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Network neighborhood for query Sequence : SCAP_HUMAN

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SCAP_HUMAN
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SCAP_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	368	Target Neighborhood Hits	368	Shared Neighborhood Hits	368
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

FBXW7_HUMAN
θ value	2.27762e-19 (rank : 2)	NC score	0.718518 (rank : 3)
Query Neighborhood Hits	368	Target Neighborhood Hits	433	Shared Neighborhood Hits	198
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
θ value	2.27762e-19 (rank : 3)	NC score	0.721195 (rank : 2)
Query Neighborhood Hits	368	Target Neighborhood Hits	365	Shared Neighborhood Hits	198
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

NPC1_MOUSE
θ value	6.85773e-16 (rank : 4)	NC score	0.339689 (rank : 235)
Query Neighborhood Hits	368	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	O35604, O35605	Gene names	Npc1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPC1_HUMAN
θ value	3.40345e-15 (rank : 5)	NC score	0.339414 (rank : 236)
Query Neighborhood Hits	368	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	O15118, Q9P130	Gene names	NPC1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

WDR5_HUMAN
θ value	1.02475e-11 (rank : 6)	NC score	0.669818 (rank : 9)
Query Neighborhood Hits	368	Target Neighborhood Hits	341	Shared Neighborhood Hits	205
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
θ value	1.02475e-11 (rank : 7)	NC score	0.669818 (rank : 10)
Query Neighborhood Hits	368	Target Neighborhood Hits	341	Shared Neighborhood Hits	205
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

FBW1A_HUMAN
θ value	1.47974e-10 (rank : 8)	NC score	0.703447 (rank : 4)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FBW1B_HUMAN
θ value	1.9326e-10 (rank : 9)	NC score	0.703157 (rank : 5)
Query Neighborhood Hits	368	Target Neighborhood Hits	327	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

WDR69_HUMAN
θ value	3.29651e-10 (rank : 10)	NC score	0.681809 (rank : 6)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	202
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

PK1IP_HUMAN
θ value	9.59137e-10 (rank : 11)	NC score	0.664211 (rank : 12)
Query Neighborhood Hits	368	Target Neighborhood Hits	277	Shared Neighborhood Hits	192
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

PK1IP_MOUSE
θ value	3.64472e-09 (rank : 12)	NC score	0.664599 (rank : 11)
Query Neighborhood Hits	368	Target Neighborhood Hits	313	Shared Neighborhood Hits	198
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

PTC2_MOUSE
θ value	1.06045e-08 (rank : 13)	NC score	0.272653 (rank : 271)
Query Neighborhood Hits	368	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O35595, Q546T0	Gene names	Ptch2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

PTC2_HUMAN
θ value	1.17247e-07 (rank : 14)	NC score	0.268500 (rank : 272)
Query Neighborhood Hits	368	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

PWP2_HUMAN
θ value	1.53129e-07 (rank : 15)	NC score	0.640224 (rank : 34)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	197
SwissProt Accessions	Q15269, Q96A77	Gene names	PWP2H, PWP2
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

APAF_HUMAN
θ value	1.99992e-07 (rank : 16)	NC score	0.647120 (rank : 26)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	202
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

NPCL1_HUMAN
θ value	1.99992e-07 (rank : 17)	NC score	0.291826 (rank : 261)
Query Neighborhood Hits	368	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHC9, Q6R3Q4, Q9UHC8	Gene names	NPC1L1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

NPCL1_MOUSE
θ value	2.61198e-07 (rank : 18)	NC score	0.292011 (rank : 260)
Query Neighborhood Hits	368	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q6T3U4, Q5SVX1	Gene names	Npc1l1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

TAF5L_HUMAN
θ value	2.61198e-07 (rank : 19)	NC score	0.644922 (rank : 29)
Query Neighborhood Hits	368	Target Neighborhood Hits	330	Shared Neighborhood Hits	202
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

WDR3_HUMAN
θ value	2.61198e-07 (rank : 20)	NC score	0.662734 (rank : 16)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

PLRG1_HUMAN
θ value	3.41135e-07 (rank : 21)	NC score	0.673015 (rank : 7)
Query Neighborhood Hits	368	Target Neighborhood Hits	318	Shared Neighborhood Hits	203
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

TEP1_HUMAN
θ value	3.41135e-07 (rank : 22)	NC score	0.608957 (rank : 86)
Query Neighborhood Hits	368	Target Neighborhood Hits	371	Shared Neighborhood Hits	203
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

PWP2_MOUSE
θ value	4.45536e-07 (rank : 23)	NC score	0.635721 (rank : 48)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	195
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

HMDH_HUMAN
θ value	7.59969e-07 (rank : 24)	NC score	0.195804 (rank : 296)
Query Neighborhood Hits	368	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	P04035, Q8N190	Gene names	HMGCR
Domain Architecture
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

KTNB1_HUMAN
θ value	7.59969e-07 (rank : 25)	NC score	0.645586 (rank : 27)
Query Neighborhood Hits	368	Target Neighborhood Hits	349	Shared Neighborhood Hits	205
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
θ value	7.59969e-07 (rank : 26)	NC score	0.645490 (rank : 28)
Query Neighborhood Hits	368	Target Neighborhood Hits	356	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

TAF5L_MOUSE
θ value	7.59969e-07 (rank : 27)	NC score	0.644266 (rank : 32)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	203
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

HMDH_MOUSE
θ value	9.92553e-07 (rank : 28)	NC score	0.194620 (rank : 297)
Query Neighborhood Hits	368	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q01237, Q5U4I2	Gene names	Hmgcr
Domain Architecture	No domain graphic available
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

PLRG1_MOUSE
θ value	9.92553e-07 (rank : 29)	NC score	0.671801 (rank : 8)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	202
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

WDR12_HUMAN
θ value	1.29631e-06 (rank : 30)	NC score	0.638412 (rank : 38)
Query Neighborhood Hits	368	Target Neighborhood Hits	300	Shared Neighborhood Hits	192
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

PTC1_HUMAN
θ value	1.69304e-06 (rank : 31)	NC score	0.261434 (rank : 278)
Query Neighborhood Hits	368	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

PTC1_MOUSE
θ value	1.69304e-06 (rank : 32)	NC score	0.261342 (rank : 279)
Query Neighborhood Hits	368	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

TAF5_HUMAN
θ value	2.21117e-06 (rank : 33)	NC score	0.644738 (rank : 30)
Query Neighborhood Hits	368	Target Neighborhood Hits	352	Shared Neighborhood Hits	203
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5_MOUSE
θ value	2.21117e-06 (rank : 34)	NC score	0.644559 (rank : 31)
Query Neighborhood Hits	368	Target Neighborhood Hits	366	Shared Neighborhood Hits	205
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

U3IP2_HUMAN
θ value	2.21117e-06 (rank : 35)	NC score	0.656698 (rank : 18)
Query Neighborhood Hits	368	Target Neighborhood Hits	307	Shared Neighborhood Hits	197
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

WDR12_MOUSE
θ value	2.21117e-06 (rank : 36)	NC score	0.639672 (rank : 37)
Query Neighborhood Hits	368	Target Neighborhood Hits	301	Shared Neighborhood Hits	193
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WDR17_HUMAN
θ value	2.21117e-06 (rank : 37)	NC score	0.625196 (rank : 63)
Query Neighborhood Hits	368	Target Neighborhood Hits	335	Shared Neighborhood Hits	197
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

U3IP2_MOUSE
θ value	3.77169e-06 (rank : 38)	NC score	0.655925 (rank : 20)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	196
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

TBL1Y_HUMAN
θ value	4.92598e-06 (rank : 39)	NC score	0.619838 (rank : 71)
Query Neighborhood Hits	368	Target Neighborhood Hits	331	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

TBLX_MOUSE
θ value	4.92598e-06 (rank : 40)	NC score	0.618976 (rank : 77)
Query Neighborhood Hits	368	Target Neighborhood Hits	335	Shared Neighborhood Hits	199
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

TBL1R_HUMAN
θ value	8.40245e-06 (rank : 41)	NC score	0.618552 (rank : 79)
Query Neighborhood Hits	368	Target Neighborhood Hits	327	Shared Neighborhood Hits	197
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
θ value	8.40245e-06 (rank : 42)	NC score	0.618120 (rank : 80)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

APAF_MOUSE
θ value	1.09739e-05 (rank : 43)	NC score	0.636207 (rank : 45)
Query Neighborhood Hits	368	Target Neighborhood Hits	343	Shared Neighborhood Hits	205
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

WD51A_MOUSE
θ value	1.09739e-05 (rank : 44)	NC score	0.639989 (rank : 36)
Query Neighborhood Hits	368	Target Neighborhood Hits	342	Shared Neighborhood Hits	204
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

BRWD1_MOUSE
θ value	1.87187e-05 (rank : 45)	NC score	0.580591 (rank : 104)
Query Neighborhood Hits	368	Target Neighborhood Hits	478	Shared Neighborhood Hits	209
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

FBXW2_MOUSE
θ value	1.87187e-05 (rank : 46)	NC score	0.656448 (rank : 19)
Query Neighborhood Hits	368	Target Neighborhood Hits	249	Shared Neighborhood Hits	190
SwissProt Accessions	Q60584	Gene names	Fbxw2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

GBB1_HUMAN
θ value	1.87187e-05 (rank : 47)	NC score	0.627805 (rank : 59)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	P62873, P04697, P04901	Gene names	GNB1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB1_MOUSE
θ value	1.87187e-05 (rank : 48)	NC score	0.627805 (rank : 60)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	P62874, P04697, P04901	Gene names	Gnb1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

UTP15_MOUSE
θ value	1.87187e-05 (rank : 49)	NC score	0.630025 (rank : 56)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	198
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

BRWD1_HUMAN
θ value	2.44474e-05 (rank : 50)	NC score	0.584218 (rank : 102)
Query Neighborhood Hits	368	Target Neighborhood Hits	448	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

FBXW2_HUMAN
θ value	2.44474e-05 (rank : 51)	NC score	0.654629 (rank : 22)
Query Neighborhood Hits	368	Target Neighborhood Hits	260	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

FBXW4_MOUSE
θ value	2.44474e-05 (rank : 52)	NC score	0.530259 (rank : 138)
Query Neighborhood Hits	368	Target Neighborhood Hits	205	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

NLE1_HUMAN
θ value	2.44474e-05 (rank : 53)	NC score	0.640901 (rank : 33)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	205
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

FBXW9_HUMAN
θ value	3.19293e-05 (rank : 54)	NC score	0.582430 (rank : 103)
Query Neighborhood Hits	368	Target Neighborhood Hits	184	Shared Neighborhood Hits	147
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

MORG1_HUMAN
θ value	3.19293e-05 (rank : 55)	NC score	0.657357 (rank : 17)
Query Neighborhood Hits	368	Target Neighborhood Hits	280	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BRX9, Q53FT6	Gene names	MORG1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

PRP19_HUMAN
θ value	3.19293e-05 (rank : 56)	NC score	0.636909 (rank : 43)
Query Neighborhood Hits	368	Target Neighborhood Hits	333	Shared Neighborhood Hits	205
SwissProt Accessions	Q9UMS4	Gene names	PRPF19, NMP200, PRP19
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (hPso4).

TEP1_MOUSE
θ value	3.19293e-05 (rank : 57)	NC score	0.599683 (rank : 94)
Query Neighborhood Hits	368	Target Neighborhood Hits	344	Shared Neighborhood Hits	202
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

WDR31_MOUSE
θ value	3.19293e-05 (rank : 58)	NC score	0.637315 (rank : 40)
Query Neighborhood Hits	368	Target Neighborhood Hits	287	Shared Neighborhood Hits	193
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

UTP15_HUMAN
θ value	4.1701e-05 (rank : 59)	NC score	0.625076 (rank : 64)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	196
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

GBB2_HUMAN
θ value	5.44631e-05 (rank : 60)	NC score	0.619426 (rank : 73)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	P62879, P11016, P54312	Gene names	GNB2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

GBB2_MOUSE
θ value	5.44631e-05 (rank : 61)	NC score	0.619426 (rank : 74)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	P62880, P11016, P54312	Gene names	Gnb2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

PRP19_MOUSE
θ value	5.44631e-05 (rank : 62)	NC score	0.635961 (rank : 47)
Query Neighborhood Hits	368	Target Neighborhood Hits	335	Shared Neighborhood Hits	205
SwissProt Accessions	Q99KP6, Q3TP64, Q8BKZ5, Q8BVQ4	Gene names	Prpf19, Prp19, Snev
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (Nuclear matrix protein SNEV).

SPG16_HUMAN
θ value	5.44631e-05 (rank : 63)	NC score	0.640061 (rank : 35)
Query Neighborhood Hits	368	Target Neighborhood Hits	361	Shared Neighborhood Hits	200
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

TBL1X_HUMAN
θ value	5.44631e-05 (rank : 64)	NC score	0.615827 (rank : 81)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	197
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

WDR57_HUMAN
θ value	7.1131e-05 (rank : 65)	NC score	0.636330 (rank : 44)
Query Neighborhood Hits	368	Target Neighborhood Hits	322	Shared Neighborhood Hits	205
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

WD51B_MOUSE
θ value	9.29e-05 (rank : 66)	NC score	0.632474 (rank : 51)
Query Neighborhood Hits	368	Target Neighborhood Hits	321	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WDR57_MOUSE
θ value	9.29e-05 (rank : 67)	NC score	0.636091 (rank : 46)
Query Neighborhood Hits	368	Target Neighborhood Hits	323	Shared Neighborhood Hits	205
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

FBXW4_HUMAN
θ value	0.000121331 (rank : 68)	NC score	0.512611 (rank : 153)
Query Neighborhood Hits	368	Target Neighborhood Hits	209	Shared Neighborhood Hits	145
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

GBB4_MOUSE
θ value	0.000121331 (rank : 69)	NC score	0.621183 (rank : 69)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	196
SwissProt Accessions	P29387, Q3TJJ1, Q8R475, Q9JHX8	Gene names	Gnb4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

GBLP_HUMAN
θ value	0.000121331 (rank : 70)	NC score	0.648126 (rank : 24)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	204
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
θ value	0.000121331 (rank : 71)	NC score	0.648126 (rank : 25)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	204
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

WD51A_HUMAN
θ value	0.000121331 (rank : 72)	NC score	0.637472 (rank : 39)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	202
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WD51B_HUMAN
θ value	0.000158464 (rank : 73)	NC score	0.632030 (rank : 54)
Query Neighborhood Hits	368	Target Neighborhood Hits	335	Shared Neighborhood Hits	205
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

LIS1_HUMAN
θ value	0.00020696 (rank : 74)	NC score	0.663610 (rank : 14)
Query Neighborhood Hits	368	Target Neighborhood Hits	333	Shared Neighborhood Hits	203
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
θ value	0.00020696 (rank : 75)	NC score	0.663620 (rank : 13)
Query Neighborhood Hits	368	Target Neighborhood Hits	336	Shared Neighborhood Hits	203
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

MORG1_MOUSE
θ value	0.00020696 (rank : 76)	NC score	0.654748 (rank : 21)
Query Neighborhood Hits	368	Target Neighborhood Hits	281	Shared Neighborhood Hits	199
SwissProt Accessions	Q9DAJ4, Q505C2, Q8VEB7, Q99JX9, Q9D235	Gene names	Morg1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

NLE1_MOUSE
θ value	0.00020696 (rank : 77)	NC score	0.636967 (rank : 42)
Query Neighborhood Hits	368	Target Neighborhood Hits	332	Shared Neighborhood Hits	204
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

ZF106_HUMAN
θ value	0.00020696 (rank : 78)	NC score	0.523929 (rank : 142)
Query Neighborhood Hits	368	Target Neighborhood Hits	470	Shared Neighborhood Hits	159
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

SPG16_MOUSE
θ value	0.000270298 (rank : 79)	NC score	0.633596 (rank : 49)
Query Neighborhood Hits	368	Target Neighborhood Hits	377	Shared Neighborhood Hits	196
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

ZF106_MOUSE
θ value	0.000270298 (rank : 80)	NC score	0.521988 (rank : 146)
Query Neighborhood Hits	368	Target Neighborhood Hits	472	Shared Neighborhood Hits	166
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

GBB4_HUMAN
θ value	0.00035302 (rank : 81)	NC score	0.619111 (rank : 76)
Query Neighborhood Hits	368	Target Neighborhood Hits	288	Shared Neighborhood Hits	195
SwissProt Accessions	Q9HAV0	Gene names	GNB4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

FBXW8_HUMAN
θ value	0.000461057 (rank : 82)	NC score	0.394772 (rank : 208)
Query Neighborhood Hits	368	Target Neighborhood Hits	192	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

GBB3_MOUSE
θ value	0.000602161 (rank : 83)	NC score	0.621487 (rank : 68)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	197
SwissProt Accessions	Q61011	Gene names	Gnb3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

FAN_HUMAN
θ value	0.000786445 (rank : 84)	NC score	0.532036 (rank : 136)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	197
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

NUP43_MOUSE
θ value	0.000786445 (rank : 85)	NC score	0.401696 (rank : 206)
Query Neighborhood Hits	368	Target Neighborhood Hits	193	Shared Neighborhood Hits	142
SwissProt Accessions	P59235	Gene names	Nup43
Domain Architecture
Description	Nucleoporin Nup43.

WDR47_HUMAN
θ value	0.000786445 (rank : 86)	NC score	0.605728 (rank : 91)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	179
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR47_MOUSE
θ value	0.000786445 (rank : 87)	NC score	0.606396 (rank : 89)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	181
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR71_HUMAN
θ value	0.000786445 (rank : 88)	NC score	0.663416 (rank : 15)
Query Neighborhood Hits	368	Target Neighborhood Hits	241	Shared Neighborhood Hits	183
SwissProt Accessions	Q9BRP4, Q4G165, Q53HS9, Q7Z500, Q8TBU6, Q9HAB6	Gene names	WDR71
Domain Architecture	No domain graphic available
Description	WD repeat protein 71 (Protein G-16).

COPA_HUMAN
θ value	0.00102713 (rank : 89)	NC score	0.632370 (rank : 52)
Query Neighborhood Hits	368	Target Neighborhood Hits	297	Shared Neighborhood Hits	196
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

GBB3_HUMAN
θ value	0.00102713 (rank : 90)	NC score	0.622044 (rank : 67)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	197
SwissProt Accessions	P16520, Q9BQC0	Gene names	GNB3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

TRAF7_HUMAN
θ value	0.00102713 (rank : 91)	NC score	0.594792 (rank : 98)
Query Neighborhood Hits	368	Target Neighborhood Hits	482	Shared Neighborhood Hits	192
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	0.00102713 (rank : 92)	NC score	0.596715 (rank : 96)
Query Neighborhood Hits	368	Target Neighborhood Hits	470	Shared Neighborhood Hits	192
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TBL3_HUMAN
θ value	0.00134147 (rank : 93)	NC score	0.653213 (rank : 23)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	195
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

WDR37_MOUSE
θ value	0.00175202 (rank : 94)	NC score	0.631587 (rank : 55)
Query Neighborhood Hits	368	Target Neighborhood Hits	298	Shared Neighborhood Hits	192
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

CSTF1_HUMAN
θ value	0.00228821 (rank : 95)	NC score	0.603942 (rank : 93)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	188
SwissProt Accessions	Q05048	Gene names	CSTF1
Domain Architecture
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

GRWD1_MOUSE
θ value	0.00228821 (rank : 96)	NC score	0.532712 (rank : 134)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	191
SwissProt Accessions	Q810D6, Q922H3	Gene names	Grwd1, A301
Domain Architecture	No domain graphic available
Description	Glutamate-rich WD repeat-containing protein 1 (Protein A301).

WDR24_MOUSE
θ value	0.00228821 (rank : 97)	NC score	0.490527 (rank : 159)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

CSTF1_MOUSE
θ value	0.00298849 (rank : 98)	NC score	0.598870 (rank : 95)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	187
SwissProt Accessions	Q99LC2, Q3UMB8, Q8BJW1, Q9CSU8	Gene names	Cstf1
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

PLAP_HUMAN
θ value	0.00298849 (rank : 99)	NC score	0.624084 (rank : 65)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

WDR31_HUMAN
θ value	0.00298849 (rank : 100)	NC score	0.625385 (rank : 62)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	192
SwissProt Accessions	Q8NA23, Q96EG8	Gene names	WDR31
Domain Architecture
Description	WD repeat protein 31.

WDR61_HUMAN
θ value	0.00298849 (rank : 101)	NC score	0.627817 (rank : 58)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	203
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

STRN3_MOUSE
θ value	0.00390308 (rank : 102)	NC score	0.541009 (rank : 128)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	189
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

STRN_MOUSE
θ value	0.00390308 (rank : 103)	NC score	0.533476 (rank : 133)
Query Neighborhood Hits	368	Target Neighborhood Hits	326	Shared Neighborhood Hits	188
SwissProt Accessions	O55106	Gene names	Strn
Domain Architecture
Description	Striatin.

WDR37_HUMAN
θ value	0.00390308 (rank : 104)	NC score	0.627842 (rank : 57)
Query Neighborhood Hits	368	Target Neighborhood Hits	303	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

FAN_MOUSE
θ value	0.00509761 (rank : 105)	NC score	0.517197 (rank : 150)
Query Neighborhood Hits	368	Target Neighborhood Hits	292	Shared Neighborhood Hits	193
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FBXW8_MOUSE
θ value	0.00509761 (rank : 106)	NC score	0.350936 (rank : 227)
Query Neighborhood Hits	368	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

GBB5_HUMAN
θ value	0.00509761 (rank : 107)	NC score	0.619663 (rank : 72)
Query Neighborhood Hits	368	Target Neighborhood Hits	299	Shared Neighborhood Hits	200
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GRWD1_HUMAN
θ value	0.00509761 (rank : 108)	NC score	0.534785 (rank : 131)
Query Neighborhood Hits	368	Target Neighborhood Hits	297	Shared Neighborhood Hits	191
SwissProt Accessions	Q9BQ67	Gene names	GRWD1, GRWD, WDR28
Domain Architecture
Description	Glutamate-rich WD repeat-containing protein 1.

WDR61_MOUSE
θ value	0.00509761 (rank : 109)	NC score	0.627028 (rank : 61)
Query Neighborhood Hits	368	Target Neighborhood Hits	331	Shared Neighborhood Hits	203
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

GBB5_MOUSE
θ value	0.00665767 (rank : 110)	NC score	0.620032 (rank : 70)
Query Neighborhood Hits	368	Target Neighborhood Hits	298	Shared Neighborhood Hits	200
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

A16L1_HUMAN
θ value	0.00869519 (rank : 111)	NC score	0.572371 (rank : 106)
Query Neighborhood Hits	368	Target Neighborhood Hits	664	Shared Neighborhood Hits	197
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

COPB2_HUMAN
θ value	0.00869519 (rank : 112)	NC score	0.619213 (rank : 75)
Query Neighborhood Hits	368	Target Neighborhood Hits	315	Shared Neighborhood Hits	200
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

COPB2_MOUSE
θ value	0.00869519 (rank : 113)	NC score	0.618975 (rank : 78)
Query Neighborhood Hits	368	Target Neighborhood Hits	315	Shared Neighborhood Hits	200
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

NUP43_HUMAN
θ value	0.00869519 (rank : 114)	NC score	0.389567 (rank : 212)
Query Neighborhood Hits	368	Target Neighborhood Hits	198	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NFH3, Q9H8S0	Gene names	NUP43
Domain Architecture
Description	Nucleoporin Nup43 (p42).

STRN3_HUMAN
θ value	0.00869519 (rank : 115)	NC score	0.542265 (rank : 127)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	193
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

A16L1_MOUSE
θ value	0.0113563 (rank : 116)	NC score	0.558365 (rank : 119)
Query Neighborhood Hits	368	Target Neighborhood Hits	776	Shared Neighborhood Hits	195
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

ETV5_MOUSE
θ value	0.0113563 (rank : 117)	NC score	0.048441 (rank : 354)
Query Neighborhood Hits	368	Target Neighborhood Hits	328	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

GNB1L_HUMAN
θ value	0.0113563 (rank : 118)	NC score	0.543039 (rank : 126)
Query Neighborhood Hits	368	Target Neighborhood Hits	221	Shared Neighborhood Hits	160
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

SMU1_HUMAN
θ value	0.0113563 (rank : 119)	NC score	0.610572 (rank : 84)
Query Neighborhood Hits	368	Target Neighborhood Hits	311	Shared Neighborhood Hits	200
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
θ value	0.0113563 (rank : 120)	NC score	0.610572 (rank : 85)
Query Neighborhood Hits	368	Target Neighborhood Hits	311	Shared Neighborhood Hits	200
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

THOC6_HUMAN
θ value	0.0113563 (rank : 121)	NC score	0.498013 (rank : 158)
Query Neighborhood Hits	368	Target Neighborhood Hits	223	Shared Neighborhood Hits	172
SwissProt Accessions	Q86W42, Q8NBR1, Q9BTV9	Gene names	THOC6, WDR58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

WDFY1_HUMAN
θ value	0.0113563 (rank : 122)	NC score	0.463397 (rank : 172)
Query Neighborhood Hits	368	Target Neighborhood Hits	305	Shared Neighborhood Hits	182
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

PLAP_MOUSE
θ value	0.0148317 (rank : 123)	NC score	0.623031 (rank : 66)
Query Neighborhood Hits	368	Target Neighborhood Hits	261	Shared Neighborhood Hits	188
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

RBBP5_HUMAN
θ value	0.0148317 (rank : 124)	NC score	0.470019 (rank : 170)
Query Neighborhood Hits	368	Target Neighborhood Hits	372	Shared Neighborhood Hits	161
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

WDR53_MOUSE
θ value	0.0148317 (rank : 125)	NC score	0.523529 (rank : 144)
Query Neighborhood Hits	368	Target Neighborhood Hits	254	Shared Neighborhood Hits	175
SwissProt Accessions	Q9DB94	Gene names	Wdr53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

WSB1_HUMAN
θ value	0.0148317 (rank : 126)	NC score	0.596672 (rank : 97)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

WSB2_HUMAN
θ value	0.0148317 (rank : 127)	NC score	0.606893 (rank : 87)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	199
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

DIAP1_MOUSE
θ value	0.0193708 (rank : 128)	NC score	0.045396 (rank : 358)
Query Neighborhood Hits	368	Target Neighborhood Hits	839	Shared Neighborhood Hits	36
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

ETV5_HUMAN
θ value	0.0193708 (rank : 129)	NC score	0.042710 (rank : 361)
Query Neighborhood Hits	368	Target Neighborhood Hits	181	Shared Neighborhood Hits	23
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

WDR53_HUMAN
θ value	0.0193708 (rank : 130)	NC score	0.527731 (rank : 139)
Query Neighborhood Hits	368	Target Neighborhood Hits	251	Shared Neighborhood Hits	175
SwissProt Accessions	Q7Z5U6	Gene names	WDR53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

WSB2_MOUSE
θ value	0.0193708 (rank : 131)	NC score	0.605251 (rank : 92)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	199
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

AAMP_HUMAN
θ value	0.0252991 (rank : 132)	NC score	0.637207 (rank : 41)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

PRP17_HUMAN
θ value	0.0252991 (rank : 133)	NC score	0.606017 (rank : 90)
Query Neighborhood Hits	368	Target Neighborhood Hits	297	Shared Neighborhood Hits	194
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

PRP17_MOUSE
θ value	0.0252991 (rank : 134)	NC score	0.606588 (rank : 88)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	193
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

PWP1_MOUSE
θ value	0.0252991 (rank : 135)	NC score	0.536803 (rank : 130)
Query Neighborhood Hits	368	Target Neighborhood Hits	278	Shared Neighborhood Hits	182
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

STRN_HUMAN
θ value	0.0252991 (rank : 136)	NC score	0.526950 (rank : 140)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	190
SwissProt Accessions	O43815, Q9NP38	Gene names	STRN
Domain Architecture
Description	Striatin.

WDR41_MOUSE
θ value	0.0252991 (rank : 137)	NC score	0.479988 (rank : 164)
Query Neighborhood Hits	368	Target Neighborhood Hits	209	Shared Neighborhood Hits	155
SwissProt Accessions	Q3UDP0, Q8C4F1, Q8C8K5	Gene names	Wdr41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

WDR7_HUMAN
θ value	0.0252991 (rank : 138)	NC score	0.414380 (rank : 197)
Query Neighborhood Hits	368	Target Neighborhood Hits	244	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

ERCC8_MOUSE
θ value	0.0330416 (rank : 139)	NC score	0.565876 (rank : 111)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	185
SwissProt Accessions	Q8CFD5, Q3U066, Q8VDC4, Q9CWK7	Gene names	Ercc8, Ckn1, Csa
Domain Architecture	No domain graphic available
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog).

KI21A_HUMAN
θ value	0.0330416 (rank : 140)	NC score	0.275950 (rank : 266)
Query Neighborhood Hits	368	Target Neighborhood Hits	1543	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

WDR72_HUMAN
θ value	0.0330416 (rank : 141)	NC score	0.348091 (rank : 230)
Query Neighborhood Hits	368	Target Neighborhood Hits	167	Shared Neighborhood Hits	123
SwissProt Accessions	Q3MJ13, Q7Z3I3, Q8N8X2	Gene names	WDR72
Domain Architecture	No domain graphic available
Description	WD repeat protein 72.

KI21B_MOUSE
θ value	0.0431538 (rank : 142)	NC score	0.288796 (rank : 262)
Query Neighborhood Hits	368	Target Neighborhood Hits	997	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

PRP4_HUMAN
θ value	0.0431538 (rank : 143)	NC score	0.632253 (rank : 53)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	202
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

PRP4_MOUSE
θ value	0.0431538 (rank : 144)	NC score	0.632629 (rank : 50)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	202
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

WDR7_MOUSE
θ value	0.0431538 (rank : 145)	NC score	0.417991 (rank : 193)
Query Neighborhood Hits	368	Target Neighborhood Hits	226	Shared Neighborhood Hits	159
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

CO3A1_MOUSE
θ value	0.0563607 (rank : 146)	NC score	0.024373 (rank : 408)
Query Neighborhood Hits	368	Target Neighborhood Hits	466	Shared Neighborhood Hits	27
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COR1A_MOUSE
θ value	0.0563607 (rank : 147)	NC score	0.342702 (rank : 232)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	158
SwissProt Accessions	O89053, Q7TMU0, Q9R1Y8, Q9R288	Gene names	Coro1a, Coro1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

STRN4_MOUSE
θ value	0.0563607 (rank : 148)	NC score	0.538181 (rank : 129)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	197
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

THOC6_MOUSE
θ value	0.0563607 (rank : 149)	NC score	0.465469 (rank : 171)
Query Neighborhood Hits	368	Target Neighborhood Hits	199	Shared Neighborhood Hits	157
SwissProt Accessions	Q5U4D9	Gene names	Thoc6, Wdr58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

WDR1_HUMAN
θ value	0.0563607 (rank : 150)	NC score	0.575521 (rank : 105)
Query Neighborhood Hits	368	Target Neighborhood Hits	292	Shared Neighborhood Hits	192
SwissProt Accessions	O75083, O75313, Q8N6E5, Q9UG05, Q9UG78, Q9UQE0	Gene names	WDR1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1).

WDR6_HUMAN
θ value	0.0563607 (rank : 151)	NC score	0.443662 (rank : 183)
Query Neighborhood Hits	368	Target Neighborhood Hits	193	Shared Neighborhood Hits	141
SwissProt Accessions	Q9NNW5, Q9UF63	Gene names	WDR6
Domain Architecture
Description	WD repeat protein 6.

CDC20_HUMAN
θ value	0.0736092 (rank : 152)	NC score	0.567762 (rank : 108)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	194
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

IASPP_MOUSE
θ value	0.0736092 (rank : 153)	NC score	0.033543 (rank : 380)
Query Neighborhood Hits	368	Target Neighborhood Hits	1024	Shared Neighborhood Hits	74
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KI21B_HUMAN
θ value	0.0736092 (rank : 154)	NC score	0.292951 (rank : 259)
Query Neighborhood Hits	368	Target Neighborhood Hits	1017	Shared Neighborhood Hits	203
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

COR1A_HUMAN
θ value	0.0961366 (rank : 155)	NC score	0.337632 (rank : 237)
Query Neighborhood Hits	368	Target Neighborhood Hits	240	Shared Neighborhood Hits	161
SwissProt Accessions	P31146	Gene names	CORO1A, CORO1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

ERCC8_HUMAN
θ value	0.0961366 (rank : 156)	NC score	0.562660 (rank : 115)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	186
SwissProt Accessions	Q13216, Q6FHX5, Q96GB9	Gene names	ERCC8, CKN1, CSA
Domain Architecture
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA).

GNB1L_MOUSE
θ value	0.0961366 (rank : 157)	NC score	0.564207 (rank : 114)
Query Neighborhood Hits	368	Target Neighborhood Hits	231	Shared Neighborhood Hits	169
SwissProt Accessions	Q9EQ15, Q8R1F3, Q9CWP2, Q9D3Y1	Gene names	Gnb1l, Estm55, Wdr14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF).

WASL_MOUSE
θ value	0.0961366 (rank : 158)	NC score	0.053279 (rank : 351)
Query Neighborhood Hits	368	Target Neighborhood Hits	339	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

KI21A_MOUSE
θ value	0.125558 (rank : 159)	NC score	0.274750 (rank : 268)
Query Neighborhood Hits	368	Target Neighborhood Hits	1317	Shared Neighborhood Hits	203
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

WDR18_HUMAN
θ value	0.125558 (rank : 160)	NC score	0.566213 (rank : 110)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	183
SwissProt Accessions	Q9BV38, O60390, Q9BWR2	Gene names	WDR18
Domain Architecture
Description	WD repeat protein 18.

WDR1_MOUSE
θ value	0.125558 (rank : 161)	NC score	0.566987 (rank : 109)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	191
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

WDR65_HUMAN
θ value	0.125558 (rank : 162)	NC score	0.507305 (rank : 155)
Query Neighborhood Hits	368	Target Neighborhood Hits	238	Shared Neighborhood Hits	170
SwissProt Accessions	Q96MR6, Q5TAI0	Gene names	WDR65
Domain Architecture	No domain graphic available
Description	WD repeat protein 65.

DAAM1_HUMAN
θ value	0.163984 (rank : 163)	NC score	0.042063 (rank : 363)
Query Neighborhood Hits	368	Target Neighborhood Hits	483	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

FA47A_HUMAN
θ value	0.163984 (rank : 164)	NC score	0.056555 (rank : 346)
Query Neighborhood Hits	368	Target Neighborhood Hits	451	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

MEP50_MOUSE
θ value	0.163984 (rank : 165)	NC score	0.504859 (rank : 156)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	182
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

STRN4_HUMAN
θ value	0.163984 (rank : 166)	NC score	0.534316 (rank : 132)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	195
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

WDR33_HUMAN
θ value	0.163984 (rank : 167)	NC score	0.522644 (rank : 145)
Query Neighborhood Hits	368	Target Neighborhood Hits	638	Shared Neighborhood Hits	229
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

CS007_HUMAN
θ value	0.21417 (rank : 168)	NC score	0.045202 (rank : 359)
Query Neighborhood Hits	368	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

PREB_MOUSE
θ value	0.21417 (rank : 169)	NC score	0.320862 (rank : 246)
Query Neighborhood Hits	368	Target Neighborhood Hits	156	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WUQ2, Q9QZ99	Gene names	Preb, Sec12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

WSB1_MOUSE
θ value	0.21417 (rank : 170)	NC score	0.585550 (rank : 101)
Query Neighborhood Hits	368	Target Neighborhood Hits	313	Shared Neighborhood Hits	198
SwissProt Accessions	O54927	Gene names	Wsb1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1).

COR1C_HUMAN
θ value	0.279714 (rank : 171)	NC score	0.323745 (rank : 244)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	160
SwissProt Accessions	Q9ULV4, Q9NSK5	Gene names	CORO1C, CRNN4
Domain Architecture
Description	Coronin-1C (Coronin-3) (hCRNN4).

COR1C_MOUSE
θ value	0.279714 (rank : 172)	NC score	0.324151 (rank : 243)
Query Neighborhood Hits	368	Target Neighborhood Hits	251	Shared Neighborhood Hits	161
SwissProt Accessions	Q9WUM4, Q8VCQ5	Gene names	Coro1c
Domain Architecture
Description	Coronin-1C (Coronin-3).

CS007_MOUSE
θ value	0.279714 (rank : 173)	NC score	0.046178 (rank : 357)
Query Neighborhood Hits	368	Target Neighborhood Hits	464	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DIAP1_HUMAN
θ value	0.279714 (rank : 174)	NC score	0.045030 (rank : 360)
Query Neighborhood Hits	368	Target Neighborhood Hits	784	Shared Neighborhood Hits	37
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

FZR_HUMAN
θ value	0.279714 (rank : 175)	NC score	0.560995 (rank : 117)
Query Neighborhood Hits	368	Target Neighborhood Hits	279	Shared Neighborhood Hits	191
SwissProt Accessions	Q9UM11, O75869, Q86U66, Q96NW8, Q9UI96, Q9ULH8, Q9UM10, Q9UNQ1, Q9Y2T8	Gene names	FZR1, CDH1, FYR, FZR, KIAA1242
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1) (CDC20-like protein 1).

FZR_MOUSE
θ value	0.279714 (rank : 176)	NC score	0.561532 (rank : 116)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	193
SwissProt Accessions	Q9R1K5	Gene names	Fzr1, Fyr, Fzr
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog).

WDR46_MOUSE
θ value	0.279714 (rank : 177)	NC score	0.223341 (rank : 290)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WDR48_HUMAN
θ value	0.279714 (rank : 178)	NC score	0.615448 (rank : 82)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	198
SwissProt Accessions	Q8TAF3, Q63HJ2, Q658Y1, Q8N3Z1, Q9NSK8, Q9P279	Gene names	WDR48, KIAA1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48 (WD repeat endosomal protein) (p80).

WDR48_MOUSE
θ value	0.279714 (rank : 179)	NC score	0.613172 (rank : 83)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	198
SwissProt Accessions	Q8BH57, Q80TD4, Q80XI0, Q8BRM0, Q8CBK0, Q922Z9, Q9CRR1, Q9CSL0	Gene names	Wdr48, Kiaa1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48.

BOP1_MOUSE
θ value	0.365318 (rank : 180)	NC score	0.446028 (rank : 181)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	177
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

CAF1B_MOUSE
θ value	0.365318 (rank : 181)	NC score	0.523767 (rank : 143)
Query Neighborhood Hits	368	Target Neighborhood Hits	385	Shared Neighborhood Hits	200
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CO3A1_HUMAN
θ value	0.365318 (rank : 182)	NC score	0.021855 (rank : 417)
Query Neighborhood Hits	368	Target Neighborhood Hits	452	Shared Neighborhood Hits	28
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

EPN1_HUMAN
θ value	0.365318 (rank : 183)	NC score	0.028960 (rank : 393)
Query Neighborhood Hits	368	Target Neighborhood Hits	206	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

IF32_HUMAN
θ value	0.365318 (rank : 184)	NC score	0.552464 (rank : 122)
Query Neighborhood Hits	368	Target Neighborhood Hits	239	Shared Neighborhood Hits	176
SwissProt Accessions	Q13347	Gene names	EIF3S2, TRIP1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

IF32_MOUSE
θ value	0.365318 (rank : 185)	NC score	0.553520 (rank : 121)
Query Neighborhood Hits	368	Target Neighborhood Hits	239	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QZD9	Gene names	Eif3s2, Trip1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

PELP1_HUMAN
θ value	0.365318 (rank : 186)	NC score	0.041701 (rank : 364)
Query Neighborhood Hits	368	Target Neighborhood Hits	596	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

WDR16_HUMAN
θ value	0.365318 (rank : 187)	NC score	0.560624 (rank : 118)
Query Neighborhood Hits	368	Target Neighborhood Hits	275	Shared Neighborhood Hits	191
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

GP108_MOUSE
θ value	0.47712 (rank : 188)	NC score	0.029258 (rank : 391)
Query Neighborhood Hits	368	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

RBBP6_HUMAN
θ value	0.47712 (rank : 189)	NC score	0.023525 (rank : 413)
Query Neighborhood Hits	368	Target Neighborhood Hits	1135	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

WDR41_HUMAN
θ value	0.47712 (rank : 190)	NC score	0.452353 (rank : 174)
Query Neighborhood Hits	368	Target Neighborhood Hits	208	Shared Neighborhood Hits	165
SwissProt Accessions	Q9HAD4, Q7Z792, Q8IWG3, Q8IXA9, Q8NDA7, Q9NV62	Gene names	WDR41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

WNK2_HUMAN
θ value	0.47712 (rank : 191)	NC score	-0.000799 (rank : 489)
Query Neighborhood Hits	368	Target Neighborhood Hits	1407	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

YLPM1_HUMAN
θ value	0.47712 (rank : 192)	NC score	0.049133 (rank : 353)
Query Neighborhood Hits	368	Target Neighborhood Hits	670	Shared Neighborhood Hits	53
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

BAT2_HUMAN
θ value	0.62314 (rank : 193)	NC score	0.042271 (rank : 362)
Query Neighborhood Hits	368	Target Neighborhood Hits	931	Shared Neighborhood Hits	74
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RBBP6_MOUSE
θ value	0.62314 (rank : 194)	NC score	0.028991 (rank : 392)
Query Neighborhood Hits	368	Target Neighborhood Hits	1014	Shared Neighborhood Hits	41
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

WDR54_HUMAN
θ value	0.62314 (rank : 195)	NC score	0.140156 (rank : 318)
Query Neighborhood Hits	368	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H977, Q53H85, Q86V45	Gene names	WDR54
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

ARI1A_HUMAN
θ value	0.813845 (rank : 196)	NC score	0.037701 (rank : 366)
Query Neighborhood Hits	368	Target Neighborhood Hits	787	Shared Neighborhood Hits	74
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CA156_MOUSE
θ value	0.813845 (rank : 197)	NC score	0.034843 (rank : 377)
Query Neighborhood Hits	368	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZ09, Q810I8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf156 homolog.

CAF1B_HUMAN
θ value	0.813845 (rank : 198)	NC score	0.520932 (rank : 147)
Query Neighborhood Hits	368	Target Neighborhood Hits	345	Shared Neighborhood Hits	193
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

HCN2_HUMAN
θ value	0.813845 (rank : 199)	NC score	0.014130 (rank : 447)
Query Neighborhood Hits	368	Target Neighborhood Hits	369	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

LTBP4_MOUSE
θ value	0.813845 (rank : 200)	NC score	0.002944 (rank : 482)
Query Neighborhood Hits	368	Target Neighborhood Hits	607	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

PRD15_HUMAN
θ value	0.813845 (rank : 201)	NC score	-0.005917 (rank : 498)
Query Neighborhood Hits	368	Target Neighborhood Hits	805	Shared Neighborhood Hits	11
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

PREB_HUMAN
θ value	0.813845 (rank : 202)	NC score	0.329473 (rank : 242)
Query Neighborhood Hits	368	Target Neighborhood Hits	163	Shared Neighborhood Hits	129
SwissProt Accessions	Q9HCU5, Q9UH94	Gene names	PREB, SEC12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

WDR54_MOUSE
θ value	0.813845 (rank : 203)	NC score	0.196249 (rank : 295)
Query Neighborhood Hits	368	Target Neighborhood Hits	96	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

CBL_HUMAN
θ value	1.06291 (rank : 204)	NC score	0.025749 (rank : 403)
Query Neighborhood Hits	368	Target Neighborhood Hits	353	Shared Neighborhood Hits	31
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

LYST_HUMAN
θ value	1.06291 (rank : 205)	NC score	0.276178 (rank : 265)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	133
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

MAGC1_HUMAN
θ value	1.06291 (rank : 206)	NC score	0.014850 (rank : 444)
Query Neighborhood Hits	368	Target Neighborhood Hits	431	Shared Neighborhood Hits	34
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PCLO_MOUSE
θ value	1.06291 (rank : 207)	NC score	0.031459 (rank : 386)
Query Neighborhood Hits	368	Target Neighborhood Hits	2275	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SPHK2_MOUSE
θ value	1.06291 (rank : 208)	NC score	0.025309 (rank : 405)
Query Neighborhood Hits	368	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

STRAP_HUMAN
θ value	1.06291 (rank : 209)	NC score	0.589091 (rank : 99)
Query Neighborhood Hits	368	Target Neighborhood Hits	272	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y3F4, Q9UQC8	Gene names	STRAP, MAWD, UNRIP
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein) (WD-40 repeat protein PT-WD) (MAP activator with WD repeats).

STRAP_MOUSE
θ value	1.06291 (rank : 210)	NC score	0.589053 (rank : 100)
Query Neighborhood Hits	368	Target Neighborhood Hits	279	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Z1Z2	Gene names	Strap, Unrip
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein).

WDR23_HUMAN
θ value	1.06291 (rank : 211)	NC score	0.520748 (rank : 148)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	180
SwissProt Accessions	Q8TEB1, Q86U00, Q86U39, Q8NDN2, Q9H2J0, Q9H3A3, Q9H5C9	Gene names	WDR23
Domain Architecture
Description	WD repeat protein 23.

WDR23_MOUSE
θ value	1.06291 (rank : 212)	NC score	0.526477 (rank : 141)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	181
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

WDR35_HUMAN
θ value	1.06291 (rank : 213)	NC score	0.122038 (rank : 323)
Query Neighborhood Hits	368	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

WDR46_HUMAN
θ value	1.06291 (rank : 214)	NC score	0.243314 (rank : 286)
Query Neighborhood Hits	368	Target Neighborhood Hits	147	Shared Neighborhood Hits	95
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

CRTC1_HUMAN
θ value	1.38821 (rank : 215)	NC score	0.030637 (rank : 387)
Query Neighborhood Hits	368	Target Neighborhood Hits	319	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ENAH_MOUSE
θ value	1.38821 (rank : 216)	NC score	0.021953 (rank : 416)
Query Neighborhood Hits	368	Target Neighborhood Hits	919	Shared Neighborhood Hits	51
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FMN2_HUMAN
θ value	1.38821 (rank : 217)	NC score	0.036938 (rank : 368)
Query Neighborhood Hits	368	Target Neighborhood Hits	484	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FOXN1_MOUSE
θ value	1.38821 (rank : 218)	NC score	0.018234 (rank : 434)
Query Neighborhood Hits	368	Target Neighborhood Hits	300	Shared Neighborhood Hits	46
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

GRIN2_HUMAN
θ value	1.38821 (rank : 219)	NC score	0.036753 (rank : 369)
Query Neighborhood Hits	368	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

HES7_MOUSE
θ value	1.38821 (rank : 220)	NC score	0.026074 (rank : 400)
Query Neighborhood Hits	368	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MEP50_HUMAN
θ value	1.38821 (rank : 221)	NC score	0.489476 (rank : 160)
Query Neighborhood Hits	368	Target Neighborhood Hits	268	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BQA1, Q96GK4, Q9BWY3	Gene names	WDR77, MEP50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

RBBP7_HUMAN
θ value	1.38821 (rank : 222)	NC score	0.479298 (rank : 166)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	191
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_MOUSE
θ value	1.38821 (rank : 223)	NC score	0.479379 (rank : 165)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	191
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RNC_HUMAN
θ value	1.38821 (rank : 224)	NC score	0.032590 (rank : 382)
Query Neighborhood Hits	368	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

SC24A_MOUSE
θ value	1.38821 (rank : 225)	NC score	0.036725 (rank : 370)
Query Neighborhood Hits	368	Target Neighborhood Hits	394	Shared Neighborhood Hits	68
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SF01_HUMAN
θ value	1.38821 (rank : 226)	NC score	0.036308 (rank : 372)
Query Neighborhood Hits	368	Target Neighborhood Hits	287	Shared Neighborhood Hits	24
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	1.38821 (rank : 227)	NC score	0.036056 (rank : 375)
Query Neighborhood Hits	368	Target Neighborhood Hits	240	Shared Neighborhood Hits	18
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SH22A_HUMAN
θ value	1.38821 (rank : 228)	NC score	0.023941 (rank : 411)
Query Neighborhood Hits	368	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SMR3A_HUMAN
θ value	1.38821 (rank : 229)	NC score	0.046536 (rank : 356)
Query Neighborhood Hits	368	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

WASF4_HUMAN
θ value	1.38821 (rank : 230)	NC score	0.024831 (rank : 406)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WDR16_MOUSE
θ value	1.38821 (rank : 231)	NC score	0.557706 (rank : 120)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	189
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

WDR39_HUMAN
θ value	1.38821 (rank : 232)	NC score	0.565661 (rank : 112)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	187
SwissProt Accessions	O76071	Gene names	WDR39, CIAO1
Domain Architecture
Description	WD repeat protein 39 (Ciao 1 protein).

CD5R2_MOUSE
θ value	1.81305 (rank : 233)	NC score	0.029650 (rank : 390)
Query Neighborhood Hits	368	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

COR1B_MOUSE
θ value	1.81305 (rank : 234)	NC score	0.304816 (rank : 253)
Query Neighborhood Hits	368	Target Neighborhood Hits	235	Shared Neighborhood Hits	152
SwissProt Accessions	Q9WUM3, Q3UEB1, Q9CVA2	Gene names	Coro1b
Domain Architecture
Description	Coronin-1B (Coronin-2).

LYST_MOUSE
θ value	1.81305 (rank : 235)	NC score	0.258261 (rank : 280)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	134
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

PEX7_MOUSE
θ value	1.81305 (rank : 236)	NC score	0.570902 (rank : 107)
Query Neighborhood Hits	368	Target Neighborhood Hits	279	Shared Neighborhood Hits	188
SwissProt Accessions	P97865	Gene names	Pex7
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

PRD16_HUMAN
θ value	1.81305 (rank : 237)	NC score	-0.005913 (rank : 497)
Query Neighborhood Hits	368	Target Neighborhood Hits	832	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

RBBP4_HUMAN
θ value	1.81305 (rank : 238)	NC score	0.481777 (rank : 162)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	191
SwissProt Accessions	Q09028, P31149, Q53H02, Q96BV9	Gene names	RBBP4, RBAP48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

RBBP4_MOUSE
θ value	1.81305 (rank : 239)	NC score	0.481753 (rank : 163)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	189
SwissProt Accessions	Q60972	Gene names	Rbbp4, Rbap48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

SFPQ_HUMAN
θ value	1.81305 (rank : 240)	NC score	0.017056 (rank : 438)
Query Neighborhood Hits	368	Target Neighborhood Hits	986	Shared Neighborhood Hits	44
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SMDF_HUMAN
θ value	1.81305 (rank : 241)	NC score	0.027005 (rank : 397)
Query Neighborhood Hits	368	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

YLPM1_MOUSE
θ value	1.81305 (rank : 242)	NC score	0.037471 (rank : 367)
Query Neighborhood Hits	368	Target Neighborhood Hits	505	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZN295_HUMAN
θ value	1.81305 (rank : 243)	NC score	-0.003993 (rank : 494)
Query Neighborhood Hits	368	Target Neighborhood Hits	847	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

AAK1_HUMAN
θ value	2.36792 (rank : 244)	NC score	-0.003077 (rank : 492)
Query Neighborhood Hits	368	Target Neighborhood Hits	1077	Shared Neighborhood Hits	42
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AB1IP_HUMAN
θ value	2.36792 (rank : 245)	NC score	0.020774 (rank : 424)
Query Neighborhood Hits	368	Target Neighborhood Hits	213	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

CPSF6_HUMAN
θ value	2.36792 (rank : 246)	NC score	0.032447 (rank : 384)
Query Neighborhood Hits	368	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	2.36792 (rank : 247)	NC score	0.032455 (rank : 383)
Query Neighborhood Hits	368	Target Neighborhood Hits	356	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CTDP1_HUMAN
θ value	2.36792 (rank : 248)	NC score	0.028683 (rank : 394)
Query Neighborhood Hits	368	Target Neighborhood Hits	416	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

FOXB2_MOUSE
θ value	2.36792 (rank : 249)	NC score	0.007343 (rank : 474)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

MLL2_HUMAN
θ value	2.36792 (rank : 250)	NC score	0.019551 (rank : 429)
Query Neighborhood Hits	368	Target Neighborhood Hits	1788	Shared Neighborhood Hits	93
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NEDD1_HUMAN
θ value	2.36792 (rank : 251)	NC score	0.471894 (rank : 169)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	171
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

NEDD1_MOUSE
θ value	2.36792 (rank : 252)	NC score	0.474105 (rank : 168)
Query Neighborhood Hits	368	Target Neighborhood Hits	281	Shared Neighborhood Hits	162
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

PELP1_MOUSE
θ value	2.36792 (rank : 253)	NC score	0.048170 (rank : 355)
Query Neighborhood Hits	368	Target Neighborhood Hits	709	Shared Neighborhood Hits	67
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PWP1_HUMAN
θ value	2.36792 (rank : 254)	NC score	0.511270 (rank : 154)
Query Neighborhood Hits	368	Target Neighborhood Hits	261	Shared Neighborhood Hits	177
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

SF3A1_MOUSE
θ value	2.36792 (rank : 255)	NC score	0.020803 (rank : 423)
Query Neighborhood Hits	368	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SMCA4_HUMAN
θ value	2.36792 (rank : 256)	NC score	0.012275 (rank : 454)
Query Neighborhood Hits	368	Target Neighborhood Hits	597	Shared Neighborhood Hits	36
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

TAF4_HUMAN
θ value	2.36792 (rank : 257)	NC score	0.025399 (rank : 404)
Query Neighborhood Hits	368	Target Neighborhood Hits	687	Shared Neighborhood Hits	41
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

WDR18_MOUSE
θ value	2.36792 (rank : 258)	NC score	0.550164 (rank : 124)
Query Neighborhood Hits	368	Target Neighborhood Hits	239	Shared Neighborhood Hits	176
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

ZN683_HUMAN
θ value	2.36792 (rank : 259)	NC score	-0.006421 (rank : 499)
Query Neighborhood Hits	368	Target Neighborhood Hits	750	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZ20, Q5T141, Q5T146, Q5T147, Q5T149, Q8NEN4	Gene names	ZNF683
Domain Architecture	No domain graphic available
Description	Zinc finger protein 683.

ABL1_MOUSE
θ value	3.0926 (rank : 260)	NC score	-0.008565 (rank : 502)
Query Neighborhood Hits	368	Target Neighborhood Hits	1178	Shared Neighborhood Hits	20
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CBL_MOUSE
θ value	3.0926 (rank : 261)	NC score	0.022561 (rank : 415)
Query Neighborhood Hits	368	Target Neighborhood Hits	426	Shared Neighborhood Hits	39
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CD5R2_HUMAN
θ value	3.0926 (rank : 262)	NC score	0.029965 (rank : 389)
Query Neighborhood Hits	368	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q13319, Q4ZFW6	Gene names	CDK5R2, NCK5AI
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

CORO6_MOUSE
θ value	3.0926 (rank : 263)	NC score	0.341877 (rank : 233)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	161
SwissProt Accessions	Q920M5, Q920M3, Q920M4	Gene names	Coro6
Domain Architecture	No domain graphic available
Description	Coronin-6 (Clipin E).

FMNL_HUMAN
θ value	3.0926 (rank : 264)	NC score	0.039305 (rank : 365)
Query Neighborhood Hits	368	Target Neighborhood Hits	529	Shared Neighborhood Hits	41
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

IRX3_HUMAN
θ value	3.0926 (rank : 265)	NC score	0.015735 (rank : 440)
Query Neighborhood Hits	368	Target Neighborhood Hits	342	Shared Neighborhood Hits	11
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

KCNC3_MOUSE
θ value	3.0926 (rank : 266)	NC score	0.005445 (rank : 477)
Query Neighborhood Hits	368	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

LCP2_HUMAN
θ value	3.0926 (rank : 267)	NC score	0.032081 (rank : 385)
Query Neighborhood Hits	368	Target Neighborhood Hits	531	Shared Neighborhood Hits	60
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MBD6_HUMAN
θ value	3.0926 (rank : 268)	NC score	0.027615 (rank : 395)
Query Neighborhood Hits	368	Target Neighborhood Hits	349	Shared Neighborhood Hits	29
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

RBM16_HUMAN
θ value	3.0926 (rank : 269)	NC score	0.025766 (rank : 402)
Query Neighborhood Hits	368	Target Neighborhood Hits	300	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RP3A_HUMAN
θ value	3.0926 (rank : 270)	NC score	0.010197 (rank : 463)
Query Neighborhood Hits	368	Target Neighborhood Hits	305	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TESK1_MOUSE
θ value	3.0926 (rank : 271)	NC score	-0.007794 (rank : 501)
Query Neighborhood Hits	368	Target Neighborhood Hits	862	Shared Neighborhood Hits	10
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

ZN553_HUMAN
θ value	3.0926 (rank : 272)	NC score	-0.007704 (rank : 500)
Query Neighborhood Hits	368	Target Neighborhood Hits	760	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

BAT2_MOUSE
θ value	4.03905 (rank : 273)	NC score	0.035846 (rank : 376)
Query Neighborhood Hits	368	Target Neighborhood Hits	947	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BOP1_HUMAN
θ value	4.03905 (rank : 274)	NC score	0.410115 (rank : 199)
Query Neighborhood Hits	368	Target Neighborhood Hits	257	Shared Neighborhood Hits	167
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

CO7A1_HUMAN
θ value	4.03905 (rank : 275)	NC score	0.010394 (rank : 461)
Query Neighborhood Hits	368	Target Neighborhood Hits	807	Shared Neighborhood Hits	45
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DMXL2_HUMAN
θ value	4.03905 (rank : 276)	NC score	0.323540 (rank : 245)
Query Neighborhood Hits	368	Target Neighborhood Hits	374	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

EP300_HUMAN
θ value	4.03905 (rank : 277)	NC score	0.036118 (rank : 373)
Query Neighborhood Hits	368	Target Neighborhood Hits	821	Shared Neighborhood Hits	68
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

IQEC2_MOUSE
θ value	4.03905 (rank : 278)	NC score	0.010650 (rank : 460)
Query Neighborhood Hits	368	Target Neighborhood Hits	417	Shared Neighborhood Hits	29
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IRX3_MOUSE
θ value	4.03905 (rank : 279)	NC score	0.012711 (rank : 452)
Query Neighborhood Hits	368	Target Neighborhood Hits	303	Shared Neighborhood Hits	10
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

JIP3_MOUSE
θ value	4.03905 (rank : 280)	NC score	0.012554 (rank : 453)
Query Neighborhood Hits	368	Target Neighborhood Hits	759	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

KI13B_HUMAN
θ value	4.03905 (rank : 281)	NC score	0.018749 (rank : 433)
Query Neighborhood Hits	368	Target Neighborhood Hits	492	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

PDC6I_MOUSE
θ value	4.03905 (rank : 282)	NC score	0.020696 (rank : 426)
Query Neighborhood Hits	368	Target Neighborhood Hits	275	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

RIN3_HUMAN
θ value	4.03905 (rank : 283)	NC score	0.018223 (rank : 435)
Query Neighborhood Hits	368	Target Neighborhood Hits	227	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RTN4_HUMAN
θ value	4.03905 (rank : 284)	NC score	0.013345 (rank : 451)
Query Neighborhood Hits	368	Target Neighborhood Hits	357	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SF3A2_HUMAN
θ value	4.03905 (rank : 285)	NC score	0.025816 (rank : 401)
Query Neighborhood Hits	368	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SMRC1_MOUSE
θ value	4.03905 (rank : 286)	NC score	0.013744 (rank : 449)
Query Neighborhood Hits	368	Target Neighborhood Hits	459	Shared Neighborhood Hits	24
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SYT5_HUMAN
θ value	4.03905 (rank : 287)	NC score	0.005352 (rank : 478)
Query Neighborhood Hits	368	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

TARA_HUMAN
θ value	4.03905 (rank : 288)	NC score	0.015281 (rank : 443)
Query Neighborhood Hits	368	Target Neighborhood Hits	1626	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WASP_MOUSE
θ value	4.03905 (rank : 289)	NC score	0.036681 (rank : 371)
Query Neighborhood Hits	368	Target Neighborhood Hits	223	Shared Neighborhood Hits	24
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ZN219_HUMAN
θ value	4.03905 (rank : 290)	NC score	-0.004672 (rank : 495)
Query Neighborhood Hits	368	Target Neighborhood Hits	876	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

COKA1_HUMAN
θ value	5.27518 (rank : 291)	NC score	0.008438 (rank : 471)
Query Neighborhood Hits	368	Target Neighborhood Hits	403	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

COR1B_HUMAN
θ value	5.27518 (rank : 292)	NC score	0.304263 (rank : 254)
Query Neighborhood Hits	368	Target Neighborhood Hits	239	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BR76	Gene names	CORO1B
Domain Architecture
Description	Coronin-1B (Coronin-2).

DAAM2_HUMAN
θ value	5.27518 (rank : 293)	NC score	0.033008 (rank : 381)
Query Neighborhood Hits	368	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DGKK_HUMAN
θ value	5.27518 (rank : 294)	NC score	0.010205 (rank : 462)
Query Neighborhood Hits	368	Target Neighborhood Hits	378	Shared Neighborhood Hits	17
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

GFC1_HUMAN
θ value	5.27518 (rank : 295)	NC score	0.019251 (rank : 431)
Query Neighborhood Hits	368	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

HNRL1_HUMAN
θ value	5.27518 (rank : 296)	NC score	0.021380 (rank : 420)
Query Neighborhood Hits	368	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
θ value	5.27518 (rank : 297)	NC score	0.021219 (rank : 421)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

HXB4_MOUSE
θ value	5.27518 (rank : 298)	NC score	-0.002440 (rank : 491)
Query Neighborhood Hits	368	Target Neighborhood Hits	375	Shared Neighborhood Hits	9
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

KIF1C_MOUSE
θ value	5.27518 (rank : 299)	NC score	0.019195 (rank : 432)
Query Neighborhood Hits	368	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

MAST4_HUMAN
θ value	5.27518 (rank : 300)	NC score	-0.003694 (rank : 493)
Query Neighborhood Hits	368	Target Neighborhood Hits	1804	Shared Neighborhood Hits	79
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MEIS2_MOUSE
θ value	5.27518 (rank : 301)	NC score	0.007757 (rank : 472)
Query Neighborhood Hits	368	Target Neighborhood Hits	208	Shared Neighborhood Hits	14
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

RAPH1_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.020721 (rank : 425)
Query Neighborhood Hits	368	Target Neighborhood Hits	593	Shared Neighborhood Hits	46
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

AKAP2_HUMAN
θ value	6.88961 (rank : 303)	NC score	0.013465 (rank : 450)
Query Neighborhood Hits	368	Target Neighborhood Hits	507	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ATN1_HUMAN
θ value	6.88961 (rank : 304)	NC score	0.019783 (rank : 427)
Query Neighborhood Hits	368	Target Neighborhood Hits	676	Shared Neighborhood Hits	40
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAT3_HUMAN
θ value	6.88961 (rank : 305)	NC score	0.022933 (rank : 414)
Query Neighborhood Hits	368	Target Neighborhood Hits	490	Shared Neighborhood Hits	61
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BICD1_HUMAN
θ value	6.88961 (rank : 306)	NC score	0.001555 (rank : 486)
Query Neighborhood Hits	368	Target Neighborhood Hits	844	Shared Neighborhood Hits	21
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BRD4_MOUSE
θ value	6.88961 (rank : 307)	NC score	0.021450 (rank : 419)
Query Neighborhood Hits	368	Target Neighborhood Hits	845	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BSN_MOUSE
θ value	6.88961 (rank : 308)	NC score	0.030143 (rank : 388)
Query Neighborhood Hits	368	Target Neighborhood Hits	2057	Shared Neighborhood Hits	127
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CMTA2_MOUSE
θ value	6.88961 (rank : 309)	NC score	0.010030 (rank : 464)
Query Neighborhood Hits	368	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CORO7_HUMAN
θ value	6.88961 (rank : 310)	NC score	0.392721 (rank : 209)
Query Neighborhood Hits	368	Target Neighborhood Hits	315	Shared Neighborhood Hits	187
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

DMWD_MOUSE
θ value	6.88961 (rank : 311)	NC score	0.341672 (rank : 234)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	153
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

DMXL1_MOUSE
θ value	6.88961 (rank : 312)	NC score	0.299544 (rank : 258)
Query Neighborhood Hits	368	Target Neighborhood Hits	257	Shared Neighborhood Hits	161
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

HDAC7_HUMAN
θ value	6.88961 (rank : 313)	NC score	0.005548 (rank : 476)
Query Neighborhood Hits	368	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

HNF3G_HUMAN
θ value	6.88961 (rank : 314)	NC score	0.003882 (rank : 479)
Query Neighborhood Hits	368	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	P55318, Q9UMW9	Gene names	FOXA3, HNF3G, TCF3G
Domain Architecture
Description	Hepatocyte nuclear factor 3-gamma (HNF-3G) (Forkhead box protein A3) (Fork head-related protein FKH H3).

HRX_HUMAN
θ value	6.88961 (rank : 315)	NC score	0.011367 (rank : 459)
Query Neighborhood Hits	368	Target Neighborhood Hits	825	Shared Neighborhood Hits	45
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

KCNA5_HUMAN
θ value	6.88961 (rank : 316)	NC score	0.002624 (rank : 483)
Query Neighborhood Hits	368	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

PTN23_HUMAN
θ value	6.88961 (rank : 317)	NC score	0.011806 (rank : 457)
Query Neighborhood Hits	368	Target Neighborhood Hits	646	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	6.88961 (rank : 318)	NC score	0.014713 (rank : 445)
Query Neighborhood Hits	368	Target Neighborhood Hits	726	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RP3A_MOUSE
θ value	6.88961 (rank : 319)	NC score	0.013758 (rank : 448)
Query Neighborhood Hits	368	Target Neighborhood Hits	510	Shared Neighborhood Hits	56
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RXRB_HUMAN
θ value	6.88961 (rank : 320)	NC score	0.000213 (rank : 488)
Query Neighborhood Hits	368	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

SAM68_HUMAN
θ value	6.88961 (rank : 321)	NC score	0.017948 (rank : 436)
Query Neighborhood Hits	368	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SF3A2_MOUSE
θ value	6.88961 (rank : 322)	NC score	0.024317 (rank : 410)
Query Neighborhood Hits	368	Target Neighborhood Hits	247	Shared Neighborhood Hits	26
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFR15_HUMAN
θ value	6.88961 (rank : 323)	NC score	0.026423 (rank : 399)
Query Neighborhood Hits	368	Target Neighborhood Hits	368	Shared Neighborhood Hits	28
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SMR1_MOUSE
θ value	6.88961 (rank : 324)	NC score	0.021512 (rank : 418)
Query Neighborhood Hits	368	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

TBX6_MOUSE
θ value	6.88961 (rank : 325)	NC score	0.003337 (rank : 481)
Query Neighborhood Hits	368	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

WDFY2_HUMAN
θ value	6.88961 (rank : 326)	NC score	0.420523 (rank : 191)
Query Neighborhood Hits	368	Target Neighborhood Hits	332	Shared Neighborhood Hits	185
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
θ value	6.88961 (rank : 327)	NC score	0.415736 (rank : 195)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	185
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDFY3_HUMAN
θ value	6.88961 (rank : 328)	NC score	0.275261 (rank : 267)
Query Neighborhood Hits	368	Target Neighborhood Hits	348	Shared Neighborhood Hits	166
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
θ value	6.88961 (rank : 329)	NC score	0.273701 (rank : 270)
Query Neighborhood Hits	368	Target Neighborhood Hits	332	Shared Neighborhood Hits	170
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDR13_HUMAN
θ value	6.88961 (rank : 330)	NC score	0.378516 (rank : 218)
Query Neighborhood Hits	368	Target Neighborhood Hits	186	Shared Neighborhood Hits	139
SwissProt Accessions	Q9H1Z4, Q9BUL7, Q9NWW4	Gene names	WDR13
Domain Architecture
Description	WD repeat protein 13.

WNK4_HUMAN
θ value	6.88961 (rank : 331)	NC score	-0.005137 (rank : 496)
Query Neighborhood Hits	368	Target Neighborhood Hits	1043	Shared Neighborhood Hits	26
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ANR11_HUMAN
θ value	8.99809 (rank : 332)	NC score	0.002014 (rank : 485)
Query Neighborhood Hits	368	Target Neighborhood Hits	1289	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CABIN_HUMAN
θ value	8.99809 (rank : 333)	NC score	0.024500 (rank : 407)
Query Neighborhood Hits	368	Target Neighborhood Hits	490	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CCNK_MOUSE
θ value	8.99809 (rank : 334)	NC score	0.009535 (rank : 467)
Query Neighborhood Hits	368	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CIC_MOUSE
θ value	8.99809 (rank : 335)	NC score	0.012192 (rank : 455)
Query Neighborhood Hits	368	Target Neighborhood Hits	742	Shared Neighborhood Hits	61
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CK036_HUMAN
θ value	8.99809 (rank : 336)	NC score	0.020820 (rank : 422)
Query Neighborhood Hits	368	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q2M3A8, Q6TF48, Q8N7R8, Q8N9X7	Gene names	C11orf36
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf36.

CROCC_HUMAN
θ value	8.99809 (rank : 337)	NC score	-0.001343 (rank : 490)
Query Neighborhood Hits	368	Target Neighborhood Hits	1409	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CXXC6_HUMAN
θ value	8.99809 (rank : 338)	NC score	0.014604 (rank : 446)
Query Neighborhood Hits	368	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

DOT1L_HUMAN
θ value	8.99809 (rank : 339)	NC score	0.015548 (rank : 441)
Query Neighborhood Hits	368	Target Neighborhood Hits	660	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EMAL2_HUMAN
θ value	8.99809 (rank : 340)	NC score	0.406280 (rank : 202)
Query Neighborhood Hits	368	Target Neighborhood Hits	217	Shared Neighborhood Hits	155
SwissProt Accessions	O95834, Q9UG50	Gene names	EML2, EMAP2, EMAPL2
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2).

ENV2_MOUSE
θ value	8.99809 (rank : 341)	NC score	0.009455 (rank : 468)
Query Neighborhood Hits	368	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

EPN1_MOUSE
θ value	8.99809 (rank : 342)	NC score	0.019585 (rank : 428)
Query Neighborhood Hits	368	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

FMNL_MOUSE
θ value	8.99809 (rank : 343)	NC score	0.036060 (rank : 374)
Query Neighborhood Hits	368	Target Neighborhood Hits	428	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GSCR1_HUMAN
θ value	8.99809 (rank : 344)	NC score	0.019428 (rank : 430)
Query Neighborhood Hits	368	Target Neighborhood Hits	674	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HD_HUMAN
θ value	8.99809 (rank : 345)	NC score	0.008684 (rank : 470)
Query Neighborhood Hits	368	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

I17RC_HUMAN
θ value	8.99809 (rank : 346)	NC score	0.011370 (rank : 458)
Query Neighborhood Hits	368	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NAC3, Q6UVY3, Q6UWD4, Q8NFS1, Q9BR97	Gene names	IL17RC
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor C precursor (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor-like protein) (IL-17RL) (Interleukin-17 receptor homolog) (IL17Rhom).

IRX5_HUMAN
θ value	8.99809 (rank : 347)	NC score	0.010016 (rank : 465)
Query Neighborhood Hits	368	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

JARD2_MOUSE
θ value	8.99809 (rank : 348)	NC score	0.007673 (rank : 473)
Query Neighborhood Hits	368	Target Neighborhood Hits	169	Shared Neighborhood Hits	9
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

K0310_HUMAN
θ value	8.99809 (rank : 349)	NC score	0.023752 (rank : 412)
Query Neighborhood Hits	368	Target Neighborhood Hits	420	Shared Neighborhood Hits	48
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

NID2_HUMAN
θ value	8.99809 (rank : 350)	NC score	0.000777 (rank : 487)
Query Neighborhood Hits	368	Target Neighborhood Hits	456	Shared Neighborhood Hits	30
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

PAPPA_HUMAN
θ value	8.99809 (rank : 351)	NC score	0.003848 (rank : 480)
Query Neighborhood Hits	368	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PI5PA_HUMAN
θ value	8.99809 (rank : 352)	NC score	0.026984 (rank : 398)
Query Neighborhood Hits	368	Target Neighborhood Hits	749	Shared Neighborhood Hits	89
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRP2_MOUSE
θ value	8.99809 (rank : 353)	NC score	0.024372 (rank : 409)
Query Neighborhood Hits	368	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RANB3_HUMAN
θ value	8.99809 (rank : 354)	NC score	0.011955 (rank : 456)
Query Neighborhood Hits	368	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

RERE_MOUSE
θ value	8.99809 (rank : 355)	NC score	0.015469 (rank : 442)
Query Neighborhood Hits	368	Target Neighborhood Hits	785	Shared Neighborhood Hits	54
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RFWD2_HUMAN
θ value	8.99809 (rank : 356)	NC score	0.447922 (rank : 179)
Query Neighborhood Hits	368	Target Neighborhood Hits	518	Shared Neighborhood Hits	178
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	8.99809 (rank : 357)	NC score	0.447011 (rank : 180)
Query Neighborhood Hits	368	Target Neighborhood Hits	535	Shared Neighborhood Hits	178
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

SAM68_MOUSE
θ value	8.99809 (rank : 358)	NC score	0.016000 (rank : 439)
Query Neighborhood Hits	368	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SOX9_MOUSE
θ value	8.99809 (rank : 359)	NC score	0.002049 (rank : 484)
Query Neighborhood Hits	368	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

TCGAP_HUMAN
θ value	8.99809 (rank : 360)	NC score	0.027099 (rank : 396)
Query Neighborhood Hits	368	Target Neighborhood Hits	872	Shared Neighborhood Hits	92
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TITIN_HUMAN
θ value	8.99809 (rank : 361)	NC score	-0.010321 (rank : 503)
Query Neighborhood Hits	368	Target Neighborhood Hits	2923	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WASF2_MOUSE
θ value	8.99809 (rank : 362)	NC score	0.017378 (rank : 437)
Query Neighborhood Hits	368	Target Neighborhood Hits	315	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASL_HUMAN
θ value	8.99809 (rank : 363)	NC score	0.033804 (rank : 379)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	8.99809 (rank : 364)	NC score	0.033986 (rank : 378)
Query Neighborhood Hits	368	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WDR13_MOUSE
θ value	8.99809 (rank : 365)	NC score	0.370016 (rank : 224)
Query Neighborhood Hits	368	Target Neighborhood Hits	195	Shared Neighborhood Hits	143
SwissProt Accessions	Q91V09	Gene names	Wdr13
Domain Architecture
Description	WD repeat protein 13.

XYLT1_HUMAN
θ value	8.99809 (rank : 366)	NC score	0.006994 (rank : 475)
Query Neighborhood Hits	368	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

ZCHC8_HUMAN
θ value	8.99809 (rank : 367)	NC score	0.009561 (rank : 466)
Query Neighborhood Hits	368	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZY4, Q7L2P6, Q8N2K5, Q96SK7, Q9NSS2, Q9NSS3	Gene names	ZCCHC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

ZMYM3_HUMAN
θ value	8.99809 (rank : 368)	NC score	0.009168 (rank : 469)
Query Neighborhood Hits	368	Target Neighborhood Hits	223	Shared Neighborhood Hits	16
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

AAAS_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.251331 (rank : 283)
Query Neighborhood Hits	368	Target Neighborhood Hits	154	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NRG9, Q9NWI6, Q9UG19	Gene names	AAAS, ADRACALA
Domain Architecture
Description	Aladin (Adracalin).

AAAS_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.210690 (rank : 292)
Query Neighborhood Hits	368	Target Neighborhood Hits	144	Shared Neighborhood Hits	104
SwissProt Accessions	P58742, Q544M6	Gene names	Aaas
Domain Architecture
Description	Aladin (Adracalin).

AHI1_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.391564 (rank : 210)
Query Neighborhood Hits	368	Target Neighborhood Hits	537	Shared Neighborhood Hits	175
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AHI1_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.409685 (rank : 200)
Query Neighborhood Hits	368	Target Neighborhood Hits	496	Shared Neighborhood Hits	177
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ARC1A_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.156803 (rank : 308)
Query Neighborhood Hits	368	Target Neighborhood Hits	113	Shared Neighborhood Hits	79
SwissProt Accessions	Q92747, Q7Z5U8, Q86WU5, Q8IXQ0	Gene names	ARPC1A, SOP2L
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein).

ARC1A_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.154032 (rank : 312)
Query Neighborhood Hits	368	Target Neighborhood Hits	120	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0Q6, Q3UL75	Gene names	Arpc1a, Sid329
Domain Architecture	No domain graphic available
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329).

ARC1B_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.205470 (rank : 293)
Query Neighborhood Hits	368	Target Neighborhood Hits	148	Shared Neighborhood Hits	109
SwissProt Accessions	O15143, Q9BU00	Gene names	ARPC1B, ARC41
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

ARC1B_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.192230 (rank : 298)
Query Neighborhood Hits	368	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WV32	Gene names	Arpc1b
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

BRWD2_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.152991 (rank : 313)
Query Neighborhood Hits	368	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BZH6, Q5VWA1	Gene names	BRWD2, WDR11
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 2 (WD repeat protein 11).

BUB3_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.431799 (rank : 188)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	155
SwissProt Accessions	O43684, O43685	Gene names	BUB3
Domain Architecture
Description	Mitotic checkpoint protein BUB3.

BUB3_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.422493 (rank : 190)
Query Neighborhood Hits	368	Target Neighborhood Hits	199	Shared Neighborhood Hits	155
SwissProt Accessions	Q9WVA3, P97397	Gene names	Bub3
Domain Architecture
Description	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5).

CDC20_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.550638 (rank : 123)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	191
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

CIR1A_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.267225 (rank : 273)
Query Neighborhood Hits	368	Target Neighborhood Hits	158	Shared Neighborhood Hits	107
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

CIR1A_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.265417 (rank : 274)
Query Neighborhood Hits	368	Target Neighborhood Hits	155	Shared Neighborhood Hits	104
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

COR2A_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.301563 (rank : 256)
Query Neighborhood Hits	368	Target Neighborhood Hits	214	Shared Neighborhood Hits	144
SwissProt Accessions	Q92828, Q92829, Q9BWS5	Gene names	CORO2A, IR10, WDR2
Domain Architecture
Description	Coronin-2A (WD repeat-containing protein 2) (IR10).

COR2A_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.286378 (rank : 263)
Query Neighborhood Hits	368	Target Neighborhood Hits	204	Shared Neighborhood Hits	132
SwissProt Accessions	Q8C0P5, Q3U6H8, Q8BW42	Gene names	Coro2a
Domain Architecture	No domain graphic available
Description	Coronin-2A.

COR2B_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.337046 (rank : 238)
Query Neighborhood Hits	368	Target Neighborhood Hits	233	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UQ03, O94767, Q8TAN1	Gene names	CORO2B, KIAA0925
Domain Architecture
Description	Coronin-2B (Coronin-like protein C) (ClipinC) (Protein FC96).

COR2B_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.334648 (rank : 239)
Query Neighborhood Hits	368	Target Neighborhood Hits	235	Shared Neighborhood Hits	164
SwissProt Accessions	Q8BH44, Q6P5U9	Gene names	Coro2b
Domain Architecture	No domain graphic available
Description	Coronin-2B.

CORO7_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.407984 (rank : 201)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	191
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

DC1I1_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.120585 (rank : 324)
Query Neighborhood Hits	368	Target Neighborhood Hits	183	Shared Neighborhood Hits	82
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

DC1I1_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.117371 (rank : 325)
Query Neighborhood Hits	368	Target Neighborhood Hits	206	Shared Neighborhood Hits	86
SwissProt Accessions	O88485, O88486	Gene names	Dync1i1, Dnci1, Dncic1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

DC1I2_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.149909 (rank : 315)
Query Neighborhood Hits	368	Target Neighborhood Hits	201	Shared Neighborhood Hits	96
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

DC1I2_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.154063 (rank : 311)
Query Neighborhood Hits	368	Target Neighborhood Hits	209	Shared Neighborhood Hits	98
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

DDB2_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.301068 (rank : 257)
Query Neighborhood Hits	368	Target Neighborhood Hits	175	Shared Neighborhood Hits	118
SwissProt Accessions	Q92466, Q76E54, Q76E55, Q76E56, Q76E57	Gene names	DDB2
Domain Architecture
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2) (DDB p48 subunit) (DDBb) (UV-damaged DNA-binding protein 2) (UV-DDB 2).

DDB2_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.305772 (rank : 252)
Query Neighborhood Hits	368	Target Neighborhood Hits	175	Shared Neighborhood Hits	123
SwissProt Accessions	Q99J79	Gene names	Ddb2
Domain Architecture	No domain graphic available
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2).

DMXL1_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.253680 (rank : 282)
Query Neighborhood Hits	368	Target Neighborhood Hits	259	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

DNAI1_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.158543 (rank : 305)
Query Neighborhood Hits	368	Target Neighborhood Hits	148	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UI46, Q9UEZ8	Gene names	DNAI1
Domain Architecture
Description	Dynein intermediate chain 1, axonemal (Axonemal dynein intermediate chain 1).

DNAI2_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.161842 (rank : 303)
Query Neighborhood Hits	368	Target Neighborhood Hits	156	Shared Neighborhood Hits	84
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

EMAL1_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.375740 (rank : 220)
Query Neighborhood Hits	368	Target Neighborhood Hits	214	Shared Neighborhood Hits	155
SwissProt Accessions	O00423	Gene names	EML1, EMAP1, EMAPL, EMAPL1
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1).

EMAL4_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.375736 (rank : 221)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	168
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

FBX16_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.097512 (rank : 330)
Query Neighborhood Hits	368	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FBX16_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.090987 (rank : 333)
Query Neighborhood Hits	368	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

FBXW5_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.238214 (rank : 287)
Query Neighborhood Hits	368	Target Neighborhood Hits	156	Shared Neighborhood Hits	100
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBXW5_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.249806 (rank : 284)
Query Neighborhood Hits	368	Target Neighborhood Hits	159	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

GEMI5_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.415416 (rank : 196)
Query Neighborhood Hits	368	Target Neighborhood Hits	362	Shared Neighborhood Hits	191
SwissProt Accessions	Q8TEQ6, Q8WWV4, Q969W4, Q9H9K3, Q9UFI5	Gene names	GEMIN5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

GEMI5_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.423503 (rank : 189)
Query Neighborhood Hits	368	Target Neighborhood Hits	424	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

HIRA_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.448806 (rank : 178)
Query Neighborhood Hits	368	Target Neighborhood Hits	279	Shared Neighborhood Hits	173
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

HIRA_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.450466 (rank : 176)
Query Neighborhood Hits	368	Target Neighborhood Hits	274	Shared Neighborhood Hits	175
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

IF122_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.434203 (rank : 187)
Query Neighborhood Hits	368	Target Neighborhood Hits	244	Shared Neighborhood Hits	166
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

IF140_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.067260 (rank : 342)
Query Neighborhood Hits	368	Target Neighborhood Hits	111	Shared Neighborhood Hits	47
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

IFT80_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.311801 (rank : 250)
Query Neighborhood Hits	368	Target Neighborhood Hits	195	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P2H3	Gene names	IFT80, KIAA1374, WDR56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

IFT80_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.315145 (rank : 248)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	132
SwissProt Accessions	Q8K057	Gene names	Ift80, Wdr56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

LRBA_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.152004 (rank : 314)
Query Neighborhood Hits	368	Target Neighborhood Hits	196	Shared Neighborhood Hits	91
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

NBEAL_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.232401 (rank : 288)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	139
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

NBEA_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.157512 (rank : 307)
Query Neighborhood Hits	368	Target Neighborhood Hits	186	Shared Neighborhood Hits	106
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.156649 (rank : 309)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	104
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

NOL10_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.051159 (rank : 352)
Query Neighborhood Hits	368	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NUP37_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.302797 (rank : 255)
Query Neighborhood Hits	368	Target Neighborhood Hits	153	Shared Neighborhood Hits	116
SwissProt Accessions	Q8NFH4, Q9H644	Gene names	NUP37
Domain Architecture
Description	Nucleoporin Nup37 (p37).

NUP37_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.312862 (rank : 249)
Query Neighborhood Hits	368	Target Neighborhood Hits	159	Shared Neighborhood Hits	124
SwissProt Accessions	Q9CWU9	Gene names	Nup37
Domain Architecture
Description	Nucleoporin Nup37.

PEX7_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.565498 (rank : 113)
Query Neighborhood Hits	368	Target Neighborhood Hits	275	Shared Neighborhood Hits	187
SwissProt Accessions	O00628	Gene names	PEX7, PTS2R
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

PI3R4_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.140891 (rank : 317)
Query Neighborhood Hits	368	Target Neighborhood Hits	534	Shared Neighborhood Hits	114
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

PI3R4_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.134742 (rank : 319)
Query Neighborhood Hits	368	Target Neighborhood Hits	535	Shared Neighborhood Hits	113
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

PPWD1_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.128481 (rank : 320)
Query Neighborhood Hits	368	Target Neighborhood Hits	136	Shared Neighborhood Hits	90
SwissProt Accessions	Q96BP3, Q15002, Q7KZ89	Gene names	PPWD1, KIAA0073
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PPWD1_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.124000 (rank : 321)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	89
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

RAE1L_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.438607 (rank : 186)
Query Neighborhood Hits	368	Target Neighborhood Hits	222	Shared Neighborhood Hits	166
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

RAE1L_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.440642 (rank : 184)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

RPTOR_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.175479 (rank : 302)
Query Neighborhood Hits	368	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

RPTOR_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.159256 (rank : 304)
Query Neighborhood Hits	368	Target Neighborhood Hits	129	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

SEC13_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.379841 (rank : 214)
Query Neighborhood Hits	368	Target Neighborhood Hits	199	Shared Neighborhood Hits	138
SwissProt Accessions	P55735, Q9BRM6, Q9BUG7	Gene names	SEC13L1, SEC13R
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

SEC13_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.386439 (rank : 213)
Query Neighborhood Hits	368	Target Neighborhood Hits	195	Shared Neighborhood Hits	136
SwissProt Accessions	Q9D1M0, Q99M12, Q9D712	Gene names	Sec13l1
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

SEH1L_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.333165 (rank : 241)
Query Neighborhood Hits	368	Target Neighborhood Hits	145	Shared Neighborhood Hits	103
SwissProt Accessions	Q96EE3, Q8NFU6, Q96MH3, Q9C069	Gene names	SEH1L, SEC13L, SEH1
Domain Architecture
Description	Nucleoporin SEH1-like (SEC13-like protein).

STB5L_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.086683 (rank : 335)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STB5L_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.087064 (rank : 334)
Query Neighborhood Hits	368	Target Neighborhood Hits	138	Shared Neighborhood Hits	77
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STTP1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.391476 (rank : 211)
Query Neighborhood Hits	368	Target Neighborhood Hits	232	Shared Neighborhood Hits	168
SwissProt Accessions	Q6IA86, Q53GZ0, Q687Y8, Q8N5C2, Q96GV4, Q96PI7, Q9H9N0, Q9NV81	Gene names	STATIP1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1) (SHINC-2).

STTP1_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.396969 (rank : 207)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	172
SwissProt Accessions	Q91WG4, Q3TIH5, Q3TIT0, Q8CBW6, Q9ESY7	Gene names	Statip1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1).

STXB5_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.092689 (rank : 332)
Query Neighborhood Hits	368	Target Neighborhood Hits	167	Shared Neighborhood Hits	96
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

STXB5_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.083329 (rank : 337)
Query Neighborhood Hits	368	Target Neighborhood Hits	161	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

TBL2_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.460174 (rank : 173)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y4P3, Q9UQE2	Gene names	TBL2, WBSCR13
Domain Architecture
Description	Transducin beta-like 2 protein (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosome region 13 protein).

TBL2_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.438778 (rank : 185)
Query Neighborhood Hits	368	Target Neighborhood Hits	221	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R099	Gene names	Tbl2
Domain Architecture
Description	Transducin beta-like 2 protein.

TF3C2_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.064063 (rank : 343)
Query Neighborhood Hits	368	Target Neighborhood Hits	168	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TF3C2_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.072439 (rank : 340)
Query Neighborhood Hits	368	Target Neighborhood Hits	165	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

THOC3_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.532148 (rank : 135)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	191
SwissProt Accessions	Q96J01	Gene names	THOC3
Domain Architecture
Description	THO complex subunit 3 (Tho3) (TEX1 homolog).

THOC3_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.530946 (rank : 137)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	191
SwissProt Accessions	Q8VE80, Q9CWI8	Gene names	Thoc3
Domain Architecture
Description	THO complex subunit 3 (Tho3).

TLE1_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.367830 (rank : 226)
Query Neighborhood Hits	368	Target Neighborhood Hits	485	Shared Neighborhood Hits	218
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TLE1_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.369088 (rank : 225)
Query Neighborhood Hits	368	Target Neighborhood Hits	491	Shared Neighborhood Hits	229
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TLE2_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.379148 (rank : 216)
Query Neighborhood Hits	368	Target Neighborhood Hits	321	Shared Neighborhood Hits	193
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

TLE2_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.378371 (rank : 219)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	189
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

TLE3_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.373022 (rank : 223)
Query Neighborhood Hits	368	Target Neighborhood Hits	385	Shared Neighborhood Hits	200
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

TLE3_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.374759 (rank : 222)
Query Neighborhood Hits	368	Target Neighborhood Hits	378	Shared Neighborhood Hits	197
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

TLE4_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.378881 (rank : 217)
Query Neighborhood Hits	368	Target Neighborhood Hits	477	Shared Neighborhood Hits	217
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.379159 (rank : 215)
Query Neighborhood Hits	368	Target Neighborhood Hits	482	Shared Neighborhood Hits	218
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE6_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.157628 (rank : 306)
Query Neighborhood Hits	368	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

TLE6_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.273990 (rank : 269)
Query Neighborhood Hits	368	Target Neighborhood Hits	178	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

TR95_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.072986 (rank : 339)
Query Neighborhood Hits	368	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PGF3	Gene names	Thrap5
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

TSCC1_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.264569 (rank : 275)
Query Neighborhood Hits	368	Target Neighborhood Hits	160	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K0G5	Gene names	Tssc1
Domain Architecture	No domain graphic available
Description	Protein TSSC1.

TSSC1_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.256940 (rank : 281)
Query Neighborhood Hits	368	Target Neighborhood Hits	157	Shared Neighborhood Hits	104
SwissProt Accessions	Q53HC9, O43179, Q53S19, Q53SG2	Gene names	TSSC1
Domain Architecture	No domain graphic available
Description	Protein TSSC1 (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein) (Tumor-suppressing STF cDNA 1 protein).

TULP4_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.084237 (rank : 336)
Query Neighborhood Hits	368	Target Neighborhood Hits	426	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TULP4_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.074275 (rank : 338)
Query Neighborhood Hits	368	Target Neighborhood Hits	247	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

UTP18_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.248292 (rank : 285)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

UTP18_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.200500 (rank : 294)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q5SSI6	Gene names	Utp18, Wdr50
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

WD21A_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.282077 (rank : 264)
Query Neighborhood Hits	368	Target Neighborhood Hits	136	Shared Neighborhood Hits	114
SwissProt Accessions	Q8WV16, Q86U31, Q96K22, Q9Y4P5	Gene names	WDR21A, WDR21
Domain Architecture
Description	WD repeat protein 21A.

WD21C_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.350166 (rank : 229)
Query Neighborhood Hits	368	Target Neighborhood Hits	157	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

WDHD1_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.444320 (rank : 182)
Query Neighborhood Hits	368	Target Neighborhood Hits	342	Shared Neighborhood Hits	171
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

WDHD1_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.450408 (rank : 177)
Query Neighborhood Hits	368	Target Neighborhood Hits	414	Shared Neighborhood Hits	183
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

WDR19_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.055676 (rank : 347)
Query Neighborhood Hits	368	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NEZ3, Q8N5B4, Q9H5S0, Q9HCD4	Gene names	WDR19, KIAA1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

WDR19_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.054162 (rank : 350)
Query Neighborhood Hits	368	Target Neighborhood Hits	83	Shared Neighborhood Hits	41
SwissProt Accessions	Q3UGF1, Q6ZPK8, Q80VQ6, Q8C794, Q8K3R5	Gene names	Wdr19, Kiaa1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

WDR20_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.320660 (rank : 247)
Query Neighborhood Hits	368	Target Neighborhood Hits	249	Shared Neighborhood Hits	141
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

WDR20_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.334110 (rank : 240)
Query Neighborhood Hits	368	Target Neighborhood Hits	217	Shared Neighborhood Hits	144
SwissProt Accessions	Q9D5R2	Gene names	Wdr20
Domain Architecture
Description	WD repeat protein 20.

WDR22_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.416540 (rank : 194)
Query Neighborhood Hits	368	Target Neighborhood Hits	328	Shared Neighborhood Hits	174
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

WDR22_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.418655 (rank : 192)
Query Neighborhood Hits	368	Target Neighborhood Hits	302	Shared Neighborhood Hits	167
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

WDR24_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.350167 (rank : 228)
Query Neighborhood Hits	368	Target Neighborhood Hits	247	Shared Neighborhood Hits	152
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WDR26_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.515363 (rank : 151)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	191
SwissProt Accessions	Q9H7D7, Q86UY4	Gene names	WDR26
Domain Architecture
Description	WD repeat protein 26.

WDR26_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.513912 (rank : 152)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	191
SwissProt Accessions	Q8C6G8, Q8C4F3, Q8VDZ6	Gene names	Wdr26
Domain Architecture
Description	WD repeat protein 26.

WDR34_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.095261 (rank : 331)
Query Neighborhood Hits	368	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q96EX3, Q5VXV4, Q9BV46	Gene names	WDR34
Domain Architecture
Description	WD repeat protein 34.

WDR34_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.107616 (rank : 327)
Query Neighborhood Hits	368	Target Neighborhood Hits	105	Shared Neighborhood Hits	63
SwissProt Accessions	Q5U4F6	Gene names	Wdr34
Domain Architecture	No domain graphic available
Description	WD repeat protein 34.

WDR35_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.098027 (rank : 329)
Query Neighborhood Hits	368	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

WDR36_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.546316 (rank : 125)
Query Neighborhood Hits	368	Target Neighborhood Hits	274	Shared Neighborhood Hits	188
SwissProt Accessions	Q8NI36, Q8N1Q2	Gene names	WDR36
Domain Architecture
Description	WD repeat protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP).

WDR43_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.477753 (rank : 167)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	144
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

WDR49_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.519378 (rank : 149)
Query Neighborhood Hits	368	Target Neighborhood Hits	214	Shared Neighborhood Hits	162
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

WDR4_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.261754 (rank : 277)
Query Neighborhood Hits	368	Target Neighborhood Hits	145	Shared Neighborhood Hits	108
SwissProt Accessions	P57081, Q9HCR3	Gene names	WDR4
Domain Architecture
Description	WD repeat protein 4.

WDR4_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.263184 (rank : 276)
Query Neighborhood Hits	368	Target Neighborhood Hits	136	Shared Neighborhood Hits	103
SwissProt Accessions	Q9EP82	Gene names	Wdr4
Domain Architecture
Description	WD repeat protein 4.

WDR55_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.499033 (rank : 157)
Query Neighborhood Hits	368	Target Neighborhood Hits	231	Shared Neighborhood Hits	168
SwissProt Accessions	Q9H6Y2	Gene names	WDR55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

WDR55_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.488171 (rank : 161)
Query Neighborhood Hits	368	Target Neighborhood Hits	236	Shared Neighborhood Hits	168
SwissProt Accessions	Q9CX97	Gene names	Wdr55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

WDR67_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.189991 (rank : 299)
Query Neighborhood Hits	368	Target Neighborhood Hits	782	Shared Neighborhood Hits	123
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

WDR67_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.232044 (rank : 289)
Query Neighborhood Hits	368	Target Neighborhood Hits	476	Shared Neighborhood Hits	103
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

WDR68_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.186656 (rank : 300)
Query Neighborhood Hits	368	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	P61962, O15491, Q9DAE4	Gene names	WDR68, HAN11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

WDR68_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.186656 (rank : 301)
Query Neighborhood Hits	368	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	P61963, O15491, Q3TMV9, Q9DAE4	Gene names	Wdr68, Han11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

WDR74_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.156313 (rank : 310)
Query Neighborhood Hits	368	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q6RFH5, Q9BRC9, Q9H6X8, Q9NVY2	Gene names	WDR74, NSA1
Domain Architecture	No domain graphic available
Description	WD repeat protein 74 (NOP seven-associated protein 1).

WDR74_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.123510 (rank : 322)
Query Neighborhood Hits	368	Target Neighborhood Hits	70	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VCG3	Gene names	Wdr74
Domain Architecture	No domain graphic available
Description	WD repeat protein 74.

WDR75_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.401901 (rank : 205)
Query Neighborhood Hits	368	Target Neighborhood Hits	193	Shared Neighborhood Hits	134
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

WDR76_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.063314 (rank : 344)
Query Neighborhood Hits	368	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H967	Gene names	WDR76
Domain Architecture	No domain graphic available
Description	WD repeat protein 76.

WDR79_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.411938 (rank : 198)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

WDR79_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.451292 (rank : 175)
Query Neighborhood Hits	368	Target Neighborhood Hits	216	Shared Neighborhood Hits	149
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

WDR81_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.309349 (rank : 251)
Query Neighborhood Hits	368	Target Neighborhood Hits	205	Shared Neighborhood Hits	141
SwissProt Accessions	Q562E7, Q24JP6, Q8N277, Q8N3F3	Gene names	WDR81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

WDR81_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.347273 (rank : 231)
Query Neighborhood Hits	368	Target Neighborhood Hits	228	Shared Neighborhood Hits	158
SwissProt Accessions	Q5ND34, Q3TA90, Q3TUS9, Q6KAR1	Gene names	Wdr81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

WDR85_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.220217 (rank : 291)
Query Neighborhood Hits	368	Target Neighborhood Hits	134	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BTV6, Q96AB7	Gene names	WDR85, C9orf112
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

WDR85_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.142598 (rank : 316)
Query Neighborhood Hits	368	Target Neighborhood Hits	108	Shared Neighborhood Hits	76
SwissProt Accessions	Q9CYU6, Q5RJV7, Q8BIT9	Gene names	Wdr85
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

WDR8_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.114013 (rank : 326)
Query Neighborhood Hits	368	Target Neighborhood Hits	69	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2S5, Q5T0D6, Q9BUH7, Q9NTK7, Q9NX56	Gene names	WDR8
Domain Architecture
Description	WD repeat protein 8.

WDR8_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.107489 (rank : 328)
Query Neighborhood Hits	368	Target Neighborhood Hits	71	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JM98	Gene names	Wdr8, Dd57
Domain Architecture
Description	WD repeat protein 8.

WDTC1_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.405806 (rank : 203)
Query Neighborhood Hits	368	Target Neighborhood Hits	299	Shared Neighborhood Hits	183
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDTC1_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.405210 (rank : 204)
Query Neighborhood Hits	368	Target Neighborhood Hits	298	Shared Neighborhood Hits	184
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WIPI1_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.059261 (rank : 345)
Query Neighborhood Hits	368	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q5MNZ9, Q8IXM5, Q9NWF8	Gene names	WIPI1, WIPI49
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa) (Atg18 protein homolog).

WIPI1_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.067280 (rank : 341)
Query Neighborhood Hits	368	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R3E3, Q8BGE1, Q8R1A9, Q8R1C7	Gene names	Wipi1, D11Ertd498e
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa).

WIPI3_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.054287 (rank : 349)
Query Neighborhood Hits	368	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q5MNZ6, O95328, Q6IBN2	Gene names	WDR45L, WIPI3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein) (WIPI49-like protein).

WIPI3_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.054592 (rank : 348)
Query Neighborhood Hits	368	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CR39, Q3U924	Gene names	Wdr45l, Wipi3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein).

Hits sorted by NC score

SCAP_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	368	Target Neighborhood Hits	368	Shared Neighborhood Hits	368
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

FBXW7_MOUSE
NC score	0.721195 (rank : 2)	θ value	2.27762e-19 (rank : 3)
Query Neighborhood Hits	368	Target Neighborhood Hits	365	Shared Neighborhood Hits	198
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBXW7_HUMAN
NC score	0.718518 (rank : 3)	θ value	2.27762e-19 (rank : 2)
Query Neighborhood Hits	368	Target Neighborhood Hits	433	Shared Neighborhood Hits	198
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBW1A_HUMAN
NC score	0.703447 (rank : 4)	θ value	1.47974e-10 (rank : 8)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FBW1B_HUMAN
NC score	0.703157 (rank : 5)	θ value	1.9326e-10 (rank : 9)
Query Neighborhood Hits	368	Target Neighborhood Hits	327	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

WDR69_HUMAN
NC score	0.681809 (rank : 6)	θ value	3.29651e-10 (rank : 10)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	202
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

PLRG1_HUMAN
NC score	0.673015 (rank : 7)	θ value	3.41135e-07 (rank : 21)
Query Neighborhood Hits	368	Target Neighborhood Hits	318	Shared Neighborhood Hits	203
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

PLRG1_MOUSE
NC score	0.671801 (rank : 8)	θ value	9.92553e-07 (rank : 29)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	202
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

WDR5_HUMAN
NC score	0.669818 (rank : 9)	θ value	1.02475e-11 (rank : 6)
Query Neighborhood Hits	368	Target Neighborhood Hits	341	Shared Neighborhood Hits	205
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
NC score	0.669818 (rank : 10)	θ value	1.02475e-11 (rank : 7)
Query Neighborhood Hits	368	Target Neighborhood Hits	341	Shared Neighborhood Hits	205
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

PK1IP_MOUSE
NC score	0.664599 (rank : 11)	θ value	3.64472e-09 (rank : 12)
Query Neighborhood Hits	368	Target Neighborhood Hits	313	Shared Neighborhood Hits	198
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

PK1IP_HUMAN
NC score	0.664211 (rank : 12)	θ value	9.59137e-10 (rank : 11)
Query Neighborhood Hits	368	Target Neighborhood Hits	277	Shared Neighborhood Hits	192
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

LIS1_MOUSE
NC score	0.663620 (rank : 13)	θ value	0.00020696 (rank : 75)
Query Neighborhood Hits	368	Target Neighborhood Hits	336	Shared Neighborhood Hits	203
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_HUMAN
NC score	0.663610 (rank : 14)	θ value	0.00020696 (rank : 74)
Query Neighborhood Hits	368	Target Neighborhood Hits	333	Shared Neighborhood Hits	203
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

WDR71_HUMAN
NC score	0.663416 (rank : 15)	θ value	0.000786445 (rank : 88)
Query Neighborhood Hits	368	Target Neighborhood Hits	241	Shared Neighborhood Hits	183
SwissProt Accessions	Q9BRP4, Q4G165, Q53HS9, Q7Z500, Q8TBU6, Q9HAB6	Gene names	WDR71
Domain Architecture	No domain graphic available
Description	WD repeat protein 71 (Protein G-16).

WDR3_HUMAN
NC score	0.662734 (rank : 16)	θ value	2.61198e-07 (rank : 20)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

MORG1_HUMAN
NC score	0.657357 (rank : 17)	θ value	3.19293e-05 (rank : 55)
Query Neighborhood Hits	368	Target Neighborhood Hits	280	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BRX9, Q53FT6	Gene names	MORG1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

U3IP2_HUMAN
NC score	0.656698 (rank : 18)	θ value	2.21117e-06 (rank : 35)
Query Neighborhood Hits	368	Target Neighborhood Hits	307	Shared Neighborhood Hits	197
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

FBXW2_MOUSE
NC score	0.656448 (rank : 19)	θ value	1.87187e-05 (rank : 46)
Query Neighborhood Hits	368	Target Neighborhood Hits	249	Shared Neighborhood Hits	190
SwissProt Accessions	Q60584	Gene names	Fbxw2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

U3IP2_MOUSE
NC score	0.655925 (rank : 20)	θ value	3.77169e-06 (rank : 38)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	196
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

MORG1_MOUSE
NC score	0.654748 (rank : 21)	θ value	0.00020696 (rank : 76)
Query Neighborhood Hits	368	Target Neighborhood Hits	281	Shared Neighborhood Hits	199
SwissProt Accessions	Q9DAJ4, Q505C2, Q8VEB7, Q99JX9, Q9D235	Gene names	Morg1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

FBXW2_HUMAN
NC score	0.654629 (rank : 22)	θ value	2.44474e-05 (rank : 51)
Query Neighborhood Hits	368	Target Neighborhood Hits	260	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

TBL3_HUMAN
NC score	0.653213 (rank : 23)	θ value	0.00134147 (rank : 93)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	195
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

GBLP_HUMAN
NC score	0.648126 (rank : 24)	θ value	0.000121331 (rank : 70)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	204
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
NC score	0.648126 (rank : 25)	θ value	0.000121331 (rank : 71)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	204
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

APAF_HUMAN
NC score	0.647120 (rank : 26)	θ value	1.99992e-07 (rank : 16)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	202
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

KTNB1_HUMAN
NC score	0.645586 (rank : 27)	θ value	7.59969e-07 (rank : 25)
Query Neighborhood Hits	368	Target Neighborhood Hits	349	Shared Neighborhood Hits	205
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
NC score	0.645490 (rank : 28)	θ value	7.59969e-07 (rank : 26)
Query Neighborhood Hits	368	Target Neighborhood Hits	356	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

TAF5L_HUMAN
NC score	0.644922 (rank : 29)	θ value	2.61198e-07 (rank : 19)
Query Neighborhood Hits	368	Target Neighborhood Hits	330	Shared Neighborhood Hits	202
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

TAF5_HUMAN
NC score	0.644738 (rank : 30)	θ value	2.21117e-06 (rank : 33)
Query Neighborhood Hits	368	Target Neighborhood Hits	352	Shared Neighborhood Hits	203
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5_MOUSE
NC score	0.644559 (rank : 31)	θ value	2.21117e-06 (rank : 34)
Query Neighborhood Hits	368	Target Neighborhood Hits	366	Shared Neighborhood Hits	205
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5L_MOUSE
NC score	0.644266 (rank : 32)	θ value	7.59969e-07 (rank : 27)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	203
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

NLE1_HUMAN
NC score	0.640901 (rank : 33)	θ value	2.44474e-05 (rank : 53)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	205
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

PWP2_HUMAN
NC score	0.640224 (rank : 34)	θ value	1.53129e-07 (rank : 15)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	197
SwissProt Accessions	Q15269, Q96A77	Gene names	PWP2H, PWP2
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

SPG16_HUMAN
NC score	0.640061 (rank : 35)	θ value	5.44631e-05 (rank : 63)
Query Neighborhood Hits	368	Target Neighborhood Hits	361	Shared Neighborhood Hits	200
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

WD51A_MOUSE
NC score	0.639989 (rank : 36)	θ value	1.09739e-05 (rank : 44)
Query Neighborhood Hits	368	Target Neighborhood Hits	342	Shared Neighborhood Hits	204
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WDR12_MOUSE
NC score	0.639672 (rank : 37)	θ value	2.21117e-06 (rank : 36)
Query Neighborhood Hits	368	Target Neighborhood Hits	301	Shared Neighborhood Hits	193
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WDR12_HUMAN
NC score	0.638412 (rank : 38)	θ value	1.29631e-06 (rank : 30)
Query Neighborhood Hits	368	Target Neighborhood Hits	300	Shared Neighborhood Hits	192
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WD51A_HUMAN
NC score	0.637472 (rank : 39)	θ value	0.000121331 (rank : 72)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	202
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WDR31_MOUSE
NC score	0.637315 (rank : 40)	θ value	3.19293e-05 (rank : 58)
Query Neighborhood Hits	368	Target Neighborhood Hits	287	Shared Neighborhood Hits	193
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

AAMP_HUMAN
NC score	0.637207 (rank : 41)	θ value	0.0252991 (rank : 132)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

NLE1_MOUSE
NC score	0.636967 (rank : 42)	θ value	0.00020696 (rank : 77)
Query Neighborhood Hits	368	Target Neighborhood Hits	332	Shared Neighborhood Hits	204
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

PRP19_HUMAN
NC score	0.636909 (rank : 43)	θ value	3.19293e-05 (rank : 56)
Query Neighborhood Hits	368	Target Neighborhood Hits	333	Shared Neighborhood Hits	205
SwissProt Accessions	Q9UMS4	Gene names	PRPF19, NMP200, PRP19
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (hPso4).

WDR57_HUMAN
NC score	0.636330 (rank : 44)	θ value	7.1131e-05 (rank : 65)
Query Neighborhood Hits	368	Target Neighborhood Hits	322	Shared Neighborhood Hits	205
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

APAF_MOUSE
NC score	0.636207 (rank : 45)	θ value	1.09739e-05 (rank : 43)
Query Neighborhood Hits	368	Target Neighborhood Hits	343	Shared Neighborhood Hits	205
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

WDR57_MOUSE
NC score	0.636091 (rank : 46)	θ value	9.29e-05 (rank : 67)
Query Neighborhood Hits	368	Target Neighborhood Hits	323	Shared Neighborhood Hits	205
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

PRP19_MOUSE
NC score	0.635961 (rank : 47)	θ value	5.44631e-05 (rank : 62)
Query Neighborhood Hits	368	Target Neighborhood Hits	335	Shared Neighborhood Hits	205
SwissProt Accessions	Q99KP6, Q3TP64, Q8BKZ5, Q8BVQ4	Gene names	Prpf19, Prp19, Snev
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (Nuclear matrix protein SNEV).

PWP2_MOUSE
NC score	0.635721 (rank : 48)	θ value	4.45536e-07 (rank : 23)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	195
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

SPG16_MOUSE
NC score	0.633596 (rank : 49)	θ value	0.000270298 (rank : 79)
Query Neighborhood Hits	368	Target Neighborhood Hits	377	Shared Neighborhood Hits	196
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

PRP4_MOUSE
NC score	0.632629 (rank : 50)	θ value	0.0431538 (rank : 144)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	202
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

WD51B_MOUSE
NC score	0.632474 (rank : 51)	θ value	9.29e-05 (rank : 66)
Query Neighborhood Hits	368	Target Neighborhood Hits	321	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

COPA_HUMAN
NC score	0.632370 (rank : 52)	θ value	0.00102713 (rank : 89)
Query Neighborhood Hits	368	Target Neighborhood Hits	297	Shared Neighborhood Hits	196
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

PRP4_HUMAN
NC score	0.632253 (rank : 53)	θ value	0.0431538 (rank : 143)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	202
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

WD51B_HUMAN
NC score	0.632030 (rank : 54)	θ value	0.000158464 (rank : 73)
Query Neighborhood Hits	368	Target Neighborhood Hits	335	Shared Neighborhood Hits	205
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WDR37_MOUSE
NC score	0.631587 (rank : 55)	θ value	0.00175202 (rank : 94)
Query Neighborhood Hits	368	Target Neighborhood Hits	298	Shared Neighborhood Hits	192
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

UTP15_MOUSE
NC score	0.630025 (rank : 56)	θ value	1.87187e-05 (rank : 49)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	198
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

WDR37_HUMAN
NC score	0.627842 (rank : 57)	θ value	0.00390308 (rank : 104)
Query Neighborhood Hits	368	Target Neighborhood Hits	303	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

WDR61_HUMAN
NC score	0.627817 (rank : 58)	θ value	0.00298849 (rank : 101)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	203
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

GBB1_HUMAN
NC score	0.627805 (rank : 59)	θ value	1.87187e-05 (rank : 47)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	P62873, P04697, P04901	Gene names	GNB1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB1_MOUSE
NC score	0.627805 (rank : 60)	θ value	1.87187e-05 (rank : 48)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	P62874, P04697, P04901	Gene names	Gnb1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

WDR61_MOUSE
NC score	0.627028 (rank : 61)	θ value	0.00509761 (rank : 109)
Query Neighborhood Hits	368	Target Neighborhood Hits	331	Shared Neighborhood Hits	203
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

WDR31_HUMAN
NC score	0.625385 (rank : 62)	θ value	0.00298849 (rank : 100)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	192
SwissProt Accessions	Q8NA23, Q96EG8	Gene names	WDR31
Domain Architecture
Description	WD repeat protein 31.

WDR17_HUMAN
NC score	0.625196 (rank : 63)	θ value	2.21117e-06 (rank : 37)
Query Neighborhood Hits	368	Target Neighborhood Hits	335	Shared Neighborhood Hits	197
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

UTP15_HUMAN
NC score	0.625076 (rank : 64)	θ value	4.1701e-05 (rank : 59)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	196
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

PLAP_HUMAN
NC score	0.624084 (rank : 65)	θ value	0.00298849 (rank : 99)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

PLAP_MOUSE
NC score	0.623031 (rank : 66)	θ value	0.0148317 (rank : 123)
Query Neighborhood Hits	368	Target Neighborhood Hits	261	Shared Neighborhood Hits	188
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

GBB3_HUMAN
NC score	0.622044 (rank : 67)	θ value	0.00102713 (rank : 90)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	197
SwissProt Accessions	P16520, Q9BQC0	Gene names	GNB3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

GBB3_MOUSE
NC score	0.621487 (rank : 68)	θ value	0.000602161 (rank : 83)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	197
SwissProt Accessions	Q61011	Gene names	Gnb3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

GBB4_MOUSE
NC score	0.621183 (rank : 69)	θ value	0.000121331 (rank : 69)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	196
SwissProt Accessions	P29387, Q3TJJ1, Q8R475, Q9JHX8	Gene names	Gnb4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

GBB5_MOUSE
NC score	0.620032 (rank : 70)	θ value	0.00665767 (rank : 110)
Query Neighborhood Hits	368	Target Neighborhood Hits	298	Shared Neighborhood Hits	200
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

TBL1Y_HUMAN
NC score	0.619838 (rank : 71)	θ value	4.92598e-06 (rank : 39)
Query Neighborhood Hits	368	Target Neighborhood Hits	331	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

GBB5_HUMAN
NC score	0.619663 (rank : 72)	θ value	0.00509761 (rank : 107)
Query Neighborhood Hits	368	Target Neighborhood Hits	299	Shared Neighborhood Hits	200
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GBB2_HUMAN
NC score	0.619426 (rank : 73)	θ value	5.44631e-05 (rank : 60)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	P62879, P11016, P54312	Gene names	GNB2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

GBB2_MOUSE
NC score	0.619426 (rank : 74)	θ value	5.44631e-05 (rank : 61)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	198
SwissProt Accessions	P62880, P11016, P54312	Gene names	Gnb2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

COPB2_HUMAN
NC score	0.619213 (rank : 75)	θ value	0.00869519 (rank : 112)
Query Neighborhood Hits	368	Target Neighborhood Hits	315	Shared Neighborhood Hits	200
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

GBB4_HUMAN
NC score	0.619111 (rank : 76)	θ value	0.00035302 (rank : 81)
Query Neighborhood Hits	368	Target Neighborhood Hits	288	Shared Neighborhood Hits	195
SwissProt Accessions	Q9HAV0	Gene names	GNB4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

TBLX_MOUSE
NC score	0.618976 (rank : 77)	θ value	4.92598e-06 (rank : 40)
Query Neighborhood Hits	368	Target Neighborhood Hits	335	Shared Neighborhood Hits	199
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

COPB2_MOUSE
NC score	0.618975 (rank : 78)	θ value	0.00869519 (rank : 113)
Query Neighborhood Hits	368	Target Neighborhood Hits	315	Shared Neighborhood Hits	200
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

TBL1R_HUMAN
NC score	0.618552 (rank : 79)	θ value	8.40245e-06 (rank : 41)
Query Neighborhood Hits	368	Target Neighborhood Hits	327	Shared Neighborhood Hits	197
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
NC score	0.618120 (rank : 80)	θ value	8.40245e-06 (rank : 42)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1X_HUMAN
NC score	0.615827 (rank : 81)	θ value	5.44631e-05 (rank : 64)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	197
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

WDR48_HUMAN
NC score	0.615448 (rank : 82)	θ value	0.279714 (rank : 178)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	198
SwissProt Accessions	Q8TAF3, Q63HJ2, Q658Y1, Q8N3Z1, Q9NSK8, Q9P279	Gene names	WDR48, KIAA1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48 (WD repeat endosomal protein) (p80).

WDR48_MOUSE
NC score	0.613172 (rank : 83)	θ value	0.279714 (rank : 179)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	198
SwissProt Accessions	Q8BH57, Q80TD4, Q80XI0, Q8BRM0, Q8CBK0, Q922Z9, Q9CRR1, Q9CSL0	Gene names	Wdr48, Kiaa1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48.

SMU1_HUMAN
NC score	0.610572 (rank : 84)	θ value	0.0113563 (rank : 119)
Query Neighborhood Hits	368	Target Neighborhood Hits	311	Shared Neighborhood Hits	200
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
NC score	0.610572 (rank : 85)	θ value	0.0113563 (rank : 120)
Query Neighborhood Hits	368	Target Neighborhood Hits	311	Shared Neighborhood Hits	200
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

TEP1_HUMAN
NC score	0.608957 (rank : 86)	θ value	3.41135e-07 (rank : 22)
Query Neighborhood Hits	368	Target Neighborhood Hits	371	Shared Neighborhood Hits	203
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

WSB2_HUMAN
NC score	0.606893 (rank : 87)	θ value	0.0148317 (rank : 127)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	199
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

PRP17_MOUSE
NC score	0.606588 (rank : 88)	θ value	0.0252991 (rank : 134)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	193
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

WDR47_MOUSE
NC score	0.606396 (rank : 89)	θ value	0.000786445 (rank : 87)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	181
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

PRP17_HUMAN
NC score	0.606017 (rank : 90)	θ value	0.0252991 (rank : 133)
Query Neighborhood Hits	368	Target Neighborhood Hits	297	Shared Neighborhood Hits	194
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

WDR47_HUMAN
NC score	0.605728 (rank : 91)	θ value	0.000786445 (rank : 86)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	179
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WSB2_MOUSE
NC score	0.605251 (rank : 92)	θ value	0.0193708 (rank : 131)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	199
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

CSTF1_HUMAN
NC score	0.603942 (rank : 93)	θ value	0.00228821 (rank : 95)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	188
SwissProt Accessions	Q05048	Gene names	CSTF1
Domain Architecture
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

TEP1_MOUSE
NC score	0.599683 (rank : 94)	θ value	3.19293e-05 (rank : 57)
Query Neighborhood Hits	368	Target Neighborhood Hits	344	Shared Neighborhood Hits	202
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

CSTF1_MOUSE
NC score	0.598870 (rank : 95)	θ value	0.00298849 (rank : 98)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	187
SwissProt Accessions	Q99LC2, Q3UMB8, Q8BJW1, Q9CSU8	Gene names	Cstf1
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

TRAF7_MOUSE
NC score	0.596715 (rank : 96)	θ value	0.00102713 (rank : 92)
Query Neighborhood Hits	368	Target Neighborhood Hits	470	Shared Neighborhood Hits	192
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

WSB1_HUMAN
NC score	0.596672 (rank : 97)	θ value	0.0148317 (rank : 126)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

TRAF7_HUMAN
NC score	0.594792 (rank : 98)	θ value	0.00102713 (rank : 91)
Query Neighborhood Hits	368	Target Neighborhood Hits	482	Shared Neighborhood Hits	192
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

STRAP_HUMAN
NC score	0.589091 (rank : 99)	θ value	1.06291 (rank : 209)
Query Neighborhood Hits	368	Target Neighborhood Hits	272	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y3F4, Q9UQC8	Gene names	STRAP, MAWD, UNRIP
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein) (WD-40 repeat protein PT-WD) (MAP activator with WD repeats).

STRAP_MOUSE
NC score	0.589053 (rank : 100)	θ value	1.06291 (rank : 210)
Query Neighborhood Hits	368	Target Neighborhood Hits	279	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Z1Z2	Gene names	Strap, Unrip
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein).

WSB1_MOUSE
NC score	0.585550 (rank : 101)	θ value	0.21417 (rank : 170)
Query Neighborhood Hits	368	Target Neighborhood Hits	313	Shared Neighborhood Hits	198
SwissProt Accessions	O54927	Gene names	Wsb1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1).

BRWD1_HUMAN
NC score	0.584218 (rank : 102)	θ value	2.44474e-05 (rank : 50)
Query Neighborhood Hits	368	Target Neighborhood Hits	448	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

FBXW9_HUMAN
NC score	0.582430 (rank : 103)	θ value	3.19293e-05 (rank : 54)
Query Neighborhood Hits	368	Target Neighborhood Hits	184	Shared Neighborhood Hits	147
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

BRWD1_MOUSE
NC score	0.580591 (rank : 104)	θ value	1.87187e-05 (rank : 45)
Query Neighborhood Hits	368	Target Neighborhood Hits	478	Shared Neighborhood Hits	209
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

WDR1_HUMAN
NC score	0.575521 (rank : 105)	θ value	0.0563607 (rank : 150)
Query Neighborhood Hits	368	Target Neighborhood Hits	292	Shared Neighborhood Hits	192
SwissProt Accessions	O75083, O75313, Q8N6E5, Q9UG05, Q9UG78, Q9UQE0	Gene names	WDR1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1).

A16L1_HUMAN
NC score	0.572371 (rank : 106)	θ value	0.00869519 (rank : 111)
Query Neighborhood Hits	368	Target Neighborhood Hits	664	Shared Neighborhood Hits	197
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

PEX7_MOUSE
NC score	0.570902 (rank : 107)	θ value	1.81305 (rank : 236)
Query Neighborhood Hits	368	Target Neighborhood Hits	279	Shared Neighborhood Hits	188
SwissProt Accessions	P97865	Gene names	Pex7
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

CDC20_HUMAN
NC score	0.567762 (rank : 108)	θ value	0.0736092 (rank : 152)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	194
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

WDR1_MOUSE
NC score	0.566987 (rank : 109)	θ value	0.125558 (rank : 161)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	191
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

WDR18_HUMAN
NC score	0.566213 (rank : 110)	θ value	0.125558 (rank : 160)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	183
SwissProt Accessions	Q9BV38, O60390, Q9BWR2	Gene names	WDR18
Domain Architecture
Description	WD repeat protein 18.

ERCC8_MOUSE
NC score	0.565876 (rank : 111)	θ value	0.0330416 (rank : 139)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	185
SwissProt Accessions	Q8CFD5, Q3U066, Q8VDC4, Q9CWK7	Gene names	Ercc8, Ckn1, Csa
Domain Architecture	No domain graphic available
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog).

WDR39_HUMAN
NC score	0.565661 (rank : 112)	θ value	1.38821 (rank : 232)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	187
SwissProt Accessions	O76071	Gene names	WDR39, CIAO1
Domain Architecture
Description	WD repeat protein 39 (Ciao 1 protein).

PEX7_HUMAN
NC score	0.565498 (rank : 113)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	368	Target Neighborhood Hits	275	Shared Neighborhood Hits	187
SwissProt Accessions	O00628	Gene names	PEX7, PTS2R
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

GNB1L_MOUSE
NC score	0.564207 (rank : 114)	θ value	0.0961366 (rank : 157)
Query Neighborhood Hits	368	Target Neighborhood Hits	231	Shared Neighborhood Hits	169
SwissProt Accessions	Q9EQ15, Q8R1F3, Q9CWP2, Q9D3Y1	Gene names	Gnb1l, Estm55, Wdr14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF).

ERCC8_HUMAN
NC score	0.562660 (rank : 115)	θ value	0.0961366 (rank : 156)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	186
SwissProt Accessions	Q13216, Q6FHX5, Q96GB9	Gene names	ERCC8, CKN1, CSA
Domain Architecture
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA).

FZR_MOUSE
NC score	0.561532 (rank : 116)	θ value	0.279714 (rank : 176)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	193
SwissProt Accessions	Q9R1K5	Gene names	Fzr1, Fyr, Fzr
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog).

FZR_HUMAN
NC score	0.560995 (rank : 117)	θ value	0.279714 (rank : 175)
Query Neighborhood Hits	368	Target Neighborhood Hits	279	Shared Neighborhood Hits	191
SwissProt Accessions	Q9UM11, O75869, Q86U66, Q96NW8, Q9UI96, Q9ULH8, Q9UM10, Q9UNQ1, Q9Y2T8	Gene names	FZR1, CDH1, FYR, FZR, KIAA1242
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1) (CDC20-like protein 1).

WDR16_HUMAN
NC score	0.560624 (rank : 118)	θ value	0.365318 (rank : 187)
Query Neighborhood Hits	368	Target Neighborhood Hits	275	Shared Neighborhood Hits	191
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

A16L1_MOUSE
NC score	0.558365 (rank : 119)	θ value	0.0113563 (rank : 116)
Query Neighborhood Hits	368	Target Neighborhood Hits	776	Shared Neighborhood Hits	195
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

WDR16_MOUSE
NC score	0.557706 (rank : 120)	θ value	1.38821 (rank : 231)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	189
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

IF32_MOUSE
NC score	0.553520 (rank : 121)	θ value	0.365318 (rank : 185)
Query Neighborhood Hits	368	Target Neighborhood Hits	239	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QZD9	Gene names	Eif3s2, Trip1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

IF32_HUMAN
NC score	0.552464 (rank : 122)	θ value	0.365318 (rank : 184)
Query Neighborhood Hits	368	Target Neighborhood Hits	239	Shared Neighborhood Hits	176
SwissProt Accessions	Q13347	Gene names	EIF3S2, TRIP1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

CDC20_MOUSE
NC score	0.550638 (rank : 123)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	191
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

WDR18_MOUSE
NC score	0.550164 (rank : 124)	θ value	2.36792 (rank : 258)
Query Neighborhood Hits	368	Target Neighborhood Hits	239	Shared Neighborhood Hits	176
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

WDR36_HUMAN
NC score	0.546316 (rank : 125)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	368	Target Neighborhood Hits	274	Shared Neighborhood Hits	188
SwissProt Accessions	Q8NI36, Q8N1Q2	Gene names	WDR36
Domain Architecture
Description	WD repeat protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP).

GNB1L_HUMAN
NC score	0.543039 (rank : 126)	θ value	0.0113563 (rank : 118)
Query Neighborhood Hits	368	Target Neighborhood Hits	221	Shared Neighborhood Hits	160
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

STRN3_HUMAN
NC score	0.542265 (rank : 127)	θ value	0.00869519 (rank : 115)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	193
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

STRN3_MOUSE
NC score	0.541009 (rank : 128)	θ value	0.00390308 (rank : 102)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	189
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

STRN4_MOUSE
NC score	0.538181 (rank : 129)	θ value	0.0563607 (rank : 148)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	197
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

PWP1_MOUSE
NC score	0.536803 (rank : 130)	θ value	0.0252991 (rank : 135)
Query Neighborhood Hits	368	Target Neighborhood Hits	278	Shared Neighborhood Hits	182
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

GRWD1_HUMAN
NC score	0.534785 (rank : 131)	θ value	0.00509761 (rank : 108)
Query Neighborhood Hits	368	Target Neighborhood Hits	297	Shared Neighborhood Hits	191
SwissProt Accessions	Q9BQ67	Gene names	GRWD1, GRWD, WDR28
Domain Architecture
Description	Glutamate-rich WD repeat-containing protein 1.

STRN4_HUMAN
NC score	0.534316 (rank : 132)	θ value	0.163984 (rank : 166)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	195
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

STRN_MOUSE
NC score	0.533476 (rank : 133)	θ value	0.00390308 (rank : 103)
Query Neighborhood Hits	368	Target Neighborhood Hits	326	Shared Neighborhood Hits	188
SwissProt Accessions	O55106	Gene names	Strn
Domain Architecture
Description	Striatin.

GRWD1_MOUSE
NC score	0.532712 (rank : 134)	θ value	0.00228821 (rank : 96)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	191
SwissProt Accessions	Q810D6, Q922H3	Gene names	Grwd1, A301
Domain Architecture	No domain graphic available
Description	Glutamate-rich WD repeat-containing protein 1 (Protein A301).

THOC3_HUMAN
NC score	0.532148 (rank : 135)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	191
SwissProt Accessions	Q96J01	Gene names	THOC3
Domain Architecture
Description	THO complex subunit 3 (Tho3) (TEX1 homolog).

FAN_HUMAN
NC score	0.532036 (rank : 136)	θ value	0.000786445 (rank : 84)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	197
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

THOC3_MOUSE
NC score	0.530946 (rank : 137)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	191
SwissProt Accessions	Q8VE80, Q9CWI8	Gene names	Thoc3
Domain Architecture
Description	THO complex subunit 3 (Tho3).

FBXW4_MOUSE
NC score	0.530259 (rank : 138)	θ value	2.44474e-05 (rank : 52)
Query Neighborhood Hits	368	Target Neighborhood Hits	205	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

WDR53_HUMAN
NC score	0.527731 (rank : 139)	θ value	0.0193708 (rank : 130)
Query Neighborhood Hits	368	Target Neighborhood Hits	251	Shared Neighborhood Hits	175
SwissProt Accessions	Q7Z5U6	Gene names	WDR53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

STRN_HUMAN
NC score	0.526950 (rank : 140)	θ value	0.0252991 (rank : 136)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	190
SwissProt Accessions	O43815, Q9NP38	Gene names	STRN
Domain Architecture
Description	Striatin.

WDR23_MOUSE
NC score	0.526477 (rank : 141)	θ value	1.06291 (rank : 212)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	181
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

ZF106_HUMAN
NC score	0.523929 (rank : 142)	θ value	0.00020696 (rank : 78)
Query Neighborhood Hits	368	Target Neighborhood Hits	470	Shared Neighborhood Hits	159
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

CAF1B_MOUSE
NC score	0.523767 (rank : 143)	θ value	0.365318 (rank : 181)
Query Neighborhood Hits	368	Target Neighborhood Hits	385	Shared Neighborhood Hits	200
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

WDR53_MOUSE
NC score	0.523529 (rank : 144)	θ value	0.0148317 (rank : 125)
Query Neighborhood Hits	368	Target Neighborhood Hits	254	Shared Neighborhood Hits	175
SwissProt Accessions	Q9DB94	Gene names	Wdr53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

WDR33_HUMAN
NC score	0.522644 (rank : 145)	θ value	0.163984 (rank : 167)
Query Neighborhood Hits	368	Target Neighborhood Hits	638	Shared Neighborhood Hits	229
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ZF106_MOUSE
NC score	0.521988 (rank : 146)	θ value	0.000270298 (rank : 80)
Query Neighborhood Hits	368	Target Neighborhood Hits	472	Shared Neighborhood Hits	166
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

CAF1B_HUMAN
NC score	0.520932 (rank : 147)	θ value	0.813845 (rank : 198)
Query Neighborhood Hits	368	Target Neighborhood Hits	345	Shared Neighborhood Hits	193
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

WDR23_HUMAN
NC score	0.520748 (rank : 148)	θ value	1.06291 (rank : 211)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	180
SwissProt Accessions	Q8TEB1, Q86U00, Q86U39, Q8NDN2, Q9H2J0, Q9H3A3, Q9H5C9	Gene names	WDR23
Domain Architecture
Description	WD repeat protein 23.

WDR49_HUMAN
NC score	0.519378 (rank : 149)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	368	Target Neighborhood Hits	214	Shared Neighborhood Hits	162
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

FAN_MOUSE
NC score	0.517197 (rank : 150)	θ value	0.00509761 (rank : 105)
Query Neighborhood Hits	368	Target Neighborhood Hits	292	Shared Neighborhood Hits	193
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

WDR26_HUMAN
NC score	0.515363 (rank : 151)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	191
SwissProt Accessions	Q9H7D7, Q86UY4	Gene names	WDR26
Domain Architecture
Description	WD repeat protein 26.

WDR26_MOUSE
NC score	0.513912 (rank : 152)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	368	Target Neighborhood Hits	295	Shared Neighborhood Hits	191
SwissProt Accessions	Q8C6G8, Q8C4F3, Q8VDZ6	Gene names	Wdr26
Domain Architecture
Description	WD repeat protein 26.

FBXW4_HUMAN
NC score	0.512611 (rank : 153)	θ value	0.000121331 (rank : 68)
Query Neighborhood Hits	368	Target Neighborhood Hits	209	Shared Neighborhood Hits	145
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

PWP1_HUMAN
NC score	0.511270 (rank : 154)	θ value	2.36792 (rank : 254)
Query Neighborhood Hits	368	Target Neighborhood Hits	261	Shared Neighborhood Hits	177
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

WDR65_HUMAN
NC score	0.507305 (rank : 155)	θ value	0.125558 (rank : 162)
Query Neighborhood Hits	368	Target Neighborhood Hits	238	Shared Neighborhood Hits	170
SwissProt Accessions	Q96MR6, Q5TAI0	Gene names	WDR65
Domain Architecture	No domain graphic available
Description	WD repeat protein 65.

MEP50_MOUSE
NC score	0.504859 (rank : 156)	θ value	0.163984 (rank : 165)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	182
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

WDR55_HUMAN
NC score	0.499033 (rank : 157)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	368	Target Neighborhood Hits	231	Shared Neighborhood Hits	168
SwissProt Accessions	Q9H6Y2	Gene names	WDR55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

THOC6_HUMAN
NC score	0.498013 (rank : 158)	θ value	0.0113563 (rank : 121)
Query Neighborhood Hits	368	Target Neighborhood Hits	223	Shared Neighborhood Hits	172
SwissProt Accessions	Q86W42, Q8NBR1, Q9BTV9	Gene names	THOC6, WDR58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

WDR24_MOUSE
NC score	0.490527 (rank : 159)	θ value	0.00228821 (rank : 97)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

MEP50_HUMAN
NC score	0.489476 (rank : 160)	θ value	1.38821 (rank : 221)
Query Neighborhood Hits	368	Target Neighborhood Hits	268	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BQA1, Q96GK4, Q9BWY3	Gene names	WDR77, MEP50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

WDR55_MOUSE
NC score	0.488171 (rank : 161)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	368	Target Neighborhood Hits	236	Shared Neighborhood Hits	168
SwissProt Accessions	Q9CX97	Gene names	Wdr55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

RBBP4_HUMAN
NC score	0.481777 (rank : 162)	θ value	1.81305 (rank : 238)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	191
SwissProt Accessions	Q09028, P31149, Q53H02, Q96BV9	Gene names	RBBP4, RBAP48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

RBBP4_MOUSE
NC score	0.481753 (rank : 163)	θ value	1.81305 (rank : 239)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	189
SwissProt Accessions	Q60972	Gene names	Rbbp4, Rbap48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

WDR41_MOUSE
NC score	0.479988 (rank : 164)	θ value	0.0252991 (rank : 137)
Query Neighborhood Hits	368	Target Neighborhood Hits	209	Shared Neighborhood Hits	155
SwissProt Accessions	Q3UDP0, Q8C4F1, Q8C8K5	Gene names	Wdr41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

RBBP7_MOUSE
NC score	0.479379 (rank : 165)	θ value	1.38821 (rank : 223)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	191
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_HUMAN
NC score	0.479298 (rank : 166)	θ value	1.38821 (rank : 222)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	191
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

WDR43_HUMAN
NC score	0.477753 (rank : 167)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	144
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

NEDD1_MOUSE
NC score	0.474105 (rank : 168)	θ value	2.36792 (rank : 252)
Query Neighborhood Hits	368	Target Neighborhood Hits	281	Shared Neighborhood Hits	162
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

NEDD1_HUMAN
NC score	0.471894 (rank : 169)	θ value	2.36792 (rank : 251)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	171
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

RBBP5_HUMAN
NC score	0.470019 (rank : 170)	θ value	0.0148317 (rank : 124)
Query Neighborhood Hits	368	Target Neighborhood Hits	372	Shared Neighborhood Hits	161
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

THOC6_MOUSE
NC score	0.465469 (rank : 171)	θ value	0.0563607 (rank : 149)
Query Neighborhood Hits	368	Target Neighborhood Hits	199	Shared Neighborhood Hits	157
SwissProt Accessions	Q5U4D9	Gene names	Thoc6, Wdr58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

WDFY1_HUMAN
NC score	0.463397 (rank : 172)	θ value	0.0113563 (rank : 122)
Query Neighborhood Hits	368	Target Neighborhood Hits	305	Shared Neighborhood Hits	182
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

TBL2_HUMAN
NC score	0.460174 (rank : 173)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y4P3, Q9UQE2	Gene names	TBL2, WBSCR13
Domain Architecture
Description	Transducin beta-like 2 protein (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosome region 13 protein).

WDR41_HUMAN
NC score	0.452353 (rank : 174)	θ value	0.47712 (rank : 190)
Query Neighborhood Hits	368	Target Neighborhood Hits	208	Shared Neighborhood Hits	165
SwissProt Accessions	Q9HAD4, Q7Z792, Q8IWG3, Q8IXA9, Q8NDA7, Q9NV62	Gene names	WDR41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

WDR79_MOUSE
NC score	0.451292 (rank : 175)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	368	Target Neighborhood Hits	216	Shared Neighborhood Hits	149
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

HIRA_MOUSE
NC score	0.450466 (rank : 176)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	368	Target Neighborhood Hits	274	Shared Neighborhood Hits	175
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

WDHD1_MOUSE
NC score	0.450408 (rank : 177)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	368	Target Neighborhood Hits	414	Shared Neighborhood Hits	183
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

HIRA_HUMAN
NC score	0.448806 (rank : 178)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	368	Target Neighborhood Hits	279	Shared Neighborhood Hits	173
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

RFWD2_HUMAN
NC score	0.447922 (rank : 179)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	368	Target Neighborhood Hits	518	Shared Neighborhood Hits	178
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
NC score	0.447011 (rank : 180)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	368	Target Neighborhood Hits	535	Shared Neighborhood Hits	178
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

BOP1_MOUSE
NC score	0.446028 (rank : 181)	θ value	0.365318 (rank : 180)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	177
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

WDHD1_HUMAN
NC score	0.444320 (rank : 182)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	368	Target Neighborhood Hits	342	Shared Neighborhood Hits	171
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

WDR6_HUMAN
NC score	0.443662 (rank : 183)	θ value	0.0563607 (rank : 151)
Query Neighborhood Hits	368	Target Neighborhood Hits	193	Shared Neighborhood Hits	141
SwissProt Accessions	Q9NNW5, Q9UF63	Gene names	WDR6
Domain Architecture
Description	WD repeat protein 6.

RAE1L_MOUSE
NC score	0.440642 (rank : 184)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

TBL2_MOUSE
NC score	0.438778 (rank : 185)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	368	Target Neighborhood Hits	221	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R099	Gene names	Tbl2
Domain Architecture
Description	Transducin beta-like 2 protein.

RAE1L_HUMAN
NC score	0.438607 (rank : 186)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	368	Target Neighborhood Hits	222	Shared Neighborhood Hits	166
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

IF122_HUMAN
NC score	0.434203 (rank : 187)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	368	Target Neighborhood Hits	244	Shared Neighborhood Hits	166
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

BUB3_HUMAN
NC score	0.431799 (rank : 188)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	155
SwissProt Accessions	O43684, O43685	Gene names	BUB3
Domain Architecture
Description	Mitotic checkpoint protein BUB3.

GEMI5_MOUSE
NC score	0.423503 (rank : 189)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	368	Target Neighborhood Hits	424	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

BUB3_MOUSE
NC score	0.422493 (rank : 190)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	368	Target Neighborhood Hits	199	Shared Neighborhood Hits	155
SwissProt Accessions	Q9WVA3, P97397	Gene names	Bub3
Domain Architecture
Description	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5).

WDFY2_HUMAN
NC score	0.420523 (rank : 191)	θ value	6.88961 (rank : 326)
Query Neighborhood Hits	368	Target Neighborhood Hits	332	Shared Neighborhood Hits	185
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDR22_MOUSE
NC score	0.418655 (rank : 192)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	368	Target Neighborhood Hits	302	Shared Neighborhood Hits	167
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

WDR7_MOUSE
NC score	0.417991 (rank : 193)	θ value	0.0431538 (rank : 145)
Query Neighborhood Hits	368	Target Neighborhood Hits	226	Shared Neighborhood Hits	159
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

WDR22_HUMAN
NC score	0.416540 (rank : 194)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	368	Target Neighborhood Hits	328	Shared Neighborhood Hits	174
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

WDFY2_MOUSE
NC score	0.415736 (rank : 195)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	185
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

GEMI5_HUMAN
NC score	0.415416 (rank : 196)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	368	Target Neighborhood Hits	362	Shared Neighborhood Hits	191
SwissProt Accessions	Q8TEQ6, Q8WWV4, Q969W4, Q9H9K3, Q9UFI5	Gene names	GEMIN5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

WDR7_HUMAN
NC score	0.414380 (rank : 197)	θ value	0.0252991 (rank : 138)
Query Neighborhood Hits	368	Target Neighborhood Hits	244	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

WDR79_HUMAN
NC score	0.411938 (rank : 198)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

BOP1_HUMAN
NC score	0.410115 (rank : 199)	θ value	4.03905 (rank : 274)
Query Neighborhood Hits	368	Target Neighborhood Hits	257	Shared Neighborhood Hits	167
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

AHI1_MOUSE
NC score	0.409685 (rank : 200)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	368	Target Neighborhood Hits	496	Shared Neighborhood Hits	177
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

CORO7_MOUSE
NC score	0.407984 (rank : 201)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	191
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

EMAL2_HUMAN
NC score	0.406280 (rank : 202)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	368	Target Neighborhood Hits	217	Shared Neighborhood Hits	155
SwissProt Accessions	O95834, Q9UG50	Gene names	EML2, EMAP2, EMAPL2
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2).

WDTC1_HUMAN
NC score	0.405806 (rank : 203)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	368	Target Neighborhood Hits	299	Shared Neighborhood Hits	183
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDTC1_MOUSE
NC score	0.405210 (rank : 204)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	368	Target Neighborhood Hits	298	Shared Neighborhood Hits	184
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDR75_HUMAN
NC score	0.401901 (rank : 205)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	368	Target Neighborhood Hits	193	Shared Neighborhood Hits	134
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

NUP43_MOUSE
NC score	0.401696 (rank : 206)	θ value	0.000786445 (rank : 85)
Query Neighborhood Hits	368	Target Neighborhood Hits	193	Shared Neighborhood Hits	142
SwissProt Accessions	P59235	Gene names	Nup43
Domain Architecture
Description	Nucleoporin Nup43.

STTP1_MOUSE
NC score	0.396969 (rank : 207)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	172
SwissProt Accessions	Q91WG4, Q3TIH5, Q3TIT0, Q8CBW6, Q9ESY7	Gene names	Statip1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1).

FBXW8_HUMAN
NC score	0.394772 (rank : 208)	θ value	0.000461057 (rank : 82)
Query Neighborhood Hits	368	Target Neighborhood Hits	192	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

CORO7_HUMAN
NC score	0.392721 (rank : 209)	θ value	6.88961 (rank : 310)
Query Neighborhood Hits	368	Target Neighborhood Hits	315	Shared Neighborhood Hits	187
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

AHI1_HUMAN
NC score	0.391564 (rank : 210)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	368	Target Neighborhood Hits	537	Shared Neighborhood Hits	175
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

STTP1_HUMAN
NC score	0.391476 (rank : 211)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	368	Target Neighborhood Hits	232	Shared Neighborhood Hits	168
SwissProt Accessions	Q6IA86, Q53GZ0, Q687Y8, Q8N5C2, Q96GV4, Q96PI7, Q9H9N0, Q9NV81	Gene names	STATIP1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1) (SHINC-2).

NUP43_HUMAN
NC score	0.389567 (rank : 212)	θ value	0.00869519 (rank : 114)
Query Neighborhood Hits	368	Target Neighborhood Hits	198	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NFH3, Q9H8S0	Gene names	NUP43
Domain Architecture
Description	Nucleoporin Nup43 (p42).

SEC13_MOUSE
NC score	0.386439 (rank : 213)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	368	Target Neighborhood Hits	195	Shared Neighborhood Hits	136
SwissProt Accessions	Q9D1M0, Q99M12, Q9D712	Gene names	Sec13l1
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

SEC13_HUMAN
NC score	0.379841 (rank : 214)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	368	Target Neighborhood Hits	199	Shared Neighborhood Hits	138
SwissProt Accessions	P55735, Q9BRM6, Q9BUG7	Gene names	SEC13L1, SEC13R
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

TLE4_MOUSE
NC score	0.379159 (rank : 215)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	368	Target Neighborhood Hits	482	Shared Neighborhood Hits	218
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE2_HUMAN
NC score	0.379148 (rank : 216)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	368	Target Neighborhood Hits	321	Shared Neighborhood Hits	193
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

TLE4_HUMAN
NC score	0.378881 (rank : 217)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	368	Target Neighborhood Hits	477	Shared Neighborhood Hits	217
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

WDR13_HUMAN
NC score	0.378516 (rank : 218)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	368	Target Neighborhood Hits	186	Shared Neighborhood Hits	139
SwissProt Accessions	Q9H1Z4, Q9BUL7, Q9NWW4	Gene names	WDR13
Domain Architecture
Description	WD repeat protein 13.

TLE2_MOUSE
NC score	0.378371 (rank : 219)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	189
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

EMAL1_HUMAN
NC score	0.375740 (rank : 220)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	368	Target Neighborhood Hits	214	Shared Neighborhood Hits	155
SwissProt Accessions	O00423	Gene names	EML1, EMAP1, EMAPL, EMAPL1
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1).

EMAL4_HUMAN
NC score	0.375736 (rank : 221)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	168
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

TLE3_MOUSE
NC score	0.374759 (rank : 222)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	368	Target Neighborhood Hits	378	Shared Neighborhood Hits	197
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

TLE3_HUMAN
NC score	0.373022 (rank : 223)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	368	Target Neighborhood Hits	385	Shared Neighborhood Hits	200
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

WDR13_MOUSE
NC score	0.370016 (rank : 224)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	368	Target Neighborhood Hits	195	Shared Neighborhood Hits	143
SwissProt Accessions	Q91V09	Gene names	Wdr13
Domain Architecture
Description	WD repeat protein 13.

TLE1_MOUSE
NC score	0.369088 (rank : 225)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	368	Target Neighborhood Hits	491	Shared Neighborhood Hits	229
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TLE1_HUMAN
NC score	0.367830 (rank : 226)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	368	Target Neighborhood Hits	485	Shared Neighborhood Hits	218
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

FBXW8_MOUSE
NC score	0.350936 (rank : 227)	θ value	0.00509761 (rank : 106)
Query Neighborhood Hits	368	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

WDR24_HUMAN
NC score	0.350167 (rank : 228)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	368	Target Neighborhood Hits	247	Shared Neighborhood Hits	152
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WD21C_HUMAN
NC score	0.350166 (rank : 229)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	368	Target Neighborhood Hits	157	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

WDR72_HUMAN
NC score	0.348091 (rank : 230)	θ value	0.0330416 (rank : 141)
Query Neighborhood Hits	368	Target Neighborhood Hits	167	Shared Neighborhood Hits	123
SwissProt Accessions	Q3MJ13, Q7Z3I3, Q8N8X2	Gene names	WDR72
Domain Architecture	No domain graphic available
Description	WD repeat protein 72.

WDR81_MOUSE
NC score	0.347273 (rank : 231)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	368	Target Neighborhood Hits	228	Shared Neighborhood Hits	158
SwissProt Accessions	Q5ND34, Q3TA90, Q3TUS9, Q6KAR1	Gene names	Wdr81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

COR1A_MOUSE
NC score	0.342702 (rank : 232)	θ value	0.0563607 (rank : 147)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	158
SwissProt Accessions	O89053, Q7TMU0, Q9R1Y8, Q9R288	Gene names	Coro1a, Coro1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

CORO6_MOUSE
NC score	0.341877 (rank : 233)	θ value	3.0926 (rank : 263)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	161
SwissProt Accessions	Q920M5, Q920M3, Q920M4	Gene names	Coro6
Domain Architecture	No domain graphic available
Description	Coronin-6 (Clipin E).

DMWD_MOUSE
NC score	0.341672 (rank : 234)	θ value	6.88961 (rank : 311)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	153
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

NPC1_MOUSE
NC score	0.339689 (rank : 235)	θ value	6.85773e-16 (rank : 4)
Query Neighborhood Hits	368	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	O35604, O35605	Gene names	Npc1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

NPC1_HUMAN
NC score	0.339414 (rank : 236)	θ value	3.40345e-15 (rank : 5)
Query Neighborhood Hits	368	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	O15118, Q9P130	Gene names	NPC1
Domain Architecture
Description	Niemann-Pick C1 protein precursor.

COR1A_HUMAN
NC score	0.337632 (rank : 237)	θ value	0.0961366 (rank : 155)
Query Neighborhood Hits	368	Target Neighborhood Hits	240	Shared Neighborhood Hits	161
SwissProt Accessions	P31146	Gene names	CORO1A, CORO1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

COR2B_HUMAN
NC score	0.337046 (rank : 238)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	368	Target Neighborhood Hits	233	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UQ03, O94767, Q8TAN1	Gene names	CORO2B, KIAA0925
Domain Architecture
Description	Coronin-2B (Coronin-like protein C) (ClipinC) (Protein FC96).

COR2B_MOUSE
NC score	0.334648 (rank : 239)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	368	Target Neighborhood Hits	235	Shared Neighborhood Hits	164
SwissProt Accessions	Q8BH44, Q6P5U9	Gene names	Coro2b
Domain Architecture	No domain graphic available
Description	Coronin-2B.

WDR20_MOUSE
NC score	0.334110 (rank : 240)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	368	Target Neighborhood Hits	217	Shared Neighborhood Hits	144
SwissProt Accessions	Q9D5R2	Gene names	Wdr20
Domain Architecture
Description	WD repeat protein 20.

SEH1L_HUMAN
NC score	0.333165 (rank : 241)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	368	Target Neighborhood Hits	145	Shared Neighborhood Hits	103
SwissProt Accessions	Q96EE3, Q8NFU6, Q96MH3, Q9C069	Gene names	SEH1L, SEC13L, SEH1
Domain Architecture
Description	Nucleoporin SEH1-like (SEC13-like protein).

PREB_HUMAN
NC score	0.329473 (rank : 242)	θ value	0.813845 (rank : 202)
Query Neighborhood Hits	368	Target Neighborhood Hits	163	Shared Neighborhood Hits	129
SwissProt Accessions	Q9HCU5, Q9UH94	Gene names	PREB, SEC12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

COR1C_MOUSE
NC score	0.324151 (rank : 243)	θ value	0.279714 (rank : 172)
Query Neighborhood Hits	368	Target Neighborhood Hits	251	Shared Neighborhood Hits	161
SwissProt Accessions	Q9WUM4, Q8VCQ5	Gene names	Coro1c
Domain Architecture
Description	Coronin-1C (Coronin-3).

COR1C_HUMAN
NC score	0.323745 (rank : 244)	θ value	0.279714 (rank : 171)
Query Neighborhood Hits	368	Target Neighborhood Hits	246	Shared Neighborhood Hits	160
SwissProt Accessions	Q9ULV4, Q9NSK5	Gene names	CORO1C, CRNN4
Domain Architecture
Description	Coronin-1C (Coronin-3) (hCRNN4).

DMXL2_HUMAN
NC score	0.323540 (rank : 245)	θ value	4.03905 (rank : 276)
Query Neighborhood Hits	368	Target Neighborhood Hits	374	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

PREB_MOUSE
NC score	0.320862 (rank : 246)	θ value	0.21417 (rank : 169)
Query Neighborhood Hits	368	Target Neighborhood Hits	156	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WUQ2, Q9QZ99	Gene names	Preb, Sec12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

WDR20_HUMAN
NC score	0.320660 (rank : 247)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	368	Target Neighborhood Hits	249	Shared Neighborhood Hits	141
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

IFT80_MOUSE
NC score	0.315145 (rank : 248)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	132
SwissProt Accessions	Q8K057	Gene names	Ift80, Wdr56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

NUP37_MOUSE
NC score	0.312862 (rank : 249)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	368	Target Neighborhood Hits	159	Shared Neighborhood Hits	124
SwissProt Accessions	Q9CWU9	Gene names	Nup37
Domain Architecture
Description	Nucleoporin Nup37.

IFT80_HUMAN
NC score	0.311801 (rank : 250)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	368	Target Neighborhood Hits	195	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P2H3	Gene names	IFT80, KIAA1374, WDR56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

WDR81_HUMAN
NC score	0.309349 (rank : 251)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	368	Target Neighborhood Hits	205	Shared Neighborhood Hits	141
SwissProt Accessions	Q562E7, Q24JP6, Q8N277, Q8N3F3	Gene names	WDR81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

DDB2_MOUSE
NC score	0.305772 (rank : 252)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	368	Target Neighborhood Hits	175	Shared Neighborhood Hits	123
SwissProt Accessions	Q99J79	Gene names	Ddb2
Domain Architecture	No domain graphic available
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2).

COR1B_MOUSE
NC score	0.304816 (rank : 253)	θ value	1.81305 (rank : 234)
Query Neighborhood Hits	368	Target Neighborhood Hits	235	Shared Neighborhood Hits	152
SwissProt Accessions	Q9WUM3, Q3UEB1, Q9CVA2	Gene names	Coro1b
Domain Architecture
Description	Coronin-1B (Coronin-2).

COR1B_HUMAN
NC score	0.304263 (rank : 254)	θ value	5.27518 (rank : 292)
Query Neighborhood Hits	368	Target Neighborhood Hits	239	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BR76	Gene names	CORO1B
Domain Architecture
Description	Coronin-1B (Coronin-2).

NUP37_HUMAN
NC score	0.302797 (rank : 255)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	368	Target Neighborhood Hits	153	Shared Neighborhood Hits	116
SwissProt Accessions	Q8NFH4, Q9H644	Gene names	NUP37
Domain Architecture
Description	Nucleoporin Nup37 (p37).

COR2A_HUMAN
NC score	0.301563 (rank : 256)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	368	Target Neighborhood Hits	214	Shared Neighborhood Hits	144
SwissProt Accessions	Q92828, Q92829, Q9BWS5	Gene names	CORO2A, IR10, WDR2
Domain Architecture
Description	Coronin-2A (WD repeat-containing protein 2) (IR10).

DDB2_HUMAN
NC score	0.301068 (rank : 257)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	368	Target Neighborhood Hits	175	Shared Neighborhood Hits	118
SwissProt Accessions	Q92466, Q76E54, Q76E55, Q76E56, Q76E57	Gene names	DDB2
Domain Architecture
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2) (DDB p48 subunit) (DDBb) (UV-damaged DNA-binding protein 2) (UV-DDB 2).

DMXL1_MOUSE
NC score	0.299544 (rank : 258)	θ value	6.88961 (rank : 312)
Query Neighborhood Hits	368	Target Neighborhood Hits	257	Shared Neighborhood Hits	161
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

KI21B_HUMAN
NC score	0.292951 (rank : 259)	θ value	0.0736092 (rank : 154)
Query Neighborhood Hits	368	Target Neighborhood Hits	1017	Shared Neighborhood Hits	203
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

NPCL1_MOUSE
NC score	0.292011 (rank : 260)	θ value	2.61198e-07 (rank : 18)
Query Neighborhood Hits	368	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q6T3U4, Q5SVX1	Gene names	Npc1l1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

NPCL1_HUMAN
NC score	0.291826 (rank : 261)	θ value	1.99992e-07 (rank : 17)
Query Neighborhood Hits	368	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHC9, Q6R3Q4, Q9UHC8	Gene names	NPC1L1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

KI21B_MOUSE
NC score	0.288796 (rank : 262)	θ value	0.0431538 (rank : 142)
Query Neighborhood Hits	368	Target Neighborhood Hits	997	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

COR2A_MOUSE
NC score	0.286378 (rank : 263)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	368	Target Neighborhood Hits	204	Shared Neighborhood Hits	132
SwissProt Accessions	Q8C0P5, Q3U6H8, Q8BW42	Gene names	Coro2a
Domain Architecture	No domain graphic available
Description	Coronin-2A.

WD21A_HUMAN
NC score	0.282077 (rank : 264)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	368	Target Neighborhood Hits	136	Shared Neighborhood Hits	114
SwissProt Accessions	Q8WV16, Q86U31, Q96K22, Q9Y4P5	Gene names	WDR21A, WDR21
Domain Architecture
Description	WD repeat protein 21A.

LYST_HUMAN
NC score	0.276178 (rank : 265)	θ value	1.06291 (rank : 205)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	133
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

KI21A_HUMAN
NC score	0.275950 (rank : 266)	θ value	0.0330416 (rank : 140)
Query Neighborhood Hits	368	Target Neighborhood Hits	1543	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

WDFY3_HUMAN
NC score	0.275261 (rank : 267)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	368	Target Neighborhood Hits	348	Shared Neighborhood Hits	166
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

KI21A_MOUSE
NC score	0.274750 (rank : 268)	θ value	0.125558 (rank : 159)
Query Neighborhood Hits	368	Target Neighborhood Hits	1317	Shared Neighborhood Hits	203
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

TLE6_MOUSE
NC score	0.273990 (rank : 269)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	368	Target Neighborhood Hits	178	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

WDFY3_MOUSE
NC score	0.273701 (rank : 270)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	368	Target Neighborhood Hits	332	Shared Neighborhood Hits	170
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

PTC2_MOUSE
NC score	0.272653 (rank : 271)	θ value	1.06045e-08 (rank : 13)
Query Neighborhood Hits	368	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O35595, Q546T0	Gene names	Ptch2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

PTC2_HUMAN
NC score	0.268500 (rank : 272)	θ value	1.17247e-07 (rank : 14)
Query Neighborhood Hits	368	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

CIR1A_HUMAN
NC score	0.267225 (rank : 273)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	368	Target Neighborhood Hits	158	Shared Neighborhood Hits	107
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

CIR1A_MOUSE
NC score	0.265417 (rank : 274)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	368	Target Neighborhood Hits	155	Shared Neighborhood Hits	104
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

TSCC1_MOUSE
NC score	0.264569 (rank : 275)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	368	Target Neighborhood Hits	160	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K0G5	Gene names	Tssc1
Domain Architecture	No domain graphic available
Description	Protein TSSC1.

WDR4_MOUSE
NC score	0.263184 (rank : 276)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	368	Target Neighborhood Hits	136	Shared Neighborhood Hits	103
SwissProt Accessions	Q9EP82	Gene names	Wdr4
Domain Architecture
Description	WD repeat protein 4.

WDR4_HUMAN
NC score	0.261754 (rank : 277)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	368	Target Neighborhood Hits	145	Shared Neighborhood Hits	108
SwissProt Accessions	P57081, Q9HCR3	Gene names	WDR4
Domain Architecture
Description	WD repeat protein 4.

PTC1_HUMAN
NC score	0.261434 (rank : 278)	θ value	1.69304e-06 (rank : 31)
Query Neighborhood Hits	368	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

PTC1_MOUSE
NC score	0.261342 (rank : 279)	θ value	1.69304e-06 (rank : 32)
Query Neighborhood Hits	368	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

LYST_MOUSE
NC score	0.258261 (rank : 280)	θ value	1.81305 (rank : 235)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	134
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

TSSC1_HUMAN
NC score	0.256940 (rank : 281)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	368	Target Neighborhood Hits	157	Shared Neighborhood Hits	104
SwissProt Accessions	Q53HC9, O43179, Q53S19, Q53SG2	Gene names	TSSC1
Domain Architecture	No domain graphic available
Description	Protein TSSC1 (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein) (Tumor-suppressing STF cDNA 1 protein).

DMXL1_HUMAN
NC score	0.253680 (rank : 282)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	368	Target Neighborhood Hits	259	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

AAAS_HUMAN
NC score	0.251331 (rank : 283)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	368	Target Neighborhood Hits	154	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NRG9, Q9NWI6, Q9UG19	Gene names	AAAS, ADRACALA
Domain Architecture
Description	Aladin (Adracalin).

FBXW5_MOUSE
NC score	0.249806 (rank : 284)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	368	Target Neighborhood Hits	159	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

UTP18_HUMAN
NC score	0.248292 (rank : 285)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

WDR46_HUMAN
NC score	0.243314 (rank : 286)	θ value	1.06291 (rank : 214)
Query Neighborhood Hits	368	Target Neighborhood Hits	147	Shared Neighborhood Hits	95
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

FBXW5_HUMAN
NC score	0.238214 (rank : 287)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	368	Target Neighborhood Hits	156	Shared Neighborhood Hits	100
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

NBEAL_HUMAN
NC score	0.232401 (rank : 288)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	139
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

WDR67_MOUSE
NC score	0.232044 (rank : 289)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	368	Target Neighborhood Hits	476	Shared Neighborhood Hits	103
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

WDR46_MOUSE
NC score	0.223341 (rank : 290)	θ value	0.279714 (rank : 177)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WDR85_HUMAN
NC score	0.220217 (rank : 291)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	368	Target Neighborhood Hits	134	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BTV6, Q96AB7	Gene names	WDR85, C9orf112
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

AAAS_MOUSE
NC score	0.210690 (rank : 292)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	368	Target Neighborhood Hits	144	Shared Neighborhood Hits	104
SwissProt Accessions	P58742, Q544M6	Gene names	Aaas
Domain Architecture
Description	Aladin (Adracalin).

ARC1B_HUMAN
NC score	0.205470 (rank : 293)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	368	Target Neighborhood Hits	148	Shared Neighborhood Hits	109
SwissProt Accessions	O15143, Q9BU00	Gene names	ARPC1B, ARC41
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

UTP18_MOUSE
NC score	0.200500 (rank : 294)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q5SSI6	Gene names	Utp18, Wdr50
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

WDR54_MOUSE
NC score	0.196249 (rank : 295)	θ value	0.813845 (rank : 203)
Query Neighborhood Hits	368	Target Neighborhood Hits	96	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

HMDH_HUMAN
NC score	0.195804 (rank : 296)	θ value	7.59969e-07 (rank : 24)
Query Neighborhood Hits	368	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	P04035, Q8N190	Gene names	HMGCR
Domain Architecture
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

HMDH_MOUSE
NC score	0.194620 (rank : 297)	θ value	9.92553e-07 (rank : 28)
Query Neighborhood Hits	368	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q01237, Q5U4I2	Gene names	Hmgcr
Domain Architecture	No domain graphic available
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

ARC1B_MOUSE
NC score	0.192230 (rank : 298)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	368	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WV32	Gene names	Arpc1b
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

WDR67_HUMAN
NC score	0.189991 (rank : 299)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	368	Target Neighborhood Hits	782	Shared Neighborhood Hits	123
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

WDR68_HUMAN
NC score	0.186656 (rank : 300)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	368	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	P61962, O15491, Q9DAE4	Gene names	WDR68, HAN11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

WDR68_MOUSE
NC score	0.186656 (rank : 301)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	368	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	P61963, O15491, Q3TMV9, Q9DAE4	Gene names	Wdr68, Han11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

RPTOR_HUMAN
NC score	0.175479 (rank : 302)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	368	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

DNAI2_HUMAN
NC score	0.161842 (rank : 303)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	368	Target Neighborhood Hits	156	Shared Neighborhood Hits	84
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

RPTOR_MOUSE
NC score	0.159256 (rank : 304)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	368	Target Neighborhood Hits	129	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

DNAI1_HUMAN
NC score	0.158543 (rank : 305)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	368	Target Neighborhood Hits	148	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UI46, Q9UEZ8	Gene names	DNAI1
Domain Architecture
Description	Dynein intermediate chain 1, axonemal (Axonemal dynein intermediate chain 1).

TLE6_HUMAN
NC score	0.157628 (rank : 306)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	368	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

NBEA_HUMAN
NC score	0.157512 (rank : 307)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	368	Target Neighborhood Hits	186	Shared Neighborhood Hits	106
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

ARC1A_HUMAN
NC score	0.156803 (rank : 308)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	368	Target Neighborhood Hits	113	Shared Neighborhood Hits	79
SwissProt Accessions	Q92747, Q7Z5U8, Q86WU5, Q8IXQ0	Gene names	ARPC1A, SOP2L
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein).

NBEA_MOUSE
NC score	0.156649 (rank : 309)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	104
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

WDR74_HUMAN
NC score	0.156313 (rank : 310)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	368	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q6RFH5, Q9BRC9, Q9H6X8, Q9NVY2	Gene names	WDR74, NSA1
Domain Architecture	No domain graphic available
Description	WD repeat protein 74 (NOP seven-associated protein 1).

DC1I2_MOUSE
NC score	0.154063 (rank : 311)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	368	Target Neighborhood Hits	209	Shared Neighborhood Hits	98
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

ARC1A_MOUSE
NC score	0.154032 (rank : 312)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	368	Target Neighborhood Hits	120	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0Q6, Q3UL75	Gene names	Arpc1a, Sid329
Domain Architecture	No domain graphic available
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329).

BRWD2_HUMAN
NC score	0.152991 (rank : 313)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	368	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BZH6, Q5VWA1	Gene names	BRWD2, WDR11
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 2 (WD repeat protein 11).

LRBA_HUMAN
NC score	0.152004 (rank : 314)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	368	Target Neighborhood Hits	196	Shared Neighborhood Hits	91
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

DC1I2_HUMAN
NC score	0.149909 (rank : 315)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	368	Target Neighborhood Hits	201	Shared Neighborhood Hits	96
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

WDR85_MOUSE
NC score	0.142598 (rank : 316)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	368	Target Neighborhood Hits	108	Shared Neighborhood Hits	76
SwissProt Accessions	Q9CYU6, Q5RJV7, Q8BIT9	Gene names	Wdr85
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

PI3R4_HUMAN
NC score	0.140891 (rank : 317)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	368	Target Neighborhood Hits	534	Shared Neighborhood Hits	114
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

WDR54_HUMAN
NC score	0.140156 (rank : 318)	θ value	0.62314 (rank : 195)
Query Neighborhood Hits	368	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H977, Q53H85, Q86V45	Gene names	WDR54
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

PI3R4_MOUSE
NC score	0.134742 (rank : 319)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	368	Target Neighborhood Hits	535	Shared Neighborhood Hits	113
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

PPWD1_HUMAN
NC score	0.128481 (rank : 320)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	368	Target Neighborhood Hits	136	Shared Neighborhood Hits	90
SwissProt Accessions	Q96BP3, Q15002, Q7KZ89	Gene names	PPWD1, KIAA0073
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PPWD1_MOUSE
NC score	0.124000 (rank : 321)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	89
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

WDR74_MOUSE
NC score	0.123510 (rank : 322)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	368	Target Neighborhood Hits	70	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VCG3	Gene names	Wdr74
Domain Architecture	No domain graphic available
Description	WD repeat protein 74.

WDR35_HUMAN
NC score	0.122038 (rank : 323)	θ value	1.06291 (rank : 213)
Query Neighborhood Hits	368	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

DC1I1_HUMAN
NC score	0.120585 (rank : 324)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	368	Target Neighborhood Hits	183	Shared Neighborhood Hits	82
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

DC1I1_MOUSE
NC score	0.117371 (rank : 325)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	368	Target Neighborhood Hits	206	Shared Neighborhood Hits	86
SwissProt Accessions	O88485, O88486	Gene names	Dync1i1, Dnci1, Dncic1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

WDR8_HUMAN
NC score	0.114013 (rank : 326)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	368	Target Neighborhood Hits	69	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2S5, Q5T0D6, Q9BUH7, Q9NTK7, Q9NX56	Gene names	WDR8
Domain Architecture
Description	WD repeat protein 8.

WDR34_MOUSE
NC score	0.107616 (rank : 327)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	368	Target Neighborhood Hits	105	Shared Neighborhood Hits	63
SwissProt Accessions	Q5U4F6	Gene names	Wdr34
Domain Architecture	No domain graphic available
Description	WD repeat protein 34.

WDR8_MOUSE
NC score	0.107489 (rank : 328)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	368	Target Neighborhood Hits	71	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JM98	Gene names	Wdr8, Dd57
Domain Architecture
Description	WD repeat protein 8.

WDR35_MOUSE
NC score	0.098027 (rank : 329)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	368	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

FBX16_HUMAN
NC score	0.097512 (rank : 330)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	368	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

WDR34_HUMAN
NC score	0.095261 (rank : 331)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	368	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q96EX3, Q5VXV4, Q9BV46	Gene names	WDR34
Domain Architecture
Description	WD repeat protein 34.

STXB5_HUMAN
NC score	0.092689 (rank : 332)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	368	Target Neighborhood Hits	167	Shared Neighborhood Hits	96
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

FBX16_MOUSE
NC score	0.090987 (rank : 333)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	368	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

STB5L_MOUSE
NC score	0.087064 (rank : 334)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	368	Target Neighborhood Hits	138	Shared Neighborhood Hits	77
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STB5L_HUMAN
NC score	0.086683 (rank : 335)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

TULP4_HUMAN
NC score	0.084237 (rank : 336)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	368	Target Neighborhood Hits	426	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

STXB5_MOUSE
NC score	0.083329 (rank : 337)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	368	Target Neighborhood Hits	161	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

TULP4_MOUSE
NC score	0.074275 (rank : 338)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	368	Target Neighborhood Hits	247	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TR95_MOUSE
NC score	0.072986 (rank : 339)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	368	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PGF3	Gene names	Thrap5
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

TF3C2_MOUSE
NC score	0.072439 (rank : 340)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	368	Target Neighborhood Hits	165	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

WIPI1_MOUSE
NC score	0.067280 (rank : 341)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	368	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R3E3, Q8BGE1, Q8R1A9, Q8R1C7	Gene names	Wipi1, D11Ertd498e
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa).

IF140_HUMAN
NC score	0.067260 (rank : 342)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	368	Target Neighborhood Hits	111	Shared Neighborhood Hits	47
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

TF3C2_HUMAN
NC score	0.064063 (rank : 343)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	368	Target Neighborhood Hits	168	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

WDR76_HUMAN
NC score	0.063314 (rank : 344)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	368	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H967	Gene names	WDR76
Domain Architecture	No domain graphic available
Description	WD repeat protein 76.

WIPI1_HUMAN
NC score	0.059261 (rank : 345)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	368	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q5MNZ9, Q8IXM5, Q9NWF8	Gene names	WIPI1, WIPI49
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa) (Atg18 protein homolog).

FA47A_HUMAN
NC score	0.056555 (rank : 346)	θ value	0.163984 (rank : 164)
Query Neighborhood Hits	368	Target Neighborhood Hits	451	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

WDR19_HUMAN
NC score	0.055676 (rank : 347)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	368	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NEZ3, Q8N5B4, Q9H5S0, Q9HCD4	Gene names	WDR19, KIAA1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

WIPI3_MOUSE
NC score	0.054592 (rank : 348)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	368	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CR39, Q3U924	Gene names	Wdr45l, Wipi3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein).

WIPI3_HUMAN
NC score	0.054287 (rank : 349)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	368	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q5MNZ6, O95328, Q6IBN2	Gene names	WDR45L, WIPI3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein) (WIPI49-like protein).

WDR19_MOUSE
NC score	0.054162 (rank : 350)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	368	Target Neighborhood Hits	83	Shared Neighborhood Hits	41
SwissProt Accessions	Q3UGF1, Q6ZPK8, Q80VQ6, Q8C794, Q8K3R5	Gene names	Wdr19, Kiaa1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

WASL_MOUSE
NC score	0.053279 (rank : 351)	θ value	0.0961366 (rank : 158)
Query Neighborhood Hits	368	Target Neighborhood Hits	339	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

NOL10_MOUSE
NC score	0.051159 (rank : 352)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	368	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

YLPM1_HUMAN
NC score	0.049133 (rank : 353)	θ value	0.47712 (rank : 192)
Query Neighborhood Hits	368	Target Neighborhood Hits	670	Shared Neighborhood Hits	53
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ETV5_MOUSE
NC score	0.048441 (rank : 354)	θ value	0.0113563 (rank : 117)
Query Neighborhood Hits	368	Target Neighborhood Hits	328	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

PELP1_MOUSE
NC score	0.048170 (rank : 355)	θ value	2.36792 (rank : 253)
Query Neighborhood Hits	368	Target Neighborhood Hits	709	Shared Neighborhood Hits	67
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SMR3A_HUMAN
NC score	0.046536 (rank : 356)	θ value	1.38821 (rank : 229)
Query Neighborhood Hits	368	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

CS007_MOUSE
NC score	0.046178 (rank : 357)	θ value	0.279714 (rank : 173)
Query Neighborhood Hits	368	Target Neighborhood Hits	464	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DIAP1_MOUSE
NC score	0.045396 (rank : 358)	θ value	0.0193708 (rank : 128)
Query Neighborhood Hits	368	Target Neighborhood Hits	839	Shared Neighborhood Hits	36
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

CS007_HUMAN
NC score	0.045202 (rank : 359)	θ value	0.21417 (rank : 168)
Query Neighborhood Hits	368	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DIAP1_HUMAN
NC score	0.045030 (rank : 360)	θ value	0.279714 (rank : 174)
Query Neighborhood Hits	368	Target Neighborhood Hits	784	Shared Neighborhood Hits	37
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

ETV5_HUMAN
NC score	0.042710 (rank : 361)	θ value	0.0193708 (rank : 129)
Query Neighborhood Hits	368	Target Neighborhood Hits	181	Shared Neighborhood Hits	23
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

BAT2_HUMAN
NC score	0.042271 (rank : 362)	θ value	0.62314 (rank : 193)
Query Neighborhood Hits	368	Target Neighborhood Hits	931	Shared Neighborhood Hits	74
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DAAM1_HUMAN
NC score	0.042063 (rank : 363)	θ value	0.163984 (rank : 163)
Query Neighborhood Hits	368	Target Neighborhood Hits	483	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

PELP1_HUMAN
NC score	0.041701 (rank : 364)	θ value	0.365318 (rank : 186)
Query Neighborhood Hits	368	Target Neighborhood Hits	596	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

FMNL_HUMAN
NC score	0.039305 (rank : 365)	θ value	3.0926 (rank : 264)
Query Neighborhood Hits	368	Target Neighborhood Hits	529	Shared Neighborhood Hits	41
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

ARI1A_HUMAN
NC score	0.037701 (rank : 366)	θ value	0.813845 (rank : 196)
Query Neighborhood Hits	368	Target Neighborhood Hits	787	Shared Neighborhood Hits	74
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

YLPM1_MOUSE
NC score	0.037471 (rank : 367)	θ value	1.81305 (rank : 242)
Query Neighborhood Hits	368	Target Neighborhood Hits	505	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

FMN2_HUMAN
NC score	0.036938 (rank : 368)	θ value	1.38821 (rank : 217)
Query Neighborhood Hits	368	Target Neighborhood Hits	484	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GRIN2_HUMAN
NC score	0.036753 (rank : 369)	θ value	1.38821 (rank : 219)
Query Neighborhood Hits	368	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

SC24A_MOUSE
NC score	0.036725 (rank : 370)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	368	Target Neighborhood Hits	394	Shared Neighborhood Hits	68
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

WASP_MOUSE
NC score	0.036681 (rank : 371)	θ value	4.03905 (rank : 289)
Query Neighborhood Hits	368	Target Neighborhood Hits	223	Shared Neighborhood Hits	24
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

SF01_HUMAN
NC score	0.036308 (rank : 372)	θ value	1.38821 (rank : 226)
Query Neighborhood Hits	368	Target Neighborhood Hits	287	Shared Neighborhood Hits	24
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

EP300_HUMAN
NC score	0.036118 (rank : 373)	θ value	4.03905 (rank : 277)
Query Neighborhood Hits	368	Target Neighborhood Hits	821	Shared Neighborhood Hits	68
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FMNL_MOUSE
NC score	0.036060 (rank : 374)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	368	Target Neighborhood Hits	428	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

SF01_MOUSE
NC score	0.036056 (rank : 375)	θ value	1.38821 (rank : 227)
Query Neighborhood Hits	368	Target Neighborhood Hits	240	Shared Neighborhood Hits	18
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

BAT2_MOUSE
NC score	0.035846 (rank : 376)	θ value	4.03905 (rank : 273)
Query Neighborhood Hits	368	Target Neighborhood Hits	947	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CA156_MOUSE
NC score	0.034843 (rank : 377)	θ value	0.813845 (rank : 197)
Query Neighborhood Hits	368	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZ09, Q810I8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf156 homolog.

WASP_HUMAN
NC score	0.033986 (rank : 378)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	368	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASL_HUMAN
NC score	0.033804 (rank : 379)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

IASPP_MOUSE
NC score	0.033543 (rank : 380)	θ value	0.0736092 (rank : 153)
Query Neighborhood Hits	368	Target Neighborhood Hits	1024	Shared Neighborhood Hits	74
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

DAAM2_HUMAN
NC score	0.033008 (rank : 381)	θ value	5.27518 (rank : 293)
Query Neighborhood Hits	368	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

RNC_HUMAN
NC score	0.032590 (rank : 382)	θ value	1.38821 (rank : 224)
Query Neighborhood Hits	368	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

CPSF6_MOUSE
NC score	0.032455 (rank : 383)	θ value	2.36792 (rank : 247)
Query Neighborhood Hits	368	Target Neighborhood Hits	356	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CPSF6_HUMAN
NC score	0.032447 (rank : 384)	θ value	2.36792 (rank : 246)
Query Neighborhood Hits	368	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

LCP2_HUMAN
NC score	0.032081 (rank : 385)	θ value	3.0926 (rank : 267)
Query Neighborhood Hits	368	Target Neighborhood Hits	531	Shared Neighborhood Hits	60
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PCLO_MOUSE
NC score	0.031459 (rank : 386)	θ value	1.06291 (rank : 207)
Query Neighborhood Hits	368	Target Neighborhood Hits	2275	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CRTC1_HUMAN
NC score	0.030637 (rank : 387)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	368	Target Neighborhood Hits	319	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

BSN_MOUSE
NC score	0.030143 (rank : 388)	θ value	6.88961 (rank : 308)
Query Neighborhood Hits	368	Target Neighborhood Hits	2057	Shared Neighborhood Hits	127
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CD5R2_HUMAN
NC score	0.029965 (rank : 389)	θ value	3.0926 (rank : 262)
Query Neighborhood Hits	368	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q13319, Q4ZFW6	Gene names	CDK5R2, NCK5AI
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

CD5R2_MOUSE
NC score	0.029650 (rank : 390)	θ value	1.81305 (rank : 233)
Query Neighborhood Hits	368	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

GP108_MOUSE
NC score	0.029258 (rank : 391)	θ value	0.47712 (rank : 188)
Query Neighborhood Hits	368	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

RBBP6_MOUSE
NC score	0.028991 (rank : 392)	θ value	0.62314 (rank : 194)
Query Neighborhood Hits	368	Target Neighborhood Hits	1014	Shared Neighborhood Hits	41
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

EPN1_HUMAN
NC score	0.028960 (rank : 393)	θ value	0.365318 (rank : 183)
Query Neighborhood Hits	368	Target Neighborhood Hits	206	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

CTDP1_HUMAN
NC score	0.028683 (rank : 394)	θ value	2.36792 (rank : 248)
Query Neighborhood Hits	368	Target Neighborhood Hits	416	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

MBD6_HUMAN
NC score	0.027615 (rank : 395)	θ value	3.0926 (rank : 268)
Query Neighborhood Hits	368	Target Neighborhood Hits	349	Shared Neighborhood Hits	29
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

TCGAP_HUMAN
NC score	0.027099 (rank : 396)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	368	Target Neighborhood Hits	872	Shared Neighborhood Hits	92
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SMDF_HUMAN
NC score	0.027005 (rank : 397)	θ value	1.81305 (rank : 241)
Query Neighborhood Hits	368	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

PI5PA_HUMAN
NC score	0.026984 (rank : 398)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	368	Target Neighborhood Hits	749	Shared Neighborhood Hits	89
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SFR15_HUMAN
NC score	0.026423 (rank : 399)	θ value	6.88961 (rank : 323)
Query Neighborhood Hits	368	Target Neighborhood Hits	368	Shared Neighborhood Hits	28
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

HES7_MOUSE
NC score	0.026074 (rank : 400)	θ value	1.38821 (rank : 220)
Query Neighborhood Hits	368	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

SF3A2_HUMAN
NC score	0.025816 (rank : 401)	θ value	4.03905 (rank : 285)
Query Neighborhood Hits	368	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

RBM16_HUMAN
NC score	0.025766 (rank : 402)	θ value	3.0926 (rank : 269)
Query Neighborhood Hits	368	Target Neighborhood Hits	300	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

CBL_HUMAN
NC score	0.025749 (rank : 403)	θ value	1.06291 (rank : 204)
Query Neighborhood Hits	368	Target Neighborhood Hits	353	Shared Neighborhood Hits	31
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

TAF4_HUMAN
NC score	0.025399 (rank : 404)	θ value	2.36792 (rank : 257)
Query Neighborhood Hits	368	Target Neighborhood Hits	687	Shared Neighborhood Hits	41
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

SPHK2_MOUSE
NC score	0.025309 (rank : 405)	θ value	1.06291 (rank : 208)
Query Neighborhood Hits	368	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

WASF4_HUMAN
NC score	0.024831 (rank : 406)	θ value	1.38821 (rank : 230)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

CABIN_HUMAN
NC score	0.024500 (rank : 407)	θ value	8.99809 (rank : 333)
Query Neighborhood Hits	368	Target Neighborhood Hits	490	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CO3A1_MOUSE
NC score	0.024373 (rank : 408)	θ value	0.0563607 (rank : 146)
Query Neighborhood Hits	368	Target Neighborhood Hits	466	Shared Neighborhood Hits	27
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

PRP2_MOUSE
NC score	0.024372 (rank : 409)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	368	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SF3A2_MOUSE
NC score	0.024317 (rank : 410)	θ value	6.88961 (rank : 322)
Query Neighborhood Hits	368	Target Neighborhood Hits	247	Shared Neighborhood Hits	26
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SH22A_HUMAN
NC score	0.023941 (rank : 411)	θ value	1.38821 (rank : 228)
Query Neighborhood Hits	368	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

K0310_HUMAN
NC score	0.023752 (rank : 412)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	368	Target Neighborhood Hits	420	Shared Neighborhood Hits	48
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

RBBP6_HUMAN
NC score	0.023525 (rank : 413)	θ value	0.47712 (rank : 189)
Query Neighborhood Hits	368	Target Neighborhood Hits	1135	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

BAT3_HUMAN
NC score	0.022933 (rank : 414)	θ value	6.88961 (rank : 305)
Query Neighborhood Hits	368	Target Neighborhood Hits	490	Shared Neighborhood Hits	61
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CBL_MOUSE
NC score	0.022561 (rank : 415)	θ value	3.0926 (rank : 261)
Query Neighborhood Hits	368	Target Neighborhood Hits	426	Shared Neighborhood Hits	39
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

ENAH_MOUSE
NC score	0.021953 (rank : 416)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	368	Target Neighborhood Hits	919	Shared Neighborhood Hits	51
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CO3A1_HUMAN
NC score	0.021855 (rank : 417)	θ value	0.365318 (rank : 182)
Query Neighborhood Hits	368	Target Neighborhood Hits	452	Shared Neighborhood Hits	28
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

SMR1_MOUSE
NC score	0.021512 (rank : 418)	θ value	6.88961 (rank : 324)
Query Neighborhood Hits	368	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

BRD4_MOUSE
NC score	0.021450 (rank : 419)	θ value	6.88961 (rank : 307)
Query Neighborhood Hits	368	Target Neighborhood Hits	845	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

HNRL1_HUMAN
NC score	0.021380 (rank : 420)	θ value	5.27518 (rank : 296)
Query Neighborhood Hits	368	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
NC score	0.021219 (rank : 421)	θ value	5.27518 (rank : 297)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

CK036_HUMAN
NC score	0.020820 (rank : 422)	θ value	8.99809 (rank : 336)
Query Neighborhood Hits	368	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q2M3A8, Q6TF48, Q8N7R8, Q8N9X7	Gene names	C11orf36
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf36.

SF3A1_MOUSE
NC score	0.020803 (rank : 423)	θ value	2.36792 (rank : 255)
Query Neighborhood Hits	368	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

AB1IP_HUMAN
NC score	0.020774 (rank : 424)	θ value	2.36792 (rank : 245)
Query Neighborhood Hits	368	Target Neighborhood Hits	213	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

RAPH1_HUMAN
NC score	0.020721 (rank : 425)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	368	Target Neighborhood Hits	593	Shared Neighborhood Hits	46
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PDC6I_MOUSE
NC score	0.020696 (rank : 426)	θ value	4.03905 (rank : 282)
Query Neighborhood Hits	368	Target Neighborhood Hits	275	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

ATN1_HUMAN
NC score	0.019783 (rank : 427)	θ value	6.88961 (rank : 304)
Query Neighborhood Hits	368	Target Neighborhood Hits	676	Shared Neighborhood Hits	40
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

EPN1_MOUSE
NC score	0.019585 (rank : 428)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	368	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

MLL2_HUMAN
NC score	0.019551 (rank : 429)	θ value	2.36792 (rank : 250)
Query Neighborhood Hits	368	Target Neighborhood Hits	1788	Shared Neighborhood Hits	93
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

GSCR1_HUMAN
NC score	0.019428 (rank : 430)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	368	Target Neighborhood Hits	674	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

GFC1_HUMAN
NC score	0.019251 (rank : 431)	θ value	5.27518 (rank : 295)
Query Neighborhood Hits	368	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

KIF1C_MOUSE
NC score	0.019195 (rank : 432)	θ value	5.27518 (rank : 299)
Query Neighborhood Hits	368	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KI13B_HUMAN
NC score	0.018749 (rank : 433)	θ value	4.03905 (rank : 281)
Query Neighborhood Hits	368	Target Neighborhood Hits	492	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

FOXN1_MOUSE
NC score	0.018234 (rank : 434)	θ value	1.38821 (rank : 218)
Query Neighborhood Hits	368	Target Neighborhood Hits	300	Shared Neighborhood Hits	46
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

RIN3_HUMAN
NC score	0.018223 (rank : 435)	θ value	4.03905 (rank : 283)
Query Neighborhood Hits	368	Target Neighborhood Hits	227	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SAM68_HUMAN
NC score	0.017948 (rank : 436)	θ value	6.88961 (rank : 321)
Query Neighborhood Hits	368	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

WASF2_MOUSE
NC score	0.017378 (rank : 437)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	368	Target Neighborhood Hits	315	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

SFPQ_HUMAN
NC score	0.017056 (rank : 438)	θ value	1.81305 (rank : 240)
Query Neighborhood Hits	368	Target Neighborhood Hits	986	Shared Neighborhood Hits	44
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SAM68_MOUSE
NC score	0.016000 (rank : 439)	θ value	8.99809 (rank : 358)
Query Neighborhood Hits	368	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

IRX3_HUMAN
NC score	0.015735 (rank : 440)	θ value	3.0926 (rank : 265)
Query Neighborhood Hits	368	Target Neighborhood Hits	342	Shared Neighborhood Hits	11
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

DOT1L_HUMAN
NC score	0.015548 (rank : 441)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	368	Target Neighborhood Hits	660	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

RERE_MOUSE
NC score	0.015469 (rank : 442)	θ value	8.99809 (rank : 355)
Query Neighborhood Hits	368	Target Neighborhood Hits	785	Shared Neighborhood Hits	54
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TARA_HUMAN
NC score	0.015281 (rank : 443)	θ value	4.03905 (rank : 288)
Query Neighborhood Hits	368	Target Neighborhood Hits	1626	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MAGC1_HUMAN
NC score	0.014850 (rank : 444)	θ value	1.06291 (rank : 206)
Query Neighborhood Hits	368	Target Neighborhood Hits	431	Shared Neighborhood Hits	34
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PTN23_MOUSE
NC score	0.014713 (rank : 445)	θ value	6.88961 (rank : 318)
Query Neighborhood Hits	368	Target Neighborhood Hits	726	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CXXC6_HUMAN
NC score	0.014604 (rank : 446)	θ value	8.99809 (rank : 338)
Query Neighborhood Hits	368	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

HCN2_HUMAN
NC score	0.014130 (rank : 447)	θ value	0.813845 (rank : 199)
Query Neighborhood Hits	368	Target Neighborhood Hits	369	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

RP3A_MOUSE
NC score	0.013758 (rank : 448)	θ value	6.88961 (rank : 319)
Query Neighborhood Hits	368	Target Neighborhood Hits	510	Shared Neighborhood Hits	56
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SMRC1_MOUSE
NC score	0.013744 (rank : 449)	θ value	4.03905 (rank : 286)
Query Neighborhood Hits	368	Target Neighborhood Hits	459	Shared Neighborhood Hits	24
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

AKAP2_HUMAN
NC score	0.013465 (rank : 450)	θ value	6.88961 (rank : 303)
Query Neighborhood Hits	368	Target Neighborhood Hits	507	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

RTN4_HUMAN
NC score	0.013345 (rank : 451)	θ value	4.03905 (rank : 284)
Query Neighborhood Hits	368	Target Neighborhood Hits	357	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

IRX3_MOUSE
NC score	0.012711 (rank : 452)	θ value	4.03905 (rank : 279)
Query Neighborhood Hits	368	Target Neighborhood Hits	303	Shared Neighborhood Hits	10
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

JIP3_MOUSE
NC score	0.012554 (rank : 453)	θ value	4.03905 (rank : 280)
Query Neighborhood Hits	368	Target Neighborhood Hits	759	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

SMCA4_HUMAN
NC score	0.012275 (rank : 454)	θ value	2.36792 (rank : 256)
Query Neighborhood Hits	368	Target Neighborhood Hits	597	Shared Neighborhood Hits	36
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CIC_MOUSE
NC score	0.012192 (rank : 455)	θ value	8.99809 (rank : 335)
Query Neighborhood Hits	368	Target Neighborhood Hits	742	Shared Neighborhood Hits	61
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

RANB3_HUMAN
NC score	0.011955 (rank : 456)	θ value	8.99809 (rank : 354)
Query Neighborhood Hits	368	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

PTN23_HUMAN
NC score	0.011806 (rank : 457)	θ value	6.88961 (rank : 317)
Query Neighborhood Hits	368	Target Neighborhood Hits	646	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

I17RC_HUMAN
NC score	0.011370 (rank : 458)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	368	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NAC3, Q6UVY3, Q6UWD4, Q8NFS1, Q9BR97	Gene names	IL17RC
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor C precursor (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor-like protein) (IL-17RL) (Interleukin-17 receptor homolog) (IL17Rhom).

HRX_HUMAN
NC score	0.011367 (rank : 459)	θ value	6.88961 (rank : 315)
Query Neighborhood Hits	368	Target Neighborhood Hits	825	Shared Neighborhood Hits	45
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IQEC2_MOUSE
NC score	0.010650 (rank : 460)	θ value	4.03905 (rank : 278)
Query Neighborhood Hits	368	Target Neighborhood Hits	417	Shared Neighborhood Hits	29
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

CO7A1_HUMAN
NC score	0.010394 (rank : 461)	θ value	4.03905 (rank : 275)
Query Neighborhood Hits	368	Target Neighborhood Hits	807	Shared Neighborhood Hits	45
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DGKK_HUMAN
NC score	0.010205 (rank : 462)	θ value	5.27518 (rank : 294)
Query Neighborhood Hits	368	Target Neighborhood Hits	378	Shared Neighborhood Hits	17
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

RP3A_HUMAN
NC score	0.010197 (rank : 463)	θ value	3.0926 (rank : 270)
Query Neighborhood Hits	368	Target Neighborhood Hits	305	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

CMTA2_MOUSE
NC score	0.010030 (rank : 464)	θ value	6.88961 (rank : 309)
Query Neighborhood Hits	368	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

IRX5_HUMAN
NC score	0.010016 (rank : 465)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	368	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

ZCHC8_HUMAN
NC score	0.009561 (rank : 466)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	368	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZY4, Q7L2P6, Q8N2K5, Q96SK7, Q9NSS2, Q9NSS3	Gene names	ZCCHC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

CCNK_MOUSE
NC score	0.009535 (rank : 467)	θ value	8.99809 (rank : 334)
Query Neighborhood Hits	368	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

ENV2_MOUSE
NC score	0.009455 (rank : 468)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	368	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

ZMYM3_HUMAN
NC score	0.009168 (rank : 469)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	368	Target Neighborhood Hits	223	Shared Neighborhood Hits	16
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

HD_HUMAN
NC score	0.008684 (rank : 470)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	368	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

COKA1_HUMAN
NC score	0.008438 (rank : 471)	θ value	5.27518 (rank : 291)
Query Neighborhood Hits	368	Target Neighborhood Hits	403	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

MEIS2_MOUSE
NC score	0.007757 (rank : 472)	θ value	5.27518 (rank : 301)
Query Neighborhood Hits	368	Target Neighborhood Hits	208	Shared Neighborhood Hits	14
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

JARD2_MOUSE
NC score	0.007673 (rank : 473)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	368	Target Neighborhood Hits	169	Shared Neighborhood Hits	9
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

FOXB2_MOUSE
NC score	0.007343 (rank : 474)	θ value	2.36792 (rank : 249)
Query Neighborhood Hits	368	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

XYLT1_HUMAN
NC score	0.006994 (rank : 475)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	368	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

HDAC7_HUMAN
NC score	0.005548 (rank : 476)	θ value	6.88961 (rank : 313)
Query Neighborhood Hits	368	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

KCNC3_MOUSE
NC score	0.005445 (rank : 477)	θ value	3.0926 (rank : 266)
Query Neighborhood Hits	368	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

SYT5_HUMAN
NC score	0.005352 (rank : 478)	θ value	4.03905 (rank : 287)
Query Neighborhood Hits	368	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

HNF3G_HUMAN
NC score	0.003882 (rank : 479)	θ value	6.88961 (rank : 314)
Query Neighborhood Hits	368	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	P55318, Q9UMW9	Gene names	FOXA3, HNF3G, TCF3G
Domain Architecture
Description	Hepatocyte nuclear factor 3-gamma (HNF-3G) (Forkhead box protein A3) (Fork head-related protein FKH H3).

PAPPA_HUMAN
NC score	0.003848 (rank : 480)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	368	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

TBX6_MOUSE
NC score	0.003337 (rank : 481)	θ value	6.88961 (rank : 325)
Query Neighborhood Hits	368	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

LTBP4_MOUSE
NC score	0.002944 (rank : 482)	θ value	0.813845 (rank : 200)
Query Neighborhood Hits	368	Target Neighborhood Hits	607	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

KCNA5_HUMAN
NC score	0.002624 (rank : 483)	θ value	6.88961 (rank : 316)
Query Neighborhood Hits	368	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

SOX9_MOUSE
NC score	0.002049 (rank : 484)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	368	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

ANR11_HUMAN
NC score	0.002014 (rank : 485)	θ value	8.99809 (rank : 332)
Query Neighborhood Hits	368	Target Neighborhood Hits	1289	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

BICD1_HUMAN
NC score	0.001555 (rank : 486)	θ value	6.88961 (rank : 306)
Query Neighborhood Hits	368	Target Neighborhood Hits	844	Shared Neighborhood Hits	21
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

NID2_HUMAN
NC score	0.000777 (rank : 487)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	368	Target Neighborhood Hits	456	Shared Neighborhood Hits	30
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

RXRB_HUMAN
NC score	0.000213 (rank : 488)	θ value	6.88961 (rank : 320)
Query Neighborhood Hits	368	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

WNK2_HUMAN
NC score	-0.000799 (rank : 489)	θ value	0.47712 (rank : 191)
Query Neighborhood Hits	368	Target Neighborhood Hits	1407	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CROCC_HUMAN
NC score	-0.001343 (rank : 490)	θ value	8.99809 (rank : 337)
Query Neighborhood Hits	368	Target Neighborhood Hits	1409	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

HXB4_MOUSE
NC score	-0.002440 (rank : 491)	θ value	5.27518 (rank : 298)
Query Neighborhood Hits	368	Target Neighborhood Hits	375	Shared Neighborhood Hits	9
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

AAK1_HUMAN
NC score	-0.003077 (rank : 492)	θ value	2.36792 (rank : 244)
Query Neighborhood Hits	368	Target Neighborhood Hits	1077	Shared Neighborhood Hits	42
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

MAST4_HUMAN
NC score	-0.003694 (rank : 493)	θ value	5.27518 (rank : 300)
Query Neighborhood Hits	368	Target Neighborhood Hits	1804	Shared Neighborhood Hits	79
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ZN295_HUMAN
NC score	-0.003993 (rank : 494)	θ value	1.81305 (rank : 243)
Query Neighborhood Hits	368	Target Neighborhood Hits	847	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

ZN219_HUMAN
NC score	-0.004672 (rank : 495)	θ value	4.03905 (rank : 290)
Query Neighborhood Hits	368	Target Neighborhood Hits	876	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

WNK4_HUMAN
NC score	-0.005137 (rank : 496)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	368	Target Neighborhood Hits	1043	Shared Neighborhood Hits	26
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

PRD16_HUMAN
NC score	-0.005913 (rank : 497)	θ value	1.81305 (rank : 237)
Query Neighborhood Hits	368	Target Neighborhood Hits	832	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

PRD15_HUMAN
NC score	-0.005917 (rank : 498)	θ value	0.813845 (rank : 201)
Query Neighborhood Hits	368	Target Neighborhood Hits	805	Shared Neighborhood Hits	11
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

ZN683_HUMAN
NC score	-0.006421 (rank : 499)	θ value	2.36792 (rank : 259)
Query Neighborhood Hits	368	Target Neighborhood Hits	750	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZ20, Q5T141, Q5T146, Q5T147, Q5T149, Q8NEN4	Gene names	ZNF683
Domain Architecture	No domain graphic available
Description	Zinc finger protein 683.

ZN553_HUMAN
NC score	-0.007704 (rank : 500)	θ value	3.0926 (rank : 272)
Query Neighborhood Hits	368	Target Neighborhood Hits	760	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

TESK1_MOUSE
NC score	-0.007794 (rank : 501)	θ value	3.0926 (rank : 271)
Query Neighborhood Hits	368	Target Neighborhood Hits	862	Shared Neighborhood Hits	10
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

ABL1_MOUSE
NC score	-0.008565 (rank : 502)	θ value	3.0926 (rank : 260)
Query Neighborhood Hits	368	Target Neighborhood Hits	1178	Shared Neighborhood Hits	20
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

TITIN_HUMAN
NC score	-0.010321 (rank : 503)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	368	Target Neighborhood Hits	2923	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).