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Network neighborhood for query Sequence : E2F2_MOUSE

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E2F2_MOUSE
SwissProt Accessions	P56931, Q8BID0	Gene names	E2f2
Domain Architecture	No domain graphic available
Description	Transcription factor E2F2 (E2F-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

E2F2_HUMAN
θ value	0 (rank : 1)	NC score	0.990559 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

E2F2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	P56931, Q8BID0	Gene names	E2f2
Domain Architecture	No domain graphic available
Description	Transcription factor E2F2 (E2F-2).

E2F3_HUMAN
θ value	1.49618e-87 (rank : 3)	NC score	0.969453 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

E2F3_MOUSE
θ value	1.2666e-86 (rank : 4)	NC score	0.968787 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

E2F1_HUMAN
θ value	2.4834e-66 (rank : 5)	NC score	0.957311 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

E2F1_MOUSE
θ value	4.23606e-66 (rank : 6)	NC score	0.955401 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q61501, Q80VZ3	Gene names	E2f1
Domain Architecture
Description	Transcription factor E2F1 (E2F-1).

E2F6_MOUSE
θ value	1.97686e-47 (rank : 7)	NC score	0.939034 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

E2F6_HUMAN
θ value	7.51208e-47 (rank : 8)	NC score	0.941219 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

E2F4_HUMAN
θ value	2.58786e-39 (rank : 9)	NC score	0.866889 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

E2F5_HUMAN
θ value	1.01765e-35 (rank : 10)	NC score	0.882976 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F5_MOUSE
θ value	1.01765e-35 (rank : 11)	NC score	0.880991 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

RGS3_HUMAN
θ value	0.0736092 (rank : 12)	NC score	0.021471 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	1375	Shared Neighborhood Hits	11
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TDP1_HUMAN
θ value	0.0736092 (rank : 13)	NC score	0.178501 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q14186, Q8IZL5	Gene names	TFDP1, DP1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1) (DRTF1).

TDP1_MOUSE
θ value	0.0736092 (rank : 14)	NC score	0.180819 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q08639	Gene names	Tfdp1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1).

RC3H1_HUMAN
θ value	0.279714 (rank : 15)	NC score	0.022955 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	433	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

MORC4_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.020915 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

K1683_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.042614 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

MAST2_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.003249 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	1189	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TDP2_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.139283 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

KIF5C_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.007529 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	1040	Shared Neighborhood Hits	7
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

PCIF1_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.033967 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

NFX1_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.015129 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	405	Shared Neighborhood Hits	2
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NCOR2_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.011381 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	870	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SDHL_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.019538 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VBT2	Gene names	Sds
Domain Architecture	No domain graphic available
Description	L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase).

IKKE_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.000679 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	848	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

PTN22_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.004948 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

FGD6_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.005216 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

KNG1_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.013142 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P01042, P01043	Gene names	KNG1, BDK, KNG
Domain Architecture
Description	Kininogen-1 precursor (Alpha-2-thiol proteinase inhibitor) [Contains: Kininogen-1 heavy chain; Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth- promoting factor].

SHAN2_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.013912 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	446	Shared Neighborhood Hits	6
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SP2_HUMAN
θ value	5.27518 (rank : 30)	NC score	-0.000866 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	747	Shared Neighborhood Hits	2
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

LBXCO_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.015942 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

MDC1_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.019839 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	1446	Shared Neighborhood Hits	12
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYPN_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.003123 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	421	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

SHAN2_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.014589 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	346	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

TACC1_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.008766 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	597	Shared Neighborhood Hits	5
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.008650 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	667	Shared Neighborhood Hits	7
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TF2AA_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.011768 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P52655	Gene names	GTF2A1, TF2A1
Domain Architecture
Description	Transcription initiation factor IIA subunit 1 (General transcription factor IIA1) (TFIIA-42) (TFIIAL) [Contains: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)].

CN145_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.005075 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	916	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CS029_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.009195 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	329	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

HIPK2_HUMAN
θ value	8.99809 (rank : 40)	NC score	-0.000105 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	845	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

PRG4_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.007000 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	764	Shared Neighborhood Hits	9
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TFEB_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.006650 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

Hits sorted by NC score

E2F2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	P56931, Q8BID0	Gene names	E2f2
Domain Architecture	No domain graphic available
Description	Transcription factor E2F2 (E2F-2).

E2F2_HUMAN
NC score	0.990559 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

E2F3_HUMAN
NC score	0.969453 (rank : 3)	θ value	1.49618e-87 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

E2F3_MOUSE
NC score	0.968787 (rank : 4)	θ value	1.2666e-86 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

E2F1_HUMAN
NC score	0.957311 (rank : 5)	θ value	2.4834e-66 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

E2F1_MOUSE
NC score	0.955401 (rank : 6)	θ value	4.23606e-66 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q61501, Q80VZ3	Gene names	E2f1
Domain Architecture
Description	Transcription factor E2F1 (E2F-1).

E2F6_HUMAN
NC score	0.941219 (rank : 7)	θ value	7.51208e-47 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

E2F6_MOUSE
NC score	0.939034 (rank : 8)	θ value	1.97686e-47 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

E2F5_HUMAN
NC score	0.882976 (rank : 9)	θ value	1.01765e-35 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F5_MOUSE
NC score	0.880991 (rank : 10)	θ value	1.01765e-35 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F4_HUMAN
NC score	0.866889 (rank : 11)	θ value	2.58786e-39 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

TDP1_MOUSE
NC score	0.180819 (rank : 12)	θ value	0.0736092 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q08639	Gene names	Tfdp1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1).

TDP1_HUMAN
NC score	0.178501 (rank : 13)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q14186, Q8IZL5	Gene names	TFDP1, DP1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1) (DRTF1).

TDP2_HUMAN
NC score	0.139283 (rank : 14)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

K1683_HUMAN
NC score	0.042614 (rank : 15)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

PCIF1_HUMAN
NC score	0.033967 (rank : 16)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

RC3H1_HUMAN
NC score	0.022955 (rank : 17)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	433	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RGS3_HUMAN
NC score	0.021471 (rank : 18)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	1375	Shared Neighborhood Hits	11
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MORC4_MOUSE
NC score	0.020915 (rank : 19)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

MDC1_HUMAN
NC score	0.019839 (rank : 20)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	1446	Shared Neighborhood Hits	12
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SDHL_MOUSE
NC score	0.019538 (rank : 21)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VBT2	Gene names	Sds
Domain Architecture	No domain graphic available
Description	L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase).

LBXCO_MOUSE
NC score	0.015942 (rank : 22)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

NFX1_HUMAN
NC score	0.015129 (rank : 23)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	405	Shared Neighborhood Hits	2
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

SHAN2_HUMAN
NC score	0.014589 (rank : 24)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	346	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
NC score	0.013912 (rank : 25)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	446	Shared Neighborhood Hits	6
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

KNG1_HUMAN
NC score	0.013142 (rank : 26)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P01042, P01043	Gene names	KNG1, BDK, KNG
Domain Architecture
Description	Kininogen-1 precursor (Alpha-2-thiol proteinase inhibitor) [Contains: Kininogen-1 heavy chain; Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth- promoting factor].

TF2AA_HUMAN
NC score	0.011768 (rank : 27)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P52655	Gene names	GTF2A1, TF2A1
Domain Architecture
Description	Transcription initiation factor IIA subunit 1 (General transcription factor IIA1) (TFIIA-42) (TFIIAL) [Contains: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)].

NCOR2_HUMAN
NC score	0.011381 (rank : 28)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	870	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CS029_HUMAN
NC score	0.009195 (rank : 29)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	329	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

TACC1_HUMAN
NC score	0.008766 (rank : 30)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	597	Shared Neighborhood Hits	5
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
NC score	0.008650 (rank : 31)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	667	Shared Neighborhood Hits	7
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

KIF5C_MOUSE
NC score	0.007529 (rank : 32)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	1040	Shared Neighborhood Hits	7
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

PRG4_HUMAN
NC score	0.007000 (rank : 33)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	764	Shared Neighborhood Hits	9
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TFEB_MOUSE
NC score	0.006650 (rank : 34)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

FGD6_HUMAN
NC score	0.005216 (rank : 35)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

CN145_MOUSE
NC score	0.005075 (rank : 36)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	916	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

PTN22_MOUSE
NC score	0.004948 (rank : 37)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

MAST2_HUMAN
NC score	0.003249 (rank : 38)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	1189	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MYPN_MOUSE
NC score	0.003123 (rank : 39)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	421	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

IKKE_MOUSE
NC score	0.000679 (rank : 40)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	848	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

HIPK2_HUMAN
NC score	-0.000105 (rank : 41)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	845	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

SP2_HUMAN
NC score	-0.000866 (rank : 42)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	747	Shared Neighborhood Hits	2
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.