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Network neighborhood for query Sequence : COA2_HUMAN

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COA2_HUMAN
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COA1_HUMAN
θ value	0 (rank : 1)	NC score	0.968167 (rank : 2)
Query Neighborhood Hits	184	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

COA2_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	184	Target Neighborhood Hits	184	Shared Neighborhood Hits	184
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

PCCA_HUMAN
θ value	2.10721e-57 (rank : 3)	NC score	0.790805 (rank : 3)
Query Neighborhood Hits	184	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	P05165, Q15979	Gene names	PCCA
Domain Architecture
Description	Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).

PCCA_MOUSE
θ value	2.32979e-56 (rank : 4)	NC score	0.790193 (rank : 4)
Query Neighborhood Hits	184	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZA3, Q80VU5, Q922N3	Gene names	Pcca
Domain Architecture	No domain graphic available
Description	Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).

MCCA_HUMAN
θ value	1.51013e-55 (rank : 5)	NC score	0.785866 (rank : 6)
Query Neighborhood Hits	184	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RQ3, Q59ES4, Q9H959, Q9NS97	Gene names	MCCC1, MCCA
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

MCCA_MOUSE
θ value	6.34462e-54 (rank : 6)	NC score	0.786731 (rank : 5)
Query Neighborhood Hits	184	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MR8, Q3TGU0, Q9D8R2	Gene names	Mccc1, Mcca
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

PYC_MOUSE
θ value	9.48078e-50 (rank : 7)	NC score	0.760277 (rank : 7)
Query Neighborhood Hits	184	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q05920	Gene names	Pc, Pcx
Domain Architecture
Description	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).

PYC_HUMAN
θ value	2.1121e-49 (rank : 8)	NC score	0.759553 (rank : 8)
Query Neighborhood Hits	184	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	P11498, Q16705	Gene names	PC
Domain Architecture
Description	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).

PCCB_MOUSE
θ value	7.58209e-15 (rank : 9)	NC score	0.363728 (rank : 9)
Query Neighborhood Hits	184	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MN9	Gene names	Pccb
Domain Architecture	No domain graphic available
Description	Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).

PCCB_HUMAN
θ value	2.88119e-14 (rank : 10)	NC score	0.358422 (rank : 10)
Query Neighborhood Hits	184	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P05166, Q16813	Gene names	PCCB
Domain Architecture
Description	Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).

PYR1_HUMAN
θ value	7.34386e-10 (rank : 11)	NC score	0.351412 (rank : 11)
Query Neighborhood Hits	184	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

CPSM_HUMAN
θ value	1.69304e-06 (rank : 12)	NC score	0.344931 (rank : 13)
Query Neighborhood Hits	184	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	P31327, O43774, Q7Z5I5	Gene names	CPS1
Domain Architecture
Description	Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).

CPSM_MOUSE
θ value	1.43324e-05 (rank : 13)	NC score	0.344981 (rank : 12)
Query Neighborhood Hits	184	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C196, Q6NX75	Gene names	Cps1
Domain Architecture	No domain graphic available
Description	Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).

MCCC2_HUMAN
θ value	9.29e-05 (rank : 14)	NC score	0.249906 (rank : 14)
Query Neighborhood Hits	184	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCC0, Q96C27, Q9Y4L7	Gene names	MCCC2, MCCB
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.4) (3-Methylcrotonyl-CoA carboxylase 2) (MCCase subunit beta) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) (3- Methylcrotonyl-CoA carboxylase non-biotin-containing subunit).

SYN2_MOUSE
θ value	0.000461057 (rank : 15)	NC score	0.082046 (rank : 15)
Query Neighborhood Hits	184	Target Neighborhood Hits	183	Shared Neighborhood Hits	25
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

SYN2_HUMAN
θ value	0.000602161 (rank : 16)	NC score	0.078893 (rank : 16)
Query Neighborhood Hits	184	Target Neighborhood Hits	213	Shared Neighborhood Hits	19
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

MEGF9_MOUSE
θ value	0.0113563 (rank : 17)	NC score	0.035040 (rank : 73)
Query Neighborhood Hits	184	Target Neighborhood Hits	896	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PININ_MOUSE
θ value	0.0113563 (rank : 18)	NC score	0.057596 (rank : 33)
Query Neighborhood Hits	184	Target Neighborhood Hits	777	Shared Neighborhood Hits	25
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SH3K1_HUMAN
θ value	0.0252991 (rank : 19)	NC score	0.042663 (rank : 53)
Query Neighborhood Hits	184	Target Neighborhood Hits	341	Shared Neighborhood Hits	12
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

NPBL_MOUSE
θ value	0.0330416 (rank : 20)	NC score	0.073050 (rank : 18)
Query Neighborhood Hits	184	Target Neighborhood Hits	1041	Shared Neighborhood Hits	66
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

WASIP_MOUSE
θ value	0.0330416 (rank : 21)	NC score	0.076758 (rank : 17)
Query Neighborhood Hits	184	Target Neighborhood Hits	392	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

XRCC1_MOUSE
θ value	0.0330416 (rank : 22)	NC score	0.057658 (rank : 32)
Query Neighborhood Hits	184	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

AFF1_MOUSE
θ value	0.0431538 (rank : 23)	NC score	0.064092 (rank : 26)
Query Neighborhood Hits	184	Target Neighborhood Hits	351	Shared Neighborhood Hits	28
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

PO6F2_MOUSE
θ value	0.0431538 (rank : 24)	NC score	0.028019 (rank : 96)
Query Neighborhood Hits	184	Target Neighborhood Hits	639	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

SH3K1_MOUSE
θ value	0.0431538 (rank : 25)	NC score	0.041095 (rank : 58)
Query Neighborhood Hits	184	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

KCNK4_HUMAN
θ value	0.0563607 (rank : 26)	NC score	0.030386 (rank : 87)
Query Neighborhood Hits	184	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

SRRM2_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.070718 (rank : 21)
Query Neighborhood Hits	184	Target Neighborhood Hits	1296	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MYCB2_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.039051 (rank : 60)
Query Neighborhood Hits	184	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PININ_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.048962 (rank : 41)
Query Neighborhood Hits	184	Target Neighborhood Hits	753	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PKHA6_HUMAN
θ value	0.0736092 (rank : 30)	NC score	0.035718 (rank : 70)
Query Neighborhood Hits	184	Target Neighborhood Hits	556	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

WASIP_HUMAN
θ value	0.0736092 (rank : 31)	NC score	0.072032 (rank : 19)
Query Neighborhood Hits	184	Target Neighborhood Hits	458	Shared Neighborhood Hits	33
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ELOA3_HUMAN
θ value	0.0961366 (rank : 32)	NC score	0.047363 (rank : 44)
Query Neighborhood Hits	184	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

NOLC1_HUMAN
θ value	0.0961366 (rank : 33)	NC score	0.059069 (rank : 31)
Query Neighborhood Hits	184	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NIPBL_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.064686 (rank : 25)
Query Neighborhood Hits	184	Target Neighborhood Hits	1311	Shared Neighborhood Hits	67
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PCLO_HUMAN
θ value	0.125558 (rank : 35)	NC score	0.045396 (rank : 51)
Query Neighborhood Hits	184	Target Neighborhood Hits	2046	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRG4_MOUSE
θ value	0.125558 (rank : 36)	NC score	0.042326 (rank : 54)
Query Neighborhood Hits	184	Target Neighborhood Hits	624	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRRM2_MOUSE
θ value	0.125558 (rank : 37)	NC score	0.071301 (rank : 20)
Query Neighborhood Hits	184	Target Neighborhood Hits	1470	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

UBP31_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.032601 (rank : 83)
Query Neighborhood Hits	184	Target Neighborhood Hits	293	Shared Neighborhood Hits	26
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

FOXGB_MOUSE
θ value	0.163984 (rank : 39)	NC score	0.016226 (rank : 127)
Query Neighborhood Hits	184	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	Q60987, Q80VP3	Gene names	Foxg1b, Fkhl1, Foxg1, Hfhbf1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1).

CJ086_HUMAN
θ value	0.21417 (rank : 40)	NC score	0.064889 (rank : 24)
Query Neighborhood Hits	184	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NXX6, Q5SQQ5, Q6P673, Q8WY66, Q9BS90	Gene names	C10orf86
Domain Architecture	No domain graphic available
Description	Protein C10orf86.

GPTC8_HUMAN
θ value	0.21417 (rank : 41)	NC score	0.057180 (rank : 34)
Query Neighborhood Hits	184	Target Neighborhood Hits	366	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

SREC2_HUMAN
θ value	0.21417 (rank : 42)	NC score	0.021818 (rank : 111)
Query Neighborhood Hits	184	Target Neighborhood Hits	645	Shared Neighborhood Hits	29
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TCF19_MOUSE
θ value	0.279714 (rank : 43)	NC score	0.046970 (rank : 46)
Query Neighborhood Hits	184	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

WIRE_MOUSE
θ value	0.279714 (rank : 44)	NC score	0.068883 (rank : 22)
Query Neighborhood Hits	184	Target Neighborhood Hits	310	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

HCFC1_MOUSE
θ value	0.365318 (rank : 45)	NC score	0.037579 (rank : 65)
Query Neighborhood Hits	184	Target Neighborhood Hits	348	Shared Neighborhood Hits	25
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

ITCH_MOUSE
θ value	0.365318 (rank : 46)	NC score	0.020048 (rank : 114)
Query Neighborhood Hits	184	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

RGS3_MOUSE
θ value	0.365318 (rank : 47)	NC score	0.053373 (rank : 37)
Query Neighborhood Hits	184	Target Neighborhood Hits	1621	Shared Neighborhood Hits	115
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

HORN_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.028074 (rank : 95)
Query Neighborhood Hits	184	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

PDC6I_HUMAN
θ value	0.47712 (rank : 49)	NC score	0.041779 (rank : 56)
Query Neighborhood Hits	184	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

WIRE_HUMAN
θ value	0.47712 (rank : 50)	NC score	0.066009 (rank : 23)
Query Neighborhood Hits	184	Target Neighborhood Hits	329	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

TARSH_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.055552 (rank : 36)
Query Neighborhood Hits	184	Target Neighborhood Hits	768	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

VATA1_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.032636 (rank : 82)
Query Neighborhood Hits	184	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P50516	Gene names	Atp6v1a, Atp6a1, Atp6a2, Atp6v1a1
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1).

ADA29_HUMAN
θ value	0.813845 (rank : 53)	NC score	0.009905 (rank : 149)
Query Neighborhood Hits	184	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

AFF1_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.059666 (rank : 30)
Query Neighborhood Hits	184	Target Neighborhood Hits	506	Shared Neighborhood Hits	42
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

APC_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.045765 (rank : 49)
Query Neighborhood Hits	184	Target Neighborhood Hits	603	Shared Neighborhood Hits	50
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ERBB2_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.002644 (rank : 176)
Query Neighborhood Hits	184	Target Neighborhood Hits	918	Shared Neighborhood Hits	15
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ITCH_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.018924 (rank : 118)
Query Neighborhood Hits	184	Target Neighborhood Hits	162	Shared Neighborhood Hits	14
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

NEB2_MOUSE
θ value	0.813845 (rank : 58)	NC score	0.017275 (rank : 122)
Query Neighborhood Hits	184	Target Neighborhood Hits	889	Shared Neighborhood Hits	27
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

CABIN_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.048259 (rank : 43)
Query Neighborhood Hits	184	Target Neighborhood Hits	490	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

GNAS3_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.060379 (rank : 28)
Query Neighborhood Hits	184	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

GON4L_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.030589 (rank : 86)
Query Neighborhood Hits	184	Target Neighborhood Hits	455	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HCFC1_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.034741 (rank : 75)
Query Neighborhood Hits	184	Target Neighborhood Hits	331	Shared Neighborhood Hits	23
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MAP1B_MOUSE
θ value	1.06291 (rank : 63)	NC score	0.035053 (rank : 72)
Query Neighborhood Hits	184	Target Neighborhood Hits	977	Shared Neighborhood Hits	49
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAST1_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.004705 (rank : 168)
Query Neighborhood Hits	184	Target Neighborhood Hits	1146	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MUC13_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.037900 (rank : 64)
Query Neighborhood Hits	184	Target Neighborhood Hits	447	Shared Neighborhood Hits	31
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PI5PA_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.035893 (rank : 69)
Query Neighborhood Hits	184	Target Neighborhood Hits	331	Shared Neighborhood Hits	36
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RERE_MOUSE
θ value	1.06291 (rank : 67)	NC score	0.031983 (rank : 84)
Query Neighborhood Hits	184	Target Neighborhood Hits	785	Shared Neighborhood Hits	41
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RFIP1_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.031875 (rank : 85)
Query Neighborhood Hits	184	Target Neighborhood Hits	236	Shared Neighborhood Hits	21
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TCGAP_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.032954 (rank : 81)
Query Neighborhood Hits	184	Target Neighborhood Hits	872	Shared Neighborhood Hits	54
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

VINEX_MOUSE
θ value	1.06291 (rank : 70)	NC score	0.020964 (rank : 113)
Query Neighborhood Hits	184	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

YLPM1_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.048290 (rank : 42)
Query Neighborhood Hits	184	Target Neighborhood Hits	670	Shared Neighborhood Hits	60
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

5NT1B_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.026817 (rank : 97)
Query Neighborhood Hits	184	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

DMP1_MOUSE
θ value	1.38821 (rank : 73)	NC score	0.033535 (rank : 79)
Query Neighborhood Hits	184	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

H6ST3_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.019910 (rank : 115)
Query Neighborhood Hits	184	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

KI21A_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.006236 (rank : 165)
Query Neighborhood Hits	184	Target Neighborhood Hits	1317	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MAGI1_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.019649 (rank : 117)
Query Neighborhood Hits	184	Target Neighborhood Hits	403	Shared Neighborhood Hits	25
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MBB1A_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.050784 (rank : 40)
Query Neighborhood Hits	184	Target Neighborhood Hits	665	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NEUM_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.041703 (rank : 57)
Query Neighborhood Hits	184	Target Neighborhood Hits	132	Shared Neighborhood Hits	14
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NKX61_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.010922 (rank : 145)
Query Neighborhood Hits	184	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

PRP1_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.041880 (rank : 55)
Query Neighborhood Hits	184	Target Neighborhood Hits	385	Shared Neighborhood Hits	36
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SEBP2_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.029380 (rank : 91)
Query Neighborhood Hits	184	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

TARA_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.038599 (rank : 61)
Query Neighborhood Hits	184	Target Neighborhood Hits	1133	Shared Neighborhood Hits	68
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

VATA1_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.029741 (rank : 89)
Query Neighborhood Hits	184	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P38606, Q96DY6, Q9UHY3	Gene names	ATP6V1A, ATP6A1, ATP6V1A1, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68).

ZN406_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.000062 (rank : 181)
Query Neighborhood Hits	184	Target Neighborhood Hits	800	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.

APC_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.036639 (rank : 67)
Query Neighborhood Hits	184	Target Neighborhood Hits	441	Shared Neighborhood Hits	22
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

GRIN1_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.045849 (rank : 48)
Query Neighborhood Hits	184	Target Neighborhood Hits	337	Shared Neighborhood Hits	46
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MAML3_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.029029 (rank : 93)
Query Neighborhood Hits	184	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

PDC6I_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.033197 (rank : 80)
Query Neighborhood Hits	184	Target Neighborhood Hits	275	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PI5PA_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.038054 (rank : 63)
Query Neighborhood Hits	184	Target Neighborhood Hits	749	Shared Neighborhood Hits	64
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RIN3_MOUSE
θ value	1.81305 (rank : 90)	NC score	0.023153 (rank : 105)
Query Neighborhood Hits	184	Target Neighborhood Hits	239	Shared Neighborhood Hits	20
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RP1L1_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.028953 (rank : 94)
Query Neighborhood Hits	184	Target Neighborhood Hits	1072	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SREC2_MOUSE
θ value	1.81305 (rank : 92)	NC score	0.016500 (rank : 125)
Query Neighborhood Hits	184	Target Neighborhood Hits	605	Shared Neighborhood Hits	24
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TCGAP_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.023627 (rank : 103)
Query Neighborhood Hits	184	Target Neighborhood Hits	409	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

3BP1_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.022206 (rank : 110)
Query Neighborhood Hits	184	Target Neighborhood Hits	376	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AB1IP_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.024929 (rank : 102)
Query Neighborhood Hits	184	Target Neighborhood Hits	213	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AFF4_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.046611 (rank : 47)
Query Neighborhood Hits	184	Target Neighborhood Hits	611	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CI047_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.038375 (rank : 62)
Query Neighborhood Hits	184	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZRZ4, Q5SQD7, Q7Z568, Q8N1V4	Gene names	C9orf47
Domain Architecture	No domain graphic available
Description	Protein C9orf47 precursor.

EGLN1_HUMAN
θ value	2.36792 (rank : 98)	NC score	0.016911 (rank : 123)
Query Neighborhood Hits	184	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

MUC1_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.045440 (rank : 50)
Query Neighborhood Hits	184	Target Neighborhood Hits	975	Shared Neighborhood Hits	74
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RAPH1_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.035445 (rank : 71)
Query Neighborhood Hits	184	Target Neighborhood Hits	593	Shared Neighborhood Hits	50
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RENT1_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.013721 (rank : 134)
Query Neighborhood Hits	184	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

YAP1_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.026035 (rank : 99)
Query Neighborhood Hits	184	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

BAT2_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.044629 (rank : 52)
Query Neighborhood Hits	184	Target Neighborhood Hits	931	Shared Neighborhood Hits	76
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MLL2_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.022994 (rank : 106)
Query Neighborhood Hits	184	Target Neighborhood Hits	1788	Shared Neighborhood Hits	72
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYLK2_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.001465 (rank : 177)
Query Neighborhood Hits	184	Target Neighborhood Hits	920	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

NACAM_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.056401 (rank : 35)
Query Neighborhood Hits	184	Target Neighborhood Hits	1866	Shared Neighborhood Hits	112
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NRP2_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.009344 (rank : 152)
Query Neighborhood Hits	184	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

TGON2_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.059682 (rank : 29)
Query Neighborhood Hits	184	Target Neighborhood Hits	1037	Shared Neighborhood Hits	81
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TTBK1_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.009177 (rank : 153)
Query Neighborhood Hits	184	Target Neighborhood Hits	1058	Shared Neighborhood Hits	47
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

WRIP1_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.026483 (rank : 98)
Query Neighborhood Hits	184	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.026022 (rank : 100)
Query Neighborhood Hits	184	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

ADA2A_MOUSE
θ value	4.03905 (rank : 112)	NC score	-0.001218 (rank : 184)
Query Neighborhood Hits	184	Target Neighborhood Hits	900	Shared Neighborhood Hits	6
SwissProt Accessions	Q01338	Gene names	Adra2a
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR).

AT2B1_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.005517 (rank : 166)
Query Neighborhood Hits	184	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P20020, Q12992, Q12993, Q13819, Q13820, Q13821, Q16504, Q93082	Gene names	ATP2B1, PMCA1
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 1 (EC 3.6.3.8) (PMCA1) (Plasma membrane calcium pump isoform 1) (Plasma membrane calcium ATPase isoform 1).

ATX2_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.033634 (rank : 78)
Query Neighborhood Hits	184	Target Neighborhood Hits	445	Shared Neighborhood Hits	45
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CRYL1_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.017827 (rank : 120)
Query Neighborhood Hits	184	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KP3, Q542R9, Q8R4W7	Gene names	Cryl1, Cry
Domain Architecture
Description	Lambda-crystallin homolog.

DSPP_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.025384 (rank : 101)
Query Neighborhood Hits	184	Target Neighborhood Hits	645	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

F104A_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.033665 (rank : 77)
Query Neighborhood Hits	184	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q969W3	Gene names	FAM104A
Domain Architecture	No domain graphic available
Description	Protein FAM104A.

JPH4_MOUSE
θ value	4.03905 (rank : 118)	NC score	0.010974 (rank : 144)
Query Neighborhood Hits	184	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

KLC2_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.008436 (rank : 158)
Query Neighborhood Hits	184	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

NFH_MOUSE
θ value	4.03905 (rank : 120)	NC score	0.034889 (rank : 74)
Query Neighborhood Hits	184	Target Neighborhood Hits	2247	Shared Neighborhood Hits	110
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NRP2_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.008707 (rank : 157)
Query Neighborhood Hits	184	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PXK_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.013698 (rank : 135)
Query Neighborhood Hits	184	Target Neighborhood Hits	320	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

ROBO4_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.008397 (rank : 159)
Query Neighborhood Hits	184	Target Neighborhood Hits	358	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SEC63_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.015501 (rank : 128)
Query Neighborhood Hits	184	Target Neighborhood Hits	586	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SRRM1_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.053067 (rank : 38)
Query Neighborhood Hits	184	Target Neighborhood Hits	966	Shared Neighborhood Hits	69
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TRRAP_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.013752 (rank : 133)
Query Neighborhood Hits	184	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

ZFY16_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.010713 (rank : 147)
Query Neighborhood Hits	184	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZN524_MOUSE
θ value	4.03905 (rank : 128)	NC score	-0.001598 (rank : 185)
Query Neighborhood Hits	184	Target Neighborhood Hits	712	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0B1, Q9DCQ0	Gene names	Znf524, Zfp524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.

ATX2_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.029052 (rank : 92)
Query Neighborhood Hits	184	Target Neighborhood Hits	375	Shared Neighborhood Hits	37
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CCD37_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.022296 (rank : 109)
Query Neighborhood Hits	184	Target Neighborhood Hits	199	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CD99_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.061484 (rank : 27)
Query Neighborhood Hits	184	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCN6, Q4L299, Q4L2A4, Q8BLN1	Gene names	Cd99, Pilrl
Domain Architecture	No domain graphic available
Description	CD99 antigen precursor (Paired immunoglobin-like type 2 receptor- ligand) (PILR-L).

CDT1_MOUSE
θ value	5.27518 (rank : 132)	NC score	0.019797 (rank : 116)
Query Neighborhood Hits	184	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

DUET_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.001219 (rank : 178)
Query Neighborhood Hits	184	Target Neighborhood Hits	1220	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

EP400_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.013982 (rank : 131)
Query Neighborhood Hits	184	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FEZ1_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.012838 (rank : 138)
Query Neighborhood Hits	184	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0X8	Gene names	Fez1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

FXR2_MOUSE
θ value	5.27518 (rank : 136)	NC score	0.012687 (rank : 139)
Query Neighborhood Hits	184	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

JHD2C_MOUSE
θ value	5.27518 (rank : 137)	NC score	0.016254 (rank : 126)
Query Neighborhood Hits	184	Target Neighborhood Hits	297	Shared Neighborhood Hits	26
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

MICA1_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.009102 (rank : 155)
Query Neighborhood Hits	184	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

OXRP_HUMAN
θ value	5.27518 (rank : 139)	NC score	0.013865 (rank : 132)
Query Neighborhood Hits	184	Target Neighborhood Hits	544	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PGCA_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.011384 (rank : 141)
Query Neighborhood Hits	184	Target Neighborhood Hits	821	Shared Neighborhood Hits	33
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

ROBO3_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.004472 (rank : 169)
Query Neighborhood Hits	184	Target Neighborhood Hits	570	Shared Neighborhood Hits	19
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

SIN3A_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.013668 (rank : 136)
Query Neighborhood Hits	184	Target Neighborhood Hits	180	Shared Neighborhood Hits	15
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

UBP11_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.009507 (rank : 151)
Query Neighborhood Hits	184	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

WNK1_MOUSE
θ value	5.27518 (rank : 144)	NC score	0.003480 (rank : 172)
Query Neighborhood Hits	184	Target Neighborhood Hits	1179	Shared Neighborhood Hits	39
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

AFF4_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.047349 (rank : 45)
Query Neighborhood Hits	184	Target Neighborhood Hits	581	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

B3A3_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.008060 (rank : 160)
Query Neighborhood Hits	184	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

DSPP_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.023533 (rank : 104)
Query Neighborhood Hits	184	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FOXH1_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.010093 (rank : 148)
Query Neighborhood Hits	184	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

GLP1R_MOUSE
θ value	6.88961 (rank : 149)	NC score	0.003637 (rank : 171)
Query Neighborhood Hits	184	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

JADE2_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.009153 (rank : 154)
Query Neighborhood Hits	184	Target Neighborhood Hits	199	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

MAP1B_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.029441 (rank : 90)
Query Neighborhood Hits	184	Target Neighborhood Hits	903	Shared Neighborhood Hits	46
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MYO15_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.009532 (rank : 150)
Query Neighborhood Hits	184	Target Neighborhood Hits	671	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NKX61_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.007471 (rank : 161)
Query Neighborhood Hits	184	Target Neighborhood Hits	439	Shared Neighborhood Hits	16
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

PCDGJ_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.000145 (rank : 180)
Query Neighborhood Hits	184	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5F8, Q9UN63	Gene names	PCDHGB7
Domain Architecture
Description	Protocadherin gamma B7 precursor (PCDH-gamma-B7).

PCQAP_MOUSE
θ value	6.88961 (rank : 155)	NC score	0.022580 (rank : 108)
Query Neighborhood Hits	184	Target Neighborhood Hits	506	Shared Neighborhood Hits	29
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

RANB9_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.015349 (rank : 129)
Query Neighborhood Hits	184	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	P69566	Gene names	Ranbp9, Ranbpm
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (Ran-binding protein M) (RanBPM) (B cell antigen receptor Ig beta-associated protein 1) (IBAP-1).

ROR2_HUMAN
θ value	6.88961 (rank : 157)	NC score	-0.000791 (rank : 182)
Query Neighborhood Hits	184	Target Neighborhood Hits	1014	Shared Neighborhood Hits	10
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

TBX2_MOUSE
θ value	6.88961 (rank : 158)	NC score	0.006303 (rank : 164)
Query Neighborhood Hits	184	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TCF20_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.021618 (rank : 112)
Query Neighborhood Hits	184	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TMPSD_MOUSE
θ value	6.88961 (rank : 160)	NC score	0.003219 (rank : 173)
Query Neighborhood Hits	184	Target Neighborhood Hits	334	Shared Neighborhood Hits	19
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

VILL_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.005481 (rank : 167)
Query Neighborhood Hits	184	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YD6, P97809, Q8BIS5, Q8R211, Q8VDI8	Gene names	Vill, Villp
Domain Architecture	No domain graphic available
Description	Villin-like protein (EF-6).

ZN592_MOUSE
θ value	6.88961 (rank : 162)	NC score	0.000665 (rank : 179)
Query Neighborhood Hits	184	Target Neighborhood Hits	768	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

4ET_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.011137 (rank : 143)
Query Neighborhood Hits	184	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

AFF3_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.037012 (rank : 66)
Query Neighborhood Hits	184	Target Neighborhood Hits	190	Shared Neighborhood Hits	26
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

E2AK2_MOUSE
θ value	8.99809 (rank : 165)	NC score	-0.001198 (rank : 183)
Query Neighborhood Hits	184	Target Neighborhood Hits	864	Shared Neighborhood Hits	11
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

ENAM_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.018786 (rank : 119)
Query Neighborhood Hits	184	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

HERC3_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.010772 (rank : 146)
Query Neighborhood Hits	184	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

JHD2A_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.012322 (rank : 140)
Query Neighborhood Hits	184	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

KIF11_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.002750 (rank : 174)
Query Neighborhood Hits	184	Target Neighborhood Hits	583	Shared Neighborhood Hits	8
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

MLL4_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.017552 (rank : 121)
Query Neighborhood Hits	184	Target Neighborhood Hits	722	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PHLB1_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.013341 (rank : 137)
Query Neighborhood Hits	184	Target Neighborhood Hits	678	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKP4_MOUSE
θ value	8.99809 (rank : 172)	NC score	0.007209 (rank : 163)
Query Neighborhood Hits	184	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

RANB9_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.016594 (rank : 124)
Query Neighborhood Hits	184	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RGS3_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.034740 (rank : 76)
Query Neighborhood Hits	184	Target Neighborhood Hits	1375	Shared Neighborhood Hits	95
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SGPP1_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.008884 (rank : 156)
Query Neighborhood Hits	184	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JI99	Gene names	Sgpp1, Spp1, Spph1
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 1 (EC 3.1.3.-) (Sphingosine-1- phosphatase 1) (SPPase1) (SPP) (mSPP1).

SRRM1_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.039702 (rank : 59)
Query Neighborhood Hits	184	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SYNJ1_MOUSE
θ value	8.99809 (rank : 177)	NC score	0.022809 (rank : 107)
Query Neighborhood Hits	184	Target Neighborhood Hits	516	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TACC2_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.014237 (rank : 130)
Query Neighborhood Hits	184	Target Neighborhood Hits	856	Shared Neighborhood Hits	44
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TCOF_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.030157 (rank : 88)
Query Neighborhood Hits	184	Target Neighborhood Hits	471	Shared Neighborhood Hits	36
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TMPSD_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.002735 (rank : 175)
Query Neighborhood Hits	184	Target Neighborhood Hits	333	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TTBK2_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.004189 (rank : 170)
Query Neighborhood Hits	184	Target Neighborhood Hits	822	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

VCY1_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.036096 (rank : 68)
Query Neighborhood Hits	184	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

X3CL1_MOUSE
θ value	8.99809 (rank : 183)	NC score	0.011211 (rank : 142)
Query Neighborhood Hits	184	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	O35188, O35933	Gene names	Cx3cl1, Cx3c, Fkn, Scyd1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ZFYV1_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.007234 (rank : 162)
Query Neighborhood Hits	184	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

TARA_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.051234 (rank : 39)
Query Neighborhood Hits	184	Target Neighborhood Hits	1626	Shared Neighborhood Hits	98
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

Hits sorted by NC score

COA2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	184	Target Neighborhood Hits	184	Shared Neighborhood Hits	184
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

COA1_HUMAN
NC score	0.968167 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	184	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

PCCA_HUMAN
NC score	0.790805 (rank : 3)	θ value	2.10721e-57 (rank : 3)
Query Neighborhood Hits	184	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	P05165, Q15979	Gene names	PCCA
Domain Architecture
Description	Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).

PCCA_MOUSE
NC score	0.790193 (rank : 4)	θ value	2.32979e-56 (rank : 4)
Query Neighborhood Hits	184	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZA3, Q80VU5, Q922N3	Gene names	Pcca
Domain Architecture	No domain graphic available
Description	Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit alpha) (Propanoyl-CoA:carbon dioxide ligase subunit alpha).

MCCA_MOUSE
NC score	0.786731 (rank : 5)	θ value	6.34462e-54 (rank : 6)
Query Neighborhood Hits	184	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MR8, Q3TGU0, Q9D8R2	Gene names	Mccc1, Mcca
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

MCCA_HUMAN
NC score	0.785866 (rank : 6)	θ value	1.51013e-55 (rank : 5)
Query Neighborhood Hits	184	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RQ3, Q59ES4, Q9H959, Q9NS97	Gene names	MCCC1, MCCA
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

PYC_MOUSE
NC score	0.760277 (rank : 7)	θ value	9.48078e-50 (rank : 7)
Query Neighborhood Hits	184	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q05920	Gene names	Pc, Pcx
Domain Architecture
Description	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).

PYC_HUMAN
NC score	0.759553 (rank : 8)	θ value	2.1121e-49 (rank : 8)
Query Neighborhood Hits	184	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	P11498, Q16705	Gene names	PC
Domain Architecture
Description	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB).

PCCB_MOUSE
NC score	0.363728 (rank : 9)	θ value	7.58209e-15 (rank : 9)
Query Neighborhood Hits	184	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MN9	Gene names	Pccb
Domain Architecture	No domain graphic available
Description	Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).

PCCB_HUMAN
NC score	0.358422 (rank : 10)	θ value	2.88119e-14 (rank : 10)
Query Neighborhood Hits	184	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	P05166, Q16813	Gene names	PCCB
Domain Architecture
Description	Propionyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.3) (PCCase subunit beta) (Propanoyl-CoA:carbon dioxide ligase subunit beta).

PYR1_HUMAN
NC score	0.351412 (rank : 11)	θ value	7.34386e-10 (rank : 11)
Query Neighborhood Hits	184	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

CPSM_MOUSE
NC score	0.344981 (rank : 12)	θ value	1.43324e-05 (rank : 13)
Query Neighborhood Hits	184	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C196, Q6NX75	Gene names	Cps1
Domain Architecture	No domain graphic available
Description	Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).

CPSM_HUMAN
NC score	0.344931 (rank : 13)	θ value	1.69304e-06 (rank : 12)
Query Neighborhood Hits	184	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	P31327, O43774, Q7Z5I5	Gene names	CPS1
Domain Architecture
Description	Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).

MCCC2_HUMAN
NC score	0.249906 (rank : 14)	θ value	9.29e-05 (rank : 14)
Query Neighborhood Hits	184	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCC0, Q96C27, Q9Y4L7	Gene names	MCCC2, MCCB
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial precursor (EC 6.4.1.4) (3-Methylcrotonyl-CoA carboxylase 2) (MCCase subunit beta) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) (3- Methylcrotonyl-CoA carboxylase non-biotin-containing subunit).

SYN2_MOUSE
NC score	0.082046 (rank : 15)	θ value	0.000461057 (rank : 15)
Query Neighborhood Hits	184	Target Neighborhood Hits	183	Shared Neighborhood Hits	25
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

SYN2_HUMAN
NC score	0.078893 (rank : 16)	θ value	0.000602161 (rank : 16)
Query Neighborhood Hits	184	Target Neighborhood Hits	213	Shared Neighborhood Hits	19
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

WASIP_MOUSE
NC score	0.076758 (rank : 17)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	184	Target Neighborhood Hits	392	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

NPBL_MOUSE
NC score	0.073050 (rank : 18)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	184	Target Neighborhood Hits	1041	Shared Neighborhood Hits	66
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

WASIP_HUMAN
NC score	0.072032 (rank : 19)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	184	Target Neighborhood Hits	458	Shared Neighborhood Hits	33
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SRRM2_MOUSE
NC score	0.071301 (rank : 20)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	184	Target Neighborhood Hits	1470	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM2_HUMAN
NC score	0.070718 (rank : 21)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	184	Target Neighborhood Hits	1296	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

WIRE_MOUSE
NC score	0.068883 (rank : 22)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	184	Target Neighborhood Hits	310	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

WIRE_HUMAN
NC score	0.066009 (rank : 23)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	184	Target Neighborhood Hits	329	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

CJ086_HUMAN
NC score	0.064889 (rank : 24)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	184	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NXX6, Q5SQQ5, Q6P673, Q8WY66, Q9BS90	Gene names	C10orf86
Domain Architecture	No domain graphic available
Description	Protein C10orf86.

NIPBL_HUMAN
NC score	0.064686 (rank : 25)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	184	Target Neighborhood Hits	1311	Shared Neighborhood Hits	67
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

AFF1_MOUSE
NC score	0.064092 (rank : 26)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	184	Target Neighborhood Hits	351	Shared Neighborhood Hits	28
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CD99_MOUSE
NC score	0.061484 (rank : 27)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	184	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCN6, Q4L299, Q4L2A4, Q8BLN1	Gene names	Cd99, Pilrl
Domain Architecture	No domain graphic available
Description	CD99 antigen precursor (Paired immunoglobin-like type 2 receptor- ligand) (PILR-L).

GNAS3_HUMAN
NC score	0.060379 (rank : 28)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	184	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

TGON2_HUMAN
NC score	0.059682 (rank : 29)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	184	Target Neighborhood Hits	1037	Shared Neighborhood Hits	81
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

AFF1_HUMAN
NC score	0.059666 (rank : 30)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	184	Target Neighborhood Hits	506	Shared Neighborhood Hits	42
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

NOLC1_HUMAN
NC score	0.059069 (rank : 31)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	184	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

XRCC1_MOUSE
NC score	0.057658 (rank : 32)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	184	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

PININ_MOUSE
NC score	0.057596 (rank : 33)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	184	Target Neighborhood Hits	777	Shared Neighborhood Hits	25
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

GPTC8_HUMAN
NC score	0.057180 (rank : 34)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	184	Target Neighborhood Hits	366	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

NACAM_MOUSE
NC score	0.056401 (rank : 35)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	184	Target Neighborhood Hits	1866	Shared Neighborhood Hits	112
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TARSH_HUMAN
NC score	0.055552 (rank : 36)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	184	Target Neighborhood Hits	768	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

RGS3_MOUSE
NC score	0.053373 (rank : 37)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	184	Target Neighborhood Hits	1621	Shared Neighborhood Hits	115
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SRRM1_MOUSE
NC score	0.053067 (rank : 38)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	184	Target Neighborhood Hits	966	Shared Neighborhood Hits	69
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TARA_HUMAN
NC score	0.051234 (rank : 39)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	184	Target Neighborhood Hits	1626	Shared Neighborhood Hits	98
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MBB1A_HUMAN
NC score	0.050784 (rank : 40)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	184	Target Neighborhood Hits	665	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PININ_HUMAN
NC score	0.048962 (rank : 41)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	184	Target Neighborhood Hits	753	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

YLPM1_HUMAN
NC score	0.048290 (rank : 42)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	184	Target Neighborhood Hits	670	Shared Neighborhood Hits	60
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CABIN_HUMAN
NC score	0.048259 (rank : 43)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	184	Target Neighborhood Hits	490	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

ELOA3_HUMAN
NC score	0.047363 (rank : 44)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	184	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

AFF4_MOUSE
NC score	0.047349 (rank : 45)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	184	Target Neighborhood Hits	581	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

TCF19_MOUSE
NC score	0.046970 (rank : 46)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	184	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

AFF4_HUMAN
NC score	0.046611 (rank : 47)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	184	Target Neighborhood Hits	611	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

GRIN1_MOUSE
NC score	0.045849 (rank : 48)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	184	Target Neighborhood Hits	337	Shared Neighborhood Hits	46
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

APC_HUMAN
NC score	0.045765 (rank : 49)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	184	Target Neighborhood Hits	603	Shared Neighborhood Hits	50
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

MUC1_HUMAN
NC score	0.045440 (rank : 50)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	184	Target Neighborhood Hits	975	Shared Neighborhood Hits	74
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PCLO_HUMAN
NC score	0.045396 (rank : 51)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	184	Target Neighborhood Hits	2046	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

BAT2_HUMAN
NC score	0.044629 (rank : 52)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	184	Target Neighborhood Hits	931	Shared Neighborhood Hits	76
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SH3K1_HUMAN
NC score	0.042663 (rank : 53)	θ value	0.0252991 (rank : 19)
Query Neighborhood Hits	184	Target Neighborhood Hits	341	Shared Neighborhood Hits	12
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

PRG4_MOUSE
NC score	0.042326 (rank : 54)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	184	Target Neighborhood Hits	624	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
NC score	0.041880 (rank : 55)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	184	Target Neighborhood Hits	385	Shared Neighborhood Hits	36
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PDC6I_HUMAN
NC score	0.041779 (rank : 56)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	184	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

NEUM_HUMAN
NC score	0.041703 (rank : 57)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	184	Target Neighborhood Hits	132	Shared Neighborhood Hits	14
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

SH3K1_MOUSE
NC score	0.041095 (rank : 58)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	184	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SRRM1_HUMAN
NC score	0.039702 (rank : 59)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	184	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MYCB2_MOUSE
NC score	0.039051 (rank : 60)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	184	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TARA_MOUSE
NC score	0.038599 (rank : 61)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	184	Target Neighborhood Hits	1133	Shared Neighborhood Hits	68
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CI047_HUMAN
NC score	0.038375 (rank : 62)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	184	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZRZ4, Q5SQD7, Q7Z568, Q8N1V4	Gene names	C9orf47
Domain Architecture	No domain graphic available
Description	Protein C9orf47 precursor.

PI5PA_HUMAN
NC score	0.038054 (rank : 63)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	184	Target Neighborhood Hits	749	Shared Neighborhood Hits	64
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MUC13_MOUSE
NC score	0.037900 (rank : 64)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	184	Target Neighborhood Hits	447	Shared Neighborhood Hits	31
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

HCFC1_MOUSE
NC score	0.037579 (rank : 65)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	184	Target Neighborhood Hits	348	Shared Neighborhood Hits	25
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

AFF3_HUMAN
NC score	0.037012 (rank : 66)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	184	Target Neighborhood Hits	190	Shared Neighborhood Hits	26
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

APC_MOUSE
NC score	0.036639 (rank : 67)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	184	Target Neighborhood Hits	441	Shared Neighborhood Hits	22
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

VCY1_HUMAN
NC score	0.036096 (rank : 68)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	184	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

PI5PA_MOUSE
NC score	0.035893 (rank : 69)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	184	Target Neighborhood Hits	331	Shared Neighborhood Hits	36
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHA6_HUMAN
NC score	0.035718 (rank : 70)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	184	Target Neighborhood Hits	556	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RAPH1_HUMAN
NC score	0.035445 (rank : 71)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	184	Target Neighborhood Hits	593	Shared Neighborhood Hits	50
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

MAP1B_MOUSE
NC score	0.035053 (rank : 72)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	184	Target Neighborhood Hits	977	Shared Neighborhood Hits	49
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MEGF9_MOUSE
NC score	0.035040 (rank : 73)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	184	Target Neighborhood Hits	896	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NFH_MOUSE
NC score	0.034889 (rank : 74)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	184	Target Neighborhood Hits	2247	Shared Neighborhood Hits	110
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

HCFC1_HUMAN
NC score	0.034741 (rank : 75)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	184	Target Neighborhood Hits	331	Shared Neighborhood Hits	23
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

RGS3_HUMAN
NC score	0.034740 (rank : 76)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	184	Target Neighborhood Hits	1375	Shared Neighborhood Hits	95
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

F104A_HUMAN
NC score	0.033665 (rank : 77)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	184	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q969W3	Gene names	FAM104A
Domain Architecture	No domain graphic available
Description	Protein FAM104A.

ATX2_MOUSE
NC score	0.033634 (rank : 78)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	184	Target Neighborhood Hits	445	Shared Neighborhood Hits	45
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

DMP1_MOUSE
NC score	0.033535 (rank : 79)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	184	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

PDC6I_MOUSE
NC score	0.033197 (rank : 80)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	184	Target Neighborhood Hits	275	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

TCGAP_HUMAN
NC score	0.032954 (rank : 81)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	184	Target Neighborhood Hits	872	Shared Neighborhood Hits	54
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

VATA1_MOUSE
NC score	0.032636 (rank : 82)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	184	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P50516	Gene names	Atp6v1a, Atp6a1, Atp6a2, Atp6v1a1
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1).

UBP31_HUMAN
NC score	0.032601 (rank : 83)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	184	Target Neighborhood Hits	293	Shared Neighborhood Hits	26
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

RERE_MOUSE
NC score	0.031983 (rank : 84)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	184	Target Neighborhood Hits	785	Shared Neighborhood Hits	41
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RFIP1_HUMAN
NC score	0.031875 (rank : 85)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	184	Target Neighborhood Hits	236	Shared Neighborhood Hits	21
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

GON4L_MOUSE
NC score	0.030589 (rank : 86)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	184	Target Neighborhood Hits	455	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

KCNK4_HUMAN
NC score	0.030386 (rank : 87)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	184	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

TCOF_MOUSE
NC score	0.030157 (rank : 88)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	184	Target Neighborhood Hits	471	Shared Neighborhood Hits	36
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

VATA1_HUMAN
NC score	0.029741 (rank : 89)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	184	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P38606, Q96DY6, Q9UHY3	Gene names	ATP6V1A, ATP6A1, ATP6V1A1, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68).

MAP1B_HUMAN
NC score	0.029441 (rank : 90)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	184	Target Neighborhood Hits	903	Shared Neighborhood Hits	46
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SEBP2_HUMAN
NC score	0.029380 (rank : 91)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	184	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

ATX2_HUMAN
NC score	0.029052 (rank : 92)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	184	Target Neighborhood Hits	375	Shared Neighborhood Hits	37
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

MAML3_HUMAN
NC score	0.029029 (rank : 93)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	184	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

RP1L1_HUMAN
NC score	0.028953 (rank : 94)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	184	Target Neighborhood Hits	1072	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

HORN_MOUSE
NC score	0.028074 (rank : 95)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	184	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

PO6F2_MOUSE
NC score	0.028019 (rank : 96)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	184	Target Neighborhood Hits	639	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

5NT1B_HUMAN
NC score	0.026817 (rank : 97)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	184	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

WRIP1_HUMAN
NC score	0.026483 (rank : 98)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	184	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

YAP1_HUMAN
NC score	0.026035 (rank : 99)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	184	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

WRIP1_MOUSE
NC score	0.026022 (rank : 100)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	184	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

DSPP_HUMAN
NC score	0.025384 (rank : 101)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	184	Target Neighborhood Hits	645	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

AB1IP_HUMAN
NC score	0.024929 (rank : 102)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	184	Target Neighborhood Hits	213	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

TCGAP_MOUSE
NC score	0.023627 (rank : 103)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	184	Target Neighborhood Hits	409	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

DSPP_MOUSE
NC score	0.023533 (rank : 104)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	184	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RIN3_MOUSE
NC score	0.023153 (rank : 105)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	184	Target Neighborhood Hits	239	Shared Neighborhood Hits	20
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

MLL2_HUMAN
NC score	0.022994 (rank : 106)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	184	Target Neighborhood Hits	1788	Shared Neighborhood Hits	72
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SYNJ1_MOUSE
NC score	0.022809 (rank : 107)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	184	Target Neighborhood Hits	516	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PCQAP_MOUSE
NC score	0.022580 (rank : 108)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	184	Target Neighborhood Hits	506	Shared Neighborhood Hits	29
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

CCD37_MOUSE
NC score	0.022296 (rank : 109)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	184	Target Neighborhood Hits	199	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

3BP1_HUMAN
NC score	0.022206 (rank : 110)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	184	Target Neighborhood Hits	376	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

SREC2_HUMAN
NC score	0.021818 (rank : 111)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	184	Target Neighborhood Hits	645	Shared Neighborhood Hits	29
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TCF20_HUMAN
NC score	0.021618 (rank : 112)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	184	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

VINEX_MOUSE
NC score	0.020964 (rank : 113)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	184	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ITCH_MOUSE
NC score	0.020048 (rank : 114)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	184	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

H6ST3_HUMAN
NC score	0.019910 (rank : 115)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	184	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

CDT1_MOUSE
NC score	0.019797 (rank : 116)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	184	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

MAGI1_MOUSE
NC score	0.019649 (rank : 117)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	184	Target Neighborhood Hits	403	Shared Neighborhood Hits	25
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

ITCH_HUMAN
NC score	0.018924 (rank : 118)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	184	Target Neighborhood Hits	162	Shared Neighborhood Hits	14
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ENAM_HUMAN
NC score	0.018786 (rank : 119)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	184	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

CRYL1_MOUSE
NC score	0.017827 (rank : 120)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	184	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KP3, Q542R9, Q8R4W7	Gene names	Cryl1, Cry
Domain Architecture
Description	Lambda-crystallin homolog.

MLL4_HUMAN
NC score	0.017552 (rank : 121)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	184	Target Neighborhood Hits	722	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NEB2_MOUSE
NC score	0.017275 (rank : 122)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	184	Target Neighborhood Hits	889	Shared Neighborhood Hits	27
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

EGLN1_HUMAN
NC score	0.016911 (rank : 123)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	184	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

RANB9_HUMAN
NC score	0.016594 (rank : 124)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	184	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

SREC2_MOUSE
NC score	0.016500 (rank : 125)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	184	Target Neighborhood Hits	605	Shared Neighborhood Hits	24
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

JHD2C_MOUSE
NC score	0.016254 (rank : 126)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	184	Target Neighborhood Hits	297	Shared Neighborhood Hits	26
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

FOXGB_MOUSE
NC score	0.016226 (rank : 127)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	184	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	Q60987, Q80VP3	Gene names	Foxg1b, Fkhl1, Foxg1, Hfhbf1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1).

SEC63_HUMAN
NC score	0.015501 (rank : 128)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	184	Target Neighborhood Hits	586	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

RANB9_MOUSE
NC score	0.015349 (rank : 129)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	184	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	P69566	Gene names	Ranbp9, Ranbpm
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (Ran-binding protein M) (RanBPM) (B cell antigen receptor Ig beta-associated protein 1) (IBAP-1).

TACC2_HUMAN
NC score	0.014237 (rank : 130)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	184	Target Neighborhood Hits	856	Shared Neighborhood Hits	44
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

EP400_MOUSE
NC score	0.013982 (rank : 131)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	184	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

OXRP_HUMAN
NC score	0.013865 (rank : 132)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	184	Target Neighborhood Hits	544	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

TRRAP_HUMAN
NC score	0.013752 (rank : 133)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	184	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

RENT1_MOUSE
NC score	0.013721 (rank : 134)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	184	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

PXK_MOUSE
NC score	0.013698 (rank : 135)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	184	Target Neighborhood Hits	320	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SIN3A_HUMAN
NC score	0.013668 (rank : 136)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	184	Target Neighborhood Hits	180	Shared Neighborhood Hits	15
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

PHLB1_MOUSE
NC score	0.013341 (rank : 137)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	184	Target Neighborhood Hits	678	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

FEZ1_MOUSE
NC score	0.012838 (rank : 138)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	184	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0X8	Gene names	Fez1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

FXR2_MOUSE
NC score	0.012687 (rank : 139)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	184	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

JHD2A_HUMAN
NC score	0.012322 (rank : 140)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	184	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

PGCA_HUMAN
NC score	0.011384 (rank : 141)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	184	Target Neighborhood Hits	821	Shared Neighborhood Hits	33
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

X3CL1_MOUSE
NC score	0.011211 (rank : 142)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	184	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	O35188, O35933	Gene names	Cx3cl1, Cx3c, Fkn, Scyd1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

4ET_HUMAN
NC score	0.011137 (rank : 143)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	184	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

JPH4_MOUSE
NC score	0.010974 (rank : 144)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	184	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

NKX61_HUMAN
NC score	0.010922 (rank : 145)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	184	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

HERC3_HUMAN
NC score	0.010772 (rank : 146)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	184	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

ZFY16_MOUSE
NC score	0.010713 (rank : 147)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	184	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

FOXH1_HUMAN
NC score	0.010093 (rank : 148)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	184	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

ADA29_HUMAN
NC score	0.009905 (rank : 149)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	184	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

MYO15_HUMAN
NC score	0.009532 (rank : 150)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	184	Target Neighborhood Hits	671	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

UBP11_HUMAN
NC score	0.009507 (rank : 151)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	184	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

NRP2_MOUSE
NC score	0.009344 (rank : 152)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	184	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

TTBK1_HUMAN
NC score	0.009177 (rank : 153)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	184	Target Neighborhood Hits	1058	Shared Neighborhood Hits	47
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

JADE2_HUMAN
NC score	0.009153 (rank : 154)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	184	Target Neighborhood Hits	199	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

MICA1_HUMAN
NC score	0.009102 (rank : 155)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	184	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

SGPP1_MOUSE
NC score	0.008884 (rank : 156)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	184	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JI99	Gene names	Sgpp1, Spp1, Spph1
Domain Architecture
Description	Sphingosine-1-phosphate phosphatase 1 (EC 3.1.3.-) (Sphingosine-1- phosphatase 1) (SPPase1) (SPP) (mSPP1).

NRP2_HUMAN
NC score	0.008707 (rank : 157)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	184	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

KLC2_HUMAN
NC score	0.008436 (rank : 158)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	184	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

ROBO4_MOUSE
NC score	0.008397 (rank : 159)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	184	Target Neighborhood Hits	358	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

B3A3_MOUSE
NC score	0.008060 (rank : 160)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	184	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

NKX61_MOUSE
NC score	0.007471 (rank : 161)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	184	Target Neighborhood Hits	439	Shared Neighborhood Hits	16
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

ZFYV1_HUMAN
NC score	0.007234 (rank : 162)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	184	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

PKP4_MOUSE
NC score	0.007209 (rank : 163)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	184	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

TBX2_MOUSE
NC score	0.006303 (rank : 164)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	184	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q60707	Gene names	Tbx2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

KI21A_MOUSE
NC score	0.006236 (rank : 165)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	184	Target Neighborhood Hits	1317	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

AT2B1_HUMAN
NC score	0.005517 (rank : 166)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	184	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P20020, Q12992, Q12993, Q13819, Q13820, Q13821, Q16504, Q93082	Gene names	ATP2B1, PMCA1
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 1 (EC 3.6.3.8) (PMCA1) (Plasma membrane calcium pump isoform 1) (Plasma membrane calcium ATPase isoform 1).

VILL_MOUSE
NC score	0.005481 (rank : 167)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	184	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YD6, P97809, Q8BIS5, Q8R211, Q8VDI8	Gene names	Vill, Villp
Domain Architecture	No domain graphic available
Description	Villin-like protein (EF-6).

MAST1_HUMAN
NC score	0.004705 (rank : 168)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	184	Target Neighborhood Hits	1146	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ROBO3_HUMAN
NC score	0.004472 (rank : 169)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	184	Target Neighborhood Hits	570	Shared Neighborhood Hits	19
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

TTBK2_HUMAN
NC score	0.004189 (rank : 170)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	184	Target Neighborhood Hits	822	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

GLP1R_MOUSE
NC score	0.003637 (rank : 171)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	184	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

WNK1_MOUSE
NC score	0.003480 (rank : 172)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	184	Target Neighborhood Hits	1179	Shared Neighborhood Hits	39
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

TMPSD_MOUSE
NC score	0.003219 (rank : 173)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	184	Target Neighborhood Hits	334	Shared Neighborhood Hits	19
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

KIF11_HUMAN
NC score	0.002750 (rank : 174)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	184	Target Neighborhood Hits	583	Shared Neighborhood Hits	8
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

TMPSD_HUMAN
NC score	0.002735 (rank : 175)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	184	Target Neighborhood Hits	333	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ERBB2_MOUSE
NC score	0.002644 (rank : 176)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	184	Target Neighborhood Hits	918	Shared Neighborhood Hits	15
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

MYLK2_HUMAN
NC score	0.001465 (rank : 177)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	184	Target Neighborhood Hits	920	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

DUET_HUMAN
NC score	0.001219 (rank : 178)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	184	Target Neighborhood Hits	1220	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ZN592_MOUSE
NC score	0.000665 (rank : 179)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	184	Target Neighborhood Hits	768	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

PCDGJ_HUMAN
NC score	0.000145 (rank : 180)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	184	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5F8, Q9UN63	Gene names	PCDHGB7
Domain Architecture
Description	Protocadherin gamma B7 precursor (PCDH-gamma-B7).

ZN406_MOUSE
NC score	0.000062 (rank : 181)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	184	Target Neighborhood Hits	800	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.

ROR2_HUMAN
NC score	-0.000791 (rank : 182)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	184	Target Neighborhood Hits	1014	Shared Neighborhood Hits	10
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

E2AK2_MOUSE
NC score	-0.001198 (rank : 183)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	184	Target Neighborhood Hits	864	Shared Neighborhood Hits	11
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

ADA2A_MOUSE
NC score	-0.001218 (rank : 184)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	184	Target Neighborhood Hits	900	Shared Neighborhood Hits	6
SwissProt Accessions	Q01338	Gene names	Adra2a
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR).

ZN524_MOUSE
NC score	-0.001598 (rank : 185)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	184	Target Neighborhood Hits	712	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0B1, Q9DCQ0	Gene names	Znf524, Zfp524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.