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Network neighborhood for query Sequence : ST2B1_HUMAN

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ST2B1_HUMAN
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ST2B1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	57
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ST2B1_MOUSE
θ value	4.88915e-147 (rank : 2)	NC score	0.997583 (rank : 2)
Query Neighborhood Hits	57	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ST2A1_MOUSE
θ value	6.73165e-80 (rank : 3)	NC score	0.986875 (rank : 4)
Query Neighborhood Hits	57	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P52843	Gene names	Sult2a1, Sta1
Domain Architecture	No domain graphic available
Description	Bile salt sulfotransferase 1 (EC 2.8.2.14) (Hydroxysteroid sulfotransferase) (ST).

ST2A2_MOUSE
θ value	4.36332e-79 (rank : 4)	NC score	0.986356 (rank : 5)
Query Neighborhood Hits	57	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P50236	Gene names	Sult2a2, Sta2, Sth2
Domain Architecture
Description	Bile salt sulfotransferase 2 (EC 2.8.2.14) (Hydroxysteroid sulfotransferase) (ST).

ST2A1_HUMAN
θ value	2.82823e-78 (rank : 5)	NC score	0.987312 (rank : 3)
Query Neighborhood Hits	57	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q06520	Gene names	SULT2A1, HST, STD
Domain Architecture
Description	Bile salt sulfotransferase (EC 2.8.2.14) (Hydroxysteroid Sulfotransferase) (HST) (Dehydroepiandrosterone sulfotransferase) (DHEA-ST) (ST2) (ST2A3).

ST3A1_MOUSE
θ value	3.59435e-57 (rank : 6)	NC score	0.980312 (rank : 6)
Query Neighborhood Hits	57	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O35403	Gene names	Sult3a1, St3a1
Domain Architecture	No domain graphic available
Description	Amine sulfotransferase (EC 2.8.2.3) (Sulfotransferase 3A1) (SULT-X2).

ST1A3_HUMAN
θ value	4.69435e-57 (rank : 7)	NC score	0.966616 (rank : 17)
Query Neighborhood Hits	57	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

ST1B1_MOUSE
θ value	4.69435e-57 (rank : 8)	NC score	0.970855 (rank : 8)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QWG7, Q8C301, Q9Z2T0	Gene names	Sult1b1
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 1B member 1 (EC 2.8.2.-) (Sulfotransferase 1B1) (DOPA/tyrosine sulfotransferase).

ST1C1_MOUSE
θ value	4.69435e-57 (rank : 9)	NC score	0.969745 (rank : 9)
Query Neighborhood Hits	57	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	Q80VR3, O70262	Gene names	Sult1c1, Sult1a2
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (Phenol sulfotransferase).

ST1C3_HUMAN
θ value	1.36585e-56 (rank : 10)	NC score	0.969499 (rank : 11)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q6IMI6, Q6IMI5	Gene names	SULT1C3
Domain Architecture	No domain graphic available
Description	Putative sulfotransferase 1C3 (EC 2.8.2.-).

ST1A1_HUMAN
θ value	1.97229e-55 (rank : 11)	NC score	0.966070 (rank : 18)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P50225, Q2NL71, Q86U58, Q92818, Q9BVU6, Q9UGG7	Gene names	SULT1A1, STP, STP1
Domain Architecture
Description	Sulfotransferase 1A1 (EC 2.8.2.1) (Aryl sulfotransferase 1) (Phenol sulfotransferase 1) (Phenol-sulfating phenol sulfotransferase 1) (P- PST 1) (Thermostable phenol sulfotransferase) (Ts-PST) (HAST1/HAST2) (ST1A3).

ST1B1_HUMAN
θ value	4.39379e-55 (rank : 12)	NC score	0.968860 (rank : 14)
Query Neighborhood Hits	57	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O43704, O15497, Q96FI1, Q9UK34	Gene names	SULT1B1, ST1B2, SULT1B2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 1B member 1 (EC 2.8.2.-) (Sulfotransferase 1B2) (Thyroid hormone sulfotransferase).

ST1A1_MOUSE
θ value	1.2784e-54 (rank : 13)	NC score	0.969438 (rank : 12)
Query Neighborhood Hits	57	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P52840	Gene names	Sult1a1, St1a1, Stp, Stp1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1A1 (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Sulfokinase) (Phenol/aryl sulfotransferase) (mSTp1) (ST1A4).

ST1C2_MOUSE
θ value	1.2784e-54 (rank : 14)	NC score	0.969317 (rank : 13)
Query Neighborhood Hits	57	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D939, Q3UNA9, Q8R210	Gene names	Sult1c2, Sult1c1
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-).

ST1C1_HUMAN
θ value	2.18062e-54 (rank : 15)	NC score	0.969521 (rank : 10)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	O00338	Gene names	SULT1C1
Domain Architecture
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (SULT1C#1) (ST1C2) (humSULTC2).

ST1C2_HUMAN
θ value	8.28633e-54 (rank : 16)	NC score	0.970905 (rank : 7)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	O75897, Q53S63	Gene names	SULT1C2
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-) (SULT1C) (SULT1C#2).

ST1E1_HUMAN
θ value	3.1488e-53 (rank : 17)	NC score	0.968227 (rank : 16)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P49888, Q8N6X5	Gene names	SULT1E1, STE
Domain Architecture
Description	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen- preferring) (EST-1).

ST1A2_HUMAN
θ value	5.37103e-53 (rank : 18)	NC score	0.966029 (rank : 19)
Query Neighborhood Hits	57	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P50226, P78393	Gene names	SULT1A2, STP2
Domain Architecture
Description	Sulfotransferase 1A2 (EC 2.8.2.1) (Aryl sulfotransferase 2) (Phenol sulfotransferase 2) (Phenol-sulfating phenol sulfotransferase 2) (P- PST 2) (ST1A2).

ST1E1_MOUSE
θ value	7.75577e-52 (rank : 19)	NC score	0.968818 (rank : 15)
Query Neighborhood Hits	57	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P49891	Gene names	Sult1e1, Ste
Domain Architecture
Description	Estrogen sulfotransferase, testis isoform (EC 2.8.2.4) (Sulfotransferase, estrogen-preferring).

ST4A1_MOUSE
θ value	2.50655e-34 (rank : 20)	NC score	0.944389 (rank : 21)
Query Neighborhood Hits	57	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	P63046, O88872, Q3TXY5, Q91XS5, Q9CWY7, Q9DC97	Gene names	Sult4a1, Sultx3
Domain Architecture	No domain graphic available
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (mBR-STL) (Nervous system sulfotransferase) (NST).

ST4A1_HUMAN
θ value	5.584e-34 (rank : 21)	NC score	0.943717 (rank : 22)
Query Neighborhood Hits	57	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BR01, O43728	Gene names	SULT4A1, SULTX3
Domain Architecture
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST).

ST6B1_HUMAN
θ value	1.16434e-31 (rank : 22)	NC score	0.958906 (rank : 20)
Query Neighborhood Hits	57	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	Q6IMI4	Gene names	SULT6B1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 6B1 (EC 2.8.2.-).

OST6_MOUSE
θ value	0.00390308 (rank : 23)	NC score	0.077327 (rank : 23)
Query Neighborhood Hits	57	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST6_HUMAN
θ value	0.00665767 (rank : 24)	NC score	0.074574 (rank : 24)
Query Neighborhood Hits	57	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OGFR_HUMAN
θ value	0.0431538 (rank : 25)	NC score	0.012608 (rank : 34)
Query Neighborhood Hits	57	Target Neighborhood Hits	1582	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OST3A_MOUSE
θ value	0.365318 (rank : 26)	NC score	0.064199 (rank : 25)
Query Neighborhood Hits	57	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3B_MOUSE
θ value	0.365318 (rank : 27)	NC score	0.064196 (rank : 26)
Query Neighborhood Hits	57	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

JIP3_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.008829 (rank : 36)
Query Neighborhood Hits	57	Target Neighborhood Hits	1039	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

EVL_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.016086 (rank : 32)
Query Neighborhood Hits	57	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

NANO3_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.018453 (rank : 31)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P60323	Gene names	NANOS3, NOS3
Domain Architecture	No domain graphic available
Description	Nanos homolog 3.

OST3A_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.056260 (rank : 28)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3B_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.056429 (rank : 27)
Query Neighborhood Hits	57	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

RGS3_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.005148 (rank : 46)
Query Neighborhood Hits	57	Target Neighborhood Hits	1375	Shared Neighborhood Hits	17
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TBCD2_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.011507 (rank : 35)
Query Neighborhood Hits	57	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

SYTL1_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.007814 (rank : 40)
Query Neighborhood Hits	57	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

TRI56_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.008268 (rank : 37)
Query Neighborhood Hits	57	Target Neighborhood Hits	339	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

SON_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.003357 (rank : 50)
Query Neighborhood Hits	57	Target Neighborhood Hits	1568	Shared Neighborhood Hits	14
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CLCN1_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.005612 (rank : 45)
Query Neighborhood Hits	57	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

E2F4_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.008139 (rank : 38)
Query Neighborhood Hits	57	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

OST2_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.047901 (rank : 30)
Query Neighborhood Hits	57	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

PSL1_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.007426 (rank : 41)
Query Neighborhood Hits	57	Target Neighborhood Hits	650	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

BRPF3_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.004802 (rank : 47)
Query Neighborhood Hits	57	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CBLC_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.006318 (rank : 44)
Query Neighborhood Hits	57	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

FGD1_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.004187 (rank : 49)
Query Neighborhood Hits	57	Target Neighborhood Hits	367	Shared Neighborhood Hits	12
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

CO039_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.007857 (rank : 39)
Query Neighborhood Hits	57	Target Neighborhood Hits	445	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

DNM1L_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.004507 (rank : 48)
Query Neighborhood Hits	57	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

EVL_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.012839 (rank : 33)
Query Neighborhood Hits	57	Target Neighborhood Hits	260	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

IWS1_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.001382 (rank : 52)
Query Neighborhood Hits	57	Target Neighborhood Hits	1258	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1802_MOUSE
θ value	6.88961 (rank : 49)	NC score	0.000471 (rank : 57)
Query Neighborhood Hits	57	Target Neighborhood Hits	1596	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

OST2_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.050471 (rank : 29)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

PRGC2_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.006846 (rank : 43)
Query Neighborhood Hits	57	Target Neighborhood Hits	272	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

ASPP1_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.000700 (rank : 56)
Query Neighborhood Hits	57	Target Neighborhood Hits	1244	Shared Neighborhood Hits	15
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CAC1B_MOUSE
θ value	8.99809 (rank : 53)	NC score	0.001247 (rank : 54)
Query Neighborhood Hits	57	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CN101_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.007087 (rank : 42)
Query Neighborhood Hits	57	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX78, Q86XE1	Gene names	C14orf101
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf101.

COKA1_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.001231 (rank : 55)
Query Neighborhood Hits	57	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

DZIP1_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.002755 (rank : 51)
Query Neighborhood Hits	57	Target Neighborhood Hits	675	Shared Neighborhood Hits	4
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

MDC1_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.001382 (rank : 53)
Query Neighborhood Hits	57	Target Neighborhood Hits	1446	Shared Neighborhood Hits	16
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

Hits sorted by NC score

ST2B1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	57
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ST2B1_MOUSE
NC score	0.997583 (rank : 2)	θ value	4.88915e-147 (rank : 2)
Query Neighborhood Hits	57	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ST2A1_HUMAN
NC score	0.987312 (rank : 3)	θ value	2.82823e-78 (rank : 5)
Query Neighborhood Hits	57	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q06520	Gene names	SULT2A1, HST, STD
Domain Architecture
Description	Bile salt sulfotransferase (EC 2.8.2.14) (Hydroxysteroid Sulfotransferase) (HST) (Dehydroepiandrosterone sulfotransferase) (DHEA-ST) (ST2) (ST2A3).

ST2A1_MOUSE
NC score	0.986875 (rank : 4)	θ value	6.73165e-80 (rank : 3)
Query Neighborhood Hits	57	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P52843	Gene names	Sult2a1, Sta1
Domain Architecture	No domain graphic available
Description	Bile salt sulfotransferase 1 (EC 2.8.2.14) (Hydroxysteroid sulfotransferase) (ST).

ST2A2_MOUSE
NC score	0.986356 (rank : 5)	θ value	4.36332e-79 (rank : 4)
Query Neighborhood Hits	57	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P50236	Gene names	Sult2a2, Sta2, Sth2
Domain Architecture
Description	Bile salt sulfotransferase 2 (EC 2.8.2.14) (Hydroxysteroid sulfotransferase) (ST).

ST3A1_MOUSE
NC score	0.980312 (rank : 6)	θ value	3.59435e-57 (rank : 6)
Query Neighborhood Hits	57	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O35403	Gene names	Sult3a1, St3a1
Domain Architecture	No domain graphic available
Description	Amine sulfotransferase (EC 2.8.2.3) (Sulfotransferase 3A1) (SULT-X2).

ST1C2_HUMAN
NC score	0.970905 (rank : 7)	θ value	8.28633e-54 (rank : 16)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	O75897, Q53S63	Gene names	SULT1C2
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-) (SULT1C) (SULT1C#2).

ST1B1_MOUSE
NC score	0.970855 (rank : 8)	θ value	4.69435e-57 (rank : 8)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QWG7, Q8C301, Q9Z2T0	Gene names	Sult1b1
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 1B member 1 (EC 2.8.2.-) (Sulfotransferase 1B1) (DOPA/tyrosine sulfotransferase).

ST1C1_MOUSE
NC score	0.969745 (rank : 9)	θ value	4.69435e-57 (rank : 9)
Query Neighborhood Hits	57	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	Q80VR3, O70262	Gene names	Sult1c1, Sult1a2
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (Phenol sulfotransferase).

ST1C1_HUMAN
NC score	0.969521 (rank : 10)	θ value	2.18062e-54 (rank : 15)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	O00338	Gene names	SULT1C1
Domain Architecture
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (SULT1C#1) (ST1C2) (humSULTC2).

ST1C3_HUMAN
NC score	0.969499 (rank : 11)	θ value	1.36585e-56 (rank : 10)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q6IMI6, Q6IMI5	Gene names	SULT1C3
Domain Architecture	No domain graphic available
Description	Putative sulfotransferase 1C3 (EC 2.8.2.-).

ST1A1_MOUSE
NC score	0.969438 (rank : 12)	θ value	1.2784e-54 (rank : 13)
Query Neighborhood Hits	57	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P52840	Gene names	Sult1a1, St1a1, Stp, Stp1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1A1 (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Sulfokinase) (Phenol/aryl sulfotransferase) (mSTp1) (ST1A4).

ST1C2_MOUSE
NC score	0.969317 (rank : 13)	θ value	1.2784e-54 (rank : 14)
Query Neighborhood Hits	57	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D939, Q3UNA9, Q8R210	Gene names	Sult1c2, Sult1c1
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-).

ST1B1_HUMAN
NC score	0.968860 (rank : 14)	θ value	4.39379e-55 (rank : 12)
Query Neighborhood Hits	57	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O43704, O15497, Q96FI1, Q9UK34	Gene names	SULT1B1, ST1B2, SULT1B2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 1B member 1 (EC 2.8.2.-) (Sulfotransferase 1B2) (Thyroid hormone sulfotransferase).

ST1E1_MOUSE
NC score	0.968818 (rank : 15)	θ value	7.75577e-52 (rank : 19)
Query Neighborhood Hits	57	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P49891	Gene names	Sult1e1, Ste
Domain Architecture
Description	Estrogen sulfotransferase, testis isoform (EC 2.8.2.4) (Sulfotransferase, estrogen-preferring).

ST1E1_HUMAN
NC score	0.968227 (rank : 16)	θ value	3.1488e-53 (rank : 17)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P49888, Q8N6X5	Gene names	SULT1E1, STE
Domain Architecture
Description	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen- preferring) (EST-1).

ST1A3_HUMAN
NC score	0.966616 (rank : 17)	θ value	4.69435e-57 (rank : 7)
Query Neighborhood Hits	57	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

ST1A1_HUMAN
NC score	0.966070 (rank : 18)	θ value	1.97229e-55 (rank : 11)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P50225, Q2NL71, Q86U58, Q92818, Q9BVU6, Q9UGG7	Gene names	SULT1A1, STP, STP1
Domain Architecture
Description	Sulfotransferase 1A1 (EC 2.8.2.1) (Aryl sulfotransferase 1) (Phenol sulfotransferase 1) (Phenol-sulfating phenol sulfotransferase 1) (P- PST 1) (Thermostable phenol sulfotransferase) (Ts-PST) (HAST1/HAST2) (ST1A3).

ST1A2_HUMAN
NC score	0.966029 (rank : 19)	θ value	5.37103e-53 (rank : 18)
Query Neighborhood Hits	57	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P50226, P78393	Gene names	SULT1A2, STP2
Domain Architecture
Description	Sulfotransferase 1A2 (EC 2.8.2.1) (Aryl sulfotransferase 2) (Phenol sulfotransferase 2) (Phenol-sulfating phenol sulfotransferase 2) (P- PST 2) (ST1A2).

ST6B1_HUMAN
NC score	0.958906 (rank : 20)	θ value	1.16434e-31 (rank : 22)
Query Neighborhood Hits	57	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	Q6IMI4	Gene names	SULT6B1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 6B1 (EC 2.8.2.-).

ST4A1_MOUSE
NC score	0.944389 (rank : 21)	θ value	2.50655e-34 (rank : 20)
Query Neighborhood Hits	57	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	P63046, O88872, Q3TXY5, Q91XS5, Q9CWY7, Q9DC97	Gene names	Sult4a1, Sultx3
Domain Architecture	No domain graphic available
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (mBR-STL) (Nervous system sulfotransferase) (NST).

ST4A1_HUMAN
NC score	0.943717 (rank : 22)	θ value	5.584e-34 (rank : 21)
Query Neighborhood Hits	57	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BR01, O43728	Gene names	SULT4A1, SULTX3
Domain Architecture
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST).

OST6_MOUSE
NC score	0.077327 (rank : 23)	θ value	0.00390308 (rank : 23)
Query Neighborhood Hits	57	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST6_HUMAN
NC score	0.074574 (rank : 24)	θ value	0.00665767 (rank : 24)
Query Neighborhood Hits	57	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST3A_MOUSE
NC score	0.064199 (rank : 25)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	57	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3B_MOUSE
NC score	0.064196 (rank : 26)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	57	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST3B_HUMAN
NC score	0.056429 (rank : 27)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	57	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST3A_HUMAN
NC score	0.056260 (rank : 28)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST2_HUMAN
NC score	0.050471 (rank : 29)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST2_MOUSE
NC score	0.047901 (rank : 30)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	57	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

NANO3_HUMAN
NC score	0.018453 (rank : 31)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P60323	Gene names	NANOS3, NOS3
Domain Architecture	No domain graphic available
Description	Nanos homolog 3.

EVL_MOUSE
NC score	0.016086 (rank : 32)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	57	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

EVL_HUMAN
NC score	0.012839 (rank : 33)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	57	Target Neighborhood Hits	260	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

OGFR_HUMAN
NC score	0.012608 (rank : 34)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	57	Target Neighborhood Hits	1582	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TBCD2_HUMAN
NC score	0.011507 (rank : 35)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	57	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

JIP3_HUMAN
NC score	0.008829 (rank : 36)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	57	Target Neighborhood Hits	1039	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

TRI56_HUMAN
NC score	0.008268 (rank : 37)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	57	Target Neighborhood Hits	339	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

E2F4_HUMAN
NC score	0.008139 (rank : 38)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	57	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

CO039_MOUSE
NC score	0.007857 (rank : 39)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	57	Target Neighborhood Hits	445	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

SYTL1_HUMAN
NC score	0.007814 (rank : 40)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	57	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

PSL1_HUMAN
NC score	0.007426 (rank : 41)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	57	Target Neighborhood Hits	650	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

CN101_HUMAN
NC score	0.007087 (rank : 42)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	57	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX78, Q86XE1	Gene names	C14orf101
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf101.

PRGC2_HUMAN
NC score	0.006846 (rank : 43)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	57	Target Neighborhood Hits	272	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

CBLC_HUMAN
NC score	0.006318 (rank : 44)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	57	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CLCN1_HUMAN
NC score	0.005612 (rank : 45)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	57	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

RGS3_HUMAN
NC score	0.005148 (rank : 46)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	57	Target Neighborhood Hits	1375	Shared Neighborhood Hits	17
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

BRPF3_HUMAN
NC score	0.004802 (rank : 47)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	57	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

DNM1L_MOUSE
NC score	0.004507 (rank : 48)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	57	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

FGD1_HUMAN
NC score	0.004187 (rank : 49)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	57	Target Neighborhood Hits	367	Shared Neighborhood Hits	12
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SON_HUMAN
NC score	0.003357 (rank : 50)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	57	Target Neighborhood Hits	1568	Shared Neighborhood Hits	14
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DZIP1_HUMAN
NC score	0.002755 (rank : 51)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	57	Target Neighborhood Hits	675	Shared Neighborhood Hits	4
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

IWS1_MOUSE
NC score	0.001382 (rank : 52)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	57	Target Neighborhood Hits	1258	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MDC1_HUMAN
NC score	0.001382 (rank : 53)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	57	Target Neighborhood Hits	1446	Shared Neighborhood Hits	16
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CAC1B_MOUSE
NC score	0.001247 (rank : 54)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	57	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

COKA1_HUMAN
NC score	0.001231 (rank : 55)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	57	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

ASPP1_MOUSE
NC score	0.000700 (rank : 56)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	57	Target Neighborhood Hits	1244	Shared Neighborhood Hits	15
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

K1802_MOUSE
NC score	0.000471 (rank : 57)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	57	Target Neighborhood Hits	1596	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.