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Network neighborhood for query Sequence : JHD2A_HUMAN

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JHD2A_HUMAN
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

JHD2A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2A_MOUSE
θ value	0 (rank : 2)	NC score	0.983812 (rank : 2)
Query Neighborhood Hits	118	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2B_HUMAN
θ value	0 (rank : 3)	NC score	0.957381 (rank : 4)
Query Neighborhood Hits	118	Target Neighborhood Hits	171	Shared Neighborhood Hits	19
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

JHD2B_MOUSE
θ value	0 (rank : 4)	NC score	0.964883 (rank : 3)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

JHD2C_HUMAN
θ value	0 (rank : 5)	NC score	0.916314 (rank : 6)
Query Neighborhood Hits	118	Target Neighborhood Hits	279	Shared Neighborhood Hits	23
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

JHD2C_MOUSE
θ value	0 (rank : 6)	NC score	0.921424 (rank : 5)
Query Neighborhood Hits	118	Target Neighborhood Hits	297	Shared Neighborhood Hits	20
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

HAIR_HUMAN
θ value	8.00737e-57 (rank : 7)	NC score	0.771658 (rank : 8)
Query Neighborhood Hits	118	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

HAIR_MOUSE
θ value	2.76489e-41 (rank : 8)	NC score	0.774358 (rank : 7)
Query Neighborhood Hits	118	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

SRRM2_HUMAN
θ value	0.00390308 (rank : 9)	NC score	0.081326 (rank : 10)
Query Neighborhood Hits	118	Target Neighborhood Hits	1296	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

APC_MOUSE
θ value	0.00509761 (rank : 10)	NC score	0.078662 (rank : 11)
Query Neighborhood Hits	118	Target Neighborhood Hits	441	Shared Neighborhood Hits	21
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

NFH_MOUSE
θ value	0.0148317 (rank : 11)	NC score	0.037559 (rank : 33)
Query Neighborhood Hits	118	Target Neighborhood Hits	2247	Shared Neighborhood Hits	65
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NFH_HUMAN
θ value	0.0431538 (rank : 12)	NC score	0.033958 (rank : 38)
Query Neighborhood Hits	118	Target Neighborhood Hits	1242	Shared Neighborhood Hits	44
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GTSE1_HUMAN
θ value	0.0736092 (rank : 13)	NC score	0.055194 (rank : 15)
Query Neighborhood Hits	118	Target Neighborhood Hits	193	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

REXO1_HUMAN
θ value	0.0736092 (rank : 14)	NC score	0.049946 (rank : 20)
Query Neighborhood Hits	118	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

MTMR7_MOUSE
θ value	0.0961366 (rank : 15)	NC score	0.028901 (rank : 46)
Query Neighborhood Hits	118	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

JPH2_MOUSE
θ value	0.125558 (rank : 16)	NC score	0.030615 (rank : 44)
Query Neighborhood Hits	118	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MCR_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.028655 (rank : 48)
Query Neighborhood Hits	118	Target Neighborhood Hits	149	Shared Neighborhood Hits	10
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

ALG9_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.060303 (rank : 12)
Query Neighborhood Hits	118	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H6U8, Q6ZMD5, Q7Z4R4, Q96GS7, Q96PB9, Q9H068	Gene names	ALG9, DIBD1
Domain Architecture	No domain graphic available
Description	Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.-) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1).

MTMR7_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.027368 (rank : 49)
Query Neighborhood Hits	118	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

ASPP2_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.018956 (rank : 65)
Query Neighborhood Hits	118	Target Neighborhood Hits	1156	Shared Neighborhood Hits	31
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

MAP4_MOUSE
θ value	0.279714 (rank : 21)	NC score	0.042012 (rank : 26)
Query Neighborhood Hits	118	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RTP3_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.044846 (rank : 23)
Query Neighborhood Hits	118	Target Neighborhood Hits	374	Shared Neighborhood Hits	27
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

HOMEZ_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.039768 (rank : 27)
Query Neighborhood Hits	118	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

NACAM_MOUSE
θ value	0.365318 (rank : 24)	NC score	0.044117 (rank : 24)
Query Neighborhood Hits	118	Target Neighborhood Hits	1866	Shared Neighborhood Hits	61
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ZCH10_MOUSE
θ value	0.365318 (rank : 25)	NC score	0.053159 (rank : 16)
Query Neighborhood Hits	118	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

APC_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.057486 (rank : 13)
Query Neighborhood Hits	118	Target Neighborhood Hits	603	Shared Neighborhood Hits	31
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PCLO_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.039191 (rank : 28)
Query Neighborhood Hits	118	Target Neighborhood Hits	2275	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ZFP37_MOUSE
θ value	0.47712 (rank : 28)	NC score	0.002817 (rank : 115)
Query Neighborhood Hits	118	Target Neighborhood Hits	906	Shared Neighborhood Hits	15
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ADM1B_MOUSE
θ value	0.62314 (rank : 29)	NC score	0.011301 (rank : 84)
Query Neighborhood Hits	118	Target Neighborhood Hits	236	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

AFF1_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.051505 (rank : 18)
Query Neighborhood Hits	118	Target Neighborhood Hits	506	Shared Neighborhood Hits	31
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CENPC_MOUSE
θ value	0.62314 (rank : 31)	NC score	0.039190 (rank : 29)
Query Neighborhood Hits	118	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

SRRM2_MOUSE
θ value	0.62314 (rank : 32)	NC score	0.087538 (rank : 9)
Query Neighborhood Hits	118	Target Neighborhood Hits	1470	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ALG9_MOUSE
θ value	0.813845 (rank : 33)	NC score	0.047404 (rank : 21)
Query Neighborhood Hits	118	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDI9, Q8BT44, Q8C378, Q8C7G0	Gene names	Alg9, Dibd1
Domain Architecture	No domain graphic available
Description	Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.-) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1 homolog).

NEB2_HUMAN
θ value	0.813845 (rank : 34)	NC score	0.012124 (rank : 83)
Query Neighborhood Hits	118	Target Neighborhood Hits	883	Shared Neighborhood Hits	10
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PO121_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.035335 (rank : 35)
Query Neighborhood Hits	118	Target Neighborhood Hits	344	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PRGR_MOUSE
θ value	0.813845 (rank : 36)	NC score	0.020803 (rank : 57)
Query Neighborhood Hits	118	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SASH1_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.034985 (rank : 36)
Query Neighborhood Hits	118	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

BTD_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.026097 (rank : 50)
Query Neighborhood Hits	118	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P43251, Q96EM9	Gene names	BTD
Domain Architecture
Description	Biotinidase precursor (EC 3.5.1.12).

CM007_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.025584 (rank : 51)
Query Neighborhood Hits	118	Target Neighborhood Hits	416	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

ZCH11_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.028895 (rank : 47)
Query Neighborhood Hits	118	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

DPP4_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.019234 (rank : 64)
Query Neighborhood Hits	118	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

EP300_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.024215 (rank : 55)
Query Neighborhood Hits	118	Target Neighborhood Hits	821	Shared Neighborhood Hits	29
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

NP1L3_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.034510 (rank : 37)
Query Neighborhood Hits	118	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

SYTL2_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.029056 (rank : 45)
Query Neighborhood Hits	118	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TITIN_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.006794 (rank : 104)
Query Neighborhood Hits	118	Target Neighborhood Hits	2923	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WDR79_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.013886 (rank : 78)
Query Neighborhood Hits	118	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

ZFY28_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.024703 (rank : 53)
Query Neighborhood Hits	118	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ENAM_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.030633 (rank : 43)
Query Neighborhood Hits	118	Target Neighborhood Hits	229	Shared Neighborhood Hits	15
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

MCR_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.024251 (rank : 54)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PCLO_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.031521 (rank : 42)
Query Neighborhood Hits	118	Target Neighborhood Hits	2046	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RP1L1_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.025106 (rank : 52)
Query Neighborhood Hits	118	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

CJ078_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.052941 (rank : 17)
Query Neighborhood Hits	118	Target Neighborhood Hits	559	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

IGHG1_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.008812 (rank : 96)
Query Neighborhood Hits	118	Target Neighborhood Hits	229	Shared Neighborhood Hits	4
SwissProt Accessions	P01857	Gene names	IGHG1
Domain Architecture
Description	Ig gamma-1 chain C region.

PRG4_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.037970 (rank : 32)
Query Neighborhood Hits	118	Target Neighborhood Hits	764	Shared Neighborhood Hits	30
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RB6I2_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.006219 (rank : 105)
Query Neighborhood Hits	118	Target Neighborhood Hits	1584	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

STON2_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.031687 (rank : 41)
Query Neighborhood Hits	118	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

UBQL4_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.014155 (rank : 77)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

DDX21_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.006217 (rank : 106)
Query Neighborhood Hits	118	Target Neighborhood Hits	308	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

IF4G1_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.016124 (rank : 72)
Query Neighborhood Hits	118	Target Neighborhood Hits	347	Shared Neighborhood Hits	13
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

NOL6_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.015421 (rank : 73)
Query Neighborhood Hits	118	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5K4, Q6PAN8, Q8C6V4, Q8R5K3, Q8VCG0, Q8WTY7	Gene names	Nol6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

SPEG_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.003485 (rank : 111)
Query Neighborhood Hits	118	Target Neighborhood Hits	1762	Shared Neighborhood Hits	28
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TCF20_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.038699 (rank : 31)
Query Neighborhood Hits	118	Target Neighborhood Hits	396	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TTBK2_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.009843 (rank : 89)
Query Neighborhood Hits	118	Target Neighborhood Hits	811	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

ZAN_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.021723 (rank : 56)
Query Neighborhood Hits	118	Target Neighborhood Hits	679	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ACINU_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.038716 (rank : 30)
Query Neighborhood Hits	118	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ARI1B_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.020253 (rank : 59)
Query Neighborhood Hits	118	Target Neighborhood Hits	567	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

BSND_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.018164 (rank : 69)
Query Neighborhood Hits	118	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VIM4, Q8C740, Q8CHY0	Gene names	Bsnd
Domain Architecture	No domain graphic available
Description	Barttin.

CM003_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.017278 (rank : 70)
Query Neighborhood Hits	118	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C263	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf3 homolog.

DNL1_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.018464 (rank : 67)
Query Neighborhood Hits	118	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

GCC2_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.004340 (rank : 110)
Query Neighborhood Hits	118	Target Neighborhood Hits	1619	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

IGHG2_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.007858 (rank : 101)
Query Neighborhood Hits	118	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	P01859	Gene names	IGHG2
Domain Architecture
Description	Ig gamma-2 chain C region.

MKRN1_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.009060 (rank : 92)
Query Neighborhood Hits	118	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

SDCB2_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.010406 (rank : 87)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SYNPO_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.018304 (rank : 68)
Query Neighborhood Hits	118	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TLN2_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.010099 (rank : 88)
Query Neighborhood Hits	118	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

ZC11A_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.019708 (rank : 61)
Query Neighborhood Hits	118	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

AFF4_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.045988 (rank : 22)
Query Neighborhood Hits	118	Target Neighborhood Hits	611	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AKAP6_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.014787 (rank : 74)
Query Neighborhood Hits	118	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

EEA1_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.003395 (rank : 113)
Query Neighborhood Hits	118	Target Neighborhood Hits	1637	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

LRC8C_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.003067 (rank : 114)
Query Neighborhood Hits	118	Target Neighborhood Hits	255	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDW0, Q9H075	Gene names	LRRC8C, AD158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

MAML1_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.014262 (rank : 75)
Query Neighborhood Hits	118	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MDC1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.035637 (rank : 34)
Query Neighborhood Hits	118	Target Neighborhood Hits	1446	Shared Neighborhood Hits	50
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYST4_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.018891 (rank : 66)
Query Neighborhood Hits	118	Target Neighborhood Hits	671	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

RIN2_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.012783 (rank : 81)
Query Neighborhood Hits	118	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

RSNL2_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.008979 (rank : 93)
Query Neighborhood Hits	118	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SGOL1_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.014194 (rank : 76)
Query Neighborhood Hits	118	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

SIP1_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.000780 (rank : 117)
Query Neighborhood Hits	118	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

TIMD4_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.013881 (rank : 79)
Query Neighborhood Hits	118	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

ANK2_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.019785 (rank : 60)
Query Neighborhood Hits	118	Target Neighborhood Hits	1615	Shared Neighborhood Hits	60
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

APTX_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.010997 (rank : 85)
Query Neighborhood Hits	118	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQC5, Q8BPA7, Q8C2B5, Q8K3D1, Q9CQ59	Gene names	Aptx
Domain Architecture
Description	Aprataxin homolog (Forkhead-associated domain histidine triad-like protein) (FHA-HIT).

BGAL_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.009283 (rank : 91)
Query Neighborhood Hits	118	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P23780	Gene names	Glb1, Bgl, Glb-1
Domain Architecture
Description	Beta-galactosidase precursor (EC 3.2.1.23) (Lactase) (Acid beta- galactosidase).

GAK_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.003436 (rank : 112)
Query Neighborhood Hits	118	Target Neighborhood Hits	1028	Shared Neighborhood Hits	13
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

HEMGN_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.057322 (rank : 14)
Query Neighborhood Hits	118	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

NED4L_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.005839 (rank : 107)
Query Neighborhood Hits	118	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.005727 (rank : 108)
Query Neighborhood Hits	118	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NFAC1_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.007632 (rank : 102)
Query Neighborhood Hits	118	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NFAT5_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.008688 (rank : 98)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

PHC2_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.009831 (rank : 90)
Query Neighborhood Hits	118	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PP4R1_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.008977 (rank : 94)
Query Neighborhood Hits	118	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

SC24A_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.043018 (rank : 25)
Query Neighborhood Hits	118	Target Neighborhood Hits	394	Shared Neighborhood Hits	21
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SGIP1_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.019550 (rank : 62)
Query Neighborhood Hits	118	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SIP1_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.000595 (rank : 118)
Query Neighborhood Hits	118	Target Neighborhood Hits	870	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

TCF20_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.032755 (rank : 39)
Query Neighborhood Hits	118	Target Neighborhood Hits	323	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

UBP42_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.008768 (rank : 97)
Query Neighborhood Hits	118	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBQL4_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.012866 (rank : 80)
Query Neighborhood Hits	118	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

ACINU_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.019459 (rank : 63)
Query Neighborhood Hits	118	Target Neighborhood Hits	712	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

COA2_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.012322 (rank : 82)
Query Neighborhood Hits	118	Target Neighborhood Hits	184	Shared Neighborhood Hits	14
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

IASPP_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.008430 (rank : 99)
Query Neighborhood Hits	118	Target Neighborhood Hits	688	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LPIN3_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.005689 (rank : 109)
Query Neighborhood Hits	118	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

M3K2_MOUSE
θ value	8.99809 (rank : 110)	NC score	-0.001472 (rank : 119)
Query Neighborhood Hits	118	Target Neighborhood Hits	846	Shared Neighborhood Hits	6
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

MYCL1_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.007522 (rank : 103)
Query Neighborhood Hits	118	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NC6IP_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.008937 (rank : 95)
Query Neighborhood Hits	118	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

PRAX_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.020385 (rank : 58)
Query Neighborhood Hits	118	Target Neighborhood Hits	199	Shared Neighborhood Hits	15
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PRELP_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.001264 (rank : 116)
Query Neighborhood Hits	118	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JK53	Gene names	Prelp
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

RAPH1_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.016277 (rank : 71)
Query Neighborhood Hits	118	Target Neighborhood Hits	593	Shared Neighborhood Hits	27
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RIN2_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.010885 (rank : 86)
Query Neighborhood Hits	118	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

SASH1_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.032482 (rank : 40)
Query Neighborhood Hits	118	Target Neighborhood Hits	292	Shared Neighborhood Hits	10
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

TLN2_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.008192 (rank : 100)
Query Neighborhood Hits	118	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

VCY1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.050811 (rank : 19)
Query Neighborhood Hits	118	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

Hits sorted by NC score

JHD2A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2A_MOUSE
NC score	0.983812 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	118	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2B_MOUSE
NC score	0.964883 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	118	Target Neighborhood Hits	115	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

JHD2B_HUMAN
NC score	0.957381 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	118	Target Neighborhood Hits	171	Shared Neighborhood Hits	19
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

JHD2C_MOUSE
NC score	0.921424 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	118	Target Neighborhood Hits	297	Shared Neighborhood Hits	20
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

JHD2C_HUMAN
NC score	0.916314 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	118	Target Neighborhood Hits	279	Shared Neighborhood Hits	23
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

HAIR_MOUSE
NC score	0.774358 (rank : 7)	θ value	2.76489e-41 (rank : 8)
Query Neighborhood Hits	118	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

HAIR_HUMAN
NC score	0.771658 (rank : 8)	θ value	8.00737e-57 (rank : 7)
Query Neighborhood Hits	118	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

SRRM2_MOUSE
NC score	0.087538 (rank : 9)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	118	Target Neighborhood Hits	1470	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM2_HUMAN
NC score	0.081326 (rank : 10)	θ value	0.00390308 (rank : 9)
Query Neighborhood Hits	118	Target Neighborhood Hits	1296	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

APC_MOUSE
NC score	0.078662 (rank : 11)	θ value	0.00509761 (rank : 10)
Query Neighborhood Hits	118	Target Neighborhood Hits	441	Shared Neighborhood Hits	21
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ALG9_HUMAN
NC score	0.060303 (rank : 12)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	118	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H6U8, Q6ZMD5, Q7Z4R4, Q96GS7, Q96PB9, Q9H068	Gene names	ALG9, DIBD1
Domain Architecture	No domain graphic available
Description	Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.-) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1).

APC_HUMAN
NC score	0.057486 (rank : 13)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	118	Target Neighborhood Hits	603	Shared Neighborhood Hits	31
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

HEMGN_MOUSE
NC score	0.057322 (rank : 14)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	118	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

GTSE1_HUMAN
NC score	0.055194 (rank : 15)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	118	Target Neighborhood Hits	193	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

ZCH10_MOUSE
NC score	0.053159 (rank : 16)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	118	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

CJ078_MOUSE
NC score	0.052941 (rank : 17)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	118	Target Neighborhood Hits	559	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

AFF1_HUMAN
NC score	0.051505 (rank : 18)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	118	Target Neighborhood Hits	506	Shared Neighborhood Hits	31
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

VCY1_HUMAN
NC score	0.050811 (rank : 19)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	118	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

REXO1_HUMAN
NC score	0.049946 (rank : 20)	θ value	0.0736092 (rank : 14)
Query Neighborhood Hits	118	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

ALG9_MOUSE
NC score	0.047404 (rank : 21)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	118	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDI9, Q8BT44, Q8C378, Q8C7G0	Gene names	Alg9, Dibd1
Domain Architecture	No domain graphic available
Description	Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.-) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1 homolog).

AFF4_HUMAN
NC score	0.045988 (rank : 22)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	118	Target Neighborhood Hits	611	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

RTP3_MOUSE
NC score	0.044846 (rank : 23)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	118	Target Neighborhood Hits	374	Shared Neighborhood Hits	27
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

NACAM_MOUSE
NC score	0.044117 (rank : 24)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	118	Target Neighborhood Hits	1866	Shared Neighborhood Hits	61
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SC24A_MOUSE
NC score	0.043018 (rank : 25)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	118	Target Neighborhood Hits	394	Shared Neighborhood Hits	21
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

MAP4_MOUSE
NC score	0.042012 (rank : 26)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	118	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

HOMEZ_HUMAN
NC score	0.039768 (rank : 27)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	118	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

PCLO_MOUSE
NC score	0.039191 (rank : 28)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	118	Target Neighborhood Hits	2275	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CENPC_MOUSE
NC score	0.039190 (rank : 29)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	118	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

ACINU_HUMAN
NC score	0.038716 (rank : 30)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	118	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TCF20_MOUSE
NC score	0.038699 (rank : 31)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	118	Target Neighborhood Hits	396	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

PRG4_HUMAN
NC score	0.037970 (rank : 32)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	118	Target Neighborhood Hits	764	Shared Neighborhood Hits	30
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

NFH_MOUSE
NC score	0.037559 (rank : 33)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	118	Target Neighborhood Hits	2247	Shared Neighborhood Hits	65
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MDC1_HUMAN
NC score	0.035637 (rank : 34)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	118	Target Neighborhood Hits	1446	Shared Neighborhood Hits	50
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PO121_HUMAN
NC score	0.035335 (rank : 35)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	118	Target Neighborhood Hits	344	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SASH1_MOUSE
NC score	0.034985 (rank : 36)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	118	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

NP1L3_MOUSE
NC score	0.034510 (rank : 37)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	118	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

NFH_HUMAN
NC score	0.033958 (rank : 38)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	118	Target Neighborhood Hits	1242	Shared Neighborhood Hits	44
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TCF20_HUMAN
NC score	0.032755 (rank : 39)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	118	Target Neighborhood Hits	323	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

SASH1_HUMAN
NC score	0.032482 (rank : 40)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	118	Target Neighborhood Hits	292	Shared Neighborhood Hits	10
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

STON2_MOUSE
NC score	0.031687 (rank : 41)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	118	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

PCLO_HUMAN
NC score	0.031521 (rank : 42)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	118	Target Neighborhood Hits	2046	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ENAM_MOUSE
NC score	0.030633 (rank : 43)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	118	Target Neighborhood Hits	229	Shared Neighborhood Hits	15
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

JPH2_MOUSE
NC score	0.030615 (rank : 44)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	118	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SYTL2_HUMAN
NC score	0.029056 (rank : 45)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	118	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

MTMR7_MOUSE
NC score	0.028901 (rank : 46)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	118	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

ZCH11_HUMAN
NC score	0.028895 (rank : 47)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	118	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

MCR_HUMAN
NC score	0.028655 (rank : 48)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	118	Target Neighborhood Hits	149	Shared Neighborhood Hits	10
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

MTMR7_HUMAN
NC score	0.027368 (rank : 49)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	118	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

BTD_HUMAN
NC score	0.026097 (rank : 50)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	118	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P43251, Q96EM9	Gene names	BTD
Domain Architecture
Description	Biotinidase precursor (EC 3.5.1.12).

CM007_MOUSE
NC score	0.025584 (rank : 51)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	118	Target Neighborhood Hits	416	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RP1L1_MOUSE
NC score	0.025106 (rank : 52)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	118	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

ZFY28_HUMAN
NC score	0.024703 (rank : 53)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	118	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

MCR_MOUSE
NC score	0.024251 (rank : 54)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

EP300_HUMAN
NC score	0.024215 (rank : 55)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	118	Target Neighborhood Hits	821	Shared Neighborhood Hits	29
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ZAN_HUMAN
NC score	0.021723 (rank : 56)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	118	Target Neighborhood Hits	679	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

PRGR_MOUSE
NC score	0.020803 (rank : 57)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	118	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

PRAX_MOUSE
NC score	0.020385 (rank : 58)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	118	Target Neighborhood Hits	199	Shared Neighborhood Hits	15
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

ARI1B_HUMAN
NC score	0.020253 (rank : 59)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	118	Target Neighborhood Hits	567	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ANK2_HUMAN
NC score	0.019785 (rank : 60)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	118	Target Neighborhood Hits	1615	Shared Neighborhood Hits	60
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ZC11A_HUMAN
NC score	0.019708 (rank : 61)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	118	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

SGIP1_HUMAN
NC score	0.019550 (rank : 62)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	118	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

ACINU_MOUSE
NC score	0.019459 (rank : 63)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	118	Target Neighborhood Hits	712	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

DPP4_MOUSE
NC score	0.019234 (rank : 64)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	118	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

ASPP2_HUMAN
NC score	0.018956 (rank : 65)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	118	Target Neighborhood Hits	1156	Shared Neighborhood Hits	31
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

MYST4_HUMAN
NC score	0.018891 (rank : 66)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	118	Target Neighborhood Hits	671	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

DNL1_HUMAN
NC score	0.018464 (rank : 67)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	118	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

SYNPO_MOUSE
NC score	0.018304 (rank : 68)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	118	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

BSND_MOUSE
NC score	0.018164 (rank : 69)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	118	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VIM4, Q8C740, Q8CHY0	Gene names	Bsnd
Domain Architecture	No domain graphic available
Description	Barttin.

CM003_MOUSE
NC score	0.017278 (rank : 70)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	118	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C263	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf3 homolog.

RAPH1_HUMAN
NC score	0.016277 (rank : 71)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	118	Target Neighborhood Hits	593	Shared Neighborhood Hits	27
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

IF4G1_HUMAN
NC score	0.016124 (rank : 72)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	118	Target Neighborhood Hits	347	Shared Neighborhood Hits	13
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

NOL6_MOUSE
NC score	0.015421 (rank : 73)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	118	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5K4, Q6PAN8, Q8C6V4, Q8R5K3, Q8VCG0, Q8WTY7	Gene names	Nol6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

AKAP6_HUMAN
NC score	0.014787 (rank : 74)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	118	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

MAML1_HUMAN
NC score	0.014262 (rank : 75)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	118	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SGOL1_HUMAN
NC score	0.014194 (rank : 76)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	118	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

UBQL4_MOUSE
NC score	0.014155 (rank : 77)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

WDR79_MOUSE
NC score	0.013886 (rank : 78)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	118	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

TIMD4_MOUSE
NC score	0.013881 (rank : 79)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	118	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

UBQL4_HUMAN
NC score	0.012866 (rank : 80)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	118	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

RIN2_HUMAN
NC score	0.012783 (rank : 81)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	118	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

COA2_HUMAN
NC score	0.012322 (rank : 82)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	118	Target Neighborhood Hits	184	Shared Neighborhood Hits	14
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

NEB2_HUMAN
NC score	0.012124 (rank : 83)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	118	Target Neighborhood Hits	883	Shared Neighborhood Hits	10
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

ADM1B_MOUSE
NC score	0.011301 (rank : 84)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	118	Target Neighborhood Hits	236	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

APTX_MOUSE
NC score	0.010997 (rank : 85)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	118	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQC5, Q8BPA7, Q8C2B5, Q8K3D1, Q9CQ59	Gene names	Aptx
Domain Architecture
Description	Aprataxin homolog (Forkhead-associated domain histidine triad-like protein) (FHA-HIT).

RIN2_MOUSE
NC score	0.010885 (rank : 86)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	118	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

SDCB2_MOUSE
NC score	0.010406 (rank : 87)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

TLN2_MOUSE
NC score	0.010099 (rank : 88)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	118	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TTBK2_MOUSE
NC score	0.009843 (rank : 89)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	118	Target Neighborhood Hits	811	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

PHC2_MOUSE
NC score	0.009831 (rank : 90)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	118	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

BGAL_MOUSE
NC score	0.009283 (rank : 91)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	118	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P23780	Gene names	Glb1, Bgl, Glb-1
Domain Architecture
Description	Beta-galactosidase precursor (EC 3.2.1.23) (Lactase) (Acid beta- galactosidase).

MKRN1_MOUSE
NC score	0.009060 (rank : 92)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	118	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

RSNL2_MOUSE
NC score	0.008979 (rank : 93)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	118	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

PP4R1_HUMAN
NC score	0.008977 (rank : 94)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	118	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

NC6IP_HUMAN
NC score	0.008937 (rank : 95)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	118	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

IGHG1_HUMAN
NC score	0.008812 (rank : 96)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	118	Target Neighborhood Hits	229	Shared Neighborhood Hits	4
SwissProt Accessions	P01857	Gene names	IGHG1
Domain Architecture
Description	Ig gamma-1 chain C region.

UBP42_HUMAN
NC score	0.008768 (rank : 97)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	118	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

NFAT5_MOUSE
NC score	0.008688 (rank : 98)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

IASPP_HUMAN
NC score	0.008430 (rank : 99)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	118	Target Neighborhood Hits	688	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TLN2_HUMAN
NC score	0.008192 (rank : 100)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	118	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

IGHG2_HUMAN
NC score	0.007858 (rank : 101)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	118	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	P01859	Gene names	IGHG2
Domain Architecture
Description	Ig gamma-2 chain C region.

NFAC1_MOUSE
NC score	0.007632 (rank : 102)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	118	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

MYCL1_MOUSE
NC score	0.007522 (rank : 103)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	118	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

TITIN_HUMAN
NC score	0.006794 (rank : 104)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	118	Target Neighborhood Hits	2923	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

RB6I2_HUMAN
NC score	0.006219 (rank : 105)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	118	Target Neighborhood Hits	1584	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

DDX21_HUMAN
NC score	0.006217 (rank : 106)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	118	Target Neighborhood Hits	308	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

NED4L_HUMAN
NC score	0.005839 (rank : 107)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	118	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
NC score	0.005727 (rank : 108)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	118	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

LPIN3_MOUSE
NC score	0.005689 (rank : 109)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	118	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

GCC2_MOUSE
NC score	0.004340 (rank : 110)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	118	Target Neighborhood Hits	1619	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

SPEG_HUMAN
NC score	0.003485 (rank : 111)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	118	Target Neighborhood Hits	1762	Shared Neighborhood Hits	28
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

GAK_HUMAN
NC score	0.003436 (rank : 112)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	118	Target Neighborhood Hits	1028	Shared Neighborhood Hits	13
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

EEA1_MOUSE
NC score	0.003395 (rank : 113)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	118	Target Neighborhood Hits	1637	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

LRC8C_HUMAN
NC score	0.003067 (rank : 114)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	118	Target Neighborhood Hits	255	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDW0, Q9H075	Gene names	LRRC8C, AD158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

ZFP37_MOUSE
NC score	0.002817 (rank : 115)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	118	Target Neighborhood Hits	906	Shared Neighborhood Hits	15
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

PRELP_MOUSE
NC score	0.001264 (rank : 116)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	118	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JK53	Gene names	Prelp
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

SIP1_HUMAN
NC score	0.000780 (rank : 117)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	118	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

SIP1_MOUSE
NC score	0.000595 (rank : 118)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	118	Target Neighborhood Hits	870	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

M3K2_MOUSE
NC score	-0.001472 (rank : 119)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	118	Target Neighborhood Hits	846	Shared Neighborhood Hits	6
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).