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Network neighborhood for query Sequence : TBR1_HUMAN

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TBR1_HUMAN
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TBR1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_MOUSE
θ value	0 (rank : 2)	NC score	0.999692 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	46
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

EOMES_MOUSE
θ value	1.86219e-138 (rank : 3)	NC score	0.985435 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

EOMES_HUMAN
θ value	2.51683e-135 (rank : 4)	NC score	0.986056 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	32
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

TBX21_HUMAN
θ value	2.72669e-89 (rank : 5)	NC score	0.966074 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	146	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX21_MOUSE
θ value	3.0147e-88 (rank : 6)	NC score	0.970149 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX5_HUMAN
θ value	3.2585e-50 (rank : 7)	NC score	0.939718 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
θ value	3.2585e-50 (rank : 8)	NC score	0.938988 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

BRAC_MOUSE
θ value	8.02596e-49 (rank : 9)	NC score	0.940769 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX4_HUMAN
θ value	1.788e-48 (rank : 10)	NC score	0.937535 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX4_MOUSE
θ value	1.788e-48 (rank : 11)	NC score	0.936531 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

BRAC_HUMAN
θ value	3.04986e-48 (rank : 12)	NC score	0.938963 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX19_HUMAN
θ value	3.04986e-48 (rank : 13)	NC score	0.941468 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX19_MOUSE
θ value	5.20228e-48 (rank : 14)	NC score	0.938708 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX6_HUMAN
θ value	1.51363e-47 (rank : 15)	NC score	0.947054 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX6_MOUSE
θ value	4.40402e-47 (rank : 16)	NC score	0.943970 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX2_HUMAN
θ value	1.28137e-46 (rank : 17)	NC score	0.925543 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX2_MOUSE
θ value	1.28137e-46 (rank : 18)	NC score	0.930787 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX18_HUMAN
θ value	1.85029e-45 (rank : 19)	NC score	0.926366 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX18_MOUSE
θ value	1.85029e-45 (rank : 20)	NC score	0.929176 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX3_HUMAN
θ value	1.85029e-45 (rank : 21)	NC score	0.923934 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX3_MOUSE
θ value	1.85029e-45 (rank : 22)	NC score	0.929582 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX15_HUMAN
θ value	3.48949e-44 (rank : 23)	NC score	0.925919 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

TBX15_MOUSE
θ value	3.48949e-44 (rank : 24)	NC score	0.926178 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

TBX22_MOUSE
θ value	3.48949e-44 (rank : 25)	NC score	0.936915 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX10_HUMAN
θ value	4.55743e-44 (rank : 26)	NC score	0.939798 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX1_MOUSE
θ value	4.55743e-44 (rank : 27)	NC score	0.942285 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX1_HUMAN
θ value	1.73182e-43 (rank : 28)	NC score	0.941271 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX22_HUMAN
θ value	3.85808e-43 (rank : 29)	NC score	0.936304 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX10_MOUSE
θ value	6.58091e-43 (rank : 30)	NC score	0.940009 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX20_MOUSE
θ value	1.2411e-41 (rank : 31)	NC score	0.947166 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

SOX30_MOUSE
θ value	0.00390308 (rank : 32)	NC score	0.044071 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	374	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

ATN1_HUMAN
θ value	0.125558 (rank : 33)	NC score	0.031102 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	676	Shared Neighborhood Hits	14
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ARRD1_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.033948 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

BBX_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.017162 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

RUNX3_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.024185 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

ATX2L_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.027324 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

SOX30_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.026853 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

ATX2L_MOUSE
θ value	1.38821 (rank : 39)	NC score	0.025905 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CRSP2_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.031936 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	380	Shared Neighborhood Hits	8
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

EVI2B_MOUSE
θ value	2.36792 (rank : 41)	NC score	0.023776 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

GPS2_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.025550 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	459	Shared Neighborhood Hits	10
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

ARI1A_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.009945 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	787	Shared Neighborhood Hits	12
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BCL9_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.009999 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	770	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

KISS1_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.015138 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q6Y4S4, Q68Y93, Q80XF6	Gene names	Kiss1
Domain Architecture	No domain graphic available
Description	Metastasis-suppressor KiSS-1 precursor (Kisspeptin-1) [Contains: Metastin (Kisspeptin-52); Kisspeptin-10 (Metastin45-54)].

RASF7_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.014320 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

ADA15_HUMAN
θ value	8.99809 (rank : 47)	NC score	-0.000060 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	288	Shared Neighborhood Hits	2
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ALEX_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.014145 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

FLCN_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.006446 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8QZS3, Q3U4U8, Q3UFZ1, Q5SWZ2, Q5SX01, Q5SX02, Q8CAC0	Gene names	Flcn
Domain Architecture	No domain graphic available
Description	Folliculin.

TFG_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.016964 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

US6NL_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.006681 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

Hits sorted by NC score

TBR1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_MOUSE
NC score	0.999692 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	46
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

EOMES_HUMAN
NC score	0.986056 (rank : 3)	θ value	2.51683e-135 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	32
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

EOMES_MOUSE
NC score	0.985435 (rank : 4)	θ value	1.86219e-138 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

TBX21_MOUSE
NC score	0.970149 (rank : 5)	θ value	3.0147e-88 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX21_HUMAN
NC score	0.966074 (rank : 6)	θ value	2.72669e-89 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	146	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX20_MOUSE
NC score	0.947166 (rank : 7)	θ value	1.2411e-41 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

TBX6_HUMAN
NC score	0.947054 (rank : 8)	θ value	1.51363e-47 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX6_MOUSE
NC score	0.943970 (rank : 9)	θ value	4.40402e-47 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX1_MOUSE
NC score	0.942285 (rank : 10)	θ value	4.55743e-44 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX19_HUMAN
NC score	0.941468 (rank : 11)	θ value	3.04986e-48 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX1_HUMAN
NC score	0.941271 (rank : 12)	θ value	1.73182e-43 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

BRAC_MOUSE
NC score	0.940769 (rank : 13)	θ value	8.02596e-49 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX10_MOUSE
NC score	0.940009 (rank : 14)	θ value	6.58091e-43 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX10_HUMAN
NC score	0.939798 (rank : 15)	θ value	4.55743e-44 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX5_HUMAN
NC score	0.939718 (rank : 16)	θ value	3.2585e-50 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
NC score	0.938988 (rank : 17)	θ value	3.2585e-50 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

BRAC_HUMAN
NC score	0.938963 (rank : 18)	θ value	3.04986e-48 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX19_MOUSE
NC score	0.938708 (rank : 19)	θ value	5.20228e-48 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX4_HUMAN
NC score	0.937535 (rank : 20)	θ value	1.788e-48 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX22_MOUSE
NC score	0.936915 (rank : 21)	θ value	3.48949e-44 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX4_MOUSE
NC score	0.936531 (rank : 22)	θ value	1.788e-48 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX22_HUMAN
NC score	0.936304 (rank : 23)	θ value	3.85808e-43 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX2_MOUSE
NC score	0.930787 (rank : 24)	θ value	1.28137e-46 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX3_MOUSE
NC score	0.929582 (rank : 25)	θ value	1.85029e-45 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX18_MOUSE
NC score	0.929176 (rank : 26)	θ value	1.85029e-45 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX18_HUMAN
NC score	0.926366 (rank : 27)	θ value	1.85029e-45 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX15_MOUSE
NC score	0.926178 (rank : 28)	θ value	3.48949e-44 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

TBX15_HUMAN
NC score	0.925919 (rank : 29)	θ value	3.48949e-44 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	32
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

TBX2_HUMAN
NC score	0.925543 (rank : 30)	θ value	1.28137e-46 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX3_HUMAN
NC score	0.923934 (rank : 31)	θ value	1.85029e-45 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

SOX30_MOUSE
NC score	0.044071 (rank : 32)	θ value	0.00390308 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	374	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

ARRD1_MOUSE
NC score	0.033948 (rank : 33)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

CRSP2_HUMAN
NC score	0.031936 (rank : 34)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	380	Shared Neighborhood Hits	8
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

ATN1_HUMAN
NC score	0.031102 (rank : 35)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	676	Shared Neighborhood Hits	14
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX2L_HUMAN
NC score	0.027324 (rank : 36)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

SOX30_HUMAN
NC score	0.026853 (rank : 37)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

ATX2L_MOUSE
NC score	0.025905 (rank : 38)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

GPS2_HUMAN
NC score	0.025550 (rank : 39)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	459	Shared Neighborhood Hits	10
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

RUNX3_HUMAN
NC score	0.024185 (rank : 40)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

EVI2B_MOUSE
NC score	0.023776 (rank : 41)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

BBX_HUMAN
NC score	0.017162 (rank : 42)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

TFG_HUMAN
NC score	0.016964 (rank : 43)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

KISS1_MOUSE
NC score	0.015138 (rank : 44)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q6Y4S4, Q68Y93, Q80XF6	Gene names	Kiss1
Domain Architecture	No domain graphic available
Description	Metastasis-suppressor KiSS-1 precursor (Kisspeptin-1) [Contains: Metastin (Kisspeptin-52); Kisspeptin-10 (Metastin45-54)].

RASF7_MOUSE
NC score	0.014320 (rank : 45)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

ALEX_HUMAN
NC score	0.014145 (rank : 46)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BCL9_MOUSE
NC score	0.009999 (rank : 47)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	770	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

ARI1A_HUMAN
NC score	0.009945 (rank : 48)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	787	Shared Neighborhood Hits	12
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

US6NL_HUMAN
NC score	0.006681 (rank : 49)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

FLCN_MOUSE
NC score	0.006446 (rank : 50)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8QZS3, Q3U4U8, Q3UFZ1, Q5SWZ2, Q5SX01, Q5SX02, Q8CAC0	Gene names	Flcn
Domain Architecture	No domain graphic available
Description	Folliculin.

ADA15_HUMAN
NC score	-0.000060 (rank : 51)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	288	Shared Neighborhood Hits	2
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).