Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : E2F3_MOUSE

For an explanation of this page, click here

E2F3_MOUSE
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

E2F3_HUMAN
θ value	0 (rank : 1)	NC score	0.996131 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

E2F3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

E2F2_MOUSE
θ value	1.2666e-86 (rank : 3)	NC score	0.968787 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	P56931, Q8BID0	Gene names	E2f2
Domain Architecture	No domain graphic available
Description	Transcription factor E2F2 (E2F-2).

E2F2_HUMAN
θ value	1.40363e-77 (rank : 4)	NC score	0.961682 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

E2F1_HUMAN
θ value	4.09345e-69 (rank : 5)	NC score	0.960243 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

E2F1_MOUSE
θ value	2.32439e-64 (rank : 6)	NC score	0.957611 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q61501, Q80VZ3	Gene names	E2f1
Domain Architecture
Description	Transcription factor E2F1 (E2F-1).

E2F6_MOUSE
θ value	8.87376e-48 (rank : 7)	NC score	0.939752 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

E2F6_HUMAN
θ value	3.37202e-47 (rank : 8)	NC score	0.941868 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

E2F4_HUMAN
θ value	5.96599e-36 (rank : 9)	NC score	0.862374 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

E2F5_HUMAN
θ value	1.9192e-34 (rank : 10)	NC score	0.879156 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F5_MOUSE
θ value	4.72714e-33 (rank : 11)	NC score	0.877838 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

TDP1_HUMAN
θ value	0.0148317 (rank : 12)	NC score	0.198593 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q14186, Q8IZL5	Gene names	TFDP1, DP1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1) (DRTF1).

TDP1_MOUSE
θ value	0.0148317 (rank : 13)	NC score	0.200964 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q08639	Gene names	Tfdp1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1).

TDP2_HUMAN
θ value	0.0736092 (rank : 14)	NC score	0.158817 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

INADL_MOUSE
θ value	0.163984 (rank : 15)	NC score	0.016776 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

MKL2_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.043491 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	269	Shared Neighborhood Hits	6
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

KNTC2_MOUSE
θ value	0.47712 (rank : 17)	NC score	0.021837 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	692	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

MCR_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.019191 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

TS13_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.058678 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

KIF4A_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.009915 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	1159	Shared Neighborhood Hits	12
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

DESP_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.009383 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	1470	Shared Neighborhood Hits	10
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

MCR_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.017735 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

GOGA1_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.010137 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	1222	Shared Neighborhood Hits	10
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

PRKDC_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.021131 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

CK024_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.018581 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

GPR98_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.012180 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

MKL2_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.032792 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	274	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

SGT1_MOUSE
θ value	2.36792 (rank : 28)	NC score	0.021044 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CS74	Gene names	Ecd, Hsgt1, Sgt1
Domain Architecture
Description	SGT1 protein homolog (Ecdysoneless homolog).

BTBDC_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.020632 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

NRX2A_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.013300 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	614	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

TAF6L_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.015808 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

SHE_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.015693 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

AMOT_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.012486 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	712	Shared Neighborhood Hits	12
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

KAISO_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.001159 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	840	Shared Neighborhood Hits	5
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

MUC5B_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.005152 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	1020	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NRX3A_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.013149 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	164	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

CI093_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.008012 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	1088	Shared Neighborhood Hits	10
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

DLGP2_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.011318 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

GOGA3_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.005282 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	1437	Shared Neighborhood Hits	10
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

KCNT1_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.013996 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

PCSK7_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.009552 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

ZN541_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.010731 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

DOK2_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.006125 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	244	Shared Neighborhood Hits	2
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

FOG1_MOUSE
θ value	8.99809 (rank : 44)	NC score	-0.000188 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	1237	Shared Neighborhood Hits	7
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PERI_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.002537 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	502	Shared Neighborhood Hits	8
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

PYR1_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.006957 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

SHE_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.010446 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	164	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

TDP2_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.062929 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q64163	Gene names	Tfdp2, Dp2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2) (Dp-3).

Hits sorted by NC score

E2F3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

E2F3_HUMAN
NC score	0.996131 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

E2F2_MOUSE
NC score	0.968787 (rank : 3)	θ value	1.2666e-86 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	P56931, Q8BID0	Gene names	E2f2
Domain Architecture	No domain graphic available
Description	Transcription factor E2F2 (E2F-2).

E2F2_HUMAN
NC score	0.961682 (rank : 4)	θ value	1.40363e-77 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

E2F1_HUMAN
NC score	0.960243 (rank : 5)	θ value	4.09345e-69 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

E2F1_MOUSE
NC score	0.957611 (rank : 6)	θ value	2.32439e-64 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q61501, Q80VZ3	Gene names	E2f1
Domain Architecture
Description	Transcription factor E2F1 (E2F-1).

E2F6_HUMAN
NC score	0.941868 (rank : 7)	θ value	3.37202e-47 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

E2F6_MOUSE
NC score	0.939752 (rank : 8)	θ value	8.87376e-48 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

E2F5_HUMAN
NC score	0.879156 (rank : 9)	θ value	1.9192e-34 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F5_MOUSE
NC score	0.877838 (rank : 10)	θ value	4.72714e-33 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F4_HUMAN
NC score	0.862374 (rank : 11)	θ value	5.96599e-36 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

TDP1_MOUSE
NC score	0.200964 (rank : 12)	θ value	0.0148317 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q08639	Gene names	Tfdp1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1).

TDP1_HUMAN
NC score	0.198593 (rank : 13)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q14186, Q8IZL5	Gene names	TFDP1, DP1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1) (DRTF1).

TDP2_HUMAN
NC score	0.158817 (rank : 14)	θ value	0.0736092 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

TDP2_MOUSE
NC score	0.062929 (rank : 15)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q64163	Gene names	Tfdp2, Dp2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2) (Dp-3).

TS13_MOUSE
NC score	0.058678 (rank : 16)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

MKL2_MOUSE
NC score	0.043491 (rank : 17)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	269	Shared Neighborhood Hits	6
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

MKL2_HUMAN
NC score	0.032792 (rank : 18)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	274	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

KNTC2_MOUSE
NC score	0.021837 (rank : 19)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	692	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

PRKDC_HUMAN
NC score	0.021131 (rank : 20)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

SGT1_MOUSE
NC score	0.021044 (rank : 21)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CS74	Gene names	Ecd, Hsgt1, Sgt1
Domain Architecture
Description	SGT1 protein homolog (Ecdysoneless homolog).

BTBDC_HUMAN
NC score	0.020632 (rank : 22)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

MCR_HUMAN
NC score	0.019191 (rank : 23)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

CK024_MOUSE
NC score	0.018581 (rank : 24)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

MCR_MOUSE
NC score	0.017735 (rank : 25)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

INADL_MOUSE
NC score	0.016776 (rank : 26)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

TAF6L_MOUSE
NC score	0.015808 (rank : 27)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

SHE_MOUSE
NC score	0.015693 (rank : 28)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

KCNT1_HUMAN
NC score	0.013996 (rank : 29)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

NRX2A_HUMAN
NC score	0.013300 (rank : 30)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	614	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
NC score	0.013149 (rank : 31)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	164	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

AMOT_HUMAN
NC score	0.012486 (rank : 32)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	712	Shared Neighborhood Hits	12
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

GPR98_HUMAN
NC score	0.012180 (rank : 33)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

DLGP2_MOUSE
NC score	0.011318 (rank : 34)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

ZN541_HUMAN
NC score	0.010731 (rank : 35)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

SHE_HUMAN
NC score	0.010446 (rank : 36)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	164	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

GOGA1_HUMAN
NC score	0.010137 (rank : 37)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	1222	Shared Neighborhood Hits	10
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

KIF4A_HUMAN
NC score	0.009915 (rank : 38)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	1159	Shared Neighborhood Hits	12
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

PCSK7_MOUSE
NC score	0.009552 (rank : 39)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

DESP_HUMAN
NC score	0.009383 (rank : 40)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	1470	Shared Neighborhood Hits	10
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

CI093_HUMAN
NC score	0.008012 (rank : 41)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	1088	Shared Neighborhood Hits	10
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

PYR1_HUMAN
NC score	0.006957 (rank : 42)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

DOK2_MOUSE
NC score	0.006125 (rank : 43)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	244	Shared Neighborhood Hits	2
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

GOGA3_MOUSE
NC score	0.005282 (rank : 44)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	1437	Shared Neighborhood Hits	10
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

MUC5B_HUMAN
NC score	0.005152 (rank : 45)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	1020	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PERI_MOUSE
NC score	0.002537 (rank : 46)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	502	Shared Neighborhood Hits	8
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

KAISO_HUMAN
NC score	0.001159 (rank : 47)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	840	Shared Neighborhood Hits	5
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

FOG1_MOUSE
NC score	-0.000188 (rank : 48)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	1237	Shared Neighborhood Hits	7
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).