168
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

STAM1_MOUSE
NC score	0.259655 (rank : 293)	θ value	0.0193708 (rank : 336)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	173
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

SON_HUMAN
NC score	0.259522 (rank : 294)	θ value	0.0563607 (rank : 419)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1568	Shared Neighborhood Hits	456
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

STAM1_HUMAN
NC score	0.259366 (rank : 295)	θ value	0.0193708 (rank : 335)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	172
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ARHG7_HUMAN
NC score	0.259294 (rank : 296)	θ value	0.00390308 (rank : 224)
Query Neighborhood Hits	1024	Target Neighborhood Hits	347	Shared Neighborhood Hits	170
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

SH3G3_MOUSE
NC score	0.259241 (rank : 297)	θ value	0.125558 (rank : 473)
Query Neighborhood Hits	1024	Target Neighborhood Hits	236	Shared Neighborhood Hits	156
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

TRPV5_HUMAN
NC score	0.258881 (rank : 298)	θ value	θ > 10 (rank : 1539)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

NOTC3_HUMAN
NC score	0.258744 (rank : 299)	θ value	0.00035302 (rank : 120)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1062	Shared Neighborhood Hits	357
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SH3G3_HUMAN
NC score	0.257703 (rank : 300)	θ value	0.0252991 (rank : 352)
Query Neighborhood Hits	1024	Target Neighborhood Hits	222	Shared Neighborhood Hits	154
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SRC8_MOUSE
NC score	0.257211 (rank : 301)	θ value	0.813845 (rank : 662)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	175
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

DAPK1_HUMAN
NC score	0.256697 (rank : 302)	θ value	0.000602161 (rank : 131)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1130	Shared Neighborhood Hits	321
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

NOTC2_HUMAN
NC score	0.256670 (rank : 303)	θ value	0.0330416 (rank : 371)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1113	Shared Neighborhood Hits	391
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ARHG7_MOUSE
NC score	0.255040 (rank : 304)	θ value	0.0252991 (rank : 342)
Query Neighborhood Hits	1024	Target Neighborhood Hits	396	Shared Neighborhood Hits	172
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

DNMBP_MOUSE
NC score	0.253876 (rank : 305)	θ value	0.00175202 (rank : 183)
Query Neighborhood Hits	1024	Target Neighborhood Hits	435	Shared Neighborhood Hits	196
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SH3G1_HUMAN
NC score	0.253848 (rank : 306)	θ value	0.0961366 (rank : 456)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	158
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

NOTC3_MOUSE
NC score	0.253558 (rank : 307)	θ value	0.00035302 (rank : 121)
Query Neighborhood Hits	1024	Target Neighborhood Hits	975	Shared Neighborhood Hits	304
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

BAT4_HUMAN
NC score	0.253383 (rank : 308)	θ value	0.0431538 (rank : 381)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	104
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

SRC8_HUMAN
NC score	0.253166 (rank : 309)	θ value	0.813845 (rank : 661)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	166
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

PACN2_HUMAN
NC score	0.252611 (rank : 310)	θ value	0.0431538 (rank : 389)
Query Neighborhood Hits	1024	Target Neighborhood Hits	339	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

NOTC2_MOUSE
NC score	0.251614 (rank : 311)	θ value	0.163984 (rank : 490)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1069	Shared Neighborhood Hits	364
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

STAC_HUMAN
NC score	0.249186 (rank : 312)	θ value	2.36792 (rank : 789)
Query Neighborhood Hits	1024	Target Neighborhood Hits	276	Shared Neighborhood Hits	158
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ABI1_MOUSE
NC score	0.248884 (rank : 313)	θ value	0.21417 (rank : 498)
Query Neighborhood Hits	1024	Target Neighborhood Hits	246	Shared Neighborhood Hits	172
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

TRPV6_HUMAN
NC score	0.247945 (rank : 314)	θ value	θ > 10 (rank : 1540)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	210
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

VINEX_MOUSE
NC score	0.247606 (rank : 315)	θ value	8.99809 (rank : 1022)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	181
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

NCF1_MOUSE
NC score	0.247548 (rank : 316)	θ value	0.21417 (rank : 513)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	145
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

PACN2_MOUSE
NC score	0.247529 (rank : 317)	θ value	0.0961366 (rank : 452)
Query Neighborhood Hits	1024	Target Neighborhood Hits	382	Shared Neighborhood Hits	168
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

STAC_MOUSE
NC score	0.247408 (rank : 318)	θ value	1.81305 (rank : 756)
Query Neighborhood Hits	1024	Target Neighborhood Hits	268	Shared Neighborhood Hits	154
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

BAT4_MOUSE
NC score	0.246847 (rank : 319)	θ value	0.0736092 (rank : 426)
Query Neighborhood Hits	1024	Target Neighborhood Hits	171	Shared Neighborhood Hits	119
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

SRBS1_MOUSE
NC score	0.246628 (rank : 320)	θ value	0.62314 (rank : 620)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	203
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

TCGAP_HUMAN
NC score	0.245350 (rank : 321)	θ value	0.0193708 (rank : 337)
Query Neighborhood Hits	1024	Target Neighborhood Hits	872	Shared Neighborhood Hits	413
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

NCF1_HUMAN
NC score	0.244672 (rank : 322)	θ value	0.365318 (rank : 563)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	140
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

PACN1_HUMAN
NC score	0.244567 (rank : 323)	θ value	0.0736092 (rank : 434)
Query Neighborhood Hits	1024	Target Neighborhood Hits	320	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
NC score	0.244378 (rank : 324)	θ value	0.0736092 (rank : 435)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	159
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

ABI1_HUMAN
NC score	0.243707 (rank : 325)	θ value	0.365318 (rank : 550)
Query Neighborhood Hits	1024	Target Neighborhood Hits	257	Shared Neighborhood Hits	177
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ARHG6_MOUSE
NC score	0.242421 (rank : 326)	θ value	0.0193708 (rank : 319)
Query Neighborhood Hits	1024	Target Neighborhood Hits	394	Shared Neighborhood Hits	170
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

NOTC1_HUMAN
NC score	0.242238 (rank : 327)	θ value	0.00390308 (rank : 229)
Query Neighborhood Hits	1024	Target Neighborhood Hits	906	Shared Neighborhood Hits	275
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

STAM2_HUMAN
NC score	0.242213 (rank : 328)	θ value	0.163984 (rank : 492)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	176
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

SRBS1_HUMAN
NC score	0.241487 (rank : 329)	θ value	0.813845 (rank : 660)
Query Neighborhood Hits	1024	Target Neighborhood Hits	396	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAC3_MOUSE
NC score	0.240929 (rank : 330)	θ value	0.365318 (rank : 569)
Query Neighborhood Hits	1024	Target Neighborhood Hits	232	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_HUMAN
NC score	0.240092 (rank : 331)	θ value	0.365318 (rank : 568)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	141
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CENG1_MOUSE
NC score	0.239943 (rank : 332)	θ value	0.000270298 (rank : 106)
Query Neighborhood Hits	1024	Target Neighborhood Hits	531	Shared Neighborhood Hits	272
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

AHI1_HUMAN
NC score	0.239837 (rank : 333)	θ value	4.1701e-05 (rank : 79)
Query Neighborhood Hits	1024	Target Neighborhood Hits	537	Shared Neighborhood Hits	174
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

NACAM_MOUSE
NC score	0.238736 (rank : 334)	θ value	4.92598e-06 (rank : 58)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1866	Shared Neighborhood Hits	451
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ARHG6_HUMAN
NC score	0.238464 (rank : 335)	θ value	0.00869519 (rank : 273)
Query Neighborhood Hits	1024	Target Neighborhood Hits	376	Shared Neighborhood Hits	166
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

VINEX_HUMAN
NC score	0.238122 (rank : 336)	θ value	θ > 10 (rank : 1554)
Query Neighborhood Hits	1024	Target Neighborhood Hits	270	Shared Neighborhood Hits	170
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

NCF2_HUMAN
NC score	0.237698 (rank : 337)	θ value	θ > 10 (rank : 1358)
Query Neighborhood Hits	1024	Target Neighborhood Hits	229	Shared Neighborhood Hits	147
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

CT012_HUMAN
NC score	0.236469 (rank : 338)	θ value	θ > 10 (rank : 1155)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

PACN3_MOUSE
NC score	0.234908 (rank : 339)	θ value	0.0193708 (rank : 334)
Query Neighborhood Hits	1024	Target Neighborhood Hits	380	Shared Neighborhood Hits	163
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PACN3_HUMAN
NC score	0.233091 (rank : 340)	θ value	0.0330416 (rank : 372)
Query Neighborhood Hits	1024	Target Neighborhood Hits	385	Shared Neighborhood Hits	163
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

BCL9_HUMAN
NC score	0.232309 (rank : 341)	θ value	0.21417 (rank : 500)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1008	Shared Neighborhood Hits	380
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CENG2_HUMAN
NC score	0.230842 (rank : 342)	θ value	0.365318 (rank : 554)
Query Neighborhood Hits	1024	Target Neighborhood Hits	471	Shared Neighborhood Hits	240
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG1_HUMAN
NC score	0.229494 (rank : 343)	θ value	4.03905 (rank : 855)
Query Neighborhood Hits	1024	Target Neighborhood Hits	544	Shared Neighborhood Hits	267
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG2_MOUSE
NC score	0.228637 (rank : 344)	θ value	0.62314 (rank : 606)
Query Neighborhood Hits	1024	Target Neighborhood Hits	463	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

AHI1_MOUSE
NC score	0.228002 (rank : 345)	θ value	0.000121331 (rank : 95)
Query Neighborhood Hits	1024	Target Neighborhood Hits	496	Shared Neighborhood Hits	172
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ITSN1_HUMAN
NC score	0.225976 (rank : 346)	θ value	1.69304e-06 (rank : 48)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1757	Shared Neighborhood Hits	322
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

CENG3_MOUSE
NC score	0.225798 (rank : 347)	θ value	0.0113563 (rank : 290)
Query Neighborhood Hits	1024	Target Neighborhood Hits	467	Shared Neighborhood Hits	229
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ITSN2_HUMAN
NC score	0.225709 (rank : 348)	θ value	4.92598e-06 (rank : 57)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1173	Shared Neighborhood Hits	222
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

VAV_HUMAN
NC score	0.225461 (rank : 349)	θ value	0.00134147 (rank : 176)
Query Neighborhood Hits	1024	Target Neighborhood Hits	452	Shared Neighborhood Hits	174
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

CENG3_HUMAN
NC score	0.225092 (rank : 350)	θ value	0.0113563 (rank : 289)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	225
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

PEX13_HUMAN
NC score	0.224568 (rank : 351)	θ value	0.0148317 (rank : 315)
Query Neighborhood Hits	1024	Target Neighborhood Hits	128	Shared Neighborhood Hits	102
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

VAV_MOUSE
NC score	0.224382 (rank : 352)	θ value	0.00175202 (rank : 189)
Query Neighborhood Hits	1024	Target Neighborhood Hits	430	Shared Neighborhood Hits	173
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

ITSN1_MOUSE
NC score	0.223843 (rank : 353)	θ value	1.09739e-05 (rank : 62)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1669	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

BCL9_MOUSE
NC score	0.222052 (rank : 354)	θ value	0.0148317 (rank : 302)
Query Neighborhood Hits	1024	Target Neighborhood Hits	770	Shared Neighborhood Hits	310
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CO5A2_HUMAN
NC score	0.221590 (rank : 355)	θ value	9.29e-05 (rank : 91)
Query Neighborhood Hits	1024	Target Neighborhood Hits	760	Shared Neighborhood Hits	250
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CRKL_HUMAN
NC score	0.217926 (rank : 356)	θ value	3.0926 (rank : 810)
Query Neighborhood Hits	1024	Target Neighborhood Hits	313	Shared Neighborhood Hits	170
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

PRP2_MOUSE
NC score	0.217917 (rank : 357)	θ value	4.0297e-08 (rank : 23)
Query Neighborhood Hits	1024	Target Neighborhood Hits	347	Shared Neighborhood Hits	149
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

NCOA6_HUMAN
NC score	0.216862 (rank : 358)	θ value	4.03905 (rank : 864)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1202	Shared Neighborhood Hits	412
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SSBP4_HUMAN
NC score	0.215260 (rank : 359)	θ value	6.88961 (rank : 956)
Query Neighborhood Hits	1024	Target Neighborhood Hits	753	Shared Neighborhood Hits	346
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

ITSN2_MOUSE
NC score	0.214795 (rank : 360)	θ value	4.1701e-05 (rank : 83)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1371	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ANM2_HUMAN
NC score	0.213729 (rank : 361)	θ value	3.19293e-05 (rank : 77)
Query Neighborhood Hits	1024	Target Neighborhood Hits	175	Shared Neighborhood Hits	134
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

PEX13_MOUSE
NC score	0.213579 (rank : 362)	θ value	0.0563607 (rank : 415)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

ARHG9_HUMAN
NC score	0.212943 (rank : 363)	θ value	0.00175202 (rank : 177)
Query Neighborhood Hits	1024	Target Neighborhood Hits	235	Shared Neighborhood Hits	144
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
NC score	0.212752 (rank : 364)	θ value	0.00175202 (rank : 178)
Query Neighborhood Hits	1024	Target Neighborhood Hits	234	Shared Neighborhood Hits	142
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

NPHP1_MOUSE
NC score	0.211630 (rank : 365)	θ value	θ > 10 (rank : 1371)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

SRRM1_MOUSE
NC score	0.211231 (rank : 366)	θ value	3.19293e-05 (rank : 78)
Query Neighborhood Hits	1024	Target Neighborhood Hits	966	Shared Neighborhood Hits	275
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ABI3_MOUSE
NC score	0.211127 (rank : 367)	θ value	1.81305 (rank : 735)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ARHG4_HUMAN
NC score	0.210856 (rank : 368)	θ value	0.0431538 (rank : 380)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CRKL_MOUSE
NC score	0.210056 (rank : 369)	θ value	3.0926 (rank : 811)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	160
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

DIDO1_HUMAN
NC score	0.209382 (rank : 370)	θ value	1.06291 (rank : 674)
Query Neighborhood Hits	1024	Target Neighborhood Hits	960	Shared Neighborhood Hits	304
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ANM2_MOUSE
NC score	0.207771 (rank : 371)	θ value	9.29e-05 (rank : 90)
Query Neighborhood Hits	1024	Target Neighborhood Hits	175	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

CO1A1_HUMAN
NC score	0.206427 (rank : 372)	θ value	7.59969e-07 (rank : 41)
Query Neighborhood Hits	1024	Target Neighborhood Hits	475	Shared Neighborhood Hits	164
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CRK_MOUSE
NC score	0.206241 (rank : 373)	θ value	θ > 10 (rank : 1145)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	165
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

BSN_MOUSE
NC score	0.205620 (rank : 374)	θ value	0.0961366 (rank : 445)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2057	Shared Neighborhood Hits	501
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

RGS3_MOUSE
NC score	0.205468 (rank : 375)	θ value	θ > 10 (rank : 1427)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1621	Shared Neighborhood Hits	481
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NOTC1_MOUSE
NC score	0.204543 (rank : 376)	θ value	0.125558 (rank : 469)
Query Neighborhood Hits	1024	Target Neighborhood Hits	916	Shared Neighborhood Hits	277
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CRK_HUMAN
NC score	0.202261 (rank : 377)	θ value	θ > 10 (rank : 1144)
Query Neighborhood Hits	1024	Target Neighborhood Hits	308	Shared Neighborhood Hits	163
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CO1A1_MOUSE
NC score	0.201799 (rank : 378)	θ value	2.88788e-06 (rank : 50)
Query Neighborhood Hits	1024	Target Neighborhood Hits	457	Shared Neighborhood Hits	162
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

PCLO_MOUSE
NC score	0.200653 (rank : 379)	θ value	0.0736092 (rank : 436)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2275	Shared Neighborhood Hits	531
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

VAV2_MOUSE
NC score	0.199947 (rank : 380)	θ value	0.0736092 (rank : 443)
Query Neighborhood Hits	1024	Target Neighborhood Hits	456	Shared Neighborhood Hits	184
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

NPHP1_HUMAN
NC score	0.199715 (rank : 381)	θ value	0.163984 (rank : 491)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	142
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

DBNL_MOUSE
NC score	0.198268 (rank : 382)	θ value	0.813845 (rank : 641)
Query Neighborhood Hits	1024	Target Neighborhood Hits	306	Shared Neighborhood Hits	146
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

ARI1A_HUMAN
NC score	0.198256 (rank : 383)	θ value	0.000270298 (rank : 104)
Query Neighborhood Hits	1024	Target Neighborhood Hits	787	Shared Neighborhood Hits	296
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

DBNL_HUMAN
NC score	0.197802 (rank : 384)	θ value	0.813845 (rank : 640)
Query Neighborhood Hits	1024	Target Neighborhood Hits	244	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

CO2A1_HUMAN
NC score	0.197714 (rank : 385)	θ value	4.1701e-05 (rank : 82)
Query Neighborhood Hits	1024	Target Neighborhood Hits	486	Shared Neighborhood Hits	179
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

VAV2_HUMAN
NC score	0.197047 (rank : 386)	θ value	0.0736092 (rank : 442)
Query Neighborhood Hits	1024	Target Neighborhood Hits	453	Shared Neighborhood Hits	171
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

PRB3_HUMAN
NC score	0.196570 (rank : 387)	θ value	8.11959e-09 (rank : 20)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	130
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CO3A1_MOUSE
NC score	0.196449 (rank : 388)	θ value	0.000270298 (rank : 107)
Query Neighborhood Hits	1024	Target Neighborhood Hits	466	Shared Neighborhood Hits	158
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

NCF4_MOUSE
NC score	0.195231 (rank : 389)	θ value	θ > 10 (rank : 1360)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	131
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

GRIN1_HUMAN
NC score	0.195207 (rank : 390)	θ value	0.0330416 (rank : 368)
Query Neighborhood Hits	1024	Target Neighborhood Hits	681	Shared Neighborhood Hits	242
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MDC1_HUMAN
NC score	0.195173 (rank : 391)	θ value	0.00509761 (rank : 240)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1446	Shared Neighborhood Hits	322
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CO1A2_MOUSE
NC score	0.195077 (rank : 392)	θ value	0.00175202 (rank : 180)
Query Neighborhood Hits	1024	Target Neighborhood Hits	388	Shared Neighborhood Hits	145
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A4_HUMAN
NC score	0.192886 (rank : 393)	θ value	0.0193708 (rank : 326)
Query Neighborhood Hits	1024	Target Neighborhood Hits	440	Shared Neighborhood Hits	173
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

WASIP_MOUSE
NC score	0.192694 (rank : 394)	θ value	0.000270298 (rank : 113)
Query Neighborhood Hits	1024	Target Neighborhood Hits	392	Shared Neighborhood Hits	166
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

MAGE1_HUMAN
NC score	0.192551 (rank : 395)	θ value	4.03905 (rank : 860)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1389	Shared Neighborhood Hits	421
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ABI3_HUMAN
NC score	0.192504 (rank : 396)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	162
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

LASP1_HUMAN
NC score	0.192307 (rank : 397)	θ value	1.06291 (rank : 688)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	143
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

PRP1_HUMAN
NC score	0.191818 (rank : 398)	θ value	1.87187e-05 (rank : 72)
Query Neighborhood Hits	1024	Target Neighborhood Hits	385	Shared Neighborhood Hits	158
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SON_MOUSE
NC score	0.190707 (rank : 399)	θ value	1.81305 (rank : 754)
Query Neighborhood Hits	1024	Target Neighborhood Hits	957	Shared Neighborhood Hits	291
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CO3A1_HUMAN
NC score	0.190368 (rank : 400)	θ value	0.000786445 (rank : 141)
Query Neighborhood Hits	1024	Target Neighborhood Hits	452	Shared Neighborhood Hits	154
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

LASP1_MOUSE
NC score	0.190346 (rank : 401)	θ value	1.06291 (rank : 689)
Query Neighborhood Hits	1024	Target Neighborhood Hits	297	Shared Neighborhood Hits	143
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

CO4A2_MOUSE
NC score	0.190243 (rank : 402)	θ value	0.0193708 (rank : 325)
Query Neighborhood Hits	1024	Target Neighborhood Hits	492	Shared Neighborhood Hits	191
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A3_HUMAN
NC score	0.189455 (rank : 403)	θ value	1.43324e-05 (rank : 66)
Query Neighborhood Hits	1024	Target Neighborhood Hits	421	Shared Neighborhood Hits	157
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

RUSC1_HUMAN
NC score	0.189303 (rank : 404)	θ value	0.0563607 (rank : 418)
Query Neighborhood Hits	1024	Target Neighborhood Hits	226	Shared Neighborhood Hits	147
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

NEBL_HUMAN
NC score	0.188848 (rank : 405)	θ value	0.0431538 (rank : 388)
Query Neighborhood Hits	1024	Target Neighborhood Hits	457	Shared Neighborhood Hits	158
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

OGFR_MOUSE
NC score	0.188743 (rank : 406)	θ value	θ > 10 (rank : 1384)
Query Neighborhood Hits	1024	Target Neighborhood Hits	584	Shared Neighborhood Hits	190
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PRB4S_HUMAN
NC score	0.188117 (rank : 407)	θ value	1.43324e-05 (rank : 67)
Query Neighborhood Hits	1024	Target Neighborhood Hits	330	Shared Neighborhood Hits	138
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

CO2A1_MOUSE
NC score	0.187134 (rank : 408)	θ value	0.0252991 (rank : 344)
Query Neighborhood Hits	1024	Target Neighborhood Hits	483	Shared Neighborhood Hits	165
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A2_HUMAN
NC score	0.187029 (rank : 409)	θ value	0.0148317 (rank : 304)
Query Neighborhood Hits	1024	Target Neighborhood Hits	454	Shared Neighborhood Hits	185
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COBA1_HUMAN
NC score	0.186633 (rank : 410)	θ value	0.0330416 (rank : 363)
Query Neighborhood Hits	1024	Target Neighborhood Hits	491	Shared Neighborhood Hits	175
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO5A3_HUMAN
NC score	0.186317 (rank : 411)	θ value	0.00509761 (rank : 235)
Query Neighborhood Hits	1024	Target Neighborhood Hits	433	Shared Neighborhood Hits	156
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

TAF4_HUMAN
NC score	0.186000 (rank : 412)	θ value	7.59969e-07 (rank : 43)
Query Neighborhood Hits	1024	Target Neighborhood Hits	687	Shared Neighborhood Hits	188
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CEL_HUMAN
NC score	0.185695 (rank : 413)	θ value	0.0563607 (rank : 405)
Query Neighborhood Hits	1024	Target Neighborhood Hits	896	Shared Neighborhood Hits	364
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CO5A1_MOUSE
NC score	0.185439 (rank : 414)	θ value	0.00175202 (rank : 181)
Query Neighborhood Hits	1024	Target Neighborhood Hits	419	Shared Neighborhood Hits	155
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CO1A2_HUMAN
NC score	0.184924 (rank : 415)	θ value	0.00298849 (rank : 208)
Query Neighborhood Hits	1024	Target Neighborhood Hits	329	Shared Neighborhood Hits	127
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO9A1_MOUSE
NC score	0.184777 (rank : 416)	θ value	0.279714 (rank : 525)
Query Neighborhood Hits	1024	Target Neighborhood Hits	477	Shared Neighborhood Hits	178
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

IKBL_MOUSE
NC score	0.184725 (rank : 417)	θ value	θ > 10 (rank : 1270)
Query Neighborhood Hits	1024	Target Neighborhood Hits	196	Shared Neighborhood Hits	144
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CO5A1_HUMAN
NC score	0.184622 (rank : 418)	θ value	0.00298849 (rank : 209)
Query Neighborhood Hits	1024	Target Neighborhood Hits	434	Shared Neighborhood Hits	158
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

ABTB1_MOUSE
NC score	0.184392 (rank : 419)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	171
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

IKBL_HUMAN
NC score	0.184250 (rank : 420)	θ value	θ > 10 (rank : 1269)
Query Neighborhood Hits	1024	Target Neighborhood Hits	168	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

WASIP_HUMAN
NC score	0.184145 (rank : 421)	θ value	0.00665767 (rank : 269)
Query Neighborhood Hits	1024	Target Neighborhood Hits	458	Shared Neighborhood Hits	157
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

MDC1_MOUSE
NC score	0.183790 (rank : 422)	θ value	0.21417 (rank : 512)
Query Neighborhood Hits	1024	Target Neighborhood Hits	998	Shared Neighborhood Hits	283
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CO4A1_MOUSE
NC score	0.183646 (rank : 423)	θ value	0.0563607 (rank : 407)
Query Neighborhood Hits	1024	Target Neighborhood Hits	450	Shared Neighborhood Hits	173
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

ANKZ1_MOUSE
NC score	0.183525 (rank : 424)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	1024	Target Neighborhood Hits	208	Shared Neighborhood Hits	146
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

COBA2_MOUSE
NC score	0.183307 (rank : 425)	θ value	0.0113563 (rank : 291)
Query Neighborhood Hits	1024	Target Neighborhood Hits	501	Shared Neighborhood Hits	172
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COBA1_MOUSE
NC score	0.183147 (rank : 426)	θ value	0.47712 (rank : 580)
Query Neighborhood Hits	1024	Target Neighborhood Hits	487	Shared Neighborhood Hits	176
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

VAV3_MOUSE
NC score	0.182436 (rank : 427)	θ value	2.36792 (rank : 792)
Query Neighborhood Hits	1024	Target Neighborhood Hits	404	Shared Neighborhood Hits	170
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

NCF4_HUMAN
NC score	0.182211 (rank : 428)	θ value	θ > 10 (rank : 1359)
Query Neighborhood Hits	1024	Target Neighborhood Hits	161	Shared Neighborhood Hits	117
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

CO4A1_HUMAN
NC score	0.182179 (rank : 429)	θ value	0.47712 (rank : 579)
Query Neighborhood Hits	1024	Target Neighborhood Hits	425	Shared Neighborhood Hits	165
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

VAV3_HUMAN
NC score	0.182038 (rank : 430)	θ value	θ > 10 (rank : 1553)
Query Neighborhood Hits	1024	Target Neighborhood Hits	398	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

COBA2_HUMAN
NC score	0.182007 (rank : 431)	θ value	0.00869519 (rank : 275)
Query Neighborhood Hits	1024	Target Neighborhood Hits	408	Shared Neighborhood Hits	143
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

NCOA6_MOUSE
NC score	0.181548 (rank : 432)	θ value	θ > 10 (rank : 1361)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1076	Shared Neighborhood Hits	368
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MISS_MOUSE
NC score	0.179445 (rank : 433)	θ value	6.88961 (rank : 943)
Query Neighborhood Hits	1024	Target Neighborhood Hits	444	Shared Neighborhood Hits	220
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

CO9A1_HUMAN
NC score	0.177799 (rank : 434)	θ value	0.813845 (rank : 638)
Query Neighborhood Hits	1024	Target Neighborhood Hits	420	Shared Neighborhood Hits	144
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

ANKZ1_HUMAN
NC score	0.177470 (rank : 435)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	1024	Target Neighborhood Hits	236	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

MTSS1_MOUSE
NC score	0.176902 (rank : 436)	θ value	0.00869519 (rank : 279)
Query Neighborhood Hits	1024	Target Neighborhood Hits	592	Shared Neighborhood Hits	242
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

WBP11_MOUSE
NC score	0.176619 (rank : 437)	θ value	1.87187e-05 (rank : 73)
Query Neighborhood Hits	1024	Target Neighborhood Hits	362	Shared Neighborhood Hits	138
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ZN385_HUMAN
NC score	0.175834 (rank : 438)	θ value	θ > 10 (rank : 1565)
Query Neighborhood Hits	1024	Target Neighborhood Hits	614	Shared Neighborhood Hits	266
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SC24C_HUMAN
NC score	0.175621 (rank : 439)	θ value	5.27518 (rank : 916)
Query Neighborhood Hits	1024	Target Neighborhood Hits	662	Shared Neighborhood Hits	301
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CO9A2_MOUSE
NC score	0.175315 (rank : 440)	θ value	0.0193708 (rank : 327)
Query Neighborhood Hits	1024	Target Neighborhood Hits	279	Shared Neighborhood Hits	118
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

BAT2_HUMAN
NC score	0.175261 (rank : 441)	θ value	0.813845 (rank : 633)
Query Neighborhood Hits	1024	Target Neighborhood Hits	931	Shared Neighborhood Hits	315
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PLCG2_HUMAN
NC score	0.174868 (rank : 442)	θ value	0.279714 (rank : 541)
Query Neighborhood Hits	1024	Target Neighborhood Hits	280	Shared Neighborhood Hits	144
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

CO4A6_HUMAN
NC score	0.174403 (rank : 443)	θ value	2.36792 (rank : 767)
Query Neighborhood Hits	1024	Target Neighborhood Hits	318	Shared Neighborhood Hits	116
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

LCP2_HUMAN
NC score	0.174176 (rank : 444)	θ value	θ > 10 (rank : 1305)
Query Neighborhood Hits	1024	Target Neighborhood Hits	531	Shared Neighborhood Hits	230
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CO9A3_HUMAN
NC score	0.173390 (rank : 445)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	1024	Target Neighborhood Hits	361	Shared Neighborhood Hits	140
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COHA1_MOUSE
NC score	0.172844 (rank : 446)	θ value	0.125558 (rank : 463)
Query Neighborhood Hits	1024	Target Neighborhood Hits	414	Shared Neighborhood Hits	148
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

RHG04_HUMAN
NC score	0.172515 (rank : 447)	θ value	0.0330416 (rank : 373)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	148
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

PI5PA_HUMAN
NC score	0.172191 (rank : 448)	θ value	0.813845 (rank : 652)
Query Neighborhood Hits	1024	Target Neighborhood Hits	749	Shared Neighborhood Hits	316
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SRGP2_MOUSE
NC score	0.172155 (rank : 449)	θ value	0.00298849 (rank : 219)
Query Neighborhood Hits	1024	Target Neighborhood Hits	324	Shared Neighborhood Hits	145
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

MLL3_HUMAN
NC score	0.171488 (rank : 450)	θ value	0.62314 (rank : 615)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1644	Shared Neighborhood Hits	379
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TARSH_HUMAN
NC score	0.170869 (rank : 451)	θ value	0.0431538 (rank : 392)
Query Neighborhood Hits	1024	Target Neighborhood Hits	768	Shared Neighborhood Hits	255
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CO4A5_HUMAN
NC score	0.170240 (rank : 452)	θ value	0.00665767 (rank : 259)
Query Neighborhood Hits	1024	Target Neighborhood Hits	383	Shared Neighborhood Hits	144
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

SRGP2_HUMAN
NC score	0.170039 (rank : 453)	θ value	0.00228821 (rank : 199)
Query Neighborhood Hits	1024	Target Neighborhood Hits	331	Shared Neighborhood Hits	147
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

PELP1_MOUSE
NC score	0.169684 (rank : 454)	θ value	0.00509761 (rank : 244)
Query Neighborhood Hits	1024	Target Neighborhood Hits	709	Shared Neighborhood Hits	249
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

ZIM10_HUMAN
NC score	0.168941 (rank : 455)	θ value	0.0563607 (rank : 422)
Query Neighborhood Hits	1024	Target Neighborhood Hits	577	Shared Neighborhood Hits	270
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

COGA1_HUMAN
NC score	0.168766 (rank : 456)	θ value	0.0113563 (rank : 292)
Query Neighborhood Hits	1024	Target Neighborhood Hits	345	Shared Neighborhood Hits	131
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

PCLO_HUMAN
NC score	0.168018 (rank : 457)	θ value	0.000602161 (rank : 132)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2046	Shared Neighborhood Hits	405
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

COIA1_HUMAN
NC score	0.167819 (rank : 458)	θ value	0.00509761 (rank : 236)
Query Neighborhood Hits	1024	Target Neighborhood Hits	447	Shared Neighborhood Hits	177
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

WBP11_HUMAN
NC score	0.167598 (rank : 459)	θ value	1.43324e-05 (rank : 68)
Query Neighborhood Hits	1024	Target Neighborhood Hits	354	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

SPT5H_HUMAN
NC score	0.167505 (rank : 460)	θ value	0.00298849 (rank : 217)
Query Neighborhood Hits	1024	Target Neighborhood Hits	436	Shared Neighborhood Hits	194
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
NC score	0.167405 (rank : 461)	θ value	0.00298849 (rank : 218)
Query Neighborhood Hits	1024	Target Neighborhood Hits	437	Shared Neighborhood Hits	192
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

CPSF6_MOUSE
NC score	0.167083 (rank : 462)	θ value	0.00102713 (rank : 154)
Query Neighborhood Hits	1024	Target Neighborhood Hits	356	Shared Neighborhood Hits	143
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CPSF6_HUMAN
NC score	0.166695 (rank : 463)	θ value	0.00102713 (rank : 153)
Query Neighborhood Hits	1024	Target Neighborhood Hits	359	Shared Neighborhood Hits	142
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CO9A2_HUMAN
NC score	0.166569 (rank : 464)	θ value	0.0330416 (rank : 362)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	103
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

BAT2_MOUSE
NC score	0.164534 (rank : 465)	θ value	1.38821 (rank : 705)
Query Neighborhood Hits	1024	Target Neighborhood Hits	947	Shared Neighborhood Hits	337
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

COIA1_MOUSE
NC score	0.164046 (rank : 466)	θ value	0.163984 (rank : 479)
Query Neighborhood Hits	1024	Target Neighborhood Hits	481	Shared Neighborhood Hits	163
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COHA1_HUMAN
NC score	0.164004 (rank : 467)	θ value	0.0148317 (rank : 305)
Query Neighborhood Hits	1024	Target Neighborhood Hits	400	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

SRRM1_HUMAN
NC score	0.163771 (rank : 468)	θ value	0.00102713 (rank : 163)
Query Neighborhood Hits	1024	Target Neighborhood Hits	690	Shared Neighborhood Hits	181
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

RUSC1_MOUSE
NC score	0.163380 (rank : 469)	θ value	0.365318 (rank : 566)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	131
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

CONA1_HUMAN
NC score	0.163363 (rank : 470)	θ value	4.03905 (rank : 856)
Query Neighborhood Hits	1024	Target Neighborhood Hits	281	Shared Neighborhood Hits	116
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

ZIMP7_MOUSE
NC score	0.162779 (rank : 471)	θ value	θ > 10 (rank : 1564)
Query Neighborhood Hits	1024	Target Neighborhood Hits	566	Shared Neighborhood Hits	280
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

K1802_MOUSE
NC score	0.161802 (rank : 472)	θ value	0.0330416 (rank : 370)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1596	Shared Neighborhood Hits	353
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TCGAP_MOUSE
NC score	0.160905 (rank : 473)	θ value	0.0252991 (rank : 354)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	200
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

PLCG1_MOUSE
NC score	0.160668 (rank : 474)	θ value	8.99809 (rank : 1004)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	149
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

COAA1_MOUSE
NC score	0.160470 (rank : 475)	θ value	0.0736092 (rank : 428)
Query Neighborhood Hits	1024	Target Neighborhood Hits	286	Shared Neighborhood Hits	114
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

SRGP1_HUMAN
NC score	0.159369 (rank : 476)	θ value	0.0113563 (rank : 297)
Query Neighborhood Hits	1024	Target Neighborhood Hits	390	Shared Neighborhood Hits	149
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

COJA1_HUMAN
NC score	0.159221 (rank : 477)	θ value	θ > 10 (rank : 1142)
Query Neighborhood Hits	1024	Target Neighborhood Hits	323	Shared Neighborhood Hits	121
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CLR59_HUMAN
NC score	0.158973 (rank : 478)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	1024	Target Neighborhood Hits	163	Shared Neighborhood Hits	132
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

BSN_HUMAN
NC score	0.158926 (rank : 479)	θ value	0.21417 (rank : 501)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1537	Shared Neighborhood Hits	374
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MLL2_HUMAN
NC score	0.158718 (rank : 480)	θ value	0.00665767 (rank : 265)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1788	Shared Neighborhood Hits	380
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CO8A2_HUMAN
NC score	0.158477 (rank : 481)	θ value	0.125558 (rank : 462)
Query Neighborhood Hits	1024	Target Neighborhood Hits	299	Shared Neighborhood Hits	133
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

NEBU_HUMAN
NC score	0.157418 (rank : 482)	θ value	2.36792 (rank : 780)
Query Neighborhood Hits	1024	Target Neighborhood Hits	420	Shared Neighborhood Hits	154
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

CONA1_MOUSE
NC score	0.157238 (rank : 483)	θ value	θ > 10 (rank : 1143)
Query Neighborhood Hits	1024	Target Neighborhood Hits	254	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

SCAR3_MOUSE
NC score	0.157203 (rank : 484)	θ value	0.00102713 (rank : 161)
Query Neighborhood Hits	1024	Target Neighborhood Hits	239	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

CO8A1_HUMAN
NC score	0.156805 (rank : 485)	θ value	0.00665767 (rank : 260)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	119
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

SCAR3_HUMAN
NC score	0.156805 (rank : 486)	θ value	0.00102713 (rank : 160)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	77
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

ABTB1_HUMAN
NC score	0.156731 (rank : 487)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	1024	Target Neighborhood Hits	325	Shared Neighborhood Hits	156
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

CO7A1_HUMAN
NC score	0.156715 (rank : 488)	θ value	0.0563607 (rank : 408)
Query Neighborhood Hits	1024	Target Neighborhood Hits	807	Shared Neighborhood Hits	199
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

ARHG4_MOUSE
NC score	0.156462 (rank : 489)	θ value	6.88961 (rank : 926)
Query Neighborhood Hits	1024	Target Neighborhood Hits	185	Shared Neighborhood Hits	104
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

PLCG1_HUMAN
NC score	0.154850 (rank : 490)	θ value	8.99809 (rank : 1003)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	141
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

ANKR9_MOUSE
NC score	0.154555 (rank : 491)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	1024	Target Neighborhood Hits	120	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

CIC_HUMAN
NC score	0.154005 (rank : 492)	θ value	0.0431538 (rank : 383)
Query Neighborhood Hits	1024	Target Neighborhood Hits	992	Shared Neighborhood Hits	330
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO8A2_MOUSE
NC score	0.153299 (rank : 493)	θ value	0.0961366 (rank : 446)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	120
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CRSP2_HUMAN
NC score	0.151689 (rank : 494)	θ value	0.000461057 (rank : 125)
Query Neighborhood Hits	1024	Target Neighborhood Hits	380	Shared Neighborhood Hits	161
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

SRRM2_MOUSE
NC score	0.151639 (rank : 495)	θ value	0.0736092 (rank : 440)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1470	Shared Neighborhood Hits	315
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

COAA1_HUMAN
NC score	0.151097 (rank : 496)	θ value	0.0961366 (rank : 447)
Query Neighborhood Hits	1024	Target Neighborhood Hits	316	Shared Neighborhood Hits	120
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

PSL1_HUMAN
NC score	0.150518 (rank : 497)	θ value	0.0563607 (rank : 417)
Query Neighborhood Hits	1024	Target Neighborhood Hits	650	Shared Neighborhood Hits	281
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SLAP2_HUMAN
NC score	0.150352 (rank : 498)	θ value	8.99809 (rank : 1013)
Query Neighborhood Hits	1024	Target Neighborhood Hits	139	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

CO8A1_MOUSE
NC score	0.150169 (rank : 499)	θ value	0.0563607 (rank : 409)
Query Neighborhood Hits	1024	Target Neighborhood Hits	251	Shared Neighborhood Hits	108
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

SLAP2_MOUSE
NC score	0.149956 (rank : 500)	θ value	θ > 10 (rank : 1484)
Query Neighborhood Hits	1024	Target Neighborhood Hits	136	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

FNBP2_HUMAN
NC score	0.149821 (rank : 501)	θ value	0.125558 (rank : 466)
Query Neighborhood Hits	1024	Target Neighborhood Hits	432	Shared Neighborhood Hits	162
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

ES8L3_MOUSE
NC score	0.149351 (rank : 502)	θ value	θ > 10 (rank : 1219)
Query Neighborhood Hits	1024	Target Neighborhood Hits	168	Shared Neighborhood Hits	124
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

NFH_MOUSE
NC score	0.146817 (rank : 503)	θ value	θ > 10 (rank : 1364)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2247	Shared Neighborhood Hits	450
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MUCDL_HUMAN
NC score	0.146570 (rank : 504)	θ value	1.38821 (rank : 719)
Query Neighborhood Hits	1024	Target Neighborhood Hits	777	Shared Neighborhood Hits	263
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

RGS3_HUMAN
NC score	0.146379 (rank : 505)	θ value	θ > 10 (rank : 1426)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1375	Shared Neighborhood Hits	388
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ES8L3_HUMAN
NC score	0.146333 (rank : 506)	θ value	1.38821 (rank : 712)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	129
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

CN032_MOUSE
NC score	0.144697 (rank : 507)	θ value	0.00509761 (rank : 234)
Query Neighborhood Hits	1024	Target Neighborhood Hits	233	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

SLAP1_HUMAN
NC score	0.144287 (rank : 508)	θ value	θ > 10 (rank : 1482)
Query Neighborhood Hits	1024	Target Neighborhood Hits	113	Shared Neighborhood Hits	46
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

NOXO1_MOUSE
NC score	0.143612 (rank : 509)	θ value	θ > 10 (rank : 1370)
Query Neighborhood Hits	1024	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

SAPS1_HUMAN
NC score	0.143532 (rank : 510)	θ value	3.0926 (rank : 833)
Query Neighborhood Hits	1024	Target Neighborhood Hits	704	Shared Neighborhood Hits	284
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CO039_MOUSE
NC score	0.143132 (rank : 511)	θ value	1.06291 (rank : 673)
Query Neighborhood Hits	1024	Target Neighborhood Hits	445	Shared Neighborhood Hits	190
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CK024_HUMAN
NC score	0.142664 (rank : 512)	θ value	6.88961 (rank : 932)
Query Neighborhood Hits	1024	Target Neighborhood Hits	408	Shared Neighborhood Hits	167
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SRRM2_HUMAN
NC score	0.142639 (rank : 513)	θ value	0.00390308 (rank : 230)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1296	Shared Neighborhood Hits	259
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PRR12_HUMAN
NC score	0.142001 (rank : 514)	θ value	0.47712 (rank : 592)
Query Neighborhood Hits	1024	Target Neighborhood Hits	460	Shared Neighborhood Hits	159
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SLAP1_MOUSE
NC score	0.141880 (rank : 515)	θ value	θ > 10 (rank : 1483)
Query Neighborhood Hits	1024	Target Neighborhood Hits	117	Shared Neighborhood Hits	45
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SNPC4_HUMAN
NC score	0.141876 (rank : 516)	θ value	θ > 10 (rank : 1491)
Query Neighborhood Hits	1024	Target Neighborhood Hits	589	Shared Neighborhood Hits	259
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

RIMB2_HUMAN
NC score	0.141510 (rank : 517)	θ value	1.81305 (rank : 752)
Query Neighborhood Hits	1024	Target Neighborhood Hits	263	Shared Neighborhood Hits	120
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

CBP_MOUSE
NC score	0.141190 (rank : 518)	θ value	3.0926 (rank : 806)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1051	Shared Neighborhood Hits	308
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

EMID1_MOUSE
NC score	0.141098 (rank : 519)	θ value	0.279714 (rank : 528)
Query Neighborhood Hits	1024	Target Neighborhood Hits	230	Shared Neighborhood Hits	103
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

CO6A2_HUMAN
NC score	0.141050 (rank : 520)	θ value	0.21417 (rank : 504)
Query Neighborhood Hits	1024	Target Neighborhood Hits	249	Shared Neighborhood Hits	96
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

WIRE_HUMAN
NC score	0.140512 (rank : 521)	θ value	0.21417 (rank : 518)
Query Neighborhood Hits	1024	Target Neighborhood Hits	329	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

EMID1_HUMAN
NC score	0.139771 (rank : 522)	θ value	0.47712 (rank : 582)
Query Neighborhood Hits	1024	Target Neighborhood Hits	215	Shared Neighborhood Hits	100
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

COLQ_HUMAN
NC score	0.139461 (rank : 523)	θ value	3.0926 (rank : 809)
Query Neighborhood Hits	1024	Target Neighborhood Hits	193	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

MLL3_MOUSE
NC score	0.139275 (rank : 524)	θ value	θ > 10 (rank : 1340)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1399	Shared Neighborhood Hits	332
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

GSCR1_HUMAN
NC score	0.139201 (rank : 525)	θ value	5.27518 (rank : 899)
Query Neighborhood Hits	1024	Target Neighborhood Hits	674	Shared Neighborhood Hits	216
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

ES8L1_HUMAN
NC score	0.139125 (rank : 526)	θ value	2.36792 (rank : 773)
Query Neighborhood Hits	1024	Target Neighborhood Hits	162	Shared Neighborhood Hits	103
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

EMID2_HUMAN
NC score	0.138124 (rank : 527)	θ value	1.06291 (rank : 675)
Query Neighborhood Hits	1024	Target Neighborhood Hits	226	Shared Neighborhood Hits	105
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

CO6A2_MOUSE
NC score	0.137701 (rank : 528)	θ value	0.813845 (rank : 637)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	94
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

EDA_HUMAN
NC score	0.137604 (rank : 529)	θ value	0.163984 (rank : 483)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	76
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

CO6A1_HUMAN
NC score	0.137260 (rank : 530)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	94
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

NRX2B_HUMAN
NC score	0.137049 (rank : 531)	θ value	θ > 10 (rank : 1373)
Query Neighborhood Hits	1024	Target Neighborhood Hits	481	Shared Neighborhood Hits	245
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

RIMB1_HUMAN
NC score	0.137033 (rank : 532)	θ value	1.06291 (rank : 699)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1479	Shared Neighborhood Hits	331
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

LPP_HUMAN
NC score	0.136786 (rank : 533)	θ value	3.0926 (rank : 819)
Query Neighborhood Hits	1024	Target Neighborhood Hits	775	Shared Neighborhood Hits	293
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

CO6A1_MOUSE
NC score	0.136617 (rank : 534)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	1024	Target Neighborhood Hits	241	Shared Neighborhood Hits	89
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

WIRE_MOUSE
NC score	0.136367 (rank : 535)	θ value	0.62314 (rank : 628)
Query Neighborhood Hits	1024	Target Neighborhood Hits	310	Shared Neighborhood Hits	136
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

EDA_MOUSE
NC score	0.135588 (rank : 536)	θ value	0.279714 (rank : 527)
Query Neighborhood Hits	1024	Target Neighborhood Hits	141	Shared Neighborhood Hits	75
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

BAT3_MOUSE
NC score	0.135309 (rank : 537)	θ value	4.03905 (rank : 850)
Query Neighborhood Hits	1024	Target Neighborhood Hits	518	Shared Neighborhood Hits	214
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

RIMB2_MOUSE
NC score	0.135021 (rank : 538)	θ value	5.27518 (rank : 914)
Query Neighborhood Hits	1024	Target Neighborhood Hits	246	Shared Neighborhood Hits	104
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

MARCO_MOUSE
NC score	0.134988 (rank : 539)	θ value	θ > 10 (rank : 1323)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	83
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

ATN1_HUMAN
NC score	0.134950 (rank : 540)	θ value	1.06291 (rank : 669)
Query Neighborhood Hits	1024	Target Neighborhood Hits	676	Shared Neighborhood Hits	183
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

FYN_MOUSE
NC score	0.134705 (rank : 541)	θ value	0.000270298 (rank : 109)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1073	Shared Neighborhood Hits	202
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

RERE_HUMAN
NC score	0.134481 (rank : 542)	θ value	0.00298849 (rank : 216)
Query Neighborhood Hits	1024	Target Neighborhood Hits	779	Shared Neighborhood Hits	225
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

EP300_HUMAN
NC score	0.134445 (rank : 543)	θ value	0.279714 (rank : 529)
Query Neighborhood Hits	1024	Target Neighborhood Hits	821	Shared Neighborhood Hits	290
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

YLPM1_HUMAN
NC score	0.134046 (rank : 544)	θ value	0.163984 (rank : 495)
Query Neighborhood Hits	1024	Target Neighborhood Hits	670	Shared Neighborhood Hits	210
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

JPH2_HUMAN
NC score	0.133985 (rank : 545)	θ value	0.0736092 (rank : 431)
Query Neighborhood Hits	1024	Target Neighborhood Hits	639	Shared Neighborhood Hits	263
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SNX18_MOUSE
NC score	0.133839 (rank : 546)	θ value	0.279714 (rank : 548)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	116
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

ZIM10_MOUSE
NC score	0.133339 (rank : 547)	θ value	0.163984 (rank : 496)
Query Neighborhood Hits	1024	Target Neighborhood Hits	430	Shared Neighborhood Hits	216
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MYO1F_HUMAN
NC score	0.133172 (rank : 548)	θ value	0.000270298 (rank : 110)
Query Neighborhood Hits	1024	Target Neighborhood Hits	275	Shared Neighborhood Hits	169
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

FGR_MOUSE
NC score	0.133122 (rank : 549)	θ value	9.29e-05 (rank : 92)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1069	Shared Neighborhood Hits	204
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

COFA1_MOUSE
NC score	0.133021 (rank : 550)	θ value	θ > 10 (rank : 1141)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	113
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CN032_HUMAN
NC score	0.132840 (rank : 551)	θ value	0.125558 (rank : 461)
Query Neighborhood Hits	1024	Target Neighborhood Hits	267	Shared Neighborhood Hits	114
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

FYN_HUMAN
NC score	0.132698 (rank : 552)	θ value	0.000270298 (rank : 108)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1078	Shared Neighborhood Hits	202
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

YES_HUMAN
NC score	0.132522 (rank : 553)	θ value	0.000270298 (rank : 114)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1059	Shared Neighborhood Hits	204
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ES8L1_MOUSE
NC score	0.132198 (rank : 554)	θ value	0.125558 (rank : 465)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	93
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

YES_MOUSE
NC score	0.132191 (rank : 555)	θ value	0.000786445 (rank : 150)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1052	Shared Neighborhood Hits	201
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ALEX_HUMAN
NC score	0.131361 (rank : 556)	θ value	0.0431538 (rank : 378)
Query Neighborhood Hits	1024	Target Neighborhood Hits	361	Shared Neighborhood Hits	148
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

MYO1F_MOUSE
NC score	0.130998 (rank : 557)	θ value	0.00035302 (rank : 119)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	160
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

FYB_HUMAN
NC score	0.130614 (rank : 558)	θ value	0.365318 (rank : 557)
Query Neighborhood Hits	1024	Target Neighborhood Hits	379	Shared Neighborhood Hits	151
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

ANKF1_HUMAN
NC score	0.130404 (rank : 559)	θ value	1.06291 (rank : 665)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

FGR_HUMAN
NC score	0.130360 (rank : 560)	θ value	0.0148317 (rank : 307)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1067	Shared Neighborhood Hits	202
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

CECR2_HUMAN
NC score	0.130176 (rank : 561)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	1024	Target Neighborhood Hits	543	Shared Neighborhood Hits	245
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

RERE_MOUSE
NC score	0.130143 (rank : 562)	θ value	0.0961366 (rank : 454)
Query Neighborhood Hits	1024	Target Neighborhood Hits	785	Shared Neighborhood Hits	218
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SPTA2_HUMAN
NC score	0.129699 (rank : 563)	θ value	0.0113563 (rank : 296)
Query Neighborhood Hits	1024	Target Neighborhood Hits	888	Shared Neighborhood Hits	183
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SNX18_HUMAN
NC score	0.129507 (rank : 564)	θ value	1.06291 (rank : 702)
Query Neighborhood Hits	1024	Target Neighborhood Hits	207	Shared Neighborhood Hits	119
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

EMID2_MOUSE
NC score	0.129301 (rank : 565)	θ value	5.27518 (rank : 890)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	95
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

TAU_HUMAN
NC score	0.128861 (rank : 566)	θ value	2.36792 (rank : 790)
Query Neighborhood Hits	1024	Target Neighborhood Hits	448	Shared Neighborhood Hits	183
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

SRC_HUMAN
NC score	0.128645 (rank : 567)	θ value	0.000786445 (rank : 149)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1058	Shared Neighborhood Hits	205
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

GPS2_HUMAN
NC score	0.128417 (rank : 568)	θ value	0.00134147 (rank : 172)
Query Neighborhood Hits	1024	Target Neighborhood Hits	459	Shared Neighborhood Hits	126
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

ENAH_MOUSE
NC score	0.128185 (rank : 569)	θ value	0.00228821 (rank : 193)
Query Neighborhood Hits	1024	Target Neighborhood Hits	919	Shared Neighborhood Hits	196
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

COFA1_HUMAN
NC score	0.128176 (rank : 570)	θ value	θ > 10 (rank : 1140)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	108
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

SET1A_HUMAN
NC score	0.128146 (rank : 571)	θ value	0.00102713 (rank : 162)
Query Neighborhood Hits	1024	Target Neighborhood Hits	690	Shared Neighborhood Hits	167
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

BAT3_HUMAN
NC score	0.127989 (rank : 572)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	1024	Target Neighborhood Hits	490	Shared Neighborhood Hits	219
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

MYO1E_HUMAN
NC score	0.127788 (rank : 573)	θ value	0.00509761 (rank : 241)
Query Neighborhood Hits	1024	Target Neighborhood Hits	293	Shared Neighborhood Hits	165
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

CD2_HUMAN
NC score	0.127389 (rank : 574)	θ value	8.99809 (rank : 978)
Query Neighborhood Hits	1024	Target Neighborhood Hits	504	Shared Neighborhood Hits	200
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

ES8L2_HUMAN
NC score	0.127264 (rank : 575)	θ value	θ > 10 (rank : 1217)
Query Neighborhood Hits	1024	Target Neighborhood Hits	193	Shared Neighborhood Hits	135
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

RHG26_HUMAN
NC score	0.126982 (rank : 576)	θ value	2.36792 (rank : 784)
Query Neighborhood Hits	1024	Target Neighborhood Hits	281	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

MBD6_HUMAN
NC score	0.126839 (rank : 577)	θ value	θ > 10 (rank : 1326)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	125
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MUC7_HUMAN
NC score	0.126603 (rank : 578)	θ value	5.27518 (rank : 906)
Query Neighborhood Hits	1024	Target Neighborhood Hits	538	Shared Neighborhood Hits	137
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

YLPM1_MOUSE
NC score	0.126369 (rank : 579)	θ value	0.0961366 (rank : 457)
Query Neighborhood Hits	1024	Target Neighborhood Hits	505	Shared Neighborhood Hits	148
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CTDP1_HUMAN
NC score	0.124221 (rank : 580)	θ value	2.36792 (rank : 769)
Query Neighborhood Hits	1024	Target Neighborhood Hits	416	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

HCK_HUMAN
NC score	0.124006 (rank : 581)	θ value	0.000461057 (rank : 126)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1035	Shared Neighborhood Hits	195
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
NC score	0.123591 (rank : 582)	θ value	0.000786445 (rank : 144)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1029	Shared Neighborhood Hits	196
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

ANKR9_HUMAN
NC score	0.123292 (rank : 583)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	1024	Target Neighborhood Hits	99	Shared Neighborhood Hits	90
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

SRC_MOUSE
NC score	0.122722 (rank : 584)	θ value	0.000270298 (rank : 112)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1033	Shared Neighborhood Hits	198
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

RP1L1_HUMAN
NC score	0.122248 (rank : 585)	θ value	0.000270298 (rank : 111)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1072	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

WASL_HUMAN
NC score	0.122008 (rank : 586)	θ value	4.03905 (rank : 874)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	135
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
NC score	0.121942 (rank : 587)	θ value	0.47712 (rank : 601)
Query Neighborhood Hits	1024	Target Neighborhood Hits	339	Shared Neighborhood Hits	131
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

M3K11_HUMAN
NC score	0.120918 (rank : 588)	θ value	0.000158464 (rank : 98)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1136	Shared Neighborhood Hits	251
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MLL4_HUMAN
NC score	0.120574 (rank : 589)	θ value	0.00175202 (rank : 184)
Query Neighborhood Hits	1024	Target Neighborhood Hits	722	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SPN90_HUMAN
NC score	0.120460 (rank : 590)	θ value	θ > 10 (rank : 1496)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

C1QA_HUMAN
NC score	0.120447 (rank : 591)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	1024	Target Neighborhood Hits	179	Shared Neighborhood Hits	83
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

SELPL_MOUSE
NC score	0.120191 (rank : 592)	θ value	θ > 10 (rank : 1453)
Query Neighborhood Hits	1024	Target Neighborhood Hits	588	Shared Neighborhood Hits	186
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

TRPV1_MOUSE
NC score	0.120139 (rank : 593)	θ value	θ > 10 (rank : 1534)
Query Neighborhood Hits	1024	Target Neighborhood Hits	189	Shared Neighborhood Hits	142
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

SFTPD_HUMAN
NC score	0.119871 (rank : 594)	θ value	1.38821 (rank : 727)
Query Neighborhood Hits	1024	Target Neighborhood Hits	238	Shared Neighborhood Hits	78
SwissProt Accessions	P35247, Q86YK9, Q9UCJ2, Q9UCJ3	Gene names	SFTPD, PSPD, SFTP4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

TARA_HUMAN
NC score	0.119737 (rank : 595)	θ value	θ > 10 (rank : 1512)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1626	Shared Neighborhood Hits	326
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NOXO1_HUMAN
NC score	0.119574 (rank : 596)	θ value	θ > 10 (rank : 1369)
Query Neighborhood Hits	1024	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

GGN_MOUSE
NC score	0.119219 (rank : 597)	θ value	0.365318 (rank : 558)
Query Neighborhood Hits	1024	Target Neighborhood Hits	311	Shared Neighborhood Hits	117
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PRP5_HUMAN
NC score	0.119113 (rank : 598)	θ value	θ > 10 (rank : 1413)
Query Neighborhood Hits	1024	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

BAG3_MOUSE
NC score	0.118834 (rank : 599)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	1024	Target Neighborhood Hits	513	Shared Neighborhood Hits	217
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

MBB1A_HUMAN
NC score	0.118607 (rank : 600)	θ value	0.62314 (rank : 613)
Query Neighborhood Hits	1024	Target Neighborhood Hits	665	Shared Neighborhood Hits	207
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

ELN_MOUSE
NC score	0.118558 (rank : 601)	θ value	0.813845 (rank : 642)
Query Neighborhood Hits	1024	Target Neighborhood Hits	105	Shared Neighborhood Hits	53
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

DGKK_HUMAN
NC score	0.118505 (rank : 602)	θ value	4.92598e-06 (rank : 56)
Query Neighborhood Hits	1024	Target Neighborhood Hits	378	Shared Neighborhood Hits	101
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

CSF1_HUMAN
NC score	0.118304 (rank : 603)	θ value	θ > 10 (rank : 1152)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	128
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

RSNL2_HUMAN
NC score	0.117931 (rank : 604)	θ value	θ > 10 (rank : 1444)
Query Neighborhood Hits	1024	Target Neighborhood Hits	136	Shared Neighborhood Hits	107
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

BTK_HUMAN
NC score	0.117909 (rank : 605)	θ value	0.0148317 (rank : 303)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1026	Shared Neighborhood Hits	200
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

M3KL4_HUMAN
NC score	0.117531 (rank : 606)	θ value	0.00134147 (rank : 173)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1087	Shared Neighborhood Hits	211
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

SHLB1_MOUSE
NC score	0.117221 (rank : 607)	θ value	0.47712 (rank : 596)
Query Neighborhood Hits	1024	Target Neighborhood Hits	101	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

ZN207_HUMAN
NC score	0.116807 (rank : 608)	θ value	0.125558 (rank : 476)
Query Neighborhood Hits	1024	Target Neighborhood Hits	326	Shared Neighborhood Hits	82
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

SFTPD_MOUSE
NC score	0.116737 (rank : 609)	θ value	0.125558 (rank : 472)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	70
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

ES8L2_MOUSE
NC score	0.116562 (rank : 610)	θ value	θ > 10 (rank : 1218)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	117
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

MKL1_MOUSE
NC score	0.116423 (rank : 611)	θ value	0.813845 (rank : 650)
Query Neighborhood Hits	1024	Target Neighborhood Hits	667	Shared Neighborhood Hits	249
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MARCO_HUMAN
NC score	0.116273 (rank : 612)	θ value	θ > 10 (rank : 1322)
Query Neighborhood Hits	1024	Target Neighborhood Hits	199	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

BLK_HUMAN
NC score	0.116160 (rank : 613)	θ value	0.00134147 (rank : 169)
Query Neighborhood Hits	1024	Target Neighborhood Hits	994	Shared Neighborhood Hits	169
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

SFPQ_MOUSE
NC score	0.116135 (rank : 614)	θ value	0.00134147 (rank : 175)
Query Neighborhood Hits	1024	Target Neighborhood Hits	958	Shared Neighborhood Hits	214
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CBP_HUMAN
NC score	0.115514 (rank : 615)	θ value	4.03905 (rank : 853)
Query Neighborhood Hits	1024	Target Neighborhood Hits	941	Shared Neighborhood Hits	262
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CIC_MOUSE
NC score	0.114637 (rank : 616)	θ value	0.0736092 (rank : 427)
Query Neighborhood Hits	1024	Target Neighborhood Hits	742	Shared Neighborhood Hits	258
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TRPV3_HUMAN
NC score	0.114625 (rank : 617)	θ value	4.03905 (rank : 873)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

RAPH1_HUMAN
NC score	0.114536 (rank : 618)	θ value	6.88961 (rank : 948)
Query Neighborhood Hits	1024	Target Neighborhood Hits	593	Shared Neighborhood Hits	192
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

WASF2_MOUSE
NC score	0.114429 (rank : 619)	θ value	0.0193708 (rank : 338)
Query Neighborhood Hits	1024	Target Neighborhood Hits	315	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

AMPH_HUMAN
NC score	0.114310 (rank : 620)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	159
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

BLK_MOUSE
NC score	0.113995 (rank : 621)	θ value	0.00134147 (rank : 170)
Query Neighborhood Hits	1024	Target Neighborhood Hits	992	Shared Neighborhood Hits	162
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

ADIPO_HUMAN
NC score	0.113726 (rank : 622)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	70
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

T22D4_HUMAN
NC score	0.113544 (rank : 623)	θ value	6.88961 (rank : 957)
Query Neighborhood Hits	1024	Target Neighborhood Hits	403	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

ADIPO_MOUSE
NC score	0.113486 (rank : 624)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	1024	Target Neighborhood Hits	182	Shared Neighborhood Hits	78
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

LYN_HUMAN
NC score	0.112941 (rank : 625)	θ value	0.00102713 (rank : 159)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1022	Shared Neighborhood Hits	179
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

SYN1_HUMAN
NC score	0.112938 (rank : 626)	θ value	0.0330416 (rank : 375)
Query Neighborhood Hits	1024	Target Neighborhood Hits	419	Shared Neighborhood Hits	164
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

PTK6_HUMAN
NC score	0.112588 (rank : 627)	θ value	1.09739e-05 (rank : 64)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1020	Shared Neighborhood Hits	183
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

FRK_HUMAN
NC score	0.112541 (rank : 628)	θ value	0.00869519 (rank : 276)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1058	Shared Neighborhood Hits	198
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

C1QC_MOUSE
NC score	0.112366 (rank : 629)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	1024	Target Neighborhood Hits	150	Shared Neighborhood Hits	68
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

PTK6_MOUSE
NC score	0.112340 (rank : 630)	θ value	4.1701e-05 (rank : 84)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1026	Shared Neighborhood Hits	180
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

WASP_MOUSE
NC score	0.112302 (rank : 631)	θ value	0.00509761 (rank : 251)
Query Neighborhood Hits	1024	Target Neighborhood Hits	223	Shared Neighborhood Hits	99
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

CMTA1_HUMAN
NC score	0.112223 (rank : 632)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

BTK_MOUSE
NC score	0.112075 (rank : 633)	θ value	0.00665767 (rank : 257)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1017	Shared Neighborhood Hits	193
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CO002_HUMAN
NC score	0.111994 (rank : 634)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	1024	Target Neighborhood Hits	387	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

ARI1B_HUMAN
NC score	0.111784 (rank : 635)	θ value	6.88961 (rank : 927)
Query Neighborhood Hits	1024	Target Neighborhood Hits	567	Shared Neighborhood Hits	208
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

SFPQ_HUMAN
NC score	0.111690 (rank : 636)	θ value	0.000461057 (rank : 127)
Query Neighborhood Hits	1024	Target Neighborhood Hits	986	Shared Neighborhood Hits	217
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

MINT_MOUSE
NC score	0.111467 (rank : 637)	θ value	2.36792 (rank : 779)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1514	Shared Neighborhood Hits	311
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

FA47B_HUMAN
NC score	0.111424 (rank : 638)	θ value	θ > 10 (rank : 1223)
Query Neighborhood Hits	1024	Target Neighborhood Hits	431	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

LYN_MOUSE
NC score	0.111347 (rank : 639)	θ value	0.00298849 (rank : 213)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1023	Shared Neighborhood Hits	182
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

CGRE1_HUMAN
NC score	0.111346 (rank : 640)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	1024	Target Neighborhood Hits	354	Shared Neighborhood Hits	122
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

SELV_HUMAN
NC score	0.111134 (rank : 641)	θ value	0.000786445 (rank : 146)
Query Neighborhood Hits	1024	Target Neighborhood Hits	118	Shared Neighborhood Hits	54
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

TRPV1_HUMAN
NC score	0.110621 (rank : 642)	θ value	θ > 10 (rank : 1533)
Query Neighborhood Hits	1024	Target Neighborhood Hits	184	Shared Neighborhood Hits	135
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV3_MOUSE
NC score	0.110528 (rank : 643)	θ value	θ > 10 (rank : 1537)
Query Neighborhood Hits	1024	Target Neighborhood Hits	188	Shared Neighborhood Hits	118
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

RPTN_MOUSE
NC score	0.110148 (rank : 644)	θ value	θ > 10 (rank : 1442)
Query Neighborhood Hits	1024	Target Neighborhood Hits	650	Shared Neighborhood Hits	119
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

M3K9_HUMAN
NC score	0.110145 (rank : 645)	θ value	0.0193708 (rank : 331)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1123	Shared Neighborhood Hits	234
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

SHAN2_MOUSE
NC score	0.110079 (rank : 646)	θ value	θ > 10 (rank : 1467)
Query Neighborhood Hits	1024	Target Neighborhood Hits	446	Shared Neighborhood Hits	169
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SPR1B_MOUSE
NC score	0.108818 (rank : 647)	θ value	θ > 10 (rank : 1499)
Query Neighborhood Hits	1024	Target Neighborhood Hits	395	Shared Neighborhood Hits	162
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

RIMB1_MOUSE
NC score	0.108778 (rank : 648)	θ value	5.27518 (rank : 913)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1376	Shared Neighborhood Hits	274
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

WASF2_HUMAN
NC score	0.108761 (rank : 649)	θ value	0.000602161 (rank : 134)
Query Neighborhood Hits	1024	Target Neighborhood Hits	280	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

SPN90_MOUSE
NC score	0.108577 (rank : 650)	θ value	θ > 10 (rank : 1497)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

GA2L2_MOUSE
NC score	0.108524 (rank : 651)	θ value	0.279714 (rank : 532)
Query Neighborhood Hits	1024	Target Neighborhood Hits	395	Shared Neighborhood Hits	162
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

SYNJ1_MOUSE
NC score	0.108253 (rank : 652)	θ value	0.00509761 (rank : 248)
Query Neighborhood Hits	1024	Target Neighborhood Hits	516	Shared Neighborhood Hits	185
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SHLB1_HUMAN
NC score	0.107859 (rank : 653)	θ value	2.36792 (rank : 787)
Query Neighborhood Hits	1024	Target Neighborhood Hits	96	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

TXND2_HUMAN
NC score	0.107758 (rank : 654)	θ value	θ > 10 (rank : 1546)
Query Neighborhood Hits	1024	Target Neighborhood Hits	793	Shared Neighborhood Hits	171
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CS007_MOUSE
NC score	0.107522 (rank : 655)	θ value	0.0193708 (rank : 328)
Query Neighborhood Hits	1024	Target Neighborhood Hits	464	Shared Neighborhood Hits	154
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

GGN_HUMAN
NC score	0.107369 (rank : 656)	θ value	0.62314 (rank : 609)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	112
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SF3A2_MOUSE
NC score	0.107336 (rank : 657)	θ value	θ > 10 (rank : 1456)
Query Neighborhood Hits	1024	Target Neighborhood Hits	247	Shared Neighborhood Hits	111
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

BIN1_HUMAN
NC score	0.107316 (rank : 658)	θ value	3.0926 (rank : 804)
Query Neighborhood Hits	1024	Target Neighborhood Hits	335	Shared Neighborhood Hits	148
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

C1QT2_HUMAN
NC score	0.106806 (rank : 659)	θ value	2.36792 (rank : 765)
Query Neighborhood Hits	1024	Target Neighborhood Hits	123	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXJ5	Gene names	C1QTNF2, CTRP2
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 2 precursor.

CTHR1_HUMAN
NC score	0.106697 (rank : 660)	θ value	θ > 10 (rank : 1158)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	64
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
NC score	0.106409 (rank : 661)	θ value	θ > 10 (rank : 1159)
Query Neighborhood Hits	1024	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

SPTA1_MOUSE
NC score	0.106129 (rank : 662)	θ value	1.38821 (rank : 730)
Query Neighborhood Hits	1024	Target Neighborhood Hits	675	Shared Neighborhood Hits	160
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

PRG4_HUMAN
NC score	0.105912 (rank : 663)	θ value	θ > 10 (rank : 1411)
Query Neighborhood Hits	1024	Target Neighborhood Hits	764	Shared Neighborhood Hits	168
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRR13_MOUSE
NC score	0.105873 (rank : 664)	θ value	0.279714 (rank : 542)
Query Neighborhood Hits	1024	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

GLDN_HUMAN
NC score	0.105548 (rank : 665)	θ value	θ > 10 (rank : 1244)
Query Neighborhood Hits	1024	Target Neighborhood Hits	159	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

PYGO2_HUMAN
NC score	0.105465 (rank : 666)	θ value	0.00665767 (rank : 266)
Query Neighborhood Hits	1024	Target Neighborhood Hits	189	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

BLNK_MOUSE
NC score	0.105402 (rank : 667)	θ value	1.06291 (rank : 671)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CO6A3_HUMAN
NC score	0.105205 (rank : 668)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	1024	Target Neighborhood Hits	317	Shared Neighborhood Hits	98
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

SF3A2_HUMAN
NC score	0.105095 (rank : 669)	θ value	6.88961 (rank : 952)
Query Neighborhood Hits	1024	Target Neighborhood Hits	263	Shared Neighborhood Hits	104
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

PELP1_HUMAN
NC score	0.104954 (rank : 670)	θ value	0.0252991 (rank : 349)
Query Neighborhood Hits	1024	Target Neighborhood Hits	596	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

FA47A_HUMAN
NC score	0.104799 (rank : 671)	θ value	θ > 10 (rank : 1222)
Query Neighborhood Hits	1024	Target Neighborhood Hits	451	Shared Neighborhood Hits	167
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

TGON2_HUMAN
NC score	0.104616 (rank : 672)	θ value	θ > 10 (rank : 1519)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1037	Shared Neighborhood Hits	222
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RUSC2_MOUSE
NC score	0.103509 (rank : 673)	θ value	2.36792 (rank : 785)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	148
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

DOT1L_HUMAN
NC score	0.103156 (rank : 674)	θ value	θ > 10 (rank : 1171)
Query Neighborhood Hits	1024	Target Neighborhood Hits	660	Shared Neighborhood Hits	166
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

LCK_HUMAN
NC score	0.103117 (rank : 675)	θ value	0.0148317 (rank : 311)
Query Neighborhood Hits	1024	Target Neighborhood Hits	987	Shared Neighborhood Hits	147
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

BASP_MOUSE
NC score	0.103086 (rank : 676)	θ value	0.365318 (rank : 553)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CG1_HUMAN
NC score	0.103034 (rank : 677)	θ value	0.47712 (rank : 577)
Query Neighborhood Hits	1024	Target Neighborhood Hits	222	Shared Neighborhood Hits	101
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

EPS8_MOUSE
NC score	0.102953 (rank : 678)	θ value	θ > 10 (rank : 1212)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	116
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

M3K10_HUMAN
NC score	0.102932 (rank : 679)	θ value	0.0563607 (rank : 414)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1071	Shared Neighborhood Hits	202
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

COEA1_HUMAN
NC score	0.102905 (rank : 680)	θ value	0.813845 (rank : 639)
Query Neighborhood Hits	1024	Target Neighborhood Hits	427	Shared Neighborhood Hits	114
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CS016_HUMAN
NC score	0.102777 (rank : 681)	θ value	θ > 10 (rank : 1149)
Query Neighborhood Hits	1024	Target Neighborhood Hits	310	Shared Neighborhood Hits	111
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

LCK_MOUSE
NC score	0.102428 (rank : 682)	θ value	0.0148317 (rank : 312)
Query Neighborhood Hits	1024	Target Neighborhood Hits	981	Shared Neighborhood Hits	144
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

C1QB_MOUSE
NC score	0.102428 (rank : 683)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	62
SwissProt Accessions	P14106	Gene names	C1qb
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

MILK1_MOUSE
NC score	0.101988 (rank : 684)	θ value	θ > 10 (rank : 1337)
Query Neighborhood Hits	1024	Target Neighborhood Hits	788	Shared Neighborhood Hits	262
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

K1802_HUMAN
NC score	0.101813 (rank : 685)	θ value	0.0148317 (rank : 310)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1378	Shared Neighborhood Hits	288
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CN155_HUMAN
NC score	0.101636 (rank : 686)	θ value	3.0926 (rank : 807)
Query Neighborhood Hits	1024	Target Neighborhood Hits	385	Shared Neighborhood Hits	110
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

C1QC_HUMAN
NC score	0.101511 (rank : 687)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	1024	Target Neighborhood Hits	124	Shared Neighborhood Hits	59
SwissProt Accessions	P02747, Q7Z502, Q96DL2, Q96H05	Gene names	C1QC, C1QG
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

TAU_MOUSE
NC score	0.101499 (rank : 688)	θ value	θ > 10 (rank : 1514)
Query Neighborhood Hits	1024	Target Neighborhood Hits	502	Shared Neighborhood Hits	184
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

SPTA1_HUMAN
NC score	0.101239 (rank : 689)	θ value	θ > 10 (rank : 1501)
Query Neighborhood Hits	1024	Target Neighborhood Hits	748	Shared Neighborhood Hits	175
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

GLDN_MOUSE
NC score	0.101189 (rank : 690)	θ value	θ > 10 (rank : 1245)
Query Neighborhood Hits	1024	Target Neighborhood Hits	155	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

CASC3_MOUSE
NC score	0.100872 (rank : 691)	θ value	0.0193708 (rank : 324)
Query Neighborhood Hits	1024	Target Neighborhood Hits	333	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

RSNL2_MOUSE
NC score	0.100839 (rank : 692)	θ value	θ > 10 (rank : 1445)
Query Neighborhood Hits	1024	Target Neighborhood Hits	129	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

BIM_HUMAN
NC score	0.100747 (rank : 693)	θ value	4.03905 (rank : 851)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	84
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

PRR13_HUMAN
NC score	0.100645 (rank : 694)	θ value	0.47712 (rank : 593)
Query Neighborhood Hits	1024	Target Neighborhood Hits	105	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

MSRE_HUMAN
NC score	0.100619 (rank : 695)	θ value	θ > 10 (rank : 1348)
Query Neighborhood Hits	1024	Target Neighborhood Hits	298	Shared Neighborhood Hits	74
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

C1QT7_MOUSE
NC score	0.100534 (rank : 696)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	1024	Target Neighborhood Hits	124	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BVD7, Q8CHX9	Gene names	C1qtnf7, Ctrp7
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

MTSS1_HUMAN
NC score	0.100435 (rank : 697)	θ value	θ > 10 (rank : 1350)
Query Neighborhood Hits	1024	Target Neighborhood Hits	504	Shared Neighborhood Hits	166
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

TEC_HUMAN
NC score	0.100269 (rank : 698)	θ value	0.00509761 (rank : 250)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1006	Shared Neighborhood Hits	170
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

C1QB_HUMAN
NC score	0.099407 (rank : 699)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	1024	Target Neighborhood Hits	126	Shared Neighborhood Hits	58
SwissProt Accessions	P02746, Q5T959, Q96H17	Gene names	C1QB
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

EPS8_HUMAN
NC score	0.099311 (rank : 700)	θ value	θ > 10 (rank : 1211)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	109
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

SYNJ1_HUMAN
NC score	0.098832 (rank : 701)	θ value	0.000602161 (rank : 133)
Query Neighborhood Hits	1024	Target Neighborhood Hits	498	Shared Neighborhood Hits	170
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CMTA2_MOUSE
NC score	0.098465 (rank : 702)	θ value	0.62314 (rank : 607)
Query Neighborhood Hits	1024	Target Neighborhood Hits	216	Shared Neighborhood Hits	103
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

C1QT7_HUMAN
NC score	0.098147 (rank : 703)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	1024	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXJ2	Gene names	C1QTNF7, CTRP7
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

GA2L1_HUMAN
NC score	0.097885 (rank : 704)	θ value	0.00102713 (rank : 155)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

BIM_MOUSE
NC score	0.097707 (rank : 705)	θ value	4.03905 (rank : 852)
Query Neighborhood Hits	1024	Target Neighborhood Hits	124	Shared Neighborhood Hits	78
SwissProt Accessions	O54918, O54919, O54920	Gene names	Bcl2l11, Bim
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

CRSP7_HUMAN
NC score	0.097691 (rank : 706)	θ value	θ > 10 (rank : 1146)
Query Neighborhood Hits	1024	Target Neighborhood Hits	247	Shared Neighborhood Hits	112
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

AATK_HUMAN
NC score	0.097671 (rank : 707)	θ value	0.163984 (rank : 477)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1243	Shared Neighborhood Hits	284
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ABL1_MOUSE
NC score	0.097637 (rank : 708)	θ value	5.27518 (rank : 877)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1178	Shared Neighborhood Hits	223
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

TEC_MOUSE
NC score	0.097602 (rank : 709)	θ value	0.0330416 (rank : 376)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1006	Shared Neighborhood Hits	169
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

PRPC_HUMAN
NC score	0.097573 (rank : 710)	θ value	2.36792 (rank : 783)
Query Neighborhood Hits	1024	Target Neighborhood Hits	165	Shared Neighborhood Hits	74
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

C1QT5_HUMAN
NC score	0.097316 (rank : 711)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	1024	Target Neighborhood Hits	137	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BXJ0, Q8N6P2, Q9UFX4	Gene names	C1QTNF5, CTRP5
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

ABL1_HUMAN
NC score	0.096958 (rank : 712)	θ value	5.27518 (rank : 876)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1220	Shared Neighborhood Hits	235
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

C1QA_MOUSE
NC score	0.096678 (rank : 713)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	1024	Target Neighborhood Hits	116	Shared Neighborhood Hits	54
SwissProt Accessions	P98086	Gene names	C1qa
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

COKA1_HUMAN
NC score	0.096667 (rank : 714)	θ value	1.38821 (rank : 709)
Query Neighborhood Hits	1024	Target Neighborhood Hits	403	Shared Neighborhood Hits	126
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CMTA2_HUMAN
NC score	0.096610 (rank : 715)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	1024	Target Neighborhood Hits	199	Shared Neighborhood Hits	105
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

ELN_HUMAN
NC score	0.096416 (rank : 716)	θ value	θ > 10 (rank : 1176)
Query Neighborhood Hits	1024	Target Neighborhood Hits	85	Shared Neighborhood Hits	39
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

TRPV2_HUMAN
NC score	0.096245 (rank : 717)	θ value	θ > 10 (rank : 1535)
Query Neighborhood Hits	1024	Target Neighborhood Hits	130	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

SGIP1_MOUSE
NC score	0.095728 (rank : 718)	θ value	0.0736092 (rank : 438)
Query Neighborhood Hits	1024	Target Neighborhood Hits	180	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

WASP_HUMAN
NC score	0.095235 (rank : 719)	θ value	0.0431538 (rank : 393)
Query Neighborhood Hits	1024	Target Neighborhood Hits	195	Shared Neighborhood Hits	91
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

SGIP1_HUMAN
NC score	0.095077 (rank : 720)	θ value	0.0961366 (rank : 455)
Query Neighborhood Hits	1024	Target Neighborhood Hits	198	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYN1_MOUSE
NC score	0.094882 (rank : 721)	θ value	0.62314 (rank : 621)
Query Neighborhood Hits	1024	Target Neighborhood Hits	363	Shared Neighborhood Hits	142
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

C1QT5_MOUSE
NC score	0.094711 (rank : 722)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	1024	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

ITK_HUMAN
NC score	0.094506 (rank : 723)	θ value	0.0736092 (rank : 430)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1016	Shared Neighborhood Hits	164
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

NU214_HUMAN
NC score	0.094490 (rank : 724)	θ value	1.06291 (rank : 695)
Query Neighborhood Hits	1024	Target Neighborhood Hits	657	Shared Neighborhood Hits	148
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

WASF4_HUMAN
NC score	0.094473 (rank : 725)	θ value	0.62314 (rank : 627)
Query Neighborhood Hits	1024	Target Neighborhood Hits	282	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

NRX2A_HUMAN
NC score	0.094423 (rank : 726)	θ value	θ > 10 (rank : 1372)
Query Neighborhood Hits	1024	Target Neighborhood Hits	614	Shared Neighborhood Hits	255
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

CJ078_MOUSE
NC score	0.094378 (rank : 727)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	1024	Target Neighborhood Hits	559	Shared Neighborhood Hits	130
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

TXK_MOUSE
NC score	0.094008 (rank : 728)	θ value	θ > 10 (rank : 1544)
Query Neighborhood Hits	1024	Target Neighborhood Hits	980	Shared Neighborhood Hits	161
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

S23IP_MOUSE
NC score	0.093775 (rank : 729)	θ value	θ > 10 (rank : 1450)
Query Neighborhood Hits	1024	Target Neighborhood Hits	363	Shared Neighborhood Hits	154
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

PHC2_HUMAN
NC score	0.093331 (rank : 730)	θ value	1.38821 (rank : 722)
Query Neighborhood Hits	1024	Target Neighborhood Hits	388	Shared Neighborhood Hits	156
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

MAP1A_HUMAN
NC score	0.093208 (rank : 731)	θ value	0.163984 (rank : 488)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1626	Shared Neighborhood Hits	291
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PI5PA_MOUSE
NC score	0.093118 (rank : 732)	θ value	0.0961366 (rank : 453)
Query Neighborhood Hits	1024	Target Neighborhood Hits	331	Shared Neighborhood Hits	129
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

GNAS1_MOUSE
NC score	0.093045 (rank : 733)	θ value	1.38821 (rank : 714)
Query Neighborhood Hits	1024	Target Neighborhood Hits	651	Shared Neighborhood Hits	252
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

SYP2L_HUMAN
NC score	0.092920 (rank : 734)	θ value	0.00509761 (rank : 249)
Query Neighborhood Hits	1024	Target Neighborhood Hits	400	Shared Neighborhood Hits	125
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CIP4_HUMAN
NC score	0.092054 (rank : 735)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	1024	Target Neighborhood Hits	374	Shared Neighborhood Hits	78
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

AMPH_MOUSE
NC score	0.091858 (rank : 736)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	105
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

CABIN_HUMAN
NC score	0.091205 (rank : 737)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	1024	Target Neighborhood Hits	490	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

C1QRF_HUMAN
NC score	0.091154 (rank : 738)	θ value	3.0926 (rank : 805)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	66
SwissProt Accessions	O75973	Gene names	C1QL1, C1QRF, CRF
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

C1QT1_HUMAN
NC score	0.090762 (rank : 739)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	1024	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BXJ1, Q96NF2, Q9GZR4	Gene names	C1QTNF1, CTRP1
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 1 precursor (G protein-coupled receptor-interacting protein) (GIP).

TXK_HUMAN
NC score	0.090653 (rank : 740)	θ value	θ > 10 (rank : 1543)
Query Neighborhood Hits	1024	Target Neighborhood Hits	971	Shared Neighborhood Hits	155
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

CIZ1_HUMAN
NC score	0.090236 (rank : 741)	θ value	0.47712 (rank : 578)
Query Neighborhood Hits	1024	Target Neighborhood Hits	359	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

SPR1A_MOUSE
NC score	0.089657 (rank : 742)	θ value	θ > 10 (rank : 1498)
Query Neighborhood Hits	1024	Target Neighborhood Hits	343	Shared Neighborhood Hits	142
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

K0310_HUMAN
NC score	0.089453 (rank : 743)	θ value	θ > 10 (rank : 1290)
Query Neighborhood Hits	1024	Target Neighborhood Hits	420	Shared Neighborhood Hits	163
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

CNOT3_MOUSE
NC score	0.089373 (rank : 744)	θ value	0.21417 (rank : 503)
Query Neighborhood Hits	1024	Target Neighborhood Hits	504	Shared Neighborhood Hits	120
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

HRBL_MOUSE
NC score	0.089312 (rank : 745)	θ value	θ > 10 (rank : 1263)
Query Neighborhood Hits	1024	Target Neighborhood Hits	269	Shared Neighborhood Hits	127
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

SH21B_MOUSE
NC score	0.089224 (rank : 746)	θ value	θ > 10 (rank : 1465)
Query Neighborhood Hits	1024	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

BIN1_MOUSE
NC score	0.088562 (rank : 747)	θ value	0.813845 (rank : 634)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	122
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

PRPE_HUMAN
NC score	0.088538 (rank : 748)	θ value	θ > 10 (rank : 1414)
Query Neighborhood Hits	1024	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

RPB1_MOUSE
NC score	0.088486 (rank : 749)	θ value	0.279714 (rank : 546)
Query Neighborhood Hits	1024	Target Neighborhood Hits	363	Shared Neighborhood Hits	108
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.088443 (rank : 750)	θ value	0.279714 (rank : 545)
Query Neighborhood Hits	1024	Target Neighborhood Hits	362	Shared Neighborhood Hits	107
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CSK_HUMAN
NC score	0.088030 (rank : 751)	θ value	θ > 10 (rank : 1153)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1009	Shared Neighborhood Hits	167
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

3BP1_HUMAN
NC score	0.087928 (rank : 752)	θ value	0.125558 (rank : 459)
Query Neighborhood Hits	1024	Target Neighborhood Hits	376	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

PCQAP_HUMAN
NC score	0.087926 (rank : 753)	θ value	θ > 10 (rank : 1392)
Query Neighborhood Hits	1024	Target Neighborhood Hits	549	Shared Neighborhood Hits	127
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

CSK_MOUSE
NC score	0.087859 (rank : 754)	θ value	θ > 10 (rank : 1154)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1009	Shared Neighborhood Hits	167
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

SFR15_HUMAN
NC score	0.087766 (rank : 755)	θ value	0.813845 (rank : 658)
Query Neighborhood Hits	1024	Target Neighborhood Hits	368	Shared Neighborhood Hits	113
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

ABL2_HUMAN
NC score	0.087740 (rank : 756)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1045	Shared Neighborhood Hits	166
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ITK_MOUSE
NC score	0.087662 (rank : 757)	θ value	2.36792 (rank : 777)
Query Neighborhood Hits	1024	Target Neighborhood Hits	985	Shared Neighborhood Hits	152
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

C1QRF_MOUSE
NC score	0.087460 (rank : 758)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	1024	Target Neighborhood Hits	140	Shared Neighborhood Hits	63
SwissProt Accessions	O88992	Gene names	C1ql1, C1qrf, Crf
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

C1QL3_MOUSE
NC score	0.086828 (rank : 759)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	1024	Target Neighborhood Hits	127	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ESN4	Gene names	C1ql3, C1ql
Domain Architecture
Description	Complement C1q-like protein 3 precursor (Gliacolin).

SFTPA_MOUSE
NC score	0.086587 (rank : 760)	θ value	θ > 10 (rank : 1461)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	54
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

STS2_HUMAN
NC score	0.086504 (rank : 761)	θ value	4.03905 (rank : 868)
Query Neighborhood Hits	1024	Target Neighborhood Hits	108	Shared Neighborhood Hits	73
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

CS007_HUMAN
NC score	0.086314 (rank : 762)	θ value	0.0252991 (rank : 345)
Query Neighborhood Hits	1024	Target Neighborhood Hits	401	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

P85A_MOUSE
NC score	0.086147 (rank : 763)	θ value	θ > 10 (rank : 1388)
Query Neighborhood Hits	1024	Target Neighborhood Hits	435	Shared Neighborhood Hits	120
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CRTC1_HUMAN
NC score	0.086092 (rank : 764)	θ value	θ > 10 (rank : 1147)
Query Neighborhood Hits	1024	Target Neighborhood Hits	319	Shared Neighborhood Hits	150
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

SHLB2_MOUSE
NC score	0.085813 (rank : 765)	θ value	θ > 10 (rank : 1481)
Query Neighborhood Hits	1024	Target Neighborhood Hits	88	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

PGCA_HUMAN
NC score	0.085589 (rank : 766)	θ value	θ > 10 (rank : 1397)
Query Neighborhood Hits	1024	Target Neighborhood Hits	821	Shared Neighborhood Hits	143
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

IWS1_MOUSE
NC score	0.085583 (rank : 767)	θ value	θ > 10 (rank : 1285)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1258	Shared Neighborhood Hits	218
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

FMN2_HUMAN
NC score	0.085432 (rank : 768)	θ value	0.0330416 (rank : 365)
Query Neighborhood Hits	1024	Target Neighborhood Hits	484	Shared Neighborhood Hits	133
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

SC24A_MOUSE
NC score	0.085408 (rank : 769)	θ value	θ > 10 (rank : 1452)
Query Neighborhood Hits	1024	Target Neighborhood Hits	394	Shared Neighborhood Hits	178
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

RASA1_HUMAN
NC score	0.085227 (rank : 770)	θ value	θ > 10 (rank : 1418)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	69
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

PRG4_MOUSE
NC score	0.084962 (rank : 771)	θ value	θ > 10 (rank : 1412)
Query Neighborhood Hits	1024	Target Neighborhood Hits	624	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SHLB2_HUMAN
NC score	0.084790 (rank : 772)	θ value	θ > 10 (rank : 1480)
Query Neighborhood Hits	1024	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

TARA_MOUSE
NC score	0.084617 (rank : 773)	θ value	θ > 10 (rank : 1513)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1133	Shared Neighborhood Hits	212
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

K1543_MOUSE
NC score	0.084434 (rank : 774)	θ value	θ > 10 (rank : 1292)
Query Neighborhood Hits	1024	Target Neighborhood Hits	497	Shared Neighborhood Hits	178
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

FMNL_HUMAN
NC score	0.084431 (rank : 775)	θ value	0.163984 (rank : 484)
Query Neighborhood Hits	1024	Target Neighborhood Hits	529	Shared Neighborhood Hits	146
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

MNT_HUMAN
NC score	0.084386 (rank : 776)	θ value	θ > 10 (rank : 1344)
Query Neighborhood Hits	1024	Target Neighborhood Hits	496	Shared Neighborhood Hits	157
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SRMS_MOUSE
NC score	0.084373 (rank : 777)	θ value	θ > 10 (rank : 1504)
Query Neighborhood Hits	1024	Target Neighborhood Hits	964	Shared Neighborhood Hits	136
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

COEA1_MOUSE
NC score	0.084166 (rank : 778)	θ value	θ > 10 (rank : 1139)
Query Neighborhood Hits	1024	Target Neighborhood Hits	402	Shared Neighborhood Hits	108
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

C1QT3_MOUSE
NC score	0.084109 (rank : 779)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	1024	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ES30	Gene names	C1qtnf3, Cors26, Ctrp3
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 3 precursor (Secretory protein CORS26).

PO121_MOUSE
NC score	0.084075 (rank : 780)	θ value	0.813845 (rank : 654)
Query Neighborhood Hits	1024	Target Neighborhood Hits	345	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

MSRE_MOUSE
NC score	0.084066 (rank : 781)	θ value	θ > 10 (rank : 1349)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	73
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

ZIMP7_HUMAN
NC score	0.084037 (rank : 782)	θ value	θ > 10 (rank : 1563)
Query Neighborhood Hits	1024	Target Neighborhood Hits	290	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

GAK5_HUMAN
NC score	0.084023 (rank : 783)	θ value	0.21417 (rank : 505)
Query Neighborhood Hits	1024	Target Neighborhood Hits	429	Shared Neighborhood Hits	186
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SH21B_HUMAN
NC score	0.083547 (rank : 784)	θ value	θ > 10 (rank : 1464)
Query Neighborhood Hits	1024	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

PKHA4_HUMAN
NC score	0.083272 (rank : 785)	θ value	0.0431538 (rank : 390)
Query Neighborhood Hits	1024	Target Neighborhood Hits	283	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

C1QT3_HUMAN
NC score	0.083068 (rank : 786)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	1024	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXJ4, Q6MZN1, Q96KY1	Gene names	C1QTNF3, CTRP3
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 3 precursor (Secretory protein CORS26).

T22D2_HUMAN
NC score	0.082898 (rank : 787)	θ value	0.62314 (rank : 623)
Query Neighborhood Hits	1024	Target Neighborhood Hits	250	Shared Neighborhood Hits	98
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

R3HD2_MOUSE
NC score	0.082574 (rank : 788)	θ value	8.99809 (rank : 1007)
Query Neighborhood Hits	1024	Target Neighborhood Hits	397	Shared Neighborhood Hits	151
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

WDR33_HUMAN
NC score	0.082221 (rank : 789)	θ value	0.365318 (rank : 572)
Query Neighborhood Hits	1024	Target Neighborhood Hits	638	Shared Neighborhood Hits	156
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

DAPP1_HUMAN
NC score	0.082128 (rank : 790)	θ value	θ > 10 (rank : 1162)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

P85A_HUMAN
NC score	0.082104 (rank : 791)	θ value	θ > 10 (rank : 1387)
Query Neighborhood Hits	1024	Target Neighborhood Hits	479	Shared Neighborhood Hits	117
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

WASF1_MOUSE
NC score	0.081513 (rank : 792)	θ value	θ > 10 (rank : 1556)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	102
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

SNX9_HUMAN
NC score	0.081476 (rank : 793)	θ value	θ > 10 (rank : 1492)
Query Neighborhood Hits	1024	Target Neighborhood Hits	148	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SF01_HUMAN
NC score	0.081373 (rank : 794)	θ value	1.38821 (rank : 726)
Query Neighborhood Hits	1024	Target Neighborhood Hits	287	Shared Neighborhood Hits	115
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

ACK1_MOUSE
NC score	0.081185 (rank : 795)	θ value	4.03905 (rank : 845)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1080	Shared Neighborhood Hits	220
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

TROAP_HUMAN
NC score	0.081086 (rank : 796)	θ value	θ > 10 (rank : 1532)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	109
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

RUSC2_HUMAN
NC score	0.080867 (rank : 797)	θ value	θ > 10 (rank : 1447)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

DAPP1_MOUSE
NC score	0.080730 (rank : 798)	θ value	θ > 10 (rank : 1163)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

ACK1_HUMAN
NC score	0.080615 (rank : 799)	θ value	8.99809 (rank : 967)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1140	Shared Neighborhood Hits	232
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ZN645_HUMAN
NC score	0.080563 (rank : 800)	θ value	θ > 10 (rank : 1566)
Query Neighborhood Hits	1024	Target Neighborhood Hits	265	Shared Neighborhood Hits	98
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

MAML3_HUMAN
NC score	0.080414 (rank : 801)	θ value	θ > 10 (rank : 1320)
Query Neighborhood Hits	1024	Target Neighborhood Hits	323	Shared Neighborhood Hits	115
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

SRMS_HUMAN
NC score	0.080368 (rank : 802)	θ value	θ > 10 (rank : 1503)
Query Neighborhood Hits	1024	Target Neighborhood Hits	946	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

GAK11_HUMAN
NC score	0.080333 (rank : 803)	θ value	1.06291 (rank : 679)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	177
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

C1QT6_HUMAN
NC score	0.080330 (rank : 804)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	1024	Target Neighborhood Hits	122	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXI9	Gene names	C1QTNF6, CTRP6
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 6 precursor.

GAK4_HUMAN
NC score	0.080328 (rank : 805)	θ value	1.06291 (rank : 683)
Query Neighborhood Hits	1024	Target Neighborhood Hits	415	Shared Neighborhood Hits	179
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SFTA2_HUMAN
NC score	0.080273 (rank : 806)	θ value	θ > 10 (rank : 1460)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IWL1, P07714, Q5RIR8, Q5RIR9	Gene names	SFTPA2, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A2 precursor (SP-A2) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

SRBP1_MOUSE
NC score	0.080224 (rank : 807)	θ value	θ > 10 (rank : 1502)
Query Neighborhood Hits	1024	Target Neighborhood Hits	384	Shared Neighborhood Hits	137
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

GAK2_HUMAN
NC score	0.080165 (rank : 808)	θ value	1.06291 (rank : 682)
Query Neighborhood Hits	1024	Target Neighborhood Hits	406	Shared Neighborhood Hits	177
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

BAZ2A_MOUSE
NC score	0.080151 (rank : 809)	θ value	1.06291 (rank : 670)
Query Neighborhood Hits	1024	Target Neighborhood Hits	744	Shared Neighborhood Hits	193
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

SEPT9_HUMAN
NC score	0.079702 (rank : 810)	θ value	1.38821 (rank : 725)
Query Neighborhood Hits	1024	Target Neighborhood Hits	706	Shared Neighborhood Hits	222
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

NGEF_MOUSE
NC score	0.079563 (rank : 811)	θ value	θ > 10 (rank : 1367)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

GAK6_HUMAN
NC score	0.079467 (rank : 812)	θ value	0.813845 (rank : 644)
Query Neighborhood Hits	1024	Target Neighborhood Hits	392	Shared Neighborhood Hits	170
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SFTA1_HUMAN
NC score	0.079391 (rank : 813)	θ value	θ > 10 (rank : 1459)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IWL2, P07714, Q5RIR5, Q5RIR7, Q6PIT0, Q8TC19	Gene names	SFTPA1, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A1 precursor (SP-A1) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

WASF1_HUMAN
NC score	0.079388 (rank : 814)	θ value	θ > 10 (rank : 1555)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	106
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

NUMBL_HUMAN
NC score	0.079265 (rank : 815)	θ value	θ > 10 (rank : 1381)
Query Neighborhood Hits	1024	Target Neighborhood Hits	394	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

TB182_HUMAN
NC score	0.079164 (rank : 816)	θ value	θ > 10 (rank : 1515)
Query Neighborhood Hits	1024	Target Neighborhood Hits	414	Shared Neighborhood Hits	139
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

CASC3_HUMAN
NC score	0.078681 (rank : 817)	θ value	0.00509761 (rank : 233)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	45
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

VASP_HUMAN
NC score	0.078450 (rank : 818)	θ value	0.47712 (rank : 600)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	92
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

PKHA6_HUMAN
NC score	0.078449 (rank : 819)	θ value	θ > 10 (rank : 1403)
Query Neighborhood Hits	1024	Target Neighborhood Hits	556	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

LRRK1_MOUSE
NC score	0.078357 (rank : 820)	θ value	θ > 10 (rank : 1311)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1267	Shared Neighborhood Hits	179
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

FGD1_MOUSE
NC score	0.077872 (rank : 821)	θ value	8.99809 (rank : 986)
Query Neighborhood Hits	1024	Target Neighborhood Hits	387	Shared Neighborhood Hits	154
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ATX2_MOUSE
NC score	0.077860 (rank : 822)	θ value	8.99809 (rank : 976)
Query Neighborhood Hits	1024	Target Neighborhood Hits	445	Shared Neighborhood Hits	146
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

K1543_HUMAN
NC score	0.077792 (rank : 823)	θ value	θ > 10 (rank : 1291)
Query Neighborhood Hits	1024	Target Neighborhood Hits	435	Shared Neighborhood Hits	170
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

RTP3_MOUSE
NC score	0.077610 (rank : 824)	θ value	θ > 10 (rank : 1446)
Query Neighborhood Hits	1024	Target Neighborhood Hits	374	Shared Neighborhood Hits	139
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

EMIL1_HUMAN
NC score	0.077573 (rank : 825)	θ value	θ > 10 (rank : 1177)
Query Neighborhood Hits	1024	Target Neighborhood Hits	239	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

EMIL2_MOUSE
NC score	0.077373 (rank : 826)	θ value	θ > 10 (rank : 1180)
Query Neighborhood Hits	1024	Target Neighborhood Hits	485	Shared Neighborhood Hits	112
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

SYP2L_MOUSE
NC score	0.077273 (rank : 827)	θ value	0.00228821 (rank : 200)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ARHG5_HUMAN
NC score	0.077271 (rank : 828)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	1024	Target Neighborhood Hits	172	Shared Neighborhood Hits	81
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

BRD4_MOUSE
NC score	0.077134 (rank : 829)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	1024	Target Neighborhood Hits	845	Shared Neighborhood Hits	185
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

AKAP2_HUMAN
NC score	0.077032 (rank : 830)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	1024	Target Neighborhood Hits	507	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

TS13_MOUSE
NC score	0.076688 (rank : 831)	θ value	θ > 10 (rank : 1541)
Query Neighborhood Hits	1024	Target Neighborhood Hits	191	Shared Neighborhood Hits	95
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

MUC1_MOUSE
NC score	0.076411 (rank : 832)	θ value	θ > 10 (rank : 1352)
Query Neighborhood Hits	1024	Target Neighborhood Hits	388	Shared Neighborhood Hits	78
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

EMIL1_MOUSE
NC score	0.076240 (rank : 833)	θ value	θ > 10 (rank : 1178)
Query Neighborhood Hits	1024	Target Neighborhood Hits	214	Shared Neighborhood Hits	70
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

MAML1_MOUSE
NC score	0.076239 (rank : 834)	θ value	1.38821 (rank : 716)
Query Neighborhood Hits	1024	Target Neighborhood Hits	279	Shared Neighborhood Hits	119
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

CO039_HUMAN
NC score	0.076126 (rank : 835)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	110
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

IL3B2_MOUSE
NC score	0.076126 (rank : 836)	θ value	θ > 10 (rank : 1271)
Query Neighborhood Hits	1024	Target Neighborhood Hits	372	Shared Neighborhood Hits	170
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

PKHG1_HUMAN
NC score	0.076052 (rank : 837)	θ value	θ > 10 (rank : 1405)
Query Neighborhood Hits	1024	Target Neighborhood Hits	174	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ARHG1_MOUSE
NC score	0.075896 (rank : 838)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	1024	Target Neighborhood Hits	266	Shared Neighborhood Hits	114
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

COCA1_MOUSE
NC score	0.075812 (rank : 839)	θ value	3.0926 (rank : 808)
Query Neighborhood Hits	1024	Target Neighborhood Hits	467	Shared Neighborhood Hits	114
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MYO15_HUMAN
NC score	0.075680 (rank : 840)	θ value	0.163984 (rank : 489)
Query Neighborhood Hits	1024	Target Neighborhood Hits	671	Shared Neighborhood Hits	261
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOR2_HUMAN
NC score	0.075607 (rank : 841)	θ value	θ > 10 (rank : 1362)
Query Neighborhood Hits	1024	Target Neighborhood Hits	870	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SYNPO_HUMAN
NC score	0.075067 (rank : 842)	θ value	0.62314 (rank : 622)
Query Neighborhood Hits	1024	Target Neighborhood Hits	281	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

IF4G1_MOUSE
NC score	0.075041 (rank : 843)	θ value	θ > 10 (rank : 1266)
Query Neighborhood Hits	1024	Target Neighborhood Hits	534	Shared Neighborhood Hits	187
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

ATX7_MOUSE
NC score	0.074824 (rank : 844)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	1024	Target Neighborhood Hits	328	Shared Neighborhood Hits	151
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

IWS1_HUMAN
NC score	0.074823 (rank : 845)	θ value	θ > 10 (rank : 1284)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1241	Shared Neighborhood Hits	200
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MEGF9_MOUSE
NC score	0.074763 (rank : 846)	θ value	2.36792 (rank : 778)
Query Neighborhood Hits	1024	Target Neighborhood Hits	896	Shared Neighborhood Hits	224
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NGEF_HUMAN
NC score	0.074714 (rank : 847)	θ value	θ > 10 (rank : 1366)
Query Neighborhood Hits	1024	Target Neighborhood Hits	166	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PKHA4_MOUSE
NC score	0.074514 (rank : 848)	θ value	0.00175202 (rank : 185)
Query Neighborhood Hits	1024	Target Neighborhood Hits	202	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PER3_HUMAN
NC score	0.074483 (rank : 849)	θ value	θ > 10 (rank : 1396)
Query Neighborhood Hits	1024	Target Neighborhood Hits	479	Shared Neighborhood Hits	184
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

FGD1_HUMAN
NC score	0.074435 (rank : 850)	θ value	1.06291 (rank : 678)
Query Neighborhood Hits	1024	Target Neighborhood Hits	367	Shared Neighborhood Hits	129
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

CNOT3_HUMAN
NC score	0.074337 (rank : 851)	θ value	1.38821 (rank : 708)
Query Neighborhood Hits	1024	Target Neighborhood Hits	425	Shared Neighborhood Hits	89
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

RP3A_MOUSE
NC score	0.074302 (rank : 852)	θ value	6.88961 (rank : 949)
Query Neighborhood Hits	1024	Target Neighborhood Hits	510	Shared Neighborhood Hits	194
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

MATK_HUMAN
NC score	0.074148 (rank : 853)	θ value	θ > 10 (rank : 1324)
Query Neighborhood Hits	1024	Target Neighborhood Hits	954	Shared Neighborhood Hits	115
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
NC score	0.074109 (rank : 854)	θ value	8.99809 (rank : 999)
Query Neighborhood Hits	1024	Target Neighborhood Hits	952	Shared Neighborhood Hits	117
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

GAK12_HUMAN
NC score	0.073986 (rank : 855)	θ value	1.06291 (rank : 680)
Query Neighborhood Hits	1024	Target Neighborhood Hits	374	Shared Neighborhood Hits	165
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ENAH_HUMAN
NC score	0.073910 (rank : 856)	θ value	8.99809 (rank : 985)
Query Neighborhood Hits	1024	Target Neighborhood Hits	784	Shared Neighborhood Hits	131
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

HRX_HUMAN
NC score	0.073758 (rank : 857)	θ value	θ > 10 (rank : 1264)
Query Neighborhood Hits	1024	Target Neighborhood Hits	825	Shared Neighborhood Hits	157
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

COCA1_HUMAN
NC score	0.073748 (rank : 858)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	1024	Target Neighborhood Hits	458	Shared Neighborhood Hits	103
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

LAD1_MOUSE
NC score	0.073690 (rank : 859)	θ value	θ > 10 (rank : 1303)
Query Neighborhood Hits	1024	Target Neighborhood Hits	391	Shared Neighborhood Hits	99
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

PKHG4_HUMAN
NC score	0.073626 (rank : 860)	θ value	θ > 10 (rank : 1406)
Query Neighborhood Hits	1024	Target Neighborhood Hits	200	Shared Neighborhood Hits	91
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

JADE2_MOUSE
NC score	0.073222 (rank : 861)	θ value	θ > 10 (rank : 1286)
Query Neighborhood Hits	1024	Target Neighborhood Hits	560	Shared Neighborhood Hits	203
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PKHA6_MOUSE
NC score	0.073130 (rank : 862)	θ value	θ > 10 (rank : 1404)
Query Neighborhood Hits	1024	Target Neighborhood Hits	591	Shared Neighborhood Hits	162
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MCF2L_MOUSE
NC score	0.073124 (rank : 863)	θ value	θ > 10 (rank : 1330)
Query Neighborhood Hits	1024	Target Neighborhood Hits	255	Shared Neighborhood Hits	54
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

NIPBL_HUMAN
NC score	0.073090 (rank : 864)	θ value	8.99809 (rank : 1001)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1311	Shared Neighborhood Hits	187
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PDZD2_HUMAN
NC score	0.073084 (rank : 865)	θ value	θ > 10 (rank : 1394)
Query Neighborhood Hits	1024	Target Neighborhood Hits	772	Shared Neighborhood Hits	192
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

MINT_HUMAN
NC score	0.073068 (rank : 866)	θ value	4.03905 (rank : 861)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1291	Shared Neighborhood Hits	229
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

P85B_HUMAN
NC score	0.072882 (rank : 867)	θ value	θ > 10 (rank : 1389)
Query Neighborhood Hits	1024	Target Neighborhood Hits	543	Shared Neighborhood Hits	107
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

VASP_MOUSE
NC score	0.072551 (rank : 868)	θ value	0.163984 (rank : 494)
Query Neighborhood Hits	1024	Target Neighborhood Hits	195	Shared Neighborhood Hits	73
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

MBL2_HUMAN
NC score	0.072535 (rank : 869)	θ value	θ > 10 (rank : 1328)
Query Neighborhood Hits	1024	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	P11226, Q86SI4, Q96KE4, Q96TF7, Q96TF8, Q96TF9	Gene names	MBL2, MBL
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (MBP1) (Mannan-binding protein) (Mannose-binding lectin).

PHLB1_HUMAN
NC score	0.072305 (rank : 870)	θ value	θ > 10 (rank : 1402)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1038	Shared Neighborhood Hits	203
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

ATX2L_HUMAN
NC score	0.072163 (rank : 871)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	1024	Target Neighborhood Hits	443	Shared Neighborhood Hits	147
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

IL3RB_MOUSE
NC score	0.072060 (rank : 872)	θ value	θ > 10 (rank : 1272)
Query Neighborhood Hits	1024	Target Neighborhood Hits	355	Shared Neighborhood Hits	160
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

ARHGF_HUMAN
NC score	0.071994 (rank : 873)	θ value	8.99809 (rank : 972)
Query Neighborhood Hits	1024	Target Neighborhood Hits	214	Shared Neighborhood Hits	78
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

MUC2_HUMAN
NC score	0.071890 (rank : 874)	θ value	θ > 10 (rank : 1353)
Query Neighborhood Hits	1024	Target Neighborhood Hits	906	Shared Neighborhood Hits	154
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MNT_MOUSE
NC score	0.071798 (rank : 875)	θ value	θ > 10 (rank : 1345)
Query Neighborhood Hits	1024	Target Neighborhood Hits	432	Shared Neighborhood Hits	115
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

C1QT8_HUMAN
NC score	0.071669 (rank : 876)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	1024	Target Neighborhood Hits	94	Shared Neighborhood Hits	47
SwissProt Accessions	P60827	Gene names	C1QTNF8
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 8 precursor.

SMRC2_MOUSE
NC score	0.071369 (rank : 877)	θ value	0.125558 (rank : 475)
Query Neighborhood Hits	1024	Target Neighborhood Hits	487	Shared Neighborhood Hits	119
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

ZAR1_MOUSE
NC score	0.071359 (rank : 878)	θ value	θ > 10 (rank : 1562)
Query Neighborhood Hits	1024	Target Neighborhood Hits	254	Shared Neighborhood Hits	96
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

P85B_MOUSE
NC score	0.071121 (rank : 879)	θ value	θ > 10 (rank : 1390)
Query Neighborhood Hits	1024	Target Neighborhood Hits	519	Shared Neighborhood Hits	99
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PRRT1_MOUSE
NC score	0.071116 (rank : 880)	θ value	0.0563607 (rank : 416)
Query Neighborhood Hits	1024	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

SASH1_HUMAN
NC score	0.071007 (rank : 881)	θ value	0.813845 (rank : 657)
Query Neighborhood Hits	1024	Target Neighborhood Hits	292	Shared Neighborhood Hits	125
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

XRCC1_HUMAN
NC score	0.070986 (rank : 882)	θ value	0.0252991 (rank : 355)
Query Neighborhood Hits	1024	Target Neighborhood Hits	131	Shared Neighborhood Hits	32
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ARMX2_MOUSE
NC score	0.070898 (rank : 883)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	166
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ZDHC8_MOUSE
NC score	0.070797 (rank : 884)	θ value	0.0961366 (rank : 458)
Query Neighborhood Hits	1024	Target Neighborhood Hits	243	Shared Neighborhood Hits	112
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

BMX_HUMAN
NC score	0.070697 (rank : 885)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	1024	Target Neighborhood Hits	942	Shared Neighborhood Hits	102
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

WASF3_HUMAN
NC score	0.070515 (rank : 886)	θ value	5.27518 (rank : 919)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

BMX_MOUSE
NC score	0.070388 (rank : 887)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	1024	Target Neighborhood Hits	912	Shared Neighborhood Hits	97
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BLNK_HUMAN
NC score	0.070294 (rank : 888)	θ value	2.36792 (rank : 764)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	67
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

NFRKB_MOUSE
NC score	0.070286 (rank : 889)	θ value	θ > 10 (rank : 1365)
Query Neighborhood Hits	1024	Target Neighborhood Hits	393	Shared Neighborhood Hits	135
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

XRCC1_MOUSE
NC score	0.070261 (rank : 890)	θ value	0.00390308 (rank : 232)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	38
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

TPO_MOUSE
NC score	0.070172 (rank : 891)	θ value	θ > 10 (rank : 1531)
Query Neighborhood Hits	1024	Target Neighborhood Hits	258	Shared Neighborhood Hits	119
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

BRD4_HUMAN
NC score	0.070120 (rank : 892)	θ value	5.27518 (rank : 883)
Query Neighborhood Hits	1024	Target Neighborhood Hits	851	Shared Neighborhood Hits	194
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

TRPV2_MOUSE
NC score	0.070113 (rank : 893)	θ value	θ > 10 (rank : 1536)
Query Neighborhood Hits	1024	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

FER_HUMAN
NC score	0.069956 (rank : 894)	θ value	θ > 10 (rank : 1229)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1278	Shared Neighborhood Hits	130
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

LR37A_HUMAN
NC score	0.069945 (rank : 895)	θ value	θ > 10 (rank : 1309)
Query Neighborhood Hits	1024	Target Neighborhood Hits	720	Shared Neighborhood Hits	150
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

SMOO_HUMAN
NC score	0.069908 (rank : 896)	θ value	3.0926 (rank : 835)
Query Neighborhood Hits	1024	Target Neighborhood Hits	391	Shared Neighborhood Hits	115
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TM108_MOUSE
NC score	0.069683 (rank : 897)	θ value	θ > 10 (rank : 1526)
Query Neighborhood Hits	1024	Target Neighborhood Hits	336	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ATX2L_MOUSE
NC score	0.069667 (rank : 898)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	1024	Target Neighborhood Hits	401	Shared Neighborhood Hits	142
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

PREX1_HUMAN
NC score	0.069611 (rank : 899)	θ value	θ > 10 (rank : 1410)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

SC24D_HUMAN
NC score	0.069570 (rank : 900)	θ value	0.0148317 (rank : 316)
Query Neighborhood Hits	1024	Target Neighborhood Hits	173	Shared Neighborhood Hits	73
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

ARHGG_MOUSE
NC score	0.069474 (rank : 901)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	1024	Target Neighborhood Hits	152	Shared Neighborhood Hits	63
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

PRCC_HUMAN
NC score	0.069410 (rank : 902)	θ value	1.06291 (rank : 697)
Query Neighborhood Hits	1024	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

ZDHC8_HUMAN
NC score	0.069385 (rank : 903)	θ value	0.0431538 (rank : 394)
Query Neighborhood Hits	1024	Target Neighborhood Hits	234	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

MUC5B_HUMAN
NC score	0.068997 (rank : 904)	θ value	θ > 10 (rank : 1354)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1020	Shared Neighborhood Hits	169
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PCQAP_MOUSE
NC score	0.068986 (rank : 905)	θ value	1.38821 (rank : 721)
Query Neighborhood Hits	1024	Target Neighborhood Hits	506	Shared Neighborhood Hits	111
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

MAVS_HUMAN
NC score	0.068933 (rank : 906)	θ value	θ > 10 (rank : 1325)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	106
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

SNX9_MOUSE
NC score	0.068872 (rank : 907)	θ value	θ > 10 (rank : 1493)
Query Neighborhood Hits	1024	Target Neighborhood Hits	141	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

MEF2B_MOUSE
NC score	0.068618 (rank : 908)	θ value	θ > 10 (rank : 1332)
Query Neighborhood Hits	1024	Target Neighborhood Hits	218	Shared Neighborhood Hits	127
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

IRS2_HUMAN
NC score	0.068557 (rank : 909)	θ value	2.36792 (rank : 776)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

GRIN1_MOUSE
NC score	0.068512 (rank : 910)	θ value	θ > 10 (rank : 1253)
Query Neighborhood Hits	1024	Target Neighborhood Hits	337	Shared Neighborhood Hits	103
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

CCNK_MOUSE
NC score	0.068422 (rank : 911)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	112
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

RRBP1_MOUSE
NC score	0.068343 (rank : 912)	θ value	θ > 10 (rank : 1443)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1650	Shared Neighborhood Hits	190
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NCOR2_MOUSE
NC score	0.068231 (rank : 913)	θ value	1.06291 (rank : 693)
Query Neighborhood Hits	1024	Target Neighborhood Hits	790	Shared Neighborhood Hits	169
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

LCP2_MOUSE
NC score	0.068180 (rank : 914)	θ value	θ > 10 (rank : 1306)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	65
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

BAG3_HUMAN
NC score	0.068084 (rank : 915)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	129
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

WNK2_HUMAN
NC score	0.068047 (rank : 916)	θ value	θ > 10 (rank : 1559)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1407	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

MBL2_MOUSE
NC score	0.068009 (rank : 917)	θ value	θ > 10 (rank : 1329)
Query Neighborhood Hits	1024	Target Neighborhood Hits	148	Shared Neighborhood Hits	46
SwissProt Accessions	P41317	Gene names	Mbl2
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (Mannan-binding protein) (RA-reactive factor P28A subunit) (RARF/P28A).

K1688_HUMAN
NC score	0.067860 (rank : 918)	θ value	θ > 10 (rank : 1294)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	78
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

P55G_HUMAN
NC score	0.067845 (rank : 919)	θ value	θ > 10 (rank : 1385)
Query Neighborhood Hits	1024	Target Neighborhood Hits	451	Shared Neighborhood Hits	75
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

TCRG1_MOUSE
NC score	0.067603 (rank : 920)	θ value	0.47712 (rank : 597)
Query Neighborhood Hits	1024	Target Neighborhood Hits	947	Shared Neighborhood Hits	139
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

AUTS2_HUMAN
NC score	0.067386 (rank : 921)	θ value	5.27518 (rank : 881)
Query Neighborhood Hits	1024	Target Neighborhood Hits	342	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

AATK_MOUSE
NC score	0.067352 (rank : 922)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	1024	Target Neighborhood Hits	942	Shared Neighborhood Hits	142
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

SF3B1_MOUSE
NC score	0.067340 (rank : 923)	θ value	θ > 10 (rank : 1458)
Query Neighborhood Hits	1024	Target Neighborhood Hits	352	Shared Neighborhood Hits	141
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

MBL1_MOUSE
NC score	0.067321 (rank : 924)	θ value	θ > 10 (rank : 1327)
Query Neighborhood Hits	1024	Target Neighborhood Hits	147	Shared Neighborhood Hits	48
SwissProt Accessions	P39039	Gene names	Mbl1
Domain Architecture
Description	Mannose-binding protein A precursor (MBP-A) (Mannan-binding protein) (Ra-reactive factor polysaccharide-binding component p28B polypeptide) (RaRF p28B).

CJ047_HUMAN
NC score	0.067287 (rank : 925)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	1024	Target Neighborhood Hits	164	Shared Neighborhood Hits	82
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

CTG1B_HUMAN
NC score	0.067198 (rank : 926)	θ value	θ > 10 (rank : 1157)
Query Neighborhood Hits	1024	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	P78358, Q7LBY4	Gene names	CTAG1B, CTAG, CTAG1, ESO1, LAGE2
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 1B (L antigen family member 2) (LAGE-2 protein) (Autoimmunogenic cancer/testis antigen NY-ESO-1).

EPN3_MOUSE
NC score	0.067082 (rank : 927)	θ value	θ > 10 (rank : 1210)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	134
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

GA2L1_MOUSE
NC score	0.067071 (rank : 928)	θ value	0.0148317 (rank : 308)
Query Neighborhood Hits	1024	Target Neighborhood Hits	114	Shared Neighborhood Hits	40
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GAK10_HUMAN
NC score	0.067057 (rank : 929)	θ value	3.0926 (rank : 816)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	132
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

TIAM1_MOUSE
NC score	0.066971 (rank : 930)	θ value	θ > 10 (rank : 1521)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PP1RA_HUMAN
NC score	0.066935 (rank : 931)	θ value	θ > 10 (rank : 1408)
Query Neighborhood Hits	1024	Target Neighborhood Hits	180	Shared Neighborhood Hits	68
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

EMIL2_HUMAN
NC score	0.066920 (rank : 932)	θ value	θ > 10 (rank : 1179)
Query Neighborhood Hits	1024	Target Neighborhood Hits	573	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

GRB14_MOUSE
NC score	0.066916 (rank : 933)	θ value	θ > 10 (rank : 1250)
Query Neighborhood Hits	1024	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

MAP4_HUMAN
NC score	0.066873 (rank : 934)	θ value	5.27518 (rank : 905)
Query Neighborhood Hits	1024	Target Neighborhood Hits	428	Shared Neighborhood Hits	113
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CEND3_HUMAN
NC score	0.066581 (rank : 935)	θ value	1.06291 (rank : 672)
Query Neighborhood Hits	1024	Target Neighborhood Hits	275	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

GRB14_HUMAN
NC score	0.066518 (rank : 936)	θ value	θ > 10 (rank : 1249)
Query Neighborhood Hits	1024	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

TIAM1_HUMAN
NC score	0.066448 (rank : 937)	θ value	θ > 10 (rank : 1520)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	36
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SASH1_MOUSE
NC score	0.066405 (rank : 938)	θ value	θ > 10 (rank : 1451)
Query Neighborhood Hits	1024	Target Neighborhood Hits	263	Shared Neighborhood Hits	100
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

MILK1_HUMAN
NC score	0.066369 (rank : 939)	θ value	0.0736092 (rank : 433)
Query Neighborhood Hits	1024	Target Neighborhood Hits	427	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TCOF_MOUSE
NC score	0.066254 (rank : 940)	θ value	θ > 10 (rank : 1518)
Query Neighborhood Hits	1024	Target Neighborhood Hits	471	Shared Neighborhood Hits	100
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

GTSE1_MOUSE
NC score	0.065982 (rank : 941)	θ value	θ > 10 (rank : 1255)
Query Neighborhood Hits	1024	Target Neighborhood Hits	245	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

SF3B1_HUMAN
NC score	0.065883 (rank : 942)	θ value	θ > 10 (rank : 1457)
Query Neighborhood Hits	1024	Target Neighborhood Hits	341	Shared Neighborhood Hits	134
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

NPBL_MOUSE
NC score	0.065869 (rank : 943)	θ value	8.99809 (rank : 1002)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1041	Shared Neighborhood Hits	167
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CD248_HUMAN
NC score	0.065839 (rank : 944)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	1024	Target Neighborhood Hits	679	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TF65_HUMAN
NC score	0.065819 (rank : 945)	θ value	0.163984 (rank : 493)
Query Neighborhood Hits	1024	Target Neighborhood Hits	115	Shared Neighborhood Hits	47
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

DOK2_MOUSE
NC score	0.065809 (rank : 946)	θ value	1.38821 (rank : 711)
Query Neighborhood Hits	1024	Target Neighborhood Hits	244	Shared Neighborhood Hits	123
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

RPTN_HUMAN
NC score	0.065748 (rank : 947)	θ value	θ > 10 (rank : 1441)
Query Neighborhood Hits	1024	Target Neighborhood Hits	406	Shared Neighborhood Hits	88
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

PAR10_HUMAN
NC score	0.065696 (rank : 948)	θ value	θ > 10 (rank : 1391)
Query Neighborhood Hits	1024	Target Neighborhood Hits	142	Shared Neighborhood Hits	67
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

ARHG3_HUMAN
NC score	0.065550 (rank : 949)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	1024	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

LRRK1_HUMAN
NC score	0.065183 (rank : 950)	θ value	θ > 10 (rank : 1310)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1237	Shared Neighborhood Hits	158
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

SMR3A_HUMAN
NC score	0.065082 (rank : 951)	θ value	θ > 10 (rank : 1490)
Query Neighborhood Hits	1024	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

EWS_HUMAN
NC score	0.064979 (rank : 952)	θ value	3.0926 (rank : 814)
Query Neighborhood Hits	1024	Target Neighborhood Hits	249	Shared Neighborhood Hits	76
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

CDN1C_HUMAN
NC score	0.064947 (rank : 953)	θ value	5.27518 (rank : 885)
Query Neighborhood Hits	1024	Target Neighborhood Hits	168	Shared Neighborhood Hits	63
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

ARHG3_MOUSE
NC score	0.064752 (rank : 954)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	1024	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ATX2_HUMAN
NC score	0.064728 (rank : 955)	θ value	4.03905 (rank : 849)
Query Neighborhood Hits	1024	Target Neighborhood Hits	375	Shared Neighborhood Hits	110
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

SHC2_HUMAN
NC score	0.064723 (rank : 956)	θ value	θ > 10 (rank : 1472)
Query Neighborhood Hits	1024	Target Neighborhood Hits	170	Shared Neighborhood Hits	66
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

ZAP70_MOUSE
NC score	0.064653 (rank : 957)	θ value	θ > 10 (rank : 1561)
Query Neighborhood Hits	1024	Target Neighborhood Hits	905	Shared Neighborhood Hits	97
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

LSD1_HUMAN
NC score	0.064502 (rank : 958)	θ value	θ > 10 (rank : 1312)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	162
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

FMN1A_MOUSE
NC score	0.064338 (rank : 959)	θ value	8.99809 (rank : 987)
Query Neighborhood Hits	1024	Target Neighborhood Hits	423	Shared Neighborhood Hits	135
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

TCRG1_HUMAN
NC score	0.064293 (rank : 960)	θ value	0.62314 (rank : 624)
Query Neighborhood Hits	1024	Target Neighborhood Hits	929	Shared Neighborhood Hits	130
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

K1688_MOUSE
NC score	0.064255 (rank : 961)	θ value	0.0330416 (rank : 369)
Query Neighborhood Hits	1024	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

ZAP70_HUMAN
NC score	0.064226 (rank : 962)	θ value	θ > 10 (rank : 1560)
Query Neighborhood Hits	1024	Target Neighborhood Hits	893	Shared Neighborhood Hits	97
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

FMN1B_MOUSE
NC score	0.064154 (rank : 963)	θ value	8.99809 (rank : 988)
Query Neighborhood Hits	1024	Target Neighborhood Hits	447	Shared Neighborhood Hits	129
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

ARHG8_MOUSE
NC score	0.064102 (rank : 964)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	1024	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

MYO15_MOUSE
NC score	0.064000 (rank : 965)	θ value	0.125558 (rank : 468)
Query Neighborhood Hits	1024	Target Neighborhood Hits	467	Shared Neighborhood Hits	180
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MAP4_MOUSE
NC score	0.063916 (rank : 966)	θ value	θ > 10 (rank : 1321)
Query Neighborhood Hits	1024	Target Neighborhood Hits	409	Shared Neighborhood Hits	99
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SHC1_HUMAN
NC score	0.063900 (rank : 967)	θ value	θ > 10 (rank : 1470)
Query Neighborhood Hits	1024	Target Neighborhood Hits	170	Shared Neighborhood Hits	64
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

ERBB2_HUMAN
NC score	0.063649 (rank : 968)	θ value	θ > 10 (rank : 1213)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1073	Shared Neighborhood Hits	160
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

TCOF_HUMAN
NC score	0.063603 (rank : 969)	θ value	θ > 10 (rank : 1517)
Query Neighborhood Hits	1024	Target Neighborhood Hits	543	Shared Neighborhood Hits	97
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ZN750_MOUSE
NC score	0.063481 (rank : 970)	θ value	θ > 10 (rank : 1567)
Query Neighborhood Hits	1024	Target Neighborhood Hits	346	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

JIP2_HUMAN
NC score	0.063405 (rank : 971)	θ value	θ > 10 (rank : 1289)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	141
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

SHD_HUMAN
NC score	0.063370 (rank : 972)	θ value	θ > 10 (rank : 1476)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

MADCA_HUMAN
NC score	0.063156 (rank : 973)	θ value	θ > 10 (rank : 1319)
Query Neighborhood Hits	1024	Target Neighborhood Hits	221	Shared Neighborhood Hits	70
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

TP53B_MOUSE
NC score	0.063082 (rank : 974)	θ value	θ > 10 (rank : 1530)
Query Neighborhood Hits	1024	Target Neighborhood Hits	644	Shared Neighborhood Hits	147
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MUCDL_MOUSE
NC score	0.063045 (rank : 975)	θ value	0.279714 (rank : 538)
Query Neighborhood Hits	1024	Target Neighborhood Hits	461	Shared Neighborhood Hits	117
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

LAD1_HUMAN
NC score	0.062994 (rank : 976)	θ value	θ > 10 (rank : 1302)
Query Neighborhood Hits	1024	Target Neighborhood Hits	441	Shared Neighborhood Hits	111
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

SPEG_MOUSE
NC score	0.062935 (rank : 977)	θ value	0.0563607 (rank : 420)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1959	Shared Neighborhood Hits	344
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SMRC2_HUMAN
NC score	0.062891 (rank : 978)	θ value	0.62314 (rank : 618)
Query Neighborhood Hits	1024	Target Neighborhood Hits	499	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

ATX7_HUMAN
NC score	0.062878 (rank : 979)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	1024	Target Neighborhood Hits	351	Shared Neighborhood Hits	129
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

WASF3_MOUSE
NC score	0.062867 (rank : 980)	θ value	θ > 10 (rank : 1557)
Query Neighborhood Hits	1024	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

NSD1_MOUSE
NC score	0.062861 (rank : 981)	θ value	0.279714 (rank : 540)
Query Neighborhood Hits	1024	Target Neighborhood Hits	472	Shared Neighborhood Hits	103
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

HCN2_HUMAN
NC score	0.062824 (rank : 982)	θ value	0.0148317 (rank : 309)
Query Neighborhood Hits	1024	Target Neighborhood Hits	369	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

BASP_HUMAN
NC score	0.062747 (rank : 983)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	1024	Target Neighborhood Hits	321	Shared Neighborhood Hits	64
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

KSYK_MOUSE
NC score	0.062728 (rank : 984)	θ value	θ > 10 (rank : 1301)
Query Neighborhood Hits	1024	Target Neighborhood Hits	944	Shared Neighborhood Hits	113
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

EPN1_HUMAN
NC score	0.062403 (rank : 985)	θ value	0.125558 (rank : 464)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

IRS2_MOUSE
NC score	0.062325 (rank : 986)	θ value	0.163984 (rank : 487)
Query Neighborhood Hits	1024	Target Neighborhood Hits	248	Shared Neighborhood Hits	79
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

FMN2_MOUSE
NC score	0.062298 (rank : 987)	θ value	θ > 10 (rank : 1239)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	117
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

DOCK1_HUMAN
NC score	0.062115 (rank : 988)	θ value	θ > 10 (rank : 1170)
Query Neighborhood Hits	1024	Target Neighborhood Hits	191	Shared Neighborhood Hits	107
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

ARHG1_HUMAN
NC score	0.061957 (rank : 989)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	1024	Target Neighborhood Hits	176	Shared Neighborhood Hits	73
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

SHE_MOUSE
NC score	0.061949 (rank : 990)	θ value	θ > 10 (rank : 1479)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

MAST4_HUMAN
NC score	0.061788 (rank : 991)	θ value	1.38821 (rank : 717)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1804	Shared Neighborhood Hits	354
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SYNPO_MOUSE
NC score	0.061775 (rank : 992)	θ value	θ > 10 (rank : 1510)
Query Neighborhood Hits	1024	Target Neighborhood Hits	242	Shared Neighborhood Hits	78
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

FOXN1_HUMAN
NC score	0.061758 (rank : 993)	θ value	θ > 10 (rank : 1240)
Query Neighborhood Hits	1024	Target Neighborhood Hits	377	Shared Neighborhood Hits	171
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

STS1_MOUSE
NC score	0.061704 (rank : 994)	θ value	θ > 10 (rank : 1506)
Query Neighborhood Hits	1024	Target Neighborhood Hits	104	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

GAK1_HUMAN
NC score	0.061638 (rank : 995)	θ value	1.06291 (rank : 681)
Query Neighborhood Hits	1024	Target Neighborhood Hits	268	Shared Neighborhood Hits	116
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

APS_HUMAN
NC score	0.061547 (rank : 996)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	1024	Target Neighborhood Hits	162	Shared Neighborhood Hits	61
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

SHC1_MOUSE
NC score	0.061536 (rank : 997)	θ value	θ > 10 (rank : 1471)
Query Neighborhood Hits	1024	Target Neighborhood Hits	180	Shared Neighborhood Hits	66
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SH21A_MOUSE
NC score	0.061472 (rank : 998)	θ value	θ > 10 (rank : 1463)
Query Neighborhood Hits	1024	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

PO121_HUMAN
NC score	0.061465 (rank : 999)	θ value	θ > 10 (rank : 1407)
Query Neighborhood Hits	1024	Target Neighborhood Hits	344	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

MLKL_HUMAN
NC score	0.061460 (rank : 1000)	θ value	θ > 10 (rank : 1338)
Query Neighborhood Hits	1024	Target Neighborhood Hits	600	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

ULK1_MOUSE
NC score	0.061374 (rank : 1001)	θ value	θ > 10 (rank : 1552)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1214	Shared Neighborhood Hits	270
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

SHC3_MOUSE
NC score	0.061253 (rank : 1002)	θ value	θ > 10 (rank : 1475)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHE_HUMAN
NC score	0.061215 (rank : 1003)	θ value	θ > 10 (rank : 1478)
Query Neighborhood Hits	1024	Target Neighborhood Hits	164	Shared Neighborhood Hits	55
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

STS1_HUMAN
NC score	0.061212 (rank : 1004)	θ value	θ > 10 (rank : 1505)
Query Neighborhood Hits	1024	Target Neighborhood Hits	106	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

CBX2_HUMAN
NC score	0.061202 (rank : 1005)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	118
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

KSYK_HUMAN
NC score	0.061180 (rank : 1006)	θ value	θ > 10 (rank : 1300)
Query Neighborhood Hits	1024	Target Neighborhood Hits	901	Shared Neighborhood Hits	95
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

PTN23_MOUSE
NC score	0.061094 (rank : 1007)	θ value	0.279714 (rank : 543)
Query Neighborhood Hits	1024	Target Neighborhood Hits	726	Shared Neighborhood Hits	195
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

ARHGG_HUMAN
NC score	0.060934 (rank : 1008)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	1024	Target Neighborhood Hits	129	Shared Neighborhood Hits	48
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

JIP3_HUMAN
NC score	0.060918 (rank : 1009)	θ value	8.99809 (rank : 993)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1039	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

BCL7C_MOUSE
NC score	0.060823 (rank : 1010)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	1024	Target Neighborhood Hits	170	Shared Neighborhood Hits	97
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

CTAG2_HUMAN
NC score	0.060790 (rank : 1011)	θ value	θ > 10 (rank : 1156)
Query Neighborhood Hits	1024	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	O75638, O75637, Q9BU80, Q9UJ89, Q9Y479	Gene names	CTAG2, ESO2, LAGE1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 2 (L antigen family member 1) (LAGE-1 protein) (ESO-2 protein).

BAZ2A_HUMAN
NC score	0.060779 (rank : 1012)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	1024	Target Neighborhood Hits	780	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

PDCD7_HUMAN
NC score	0.060753 (rank : 1013)	θ value	1.81305 (rank : 745)
Query Neighborhood Hits	1024	Target Neighborhood Hits	255	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

ARHG8_HUMAN
NC score	0.060545 (rank : 1014)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	1024	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

3BP2_HUMAN
NC score	0.060438 (rank : 1015)	θ value	5.27518 (rank : 875)
Query Neighborhood Hits	1024	Target Neighborhood Hits	296	Shared Neighborhood Hits	118
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

SLY_MOUSE
NC score	0.060299 (rank : 1016)	θ value	θ > 10 (rank : 1486)
Query Neighborhood Hits	1024	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

RBM12_MOUSE
NC score	0.060230 (rank : 1017)	θ value	θ > 10 (rank : 1420)
Query Neighborhood Hits	1024	Target Neighborhood Hits	313	Shared Neighborhood Hits	104
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

IL4RA_MOUSE
NC score	0.060182 (rank : 1018)	θ value	θ > 10 (rank : 1273)
Query Neighborhood Hits	1024	Target Neighborhood Hits	194	Shared Neighborhood Hits	75
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

CRTC1_MOUSE
NC score	0.060157 (rank : 1019)	θ value	θ > 10 (rank : 1148)
Query Neighborhood Hits	1024	Target Neighborhood Hits	230	Shared Neighborhood Hits	92
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

P55G_MOUSE
NC score	0.060122 (rank : 1020)	θ value	θ > 10 (rank : 1386)
Query Neighborhood Hits	1024	Target Neighborhood Hits	401	Shared Neighborhood Hits	66
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

FES_HUMAN
NC score	0.060001 (rank : 1021)	θ value	θ > 10 (rank : 1230)
Query Neighborhood Hits	1024	Target Neighborhood Hits	978	Shared Neighborhood Hits	94
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

K1683_HUMAN
NC score	0.059998 (rank : 1022)	θ value	θ > 10 (rank : 1293)
Query Neighborhood Hits	1024	Target Neighborhood Hits	240	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

TNK1_HUMAN
NC score	0.059976 (rank : 1023)	θ value	θ > 10 (rank : 1528)
Query Neighborhood Hits	1024	Target Neighborhood Hits	815	Shared Neighborhood Hits	93
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

MCF2_HUMAN
NC score	0.059919 (rank : 1024)	θ value	θ > 10 (rank : 1331)
Query Neighborhood Hits	1024	Target Neighborhood Hits	166	Shared Neighborhood Hits	31
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

JIP1_MOUSE
NC score	0.059889 (rank : 1025)	θ value	θ > 10 (rank : 1288)
Query Neighborhood Hits	1024	Target Neighborhood Hits	259	Shared Neighborhood Hits	119
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

HSH2D_HUMAN
NC score	0.059856 (rank : 1026)	θ value	θ > 10 (rank : 1265)
Query Neighborhood Hits	1024	Target Neighborhood Hits	159	Shared Neighborhood Hits	44
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

DIAP1_HUMAN
NC score	0.059720 (rank : 1027)	θ value	6.88961 (rank : 935)
Query Neighborhood Hits	1024	Target Neighborhood Hits	784	Shared Neighborhood Hits	137
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

RAI1_MOUSE
NC score	0.059719 (rank : 1028)	θ value	3.0926 (rank : 828)
Query Neighborhood Hits	1024	Target Neighborhood Hits	344	Shared Neighborhood Hits	106
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

WBS14_HUMAN
NC score	0.059610 (rank : 1029)	θ value	θ > 10 (rank : 1558)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

LTK_HUMAN
NC score	0.059565 (rank : 1030)	θ value	θ > 10 (rank : 1313)
Query Neighborhood Hits	1024	Target Neighborhood Hits	774	Shared Neighborhood Hits	78
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

EPHA1_HUMAN
NC score	0.059545 (rank : 1031)	θ value	θ > 10 (rank : 1184)
Query Neighborhood Hits	1024	Target Neighborhood Hits	997	Shared Neighborhood Hits	107
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EVL_HUMAN
NC score	0.059498 (rank : 1032)	θ value	θ > 10 (rank : 1221)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

RKHD1_HUMAN
NC score	0.059370 (rank : 1033)	θ value	0.00509761 (rank : 246)
Query Neighborhood Hits	1024	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

SHC2_MOUSE
NC score	0.059313 (rank : 1034)	θ value	θ > 10 (rank : 1473)
Query Neighborhood Hits	1024	Target Neighborhood Hits	144	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

ATX1_MOUSE
NC score	0.059309 (rank : 1035)	θ value	5.27518 (rank : 880)
Query Neighborhood Hits	1024	Target Neighborhood Hits	264	Shared Neighborhood Hits	98
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

ARHGA_MOUSE
NC score	0.059232 (rank : 1036)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	1024	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

SH21A_HUMAN
NC score	0.059215 (rank : 1037)	θ value	θ > 10 (rank : 1462)
Query Neighborhood Hits	1024	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

TULP4_HUMAN
NC score	0.059163 (rank : 1038)	θ value	θ > 10 (rank : 1542)
Query Neighborhood Hits	1024	Target Neighborhood Hits	426	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

EPHB6_HUMAN
NC score	0.059055 (rank : 1039)	θ value	θ > 10 (rank : 1208)
Query Neighborhood Hits	1024	Target Neighborhood Hits	912	Shared Neighborhood Hits	111
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

OBF1_HUMAN
NC score	0.059031 (rank : 1040)	θ value	θ > 10 (rank : 1383)
Query Neighborhood Hits	1024	Target Neighborhood Hits	203	Shared Neighborhood Hits	94
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

FES_MOUSE
NC score	0.058969 (rank : 1041)	θ value	θ > 10 (rank : 1231)
Query Neighborhood Hits	1024	Target Neighborhood Hits	980	Shared Neighborhood Hits	93
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

RYK_HUMAN
NC score	0.058951 (rank : 1042)	θ value	θ > 10 (rank : 1448)
Query Neighborhood Hits	1024	Target Neighborhood Hits	701	Shared Neighborhood Hits	66
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

ERBB2_MOUSE
NC score	0.058884 (rank : 1043)	θ value	0.365318 (rank : 556)
Query Neighborhood Hits	1024	Target Neighborhood Hits	918	Shared Neighborhood Hits	88
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

SF01_MOUSE
NC score	0.058788 (rank : 1044)	θ value	θ > 10 (rank : 1455)
Query Neighborhood Hits	1024	Target Neighborhood Hits	240	Shared Neighborhood Hits	93
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

IER5_MOUSE
NC score	0.058762 (rank : 1045)	θ value	0.279714 (rank : 535)
Query Neighborhood Hits	1024	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

GRB7_MOUSE
NC score	0.058750 (rank : 1046)	θ value	θ > 10 (rank : 1252)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	56
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

LTK_MOUSE
NC score	0.058725 (rank : 1047)	θ value	θ > 10 (rank : 1314)
Query Neighborhood Hits	1024	Target Neighborhood Hits	770	Shared Neighborhood Hits	81
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

EPHA1_MOUSE
NC score	0.058684 (rank : 1048)	θ value	θ > 10 (rank : 1185)
Query Neighborhood Hits	1024	Target Neighborhood Hits	958	Shared Neighborhood Hits	100
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

3BP1_MOUSE
NC score	0.058633 (rank : 1049)	θ value	3.0926 (rank : 796)
Query Neighborhood Hits	1024	Target Neighborhood Hits	238	Shared Neighborhood Hits	73
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

EPHB4_HUMAN
NC score	0.058590 (rank : 1050)	θ value	θ > 10 (rank : 1206)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1056	Shared Neighborhood Hits	110
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

ALK_MOUSE
NC score	0.058553 (rank : 1051)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	1024	Target Neighborhood Hits	811	Shared Neighborhood Hits	86
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

CK024_MOUSE
NC score	0.058542 (rank : 1052)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	1024	Target Neighborhood Hits	307	Shared Neighborhood Hits	92
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

SOX13_HUMAN
NC score	0.058517 (rank : 1053)	θ value	θ > 10 (rank : 1495)
Query Neighborhood Hits	1024	Target Neighborhood Hits	464	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ROS_HUMAN
NC score	0.058498 (rank : 1054)	θ value	θ > 10 (rank : 1440)
Query Neighborhood Hits	1024	Target Neighborhood Hits	907	Shared Neighborhood Hits	85
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

CITE4_HUMAN
NC score	0.058464 (rank : 1055)	θ value	2.36792 (rank : 766)
Query Neighborhood Hits	1024	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

EPHA5_MOUSE
NC score	0.058453 (rank : 1056)	θ value	θ > 10 (rank : 1193)
Query Neighborhood Hits	1024	Target Neighborhood Hits	950	Shared Neighborhood Hits	99
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

RYK_MOUSE
NC score	0.058299 (rank : 1057)	θ value	θ > 10 (rank : 1449)
Query Neighborhood Hits	1024	Target Neighborhood Hits	715	Shared Neighborhood Hits	67
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SPEG_HUMAN
NC score	0.058290 (rank : 1058)	θ value	0.00869519 (rank : 282)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1762	Shared Neighborhood Hits	300
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SHB_MOUSE
NC score	0.058262 (rank : 1059)	θ value	θ > 10 (rank : 1469)
Query Neighborhood Hits	1024	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

TIE1_HUMAN
NC score	0.058255 (rank : 1060)	θ value	θ > 10 (rank : 1522)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1241	Shared Neighborhood Hits	104
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CEND3_MOUSE
NC score	0.058094 (rank : 1061)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	1024	Target Neighborhood Hits	228	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

TNK1_MOUSE
NC score	0.058053 (rank : 1062)	θ value	θ > 10 (rank : 1529)
Query Neighborhood Hits	1024	Target Neighborhood Hits	806	Shared Neighborhood Hits	86
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TIE1_MOUSE
NC score	0.058042 (rank : 1063)	θ value	θ > 10 (rank : 1523)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1266	Shared Neighborhood Hits	105
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

EPN1_MOUSE
NC score	0.058029 (rank : 1064)	θ value	2.36792 (rank : 772)
Query Neighborhood Hits	1024	Target Neighborhood Hits	240	Shared Neighborhood Hits	102
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

EPHB6_MOUSE
NC score	0.058015 (rank : 1065)	θ value	θ > 10 (rank : 1209)
Query Neighborhood Hits	1024	Target Neighborhood Hits	906	Shared Neighborhood Hits	105
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FAK2_MOUSE
NC score	0.057929 (rank : 1066)	θ value	θ > 10 (rank : 1227)
Query Neighborhood Hits	1024	Target Neighborhood Hits	851	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

EPHB4_MOUSE
NC score	0.057905 (rank : 1067)	θ value	θ > 10 (rank : 1207)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1013	Shared Neighborhood Hits	106
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EWS_MOUSE
NC score	0.057810 (rank : 1068)	θ value	3.0926 (rank : 815)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	76
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

ERBB4_HUMAN
NC score	0.057713 (rank : 1069)	θ value	θ > 10 (rank : 1216)
Query Neighborhood Hits	1024	Target Neighborhood Hits	910	Shared Neighborhood Hits	90
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

EPHAA_HUMAN
NC score	0.057622 (rank : 1070)	θ value	θ > 10 (rank : 1200)
Query Neighborhood Hits	1024	Target Neighborhood Hits	960	Shared Neighborhood Hits	101
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

MY18B_HUMAN
NC score	0.057616 (rank : 1071)	θ value	θ > 10 (rank : 1357)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1299	Shared Neighborhood Hits	186
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

EPHA2_MOUSE
NC score	0.057547 (rank : 1072)	θ value	θ > 10 (rank : 1187)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1020	Shared Neighborhood Hits	97
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA6_HUMAN
NC score	0.057523 (rank : 1073)	θ value	θ > 10 (rank : 1194)
Query Neighborhood Hits	1024	Target Neighborhood Hits	959	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

AFF1_HUMAN
NC score	0.057520 (rank : 1074)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	1024	Target Neighborhood Hits	506	Shared Neighborhood Hits	111
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

EPHA2_HUMAN
NC score	0.057496 (rank : 1075)	θ value	θ > 10 (rank : 1186)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1021	Shared Neighborhood Hits	98
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

FAK2_HUMAN
NC score	0.057489 (rank : 1076)	θ value	θ > 10 (rank : 1226)
Query Neighborhood Hits	1024	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

DDR1_MOUSE
NC score	0.057458 (rank : 1077)	θ value	θ > 10 (rank : 1165)
Query Neighborhood Hits	1024	Target Neighborhood Hits	818	Shared Neighborhood Hits	82
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

JIP1_HUMAN
NC score	0.057410 (rank : 1078)	θ value	θ > 10 (rank : 1287)
Query Neighborhood Hits	1024	Target Neighborhood Hits	271	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

ENAM_MOUSE
NC score	0.057382 (rank : 1079)	θ value	θ > 10 (rank : 1182)
Query Neighborhood Hits	1024	Target Neighborhood Hits	229	Shared Neighborhood Hits	78
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

ALK_HUMAN
NC score	0.057370 (rank : 1080)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	1024	Target Neighborhood Hits	795	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

TIE2_HUMAN
NC score	0.057314 (rank : 1081)	θ value	θ > 10 (rank : 1524)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1192	Shared Neighborhood Hits	102
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

FCN1_MOUSE
NC score	0.057238 (rank : 1082)	θ value	θ > 10 (rank : 1228)
Query Neighborhood Hits	1024	Target Neighborhood Hits	173	Shared Neighborhood Hits	67
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

NUP53_HUMAN
NC score	0.057238 (rank : 1083)	θ value	θ > 10 (rank : 1382)
Query Neighborhood Hits	1024	Target Neighborhood Hits	156	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

GTSE1_HUMAN
NC score	0.057148 (rank : 1084)	θ value	θ > 10 (rank : 1254)
Query Neighborhood Hits	1024	Target Neighborhood Hits	193	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

EPHA6_MOUSE
NC score	0.057116 (rank : 1085)	θ value	θ > 10 (rank : 1195)
Query Neighborhood Hits	1024	Target Neighborhood Hits	946	Shared Neighborhood Hits	92
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

MLKL_MOUSE
NC score	0.057101 (rank : 1086)	θ value	θ > 10 (rank : 1339)
Query Neighborhood Hits	1024	Target Neighborhood Hits	707	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

SHB_HUMAN
NC score	0.057063 (rank : 1087)	θ value	θ > 10 (rank : 1468)
Query Neighborhood Hits	1024	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

TIE2_MOUSE
NC score	0.057028 (rank : 1088)	θ value	θ > 10 (rank : 1525)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1204	Shared Neighborhood Hits	101
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

EPHB3_HUMAN
NC score	0.057018 (rank : 1089)	θ value	θ > 10 (rank : 1204)
Query Neighborhood Hits	1024	Target Neighborhood Hits	996	Shared Neighborhood Hits	105
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHA8_MOUSE
NC score	0.056993 (rank : 1090)	θ value	θ > 10 (rank : 1199)
Query Neighborhood Hits	1024	Target Neighborhood Hits	969	Shared Neighborhood Hits	100
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

BCR_HUMAN
NC score	0.056973 (rank : 1091)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	1024	Target Neighborhood Hits	204	Shared Neighborhood Hits	51
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

PP1RA_MOUSE
NC score	0.056948 (rank : 1092)	θ value	θ > 10 (rank : 1409)
Query Neighborhood Hits	1024	Target Neighborhood Hits	175	Shared Neighborhood Hits	67
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

SHC3_HUMAN
NC score	0.056932 (rank : 1093)	θ value	θ > 10 (rank : 1474)
Query Neighborhood Hits	1024	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

EPHA5_HUMAN
NC score	0.056855 (rank : 1094)	θ value	θ > 10 (rank : 1192)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1009	Shared Neighborhood Hits	104
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

RSMB_HUMAN
NC score	0.056839 (rank : 1095)	θ value	1.06291 (rank : 700)
Query Neighborhood Hits	1024	Target Neighborhood Hits	117	Shared Neighborhood Hits	49
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

INP5E_HUMAN
NC score	0.056682 (rank : 1096)	θ value	θ > 10 (rank : 1274)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

TCAL5_HUMAN
NC score	0.056681 (rank : 1097)	θ value	θ > 10 (rank : 1516)
Query Neighborhood Hits	1024	Target Neighborhood Hits	806	Shared Neighborhood Hits	127
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

HGS_MOUSE
NC score	0.056680 (rank : 1098)	θ value	θ > 10 (rank : 1261)
Query Neighborhood Hits	1024	Target Neighborhood Hits	589	Shared Neighborhood Hits	139
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

EPHB3_MOUSE
NC score	0.056660 (rank : 1099)	θ value	θ > 10 (rank : 1205)
Query Neighborhood Hits	1024	Target Neighborhood Hits	996	Shared Neighborhood Hits	103
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

SRBP1_HUMAN
NC score	0.056592 (rank : 1100)	θ value	0.0736092 (rank : 439)
Query Neighborhood Hits	1024	Target Neighborhood Hits	225	Shared Neighborhood Hits	57
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

RON_MOUSE
NC score	0.056463 (rank : 1101)	θ value	θ > 10 (rank : 1435)
Query Neighborhood Hits	1024	Target Neighborhood Hits	836	Shared Neighborhood Hits	73
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

DDR1_HUMAN
NC score	0.056434 (rank : 1102)	θ value	θ > 10 (rank : 1164)
Query Neighborhood Hits	1024	Target Neighborhood Hits	819	Shared Neighborhood Hits	79
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

KI67_HUMAN
NC score	0.056287 (rank : 1103)	θ value	θ > 10 (rank : 1295)
Query Neighborhood Hits	1024	Target Neighborhood Hits	581	Shared Neighborhood Hits	107
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

SHD_MOUSE
NC score	0.056219 (rank : 1104)	θ value	θ > 10 (rank : 1477)
Query Neighborhood Hits	1024	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

GAB1_HUMAN
NC score	0.056212 (rank : 1105)	θ value	0.47712 (rank : 584)
Query Neighborhood Hits	1024	Target Neighborhood Hits	279	Shared Neighborhood Hits	102
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

EPHB1_HUMAN
NC score	0.056196 (rank : 1106)	θ value	θ > 10 (rank : 1201)
Query Neighborhood Hits	1024	Target Neighborhood Hits	988	Shared Neighborhood Hits	99
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

INSRR_MOUSE
NC score	0.056178 (rank : 1107)	θ value	θ > 10 (rank : 1276)
Query Neighborhood Hits	1024	Target Neighborhood Hits	961	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

EPHA8_HUMAN
NC score	0.056157 (rank : 1108)	θ value	θ > 10 (rank : 1198)
Query Neighborhood Hits	1024	Target Neighborhood Hits	956	Shared Neighborhood Hits	101
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

FGD3_HUMAN
NC score	0.056112 (rank : 1109)	θ value	θ > 10 (rank : 1232)
Query Neighborhood Hits	1024	Target Neighborhood Hits	249	Shared Neighborhood Hits	63
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

TTBK1_HUMAN
NC score	0.056097 (rank : 1110)	θ value	3.0926 (rank : 841)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1058	Shared Neighborhood Hits	165
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

EPHB2_HUMAN
NC score	0.056087 (rank : 1111)	θ value	θ > 10 (rank : 1202)
Query Neighborhood Hits	1024	Target Neighborhood Hits	983	Shared Neighborhood Hits	99
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

ARHGA_HUMAN
NC score	0.055982 (rank : 1112)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	1024	Target Neighborhood Hits	187	Shared Neighborhood Hits	36
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

RON_HUMAN
NC score	0.055977 (rank : 1113)	θ value	θ > 10 (rank : 1434)
Query Neighborhood Hits	1024	Target Neighborhood Hits	842	Shared Neighborhood Hits	79
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ALEX_MOUSE
NC score	0.055973 (rank : 1114)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	1024	Target Neighborhood Hits	197	Shared Neighborhood Hits	77
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

INSRR_HUMAN
NC score	0.055943 (rank : 1115)	θ value	θ > 10 (rank : 1275)
Query Neighborhood Hits	1024	Target Neighborhood Hits	950	Shared Neighborhood Hits	91
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

CEND1_HUMAN
NC score	0.055907 (rank : 1116)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	1024	Target Neighborhood Hits	284	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

EPHB2_MOUSE
NC score	0.055863 (rank : 1117)	θ value	θ > 10 (rank : 1203)
Query Neighborhood Hits	1024	Target Neighborhood Hits	982	Shared Neighborhood Hits	99
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

STAT2_MOUSE
NC score	0.055834 (rank : 1118)	θ value	0.00175202 (rank : 188)
Query Neighborhood Hits	1024	Target Neighborhood Hits	175	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

MOS_MOUSE
NC score	0.055762 (rank : 1119)	θ value	θ > 10 (rank : 1347)
Query Neighborhood Hits	1024	Target Neighborhood Hits	833	Shared Neighborhood Hits	79
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

UBP42_HUMAN
NC score	0.055757 (rank : 1120)	θ value	0.62314 (rank : 626)
Query Neighborhood Hits	1024	Target Neighborhood Hits	445	Shared Neighborhood Hits	145
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

MERTK_MOUSE
NC score	0.055709 (rank : 1121)	θ value	θ > 10 (rank : 1334)
Query Neighborhood Hits	1024	Target Neighborhood Hits	974	Shared Neighborhood Hits	86
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

IRAK1_HUMAN
NC score	0.055684 (rank : 1122)	θ value	θ > 10 (rank : 1279)
Query Neighborhood Hits	1024	Target Neighborhood Hits	820	Shared Neighborhood Hits	95
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

FAK1_HUMAN
NC score	0.055660 (rank : 1123)	θ value	θ > 10 (rank : 1224)
Query Neighborhood Hits	1024	Target Neighborhood Hits	850	Shared Neighborhood Hits	81
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

PTN23_HUMAN
NC score	0.055630 (rank : 1124)	θ value	0.00869519 (rank : 280)
Query Neighborhood Hits	1024	Target Neighborhood Hits	646	Shared Neighborhood Hits	159
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

IGF1R_MOUSE
NC score	0.055623 (rank : 1125)	θ value	θ > 10 (rank : 1268)
Query Neighborhood Hits	1024	Target Neighborhood Hits	973	Shared Neighborhood Hits	87
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

EPHA7_HUMAN
NC score	0.055608 (rank : 1126)	θ value	θ > 10 (rank : 1196)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1053	Shared Neighborhood Hits	104
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

CEND1_MOUSE
NC score	0.055606 (rank : 1127)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

ROR2_MOUSE
NC score	0.055572 (rank : 1128)	θ value	θ > 10 (rank : 1439)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1000	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

MOS_HUMAN
NC score	0.055528 (rank : 1129)	θ value	θ > 10 (rank : 1346)
Query Neighborhood Hits	1024	Target Neighborhood Hits	829	Shared Neighborhood Hits	77
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

STYK1_HUMAN
NC score	0.055464 (rank : 1130)	θ value	θ > 10 (rank : 1507)
Query Neighborhood Hits	1024	Target Neighborhood Hits	786	Shared Neighborhood Hits	71
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

APXL_HUMAN
NC score	0.055450 (rank : 1131)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	1024	Target Neighborhood Hits	553	Shared Neighborhood Hits	131
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

FAK1_MOUSE
NC score	0.055440 (rank : 1132)	θ value	θ > 10 (rank : 1225)
Query Neighborhood Hits	1024	Target Neighborhood Hits	850	Shared Neighborhood Hits	79
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

IRAK2_HUMAN
NC score	0.055377 (rank : 1133)	θ value	θ > 10 (rank : 1281)
Query Neighborhood Hits	1024	Target Neighborhood Hits	714	Shared Neighborhood Hits	76
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

SYNP2_HUMAN
NC score	0.055365 (rank : 1134)	θ value	θ > 10 (rank : 1509)
Query Neighborhood Hits	1024	Target Neighborhood Hits	323	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

LNK_HUMAN
NC score	0.055364 (rank : 1135)	θ value	θ > 10 (rank : 1308)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

EPHA7_MOUSE
NC score	0.055341 (rank : 1136)	θ value	θ > 10 (rank : 1197)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1025	Shared Neighborhood Hits	99
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

MERTK_HUMAN
NC score	0.055314 (rank : 1137)	θ value	θ > 10 (rank : 1333)
Query Neighborhood Hits	1024	Target Neighborhood Hits	988	Shared Neighborhood Hits	88
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

DIAP1_MOUSE
NC score	0.055290 (rank : 1138)	θ value	θ > 10 (rank : 1168)
Query Neighborhood Hits	1024	Target Neighborhood Hits	839	Shared Neighborhood Hits	141
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

EPHA4_MOUSE
NC score	0.055283 (rank : 1139)	θ value	θ > 10 (rank : 1191)
Query Neighborhood Hits	1024	Target Neighborhood Hits	982	Shared Neighborhood Hits	98
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

DMRTD_HUMAN
NC score	0.055258 (rank : 1140)	θ value	θ > 10 (rank : 1169)
Query Neighborhood Hits	1024	Target Neighborhood Hits	216	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

EPHA4_HUMAN
NC score	0.055228 (rank : 1141)	θ value	θ > 10 (rank : 1190)
Query Neighborhood Hits	1024	Target Neighborhood Hits	975	Shared Neighborhood Hits	98
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

RIPK3_MOUSE
NC score	0.055214 (rank : 1142)	θ value	θ > 10 (rank : 1433)
Query Neighborhood Hits	1024	Target Neighborhood Hits	867	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

IGF1R_HUMAN
NC score	0.055170 (rank : 1143)	θ value	θ > 10 (rank : 1267)
Query Neighborhood Hits	1024	Target Neighborhood Hits	977	Shared Neighborhood Hits	85
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

BI2L1_HUMAN
NC score	0.055119 (rank : 1144)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	1024	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

JPH2_MOUSE
NC score	0.055036 (rank : 1145)	θ value	0.813845 (rank : 646)
Query Neighborhood Hits	1024	Target Neighborhood Hits	279	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

ERBB3_HUMAN
NC score	0.055032 (rank : 1146)	θ value	θ > 10 (rank : 1214)
Query Neighborhood Hits	1024	Target Neighborhood Hits	918	Shared Neighborhood Hits	86
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

RIPK2_HUMAN
NC score	0.055014 (rank : 1147)	θ value	θ > 10 (rank : 1431)
Query Neighborhood Hits	1024	Target Neighborhood Hits	774	Shared Neighborhood Hits	72
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

EGFR_MOUSE
NC score	0.054944 (rank : 1148)	θ value	θ > 10 (rank : 1175)
Query Neighborhood Hits	1024	Target Neighborhood Hits	927	Shared Neighborhood Hits	87
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

CJ108_HUMAN
NC score	0.054922 (rank : 1149)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	1024	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

GUC2G_MOUSE
NC score	0.054922 (rank : 1150)	θ value	θ > 10 (rank : 1257)
Query Neighborhood Hits	1024	Target Neighborhood Hits	644	Shared Neighborhood Hits	69
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

EP400_HUMAN
NC score	0.054912 (rank : 1151)	θ value	0.00509761 (rank : 237)
Query Neighborhood Hits	1024	Target Neighborhood Hits	556	Shared Neighborhood Hits	141
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

KSR2_HUMAN
NC score	0.054895 (rank : 1152)	θ value	θ > 10 (rank : 1299)
Query Neighborhood Hits	1024	Target Neighborhood Hits	920	Shared Neighborhood Hits	122
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

HRBL_HUMAN
NC score	0.054869 (rank : 1153)	θ value	θ > 10 (rank : 1262)
Query Neighborhood Hits	1024	Target Neighborhood Hits	179	Shared Neighborhood Hits	86
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

MET_MOUSE
NC score	0.054845 (rank : 1154)	θ value	θ > 10 (rank : 1336)
Query Neighborhood Hits	1024	Target Neighborhood Hits	844	Shared Neighborhood Hits	79
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MN1_HUMAN
NC score	0.054827 (rank : 1155)	θ value	θ > 10 (rank : 1343)
Query Neighborhood Hits	1024	Target Neighborhood Hits	196	Shared Neighborhood Hits	72
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

INSR_HUMAN
NC score	0.054789 (rank : 1156)	θ value	θ > 10 (rank : 1277)
Query Neighborhood Hits	1024	Target Neighborhood Hits	963	Shared Neighborhood Hits	86
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

EGFR_HUMAN
NC score	0.054714 (rank : 1157)	θ value	θ > 10 (rank : 1174)
Query Neighborhood Hits	1024	Target Neighborhood Hits	939	Shared Neighborhood Hits	84
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

UFO_HUMAN
NC score	0.054617 (rank : 1158)	θ value	θ > 10 (rank : 1550)
Query Neighborhood Hits	1024	Target Neighborhood Hits	981	Shared Neighborhood Hits	93
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

MET_HUMAN
NC score	0.054587 (rank : 1159)	θ value	θ > 10 (rank : 1335)
Query Neighborhood Hits	1024	Target Neighborhood Hits	831	Shared Neighborhood Hits	77
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

CEND2_HUMAN
NC score	0.054528 (rank : 1160)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	1024	Target Neighborhood Hits	166	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

HGS_HUMAN
NC score	0.054485 (rank : 1161)	θ value	θ > 10 (rank : 1260)
Query Neighborhood Hits	1024	Target Neighborhood Hits	517	Shared Neighborhood Hits	101
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

RET_MOUSE
NC score	0.054466 (rank : 1162)	θ value	θ > 10 (rank : 1424)
Query Neighborhood Hits	1024	Target Neighborhood Hits	884	Shared Neighborhood Hits	77
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

DDR2_HUMAN
NC score	0.054461 (rank : 1163)	θ value	θ > 10 (rank : 1166)
Query Neighborhood Hits	1024	Target Neighborhood Hits	818	Shared Neighborhood Hits	78
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

STYK1_MOUSE
NC score	0.054407 (rank : 1164)	θ value	θ > 10 (rank : 1508)
Query Neighborhood Hits	1024	Target Neighborhood Hits	779	Shared Neighborhood Hits	73
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

M3K12_HUMAN
NC score	0.054386 (rank : 1165)	θ value	θ > 10 (rank : 1315)
Query Neighborhood Hits	1024	Target Neighborhood Hits	940	Shared Neighborhood Hits	114
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

PRR8_HUMAN
NC score	0.054385 (rank : 1166)	θ value	θ > 10 (rank : 1415)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

NTRK1_HUMAN
NC score	0.054361 (rank : 1167)	θ value	θ > 10 (rank : 1375)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1023	Shared Neighborhood Hits	81
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

ERBB3_MOUSE
NC score	0.054337 (rank : 1168)	θ value	θ > 10 (rank : 1215)
Query Neighborhood Hits	1024	Target Neighborhood Hits	898	Shared Neighborhood Hits	83
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

LIPS_HUMAN
NC score	0.054271 (rank : 1169)	θ value	0.813845 (rank : 649)
Query Neighborhood Hits	1024	Target Neighborhood Hits	314	Shared Neighborhood Hits	89
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

TRIO_HUMAN
NC score	0.054174 (rank : 1170)	θ value	0.00390308 (rank : 231)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1580	Shared Neighborhood Hits	173
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

UFO_MOUSE
NC score	0.054173 (rank : 1171)	θ value	θ > 10 (rank : 1551)
Query Neighborhood Hits	1024	Target Neighborhood Hits	988	Shared Neighborhood Hits	90
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

INSR_MOUSE
NC score	0.054171 (rank : 1172)	θ value	θ > 10 (rank : 1278)
Query Neighborhood Hits	1024	Target Neighborhood Hits	968	Shared Neighborhood Hits	84
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

NOLC1_HUMAN
NC score	0.054107 (rank : 1173)	θ value	θ > 10 (rank : 1368)
Query Neighborhood Hits	1024	Target Neighborhood Hits	452	Shared Neighborhood Hits	78
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

ROR2_HUMAN
NC score	0.054080 (rank : 1174)	θ value	θ > 10 (rank : 1438)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1014	Shared Neighborhood Hits	84
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

M3K12_MOUSE
NC score	0.054020 (rank : 1175)	θ value	θ > 10 (rank : 1316)
Query Neighborhood Hits	1024	Target Neighborhood Hits	957	Shared Neighborhood Hits	112
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

AAK1_HUMAN
NC score	0.054012 (rank : 1176)	θ value	0.279714 (rank : 519)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1077	Shared Neighborhood Hits	188
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

RET_HUMAN
NC score	0.054006 (rank : 1177)	θ value	θ > 10 (rank : 1423)
Query Neighborhood Hits	1024	Target Neighborhood Hits	873	Shared Neighborhood Hits	74
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

MLTK_HUMAN
NC score	0.053996 (rank : 1178)	θ value	θ > 10 (rank : 1341)
Query Neighborhood Hits	1024	Target Neighborhood Hits	911	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

TAF3_MOUSE
NC score	0.053977 (rank : 1179)	θ value	0.279714 (rank : 549)
Query Neighborhood Hits	1024	Target Neighborhood Hits	463	Shared Neighborhood Hits	61
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

RSMB_MOUSE
NC score	0.053958 (rank : 1180)	θ value	1.06291 (rank : 701)
Query Neighborhood Hits	1024	Target Neighborhood Hits	93	Shared Neighborhood Hits	41
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

ARAF_HUMAN
NC score	0.053953 (rank : 1181)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	1024	Target Neighborhood Hits	924	Shared Neighborhood Hits	102
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

IRAK3_MOUSE
NC score	0.053749 (rank : 1182)	θ value	θ > 10 (rank : 1283)
Query Neighborhood Hits	1024	Target Neighborhood Hits	628	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

SF3B4_HUMAN
NC score	0.053741 (rank : 1183)	θ value	0.279714 (rank : 547)
Query Neighborhood Hits	1024	Target Neighborhood Hits	445	Shared Neighborhood Hits	115
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

APC_HUMAN
NC score	0.053677 (rank : 1184)	θ value	0.62314 (rank : 605)
Query Neighborhood Hits	1024	Target Neighborhood Hits	603	Shared Neighborhood Hits	108
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

DDR2_MOUSE
NC score	0.053659 (rank : 1185)	θ value	θ > 10 (rank : 1167)
Query Neighborhood Hits	1024	Target Neighborhood Hits	813	Shared Neighborhood Hits	76
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

TYRO3_MOUSE
NC score	0.053534 (rank : 1186)	θ value	θ > 10 (rank : 1549)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1007	Shared Neighborhood Hits	84
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

ROR1_MOUSE
NC score	0.053523 (rank : 1187)	θ value	θ > 10 (rank : 1437)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1025	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR1_HUMAN
NC score	0.053521 (rank : 1188)	θ value	θ > 10 (rank : 1436)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1018	Shared Neighborhood Hits	82
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

RIN3_MOUSE
NC score	0.053490 (rank : 1189)	θ value	θ > 10 (rank : 1428)
Query Neighborhood Hits	1024	Target Neighborhood Hits	239	Shared Neighborhood Hits	87
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

HAPIP_HUMAN
NC score	0.053447 (rank : 1190)	θ value	θ > 10 (rank : 1258)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	36
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

FLT3_MOUSE
NC score	0.053412 (rank : 1191)	θ value	θ > 10 (rank : 1238)
Query Neighborhood Hits	1024	Target Neighborhood Hits	847	Shared Neighborhood Hits	76
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

TYRO3_HUMAN
NC score	0.053396 (rank : 1192)	θ value	θ > 10 (rank : 1548)
Query Neighborhood Hits	1024	Target Neighborhood Hits	995	Shared Neighborhood Hits	81
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

CI079_HUMAN
NC score	0.053339 (rank : 1193)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	1024	Target Neighborhood Hits	288	Shared Neighborhood Hits	94
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

RAF1_HUMAN
NC score	0.053285 (rank : 1194)	θ value	θ > 10 (rank : 1416)
Query Neighborhood Hits	1024	Target Neighborhood Hits	886	Shared Neighborhood Hits	88
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

EPHA3_HUMAN
NC score	0.053276 (rank : 1195)	θ value	θ > 10 (rank : 1188)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1005	Shared Neighborhood Hits	94
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

FLT3_HUMAN
NC score	0.053269 (rank : 1196)	θ value	θ > 10 (rank : 1237)
Query Neighborhood Hits	1024	Target Neighborhood Hits	843	Shared Neighborhood Hits	75
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

IRAK3_HUMAN
NC score	0.053269 (rank : 1197)	θ value	θ > 10 (rank : 1282)
Query Neighborhood Hits	1024	Target Neighborhood Hits	644	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

GRB10_MOUSE
NC score	0.053234 (rank : 1198)	θ value	θ > 10 (rank : 1248)
Query Neighborhood Hits	1024	Target Neighborhood Hits	156	Shared Neighborhood Hits	51
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

SLY_HUMAN
NC score	0.053218 (rank : 1199)	θ value	θ > 10 (rank : 1485)
Query Neighborhood Hits	1024	Target Neighborhood Hits	81	Shared Neighborhood Hits	52
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

EPHA3_MOUSE
NC score	0.053208 (rank : 1200)	θ value	θ > 10 (rank : 1189)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1009	Shared Neighborhood Hits	95
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

MLTK_MOUSE
NC score	0.053198 (rank : 1201)	θ value	θ > 10 (rank : 1342)
Query Neighborhood Hits	1024	Target Neighborhood Hits	874	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

BRAF1_HUMAN
NC score	0.053130 (rank : 1202)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	1024	Target Neighborhood Hits	883	Shared Neighborhood Hits	88
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

KIT_MOUSE
NC score	0.053087 (rank : 1203)	θ value	θ > 10 (rank : 1297)
Query Neighborhood Hits	1024	Target Neighborhood Hits	949	Shared Neighborhood Hits	78
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

ECM1_HUMAN
NC score	0.053072 (rank : 1204)	θ value	θ > 10 (rank : 1172)
Query Neighborhood Hits	1024	Target Neighborhood Hits	182	Shared Neighborhood Hits	76
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

PGFRA_HUMAN
NC score	0.053006 (rank : 1205)	θ value	θ > 10 (rank : 1398)
Query Neighborhood Hits	1024	Target Neighborhood Hits	980	Shared Neighborhood Hits	82
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
NC score	0.053002 (rank : 1206)	θ value	θ > 10 (rank : 1399)
Query Neighborhood Hits	1024	Target Neighborhood Hits	975	Shared Neighborhood Hits	80
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

ZYX_MOUSE
NC score	0.052985 (rank : 1207)	θ value	0.365318 (rank : 573)
Query Neighborhood Hits	1024	Target Neighborhood Hits	347	Shared Neighborhood Hits	88
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

SMAP1_MOUSE
NC score	0.052862 (rank : 1208)	θ value	θ > 10 (rank : 1488)
Query Neighborhood Hits	1024	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

KIT_HUMAN
NC score	0.052777 (rank : 1209)	θ value	θ > 10 (rank : 1296)
Query Neighborhood Hits	1024	Target Neighborhood Hits	953	Shared Neighborhood Hits	77
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

IF35_MOUSE
NC score	0.052775 (rank : 1210)	θ value	1.06291 (rank : 685)
Query Neighborhood Hits	1024	Target Neighborhood Hits	210	Shared Neighborhood Hits	66
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IRAK1_MOUSE
NC score	0.052773 (rank : 1211)	θ value	θ > 10 (rank : 1280)
Query Neighborhood Hits	1024	Target Neighborhood Hits	784	Shared Neighborhood Hits	80
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

RAF1_MOUSE
NC score	0.052727 (rank : 1212)	θ value	θ > 10 (rank : 1417)
Query Neighborhood Hits	1024	Target Neighborhood Hits	886	Shared Neighborhood Hits	89
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

EP400_MOUSE
NC score	0.052712 (rank : 1213)	θ value	θ > 10 (rank : 1183)
Query Neighborhood Hits	1024	Target Neighborhood Hits	592	Shared Neighborhood Hits	169
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

TRPV4_HUMAN
NC score	0.052697 (rank : 1214)	θ value	θ > 10 (rank : 1538)
Query Neighborhood Hits	1024	Target Neighborhood Hits	150	Shared Neighborhood Hits	83
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

PGFRB_MOUSE
NC score	0.052672 (rank : 1215)	θ value	θ > 10 (rank : 1401)
Query Neighborhood Hits	1024	Target Neighborhood Hits	960	Shared Neighborhood Hits	81
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

SPRR3_HUMAN
NC score	0.052626 (rank : 1216)	θ value	θ > 10 (rank : 1500)
Query Neighborhood Hits	1024	Target Neighborhood Hits	102	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

PDC6I_HUMAN
NC score	0.052574 (rank : 1217)	θ value	θ > 10 (rank : 1393)
Query Neighborhood Hits	1024	Target Neighborhood Hits	278	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

ZYX_HUMAN
NC score	0.052535 (rank : 1218)	θ value	0.163984 (rank : 497)
Query Neighborhood Hits	1024	Target Neighborhood Hits	387	Shared Neighborhood Hits	93
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

CU081_HUMAN
NC score	0.052474 (rank : 1219)	θ value	θ > 10 (rank : 1160)
Query Neighborhood Hits	1024	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

NFRKB_HUMAN
NC score	0.052446 (rank : 1220)	θ value	3.0926 (rank : 825)
Query Neighborhood Hits	1024	Target Neighborhood Hits	211	Shared Neighborhood Hits	60
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ARAF_MOUSE
NC score	0.052419 (rank : 1221)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	1024	Target Neighborhood Hits	874	Shared Neighborhood Hits	84
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

RECQ5_HUMAN
NC score	0.052374 (rank : 1222)	θ value	5.27518 (rank : 912)
Query Neighborhood Hits	1024	Target Neighborhood Hits	390	Shared Neighborhood Hits	128
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

PGFRB_HUMAN
NC score	0.052362 (rank : 1223)	θ value	θ > 10 (rank : 1400)
Query Neighborhood Hits	1024	Target Neighborhood Hits	962	Shared Neighborhood Hits	82
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

NTRK3_HUMAN
NC score	0.052306 (rank : 1224)	θ value	θ > 10 (rank : 1378)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1115	Shared Neighborhood Hits	85
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

RIPK2_MOUSE
NC score	0.052274 (rank : 1225)	θ value	θ > 10 (rank : 1432)
Query Neighborhood Hits	1024	Target Neighborhood Hits	776	Shared Neighborhood Hits	71
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK1_HUMAN
NC score	0.052225 (rank : 1226)	θ value	θ > 10 (rank : 1429)
Query Neighborhood Hits	1024	Target Neighborhood Hits	891	Shared Neighborhood Hits	87
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ENAM_HUMAN
NC score	0.052219 (rank : 1227)	θ value	θ > 10 (rank : 1181)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

TXLNA_HUMAN
NC score	0.052152 (rank : 1228)	θ value	θ > 10 (rank : 1545)
Query Neighborhood Hits	1024	Target Neighborhood Hits	982	Shared Neighborhood Hits	165
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

DAB1_HUMAN
NC score	0.052118 (rank : 1229)	θ value	θ > 10 (rank : 1161)
Query Neighborhood Hits	1024	Target Neighborhood Hits	219	Shared Neighborhood Hits	83
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

FGFR4_MOUSE
NC score	0.052065 (rank : 1230)	θ value	θ > 10 (rank : 1236)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1026	Shared Neighborhood Hits	83
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

MILK2_HUMAN
NC score	0.052048 (rank : 1231)	θ value	0.62314 (rank : 614)
Query Neighborhood Hits	1024	Target Neighborhood Hits	457	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

PER1_MOUSE
NC score	0.051962 (rank : 1232)	θ value	0.0148317 (rank : 314)
Query Neighborhood Hits	1024	Target Neighborhood Hits	235	Shared Neighborhood Hits	84
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

ULK1_HUMAN
NC score	0.051884 (rank : 1233)	θ value	0.365318 (rank : 571)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1121	Shared Neighborhood Hits	219
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

GRB7_HUMAN
NC score	0.051867 (rank : 1234)	θ value	θ > 10 (rank : 1251)
Query Neighborhood Hits	1024	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

LEUK_HUMAN
NC score	0.051813 (rank : 1235)	θ value	θ > 10 (rank : 1307)
Query Neighborhood Hits	1024	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

CSF1R_HUMAN
NC score	0.051790 (rank : 1236)	θ value	θ > 10 (rank : 1150)
Query Neighborhood Hits	1024	Target Neighborhood Hits	943	Shared Neighborhood Hits	76
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

PHLB1_MOUSE
NC score	0.051781 (rank : 1237)	θ value	0.125558 (rank : 471)
Query Neighborhood Hits	1024	Target Neighborhood Hits	678	Shared Neighborhood Hits	110
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RIPK1_MOUSE
NC score	0.051704 (rank : 1238)	θ value	θ > 10 (rank : 1430)
Query Neighborhood Hits	1024	Target Neighborhood Hits	874	Shared Neighborhood Hits	86
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ECT2_MOUSE
NC score	0.051701 (rank : 1239)	θ value	θ > 10 (rank : 1173)
Query Neighborhood Hits	1024	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

REL_MOUSE
NC score	0.051681 (rank : 1240)	θ value	θ > 10 (rank : 1422)
Query Neighborhood Hits	1024	Target Neighborhood Hits	77	Shared Neighborhood Hits	25
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

OBSCN_HUMAN
NC score	0.051619 (rank : 1241)	θ value	6.88961 (rank : 945)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1931	Shared Neighborhood Hits	315
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

RBM12_HUMAN
NC score	0.051534 (rank : 1242)	θ value	θ > 10 (rank : 1419)
Query Neighborhood Hits	1024	Target Neighborhood Hits	298	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SMAP1_HUMAN
NC score	0.051510 (rank : 1243)	θ value	θ > 10 (rank : 1487)
Query Neighborhood Hits	1024	Target Neighborhood Hits	98	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

NFAC1_HUMAN
NC score	0.051457 (rank : 1244)	θ value	θ > 10 (rank : 1363)
Query Neighborhood Hits	1024	Target Neighborhood Hits	312	Shared Neighborhood Hits	130
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SETBP_MOUSE
NC score	0.051365 (rank : 1245)	θ value	θ > 10 (rank : 1454)
Query Neighborhood Hits	1024	Target Neighborhood Hits	352	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

M3K13_HUMAN
NC score	0.051342 (rank : 1246)	θ value	θ > 10 (rank : 1317)
Query Neighborhood Hits	1024	Target Neighborhood Hits	911	Shared Neighborhood Hits	91
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

TMAP1_HUMAN
NC score	0.051337 (rank : 1247)	θ value	θ > 10 (rank : 1527)
Query Neighborhood Hits	1024	Target Neighborhood Hits	140	Shared Neighborhood Hits	51
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

RGNEF_MOUSE
NC score	0.051319 (rank : 1248)	θ value	θ > 10 (rank : 1425)
Query Neighborhood Hits	1024	Target Neighborhood Hits	641	Shared Neighborhood Hits	75
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

IQEC2_MOUSE
NC score	0.051245 (rank : 1249)	θ value	0.365318 (rank : 561)
Query Neighborhood Hits	1024	Target Neighborhood Hits	417	Shared Neighborhood Hits	110
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

ARHGB_HUMAN
NC score	0.051183 (rank : 1250)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	1024	Target Neighborhood Hits	375	Shared Neighborhood Hits	65
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

MUSK_HUMAN
NC score	0.051168 (rank : 1251)	θ value	θ > 10 (rank : 1355)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1074	Shared Neighborhood Hits	79
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

NTRK2_HUMAN
NC score	0.051108 (rank : 1252)	θ value	θ > 10 (rank : 1376)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1081	Shared Neighborhood Hits	84
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
NC score	0.051058 (rank : 1253)	θ value	θ > 10 (rank : 1377)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1088	Shared Neighborhood Hits	84
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

CSF1R_MOUSE
NC score	0.051038 (rank : 1254)	θ value	θ > 10 (rank : 1151)
Query Neighborhood Hits	1024	Target Neighborhood Hits	983	Shared Neighborhood Hits	77
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

TAB3_MOUSE
NC score	0.051007 (rank : 1255)	θ value	4.03905 (rank : 869)
Query Neighborhood Hits	1024	Target Neighborhood Hits	273	Shared Neighborhood Hits	93
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

FGFR4_HUMAN
NC score	0.050949 (rank : 1256)	θ value	θ > 10 (rank : 1235)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1037	Shared Neighborhood Hits	85
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

TNR6A_HUMAN
NC score	0.050940 (rank : 1257)	θ value	1.38821 (rank : 731)
Query Neighborhood Hits	1024	Target Neighborhood Hits	343	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

CENA1_HUMAN
NC score	0.050935 (rank : 1258)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	1024	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

MUSK_MOUSE
NC score	0.050924 (rank : 1259)	θ value	θ > 10 (rank : 1356)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1057	Shared Neighborhood Hits	79
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

ANPRB_MOUSE
NC score	0.050918 (rank : 1260)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	1024	Target Neighborhood Hits	607	Shared Neighborhood Hits	62
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

FYB_MOUSE
NC score	0.050865 (rank : 1261)	θ value	5.27518 (rank : 896)
Query Neighborhood Hits	1024	Target Neighborhood Hits	194	Shared Neighborhood Hits	60
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

NSD1_HUMAN
NC score	0.050837 (rank : 1262)	θ value	θ > 10 (rank : 1374)
Query Neighborhood Hits	1024	Target Neighborhood Hits	427	Shared Neighborhood Hits	86
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

ELOA3_HUMAN
NC score	0.050810 (rank : 1263)	θ value	0.0193708 (rank : 329)
Query Neighborhood Hits	1024	Target Neighborhood Hits	98	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

SOCS7_MOUSE
NC score	0.050736 (rank : 1264)	θ value	θ > 10 (rank : 1494)
Query Neighborhood Hits	1024	Target Neighborhood Hits	154	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

ETV5_MOUSE
NC score	0.050694 (rank : 1265)	θ value	θ > 10 (rank : 1220)
Query Neighborhood Hits	1024	Target Neighborhood Hits	328	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

GUC2F_HUMAN
NC score	0.050662 (rank : 1266)	θ value	θ > 10 (rank : 1256)
Query Neighborhood Hits	1024	Target Neighborhood Hits	740	Shared Neighborhood Hits	68
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

PER2_MOUSE
NC score	0.050658 (rank : 1267)	θ value	θ > 10 (rank : 1395)
Query Neighborhood Hits	1024	Target Neighborhood Hits	325	Shared Neighborhood Hits	117
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

MUC13_MOUSE
NC score	0.050584 (rank : 1268)	θ value	θ > 10 (rank : 1351)
Query Neighborhood Hits	1024	Target Neighborhood Hits	447	Shared Neighborhood Hits	79
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ANPRA_MOUSE
NC score	0.050546 (rank : 1269)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	1024	Target Neighborhood Hits	600	Shared Neighborhood Hits	60
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

RSMN_HUMAN
NC score	0.050488 (rank : 1270)	θ value	6.88961 (rank : 950)
Query Neighborhood Hits	1024	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
NC score	0.050488 (rank : 1271)	θ value	6.88961 (rank : 951)
Query Neighborhood Hits	1024	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

LARP4_MOUSE
NC score	0.050476 (rank : 1272)	θ value	θ > 10 (rank : 1304)
Query Neighborhood Hits	1024	Target Neighborhood Hits	260	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

FGD3_MOUSE
NC score	0.050474 (rank : 1273)	θ value	θ > 10 (rank : 1233)
Query Neighborhood Hits	1024	Target Neighborhood Hits	257	Shared Neighborhood Hits	45
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

RBM16_HUMAN
NC score	0.050404 (rank : 1274)	θ value	θ > 10 (rank : 1421)
Query Neighborhood Hits	1024	Target Neighborhood Hits	300	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

SMP1L_HUMAN
NC score	0.050372 (rank : 1275)	θ value	θ > 10 (rank : 1489)
Query Neighborhood Hits	1024	Target Neighborhood Hits	74	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

FOXN1_MOUSE
NC score	0.050302 (rank : 1276)	θ value	θ > 10 (rank : 1241)
Query Neighborhood Hits	1024	Target Neighborhood Hits	300	Shared Neighborhood Hits	127
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

CAC1G_HUMAN
NC score	0.050299 (rank : 1277)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	1024	Target Neighborhood Hits	587	Shared Neighborhood Hits	216
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SH24A_HUMAN
NC score	0.050245 (rank : 1278)	θ value	θ > 10 (rank : 1466)
Query Neighborhood Hits	1024	Target Neighborhood Hits	455	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

KSR1_HUMAN
NC score	0.050225 (rank : 1279)	θ value	θ > 10 (rank : 1298)
Query Neighborhood Hits	1024	Target Neighborhood Hits	867	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

CD248_MOUSE
NC score	0.050162 (rank : 1280)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	1024	Target Neighborhood Hits	578	Shared Neighborhood Hits	153
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GRB10_HUMAN
NC score	0.050136 (rank : 1281)	θ value	θ > 10 (rank : 1247)
Query Neighborhood Hits	1024	Target Neighborhood Hits	147	Shared Neighborhood Hits	52
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

FGD4_MOUSE
NC score	0.050131 (rank : 1282)	θ value	θ > 10 (rank : 1234)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

TACC3_HUMAN
NC score	0.050068 (rank : 1283)	θ value	θ > 10 (rank : 1511)
Query Neighborhood Hits	1024	Target Neighborhood Hits	779	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

M3K7_MOUSE
NC score	0.050065 (rank : 1284)	θ value	θ > 10 (rank : 1318)
Query Neighborhood Hits	1024	Target Neighborhood Hits	892	Shared Neighborhood Hits	78
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

CNTRB_MOUSE
NC score	0.050059 (rank : 1285)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1029	Shared Neighborhood Hits	142
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

TYK2_MOUSE
NC score	0.050056 (rank : 1286)	θ value	θ > 10 (rank : 1547)
Query Neighborhood Hits	1024	Target Neighborhood Hits	850	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

ANPRB_HUMAN
NC score	0.050006 (rank : 1287)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	1024	Target Neighborhood Hits	646	Shared Neighborhood Hits	64
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

S23IP_HUMAN
NC score	0.049685 (rank : 1288)	θ value	2.36792 (rank : 786)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

IQEC2_HUMAN
NC score	0.049611 (rank : 1289)	θ value	0.365318 (rank : 560)
Query Neighborhood Hits	1024	Target Neighborhood Hits	403	Shared Neighborhood Hits	106
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

LDB3_HUMAN
NC score	0.049446 (rank : 1290)	θ value	0.0563607 (rank : 413)
Query Neighborhood Hits	1024	Target Neighborhood Hits	497	Shared Neighborhood Hits	114
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

UB7I1_MOUSE
NC score	0.049109 (rank : 1291)	θ value	0.813845 (rank : 663)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

WBS14_MOUSE
NC score	0.049015 (rank : 1292)	θ value	1.81305 (rank : 760)
Query Neighborhood Hits	1024	Target Neighborhood Hits	171	Shared Neighborhood Hits	56
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

PDCD7_MOUSE
NC score	0.048888 (rank : 1293)	θ value	1.81305 (rank : 746)
Query Neighborhood Hits	1024	Target Neighborhood Hits	214	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

NFAC4_HUMAN
NC score	0.048769 (rank : 1294)	θ value	0.0193708 (rank : 332)
Query Neighborhood Hits	1024	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

LDB3_MOUSE
NC score	0.048496 (rank : 1295)	θ value	0.21417 (rank : 511)
Query Neighborhood Hits	1024	Target Neighborhood Hits	510	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

SEM6C_MOUSE
NC score	0.048431 (rank : 1296)	θ value	4.03905 (rank : 867)
Query Neighborhood Hits	1024	Target Neighborhood Hits	352	Shared Neighborhood Hits	171
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

FOXN4_HUMAN
NC score	0.048262 (rank : 1297)	θ value	0.0431538 (rank : 384)
Query Neighborhood Hits	1024	Target Neighborhood Hits	248	Shared Neighborhood Hits	93
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

RP3A_HUMAN
NC score	0.048155 (rank : 1298)	θ value	0.00020696 (rank : 102)
Query Neighborhood Hits	1024	Target Neighborhood Hits	305	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

CD2L7_HUMAN
NC score	0.047923 (rank : 1299)	θ value	0.0431538 (rank : 382)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1275	Shared Neighborhood Hits	188
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

IF4G1_HUMAN
NC score	0.047477 (rank : 1300)	θ value	1.81305 (rank : 741)
Query Neighborhood Hits	1024	Target Neighborhood Hits	347	Shared Neighborhood Hits	108
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

SOS1_HUMAN
NC score	0.046515 (rank : 1301)	θ value	1.81305 (rank : 755)
Query Neighborhood Hits	1024	Target Neighborhood Hits	274	Shared Neighborhood Hits	76
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

HCN2_MOUSE
NC score	0.046310 (rank : 1302)	θ value	0.279714 (rank : 534)
Query Neighborhood Hits	1024	Target Neighborhood Hits	278	Shared Neighborhood Hits	106
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

SREC2_HUMAN
NC score	0.046268 (rank : 1303)	θ value	0.0563607 (rank : 421)
Query Neighborhood Hits	1024	Target Neighborhood Hits	645	Shared Neighborhood Hits	90
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

RC3H1_HUMAN
NC score	0.045835 (rank : 1304)	θ value	8.99809 (rank : 1008)
Query Neighborhood Hits	1024	Target Neighborhood Hits	433	Shared Neighborhood Hits	114
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

SIN3A_HUMAN
NC score	0.045500 (rank : 1305)	θ value	0.125558 (rank : 474)
Query Neighborhood Hits	1024	Target Neighborhood Hits	180	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

WNK4_HUMAN
NC score	0.044661 (rank : 1306)	θ value	8.99809 (rank : 1023)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1043	Shared Neighborhood Hits	159
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

FARP2_HUMAN
NC score	0.044615 (rank : 1307)	θ value	0.47712 (rank : 583)
Query Neighborhood Hits	1024	Target Neighborhood Hits	240	Shared Neighborhood Hits	54
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

HCN4_HUMAN
NC score	0.044273 (rank : 1308)	θ value	0.0252991 (rank : 347)
Query Neighborhood Hits	1024	Target Neighborhood Hits	303	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

K0460_MOUSE
NC score	0.043898 (rank : 1309)	θ value	8.99809 (rank : 995)
Query Neighborhood Hits	1024	Target Neighborhood Hits	374	Shared Neighborhood Hits	92
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

IL4RA_HUMAN
NC score	0.043817 (rank : 1310)	θ value	0.62314 (rank : 611)
Query Neighborhood Hits	1024	Target Neighborhood Hits	144	Shared Neighborhood Hits	47
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

NCOR1_MOUSE
NC score	0.043462 (rank : 1311)	θ value	1.38821 (rank : 720)
Query Neighborhood Hits	1024	Target Neighborhood Hits	521	Shared Neighborhood Hits	91
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

TTBK2_HUMAN
NC score	0.043255 (rank : 1312)	θ value	0.47712 (rank : 598)
Query Neighborhood Hits	1024	Target Neighborhood Hits	822	Shared Neighborhood Hits	95
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

DEN1A_MOUSE
NC score	0.042965 (rank : 1313)	θ value	2.36792 (rank : 771)
Query Neighborhood Hits	1024	Target Neighborhood Hits	178	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

SYN2_HUMAN
NC score	0.042602 (rank : 1314)	θ value	8.99809 (rank : 1017)
Query Neighborhood Hits	1024	Target Neighborhood Hits	213	Shared Neighborhood Hits	73
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

AB1IP_MOUSE
NC score	0.042453 (rank : 1315)	θ value	0.279714 (rank : 520)
Query Neighborhood Hits	1024	Target Neighborhood Hits	181	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

DCC_MOUSE
NC score	0.042428 (rank : 1316)	θ value	2.36792 (rank : 770)
Query Neighborhood Hits	1024	Target Neighborhood Hits	896	Shared Neighborhood Hits	198
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

TTBK2_MOUSE
NC score	0.042391 (rank : 1317)	θ value	0.47712 (rank : 599)
Query Neighborhood Hits	1024	Target Neighborhood Hits	811	Shared Neighborhood Hits	89
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

B4GN4_HUMAN
NC score	0.042185 (rank : 1318)	θ value	0.0330416 (rank : 360)
Query Neighborhood Hits	1024	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

IL3RB_HUMAN
NC score	0.042065 (rank : 1319)	θ value	0.21417 (rank : 510)
Query Neighborhood Hits	1024	Target Neighborhood Hits	163	Shared Neighborhood Hits	51
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

MAGC1_HUMAN
NC score	0.041924 (rank : 1320)	θ value	3.0926 (rank : 821)
Query Neighborhood Hits	1024	Target Neighborhood Hits	431	Shared Neighborhood Hits	117
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SREC2_MOUSE
NC score	0.041914 (rank : 1321)	θ value	0.0252991 (rank : 353)
Query Neighborhood Hits	1024	Target Neighborhood Hits	605	Shared Neighborhood Hits	80
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

GP152_HUMAN
NC score	0.041863 (rank : 1322)	θ value	3.0926 (rank : 817)
Query Neighborhood Hits	1024	Target Neighborhood Hits	636	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

RIN3_HUMAN
NC score	0.041748 (rank : 1323)	θ value	3.0926 (rank : 831)
Query Neighborhood Hits	1024	Target Neighborhood Hits	227	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

FOXE2_HUMAN
NC score	0.041582 (rank : 1324)	θ value	2.36792 (rank : 774)
Query Neighborhood Hits	1024	Target Neighborhood Hits	236	Shared Neighborhood Hits	98
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

RANB9_HUMAN
NC score	0.041481 (rank : 1325)	θ value	3.0926 (rank : 829)
Query Neighborhood Hits	1024	Target Neighborhood Hits	179	Shared Neighborhood Hits	69
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

PER1_HUMAN
NC score	0.040754 (rank : 1326)	θ value	4.03905 (rank : 866)
Query Neighborhood Hits	1024	Target Neighborhood Hits	215	Shared Neighborhood Hits	70
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

ERRFI_MOUSE
NC score	0.040193 (rank : 1327)	θ value	0.279714 (rank : 530)
Query Neighborhood Hits	1024	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

K0460_HUMAN
NC score	0.039817 (rank : 1328)	θ value	8.99809 (rank : 994)
Query Neighborhood Hits	1024	Target Neighborhood Hits	357	Shared Neighborhood Hits	85
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

ULK2_HUMAN
NC score	0.039021 (rank : 1329)	θ value	3.0926 (rank : 842)
Query Neighborhood Hits	1024	Target Neighborhood Hits	979	Shared Neighborhood Hits	127
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

SIN3A_MOUSE
NC score	0.038527 (rank : 1330)	θ value	0.62314 (rank : 617)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	52
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

FOG1_MOUSE
NC score	0.038521 (rank : 1331)	θ value	6.88961 (rank : 938)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1237	Shared Neighborhood Hits	262
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

IRX3_HUMAN
NC score	0.038508 (rank : 1332)	θ value	0.0113563 (rank : 294)
Query Neighborhood Hits	1024	Target Neighborhood Hits	342	Shared Neighborhood Hits	44
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

ANXA7_MOUSE
NC score	0.038303 (rank : 1333)	θ value	0.365318 (rank : 552)
Query Neighborhood Hits	1024	Target Neighborhood Hits	142	Shared Neighborhood Hits	65
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

S3TC2_MOUSE
NC score	0.038217 (rank : 1334)	θ value	8.99809 (rank : 1011)
Query Neighborhood Hits	1024	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

MK15_HUMAN
NC score	0.038120 (rank : 1335)	θ value	1.38821 (rank : 718)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1038	Shared Neighborhood Hits	187
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

BAG4_HUMAN
NC score	0.037957 (rank : 1336)	θ value	0.279714 (rank : 522)
Query Neighborhood Hits	1024	Target Neighborhood Hits	96	Shared Neighborhood Hits	33
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

MINK1_MOUSE
NC score	0.037863 (rank : 1337)	θ value	0.279714 (rank : 537)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1451	Shared Neighborhood Hits	155
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

SMCA4_HUMAN
NC score	0.037858 (rank : 1338)	θ value	3.0926 (rank : 834)
Query Neighborhood Hits	1024	Target Neighborhood Hits	597	Shared Neighborhood Hits	145
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

IRS1_MOUSE
NC score	0.037541 (rank : 1339)	θ value	0.62314 (rank : 612)
Query Neighborhood Hits	1024	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

GOGA3_HUMAN
NC score	0.037464 (rank : 1340)	θ value	0.0961366 (rank : 448)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1317	Shared Neighborhood Hits	116
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

TSC1_HUMAN
NC score	0.037319 (rank : 1341)	θ value	1.38821 (rank : 733)
Query Neighborhood Hits	1024	Target Neighborhood Hits	765	Shared Neighborhood Hits	110
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ULK2_MOUSE
NC score	0.037249 (rank : 1342)	θ value	8.99809 (rank : 1020)
Query Neighborhood Hits	1024	Target Neighborhood Hits	943	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

AMOT_HUMAN
NC score	0.037131 (rank : 1343)	θ value	8.99809 (rank : 969)
Query Neighborhood Hits	1024	Target Neighborhood Hits	712	Shared Neighborhood Hits	117
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

PHLPP_HUMAN
NC score	0.036996 (rank : 1344)	θ value	0.0252991 (rank : 350)
Query Neighborhood Hits	1024	Target Neighborhood Hits	604	Shared Neighborhood Hits	138
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

GNAS1_HUMAN
NC score	0.036560 (rank : 1345)	θ value	0.0330416 (rank : 367)
Query Neighborhood Hits	1024	Target Neighborhood Hits	278	Shared Neighborhood Hits	91
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

R3HD1_HUMAN
NC score	0.036471 (rank : 1346)	θ value	8.99809 (rank : 1006)
Query Neighborhood Hits	1024	Target Neighborhood Hits	203	Shared Neighborhood Hits	65
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

PRP4B_HUMAN
NC score	0.036435 (rank : 1347)	θ value	3.0926 (rank : 827)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1030	Shared Neighborhood Hits	105
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

ANTR1_MOUSE
NC score	0.036359 (rank : 1348)	θ value	6.88961 (rank : 925)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

IRX5_HUMAN
NC score	0.036038 (rank : 1349)	θ value	0.813845 (rank : 645)
Query Neighborhood Hits	1024	Target Neighborhood Hits	362	Shared Neighborhood Hits	68
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

MK07_HUMAN
NC score	0.035974 (rank : 1350)	θ value	4.03905 (rank : 862)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1087	Shared Neighborhood Hits	160
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

CK056_MOUSE
NC score	0.035867 (rank : 1351)	θ value	0.813845 (rank : 635)
Query Neighborhood Hits	1024	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q3U2I3, Q3TWF5, Q6P543, Q80T93, Q811J6, Q8BI34, Q8VE55	Gene names	Kiaa1759
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf56 homolog.

GCNL2_HUMAN
NC score	0.035783 (rank : 1352)	θ value	0.21417 (rank : 506)
Query Neighborhood Hits	1024	Target Neighborhood Hits	159	Shared Neighborhood Hits	58
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

US6NL_HUMAN
NC score	0.035752 (rank : 1353)	θ value	2.36792 (rank : 791)
Query Neighborhood Hits	1024	Target Neighborhood Hits	201	Shared Neighborhood Hits	67
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

PB1_HUMAN
NC score	0.035611 (rank : 1354)	θ value	5.27518 (rank : 908)
Query Neighborhood Hits	1024	Target Neighborhood Hits	261	Shared Neighborhood Hits	62
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

RD23B_MOUSE
NC score	0.035364 (rank : 1355)	θ value	3.0926 (rank : 830)
Query Neighborhood Hits	1024	Target Neighborhood Hits	189	Shared Neighborhood Hits	49
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

FA8A1_HUMAN
NC score	0.035352 (rank : 1356)	θ value	4.03905 (rank : 859)
Query Neighborhood Hits	1024	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

ANTR1_HUMAN
NC score	0.035224 (rank : 1357)	θ value	8.99809 (rank : 970)
Query Neighborhood Hits	1024	Target Neighborhood Hits	128	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

TITIN_HUMAN
NC score	0.035214 (rank : 1358)	θ value	8.99809 (rank : 1018)
Query Neighborhood Hits	1024	Target Neighborhood Hits	2923	Shared Neighborhood Hits	291
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

BRSK1_HUMAN
NC score	0.034796 (rank : 1359)	θ value	1.38821 (rank : 706)
Query Neighborhood Hits	1024	Target Neighborhood Hits	942	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

DLG5_HUMAN
NC score	0.034757 (rank : 1360)	θ value	8.99809 (rank : 982)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1088	Shared Neighborhood Hits	166
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

ECM1_MOUSE
NC score	0.034705 (rank : 1361)	θ value	5.27518 (rank : 889)
Query Neighborhood Hits	1024	Target Neighborhood Hits	105	Shared Neighborhood Hits	48
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

LPP_MOUSE
NC score	0.034630 (rank : 1362)	θ value	5.27518 (rank : 903)
Query Neighborhood Hits	1024	Target Neighborhood Hits	247	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

BCAR3_HUMAN
NC score	0.034253 (rank : 1363)	θ value	8.99809 (rank : 977)
Query Neighborhood Hits	1024	Target Neighborhood Hits	129	Shared Neighborhood Hits	35
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

SCAP_HUMAN
NC score	0.033543 (rank : 1364)	θ value	0.0736092 (rank : 437)
Query Neighborhood Hits	1024	Target Neighborhood Hits	368	Shared Neighborhood Hits	74
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

PLXB1_HUMAN
NC score	0.033431 (rank : 1365)	θ value	0.21417 (rank : 515)
Query Neighborhood Hits	1024	Target Neighborhood Hits	360	Shared Neighborhood Hits	115
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

FOXN4_MOUSE
NC score	0.033210 (rank : 1366)	θ value	0.163984 (rank : 485)
Query Neighborhood Hits	1024	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

FOXC1_MOUSE
NC score	0.033209 (rank : 1367)	θ value	0.00390308 (rank : 226)
Query Neighborhood Hits	1024	Target Neighborhood Hits	218	Shared Neighborhood Hits	61
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

MIA2_MOUSE
NC score	0.032850 (rank : 1368)	θ value	6.88961 (rank : 942)
Query Neighborhood Hits	1024	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

ANX11_MOUSE
NC score	0.032817 (rank : 1369)	θ value	1.06291 (rank : 668)
Query Neighborhood Hits	1024	Target Neighborhood Hits	200	Shared Neighborhood Hits	78
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

SNIP_MOUSE
NC score	0.032211 (rank : 1370)	θ value	2.36792 (rank : 788)
Query Neighborhood Hits	1024	Target Neighborhood Hits	319	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

GGA3_MOUSE
NC score	0.032006 (rank : 1371)	θ value	5.27518 (rank : 897)
Query Neighborhood Hits	1024	Target Neighborhood Hits	148	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

RPGF1_HUMAN
NC score	0.031837 (rank : 1372)	θ value	5.27518 (rank : 915)
Query Neighborhood Hits	1024	Target Neighborhood Hits	262	Shared Neighborhood Hits	94
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

WEE1_HUMAN
NC score	0.031832 (rank : 1373)	θ value	5.27518 (rank : 920)
Query Neighborhood Hits	1024	Target Neighborhood Hits	777	Shared Neighborhood Hits	77
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

FOXK1_MOUSE
NC score	0.031357 (rank : 1374)	θ value	2.36792 (rank : 775)
Query Neighborhood Hits	1024	Target Neighborhood Hits	215	Shared Neighborhood Hits	65
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

SOX17_MOUSE
NC score	0.031333 (rank : 1375)	θ value	0.62314 (rank : 619)
Query Neighborhood Hits	1024	Target Neighborhood Hits	223	Shared Neighborhood Hits	84
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

M3K6_HUMAN
NC score	0.031040 (rank : 1376)	θ value	5.27518 (rank : 904)
Query Neighborhood Hits	1024	Target Neighborhood Hits	889	Shared Neighborhood Hits	91
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

MAST3_HUMAN
NC score	0.030607 (rank : 1377)	θ value	0.0431538 (rank : 387)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1128	Shared Neighborhood Hits	145
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MYLK_HUMAN
NC score	0.030604 (rank : 1378)	θ value	1.06291 (rank : 692)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1328	Shared Neighborhood Hits	108
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

DIAP2_HUMAN
NC score	0.030507 (rank : 1379)	θ value	8.99809 (rank : 981)
Query Neighborhood Hits	1024	Target Neighborhood Hits	342	Shared Neighborhood Hits	75
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

APC_MOUSE
NC score	0.030424 (rank : 1380)	θ value	8.99809 (rank : 971)
Query Neighborhood Hits	1024	Target Neighborhood Hits	441	Shared Neighborhood Hits	52
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

IER5_HUMAN
NC score	0.030399 (rank : 1381)	θ value	8.99809 (rank : 992)
Query Neighborhood Hits	1024	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VY09, Q8WY68, Q9NY49, Q9NZP9	Gene names	IER5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

PCX3_MOUSE
NC score	0.030230 (rank : 1382)	θ value	5.27518 (rank : 910)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

IRX1_HUMAN
NC score	0.030203 (rank : 1383)	θ value	1.06291 (rank : 686)
Query Neighborhood Hits	1024	Target Neighborhood Hits	285	Shared Neighborhood Hits	32
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

FUBP2_HUMAN
NC score	0.030122 (rank : 1384)	θ value	8.99809 (rank : 990)
Query Neighborhood Hits	1024	Target Neighborhood Hits	145	Shared Neighborhood Hits	59
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

RP1L1_MOUSE
NC score	0.030106 (rank : 1385)	θ value	8.99809 (rank : 1010)
Query Neighborhood Hits	1024	Target Neighborhood Hits	170	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

DBP_HUMAN
NC score	0.029549 (rank : 1386)	θ value	0.47712 (rank : 581)
Query Neighborhood Hits	1024	Target Neighborhood Hits	136	Shared Neighborhood Hits	37
SwissProt Accessions	Q10586	Gene names	DBP
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein) (TAXREB302).

M3K14_HUMAN
NC score	0.029468 (rank : 1387)	θ value	8.99809 (rank : 997)
Query Neighborhood Hits	1024	Target Neighborhood Hits	887	Shared Neighborhood Hits	104
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

RANB3_HUMAN
NC score	0.029394 (rank : 1388)	θ value	1.38821 (rank : 724)
Query Neighborhood Hits	1024	Target Neighborhood Hits	117	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

DYN1_HUMAN
NC score	0.029260 (rank : 1389)	θ value	0.279714 (rank : 526)
Query Neighborhood Hits	1024	Target Neighborhood Hits	216	Shared Neighborhood Hits	74
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DUS8_HUMAN
NC score	0.029219 (rank : 1390)	θ value	0.365318 (rank : 555)
Query Neighborhood Hits	1024	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DEN1A_HUMAN
NC score	0.028587 (rank : 1391)	θ value	8.99809 (rank : 980)
Query Neighborhood Hits	1024	Target Neighborhood Hits	176	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

E2AK4_HUMAN
NC score	0.028371 (rank : 1392)	θ value	5.27518 (rank : 888)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1012	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

ANX11_HUMAN
NC score	0.028265 (rank : 1393)	θ value	1.06291 (rank : 667)
Query Neighborhood Hits	1024	Target Neighborhood Hits	192	Shared Neighborhood Hits	75
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

DAAM2_HUMAN
NC score	0.028090 (rank : 1394)	θ value	1.38821 (rank : 710)
Query Neighborhood Hits	1024	Target Neighborhood Hits	350	Shared Neighborhood Hits	59
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

C2TA_HUMAN
NC score	0.028056 (rank : 1395)	θ value	6.88961 (rank : 930)
Query Neighborhood Hits	1024	Target Neighborhood Hits	190	Shared Neighborhood Hits	65
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

MPP4_HUMAN
NC score	0.027436 (rank : 1396)	θ value	3.0926 (rank : 823)
Query Neighborhood Hits	1024	Target Neighborhood Hits	205	Shared Neighborhood Hits	51
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

ADA12_MOUSE
NC score	0.027352 (rank : 1397)	θ value	5.27518 (rank : 878)
Query Neighborhood Hits	1024	Target Neighborhood Hits	474	Shared Neighborhood Hits	140
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

PEF1_MOUSE
NC score	0.027054 (rank : 1398)	θ value	0.125558 (rank : 470)
Query Neighborhood Hits	1024	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

ZDH18_HUMAN
NC score	0.026686 (rank : 1399)	θ value	8.99809 (rank : 1024)
Query Neighborhood Hits	1024	Target Neighborhood Hits	72	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NUE0, Q5JYH0, Q9H020	Gene names	ZDHHC18
Domain Architecture
Description	Palmitoyltransferase ZDHHC18 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 18) (DHHC-18).

CBL_HUMAN
NC score	0.026660 (rank : 1400)	θ value	5.27518 (rank : 884)
Query Neighborhood Hits	1024	Target Neighborhood Hits	353	Shared Neighborhood Hits	72
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CDKA2_MOUSE
NC score	0.026588 (rank : 1401)	θ value	0.47712 (rank : 576)
Query Neighborhood Hits	1024	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CPY4	Gene names	Cdk2ap2, D19Ertd144e, Doc1r
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase 2-associated protein 2 (CDK2-associated protein 2) (DOC-1-related protein) (DOC-1R).

ARMX2_HUMAN
NC score	0.026449 (rank : 1402)	θ value	4.03905 (rank : 848)
Query Neighborhood Hits	1024	Target Neighborhood Hits	134	Shared Neighborhood Hits	40
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

US6NL_MOUSE
NC score	0.026138 (rank : 1403)	θ value	1.06291 (rank : 704)
Query Neighborhood Hits	1024	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

DUS8_MOUSE
NC score	0.026101 (rank : 1404)	θ value	0.163984 (rank : 482)
Query Neighborhood Hits	1024	Target Neighborhood Hits	119	Shared Neighborhood Hits	29
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

NFM_HUMAN
NC score	0.026057 (rank : 1405)	θ value	1.06291 (rank : 694)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1328	Shared Neighborhood Hits	156
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SMCA2_HUMAN
NC score	0.025989 (rank : 1406)	θ value	1.38821 (rank : 728)
Query Neighborhood Hits	1024	Target Neighborhood Hits	503	Shared Neighborhood Hits	100
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

FOXC2_HUMAN
NC score	0.025959 (rank : 1407)	θ value	5.27518 (rank : 892)
Query Neighborhood Hits	1024	Target Neighborhood Hits	236	Shared Neighborhood Hits	63
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

LTB1L_HUMAN
NC score	0.025891 (rank : 1408)	θ value	1.81305 (rank : 743)
Query Neighborhood Hits	1024	Target Neighborhood Hits	553	Shared Neighborhood Hits	56
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MAST1_MOUSE
NC score	0.025326 (rank : 1409)	θ value	6.88961 (rank : 941)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1123	Shared Neighborhood Hits	137
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

CTGE4_HUMAN
NC score	0.024933 (rank : 1410)	θ value	0.0252991 (rank : 346)
Query Neighborhood Hits	1024	Target Neighborhood Hits	393	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

JADE2_HUMAN
NC score	0.024846 (rank : 1411)	θ value	0.47712 (rank : 586)
Query Neighborhood Hits	1024	Target Neighborhood Hits	199	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

LTB1S_HUMAN
NC score	0.024464 (rank : 1412)	θ value	1.81305 (rank : 744)
Query Neighborhood Hits	1024	Target Neighborhood Hits	502	Shared Neighborhood Hits	42
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PLS3_MOUSE
NC score	0.024404 (rank : 1413)	θ value	0.813845 (rank : 653)
Query Neighborhood Hits	1024	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JIZ9	Gene names	Plscr3
Domain Architecture
Description	Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3).

FOXC1_HUMAN
NC score	0.024237 (rank : 1414)	θ value	6.88961 (rank : 939)
Query Neighborhood Hits	1024	Target Neighborhood Hits	208	Shared Neighborhood Hits	63
SwissProt Accessions	Q12948, Q86UP7, Q9BYM1, Q9NUE5, Q9UDD0, Q9UP06	Gene names	FOXC1, FKHL7, FREAC3
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3).

TACC3_MOUSE
NC score	0.023924 (rank : 1415)	θ value	3.0926 (rank : 838)
Query Neighborhood Hits	1024	Target Neighborhood Hits	607	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

CD2L6_MOUSE
NC score	0.023534 (rank : 1416)	θ value	6.88961 (rank : 931)
Query Neighborhood Hits	1024	Target Neighborhood Hits	851	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

TIF1G_MOUSE
NC score	0.023190 (rank : 1417)	θ value	4.03905 (rank : 870)
Query Neighborhood Hits	1024	Target Neighborhood Hits	498	Shared Neighborhood Hits	84
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

MYCL1_HUMAN
NC score	0.022515 (rank : 1418)	θ value	4.03905 (rank : 863)
Query Neighborhood Hits	1024	Target Neighborhood Hits	146	Shared Neighborhood Hits	35
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MAGD1_HUMAN
NC score	0.022091 (rank : 1419)	θ value	1.06291 (rank : 690)
Query Neighborhood Hits	1024	Target Neighborhood Hits	130	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

FOXE3_HUMAN
NC score	0.022003 (rank : 1420)	θ value	0.0330416 (rank : 366)
Query Neighborhood Hits	1024	Target Neighborhood Hits	112	Shared Neighborhood Hits	28
SwissProt Accessions	Q13461, Q5SVY9, Q9NQV9	Gene names	FOXE3, FKHL12, FREAC8
Domain Architecture
Description	Forkhead box protein E3 (Forkhead-related protein FKHL12) (Forkhead- related transcription factor 8) (FREAC-8).

NMDE4_MOUSE
NC score	0.021948 (rank : 1421)	θ value	0.279714 (rank : 539)
Query Neighborhood Hits	1024	Target Neighborhood Hits	158	Shared Neighborhood Hits	49
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

KCNK4_HUMAN
NC score	0.021845 (rank : 1422)	θ value	0.0961366 (rank : 449)
Query Neighborhood Hits	1024	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

UBQL3_HUMAN
NC score	0.021679 (rank : 1423)	θ value	5.27518 (rank : 918)
Query Neighborhood Hits	1024	Target Neighborhood Hits	141	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

HNRPG_MOUSE
NC score	0.021587 (rank : 1424)	θ value	0.163984 (rank : 486)
Query Neighborhood Hits	1024	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	O35479	Gene names	Rbmx, Hnrnpg, Hnrpg, Rbmxp1, Rbmxrt
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein G (hnRNP G) (RNA-binding motif protein, X chromosome).

YETS2_HUMAN
NC score	0.020960 (rank : 1425)	θ value	6.88961 (rank : 964)
Query Neighborhood Hits	1024	Target Neighborhood Hits	212	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

DOC2B_MOUSE
NC score	0.020642 (rank : 1426)	θ value	8.99809 (rank : 984)
Query Neighborhood Hits	1024	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

NFAC2_HUMAN
NC score	0.020641 (rank : 1427)	θ value	4.03905 (rank : 865)
Query Neighborhood Hits	1024	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

ETV5_HUMAN
NC score	0.020577 (rank : 1428)	θ value	3.0926 (rank : 813)
Query Neighborhood Hits	1024	Target Neighborhood Hits	181	Shared Neighborhood Hits	61
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

PRDM2_HUMAN
NC score	0.020541 (rank : 1429)	θ value	0.47712 (rank : 591)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1135	Shared Neighborhood Hits	133
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PAPOA_MOUSE
NC score	0.020512 (rank : 1430)	θ value	0.813845 (rank : 651)
Query Neighborhood Hits	1024	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

UB7I1_HUMAN
NC score	0.020490 (rank : 1431)	θ value	8.99809 (rank : 1019)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

FA61A_MOUSE
NC score	0.020145 (rank : 1432)	θ value	6.88961 (rank : 937)
Query Neighborhood Hits	1024	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

ERF_MOUSE
NC score	0.020127 (rank : 1433)	θ value	1.06291 (rank : 676)
Query Neighborhood Hits	1024	Target Neighborhood Hits	160	Shared Neighborhood Hits	50
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

NRG2_HUMAN
NC score	0.019908 (rank : 1434)	θ value	6.88961 (rank : 944)
Query Neighborhood Hits	1024	Target Neighborhood Hits	419	Shared Neighborhood Hits	43
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

CUTL2_MOUSE
NC score	0.019881 (rank : 1435)	θ value	4.03905 (rank : 857)
Query Neighborhood Hits	1024	Target Neighborhood Hits	771	Shared Neighborhood Hits	87
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

RBM14_MOUSE
NC score	0.019713 (rank : 1436)	θ value	0.47712 (rank : 595)
Query Neighborhood Hits	1024	Target Neighborhood Hits	217	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

AAKG2_HUMAN
NC score	0.019483 (rank : 1437)	θ value	3.0926 (rank : 797)
Query Neighborhood Hits	1024	Target Neighborhood Hits	56	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UGJ0, Q53Y07, Q6NUI0, Q75MP4, Q9NUZ9, Q9UDN8, Q9ULX8	Gene names	PRKAG2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2) (H91620p).

TLE4_MOUSE
NC score	0.019137 (rank : 1438)	θ value	1.06291 (rank : 703)
Query Neighborhood Hits	1024	Target Neighborhood Hits	482	Shared Neighborhood Hits	113
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

AAKG2_MOUSE
NC score	0.019095 (rank : 1439)	θ value	3.0926 (rank : 798)
Query Neighborhood Hits	1024	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

HNRPG_HUMAN
NC score	0.019034 (rank : 1440)	θ value	0.62314 (rank : 610)
Query Neighborhood Hits	1024	Target Neighborhood Hits	245	Shared Neighborhood Hits	27
SwissProt Accessions	P38159, Q5JQ67, Q969R3	Gene names	RBMX, HNRPG, RBMXP1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein G (hnRNP G) (RNA-binding motif protein, X chromosome) (Glycoprotein p43).

5NT1B_HUMAN
NC score	0.018649 (rank : 1441)	θ value	6.88961 (rank : 922)
Query Neighborhood Hits	1024	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

NEUR4_HUMAN
NC score	0.018634 (rank : 1442)	θ value	0.47712 (rank : 588)
Query Neighborhood Hits	1024	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWR8, Q96D64	Gene names	NEU4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4).

TBX2_HUMAN
NC score	0.018634 (rank : 1443)	θ value	0.365318 (rank : 570)
Query Neighborhood Hits	1024	Target Neighborhood Hits	195	Shared Neighborhood Hits	59
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

4ET_MOUSE
NC score	0.018580 (rank : 1444)	θ value	8.99809 (rank : 966)
Query Neighborhood Hits	1024	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

CS021_HUMAN
NC score	0.018334 (rank : 1445)	θ value	8.99809 (rank : 979)
Query Neighborhood Hits	1024	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

NMDE4_HUMAN
NC score	0.018254 (rank : 1446)	θ value	0.21417 (rank : 514)
Query Neighborhood Hits	1024	Target Neighborhood Hits	133	Shared Neighborhood Hits	42
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

FOG1_HUMAN
NC score	0.018213 (rank : 1447)	θ value	0.62314 (rank : 608)
Query Neighborhood Hits	1024	Target Neighborhood Hits	981	Shared Neighborhood Hits	139
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

BRPF1_HUMAN
NC score	0.018096 (rank : 1448)	θ value	1.81305 (rank : 737)
Query Neighborhood Hits	1024	Target Neighborhood Hits	259	Shared Neighborhood Hits	41
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

RBM14_HUMAN
NC score	0.017930 (rank : 1449)	θ value	1.06291 (rank : 698)
Query Neighborhood Hits	1024	Target Neighborhood Hits	213	Shared Neighborhood Hits	20
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

ARI3A_HUMAN
NC score	0.017390 (rank : 1450)	θ value	8.99809 (rank : 973)
Query Neighborhood Hits	1024	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

DTX1_HUMAN
NC score	0.017321 (rank : 1451)	θ value	4.03905 (rank : 858)
Query Neighborhood Hits	1024	Target Neighborhood Hits	80	Shared Neighborhood Hits	30
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

FOXD2_MOUSE
NC score	0.017254 (rank : 1452)	θ value	5.27518 (rank : 894)
Query Neighborhood Hits	1024	Target Neighborhood Hits	130	Shared Neighborhood Hits	32
SwissProt Accessions	O35392	Gene names	Foxd2, Mf2
Domain Architecture
Description	Forkhead box protein D2 (Mesoderm/mesenchyme forkhead 2) (MF-2).

LOXL1_MOUSE
NC score	0.016918 (rank : 1453)	θ value	1.81305 (rank : 742)
Query Neighborhood Hits	1024	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

PUNC_MOUSE
NC score	0.016907 (rank : 1454)	θ value	0.279714 (rank : 544)
Query Neighborhood Hits	1024	Target Neighborhood Hits	501	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

FOXD2_HUMAN
NC score	0.016890 (rank : 1455)	θ value	6.88961 (rank : 940)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	38
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

ST5_HUMAN
NC score	0.016570 (rank : 1456)	θ value	3.0926 (rank : 837)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

STAT6_HUMAN
NC score	0.016506 (rank : 1457)	θ value	8.99809 (rank : 1016)
Query Neighborhood Hits	1024	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

TBC17_HUMAN
NC score	0.016450 (rank : 1458)	θ value	3.0926 (rank : 839)
Query Neighborhood Hits	1024	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HA65	Gene names	TBC1D17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

GP153_HUMAN
NC score	0.016430 (rank : 1459)	θ value	0.279714 (rank : 533)
Query Neighborhood Hits	1024	Target Neighborhood Hits	332	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

DVL2_MOUSE
NC score	0.016340 (rank : 1460)	θ value	5.27518 (rank : 887)
Query Neighborhood Hits	1024	Target Neighborhood Hits	233	Shared Neighborhood Hits	53
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

FOXJ3_HUMAN
NC score	0.016311 (rank : 1461)	θ value	8.99809 (rank : 989)
Query Neighborhood Hits	1024	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

FOXJ3_MOUSE
NC score	0.016127 (rank : 1462)	θ value	5.27518 (rank : 895)
Query Neighborhood Hits	1024	Target Neighborhood Hits	190	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

GATA4_HUMAN
NC score	0.016001 (rank : 1463)	θ value	0.47712 (rank : 585)
Query Neighborhood Hits	1024	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P43694	Gene names	GATA4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

PCD15_HUMAN
NC score	0.015861 (rank : 1464)	θ value	0.00035302 (rank : 122)
Query Neighborhood Hits	1024	Target Neighborhood Hits	289	Shared Neighborhood Hits	58
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

AXN2_MOUSE
NC score	0.015847 (rank : 1465)	θ value	2.36792 (rank : 763)
Query Neighborhood Hits	1024	Target Neighborhood Hits	116	Shared Neighborhood Hits	26
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

T240L_MOUSE
NC score	0.015699 (rank : 1466)	θ value	6.88961 (rank : 958)
Query Neighborhood Hits	1024	Target Neighborhood Hits	143	Shared Neighborhood Hits	37
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

TM16H_MOUSE
NC score	0.015654 (rank : 1467)	θ value	1.81305 (rank : 757)
Query Neighborhood Hits	1024	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PB70, Q69ZE4	Gene names	Tmem16h, Kiaa1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

ICB1_MOUSE
NC score	0.015515 (rank : 1468)	θ value	3.0926 (rank : 818)
Query Neighborhood Hits	1024	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

GATA4_MOUSE
NC score	0.015222 (rank : 1469)	θ value	1.06291 (rank : 684)
Query Neighborhood Hits	1024	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	Q08369, P97491, Q9QZK4	Gene names	Gata4, Gata-4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

NRDC_HUMAN
NC score	0.015045 (rank : 1470)	θ value	3.0926 (rank : 826)
Query Neighborhood Hits	1024	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	O43847, O15241, O15242, Q5VUL0, Q96HB2, Q9NU57	Gene names	NRD1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

TJAP1_MOUSE
NC score	0.014764 (rank : 1471)	θ value	6.88961 (rank : 960)
Query Neighborhood Hits	1024	Target Neighborhood Hits	295	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

CDC27_HUMAN
NC score	0.014733 (rank : 1472)	θ value	4.03905 (rank : 854)
Query Neighborhood Hits	1024	Target Neighborhood Hits	139	Shared Neighborhood Hits	13
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

SMRD3_HUMAN
NC score	0.014360 (rank : 1473)	θ value	1.38821 (rank : 729)
Query Neighborhood Hits	1024	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q6STE5, Q75MJ2, Q75MR8, Q92926, Q9BUH1	Gene names	SMARCD3, BAF60C
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C).

TR19L_HUMAN
NC score	0.014337 (rank : 1474)	θ value	1.81305 (rank : 758)
Query Neighborhood Hits	1024	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

NAB2_MOUSE
NC score	0.014254 (rank : 1475)	θ value	5.27518 (rank : 907)
Query Neighborhood Hits	1024	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q61127	Gene names	Nab2
Domain Architecture
Description	NGFI-A-binding protein 2 (EGR-1-binding protein 2).

MAGI2_MOUSE
NC score	0.014237 (rank : 1476)	θ value	8.99809 (rank : 998)
Query Neighborhood Hits	1024	Target Neighborhood Hits	370	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

PHX2B_HUMAN
NC score	0.014108 (rank : 1477)	θ value	1.81305 (rank : 748)
Query Neighborhood Hits	1024	Target Neighborhood Hits	407	Shared Neighborhood Hits	53
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
NC score	0.014108 (rank : 1478)	θ value	1.81305 (rank : 749)
Query Neighborhood Hits	1024	Target Neighborhood Hits	407	Shared Neighborhood Hits	53
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PCP2_MOUSE
NC score	0.014025 (rank : 1479)	θ value	5.27518 (rank : 909)
Query Neighborhood Hits	1024	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	P12660, P22941, Q3TV53	Gene names	Pcp2, Pcp-2
Domain Architecture
Description	Purkinje cell protein 2 (Protein PCD-5) (Purkinje cell-specific protein L7).

UBP8_HUMAN
NC score	0.013868 (rank : 1480)	θ value	1.81305 (rank : 759)
Query Neighborhood Hits	1024	Target Neighborhood Hits	751	Shared Neighborhood Hits	72
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

BHLH8_HUMAN
NC score	0.013759 (rank : 1481)	θ value	0.279714 (rank : 523)
Query Neighborhood Hits	1024	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

FOXD1_HUMAN
NC score	0.013682 (rank : 1482)	θ value	5.27518 (rank : 893)
Query Neighborhood Hits	1024	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q16676, Q12949	Gene names	FOXD1, FKHL8, FREAC4
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4).

HXA4_MOUSE
NC score	0.013622 (rank : 1483)	θ value	0.0113563 (rank : 293)
Query Neighborhood Hits	1024	Target Neighborhood Hits	379	Shared Neighborhood Hits	37
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).

DVL2_HUMAN
NC score	0.013284 (rank : 1484)	θ value	5.27518 (rank : 886)
Query Neighborhood Hits	1024	Target Neighborhood Hits	223	Shared Neighborhood Hits	35
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

SMRD3_MOUSE
NC score	0.013128 (rank : 1485)	θ value	3.0926 (rank : 836)
Query Neighborhood Hits	1024	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9Z1, Q921D3, Q9CX89, Q9DB99	Gene names	Smarcd3, Baf60c
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (mBAF60c).

CQ028_HUMAN
NC score	0.012993 (rank : 1486)	θ value	6.88961 (rank : 933)
Query Neighborhood Hits	1024	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

PI51C_HUMAN
NC score	0.012794 (rank : 1487)	θ value	1.06291 (rank : 696)
Query Neighborhood Hits	1024	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

HXD8_MOUSE
NC score	0.012545 (rank : 1488)	θ value	0.00298849 (rank : 212)
Query Neighborhood Hits	1024	Target Neighborhood Hits	333	Shared Neighborhood Hits	15
SwissProt Accessions	P23463	Gene names	Hoxd8, Hox-4.3, Hoxd-8
Domain Architecture
Description	Homeobox protein Hox-D8 (Hox-4.3) (Hox-5.4).

UBP51_HUMAN
NC score	0.012337 (rank : 1489)	θ value	1.38821 (rank : 734)
Query Neighborhood Hits	1024	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

YBOX2_MOUSE
NC score	0.012239 (rank : 1490)	θ value	3.0926 (rank : 844)
Query Neighborhood Hits	1024	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

MMP9_MOUSE
NC score	0.012164 (rank : 1491)	θ value	1.06291 (rank : 691)
Query Neighborhood Hits	1024	Target Neighborhood Hits	151	Shared Neighborhood Hits	36
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

CDX1_HUMAN
NC score	0.012158 (rank : 1492)	θ value	0.279714 (rank : 524)
Query Neighborhood Hits	1024	Target Neighborhood Hits	382	Shared Neighborhood Hits	38
SwissProt Accessions	P47902, Q4VAU4, Q9NYK8	Gene names	CDX1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

RAIN_HUMAN
NC score	0.012010 (rank : 1493)	θ value	1.38821 (rank : 723)
Query Neighborhood Hits	1024	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

MAGI2_HUMAN
NC score	0.011915 (rank : 1494)	θ value	3.0926 (rank : 822)
Query Neighborhood Hits	1024	Target Neighborhood Hits	373	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

BORG1_HUMAN
NC score	0.011779 (rank : 1495)	θ value	6.88961 (rank : 929)
Query Neighborhood Hits	1024	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

DMWD_MOUSE
NC score	0.011629 (rank : 1496)	θ value	8.99809 (rank : 983)
Query Neighborhood Hits	1024	Target Neighborhood Hits	282	Shared Neighborhood Hits	37
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

PLS3_HUMAN
NC score	0.011479 (rank : 1497)	θ value	8.99809 (rank : 1005)
Query Neighborhood Hits	1024	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRY6, Q8NBW6, Q96F13	Gene names	PLSCR3
Domain Architecture
Description	Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3).

ALG1_HUMAN
NC score	0.011102 (rank : 1498)	θ value	4.03905 (rank : 846)
Query Neighborhood Hits	1024	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BT22, Q6UVZ9, Q8N5Y4, Q9P2Y2	Gene names	ALG1, HMAT1, HMT1
Domain Architecture	No domain graphic available
Description	Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase) (GDP- Man:GlcNAc2-PP-dolichol mannosyltransferase) (Beta-1,4- mannosyltransferase) (Mannosyltransferase-1) (MT-1) (Hmat-1) (Asparagine-linked glycosylation protein 1 homolog).

SOX17_HUMAN
NC score	0.011018 (rank : 1499)	θ value	8.99809 (rank : 1014)
Query Neighborhood Hits	1024	Target Neighborhood Hits	108	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

HXD11_MOUSE
NC score	0.010867 (rank : 1500)	θ value	0.0431538 (rank : 385)
Query Neighborhood Hits	1024	Target Neighborhood Hits	376	Shared Neighborhood Hits	33
SwissProt Accessions	P23813	Gene names	Hoxd11, Hox-4.6, Hoxd-11
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4.6) (Hox-5.5).

HXA4_HUMAN
NC score	0.010687 (rank : 1501)	θ value	0.21417 (rank : 508)
Query Neighborhood Hits	1024	Target Neighborhood Hits	370	Shared Neighborhood Hits	44
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

PHLPP_MOUSE
NC score	0.010569 (rank : 1502)	θ value	0.47712 (rank : 589)
Query Neighborhood Hits	1024	Target Neighborhood Hits	394	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

RXRB_HUMAN
NC score	0.010567 (rank : 1503)	θ value	3.0926 (rank : 832)
Query Neighborhood Hits	1024	Target Neighborhood Hits	280	Shared Neighborhood Hits	69
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

KCNC3_HUMAN
NC score	0.010522 (rank : 1504)	θ value	0.813845 (rank : 647)
Query Neighborhood Hits	1024	Target Neighborhood Hits	256	Shared Neighborhood Hits	65
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

TOIP2_HUMAN
NC score	0.010161 (rank : 1505)	θ value	3.0926 (rank : 840)
Query Neighborhood Hits	1024	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

AMPD3_MOUSE
NC score	0.009938 (rank : 1506)	θ value	4.03905 (rank : 847)
Query Neighborhood Hits	1024	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	O08739, O88692	Gene names	Ampd3
Domain Architecture
Description	AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (AMP deaminase H-type) (Heart-type AMPD).

SALL3_HUMAN
NC score	0.009786 (rank : 1507)	θ value	0.21417 (rank : 517)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1066	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

UN119_HUMAN
NC score	0.009503 (rank : 1508)	θ value	8.99809 (rank : 1021)
Query Neighborhood Hits	1024	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q13432, O95126	Gene names	UNC119, RG4
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (HRG4).

PGBM_HUMAN
NC score	0.009339 (rank : 1509)	θ value	5.27518 (rank : 911)
Query Neighborhood Hits	1024	Target Neighborhood Hits	1113	Shared Neighborhood Hits	68
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

HXD1_MOUSE
NC score	0.008730 (rank : 1510)	θ value	1.38821 (rank : 715)
Query Neighborhood Hits	1024	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

PHF8_MOUSE
NC score	0.008639 (rank : 1511)	θ value	1.81305 (rank : 747)
Query Neighborhood Hits	1024	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

KBTB9_MOUSE
NC score	0.008485 (rank : 1512)	θ value	0.0736092 (rank : 432)
Query Neighborhood Hits	1024	Target Neighborhood Hits	197	Shared Neighborhood Hits	16
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

AXN2_HUMAN
NC score	0.008213 (rank : 1513)	θ value	5.27518 (rank : 882)
Query Neighborhood Hits	1024	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

RXRB_MOUSE
NC score	0.007957 (rank : 1514)	θ value	0.62314 (rank : 616)
Query Neighborhood Hits	1024	Target Neighborhood Hits	230	Shared Neighborhood Hits	53
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

ZN687_MOUSE
NC score	0.007842 (rank : 1515)	θ value	5.27518 (rank : 921)
Query Neighborhood Hits	1024	Target Neighborhood Hits	913	Shared Neighborhood Hits	117
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

DSCL1_HUMAN
NC score	0.007500 (rank : 1516)	θ value	3.0926 (rank : 812)
Query Neighborhood Hits	1024	Target Neighborhood Hits	589	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

SDK1_HUMAN
NC score	0.007290 (rank : 1517)	θ value	0.365318 (rank : 567)
Query Neighborhood Hits	1024	Target Neighborhood Hits	511	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

ZN438_HUMAN
NC score	0.007208 (rank : 1518)	θ value	6.88961 (rank : 965)
Query Neighborhood Hits	1024	Target Neighborhood Hits	906	Shared Neighborhood Hits	114
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ELK1_HUMAN
NC score	0.007182 (rank : 1519)	θ value	6.88961 (rank : 936)
Query Neighborhood Hits	1024	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

APOA5_HUMAN
NC score	0.007177 (rank : 1520)	θ value	5.27518 (rank : 879)
Query Neighborhood Hits	1024	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Q788, Q6UWK9, Q9UBJ3	Gene names	APOA5, RAP3
Domain Architecture	No domain graphic available
Description	Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) (Regeneration-associated protein 3).

TMC8_MOUSE
NC score	0.007118 (rank : 1521)	θ value	4.03905 (rank : 871)
Query Neighborhood Hits	1024	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TN58, Q3TAL0, Q3UWI0, Q7TQ67	Gene names	Tmc8, Ever2
Domain Architecture	No domain graphic available
Description	Transmembrane channel-like protein 8 (Epidermodysplasia verruciformis protein 2 homolog).

VEGFB_MOUSE
NC score	0.006965 (rank : 1522)	θ value	6.88961 (rank : 963)
Query Neighborhood Hits	1024	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	P49766, Q3UG04, Q5D0B1, Q64290	Gene names	Vegfb, Vrf
Domain Architecture
Description	Vascular endothelial growth factor B precursor (VEGF-B) (VEGF-related factor) (VRF).

LRCH4_MOUSE
NC score	0.006820 (rank : 1523)	θ value	3.0926 (rank : 820)
Query Neighborhood Hits	1024	Target Neighborhood Hits	302	Shared Neighborhood Hits	29
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

KBTB9_HUMAN
NC score	0.006493 (rank : 1524)	θ value	0.365318 (rank : 562)
Query Neighborhood Hits	1024	Target Neighborhood Hits	192	Shared Neighborhood Hits	11
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

SEM6C_HUMAN
NC score	0.006478 (rank : 1525)	θ value	1.81305 (rank : 753)
Query Neighborhood Hits	1024	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

NANO3_HUMAN
NC score	0.006472 (rank : 1526)	θ value	8.99809 (rank : 1000)
Query Neighborhood Hits	1024	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P60323	Gene names	NANOS3, NOS3
Domain Architecture	No domain graphic available
Description	Nanos homolog 3.

RREB1_HUMAN
NC score	0.006247 (rank : 1527)	θ value	0.21417 (rank : 516)
Query Neighborhood Hits	1024	Target Neighborhood Hits	879	Shared Neighborhood Hits	85
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

PDE3A_MOUSE
NC score	0.005998 (rank : 1528)	θ value	2.36792 (rank : 782)
Query Neighborhood Hits	1024	Target Neighborhood Hits	115	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

VTNC_MOUSE
NC score	0.005067 (rank : 1529)	θ value	3.0926 (rank : 843)
Query Neighborhood Hits	1024	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

KLF17_HUMAN
NC score	0.004718 (rank : 1530)	θ value	5.27518 (rank : 901)
Query Neighborhood Hits	1024	Target Neighborhood Hits	882	Shared Neighborhood Hits	135
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

EOMES_MOUSE
NC score	0.004611 (rank : 1531)	θ value	5.27518 (rank : 891)
Query Neighborhood Hits	1024	Target Neighborhood Hits	59	Shared Neighborhood Hits	10
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

RECQ4_MOUSE
NC score	0.004567 (rank : 1532)	θ value	8.99809 (rank : 1009)
Query Neighborhood Hits	1024	Target Neighborhood Hits	206	Shared Neighborhood Hits	33
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

TBX19_HUMAN
NC score	0.004369 (rank : 1533)	θ value	6.88961 (rank : 959)
Query Neighborhood Hits	1024	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TSC2_MOUSE
NC score	0.004294 (rank : 1534)	θ value	6.88961 (rank : 962)
Query Neighborhood Hits	1024	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

TRHDE_HUMAN
NC score	0.003912 (rank : 1535)	θ value	6.88961 (rank : 961)
Query Neighborhood Hits	1024	Target Neighborhood Hits	49	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKU6, Q6UWJ4	Gene names	TRHDE
Domain Architecture
Description	Thyrotropin-releasing hormone-degrading ectoenzyme (EC 3.4.19.6) (TRH- degrading ectoenzyme) (TRH-DE) (TRH-specific aminopeptidase) (Thyroliberinase) (Pyroglutamyl-peptidase II) (PAP-II).

SMAD6_MOUSE
NC score	0.003369 (rank : 1536)	θ value	6.88961 (rank : 954)
Query Neighborhood Hits	1024	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	O35182, Q9CW62	Gene names	Smad6, Madh6, Madh7, Msmad6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7).

DEMA_MOUSE
NC score	0.003082 (rank : 1537)	θ value	6.88961 (rank : 934)
Query Neighborhood Hits	1024	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

ACRO_HUMAN
NC score	0.002899 (rank : 1538)	θ value	0.47712 (rank : 574)
Query Neighborhood Hits	1024	Target Neighborhood Hits	291	Shared Neighborhood Hits	57
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

OST6_HUMAN
NC score	0.002541 (rank : 1539)	θ value	2.36792 (rank : 781)
Query Neighborhood Hits	1024	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

EVX1_HUMAN
NC score	0.002204 (rank : 1540)	θ value	1.38821 (rank : 713)
Query Neighborhood Hits	1024	Target Neighborhood Hits	349	Shared Neighborhood Hits	17
SwissProt Accessions	P49640	Gene names	EVX1
Domain Architecture
Description	Homeobox even-skipped homolog protein 1 (EVX-1).

TMPSD_MOUSE
NC score	0.002045 (rank : 1541)	θ value	4.03905 (rank : 872)
Query Neighborhood Hits	1024	Target Neighborhood Hits	334	Shared Neighborhood Hits	59
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

OLFL3_HUMAN
NC score	0.002006 (rank : 1542)	θ value	6.88961 (rank : 946)
Query Neighborhood Hits	1024	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRN5, Q53FR1, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2	Gene names	OLFML3
Domain Architecture
Description	Olfactomedin-like protein 3 precursor (HNOEL-iso) (hOLF44).

ABCA7_HUMAN
NC score	0.001957 (rank : 1543)	θ value	2.36792 (rank : 762)
Query Neighborhood Hits	1024	Target Neighborhood Hits	144	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

FOG2_MOUSE
NC score	0.001187 (rank : 1544)	θ value	0.813845 (rank : 643)
Query Neighborhood Hits	1024	Target Neighborhood Hits	714	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

ZN219_HUMAN
NC score	0.001047 (rank : 1545)	θ value	2.36792 (rank : 793)
Query Neighborhood Hits	1024	Target Neighborhood Hits	876	Shared Neighborhood Hits	111
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

SIGL5_HUMAN
NC score	-0.000425 (rank : 1546)	θ value	8.99809 (rank : 1012)
Query Neighborhood Hits	1024	Target Neighborhood Hits	246	Shared Neighborhood Hits	14
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

GLI1_HUMAN
NC score	-0.001447 (rank : 1547)	θ value	0.21417 (rank : 507)
Query Neighborhood Hits	1024	Target Neighborhood Hits	828	Shared Neighborhood Hits	78
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

ZBT45_HUMAN
NC score	-0.001724 (rank : 1548)	θ value	0.0252991 (rank : 356)
Query Neighborhood Hits	1024	Target Neighborhood Hits	901	Shared Neighborhood Hits	90
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

GLIS3_MOUSE
NC score	-0.001964 (rank : 1549)	θ value	1.81305 (rank : 740)
Query Neighborhood Hits	1024	Target Neighborhood Hits	861	Shared Neighborhood Hits	104
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

ZN592_HUMAN
NC score	-0.003971 (rank : 1550)	θ value	0.0431538 (rank : 395)
Query Neighborhood Hits	1024	Target Neighborhood Hits	762	Shared Neighborhood Hits	41
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

A2AP_MOUSE
NC score	-0.004420 (rank : 1551)	θ value	6.88961 (rank : 923)
Query Neighborhood Hits	1024	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q61247	Gene names	Serpinf2, Pli
Domain Architecture
Description	Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP).

KLF2_HUMAN
NC score	-0.004740 (rank : 1552)	θ value	0.813845 (rank : 648)
Query Neighborhood Hits	1024	Target Neighborhood Hits	755	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

PRELP_HUMAN
NC score	-0.005453 (rank : 1553)	θ value	6.88961 (rank : 947)
Query Neighborhood Hits	1024	Target Neighborhood Hits	295	Shared Neighborhood Hits	9
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

GLI1_MOUSE
NC score	-0.006280 (rank : 1554)	θ value	5.27518 (rank : 898)
Query Neighborhood Hits	1024	Target Neighborhood Hits	785	Shared Neighborhood Hits	63
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

KLF13_MOUSE
NC score	-0.006282 (rank : 1555)	θ value	0.47712 (rank : 587)
Query Neighborhood Hits	1024	Target Neighborhood Hits	757	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

SP7_MOUSE
NC score	-0.006405 (rank : 1556)	θ value	6.88961 (rank : 955)
Query Neighborhood Hits	1024	Target Neighborhood Hits	756	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

HIC1_MOUSE
NC score	-0.006426 (rank : 1557)	θ value	0.365318 (rank : 559)
Query Neighborhood Hits	1024	Target Neighborhood Hits	863	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

SLIK3_MOUSE
NC score	-0.006523 (rank : 1558)	θ value	6.88961 (rank : 953)
Query Neighborhood Hits	1024	Target Neighborhood Hits	308	Shared Neighborhood Hits	15
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

KLF13_HUMAN
NC score	-0.007121 (rank : 1559)	θ value	1.06291 (rank : 687)
Query Neighborhood Hits	1024	Target Neighborhood Hits	739	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

ZIC5_HUMAN
NC score	-0.007387 (rank : 1560)	θ value	1.81305 (rank : 761)
Query Neighborhood Hits	1024	Target Neighborhood Hits	774	Shared Neighborhood Hits	60
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

INSM1_HUMAN
NC score	-0.007430 (rank : 1561)	θ value	5.27518 (rank : 900)
Query Neighborhood Hits	1024	Target Neighborhood Hits	683	Shared Neighborhood Hits	43
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

SP7_HUMAN
NC score	-0.008733 (rank : 1562)	θ value	8.99809 (rank : 1015)
Query Neighborhood Hits	1024	Target Neighborhood Hits	734	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

GLIS3_HUMAN
NC score	-0.008995 (rank : 1563)	θ value	8.99809 (rank : 991)
Query Neighborhood Hits	1024	Target Neighborhood Hits	758	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

PRD10_HUMAN
NC score	-0.010268 (rank : 1564)	θ value	0.47712 (rank : 590)
Query Neighborhood Hits	1024	Target Neighborhood Hits	769	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NQV6, Q9ULI9	Gene names	PRDM10, KIAA1231, PFM7
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 10 (PR domain-containing protein 10).

ZN496_HUMAN
NC score	-0.011691 (rank : 1565)	θ value	2.36792 (rank : 795)
Query Neighborhood Hits	1024	Target Neighborhood Hits	743	Shared Neighborhood Hits	38
SwissProt Accessions	Q96IT1	Gene names	ZNF496
Domain Architecture	No domain graphic available
Description	Zinc finger protein 496.

ZN263_HUMAN
NC score	-0.012297 (rank : 1566)	θ value	2.36792 (rank : 794)
Query Neighborhood Hits	1024	Target Neighborhood Hits	795	Shared Neighborhood Hits	45
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).

ADA2A_MOUSE
NC score	-0.016847 (rank : 1567)	θ value	8.99809 (rank : 968)
Query Neighborhood Hits	1024	Target Neighborhood Hits	900	Shared Neighborhood Hits	30
SwissProt Accessions	Q01338	Gene names	Adra2a
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR).