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Network neighborhood for query Sequence : TBX2_MOUSE

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TBX2_MOUSE
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TBX2_HUMAN
θ value	0 (rank : 1)	NC score	0.990661 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	195	Shared Neighborhood Hits	59
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX3_MOUSE
θ value	7.28896e-151 (rank : 3)	NC score	0.988936 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	34
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX3_HUMAN
θ value	2.19465e-147 (rank : 4)	NC score	0.983041 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX4_MOUSE
θ value	6.98233e-69 (rank : 5)	NC score	0.961781 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX4_HUMAN
θ value	1.90147e-66 (rank : 6)	NC score	0.961410 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX5_HUMAN
θ value	2.74572e-65 (rank : 7)	NC score	0.961727 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX5_MOUSE
θ value	2.74572e-65 (rank : 8)	NC score	0.961105 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX20_MOUSE
θ value	3.58603e-65 (rank : 9)	NC score	0.975991 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

TBX6_HUMAN
θ value	1.27544e-62 (rank : 10)	NC score	0.968070 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX6_MOUSE
θ value	1.84173e-61 (rank : 11)	NC score	0.964841 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX1_MOUSE
θ value	3.14151e-61 (rank : 12)	NC score	0.969797 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX1_HUMAN
θ value	4.10295e-61 (rank : 13)	NC score	0.970127 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX10_MOUSE
θ value	1.19377e-60 (rank : 14)	NC score	0.966826 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX10_HUMAN
θ value	2.03627e-60 (rank : 15)	NC score	0.967140 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX18_HUMAN
θ value	3.47335e-60 (rank : 16)	NC score	0.949502 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX18_MOUSE
θ value	8.55514e-59 (rank : 17)	NC score	0.953126 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX15_HUMAN
θ value	6.77864e-56 (rank : 18)	NC score	0.949531 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

TBX15_MOUSE
θ value	2.57589e-55 (rank : 19)	NC score	0.949492 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

TBX22_MOUSE
θ value	4.54686e-52 (rank : 20)	NC score	0.956470 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX22_HUMAN
θ value	7.75577e-52 (rank : 21)	NC score	0.956878 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

BRAC_HUMAN
θ value	8.57503e-51 (rank : 22)	NC score	0.945258 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

BRAC_MOUSE
θ value	2.49495e-50 (rank : 23)	NC score	0.946376 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX21_HUMAN
θ value	6.7944e-48 (rank : 24)	NC score	0.934491 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBR1_HUMAN
θ value	1.28137e-46 (rank : 25)	NC score	0.930787 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_MOUSE
θ value	1.28137e-46 (rank : 26)	NC score	0.930777 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBX21_MOUSE
θ value	2.85459e-46 (rank : 27)	NC score	0.937346 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

EOMES_HUMAN
θ value	1.41672e-45 (rank : 28)	NC score	0.932001 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	57	Shared Neighborhood Hits	33
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

EOMES_MOUSE
θ value	9.18288e-45 (rank : 29)	NC score	0.930184 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	59	Shared Neighborhood Hits	32
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

TBX19_HUMAN
θ value	9.18288e-45 (rank : 30)	NC score	0.942909 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX19_MOUSE
θ value	9.18288e-45 (rank : 31)	NC score	0.939593 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

NFH_MOUSE
θ value	0.000121331 (rank : 32)	NC score	0.029525 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	2247	Shared Neighborhood Hits	47
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RGS3_MOUSE
θ value	0.0330416 (rank : 33)	NC score	0.015980 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	1621	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

IWS1_MOUSE
θ value	0.0736092 (rank : 34)	NC score	0.017850 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	1258	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SC5A3_MOUSE
θ value	0.125558 (rank : 35)	NC score	0.025993 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

TLX2_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.008341 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	O43763, Q9UQ48	Gene names	TLX2, HOX11L1, NCX
Domain Architecture
Description	T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein).

K1802_MOUSE
θ value	0.279714 (rank : 37)	NC score	0.010748 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	1596	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RBM6_HUMAN
θ value	0.279714 (rank : 38)	NC score	0.022672 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	221	Shared Neighborhood Hits	8
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

RP3A_MOUSE
θ value	0.365318 (rank : 39)	NC score	0.012975 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	510	Shared Neighborhood Hits	18
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

IF4G3_MOUSE
θ value	0.47712 (rank : 40)	NC score	0.021797 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	279	Shared Neighborhood Hits	16
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

APC_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.019363 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	603	Shared Neighborhood Hits	21
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

SPEG_MOUSE
θ value	0.62314 (rank : 42)	NC score	0.001180 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	1959	Shared Neighborhood Hits	36
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

GNAQ_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.010683 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P50148, O15108, Q13462, Q92471, Q9BZB9	Gene names	GNAQ, GAQ
Domain Architecture
Description	Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q).

GNAQ_MOUSE
θ value	0.813845 (rank : 44)	NC score	0.010674 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P21279, Q6PFF5	Gene names	Gnaq
Domain Architecture
Description	Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q).

PARG_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.018282 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

RGS3_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.016954 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	1375	Shared Neighborhood Hits	28
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CENG1_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.008128 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	544	Shared Neighborhood Hits	13
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

TTBK1_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.004532 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	1058	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

IGS21_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.016463 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

INVS_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.005858 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	609	Shared Neighborhood Hits	17
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

SC5A3_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.019190 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SRRM2_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.033906 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ABL1_HUMAN
θ value	2.36792 (rank : 53)	NC score	-0.002424 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	1220	Shared Neighborhood Hits	18
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ACINU_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.018035 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	712	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NACAM_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.012926 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	1866	Shared Neighborhood Hits	38
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PHC2_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.011885 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	388	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

TULP1_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.012431 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

CENG1_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.008408 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	531	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

ERBB3_MOUSE
θ value	3.0926 (rank : 59)	NC score	-0.000534 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	898	Shared Neighborhood Hits	11
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

IKBL_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.018312 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	196	Shared Neighborhood Hits	7
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

JIP3_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.004506 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	1039	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MICA1_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.007964 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	400	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

NFM_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.005716 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	1328	Shared Neighborhood Hits	28
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SEPT9_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.005218 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	706	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ZN683_HUMAN
θ value	3.0926 (rank : 65)	NC score	-0.003481 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	750	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZ20, Q5T141, Q5T146, Q5T147, Q5T149, Q8NEN4	Gene names	ZNF683
Domain Architecture	No domain graphic available
Description	Zinc finger protein 683.

ARI4A_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.008571 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	434	Shared Neighborhood Hits	10
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CTRO_MOUSE
θ value	4.03905 (rank : 67)	NC score	-0.004234 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	2344	Shared Neighborhood Hits	27
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DOT1L_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.014857 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	660	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

IGS21_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.014350 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

K0586_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.020619 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	311	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

LRRF1_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.008969 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	625	Shared Neighborhood Hits	11
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

OGFR_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.019111 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	1582	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RIMB1_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.008076 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	1479	Shared Neighborhood Hits	34
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SRBS1_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.011790 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	396	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CABIN_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.022497 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CCD45_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.003330 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	525	Shared Neighborhood Hits	10
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

GTSE1_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.019983 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	193	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

PI5PA_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.011062 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	749	Shared Neighborhood Hits	26
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

TXLNA_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.002841 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	982	Shared Neighborhood Hits	22
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

UST_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.014790 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUB6	Gene names	Ust
Domain Architecture	No domain graphic available
Description	Uronyl 2-sulfotransferase (EC 2.8.2.-).

AKAP2_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.005209 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	507	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

COA2_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.006303 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	184	Shared Neighborhood Hits	12
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

GP124_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.000052 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	423	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

NKTR_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.004896 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	417	Shared Neighborhood Hits	10
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PGCA_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.003531 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	643	Shared Neighborhood Hits	15
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

SPTB2_MOUSE
θ value	6.88961 (rank : 86)	NC score	-0.000294 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	770	Shared Neighborhood Hits	15
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

TACC3_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.004369 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	779	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

ZN398_HUMAN
θ value	6.88961 (rank : 88)	NC score	-0.004601 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	765	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TD17, Q8TD18, Q9P2K7, Q9UDV8	Gene names	ZNF398, KIAA1339, ZER6
Domain Architecture
Description	Zinc finger protein 398 (Zinc finger DNA-binding protein p52/p71).

BRE1B_HUMAN
θ value	8.99809 (rank : 89)	NC score	-0.000237 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	1040	Shared Neighborhood Hits	14
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CYTSA_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.000596 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	1138	Shared Neighborhood Hits	19
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

LPP_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.002189 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	775	Shared Neighborhood Hits	15
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

SRRM2_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.034063 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	1296	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SSPO_MOUSE
θ value	8.99809 (rank : 93)	NC score	-0.000154 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	800	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STX18_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.007295 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

TARA_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.008850 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	1626	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TR150_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.014086 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	468	Shared Neighborhood Hits	16
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ULK1_HUMAN
θ value	8.99809 (rank : 97)	NC score	-0.002724 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	1121	Shared Neighborhood Hits	18
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

Hits sorted by NC score

TBX2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX2_HUMAN
NC score	0.990661 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	195	Shared Neighborhood Hits	59
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TBX3_MOUSE
NC score	0.988936 (rank : 3)	θ value	7.28896e-151 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	34
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX3_HUMAN
NC score	0.983041 (rank : 4)	θ value	2.19465e-147 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

TBX20_MOUSE
NC score	0.975991 (rank : 5)	θ value	3.58603e-65 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES03, Q9ESX1	Gene names	Tbx20, Tbx12
Domain Architecture
Description	T-box transcription factor TBX20 (T-box protein 20).

TBX1_HUMAN
NC score	0.970127 (rank : 6)	θ value	4.10295e-61 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX1_MOUSE
NC score	0.969797 (rank : 7)	θ value	3.14151e-61 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	P70323, Q60706, Q99MP0, Q99P22	Gene names	Tbx1
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

TBX6_HUMAN
NC score	0.968070 (rank : 8)	θ value	1.27544e-62 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX10_HUMAN
NC score	0.967140 (rank : 9)	θ value	2.03627e-60 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	O75333, Q86XS3	Gene names	TBX10, TBX7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10).

TBX10_MOUSE
NC score	0.966826 (rank : 10)	θ value	1.19377e-60 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

TBX6_MOUSE
NC score	0.964841 (rank : 11)	θ value	1.84173e-61 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	P70327	Gene names	Tbx6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TBX4_MOUSE
NC score	0.961781 (rank : 12)	θ value	6.98233e-69 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	P70325, Q8R5F6	Gene names	Tbx4
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX5_HUMAN
NC score	0.961727 (rank : 13)	θ value	2.74572e-65 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q99593, O15301, Q9Y4I2	Gene names	TBX5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX4_HUMAN
NC score	0.961410 (rank : 14)	θ value	1.90147e-66 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TBX5_MOUSE
NC score	0.961105 (rank : 15)	θ value	2.74572e-65 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P70326, Q9R003	Gene names	Tbx5
Domain Architecture
Description	T-box transcription factor TBX5 (T-box protein 5).

TBX22_HUMAN
NC score	0.956878 (rank : 16)	θ value	7.75577e-52 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX22_MOUSE
NC score	0.956470 (rank : 17)	θ value	4.54686e-52 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K402	Gene names	Tbx22
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX22 (T-box protein 22).

TBX18_MOUSE
NC score	0.953126 (rank : 18)	θ value	8.55514e-59 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX15_HUMAN
NC score	0.949531 (rank : 19)	θ value	6.77864e-56 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

TBX18_HUMAN
NC score	0.949502 (rank : 20)	θ value	3.47335e-60 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TBX15_MOUSE
NC score	0.949492 (rank : 21)	θ value	2.57589e-55 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

BRAC_MOUSE
NC score	0.946376 (rank : 22)	θ value	2.49495e-50 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	P20293	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

BRAC_HUMAN
NC score	0.945258 (rank : 23)	θ value	8.57503e-51 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O15178	Gene names	T
Domain Architecture
Description	Brachyury protein (T protein).

TBX19_HUMAN
NC score	0.942909 (rank : 24)	θ value	9.18288e-45 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	O60806	Gene names	TBX19, TPIT
Domain Architecture
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX19_MOUSE
NC score	0.939593 (rank : 25)	θ value	9.18288e-45 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TBX21_MOUSE
NC score	0.937346 (rank : 26)	θ value	2.85459e-46 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	116	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX21_HUMAN
NC score	0.934491 (rank : 27)	θ value	6.7944e-48 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

EOMES_HUMAN
NC score	0.932001 (rank : 28)	θ value	1.41672e-45 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	57	Shared Neighborhood Hits	33
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

TBR1_HUMAN
NC score	0.930787 (rank : 29)	θ value	1.28137e-46 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_MOUSE
NC score	0.930777 (rank : 30)	θ value	1.28137e-46 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

EOMES_MOUSE
NC score	0.930184 (rank : 31)	θ value	9.18288e-45 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	59	Shared Neighborhood Hits	32
SwissProt Accessions	O54839, Q9QYG7	Gene names	Eomes, Tbr2
Domain Architecture
Description	Eomesodermin homolog.

SRRM2_HUMAN
NC score	0.034063 (rank : 32)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	1296	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.033906 (rank : 33)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NFH_MOUSE
NC score	0.029525 (rank : 34)	θ value	0.000121331 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	2247	Shared Neighborhood Hits	47
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SC5A3_MOUSE
NC score	0.025993 (rank : 35)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

RBM6_HUMAN
NC score	0.022672 (rank : 36)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	221	Shared Neighborhood Hits	8
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

CABIN_HUMAN
NC score	0.022497 (rank : 37)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

IF4G3_MOUSE
NC score	0.021797 (rank : 38)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	279	Shared Neighborhood Hits	16
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K0586_HUMAN
NC score	0.020619 (rank : 39)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	311	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

GTSE1_HUMAN
NC score	0.019983 (rank : 40)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	193	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

APC_HUMAN
NC score	0.019363 (rank : 41)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	603	Shared Neighborhood Hits	21
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

SC5A3_HUMAN
NC score	0.019190 (rank : 42)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

OGFR_HUMAN
NC score	0.019111 (rank : 43)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	1582	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

IKBL_MOUSE
NC score	0.018312 (rank : 44)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	196	Shared Neighborhood Hits	7
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

PARG_HUMAN
NC score	0.018282 (rank : 45)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

ACINU_MOUSE
NC score	0.018035 (rank : 46)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	712	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

IWS1_MOUSE
NC score	0.017850 (rank : 47)	θ value	0.0736092 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	1258	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RGS3_HUMAN
NC score	0.016954 (rank : 48)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	1375	Shared Neighborhood Hits	28
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

IGS21_MOUSE
NC score	0.016463 (rank : 49)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

RGS3_MOUSE
NC score	0.015980 (rank : 50)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	1621	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DOT1L_HUMAN
NC score	0.014857 (rank : 51)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	660	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

UST_MOUSE
NC score	0.014790 (rank : 52)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUB6	Gene names	Ust
Domain Architecture	No domain graphic available
Description	Uronyl 2-sulfotransferase (EC 2.8.2.-).

IGS21_HUMAN
NC score	0.014350 (rank : 53)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

TR150_MOUSE
NC score	0.014086 (rank : 54)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	468	Shared Neighborhood Hits	16
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

RP3A_MOUSE
NC score	0.012975 (rank : 55)	θ value	0.365318 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	510	Shared Neighborhood Hits	18
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

NACAM_MOUSE
NC score	0.012926 (rank : 56)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	1866	Shared Neighborhood Hits	38
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TULP1_MOUSE
NC score	0.012431 (rank : 57)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

PHC2_HUMAN
NC score	0.011885 (rank : 58)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	388	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

SRBS1_HUMAN
NC score	0.011790 (rank : 59)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	396	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PI5PA_HUMAN
NC score	0.011062 (rank : 60)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	749	Shared Neighborhood Hits	26
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

K1802_MOUSE
NC score	0.010748 (rank : 61)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	1596	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

GNAQ_HUMAN
NC score	0.010683 (rank : 62)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P50148, O15108, Q13462, Q92471, Q9BZB9	Gene names	GNAQ, GAQ
Domain Architecture
Description	Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q).

GNAQ_MOUSE
NC score	0.010674 (rank : 63)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P21279, Q6PFF5	Gene names	Gnaq
Domain Architecture
Description	Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q).

LRRF1_HUMAN
NC score	0.008969 (rank : 64)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	625	Shared Neighborhood Hits	11
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

TARA_HUMAN
NC score	0.008850 (rank : 65)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	1626	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ARI4A_HUMAN
NC score	0.008571 (rank : 66)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	434	Shared Neighborhood Hits	10
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CENG1_MOUSE
NC score	0.008408 (rank : 67)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	531	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

TLX2_HUMAN
NC score	0.008341 (rank : 68)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	O43763, Q9UQ48	Gene names	TLX2, HOX11L1, NCX
Domain Architecture
Description	T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein).

CENG1_HUMAN
NC score	0.008128 (rank : 69)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	544	Shared Neighborhood Hits	13
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

RIMB1_HUMAN
NC score	0.008076 (rank : 70)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	1479	Shared Neighborhood Hits	34
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MICA1_MOUSE
NC score	0.007964 (rank : 71)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	400	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

STX18_HUMAN
NC score	0.007295 (rank : 72)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

COA2_HUMAN
NC score	0.006303 (rank : 73)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	184	Shared Neighborhood Hits	12
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

INVS_MOUSE
NC score	0.005858 (rank : 74)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	609	Shared Neighborhood Hits	17
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

NFM_HUMAN
NC score	0.005716 (rank : 75)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	1328	Shared Neighborhood Hits	28
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SEPT9_HUMAN
NC score	0.005218 (rank : 76)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	706	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

AKAP2_HUMAN
NC score	0.005209 (rank : 77)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	507	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

NKTR_MOUSE
NC score	0.004896 (rank : 78)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	417	Shared Neighborhood Hits	10
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TTBK1_HUMAN
NC score	0.004532 (rank : 79)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	1058	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

JIP3_HUMAN
NC score	0.004506 (rank : 80)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	1039	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

TACC3_HUMAN
NC score	0.004369 (rank : 81)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	779	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

PGCA_MOUSE
NC score	0.003531 (rank : 82)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	643	Shared Neighborhood Hits	15
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

CCD45_HUMAN
NC score	0.003330 (rank : 83)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	525	Shared Neighborhood Hits	10
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

TXLNA_HUMAN
NC score	0.002841 (rank : 84)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	982	Shared Neighborhood Hits	22
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

LPP_HUMAN
NC score	0.002189 (rank : 85)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	775	Shared Neighborhood Hits	15
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

SPEG_MOUSE
NC score	0.001180 (rank : 86)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	1959	Shared Neighborhood Hits	36
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CYTSA_HUMAN
NC score	0.000596 (rank : 87)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	1138	Shared Neighborhood Hits	19
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

GP124_MOUSE
NC score	0.000052 (rank : 88)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	423	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

SSPO_MOUSE
NC score	-0.000154 (rank : 89)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	800	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

BRE1B_HUMAN
NC score	-0.000237 (rank : 90)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	1040	Shared Neighborhood Hits	14
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

SPTB2_MOUSE
NC score	-0.000294 (rank : 91)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	770	Shared Neighborhood Hits	15
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

ERBB3_MOUSE
NC score	-0.000534 (rank : 92)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	898	Shared Neighborhood Hits	11
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ABL1_HUMAN
NC score	-0.002424 (rank : 93)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	1220	Shared Neighborhood Hits	18
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ULK1_HUMAN
NC score	-0.002724 (rank : 94)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	1121	Shared Neighborhood Hits	18
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZN683_HUMAN
NC score	-0.003481 (rank : 95)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	750	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZ20, Q5T141, Q5T146, Q5T147, Q5T149, Q8NEN4	Gene names	ZNF683
Domain Architecture	No domain graphic available
Description	Zinc finger protein 683.

CTRO_MOUSE
NC score	-0.004234 (rank : 96)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	2344	Shared Neighborhood Hits	27
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ZN398_HUMAN
NC score	-0.004601 (rank : 97)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	765	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TD17, Q8TD18, Q9P2K7, Q9UDV8	Gene names	ZNF398, KIAA1339, ZER6
Domain Architecture
Description	Zinc finger protein 398 (Zinc finger DNA-binding protein p52/p71).