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Network neighborhood for query Sequence : MCR_HUMAN

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MCR_HUMAN
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MCR_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	149
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

MCR_MOUSE
θ value	0 (rank : 2)	NC score	0.996691 (rank : 2)
Query Neighborhood Hits	149	Target Neighborhood Hits	162	Shared Neighborhood Hits	120
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

GCR_HUMAN
θ value	1.02419e-128 (rank : 3)	NC score	0.980879 (rank : 3)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

GCR_MOUSE
θ value	8.67031e-128 (rank : 4)	NC score	0.980082 (rank : 4)
Query Neighborhood Hits	149	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

PRGR_HUMAN
θ value	1.21265e-121 (rank : 5)	NC score	0.977066 (rank : 5)
Query Neighborhood Hits	149	Target Neighborhood Hits	163	Shared Neighborhood Hits	97
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PRGR_MOUSE
θ value	1.02657e-120 (rank : 6)	NC score	0.970660 (rank : 8)
Query Neighborhood Hits	149	Target Neighborhood Hits	286	Shared Neighborhood Hits	101
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

ANDR_MOUSE
θ value	6.24247e-110 (rank : 7)	NC score	0.976063 (rank : 7)
Query Neighborhood Hits	149	Target Neighborhood Hits	133	Shared Neighborhood Hits	97
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ANDR_HUMAN
θ value	3.42535e-108 (rank : 8)	NC score	0.976646 (rank : 6)
Query Neighborhood Hits	149	Target Neighborhood Hits	126	Shared Neighborhood Hits	96
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ESR1_MOUSE
θ value	1.16164e-39 (rank : 9)	NC score	0.932814 (rank : 9)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR2_HUMAN
θ value	1.16164e-39 (rank : 10)	NC score	0.931086 (rank : 11)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR1_HUMAN
θ value	1.98146e-39 (rank : 11)	NC score	0.931569 (rank : 10)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ERR3_HUMAN
θ value	2.58786e-39 (rank : 12)	NC score	0.922638 (rank : 16)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	2.58786e-39 (rank : 13)	NC score	0.922638 (rank : 17)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ESR2_MOUSE
θ value	4.41421e-39 (rank : 14)	NC score	0.930842 (rank : 12)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ERR2_HUMAN
θ value	3.73686e-38 (rank : 15)	NC score	0.924644 (rank : 14)
Query Neighborhood Hits	149	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR2_MOUSE
θ value	2.42216e-37 (rank : 16)	NC score	0.924152 (rank : 15)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR1_HUMAN
θ value	4.568e-36 (rank : 17)	NC score	0.927724 (rank : 13)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	96
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

RARG1_HUMAN
θ value	3.62785e-25 (rank : 18)	NC score	0.876411 (rank : 46)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
θ value	3.62785e-25 (rank : 19)	NC score	0.875928 (rank : 49)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

NR2E3_MOUSE
θ value	4.73814e-25 (rank : 20)	NC score	0.888507 (rank : 19)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

RARG2_HUMAN
θ value	1.05554e-24 (rank : 21)	NC score	0.876256 (rank : 47)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
θ value	1.05554e-24 (rank : 22)	NC score	0.875963 (rank : 48)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

NR1H3_HUMAN
θ value	5.23862e-24 (rank : 23)	NC score	0.879070 (rank : 34)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR2E1_MOUSE
θ value	8.93572e-24 (rank : 24)	NC score	0.891177 (rank : 18)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E3_HUMAN
θ value	1.5242e-23 (rank : 25)	NC score	0.881230 (rank : 23)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

RXRB_HUMAN
θ value	1.5242e-23 (rank : 26)	NC score	0.874609 (rank : 51)
Query Neighborhood Hits	149	Target Neighborhood Hits	280	Shared Neighborhood Hits	104
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRB_MOUSE
θ value	1.5242e-23 (rank : 27)	NC score	0.876857 (rank : 44)
Query Neighborhood Hits	149	Target Neighborhood Hits	230	Shared Neighborhood Hits	104
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

RXRA_MOUSE
θ value	1.99067e-23 (rank : 28)	NC score	0.880550 (rank : 26)
Query Neighborhood Hits	149	Target Neighborhood Hits	129	Shared Neighborhood Hits	95
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

NR1H3_MOUSE
θ value	2.59989e-23 (rank : 29)	NC score	0.879185 (rank : 33)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

RXRA_HUMAN
θ value	2.59989e-23 (rank : 30)	NC score	0.877950 (rank : 37)
Query Neighborhood Hits	149	Target Neighborhood Hits	223	Shared Neighborhood Hits	100
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

COT1_HUMAN
θ value	4.43474e-23 (rank : 31)	NC score	0.871564 (rank : 61)
Query Neighborhood Hits	149	Target Neighborhood Hits	159	Shared Neighborhood Hits	94
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT1_MOUSE
θ value	4.43474e-23 (rank : 32)	NC score	0.871854 (rank : 58)
Query Neighborhood Hits	149	Target Neighborhood Hits	160	Shared Neighborhood Hits	94
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

NR1H4_HUMAN
θ value	4.43474e-23 (rank : 33)	NC score	0.882660 (rank : 21)
Query Neighborhood Hits	149	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

RARB_MOUSE
θ value	5.79196e-23 (rank : 34)	NC score	0.871790 (rank : 59)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

NR4A2_HUMAN
θ value	9.87957e-23 (rank : 35)	NC score	0.878890 (rank : 35)
Query Neighborhood Hits	149	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

RARA_HUMAN
θ value	9.87957e-23 (rank : 36)	NC score	0.872499 (rank : 55)
Query Neighborhood Hits	149	Target Neighborhood Hits	118	Shared Neighborhood Hits	95
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

NR2E1_HUMAN
θ value	1.29031e-22 (rank : 37)	NC score	0.888479 (rank : 20)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

RARA_MOUSE
θ value	1.29031e-22 (rank : 38)	NC score	0.872162 (rank : 57)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

HNF4A_HUMAN
θ value	1.6852e-22 (rank : 39)	NC score	0.879690 (rank : 31)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

NR4A2_MOUSE
θ value	2.20094e-22 (rank : 40)	NC score	0.878649 (rank : 36)
Query Neighborhood Hits	149	Target Neighborhood Hits	121	Shared Neighborhood Hits	96
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

THA_MOUSE
θ value	2.20094e-22 (rank : 41)	NC score	0.858770 (rank : 68)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

THA_HUMAN
θ value	2.87452e-22 (rank : 42)	NC score	0.858945 (rank : 67)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

NR4A3_MOUSE
θ value	4.9032e-22 (rank : 43)	NC score	0.880092 (rank : 29)
Query Neighborhood Hits	149	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

RARB_HUMAN
θ value	4.9032e-22 (rank : 44)	NC score	0.871744 (rank : 60)
Query Neighborhood Hits	149	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

NR4A3_HUMAN
θ value	8.36355e-22 (rank : 45)	NC score	0.880849 (rank : 25)
Query Neighborhood Hits	149	Target Neighborhood Hits	131	Shared Neighborhood Hits	95
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

COT2_HUMAN
θ value	1.09232e-21 (rank : 46)	NC score	0.873100 (rank : 52)
Query Neighborhood Hits	149	Target Neighborhood Hits	135	Shared Neighborhood Hits	95
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	1.09232e-21 (rank : 47)	NC score	0.873100 (rank : 53)
Query Neighborhood Hits	149	Target Neighborhood Hits	135	Shared Neighborhood Hits	95
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

NR1H4_MOUSE
θ value	1.09232e-21 (rank : 48)	NC score	0.880347 (rank : 27)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

EAR2_MOUSE
θ value	1.42661e-21 (rank : 49)	NC score	0.877125 (rank : 41)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

NR1H2_MOUSE
θ value	1.42661e-21 (rank : 50)	NC score	0.872632 (rank : 54)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

RXRG_MOUSE
θ value	1.42661e-21 (rank : 51)	NC score	0.880250 (rank : 28)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_HUMAN
θ value	2.43343e-21 (rank : 52)	NC score	0.877373 (rank : 40)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

HNF4G_HUMAN
θ value	5.42112e-21 (rank : 53)	NC score	0.881939 (rank : 22)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4G_MOUSE
θ value	7.0802e-21 (rank : 54)	NC score	0.881225 (rank : 24)
Query Neighborhood Hits	149	Target Neighborhood Hits	101	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

NR5A2_HUMAN
θ value	1.2077e-20 (rank : 55)	NC score	0.868205 (rank : 64)
Query Neighborhood Hits	149	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR5A2_MOUSE
θ value	1.5773e-20 (rank : 56)	NC score	0.870673 (rank : 63)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR1H2_HUMAN
θ value	2.06002e-20 (rank : 57)	NC score	0.867108 (rank : 65)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

HNF4A_MOUSE
θ value	3.51386e-20 (rank : 58)	NC score	0.879749 (rank : 30)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

EAR2_HUMAN
θ value	7.82807e-20 (rank : 59)	NC score	0.876880 (rank : 43)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

STF1_HUMAN
θ value	2.27762e-19 (rank : 60)	NC score	0.877598 (rank : 39)
Query Neighborhood Hits	149	Target Neighborhood Hits	132	Shared Neighborhood Hits	94
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
θ value	2.27762e-19 (rank : 61)	NC score	0.876764 (rank : 45)
Query Neighborhood Hits	149	Target Neighborhood Hits	137	Shared Neighborhood Hits	94
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

NR4A1_HUMAN
θ value	5.07402e-19 (rank : 62)	NC score	0.879446 (rank : 32)
Query Neighborhood Hits	149	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

THB1_MOUSE
θ value	6.62687e-19 (rank : 63)	NC score	0.846933 (rank : 85)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
θ value	1.47631e-18 (rank : 64)	NC score	0.847230 (rank : 83)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THB2_HUMAN
θ value	1.92812e-18 (rank : 65)	NC score	0.849332 (rank : 75)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
θ value	2.5182e-18 (rank : 66)	NC score	0.846993 (rank : 84)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

NR4A1_MOUSE
θ value	7.32683e-18 (rank : 67)	NC score	0.877699 (rank : 38)
Query Neighborhood Hits	149	Target Neighborhood Hits	128	Shared Neighborhood Hits	95
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

TR4_HUMAN
θ value	7.32683e-18 (rank : 68)	NC score	0.848760 (rank : 79)
Query Neighborhood Hits	149	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

PXR_MOUSE
θ value	9.56915e-18 (rank : 69)	NC score	0.856753 (rank : 69)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

TR2_MOUSE
θ value	9.56915e-18 (rank : 70)	NC score	0.852471 (rank : 70)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

TR2_HUMAN
θ value	1.24977e-17 (rank : 71)	NC score	0.865608 (rank : 66)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

TR4_MOUSE
θ value	1.63225e-17 (rank : 72)	NC score	0.848371 (rank : 80)
Query Neighborhood Hits	149	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

RORA_MOUSE
θ value	2.13179e-17 (rank : 73)	NC score	0.847677 (rank : 82)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORB_HUMAN
θ value	2.13179e-17 (rank : 74)	NC score	0.848984 (rank : 77)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	2.13179e-17 (rank : 75)	NC score	0.849132 (rank : 76)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORA_HUMAN
θ value	2.7842e-17 (rank : 76)	NC score	0.848983 (rank : 78)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

NR6A1_HUMAN
θ value	3.07829e-16 (rank : 77)	NC score	0.872392 (rank : 56)
Query Neighborhood Hits	149	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
θ value	3.07829e-16 (rank : 78)	NC score	0.871473 (rank : 62)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

RORG_MOUSE
θ value	5.25075e-16 (rank : 79)	NC score	0.847920 (rank : 81)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORG_HUMAN
θ value	6.85773e-16 (rank : 80)	NC score	0.843097 (rank : 86)
Query Neighborhood Hits	149	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

PXR_HUMAN
θ value	2.60593e-15 (rank : 81)	NC score	0.850945 (rank : 73)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

NR1I3_HUMAN
θ value	4.44505e-15 (rank : 82)	NC score	0.875920 (rank : 50)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

NR1I3_MOUSE
θ value	9.90251e-15 (rank : 83)	NC score	0.876907 (rank : 42)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

PPARG_HUMAN
θ value	1.68911e-14 (rank : 84)	NC score	0.836550 (rank : 91)
Query Neighborhood Hits	149	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARA_HUMAN
θ value	4.91457e-14 (rank : 85)	NC score	0.838893 (rank : 89)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARG_MOUSE
θ value	4.91457e-14 (rank : 86)	NC score	0.835493 (rank : 92)
Query Neighborhood Hits	149	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARD_HUMAN
θ value	1.42992e-13 (rank : 87)	NC score	0.832492 (rank : 93)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARD_MOUSE
θ value	1.86753e-13 (rank : 88)	NC score	0.829718 (rank : 94)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

VDR_HUMAN
θ value	3.18553e-13 (rank : 89)	NC score	0.850794 (rank : 74)
Query Neighborhood Hits	149	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_MOUSE
θ value	3.18553e-13 (rank : 90)	NC score	0.852145 (rank : 71)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

PPARA_MOUSE
θ value	5.43371e-13 (rank : 91)	NC score	0.837622 (rank : 90)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

NR1D1_HUMAN
θ value	7.09661e-13 (rank : 92)	NC score	0.851756 (rank : 72)
Query Neighborhood Hits	149	Target Neighborhood Hits	140	Shared Neighborhood Hits	98
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

NR1D2_HUMAN
θ value	1.58096e-12 (rank : 93)	NC score	0.842978 (rank : 87)
Query Neighborhood Hits	149	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1D2_MOUSE
θ value	1.58096e-12 (rank : 94)	NC score	0.840487 (rank : 88)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

NACAM_MOUSE
θ value	0.00390308 (rank : 95)	NC score	0.030805 (rank : 100)
Query Neighborhood Hits	149	Target Neighborhood Hits	1866	Shared Neighborhood Hits	36
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TAF9_MOUSE
θ value	0.0252991 (rank : 96)	NC score	0.029998 (rank : 101)
Query Neighborhood Hits	149	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

ANK2_HUMAN
θ value	0.0736092 (rank : 97)	NC score	0.004963 (rank : 135)
Query Neighborhood Hits	149	Target Neighborhood Hits	1615	Shared Neighborhood Hits	21
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

JHD2A_MOUSE
θ value	0.0736092 (rank : 98)	NC score	0.027906 (rank : 103)
Query Neighborhood Hits	149	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

NFH_MOUSE
θ value	0.0961366 (rank : 99)	NC score	0.003873 (rank : 138)
Query Neighborhood Hits	149	Target Neighborhood Hits	2247	Shared Neighborhood Hits	31
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GPR64_HUMAN
θ value	0.125558 (rank : 100)	NC score	0.012040 (rank : 120)
Query Neighborhood Hits	149	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

JHD2A_HUMAN
θ value	0.163984 (rank : 101)	NC score	0.028655 (rank : 102)
Query Neighborhood Hits	149	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

RAI1_HUMAN
θ value	0.365318 (rank : 102)	NC score	0.023917 (rank : 106)
Query Neighborhood Hits	149	Target Neighborhood Hits	360	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CJ078_MOUSE
θ value	0.47712 (rank : 103)	NC score	0.019120 (rank : 109)
Query Neighborhood Hits	149	Target Neighborhood Hits	559	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

IL4RA_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.026295 (rank : 104)
Query Neighborhood Hits	149	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

E2F3_MOUSE
θ value	0.62314 (rank : 105)	NC score	0.019191 (rank : 108)
Query Neighborhood Hits	149	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

MUC1_MOUSE
θ value	0.62314 (rank : 106)	NC score	0.034357 (rank : 99)
Query Neighborhood Hits	149	Target Neighborhood Hits	388	Shared Neighborhood Hits	23
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

RAI1_MOUSE
θ value	0.62314 (rank : 107)	NC score	0.026156 (rank : 105)
Query Neighborhood Hits	149	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

T106A_MOUSE
θ value	0.62314 (rank : 108)	NC score	0.023301 (rank : 107)
Query Neighborhood Hits	149	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VC04, Q3U4J0, Q3U9D3, Q3UEA5, Q8CIC3	Gene names	Tmem106a
Domain Architecture	No domain graphic available
Description	Transmembrane protein 106A.

CTND2_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.011272 (rank : 121)
Query Neighborhood Hits	149	Target Neighborhood Hits	333	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

NCOA1_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.012047 (rank : 119)
Query Neighborhood Hits	149	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NU153_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.018470 (rank : 111)
Query Neighborhood Hits	149	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

MYOTI_MOUSE
θ value	1.38821 (rank : 112)	NC score	0.005101 (rank : 134)
Query Neighborhood Hits	149	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

ZNF31_HUMAN
θ value	1.38821 (rank : 113)	NC score	-0.007333 (rank : 152)
Query Neighborhood Hits	149	Target Neighborhood Hits	769	Shared Neighborhood Hits	3
SwissProt Accessions	P17040, Q96H84	Gene names	ZNF31, KOX29, ZNF360, ZSCAN20
Domain Architecture	No domain graphic available
Description	Zinc finger protein 31 (Zinc finger protein KOX29) (Zinc finger and SCAN domain-containing protein 20) (Zinc finger protein 360).

E2F3_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.016078 (rank : 114)
Query Neighborhood Hits	149	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

DUS1_HUMAN
θ value	2.36792 (rank : 115)	NC score	0.003173 (rank : 140)
Query Neighborhood Hits	149	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

ETV5_MOUSE
θ value	2.36792 (rank : 116)	NC score	0.011209 (rank : 122)
Query Neighborhood Hits	149	Target Neighborhood Hits	328	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

RGS3_MOUSE
θ value	2.36792 (rank : 117)	NC score	0.007127 (rank : 130)
Query Neighborhood Hits	149	Target Neighborhood Hits	1621	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CTND2_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.010969 (rank : 124)
Query Neighborhood Hits	149	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

HSF1_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.010133 (rank : 125)
Query Neighborhood Hits	149	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

NCOA2_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.014735 (rank : 115)
Query Neighborhood Hits	149	Target Neighborhood Hits	281	Shared Neighborhood Hits	15
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PER3_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.014722 (rank : 116)
Query Neighborhood Hits	149	Target Neighborhood Hits	479	Shared Neighborhood Hits	21
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PTPRJ_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.000378 (rank : 146)
Query Neighborhood Hits	149	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

ARI1A_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.009840 (rank : 127)
Query Neighborhood Hits	149	Target Neighborhood Hits	787	Shared Neighborhood Hits	25
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CREB1_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.007394 (rank : 129)
Query Neighborhood Hits	149	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

MAML3_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.014026 (rank : 117)
Query Neighborhood Hits	149	Target Neighborhood Hits	323	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

NCOA6_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.017135 (rank : 112)
Query Neighborhood Hits	149	Target Neighborhood Hits	1202	Shared Neighborhood Hits	34
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

OTP_MOUSE
θ value	4.03905 (rank : 127)	NC score	-0.001085 (rank : 148)
Query Neighborhood Hits	149	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

DCC_MOUSE
θ value	5.27518 (rank : 128)	NC score	-0.003165 (rank : 151)
Query Neighborhood Hits	149	Target Neighborhood Hits	896	Shared Neighborhood Hits	15
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DMRTC_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.009914 (rank : 126)
Query Neighborhood Hits	149	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q5HYR2, Q5HYR0, Q5U5K2, Q8N6L3, Q96SD3	Gene names	DMRTC1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1.

LRP2_HUMAN
θ value	5.27518 (rank : 130)	NC score	-0.002834 (rank : 150)
Query Neighborhood Hits	149	Target Neighborhood Hits	573	Shared Neighborhood Hits	3
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

MUCEN_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.011060 (rank : 123)
Query Neighborhood Hits	149	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

TCF8_HUMAN
θ value	5.27518 (rank : 132)	NC score	-0.007771 (rank : 153)
Query Neighborhood Hits	149	Target Neighborhood Hits	1057	Shared Neighborhood Hits	4
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TNR6A_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.016478 (rank : 113)
Query Neighborhood Hits	149	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

BAZ2A_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.000876 (rank : 144)
Query Neighborhood Hits	149	Target Neighborhood Hits	780	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

DDHD1_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.008564 (rank : 128)
Query Neighborhood Hits	149	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

ETV5_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.006260 (rank : 131)
Query Neighborhood Hits	149	Target Neighborhood Hits	181	Shared Neighborhood Hits	8
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

HDAC4_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.000317 (rank : 147)
Query Neighborhood Hits	149	Target Neighborhood Hits	390	Shared Neighborhood Hits	5
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

LIRA4_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.000511 (rank : 145)
Query Neighborhood Hits	149	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P59901	Gene names	LILRA4, ILT7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 4 precursor (Immunoglobulin-like transcript 7) (ILT-7) (CD85g antigen).

RIF1_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.002836 (rank : 141)
Query Neighborhood Hits	149	Target Neighborhood Hits	320	Shared Neighborhood Hits	4
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

SGIP1_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.012600 (rank : 118)
Query Neighborhood Hits	149	Target Neighborhood Hits	180	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SRRM2_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.004852 (rank : 137)
Query Neighborhood Hits	149	Target Neighborhood Hits	1470	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CREB1_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.005727 (rank : 132)
Query Neighborhood Hits	149	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

EPN3_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.002656 (rank : 142)
Query Neighborhood Hits	149	Target Neighborhood Hits	312	Shared Neighborhood Hits	11
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

NCOA6_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.019085 (rank : 110)
Query Neighborhood Hits	149	Target Neighborhood Hits	1076	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NFAC2_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.005494 (rank : 133)
Query Neighborhood Hits	149	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

SPY2_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.004921 (rank : 136)
Query Neighborhood Hits	149	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

STAM2_MOUSE
θ value	8.99809 (rank : 147)	NC score	-0.001500 (rank : 149)
Query Neighborhood Hits	149	Target Neighborhood Hits	285	Shared Neighborhood Hits	2
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

UBXD2_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.002120 (rank : 143)
Query Neighborhood Hits	149	Target Neighborhood Hits	241	Shared Neighborhood Hits	2
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

ZN638_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.003532 (rank : 139)
Query Neighborhood Hits	149	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

DAX1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.367362 (rank : 98)
Query Neighborhood Hits	149	Target Neighborhood Hits	65	Shared Neighborhood Hits	55
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

DAX1_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.391744 (rank : 97)
Query Neighborhood Hits	149	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

SHP_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.401191 (rank : 95)
Query Neighborhood Hits	149	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.396237 (rank : 96)
Query Neighborhood Hits	149	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

Hits sorted by NC score

MCR_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	149
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

MCR_MOUSE
NC score	0.996691 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	149	Target Neighborhood Hits	162	Shared Neighborhood Hits	120
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

GCR_HUMAN
NC score	0.980879 (rank : 3)	θ value	1.02419e-128 (rank : 3)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

GCR_MOUSE
NC score	0.980082 (rank : 4)	θ value	8.67031e-128 (rank : 4)
Query Neighborhood Hits	149	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

PRGR_HUMAN
NC score	0.977066 (rank : 5)	θ value	1.21265e-121 (rank : 5)
Query Neighborhood Hits	149	Target Neighborhood Hits	163	Shared Neighborhood Hits	97
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

ANDR_HUMAN
NC score	0.976646 (rank : 6)	θ value	3.42535e-108 (rank : 8)
Query Neighborhood Hits	149	Target Neighborhood Hits	126	Shared Neighborhood Hits	96
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ANDR_MOUSE
NC score	0.976063 (rank : 7)	θ value	6.24247e-110 (rank : 7)
Query Neighborhood Hits	149	Target Neighborhood Hits	133	Shared Neighborhood Hits	97
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

PRGR_MOUSE
NC score	0.970660 (rank : 8)	θ value	1.02657e-120 (rank : 6)
Query Neighborhood Hits	149	Target Neighborhood Hits	286	Shared Neighborhood Hits	101
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

ESR1_MOUSE
NC score	0.932814 (rank : 9)	θ value	1.16164e-39 (rank : 9)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_HUMAN
NC score	0.931569 (rank : 10)	θ value	1.98146e-39 (rank : 11)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR2_HUMAN
NC score	0.931086 (rank : 11)	θ value	1.16164e-39 (rank : 10)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR2_MOUSE
NC score	0.930842 (rank : 12)	θ value	4.41421e-39 (rank : 14)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ERR1_HUMAN
NC score	0.927724 (rank : 13)	θ value	4.568e-36 (rank : 17)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	96
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

ERR2_HUMAN
NC score	0.924644 (rank : 14)	θ value	3.73686e-38 (rank : 15)
Query Neighborhood Hits	149	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR2_MOUSE
NC score	0.924152 (rank : 15)	θ value	2.42216e-37 (rank : 16)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR3_HUMAN
NC score	0.922638 (rank : 16)	θ value	2.58786e-39 (rank : 12)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.922638 (rank : 17)	θ value	2.58786e-39 (rank : 13)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

NR2E1_MOUSE
NC score	0.891177 (rank : 18)	θ value	8.93572e-24 (rank : 24)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E3_MOUSE
NC score	0.888507 (rank : 19)	θ value	4.73814e-25 (rank : 20)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E1_HUMAN
NC score	0.888479 (rank : 20)	θ value	1.29031e-22 (rank : 37)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR1H4_HUMAN
NC score	0.882660 (rank : 21)	θ value	4.43474e-23 (rank : 33)
Query Neighborhood Hits	149	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

HNF4G_HUMAN
NC score	0.881939 (rank : 22)	θ value	5.42112e-21 (rank : 53)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

NR2E3_HUMAN
NC score	0.881230 (rank : 23)	θ value	1.5242e-23 (rank : 25)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

HNF4G_MOUSE
NC score	0.881225 (rank : 24)	θ value	7.0802e-21 (rank : 54)
Query Neighborhood Hits	149	Target Neighborhood Hits	101	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

NR4A3_HUMAN
NC score	0.880849 (rank : 25)	θ value	8.36355e-22 (rank : 45)
Query Neighborhood Hits	149	Target Neighborhood Hits	131	Shared Neighborhood Hits	95
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

RXRA_MOUSE
NC score	0.880550 (rank : 26)	θ value	1.99067e-23 (rank : 28)
Query Neighborhood Hits	149	Target Neighborhood Hits	129	Shared Neighborhood Hits	95
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

NR1H4_MOUSE
NC score	0.880347 (rank : 27)	θ value	1.09232e-21 (rank : 48)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

RXRG_MOUSE
NC score	0.880250 (rank : 28)	θ value	1.42661e-21 (rank : 51)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

NR4A3_MOUSE
NC score	0.880092 (rank : 29)	θ value	4.9032e-22 (rank : 43)
Query Neighborhood Hits	149	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

HNF4A_MOUSE
NC score	0.879749 (rank : 30)	θ value	3.51386e-20 (rank : 58)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_HUMAN
NC score	0.879690 (rank : 31)	θ value	1.6852e-22 (rank : 39)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

NR4A1_HUMAN
NC score	0.879446 (rank : 32)	θ value	5.07402e-19 (rank : 62)
Query Neighborhood Hits	149	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR1H3_MOUSE
NC score	0.879185 (rank : 33)	θ value	2.59989e-23 (rank : 29)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H3_HUMAN
NC score	0.879070 (rank : 34)	θ value	5.23862e-24 (rank : 23)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR4A2_HUMAN
NC score	0.878890 (rank : 35)	θ value	9.87957e-23 (rank : 35)
Query Neighborhood Hits	149	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
NC score	0.878649 (rank : 36)	θ value	2.20094e-22 (rank : 40)
Query Neighborhood Hits	149	Target Neighborhood Hits	121	Shared Neighborhood Hits	96
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

RXRA_HUMAN
NC score	0.877950 (rank : 37)	θ value	2.59989e-23 (rank : 30)
Query Neighborhood Hits	149	Target Neighborhood Hits	223	Shared Neighborhood Hits	100
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

NR4A1_MOUSE
NC score	0.877699 (rank : 38)	θ value	7.32683e-18 (rank : 67)
Query Neighborhood Hits	149	Target Neighborhood Hits	128	Shared Neighborhood Hits	95
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

STF1_HUMAN
NC score	0.877598 (rank : 39)	θ value	2.27762e-19 (rank : 60)
Query Neighborhood Hits	149	Target Neighborhood Hits	132	Shared Neighborhood Hits	94
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

RXRG_HUMAN
NC score	0.877373 (rank : 40)	θ value	2.43343e-21 (rank : 52)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

EAR2_MOUSE
NC score	0.877125 (rank : 41)	θ value	1.42661e-21 (rank : 49)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

NR1I3_MOUSE
NC score	0.876907 (rank : 42)	θ value	9.90251e-15 (rank : 83)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

EAR2_HUMAN
NC score	0.876880 (rank : 43)	θ value	7.82807e-20 (rank : 59)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

RXRB_MOUSE
NC score	0.876857 (rank : 44)	θ value	1.5242e-23 (rank : 27)
Query Neighborhood Hits	149	Target Neighborhood Hits	230	Shared Neighborhood Hits	104
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

STF1_MOUSE
NC score	0.876764 (rank : 45)	θ value	2.27762e-19 (rank : 61)
Query Neighborhood Hits	149	Target Neighborhood Hits	137	Shared Neighborhood Hits	94
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

RARG1_HUMAN
NC score	0.876411 (rank : 46)	θ value	3.62785e-25 (rank : 18)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_HUMAN
NC score	0.876256 (rank : 47)	θ value	1.05554e-24 (rank : 21)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
NC score	0.875963 (rank : 48)	θ value	1.05554e-24 (rank : 22)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARG1_MOUSE
NC score	0.875928 (rank : 49)	θ value	3.62785e-25 (rank : 19)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

NR1I3_HUMAN
NC score	0.875920 (rank : 50)	θ value	4.44505e-15 (rank : 82)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

RXRB_HUMAN
NC score	0.874609 (rank : 51)	θ value	1.5242e-23 (rank : 26)
Query Neighborhood Hits	149	Target Neighborhood Hits	280	Shared Neighborhood Hits	104
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

COT2_HUMAN
NC score	0.873100 (rank : 52)	θ value	1.09232e-21 (rank : 46)
Query Neighborhood Hits	149	Target Neighborhood Hits	135	Shared Neighborhood Hits	95
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.873100 (rank : 53)	θ value	1.09232e-21 (rank : 47)
Query Neighborhood Hits	149	Target Neighborhood Hits	135	Shared Neighborhood Hits	95
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

NR1H2_MOUSE
NC score	0.872632 (rank : 54)	θ value	1.42661e-21 (rank : 50)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

RARA_HUMAN
NC score	0.872499 (rank : 55)	θ value	9.87957e-23 (rank : 36)
Query Neighborhood Hits	149	Target Neighborhood Hits	118	Shared Neighborhood Hits	95
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

NR6A1_HUMAN
NC score	0.872392 (rank : 56)	θ value	3.07829e-16 (rank : 77)
Query Neighborhood Hits	149	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

RARA_MOUSE
NC score	0.872162 (rank : 57)	θ value	1.29031e-22 (rank : 38)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

COT1_MOUSE
NC score	0.871854 (rank : 58)	θ value	4.43474e-23 (rank : 32)
Query Neighborhood Hits	149	Target Neighborhood Hits	160	Shared Neighborhood Hits	94
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

RARB_MOUSE
NC score	0.871790 (rank : 59)	θ value	5.79196e-23 (rank : 34)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARB_HUMAN
NC score	0.871744 (rank : 60)	θ value	4.9032e-22 (rank : 44)
Query Neighborhood Hits	149	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

COT1_HUMAN
NC score	0.871564 (rank : 61)	θ value	4.43474e-23 (rank : 31)
Query Neighborhood Hits	149	Target Neighborhood Hits	159	Shared Neighborhood Hits	94
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

NR6A1_MOUSE
NC score	0.871473 (rank : 62)	θ value	3.07829e-16 (rank : 78)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR5A2_MOUSE
NC score	0.870673 (rank : 63)	θ value	1.5773e-20 (rank : 56)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR5A2_HUMAN
NC score	0.868205 (rank : 64)	θ value	1.2077e-20 (rank : 55)
Query Neighborhood Hits	149	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR1H2_HUMAN
NC score	0.867108 (rank : 65)	θ value	2.06002e-20 (rank : 57)
Query Neighborhood Hits	149	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

TR2_HUMAN
NC score	0.865608 (rank : 66)	θ value	1.24977e-17 (rank : 71)
Query Neighborhood Hits	149	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

THA_HUMAN
NC score	0.858945 (rank : 67)	θ value	2.87452e-22 (rank : 42)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
NC score	0.858770 (rank : 68)	θ value	2.20094e-22 (rank : 41)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

PXR_MOUSE
NC score	0.856753 (rank : 69)	θ value	9.56915e-18 (rank : 69)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

TR2_MOUSE
NC score	0.852471 (rank : 70)	θ value	9.56915e-18 (rank : 70)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

VDR_MOUSE
NC score	0.852145 (rank : 71)	θ value	3.18553e-13 (rank : 90)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

NR1D1_HUMAN
NC score	0.851756 (rank : 72)	θ value	7.09661e-13 (rank : 92)
Query Neighborhood Hits	149	Target Neighborhood Hits	140	Shared Neighborhood Hits	98
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

PXR_HUMAN
NC score	0.850945 (rank : 73)	θ value	2.60593e-15 (rank : 81)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

VDR_HUMAN
NC score	0.850794 (rank : 74)	θ value	3.18553e-13 (rank : 89)
Query Neighborhood Hits	149	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

THB2_HUMAN
NC score	0.849332 (rank : 75)	θ value	1.92812e-18 (rank : 65)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

RORB_MOUSE
NC score	0.849132 (rank : 76)	θ value	2.13179e-17 (rank : 75)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_HUMAN
NC score	0.848984 (rank : 77)	θ value	2.13179e-17 (rank : 74)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORA_HUMAN
NC score	0.848983 (rank : 78)	θ value	2.7842e-17 (rank : 76)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

TR4_HUMAN
NC score	0.848760 (rank : 79)	θ value	7.32683e-18 (rank : 68)
Query Neighborhood Hits	149	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
NC score	0.848371 (rank : 80)	θ value	1.63225e-17 (rank : 72)
Query Neighborhood Hits	149	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

RORG_MOUSE
NC score	0.847920 (rank : 81)	θ value	5.25075e-16 (rank : 79)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORA_MOUSE
NC score	0.847677 (rank : 82)	θ value	2.13179e-17 (rank : 73)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

THB2_MOUSE
NC score	0.847230 (rank : 83)	θ value	1.47631e-18 (rank : 64)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
NC score	0.846993 (rank : 84)	θ value	2.5182e-18 (rank : 66)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB1_MOUSE
NC score	0.846933 (rank : 85)	θ value	6.62687e-19 (rank : 63)
Query Neighborhood Hits	149	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

RORG_HUMAN
NC score	0.843097 (rank : 86)	θ value	6.85773e-16 (rank : 80)
Query Neighborhood Hits	149	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

NR1D2_HUMAN
NC score	0.842978 (rank : 87)	θ value	1.58096e-12 (rank : 93)
Query Neighborhood Hits	149	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1D2_MOUSE
NC score	0.840487 (rank : 88)	θ value	1.58096e-12 (rank : 94)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

PPARA_HUMAN
NC score	0.838893 (rank : 89)	θ value	4.91457e-14 (rank : 85)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARA_MOUSE
NC score	0.837622 (rank : 90)	θ value	5.43371e-13 (rank : 91)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARG_HUMAN
NC score	0.836550 (rank : 91)	θ value	1.68911e-14 (rank : 84)
Query Neighborhood Hits	149	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
NC score	0.835493 (rank : 92)	θ value	4.91457e-14 (rank : 86)
Query Neighborhood Hits	149	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARD_HUMAN
NC score	0.832492 (rank : 93)	θ value	1.42992e-13 (rank : 87)
Query Neighborhood Hits	149	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARD_MOUSE
NC score	0.829718 (rank : 94)	θ value	1.86753e-13 (rank : 88)
Query Neighborhood Hits	149	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

SHP_HUMAN
NC score	0.401191 (rank : 95)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	149	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
NC score	0.396237 (rank : 96)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	149	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
NC score	0.391744 (rank : 97)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	149	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

DAX1_HUMAN
NC score	0.367362 (rank : 98)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	149	Target Neighborhood Hits	65	Shared Neighborhood Hits	55
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

MUC1_MOUSE
NC score	0.034357 (rank : 99)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	149	Target Neighborhood Hits	388	Shared Neighborhood Hits	23
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NACAM_MOUSE
NC score	0.030805 (rank : 100)	θ value	0.00390308 (rank : 95)
Query Neighborhood Hits	149	Target Neighborhood Hits	1866	Shared Neighborhood Hits	36
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TAF9_MOUSE
NC score	0.029998 (rank : 101)	θ value	0.0252991 (rank : 96)
Query Neighborhood Hits	149	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

JHD2A_HUMAN
NC score	0.028655 (rank : 102)	θ value	0.163984 (rank : 101)
Query Neighborhood Hits	149	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2A_MOUSE
NC score	0.027906 (rank : 103)	θ value	0.0736092 (rank : 98)
Query Neighborhood Hits	149	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

IL4RA_HUMAN
NC score	0.026295 (rank : 104)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	149	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

RAI1_MOUSE
NC score	0.026156 (rank : 105)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	149	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_HUMAN
NC score	0.023917 (rank : 106)	θ value	0.365318 (rank : 102)
Query Neighborhood Hits	149	Target Neighborhood Hits	360	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

T106A_MOUSE
NC score	0.023301 (rank : 107)	θ value	0.62314 (rank : 108)
Query Neighborhood Hits	149	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VC04, Q3U4J0, Q3U9D3, Q3UEA5, Q8CIC3	Gene names	Tmem106a
Domain Architecture	No domain graphic available
Description	Transmembrane protein 106A.

E2F3_MOUSE
NC score	0.019191 (rank : 108)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	149	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

CJ078_MOUSE
NC score	0.019120 (rank : 109)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	149	Target Neighborhood Hits	559	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

NCOA6_MOUSE
NC score	0.019085 (rank : 110)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	149	Target Neighborhood Hits	1076	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NU153_HUMAN
NC score	0.018470 (rank : 111)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	149	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

NCOA6_HUMAN
NC score	0.017135 (rank : 112)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	149	Target Neighborhood Hits	1202	Shared Neighborhood Hits	34
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TNR6A_HUMAN
NC score	0.016478 (rank : 113)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	149	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

E2F3_HUMAN
NC score	0.016078 (rank : 114)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	149	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

NCOA2_HUMAN
NC score	0.014735 (rank : 115)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	149	Target Neighborhood Hits	281	Shared Neighborhood Hits	15
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PER3_HUMAN
NC score	0.014722 (rank : 116)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	149	Target Neighborhood Hits	479	Shared Neighborhood Hits	21
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

MAML3_HUMAN
NC score	0.014026 (rank : 117)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	149	Target Neighborhood Hits	323	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

SGIP1_MOUSE
NC score	0.012600 (rank : 118)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	149	Target Neighborhood Hits	180	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

NCOA1_HUMAN
NC score	0.012047 (rank : 119)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	149	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

GPR64_HUMAN
NC score	0.012040 (rank : 120)	θ value	0.125558 (rank : 100)
Query Neighborhood Hits	149	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

CTND2_HUMAN
NC score	0.011272 (rank : 121)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	149	Target Neighborhood Hits	333	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

ETV5_MOUSE
NC score	0.011209 (rank : 122)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	149	Target Neighborhood Hits	328	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

MUCEN_MOUSE
NC score	0.011060 (rank : 123)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	149	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

CTND2_MOUSE
NC score	0.010969 (rank : 124)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	149	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

HSF1_HUMAN
NC score	0.010133 (rank : 125)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	149	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

DMRTC_HUMAN
NC score	0.009914 (rank : 126)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	149	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q5HYR2, Q5HYR0, Q5U5K2, Q8N6L3, Q96SD3	Gene names	DMRTC1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1.

ARI1A_HUMAN
NC score	0.009840 (rank : 127)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	149	Target Neighborhood Hits	787	Shared Neighborhood Hits	25
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

DDHD1_HUMAN
NC score	0.008564 (rank : 128)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	149	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

CREB1_HUMAN
NC score	0.007394 (rank : 129)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	149	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

RGS3_MOUSE
NC score	0.007127 (rank : 130)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	149	Target Neighborhood Hits	1621	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ETV5_HUMAN
NC score	0.006260 (rank : 131)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	149	Target Neighborhood Hits	181	Shared Neighborhood Hits	8
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

CREB1_MOUSE
NC score	0.005727 (rank : 132)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	149	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

NFAC2_MOUSE
NC score	0.005494 (rank : 133)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	149	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

MYOTI_MOUSE
NC score	0.005101 (rank : 134)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	149	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

ANK2_HUMAN
NC score	0.004963 (rank : 135)	θ value	0.0736092 (rank : 97)
Query Neighborhood Hits	149	Target Neighborhood Hits	1615	Shared Neighborhood Hits	21
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

SPY2_HUMAN
NC score	0.004921 (rank : 136)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	149	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SRRM2_MOUSE
NC score	0.004852 (rank : 137)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	149	Target Neighborhood Hits	1470	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NFH_MOUSE
NC score	0.003873 (rank : 138)	θ value	0.0961366 (rank : 99)
Query Neighborhood Hits	149	Target Neighborhood Hits	2247	Shared Neighborhood Hits	31
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ZN638_HUMAN
NC score	0.003532 (rank : 139)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	149	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

DUS1_HUMAN
NC score	0.003173 (rank : 140)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	149	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

RIF1_HUMAN
NC score	0.002836 (rank : 141)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	149	Target Neighborhood Hits	320	Shared Neighborhood Hits	4
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

EPN3_MOUSE
NC score	0.002656 (rank : 142)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	149	Target Neighborhood Hits	312	Shared Neighborhood Hits	11
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

UBXD2_HUMAN
NC score	0.002120 (rank : 143)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	149	Target Neighborhood Hits	241	Shared Neighborhood Hits	2
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

BAZ2A_HUMAN
NC score	0.000876 (rank : 144)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	149	Target Neighborhood Hits	780	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

LIRA4_HUMAN
NC score	0.000511 (rank : 145)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	149	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P59901	Gene names	LILRA4, ILT7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 4 precursor (Immunoglobulin-like transcript 7) (ILT-7) (CD85g antigen).

PTPRJ_HUMAN
NC score	0.000378 (rank : 146)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	149	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

HDAC4_HUMAN
NC score	0.000317 (rank : 147)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	149	Target Neighborhood Hits	390	Shared Neighborhood Hits	5
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

OTP_MOUSE
NC score	-0.001085 (rank : 148)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	149	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

STAM2_MOUSE
NC score	-0.001500 (rank : 149)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	149	Target Neighborhood Hits	285	Shared Neighborhood Hits	2
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

LRP2_HUMAN
NC score	-0.002834 (rank : 150)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	149	Target Neighborhood Hits	573	Shared Neighborhood Hits	3
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

DCC_MOUSE
NC score	-0.003165 (rank : 151)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	149	Target Neighborhood Hits	896	Shared Neighborhood Hits	15
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ZNF31_HUMAN
NC score	-0.007333 (rank : 152)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	149	Target Neighborhood Hits	769	Shared Neighborhood Hits	3
SwissProt Accessions	P17040, Q96H84	Gene names	ZNF31, KOX29, ZNF360, ZSCAN20
Domain Architecture	No domain graphic available
Description	Zinc finger protein 31 (Zinc finger protein KOX29) (Zinc finger and SCAN domain-containing protein 20) (Zinc finger protein 360).

TCF8_HUMAN
NC score	-0.007771 (rank : 153)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	149	Target Neighborhood Hits	1057	Shared Neighborhood Hits	4
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).