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Network neighborhood for query Sequence : TBX6_MOUSE

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TBX6_MOUSE
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TBX6_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX6_HUMAN
θ value	7.49059e-172 (rank : 2)	NC score	0.996448 (rank : 2)
Query Neighborhood Hits	54	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX2_HUMAN
θ value	3.71096e-62 (rank : 3)	NC score	0.959638 (rank : 20)
Query Neighborhood Hits	54	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX4_MOUSE
θ value	3.71096e-62 (rank : 4)	NC score	0.968962 (rank : 13)
Query Neighborhood Hits	54	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX5_HUMAN
θ value	1.41016e-61 (rank : 5)	NC score	0.970134 (rank : 8)
Query Neighborhood Hits	54	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
θ value	1.41016e-61 (rank : 6)	NC score	0.969488 (rank : 10)
Query Neighborhood Hits	54	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX2_MOUSE
θ value	1.84173e-61 (rank : 7)	NC score	0.964841 (rank : 15)
Query Neighborhood Hits	54	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX4_HUMAN
θ value	1.84173e-61 (rank : 8)	NC score	0.969245 (rank : 11)
Query Neighborhood Hits	54	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX15_HUMAN
θ value	2.65945e-60 (rank : 9)	NC score	0.964474 (rank : 17)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

TBX18_HUMAN
θ value	5.92465e-60 (rank : 10)	NC score	0.962406 (rank : 18)
Query Neighborhood Hits	54	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX18_MOUSE
θ value	1.7238e-59 (rank : 11)	NC score	0.966203 (rank : 14)
Query Neighborhood Hits	54	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX15_MOUSE
θ value	2.25136e-59 (rank : 12)	NC score	0.964529 (rank : 16)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

TBX20_MOUSE
θ value	1.23536e-57 (rank : 13)	NC score	0.982365 (rank : 3)
Query Neighborhood Hits	54	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

TBX1_HUMAN
θ value	1.51013e-55 (rank : 14)	NC score	0.975732 (rank : 4)
Query Neighborhood Hits	54	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX10_HUMAN
θ value	7.49467e-55 (rank : 15)	NC score	0.973618 (rank : 6)
Query Neighborhood Hits	54	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX3_HUMAN
θ value	9.78833e-55 (rank : 16)	NC score	0.955743 (rank : 24)
Query Neighborhood Hits	54	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX3_MOUSE
θ value	1.2784e-54 (rank : 17)	NC score	0.961390 (rank : 19)
Query Neighborhood Hits	54	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX10_MOUSE
θ value	5.37103e-53 (rank : 18)	NC score	0.973003 (rank : 7)
Query Neighborhood Hits	54	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX1_MOUSE
θ value	5.37103e-53 (rank : 19)	NC score	0.975486 (rank : 5)
Query Neighborhood Hits	54	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX22_HUMAN
θ value	1.19655e-52 (rank : 20)	NC score	0.969747 (rank : 9)
Query Neighborhood Hits	54	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX22_MOUSE
θ value	1.19655e-52 (rank : 21)	NC score	0.969090 (rank : 12)
Query Neighborhood Hits	54	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX21_HUMAN
θ value	8.57503e-51 (rank : 22)	NC score	0.948422 (rank : 27)
Query Neighborhood Hits	54	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

BRAC_MOUSE
θ value	5.55816e-50 (rank : 23)	NC score	0.958820 (rank : 21)
Query Neighborhood Hits	54	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

BRAC_HUMAN
θ value	9.48078e-50 (rank : 24)	NC score	0.957360 (rank : 23)
Query Neighborhood Hits	54	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX19_HUMAN
θ value	1.15895e-47 (rank : 25)	NC score	0.957736 (rank : 22)
Query Neighborhood Hits	54	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX21_MOUSE
θ value	1.97686e-47 (rank : 26)	NC score	0.951315 (rank : 26)
Query Neighborhood Hits	54	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBR1_HUMAN
θ value	4.40402e-47 (rank : 27)	NC score	0.943970 (rank : 28)
Query Neighborhood Hits	54	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_MOUSE
θ value	4.40402e-47 (rank : 28)	NC score	0.943932 (rank : 29)
Query Neighborhood Hits	54	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBX19_MOUSE
θ value	9.81109e-47 (rank : 29)	NC score	0.953888 (rank : 25)
Query Neighborhood Hits	54	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

EOMES_HUMAN
θ value	9.50281e-42 (rank : 30)	NC score	0.942362 (rank : 30)
Query Neighborhood Hits	54	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

EOMES_MOUSE
θ value	9.50281e-42 (rank : 31)	NC score	0.940913 (rank : 31)
Query Neighborhood Hits	54	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

CAC1A_MOUSE
θ value	0.279714 (rank : 32)	NC score	0.010853 (rank : 36)
Query Neighborhood Hits	54	Target Neighborhood Hits	267	Shared Neighborhood Hits	5
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

K1802_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.005393 (rank : 44)
Query Neighborhood Hits	54	Target Neighborhood Hits	1378	Shared Neighborhood Hits	10
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ANR47_HUMAN
θ value	0.813845 (rank : 34)	NC score	0.006223 (rank : 43)
Query Neighborhood Hits	54	Target Neighborhood Hits	369	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

CBL_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.009766 (rank : 38)
Query Neighborhood Hits	54	Target Neighborhood Hits	426	Shared Neighborhood Hits	10
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CAC1A_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.008722 (rank : 40)
Query Neighborhood Hits	54	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

3BP1_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.005229 (rank : 45)
Query Neighborhood Hits	54	Target Neighborhood Hits	238	Shared Neighborhood Hits	5
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GGN_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.013514 (rank : 34)
Query Neighborhood Hits	54	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

DMRTD_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.008406 (rank : 41)
Query Neighborhood Hits	54	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

NU214_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.007633 (rank : 42)
Query Neighborhood Hits	54	Target Neighborhood Hits	657	Shared Neighborhood Hits	6
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUFP1_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.012272 (rank : 35)
Query Neighborhood Hits	54	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

RAI1_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.010672 (rank : 37)
Query Neighborhood Hits	54	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CCD95_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.017591 (rank : 32)
Query Neighborhood Hits	54	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

RX_HUMAN
θ value	5.27518 (rank : 44)	NC score	-0.000208 (rank : 51)
Query Neighborhood Hits	54	Target Neighborhood Hits	423	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SFR17_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.009587 (rank : 39)
Query Neighborhood Hits	54	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

EGR1_HUMAN
θ value	6.88961 (rank : 46)	NC score	-0.003884 (rank : 53)
Query Neighborhood Hits	54	Target Neighborhood Hits	788	Shared Neighborhood Hits	3
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

FGD2_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.001333 (rank : 49)
Query Neighborhood Hits	54	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

SCAP_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.003337 (rank : 46)
Query Neighborhood Hits	54	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

ALEX_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.014943 (rank : 33)
Query Neighborhood Hits	54	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

DYN2_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.002304 (rank : 47)
Query Neighborhood Hits	54	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

FMNL_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.001793 (rank : 48)
Query Neighborhood Hits	54	Target Neighborhood Hits	529	Shared Neighborhood Hits	7
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

OTX1_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.001053 (rank : 50)
Query Neighborhood Hits	54	Target Neighborhood Hits	372	Shared Neighborhood Hits	4
SwissProt Accessions	P80205	Gene names	Otx1, Otx-1
Domain Architecture
Description	Homeobox protein OTX1.

TESK1_HUMAN
θ value	8.99809 (rank : 53)	NC score	-0.003706 (rank : 52)
Query Neighborhood Hits	54	Target Neighborhood Hits	864	Shared Neighborhood Hits	4
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TESK1_MOUSE
θ value	8.99809 (rank : 54)	NC score	-0.004171 (rank : 54)
Query Neighborhood Hits	54	Target Neighborhood Hits	862	Shared Neighborhood Hits	4
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

Hits sorted by NC score

TBX6_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX6_HUMAN
NC score	0.996448 (rank : 2)	θ value	7.49059e-172 (rank : 2)
Query Neighborhood Hits	54	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX20_MOUSE
NC score	0.982365 (rank : 3)	θ value	1.23536e-57 (rank : 13)
Query Neighborhood Hits	54	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

TBX1_HUMAN
NC score	0.975732 (rank : 4)	θ value	1.51013e-55 (rank : 14)
Query Neighborhood Hits	54	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX1_MOUSE
NC score	0.975486 (rank : 5)	θ value	5.37103e-53 (rank : 19)
Query Neighborhood Hits	54	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX10_HUMAN
NC score	0.973618 (rank : 6)	θ value	7.49467e-55 (rank : 15)
Query Neighborhood Hits	54	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX10_MOUSE
NC score	0.973003 (rank : 7)	θ value	5.37103e-53 (rank : 18)
Query Neighborhood Hits	54	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX5_HUMAN
NC score	0.970134 (rank : 8)	θ value	1.41016e-61 (rank : 5)
Query Neighborhood Hits	54	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX22_HUMAN
NC score	0.969747 (rank : 9)	θ value	1.19655e-52 (rank : 20)
Query Neighborhood Hits	54	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX5_MOUSE
NC score	0.969488 (rank : 10)	θ value	1.41016e-61 (rank : 6)
Query Neighborhood Hits	54	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX4_HUMAN
NC score	0.969245 (rank : 11)	θ value	1.84173e-61 (rank : 8)
Query Neighborhood Hits	54	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX22_MOUSE
NC score	0.969090 (rank : 12)	θ value	1.19655e-52 (rank : 21)
Query Neighborhood Hits	54	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX4_MOUSE
NC score	0.968962 (rank : 13)	θ value	3.71096e-62 (rank : 4)
Query Neighborhood Hits	54	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX18_MOUSE
NC score	0.966203 (rank : 14)	θ value	1.7238e-59 (rank : 11)
Query Neighborhood Hits	54	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX2_MOUSE
NC score	0.964841 (rank : 15)	θ value	1.84173e-61 (rank : 7)
Query Neighborhood Hits	54	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX15_MOUSE
NC score	0.964529 (rank : 16)	θ value	2.25136e-59 (rank : 12)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

TBX15_HUMAN
NC score	0.964474 (rank : 17)	θ value	2.65945e-60 (rank : 9)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

TBX18_HUMAN
NC score	0.962406 (rank : 18)	θ value	5.92465e-60 (rank : 10)
Query Neighborhood Hits	54	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX3_MOUSE
NC score	0.961390 (rank : 19)	θ value	1.2784e-54 (rank : 17)
Query Neighborhood Hits	54	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX2_HUMAN
NC score	0.959638 (rank : 20)	θ value	3.71096e-62 (rank : 3)
Query Neighborhood Hits	54	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

BRAC_MOUSE
NC score	0.958820 (rank : 21)	θ value	5.55816e-50 (rank : 23)
Query Neighborhood Hits	54	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX19_HUMAN
NC score	0.957736 (rank : 22)	θ value	1.15895e-47 (rank : 25)
Query Neighborhood Hits	54	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

BRAC_HUMAN
NC score	0.957360 (rank : 23)	θ value	9.48078e-50 (rank : 24)
Query Neighborhood Hits	54	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX3_HUMAN
NC score	0.955743 (rank : 24)	θ value	9.78833e-55 (rank : 16)
Query Neighborhood Hits	54	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX19_MOUSE
NC score	0.953888 (rank : 25)	θ value	9.81109e-47 (rank : 29)
Query Neighborhood Hits	54	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX21_MOUSE
NC score	0.951315 (rank : 26)	θ value	1.97686e-47 (rank : 26)
Query Neighborhood Hits	54	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX21_HUMAN
NC score	0.948422 (rank : 27)	θ value	8.57503e-51 (rank : 22)
Query Neighborhood Hits	54	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBR1_HUMAN
NC score	0.943970 (rank : 28)	θ value	4.40402e-47 (rank : 27)
Query Neighborhood Hits	54	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_MOUSE
NC score	0.943932 (rank : 29)	θ value	4.40402e-47 (rank : 28)
Query Neighborhood Hits	54	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

EOMES_HUMAN
NC score	0.942362 (rank : 30)	θ value	9.50281e-42 (rank : 30)
Query Neighborhood Hits	54	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

EOMES_MOUSE
NC score	0.940913 (rank : 31)	θ value	9.50281e-42 (rank : 31)
Query Neighborhood Hits	54	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

CCD95_HUMAN
NC score	0.017591 (rank : 32)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	54	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

ALEX_HUMAN
NC score	0.014943 (rank : 33)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	54	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

GGN_HUMAN
NC score	0.013514 (rank : 34)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	54	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

NUFP1_HUMAN
NC score	0.012272 (rank : 35)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	54	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

CAC1A_MOUSE
NC score	0.010853 (rank : 36)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	54	Target Neighborhood Hits	267	Shared Neighborhood Hits	5
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

RAI1_HUMAN
NC score	0.010672 (rank : 37)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	54	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CBL_MOUSE
NC score	0.009766 (rank : 38)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	54	Target Neighborhood Hits	426	Shared Neighborhood Hits	10
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

SFR17_HUMAN
NC score	0.009587 (rank : 39)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	54	Target Neighborhood Hits	325	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

CAC1A_HUMAN
NC score	0.008722 (rank : 40)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	54	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

DMRTD_HUMAN
NC score	0.008406 (rank : 41)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	54	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

NU214_HUMAN
NC score	0.007633 (rank : 42)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	54	Target Neighborhood Hits	657	Shared Neighborhood Hits	6
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

ANR47_HUMAN
NC score	0.006223 (rank : 43)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	54	Target Neighborhood Hits	369	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

K1802_HUMAN
NC score	0.005393 (rank : 44)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	54	Target Neighborhood Hits	1378	Shared Neighborhood Hits	10
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

3BP1_MOUSE
NC score	0.005229 (rank : 45)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	54	Target Neighborhood Hits	238	Shared Neighborhood Hits	5
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

SCAP_HUMAN
NC score	0.003337 (rank : 46)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	54	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

DYN2_HUMAN
NC score	0.002304 (rank : 47)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	54	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

FMNL_HUMAN
NC score	0.001793 (rank : 48)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	54	Target Neighborhood Hits	529	Shared Neighborhood Hits	7
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FGD2_HUMAN
NC score	0.001333 (rank : 49)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	54	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

OTX1_MOUSE
NC score	0.001053 (rank : 50)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	54	Target Neighborhood Hits	372	Shared Neighborhood Hits	4
SwissProt Accessions	P80205	Gene names	Otx1, Otx-1
Domain Architecture
Description	Homeobox protein OTX1.

RX_HUMAN
NC score	-0.000208 (rank : 51)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	54	Target Neighborhood Hits	423	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

TESK1_HUMAN
NC score	-0.003706 (rank : 52)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	54	Target Neighborhood Hits	864	Shared Neighborhood Hits	4
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

EGR1_HUMAN
NC score	-0.003884 (rank : 53)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	54	Target Neighborhood Hits	788	Shared Neighborhood Hits	3
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

TESK1_MOUSE
NC score	-0.004171 (rank : 54)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	54	Target Neighborhood Hits	862	Shared Neighborhood Hits	4
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).