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Network neighborhood for query Sequence : E2F6_HUMAN

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E2F6_HUMAN
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

E2F6_HUMAN
θ value	2.0589e-137 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

E2F6_MOUSE
θ value	3.07662e-133 (rank : 2)	NC score	0.997845 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

E2F3_HUMAN
θ value	3.37202e-47 (rank : 3)	NC score	0.942494 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

E2F3_MOUSE
θ value	3.37202e-47 (rank : 4)	NC score	0.941868 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

E2F2_MOUSE
θ value	7.51208e-47 (rank : 5)	NC score	0.941219 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P56931, Q8BID0	Gene names	E2f2
Domain Architecture	No domain graphic available
Description	Transcription factor E2F2 (E2F-2).

E2F2_HUMAN
θ value	2.85459e-46 (rank : 6)	NC score	0.938562 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

E2F1_HUMAN
θ value	8.32485e-38 (rank : 7)	NC score	0.927732 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

E2F1_MOUSE
θ value	9.20422e-37 (rank : 8)	NC score	0.927163 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q61501, Q80VZ3	Gene names	E2f1
Domain Architecture
Description	Transcription factor E2F1 (E2F-1).

E2F5_MOUSE
θ value	1.2049e-28 (rank : 9)	NC score	0.882316 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F5_HUMAN
θ value	2.05525e-28 (rank : 10)	NC score	0.881985 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F4_HUMAN
θ value	1.02001e-27 (rank : 11)	NC score	0.862689 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

TDP1_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.167146 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q14186, Q8IZL5	Gene names	TFDP1, DP1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1) (DRTF1).

TDP1_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.169516 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q08639	Gene names	Tfdp1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1).

TDP2_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.131893 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

MYH3_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.005600 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	1660	Shared Neighborhood Hits	6
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

CN145_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.009811 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	916	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

HS90B_MOUSE
θ value	2.36792 (rank : 17)	NC score	0.017440 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

EXOC3_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.015282 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

RBM19_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.004990 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	331	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

TPPC5_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.021978 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUR0	Gene names	TRAPPC5
Domain Architecture	No domain graphic available
Description	Trafficking protein particle complex subunit 5.

CP045_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.011298 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MC5, O00223, O75769, Q8IZ36, Q96H25	Gene names	C16orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf45.

PAPD1_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.009947 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0D3, Q3UXJ1, Q8C651	Gene names	Papd1
Domain Architecture	No domain graphic available
Description	Poly(A) RNA polymerase, mitochondrial precursor (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase) (PAP-associated domain-containing protein 1).

TPPC5_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.020372 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQA1, Q8BJX6	Gene names	Trappc5
Domain Architecture	No domain graphic available
Description	Trafficking protein particle complex subunit 5.

Hits sorted by NC score

E2F6_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.0589e-137 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	O75461, O60544, Q7Z2H6	Gene names	E2F6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6).

E2F6_MOUSE
NC score	0.997845 (rank : 2)	θ value	3.07662e-133 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

E2F3_HUMAN
NC score	0.942494 (rank : 3)	θ value	3.37202e-47 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

E2F3_MOUSE
NC score	0.941868 (rank : 4)	θ value	3.37202e-47 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

E2F2_MOUSE
NC score	0.941219 (rank : 5)	θ value	7.51208e-47 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P56931, Q8BID0	Gene names	E2f2
Domain Architecture	No domain graphic available
Description	Transcription factor E2F2 (E2F-2).

E2F2_HUMAN
NC score	0.938562 (rank : 6)	θ value	2.85459e-46 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

E2F1_HUMAN
NC score	0.927732 (rank : 7)	θ value	8.32485e-38 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

E2F1_MOUSE
NC score	0.927163 (rank : 8)	θ value	9.20422e-37 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q61501, Q80VZ3	Gene names	E2f1
Domain Architecture
Description	Transcription factor E2F1 (E2F-1).

E2F5_MOUSE
NC score	0.882316 (rank : 9)	θ value	1.2049e-28 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F5_HUMAN
NC score	0.881985 (rank : 10)	θ value	2.05525e-28 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

E2F4_HUMAN
NC score	0.862689 (rank : 11)	θ value	1.02001e-27 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

TDP1_MOUSE
NC score	0.169516 (rank : 12)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q08639	Gene names	Tfdp1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1).

TDP1_HUMAN
NC score	0.167146 (rank : 13)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q14186, Q8IZL5	Gene names	TFDP1, DP1
Domain Architecture
Description	Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1) (DRTF1).

TDP2_HUMAN
NC score	0.131893 (rank : 14)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q14188, Q13331, Q14187, Q6R754, Q8WU88	Gene names	TFDP2, DP2
Domain Architecture
Description	Transcription factor Dp-2 (E2F dimerization partner 2).

TPPC5_HUMAN
NC score	0.021978 (rank : 15)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUR0	Gene names	TRAPPC5
Domain Architecture	No domain graphic available
Description	Trafficking protein particle complex subunit 5.

TPPC5_MOUSE
NC score	0.020372 (rank : 16)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQA1, Q8BJX6	Gene names	Trappc5
Domain Architecture	No domain graphic available
Description	Trafficking protein particle complex subunit 5.

HS90B_MOUSE
NC score	0.017440 (rank : 17)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

EXOC3_MOUSE
NC score	0.015282 (rank : 18)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

CP045_HUMAN
NC score	0.011298 (rank : 19)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MC5, O00223, O75769, Q8IZ36, Q96H25	Gene names	C16orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf45.

PAPD1_MOUSE
NC score	0.009947 (rank : 20)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0D3, Q3UXJ1, Q8C651	Gene names	Papd1
Domain Architecture	No domain graphic available
Description	Poly(A) RNA polymerase, mitochondrial precursor (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase) (PAP-associated domain-containing protein 1).

CN145_MOUSE
NC score	0.009811 (rank : 21)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	916	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

MYH3_HUMAN
NC score	0.005600 (rank : 22)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	1660	Shared Neighborhood Hits	6
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

RBM19_HUMAN
NC score	0.004990 (rank : 23)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	331	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).