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Network neighborhood for query Sequence : E2F4_HUMAN

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E2F4_HUMAN
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

E2F4_HUMAN
θ value	1.71888e-184 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	188	Target Neighborhood Hits	188	Shared Neighborhood Hits	188
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

E2F5_HUMAN
θ value	6.73165e-80 (rank : 2)	NC score	0.942360 (rank : 2)
Query Neighborhood Hits	188	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F5_MOUSE
θ value	4.08394e-77 (rank : 3)	NC score	0.942132 (rank : 3)
Query Neighborhood Hits	188	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F2_MOUSE
θ value	2.58786e-39 (rank : 4)	NC score	0.866889 (rank : 4)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P56931, Q8BID0	Gene names	E2f2
Domain Architecture	No domain graphic available
Description	Transcription factor E2F2 (E2F-2).

E2F3_MOUSE
θ value	5.96599e-36 (rank : 5)	NC score	0.862374 (rank : 6)
Query Neighborhood Hits	188	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

E2F3_HUMAN
θ value	1.01765e-35 (rank : 6)	NC score	0.862133 (rank : 8)
Query Neighborhood Hits	188	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

E2F2_HUMAN
θ value	2.77131e-33 (rank : 7)	NC score	0.862009 (rank : 9)
Query Neighborhood Hits	188	Target Neighborhood Hits	76	Shared Neighborhood Hits	19
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

E2F1_HUMAN
θ value	1.08979e-29 (rank : 8)	NC score	0.846948 (rank : 10)
Query Neighborhood Hits	188	Target Neighborhood Hits	41	Shared Neighborhood Hits	16
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

E2F6_MOUSE
θ value	3.17079e-29 (rank : 9)	NC score	0.862174 (rank : 7)
Query Neighborhood Hits	188	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

E2F6_HUMAN
θ value	1.02001e-27 (rank : 10)	NC score	0.862689 (rank : 5)
Query Neighborhood Hits	188	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

E2F1_MOUSE
θ value	2.20094e-22 (rank : 11)	NC score	0.837497 (rank : 11)
Query Neighborhood Hits	188	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	Q61501, Q80VZ3	Gene names	E2f1
Domain Architecture
Description	Transcription factor E2F1 (E2F-1).

MAGE1_HUMAN
θ value	0.00134147 (rank : 12)	NC score	0.077546 (rank : 18)
Query Neighborhood Hits	188	Target Neighborhood Hits	1389	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MDC1_HUMAN
θ value	0.0148317 (rank : 13)	NC score	0.086564 (rank : 15)
Query Neighborhood Hits	188	Target Neighborhood Hits	1446	Shared Neighborhood Hits	91
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

DOT1L_HUMAN
θ value	0.0252991 (rank : 14)	NC score	0.084343 (rank : 16)
Query Neighborhood Hits	188	Target Neighborhood Hits	660	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GCNL2_HUMAN
θ value	0.0252991 (rank : 15)	NC score	0.041645 (rank : 74)
Query Neighborhood Hits	188	Target Neighborhood Hits	159	Shared Neighborhood Hits	12
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

MYH6_MOUSE
θ value	0.0252991 (rank : 16)	NC score	0.066247 (rank : 25)
Query Neighborhood Hits	188	Target Neighborhood Hits	1501	Shared Neighborhood Hits	35
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	0.0252991 (rank : 17)	NC score	0.066349 (rank : 24)
Query Neighborhood Hits	188	Target Neighborhood Hits	1559	Shared Neighborhood Hits	36
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

KCNB2_HUMAN
θ value	0.0431538 (rank : 18)	NC score	0.021779 (rank : 142)
Query Neighborhood Hits	188	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

MYH8_HUMAN
θ value	0.0431538 (rank : 19)	NC score	0.066756 (rank : 22)
Query Neighborhood Hits	188	Target Neighborhood Hits	1610	Shared Neighborhood Hits	45
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	0.0431538 (rank : 20)	NC score	0.066462 (rank : 23)
Query Neighborhood Hits	188	Target Neighborhood Hits	1600	Shared Neighborhood Hits	40
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PGCA_MOUSE
θ value	0.0961366 (rank : 21)	NC score	0.038107 (rank : 85)
Query Neighborhood Hits	188	Target Neighborhood Hits	643	Shared Neighborhood Hits	37
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

ZN638_HUMAN
θ value	0.0961366 (rank : 22)	NC score	0.056614 (rank : 47)
Query Neighborhood Hits	188	Target Neighborhood Hits	343	Shared Neighborhood Hits	24
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

MYH6_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.065161 (rank : 28)
Query Neighborhood Hits	188	Target Neighborhood Hits	1426	Shared Neighborhood Hits	35
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

HUWE1_MOUSE
θ value	0.163984 (rank : 24)	NC score	0.036816 (rank : 91)
Query Neighborhood Hits	188	Target Neighborhood Hits	406	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

IRS2_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.056533 (rank : 48)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

KGP2_HUMAN
θ value	0.163984 (rank : 26)	NC score	0.008228 (rank : 174)
Query Neighborhood Hits	188	Target Neighborhood Hits	1023	Shared Neighborhood Hits	27
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

MNT_HUMAN
θ value	0.163984 (rank : 27)	NC score	0.058497 (rank : 39)
Query Neighborhood Hits	188	Target Neighborhood Hits	496	Shared Neighborhood Hits	47
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

URFB1_HUMAN
θ value	0.163984 (rank : 28)	NC score	0.057297 (rank : 44)
Query Neighborhood Hits	188	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

MYH4_MOUSE
θ value	0.21417 (rank : 29)	NC score	0.065872 (rank : 26)
Query Neighborhood Hits	188	Target Neighborhood Hits	1476	Shared Neighborhood Hits	41
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

SAPS1_HUMAN
θ value	0.21417 (rank : 30)	NC score	0.052945 (rank : 54)
Query Neighborhood Hits	188	Target Neighborhood Hits	704	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ARMX2_MOUSE
θ value	0.365318 (rank : 31)	NC score	0.048704 (rank : 60)
Query Neighborhood Hits	188	Target Neighborhood Hits	349	Shared Neighborhood Hits	53
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

MLL3_HUMAN
θ value	0.365318 (rank : 32)	NC score	0.058525 (rank : 38)
Query Neighborhood Hits	188	Target Neighborhood Hits	1644	Shared Neighborhood Hits	95
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MUC2_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.045655 (rank : 66)
Query Neighborhood Hits	188	Target Neighborhood Hits	906	Shared Neighborhood Hits	54
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PI5PA_HUMAN
θ value	0.365318 (rank : 34)	NC score	0.077891 (rank : 17)
Query Neighborhood Hits	188	Target Neighborhood Hits	749	Shared Neighborhood Hits	86
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ZFYV9_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.026716 (rank : 123)
Query Neighborhood Hits	188	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

GBX1_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.007956 (rank : 177)
Query Neighborhood Hits	188	Target Neighborhood Hits	334	Shared Neighborhood Hits	4
SwissProt Accessions	Q14549	Gene names	GBX1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

HUWE1_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.035437 (rank : 95)
Query Neighborhood Hits	188	Target Neighborhood Hits	443	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

NU214_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.067410 (rank : 21)
Query Neighborhood Hits	188	Target Neighborhood Hits	657	Shared Neighborhood Hits	50
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PPRB_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.051742 (rank : 56)
Query Neighborhood Hits	188	Target Neighborhood Hits	354	Shared Neighborhood Hits	31
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SHB_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.022850 (rank : 134)
Query Neighborhood Hits	188	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SYNJ1_MOUSE
θ value	0.47712 (rank : 41)	NC score	0.061617 (rank : 34)
Query Neighborhood Hits	188	Target Neighborhood Hits	516	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CBP_MOUSE
θ value	0.62314 (rank : 42)	NC score	0.054594 (rank : 52)
Query Neighborhood Hits	188	Target Neighborhood Hits	1051	Shared Neighborhood Hits	77
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CENG1_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.017213 (rank : 149)
Query Neighborhood Hits	188	Target Neighborhood Hits	531	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CO3A1_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.038635 (rank : 83)
Query Neighborhood Hits	188	Target Neighborhood Hits	452	Shared Neighborhood Hits	32
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	0.62314 (rank : 45)	NC score	0.037023 (rank : 89)
Query Neighborhood Hits	188	Target Neighborhood Hits	466	Shared Neighborhood Hits	32
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

HCN2_MOUSE
θ value	0.62314 (rank : 46)	NC score	0.027586 (rank : 121)
Query Neighborhood Hits	188	Target Neighborhood Hits	278	Shared Neighborhood Hits	28
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HSF1_MOUSE
θ value	0.62314 (rank : 47)	NC score	0.036239 (rank : 92)
Query Neighborhood Hits	188	Target Neighborhood Hits	267	Shared Neighborhood Hits	29
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

MUC7_HUMAN
θ value	0.62314 (rank : 48)	NC score	0.073458 (rank : 19)
Query Neighborhood Hits	188	Target Neighborhood Hits	538	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MYH1_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.065719 (rank : 27)
Query Neighborhood Hits	188	Target Neighborhood Hits	1478	Shared Neighborhood Hits	40
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

BAT2_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.055365 (rank : 51)
Query Neighborhood Hits	188	Target Neighborhood Hits	931	Shared Neighborhood Hits	73
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FMNL_MOUSE
θ value	0.813845 (rank : 51)	NC score	0.043573 (rank : 71)
Query Neighborhood Hits	188	Target Neighborhood Hits	428	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FSBP_MOUSE
θ value	0.813845 (rank : 52)	NC score	0.036077 (rank : 93)
Query Neighborhood Hits	188	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BKE5, Q8BJX8	Gene names	Fsbp
Domain Architecture	No domain graphic available
Description	Fibrinogen silencer-binding protein.

KCNC3_MOUSE
θ value	0.813845 (rank : 53)	NC score	0.016646 (rank : 150)
Query Neighborhood Hits	188	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

MLL2_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.046177 (rank : 65)
Query Neighborhood Hits	188	Target Neighborhood Hits	1788	Shared Neighborhood Hits	86
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYH1_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.065035 (rank : 29)
Query Neighborhood Hits	188	Target Neighborhood Hits	1461	Shared Neighborhood Hits	40
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

RAPH1_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.051560 (rank : 57)
Query Neighborhood Hits	188	Target Neighborhood Hits	593	Shared Neighborhood Hits	50
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SALL3_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.010318 (rank : 168)
Query Neighborhood Hits	188	Target Neighborhood Hits	1066	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SYNJ1_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.060533 (rank : 36)
Query Neighborhood Hits	188	Target Neighborhood Hits	498	Shared Neighborhood Hits	49
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

WNK4_HUMAN
θ value	0.813845 (rank : 59)	NC score	0.014500 (rank : 157)
Query Neighborhood Hits	188	Target Neighborhood Hits	1043	Shared Neighborhood Hits	37
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZC3H6_MOUSE
θ value	0.813845 (rank : 60)	NC score	0.031524 (rank : 105)
Query Neighborhood Hits	188	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

AKTS1_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.038759 (rank : 81)
Query Neighborhood Hits	188	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1F4	Gene names	Akt1s1, Pras
Domain Architecture	No domain graphic available
Description	Proline-rich AKT1 substrate 1 (Proline-rich AKT substrate).

AP180_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.044406 (rank : 67)
Query Neighborhood Hits	188	Target Neighborhood Hits	183	Shared Neighborhood Hits	24
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

I12R2_HUMAN
θ value	1.06291 (rank : 63)	NC score	0.018627 (rank : 146)
Query Neighborhood Hits	188	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

IRS2_MOUSE
θ value	1.06291 (rank : 64)	NC score	0.051162 (rank : 59)
Query Neighborhood Hits	188	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MYH2_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.062823 (rank : 32)
Query Neighborhood Hits	188	Target Neighborhood Hits	1491	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

PCX3_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.033884 (rank : 99)
Query Neighborhood Hits	188	Target Neighborhood Hits	134	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

PI5PA_MOUSE
θ value	1.06291 (rank : 67)	NC score	0.058379 (rank : 40)
Query Neighborhood Hits	188	Target Neighborhood Hits	331	Shared Neighborhood Hits	33
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RCOR2_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.028009 (rank : 120)
Query Neighborhood Hits	188	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

SOX13_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.027090 (rank : 122)
Query Neighborhood Hits	188	Target Neighborhood Hits	464	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SYNPO_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.047238 (rank : 64)
Query Neighborhood Hits	188	Target Neighborhood Hits	281	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TAF10_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.040012 (rank : 79)
Query Neighborhood Hits	188	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q12962, O00703, Q13175	Gene names	TAF10, TAF2H, TAFII30
Domain Architecture
Description	Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) (STAF28).

WNK1_MOUSE
θ value	1.06291 (rank : 72)	NC score	0.015826 (rank : 154)
Query Neighborhood Hits	188	Target Neighborhood Hits	1179	Shared Neighborhood Hits	49
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ZN142_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.002532 (rank : 190)
Query Neighborhood Hits	188	Target Neighborhood Hits	1007	Shared Neighborhood Hits	41
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

CO039_MOUSE
θ value	1.38821 (rank : 74)	NC score	0.052930 (rank : 55)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	55
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

K2002_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.021901 (rank : 141)
Query Neighborhood Hits	188	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H792, Q6ZS78, Q8NCM3	Gene names	KIAA2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

MYH13_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.061634 (rank : 33)
Query Neighborhood Hits	188	Target Neighborhood Hits	1504	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

PCLO_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.043943 (rank : 68)
Query Neighborhood Hits	188	Target Neighborhood Hits	2046	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PGCA_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.039681 (rank : 80)
Query Neighborhood Hits	188	Target Neighborhood Hits	821	Shared Neighborhood Hits	54
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PHC1_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.033433 (rank : 101)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

TISD_MOUSE
θ value	1.38821 (rank : 80)	NC score	0.025641 (rank : 126)
Query Neighborhood Hits	188	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

YTHD1_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.022511 (rank : 137)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

CO1A2_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.031899 (rank : 104)
Query Neighborhood Hits	188	Target Neighborhood Hits	329	Shared Neighborhood Hits	20
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO9A3_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.021570 (rank : 143)
Query Neighborhood Hits	188	Target Neighborhood Hits	361	Shared Neighborhood Hits	20
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

EP400_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.025677 (rank : 125)
Query Neighborhood Hits	188	Target Neighborhood Hits	556	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

HCN2_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.028947 (rank : 112)
Query Neighborhood Hits	188	Target Neighborhood Hits	369	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

IL2RB_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.025568 (rank : 127)
Query Neighborhood Hits	188	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

MAGD4_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.035672 (rank : 94)
Query Neighborhood Hits	188	Target Neighborhood Hits	338	Shared Neighborhood Hits	50
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

SPEG_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.011131 (rank : 167)
Query Neighborhood Hits	188	Target Neighborhood Hits	1959	Shared Neighborhood Hits	75
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

WBS14_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.037142 (rank : 88)
Query Neighborhood Hits	188	Target Neighborhood Hits	273	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WNK1_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.015769 (rank : 155)
Query Neighborhood Hits	188	Target Neighborhood Hits	1158	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ZEP1_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.013039 (rank : 160)
Query Neighborhood Hits	188	Target Neighborhood Hits	1063	Shared Neighborhood Hits	48
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

3BP1_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.025701 (rank : 124)
Query Neighborhood Hits	188	Target Neighborhood Hits	376	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AMOT_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.043914 (rank : 69)
Query Neighborhood Hits	188	Target Neighborhood Hits	712	Shared Neighborhood Hits	47
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

IRAK1_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.005691 (rank : 182)
Query Neighborhood Hits	188	Target Neighborhood Hits	784	Shared Neighborhood Hits	15
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

KGP2_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.006389 (rank : 181)
Query Neighborhood Hits	188	Target Neighborhood Hits	1029	Shared Neighborhood Hits	26
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

MYH3_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.057825 (rank : 42)
Query Neighborhood Hits	188	Target Neighborhood Hits	1660	Shared Neighborhood Hits	37
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PCNT_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.028396 (rank : 116)
Query Neighborhood Hits	188	Target Neighborhood Hits	1551	Shared Neighborhood Hits	41
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PELP1_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.048413 (rank : 62)
Query Neighborhood Hits	188	Target Neighborhood Hits	709	Shared Neighborhood Hits	61
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PLXB1_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.018215 (rank : 148)
Query Neighborhood Hits	188	Target Neighborhood Hits	360	Shared Neighborhood Hits	38
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

SRRM2_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.051194 (rank : 58)
Query Neighborhood Hits	188	Target Neighborhood Hits	1296	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TAF4_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.055646 (rank : 50)
Query Neighborhood Hits	188	Target Neighborhood Hits	687	Shared Neighborhood Hits	52
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TR10C_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.021025 (rank : 144)
Query Neighborhood Hits	188	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

ADA12_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.004766 (rank : 183)
Query Neighborhood Hits	188	Target Neighborhood Hits	224	Shared Neighborhood Hits	8
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CE152_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.035198 (rank : 97)
Query Neighborhood Hits	188	Target Neighborhood Hits	976	Shared Neighborhood Hits	28
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

COBA2_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.022613 (rank : 135)
Query Neighborhood Hits	188	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CR025_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.024929 (rank : 129)
Query Neighborhood Hits	188	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q96B23, Q5XG78, Q6N058, Q86TB5, Q8TCQ5	Gene names	C18orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25.

CYLN2_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.034271 (rank : 98)
Query Neighborhood Hits	188	Target Neighborhood Hits	1002	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

NCOA6_MOUSE
θ value	3.0926 (rank : 108)	NC score	0.058133 (rank : 41)
Query Neighborhood Hits	188	Target Neighborhood Hits	1076	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOR2_MOUSE
θ value	3.0926 (rank : 109)	NC score	0.029663 (rank : 110)
Query Neighborhood Hits	188	Target Neighborhood Hits	790	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NF2L1_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.028193 (rank : 119)
Query Neighborhood Hits	188	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L1_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.028280 (rank : 117)
Query Neighborhood Hits	188	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

ODO2_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.020264 (rank : 145)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

RBM12_MOUSE
θ value	3.0926 (rank : 113)	NC score	0.028262 (rank : 118)
Query Neighborhood Hits	188	Target Neighborhood Hits	313	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SYNP2_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.033630 (rank : 100)
Query Neighborhood Hits	188	Target Neighborhood Hits	252	Shared Neighborhood Hits	20
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

TARA_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.047347 (rank : 63)
Query Neighborhood Hits	188	Target Neighborhood Hits	1626	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GA2L3_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.025092 (rank : 128)
Query Neighborhood Hits	188	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

MAVS_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.048454 (rank : 61)
Query Neighborhood Hits	188	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MLL4_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.040819 (rank : 76)
Query Neighborhood Hits	188	Target Neighborhood Hits	722	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SMR1_MOUSE
θ value	4.03905 (rank : 119)	NC score	0.040114 (rank : 78)
Query Neighborhood Hits	188	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

ST2B1_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.008139 (rank : 175)
Query Neighborhood Hits	188	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

SYNP2_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.030468 (rank : 108)
Query Neighborhood Hits	188	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TAF6_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.030990 (rank : 107)
Query Neighborhood Hits	188	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

TGON2_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.032179 (rank : 103)
Query Neighborhood Hits	188	Target Neighborhood Hits	1037	Shared Neighborhood Hits	50
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIE1_HUMAN
θ value	4.03905 (rank : 124)	NC score	-0.000265 (rank : 193)
Query Neighborhood Hits	188	Target Neighborhood Hits	1241	Shared Neighborhood Hits	19
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

AIRE_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.016481 (rank : 151)
Query Neighborhood Hits	188	Target Neighborhood Hits	144	Shared Neighborhood Hits	11
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

ATX1_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.030190 (rank : 109)
Query Neighborhood Hits	188	Target Neighborhood Hits	264	Shared Neighborhood Hits	27
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

CK5P2_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.029139 (rank : 111)
Query Neighborhood Hits	188	Target Neighborhood Hits	1151	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CNOT3_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.043664 (rank : 70)
Query Neighborhood Hits	188	Target Neighborhood Hits	425	Shared Neighborhood Hits	37
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

COBA2_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.022301 (rank : 139)
Query Neighborhood Hits	188	Target Neighborhood Hits	501	Shared Neighborhood Hits	33
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CS007_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.036872 (rank : 90)
Query Neighborhood Hits	188	Target Neighborhood Hits	401	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CYLN2_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.032711 (rank : 102)
Query Neighborhood Hits	188	Target Neighborhood Hits	1004	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

FHOD1_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.022604 (rank : 136)
Query Neighborhood Hits	188	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

K1802_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.038488 (rank : 84)
Query Neighborhood Hits	188	Target Neighborhood Hits	1596	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LTB1L_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.008749 (rank : 171)
Query Neighborhood Hits	188	Target Neighborhood Hits	514	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.008565 (rank : 172)
Query Neighborhood Hits	188	Target Neighborhood Hits	479	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MUC15_MOUSE
θ value	5.27518 (rank : 136)	NC score	0.022472 (rank : 138)
Query Neighborhood Hits	188	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C6Z1, Q3UQC4, Q6XYQ9, Q7TMH6, Q8CE82	Gene names	Muc15
Domain Architecture	No domain graphic available
Description	Mucin-15 precursor.

PGLB_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.003730 (rank : 187)
Query Neighborhood Hits	188	Target Neighborhood Hits	250	Shared Neighborhood Hits	2
SwissProt Accessions	Q99645, Q8NEJ5	Gene names	DSPG3, PGLB
Domain Architecture
Description	Dermatan sulfate proteoglycan 3 precursor (Epiphycan) (Small chondroitin/dermatan sulfate proteoglycan) (Proteoglycan-Lb) (PG-Lb).

RCOR2_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.023786 (rank : 131)
Query Neighborhood Hits	188	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

SCRT1_MOUSE
θ value	5.27518 (rank : 139)	NC score	-0.000749 (rank : 196)
Query Neighborhood Hits	188	Target Neighborhood Hits	703	Shared Neighborhood Hits	11
SwissProt Accessions	Q99M85	Gene names	Scrt1
Domain Architecture	No domain graphic available
Description	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (Scratch 1) (SCRT) (mScrt).

SNPC4_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.041421 (rank : 75)
Query Neighborhood Hits	188	Target Neighborhood Hits	589	Shared Neighborhood Hits	62
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

TNKS1_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.006941 (rank : 180)
Query Neighborhood Hits	188	Target Neighborhood Hits	477	Shared Neighborhood Hits	17
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

UBE4B_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.022283 (rank : 140)
Query Neighborhood Hits	188	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

ZMYM3_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.016315 (rank : 152)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

CN155_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.038701 (rank : 82)
Query Neighborhood Hits	188	Target Neighborhood Hits	385	Shared Neighborhood Hits	35
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CO1A1_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.031361 (rank : 106)
Query Neighborhood Hits	188	Target Neighborhood Hits	475	Shared Neighborhood Hits	34
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO2A1_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.028861 (rank : 113)
Query Neighborhood Hits	188	Target Neighborhood Hits	483	Shared Neighborhood Hits	30
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

DBP_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.011333 (rank : 165)
Query Neighborhood Hits	188	Target Neighborhood Hits	137	Shared Neighborhood Hits	6
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

EGR4_MOUSE
θ value	6.88961 (rank : 148)	NC score	-0.000146 (rank : 192)
Query Neighborhood Hits	188	Target Neighborhood Hits	710	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WUF2	Gene names	Egr4
Domain Architecture
Description	Early growth response protein 4 (EGR-4).

FMNL_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.043432 (rank : 72)
Query Neighborhood Hits	188	Target Neighborhood Hits	529	Shared Neighborhood Hits	46
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FOXF2_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.004050 (rank : 185)
Query Neighborhood Hits	188	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

HRSL5_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.011435 (rank : 164)
Query Neighborhood Hits	188	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

KLF3_MOUSE
θ value	6.88961 (rank : 152)	NC score	-0.000505 (rank : 195)
Query Neighborhood Hits	188	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	Q60980	Gene names	Klf3, Bklf
Domain Architecture
Description	Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2).

LAMB3_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.012325 (rank : 161)
Query Neighborhood Hits	188	Target Neighborhood Hits	444	Shared Neighborhood Hits	22
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

MINT_MOUSE
θ value	6.88961 (rank : 154)	NC score	0.037196 (rank : 87)
Query Neighborhood Hits	188	Target Neighborhood Hits	1514	Shared Neighborhood Hits	88
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MK07_MOUSE
θ value	6.88961 (rank : 155)	NC score	0.004396 (rank : 184)
Query Neighborhood Hits	188	Target Neighborhood Hits	1054	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MTR1L_HUMAN
θ value	6.88961 (rank : 156)	NC score	0.001061 (rank : 191)
Query Neighborhood Hits	188	Target Neighborhood Hits	1180	Shared Neighborhood Hits	30
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NACAM_MOUSE
θ value	6.88961 (rank : 157)	NC score	0.071170 (rank : 20)
Query Neighborhood Hits	188	Target Neighborhood Hits	1866	Shared Neighborhood Hits	111
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.057486 (rank : 43)
Query Neighborhood Hits	188	Target Neighborhood Hits	1202	Shared Neighborhood Hits	91
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PHAR3_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.013990 (rank : 158)
Query Neighborhood Hits	188	Target Neighborhood Hits	169	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PTPRJ_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.002580 (rank : 189)
Query Neighborhood Hits	188	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

SBK1_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.002865 (rank : 188)
Query Neighborhood Hits	188	Target Neighborhood Hits	824	Shared Neighborhood Hits	14
SwissProt Accessions	Q8QZX0	Gene names	Sbk1, Sbk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

SETD2_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.023614 (rank : 132)
Query Neighborhood Hits	188	Target Neighborhood Hits	412	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SFPQ_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.023576 (rank : 133)
Query Neighborhood Hits	188	Target Neighborhood Hits	958	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SHAN1_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.016271 (rank : 153)
Query Neighborhood Hits	188	Target Neighborhood Hits	1041	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SOX3_HUMAN
θ value	6.88961 (rank : 165)	NC score	0.007135 (rank : 179)
Query Neighborhood Hits	188	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

TACC3_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.042547 (rank : 73)
Query Neighborhood Hits	188	Target Neighborhood Hits	779	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TDP1_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.136925 (rank : 13)
Query Neighborhood Hits	188	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q14186, Q8IZL5	Gene names	TFDP1, DP1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1) (DRTF1).

TDP1_MOUSE
θ value	6.88961 (rank : 168)	NC score	0.139445 (rank : 12)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q08639	Gene names	Tfdp1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1).

TDP2_HUMAN
θ value	6.88961 (rank : 169)	NC score	0.108149 (rank : 14)
Query Neighborhood Hits	188	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

ARMX2_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.028511 (rank : 115)
Query Neighborhood Hits	188	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

CENPU_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.018437 (rank : 147)
Query Neighborhood Hits	188	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CO039_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.040381 (rank : 77)
Query Neighborhood Hits	188	Target Neighborhood Hits	264	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CRTC1_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.028616 (rank : 114)
Query Neighborhood Hits	188	Target Neighborhood Hits	319	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CS007_MOUSE
θ value	8.99809 (rank : 174)	NC score	0.037974 (rank : 86)
Query Neighborhood Hits	188	Target Neighborhood Hits	464	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

FBXL5_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.008956 (rank : 170)
Query Neighborhood Hits	188	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FOG1_MOUSE
θ value	8.99809 (rank : 176)	NC score	0.012264 (rank : 162)
Query Neighborhood Hits	188	Target Neighborhood Hits	1237	Shared Neighborhood Hits	65
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOXGB_HUMAN
θ value	8.99809 (rank : 177)	NC score	0.003921 (rank : 186)
Query Neighborhood Hits	188	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

GNDS_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.013101 (rank : 159)
Query Neighborhood Hits	188	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

LSP1_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.015274 (rank : 156)
Query Neighborhood Hits	188	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

LTB1L_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.008518 (rank : 173)
Query Neighborhood Hits	188	Target Neighborhood Hits	553	Shared Neighborhood Hits	23
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.007996 (rank : 176)
Query Neighborhood Hits	188	Target Neighborhood Hits	502	Shared Neighborhood Hits	18
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MTF1_HUMAN
θ value	8.99809 (rank : 182)	NC score	-0.000309 (rank : 194)
Query Neighborhood Hits	188	Target Neighborhood Hits	814	Shared Neighborhood Hits	23
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

PI4KB_MOUSE
θ value	8.99809 (rank : 183)	NC score	0.007955 (rank : 178)
Query Neighborhood Hits	188	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

PO121_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.035406 (rank : 96)
Query Neighborhood Hits	188	Target Neighborhood Hits	344	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PRDM2_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.010281 (rank : 169)
Query Neighborhood Hits	188	Target Neighborhood Hits	1135	Shared Neighborhood Hits	42
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

STAR8_HUMAN
θ value	8.99809 (rank : 186)	NC score	0.011149 (rank : 166)
Query Neighborhood Hits	188	Target Neighborhood Hits	216	Shared Neighborhood Hits	24
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

UBXD2_MOUSE
θ value	8.99809 (rank : 187)	NC score	0.011930 (rank : 163)
Query Neighborhood Hits	188	Target Neighborhood Hits	183	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

WWP1_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.024636 (rank : 130)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

CK024_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.057115 (rank : 45)
Query Neighborhood Hits	188	Target Neighborhood Hits	408	Shared Neighborhood Hits	55
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

MDC1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.061528 (rank : 35)
Query Neighborhood Hits	188	Target Neighborhood Hits	998	Shared Neighborhood Hits	77
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MUC1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.064391 (rank : 30)
Query Neighborhood Hits	188	Target Neighborhood Hits	975	Shared Neighborhood Hits	86
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MYH4_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.063864 (rank : 31)
Query Neighborhood Hits	188	Target Neighborhood Hits	1377	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYO15_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.056666 (rank : 46)
Query Neighborhood Hits	188	Target Neighborhood Hits	671	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO15_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.053808 (rank : 53)
Query Neighborhood Hits	188	Target Neighborhood Hits	467	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

OGFR_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.056000 (rank : 49)
Query Neighborhood Hits	188	Target Neighborhood Hits	1582	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SON_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.059298 (rank : 37)
Query Neighborhood Hits	188	Target Neighborhood Hits	1568	Shared Neighborhood Hits	103
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

Hits sorted by NC score

E2F4_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.71888e-184 (rank : 1)
Query Neighborhood Hits	188	Target Neighborhood Hits	188	Shared Neighborhood Hits	188
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

E2F5_HUMAN
NC score	0.942360 (rank : 2)	θ value	6.73165e-80 (rank : 2)
Query Neighborhood Hits	188	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F5_MOUSE
NC score	0.942132 (rank : 3)	θ value	4.08394e-77 (rank : 3)
Query Neighborhood Hits	188	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F2_MOUSE
NC score	0.866889 (rank : 4)	θ value	2.58786e-39 (rank : 4)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P56931, Q8BID0	Gene names	E2f2
Domain Architecture	No domain graphic available
Description	Transcription factor E2F2 (E2F-2).

E2F6_HUMAN
NC score	0.862689 (rank : 5)	θ value	1.02001e-27 (rank : 10)
Query Neighborhood Hits	188	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

E2F3_MOUSE
NC score	0.862374 (rank : 6)	θ value	5.96599e-36 (rank : 5)
Query Neighborhood Hits	188	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

E2F6_MOUSE
NC score	0.862174 (rank : 7)	θ value	3.17079e-29 (rank : 9)
Query Neighborhood Hits	188	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

E2F3_HUMAN
NC score	0.862133 (rank : 8)	θ value	1.01765e-35 (rank : 6)
Query Neighborhood Hits	188	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

E2F2_HUMAN
NC score	0.862009 (rank : 9)	θ value	2.77131e-33 (rank : 7)
Query Neighborhood Hits	188	Target Neighborhood Hits	76	Shared Neighborhood Hits	19
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

E2F1_HUMAN
NC score	0.846948 (rank : 10)	θ value	1.08979e-29 (rank : 8)
Query Neighborhood Hits	188	Target Neighborhood Hits	41	Shared Neighborhood Hits	16
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

E2F1_MOUSE
NC score	0.837497 (rank : 11)	θ value	2.20094e-22 (rank : 11)
Query Neighborhood Hits	188	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	Q61501, Q80VZ3	Gene names	E2f1
Domain Architecture
Description	Transcription factor E2F1 (E2F-1).

TDP1_MOUSE
NC score	0.139445 (rank : 12)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q08639	Gene names	Tfdp1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1).

TDP1_HUMAN
NC score	0.136925 (rank : 13)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	188	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q14186, Q8IZL5	Gene names	TFDP1, DP1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1) (DRTF1).

TDP2_HUMAN
NC score	0.108149 (rank : 14)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	188	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

MDC1_HUMAN
NC score	0.086564 (rank : 15)	θ value	0.0148317 (rank : 13)
Query Neighborhood Hits	188	Target Neighborhood Hits	1446	Shared Neighborhood Hits	91
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

DOT1L_HUMAN
NC score	0.084343 (rank : 16)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	188	Target Neighborhood Hits	660	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PI5PA_HUMAN
NC score	0.077891 (rank : 17)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	188	Target Neighborhood Hits	749	Shared Neighborhood Hits	86
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MAGE1_HUMAN
NC score	0.077546 (rank : 18)	θ value	0.00134147 (rank : 12)
Query Neighborhood Hits	188	Target Neighborhood Hits	1389	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MUC7_HUMAN
NC score	0.073458 (rank : 19)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	188	Target Neighborhood Hits	538	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NACAM_MOUSE
NC score	0.071170 (rank : 20)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	188	Target Neighborhood Hits	1866	Shared Neighborhood Hits	111
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NU214_HUMAN
NC score	0.067410 (rank : 21)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	188	Target Neighborhood Hits	657	Shared Neighborhood Hits	50
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

MYH8_HUMAN
NC score	0.066756 (rank : 22)	θ value	0.0431538 (rank : 19)
Query Neighborhood Hits	188	Target Neighborhood Hits	1610	Shared Neighborhood Hits	45
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
NC score	0.066462 (rank : 23)	θ value	0.0431538 (rank : 20)
Query Neighborhood Hits	188	Target Neighborhood Hits	1600	Shared Neighborhood Hits	40
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH7_HUMAN
NC score	0.066349 (rank : 24)	θ value	0.0252991 (rank : 17)
Query Neighborhood Hits	188	Target Neighborhood Hits	1559	Shared Neighborhood Hits	36
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH6_MOUSE
NC score	0.066247 (rank : 25)	θ value	0.0252991 (rank : 16)
Query Neighborhood Hits	188	Target Neighborhood Hits	1501	Shared Neighborhood Hits	35
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH4_MOUSE
NC score	0.065872 (rank : 26)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	188	Target Neighborhood Hits	1476	Shared Neighborhood Hits	41
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH1_HUMAN
NC score	0.065719 (rank : 27)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	188	Target Neighborhood Hits	1478	Shared Neighborhood Hits	40
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH6_HUMAN
NC score	0.065161 (rank : 28)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	188	Target Neighborhood Hits	1426	Shared Neighborhood Hits	35
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH1_MOUSE
NC score	0.065035 (rank : 29)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	188	Target Neighborhood Hits	1461	Shared Neighborhood Hits	40
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MUC1_HUMAN
NC score	0.064391 (rank : 30)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	188	Target Neighborhood Hits	975	Shared Neighborhood Hits	86
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MYH4_HUMAN
NC score	0.063864 (rank : 31)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	188	Target Neighborhood Hits	1377	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH2_HUMAN
NC score	0.062823 (rank : 32)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	188	Target Neighborhood Hits	1491	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH13_HUMAN
NC score	0.061634 (rank : 33)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	188	Target Neighborhood Hits	1504	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

SYNJ1_MOUSE
NC score	0.061617 (rank : 34)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	188	Target Neighborhood Hits	516	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

MDC1_MOUSE
NC score	0.061528 (rank : 35)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	188	Target Neighborhood Hits	998	Shared Neighborhood Hits	77
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SYNJ1_HUMAN
NC score	0.060533 (rank : 36)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	188	Target Neighborhood Hits	498	Shared Neighborhood Hits	49
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SON_HUMAN
NC score	0.059298 (rank : 37)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	188	Target Neighborhood Hits	1568	Shared Neighborhood Hits	103
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MLL3_HUMAN
NC score	0.058525 (rank : 38)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	188	Target Neighborhood Hits	1644	Shared Neighborhood Hits	95
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MNT_HUMAN
NC score	0.058497 (rank : 39)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	188	Target Neighborhood Hits	496	Shared Neighborhood Hits	47
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PI5PA_MOUSE
NC score	0.058379 (rank : 40)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	188	Target Neighborhood Hits	331	Shared Neighborhood Hits	33
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

NCOA6_MOUSE
NC score	0.058133 (rank : 41)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	188	Target Neighborhood Hits	1076	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MYH3_HUMAN
NC score	0.057825 (rank : 42)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	188	Target Neighborhood Hits	1660	Shared Neighborhood Hits	37
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NCOA6_HUMAN
NC score	0.057486 (rank : 43)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	188	Target Neighborhood Hits	1202	Shared Neighborhood Hits	91
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

URFB1_HUMAN
NC score	0.057297 (rank : 44)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	188	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

CK024_HUMAN
NC score	0.057115 (rank : 45)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	188	Target Neighborhood Hits	408	Shared Neighborhood Hits	55
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

MYO15_HUMAN
NC score	0.056666 (rank : 46)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	188	Target Neighborhood Hits	671	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

ZN638_HUMAN
NC score	0.056614 (rank : 47)	θ value	0.0961366 (rank : 22)
Query Neighborhood Hits	188	Target Neighborhood Hits	343	Shared Neighborhood Hits	24
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

IRS2_HUMAN
NC score	0.056533 (rank : 48)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

OGFR_HUMAN
NC score	0.056000 (rank : 49)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	188	Target Neighborhood Hits	1582	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TAF4_HUMAN
NC score	0.055646 (rank : 50)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	188	Target Neighborhood Hits	687	Shared Neighborhood Hits	52
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

BAT2_HUMAN
NC score	0.055365 (rank : 51)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	188	Target Neighborhood Hits	931	Shared Neighborhood Hits	73
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CBP_MOUSE
NC score	0.054594 (rank : 52)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	188	Target Neighborhood Hits	1051	Shared Neighborhood Hits	77
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MYO15_MOUSE
NC score	0.053808 (rank : 53)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	188	Target Neighborhood Hits	467	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SAPS1_HUMAN
NC score	0.052945 (rank : 54)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	188	Target Neighborhood Hits	704	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CO039_MOUSE
NC score	0.052930 (rank : 55)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	55
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

PPRB_MOUSE
NC score	0.051742 (rank : 56)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	188	Target Neighborhood Hits	354	Shared Neighborhood Hits	31
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RAPH1_HUMAN
NC score	0.051560 (rank : 57)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	188	Target Neighborhood Hits	593	Shared Neighborhood Hits	50
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SRRM2_HUMAN
NC score	0.051194 (rank : 58)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	188	Target Neighborhood Hits	1296	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

IRS2_MOUSE
NC score	0.051162 (rank : 59)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	188	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

ARMX2_MOUSE
NC score	0.048704 (rank : 60)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	188	Target Neighborhood Hits	349	Shared Neighborhood Hits	53
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

MAVS_HUMAN
NC score	0.048454 (rank : 61)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	188	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

PELP1_MOUSE
NC score	0.048413 (rank : 62)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	188	Target Neighborhood Hits	709	Shared Neighborhood Hits	61
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

TARA_HUMAN
NC score	0.047347 (rank : 63)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	188	Target Neighborhood Hits	1626	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SYNPO_HUMAN
NC score	0.047238 (rank : 64)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	188	Target Neighborhood Hits	281	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

MLL2_HUMAN
NC score	0.046177 (rank : 65)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	188	Target Neighborhood Hits	1788	Shared Neighborhood Hits	86
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUC2_HUMAN
NC score	0.045655 (rank : 66)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	188	Target Neighborhood Hits	906	Shared Neighborhood Hits	54
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

AP180_HUMAN
NC score	0.044406 (rank : 67)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	188	Target Neighborhood Hits	183	Shared Neighborhood Hits	24
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

PCLO_HUMAN
NC score	0.043943 (rank : 68)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	188	Target Neighborhood Hits	2046	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

AMOT_HUMAN
NC score	0.043914 (rank : 69)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	188	Target Neighborhood Hits	712	Shared Neighborhood Hits	47
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

CNOT3_HUMAN
NC score	0.043664 (rank : 70)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	188	Target Neighborhood Hits	425	Shared Neighborhood Hits	37
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

FMNL_MOUSE
NC score	0.043573 (rank : 71)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	188	Target Neighborhood Hits	428	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FMNL_HUMAN
NC score	0.043432 (rank : 72)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	188	Target Neighborhood Hits	529	Shared Neighborhood Hits	46
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

TACC3_HUMAN
NC score	0.042547 (rank : 73)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	188	Target Neighborhood Hits	779	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

GCNL2_HUMAN
NC score	0.041645 (rank : 74)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	188	Target Neighborhood Hits	159	Shared Neighborhood Hits	12
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

SNPC4_HUMAN
NC score	0.041421 (rank : 75)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	188	Target Neighborhood Hits	589	Shared Neighborhood Hits	62
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

MLL4_HUMAN
NC score	0.040819 (rank : 76)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	188	Target Neighborhood Hits	722	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CO039_HUMAN
NC score	0.040381 (rank : 77)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	188	Target Neighborhood Hits	264	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

SMR1_MOUSE
NC score	0.040114 (rank : 78)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	188	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

TAF10_HUMAN
NC score	0.040012 (rank : 79)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	188	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q12962, O00703, Q13175	Gene names	TAF10, TAF2H, TAFII30
Domain Architecture
Description	Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) (STAF28).

PGCA_HUMAN
NC score	0.039681 (rank : 80)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	188	Target Neighborhood Hits	821	Shared Neighborhood Hits	54
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

AKTS1_MOUSE
NC score	0.038759 (rank : 81)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	188	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1F4	Gene names	Akt1s1, Pras
Domain Architecture	No domain graphic available
Description	Proline-rich AKT1 substrate 1 (Proline-rich AKT substrate).

CN155_HUMAN
NC score	0.038701 (rank : 82)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	188	Target Neighborhood Hits	385	Shared Neighborhood Hits	35
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CO3A1_HUMAN
NC score	0.038635 (rank : 83)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	188	Target Neighborhood Hits	452	Shared Neighborhood Hits	32
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

K1802_MOUSE
NC score	0.038488 (rank : 84)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	188	Target Neighborhood Hits	1596	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PGCA_MOUSE
NC score	0.038107 (rank : 85)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	188	Target Neighborhood Hits	643	Shared Neighborhood Hits	37
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

CS007_MOUSE
NC score	0.037974 (rank : 86)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	188	Target Neighborhood Hits	464	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

MINT_MOUSE
NC score	0.037196 (rank : 87)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	188	Target Neighborhood Hits	1514	Shared Neighborhood Hits	88
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

WBS14_HUMAN
NC score	0.037142 (rank : 88)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	188	Target Neighborhood Hits	273	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

CO3A1_MOUSE
NC score	0.037023 (rank : 89)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	188	Target Neighborhood Hits	466	Shared Neighborhood Hits	32
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CS007_HUMAN
NC score	0.036872 (rank : 90)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	188	Target Neighborhood Hits	401	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

HUWE1_MOUSE
NC score	0.036816 (rank : 91)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	188	Target Neighborhood Hits	406	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HSF1_MOUSE
NC score	0.036239 (rank : 92)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	188	Target Neighborhood Hits	267	Shared Neighborhood Hits	29
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

FSBP_MOUSE
NC score	0.036077 (rank : 93)	θ value	0.813845 (rank : 52)
Query Neighborhood Hits	188	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BKE5, Q8BJX8	Gene names	Fsbp
Domain Architecture	No domain graphic available
Description	Fibrinogen silencer-binding protein.

MAGD4_HUMAN
NC score	0.035672 (rank : 94)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	188	Target Neighborhood Hits	338	Shared Neighborhood Hits	50
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

HUWE1_HUMAN
NC score	0.035437 (rank : 95)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	188	Target Neighborhood Hits	443	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

PO121_HUMAN
NC score	0.035406 (rank : 96)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	188	Target Neighborhood Hits	344	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

CE152_HUMAN
NC score	0.035198 (rank : 97)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	188	Target Neighborhood Hits	976	Shared Neighborhood Hits	28
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CYLN2_MOUSE
NC score	0.034271 (rank : 98)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	188	Target Neighborhood Hits	1002	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

PCX3_MOUSE
NC score	0.033884 (rank : 99)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	188	Target Neighborhood Hits	134	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

SYNP2_MOUSE
NC score	0.033630 (rank : 100)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	188	Target Neighborhood Hits	252	Shared Neighborhood Hits	20
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

PHC1_HUMAN
NC score	0.033433 (rank : 101)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

CYLN2_HUMAN
NC score	0.032711 (rank : 102)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	188	Target Neighborhood Hits	1004	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

TGON2_HUMAN
NC score	0.032179 (rank : 103)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	188	Target Neighborhood Hits	1037	Shared Neighborhood Hits	50
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CO1A2_HUMAN
NC score	0.031899 (rank : 104)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	188	Target Neighborhood Hits	329	Shared Neighborhood Hits	20
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

ZC3H6_MOUSE
NC score	0.031524 (rank : 105)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	188	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CO1A1_HUMAN
NC score	0.031361 (rank : 106)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	188	Target Neighborhood Hits	475	Shared Neighborhood Hits	34
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

TAF6_HUMAN
NC score	0.030990 (rank : 107)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	188	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

SYNP2_HUMAN
NC score	0.030468 (rank : 108)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	188	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

ATX1_MOUSE
NC score	0.030190 (rank : 109)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	188	Target Neighborhood Hits	264	Shared Neighborhood Hits	27
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

NCOR2_MOUSE
NC score	0.029663 (rank : 110)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	188	Target Neighborhood Hits	790	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

CK5P2_MOUSE
NC score	0.029139 (rank : 111)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	188	Target Neighborhood Hits	1151	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

HCN2_HUMAN
NC score	0.028947 (rank : 112)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	188	Target Neighborhood Hits	369	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CO2A1_MOUSE
NC score	0.028861 (rank : 113)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	188	Target Neighborhood Hits	483	Shared Neighborhood Hits	30
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CRTC1_HUMAN
NC score	0.028616 (rank : 114)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	188	Target Neighborhood Hits	319	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ARMX2_HUMAN
NC score	0.028511 (rank : 115)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	188	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

PCNT_HUMAN
NC score	0.028396 (rank : 116)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	188	Target Neighborhood Hits	1551	Shared Neighborhood Hits	41
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

NF2L1_MOUSE
NC score	0.028280 (rank : 117)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	188	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

RBM12_MOUSE
NC score	0.028262 (rank : 118)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	188	Target Neighborhood Hits	313	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

NF2L1_HUMAN
NC score	0.028193 (rank : 119)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	188	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

RCOR2_MOUSE
NC score	0.028009 (rank : 120)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	188	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

HCN2_MOUSE
NC score	0.027586 (rank : 121)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	188	Target Neighborhood Hits	278	Shared Neighborhood Hits	28
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

SOX13_HUMAN
NC score	0.027090 (rank : 122)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	188	Target Neighborhood Hits	464	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ZFYV9_HUMAN
NC score	0.026716 (rank : 123)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	188	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

3BP1_HUMAN
NC score	0.025701 (rank : 124)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	188	Target Neighborhood Hits	376	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

EP400_HUMAN
NC score	0.025677 (rank : 125)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	188	Target Neighborhood Hits	556	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

TISD_MOUSE
NC score	0.025641 (rank : 126)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	188	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

IL2RB_MOUSE
NC score	0.025568 (rank : 127)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	188	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

GA2L3_HUMAN
NC score	0.025092 (rank : 128)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	188	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

CR025_HUMAN
NC score	0.024929 (rank : 129)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	188	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q96B23, Q5XG78, Q6N058, Q86TB5, Q8TCQ5	Gene names	C18orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25.

WWP1_HUMAN
NC score	0.024636 (rank : 130)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

RCOR2_HUMAN
NC score	0.023786 (rank : 131)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	188	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

SETD2_HUMAN
NC score	0.023614 (rank : 132)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	188	Target Neighborhood Hits	412	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SFPQ_MOUSE
NC score	0.023576 (rank : 133)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	188	Target Neighborhood Hits	958	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SHB_HUMAN
NC score	0.022850 (rank : 134)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	188	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

COBA2_HUMAN
NC score	0.022613 (rank : 135)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	188	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

FHOD1_HUMAN
NC score	0.022604 (rank : 136)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	188	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

YTHD1_HUMAN
NC score	0.022511 (rank : 137)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

MUC15_MOUSE
NC score	0.022472 (rank : 138)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	188	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C6Z1, Q3UQC4, Q6XYQ9, Q7TMH6, Q8CE82	Gene names	Muc15
Domain Architecture	No domain graphic available
Description	Mucin-15 precursor.

COBA2_MOUSE
NC score	0.022301 (rank : 139)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	188	Target Neighborhood Hits	501	Shared Neighborhood Hits	33
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

UBE4B_HUMAN
NC score	0.022283 (rank : 140)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	188	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

K2002_HUMAN
NC score	0.021901 (rank : 141)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	188	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H792, Q6ZS78, Q8NCM3	Gene names	KIAA2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

KCNB2_HUMAN
NC score	0.021779 (rank : 142)	θ value	0.0431538 (rank : 18)
Query Neighborhood Hits	188	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

CO9A3_HUMAN
NC score	0.021570 (rank : 143)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	188	Target Neighborhood Hits	361	Shared Neighborhood Hits	20
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

TR10C_HUMAN
NC score	0.021025 (rank : 144)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	188	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

ODO2_MOUSE
NC score	0.020264 (rank : 145)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

I12R2_HUMAN
NC score	0.018627 (rank : 146)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	188	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

CENPU_HUMAN
NC score	0.018437 (rank : 147)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	188	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

PLXB1_HUMAN
NC score	0.018215 (rank : 148)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	188	Target Neighborhood Hits	360	Shared Neighborhood Hits	38
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

CENG1_MOUSE
NC score	0.017213 (rank : 149)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	188	Target Neighborhood Hits	531	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

KCNC3_MOUSE
NC score	0.016646 (rank : 150)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	188	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

AIRE_HUMAN
NC score	0.016481 (rank : 151)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	188	Target Neighborhood Hits	144	Shared Neighborhood Hits	11
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

ZMYM3_HUMAN
NC score	0.016315 (rank : 152)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

SHAN1_HUMAN
NC score	0.016271 (rank : 153)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	188	Target Neighborhood Hits	1041	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

WNK1_MOUSE
NC score	0.015826 (rank : 154)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	188	Target Neighborhood Hits	1179	Shared Neighborhood Hits	49
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

WNK1_HUMAN
NC score	0.015769 (rank : 155)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	188	Target Neighborhood Hits	1158	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

LSP1_MOUSE
NC score	0.015274 (rank : 156)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	188	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

WNK4_HUMAN
NC score	0.014500 (rank : 157)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	188	Target Neighborhood Hits	1043	Shared Neighborhood Hits	37
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

PHAR3_HUMAN
NC score	0.013990 (rank : 158)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	188	Target Neighborhood Hits	169	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

GNDS_HUMAN
NC score	0.013101 (rank : 159)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	188	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

ZEP1_MOUSE
NC score	0.013039 (rank : 160)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	188	Target Neighborhood Hits	1063	Shared Neighborhood Hits	48
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

LAMB3_MOUSE
NC score	0.012325 (rank : 161)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	188	Target Neighborhood Hits	444	Shared Neighborhood Hits	22
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

FOG1_MOUSE
NC score	0.012264 (rank : 162)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	188	Target Neighborhood Hits	1237	Shared Neighborhood Hits	65
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

UBXD2_MOUSE
NC score	0.011930 (rank : 163)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	188	Target Neighborhood Hits	183	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

HRSL5_HUMAN
NC score	0.011435 (rank : 164)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	188	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KN8	Gene names	HRASLS5, HRLP5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

DBP_MOUSE
NC score	0.011333 (rank : 165)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	188	Target Neighborhood Hits	137	Shared Neighborhood Hits	6
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

STAR8_HUMAN
NC score	0.011149 (rank : 166)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	188	Target Neighborhood Hits	216	Shared Neighborhood Hits	24
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

SPEG_MOUSE
NC score	0.011131 (rank : 167)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	188	Target Neighborhood Hits	1959	Shared Neighborhood Hits	75
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SALL3_HUMAN
NC score	0.010318 (rank : 168)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	188	Target Neighborhood Hits	1066	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

PRDM2_HUMAN
NC score	0.010281 (rank : 169)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	188	Target Neighborhood Hits	1135	Shared Neighborhood Hits	42
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

FBXL5_MOUSE
NC score	0.008956 (rank : 170)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	188	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

LTB1L_MOUSE
NC score	0.008749 (rank : 171)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	188	Target Neighborhood Hits	514	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.008565 (rank : 172)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	188	Target Neighborhood Hits	479	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.008518 (rank : 173)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	188	Target Neighborhood Hits	553	Shared Neighborhood Hits	23
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

KGP2_HUMAN
NC score	0.008228 (rank : 174)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	188	Target Neighborhood Hits	1023	Shared Neighborhood Hits	27
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

ST2B1_HUMAN
NC score	0.008139 (rank : 175)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	188	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

LTB1S_HUMAN
NC score	0.007996 (rank : 176)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	188	Target Neighborhood Hits	502	Shared Neighborhood Hits	18
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

GBX1_HUMAN
NC score	0.007956 (rank : 177)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	188	Target Neighborhood Hits	334	Shared Neighborhood Hits	4
SwissProt Accessions	Q14549	Gene names	GBX1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

PI4KB_MOUSE
NC score	0.007955 (rank : 178)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	188	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

SOX3_HUMAN
NC score	0.007135 (rank : 179)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	188	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

TNKS1_HUMAN
NC score	0.006941 (rank : 180)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	188	Target Neighborhood Hits	477	Shared Neighborhood Hits	17
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

KGP2_MOUSE
NC score	0.006389 (rank : 181)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	188	Target Neighborhood Hits	1029	Shared Neighborhood Hits	26
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

IRAK1_MOUSE
NC score	0.005691 (rank : 182)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	188	Target Neighborhood Hits	784	Shared Neighborhood Hits	15
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

ADA12_HUMAN
NC score	0.004766 (rank : 183)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	188	Target Neighborhood Hits	224	Shared Neighborhood Hits	8
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

MK07_MOUSE
NC score	0.004396 (rank : 184)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	188	Target Neighborhood Hits	1054	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

FOXF2_HUMAN
NC score	0.004050 (rank : 185)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	188	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

FOXGB_HUMAN
NC score	0.003921 (rank : 186)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	188	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

PGLB_HUMAN
NC score	0.003730 (rank : 187)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	188	Target Neighborhood Hits	250	Shared Neighborhood Hits	2
SwissProt Accessions	Q99645, Q8NEJ5	Gene names	DSPG3, PGLB
Domain Architecture
Description	Dermatan sulfate proteoglycan 3 precursor (Epiphycan) (Small chondroitin/dermatan sulfate proteoglycan) (Proteoglycan-Lb) (PG-Lb).

SBK1_MOUSE
NC score	0.002865 (rank : 188)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	188	Target Neighborhood Hits	824	Shared Neighborhood Hits	14
SwissProt Accessions	Q8QZX0	Gene names	Sbk1, Sbk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1).

PTPRJ_HUMAN
NC score	0.002580 (rank : 189)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	188	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

ZN142_HUMAN
NC score	0.002532 (rank : 190)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	188	Target Neighborhood Hits	1007	Shared Neighborhood Hits	41
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

MTR1L_HUMAN
NC score	0.001061 (rank : 191)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	188	Target Neighborhood Hits	1180	Shared Neighborhood Hits	30
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

EGR4_MOUSE
NC score	-0.000146 (rank : 192)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	188	Target Neighborhood Hits	710	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WUF2	Gene names	Egr4
Domain Architecture
Description	Early growth response protein 4 (EGR-4).

TIE1_HUMAN
NC score	-0.000265 (rank : 193)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	188	Target Neighborhood Hits	1241	Shared Neighborhood Hits	19
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MTF1_HUMAN
NC score	-0.000309 (rank : 194)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	188	Target Neighborhood Hits	814	Shared Neighborhood Hits	23
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

KLF3_MOUSE
NC score	-0.000505 (rank : 195)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	188	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	Q60980	Gene names	Klf3, Bklf
Domain Architecture
Description	Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2).

SCRT1_MOUSE
NC score	-0.000749 (rank : 196)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	188	Target Neighborhood Hits	703	Shared Neighborhood Hits	11
SwissProt Accessions	Q99M85	Gene names	Scrt1
Domain Architecture	No domain graphic available
Description	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (Scratch 1) (SCRT) (mScrt).