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Network neighborhood for query Sequence : FBXL5_MOUSE

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FBXL5_MOUSE
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBXL5_HUMAN
θ value	0 (rank : 1)	NC score	0.992861 (rank : 2)
Query Neighborhood Hits	103	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

FBXL5_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	103	Target Neighborhood Hits	103	Shared Neighborhood Hits	103
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FXL20_HUMAN
θ value	6.21693e-09 (rank : 3)	NC score	0.456199 (rank : 3)
Query Neighborhood Hits	103	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
θ value	8.11959e-09 (rank : 4)	NC score	0.454691 (rank : 4)
Query Neighborhood Hits	103	Target Neighborhood Hits	78	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FBXL2_MOUSE
θ value	2.36244e-08 (rank : 5)	NC score	0.452882 (rank : 5)
Query Neighborhood Hits	103	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBXL2_HUMAN
θ value	1.53129e-07 (rank : 6)	NC score	0.448515 (rank : 6)
Query Neighborhood Hits	103	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBX4_HUMAN
θ value	1.69304e-06 (rank : 7)	NC score	0.327537 (rank : 19)
Query Neighborhood Hits	103	Target Neighborhood Hits	33	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKT5, Q68CU8, Q86VT8, Q9UK98	Gene names	FBXO4, FBX4
Domain Architecture
Description	F-box only protein 4.

FBX4_MOUSE
θ value	6.43352e-06 (rank : 8)	NC score	0.316802 (rank : 22)
Query Neighborhood Hits	103	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHQ0, Q99JG8	Gene names	Fbxo4, Fbx4
Domain Architecture	No domain graphic available
Description	F-box only protein 4.

FBXL7_HUMAN
θ value	1.43324e-05 (rank : 9)	NC score	0.443137 (rank : 7)
Query Neighborhood Hits	103	Target Neighborhood Hits	91	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FBX11_HUMAN
θ value	2.44474e-05 (rank : 10)	NC score	0.334322 (rank : 17)
Query Neighborhood Hits	103	Target Neighborhood Hits	72	Shared Neighborhood Hits	46
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FBX16_MOUSE
θ value	3.19293e-05 (rank : 11)	NC score	0.349475 (rank : 12)
Query Neighborhood Hits	103	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

FBX16_HUMAN
θ value	4.1701e-05 (rank : 12)	NC score	0.359139 (rank : 10)
Query Neighborhood Hits	103	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FXL13_HUMAN
θ value	0.00035302 (rank : 13)	NC score	0.372193 (rank : 9)
Query Neighborhood Hits	103	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL13_MOUSE
θ value	0.000786445 (rank : 14)	NC score	0.376059 (rank : 8)
Query Neighborhood Hits	103	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FBX15_HUMAN
θ value	0.00102713 (rank : 15)	NC score	0.201653 (rank : 31)
Query Neighborhood Hits	103	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBXW8_HUMAN
θ value	0.00175202 (rank : 16)	NC score	0.248938 (rank : 27)
Query Neighborhood Hits	103	Target Neighborhood Hits	192	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FBX37_MOUSE
θ value	0.00298849 (rank : 17)	NC score	0.344224 (rank : 14)
Query Neighborhood Hits	103	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBXW8_MOUSE
θ value	0.00298849 (rank : 18)	NC score	0.242246 (rank : 29)
Query Neighborhood Hits	103	Target Neighborhood Hits	162	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

FXL14_HUMAN
θ value	0.00509761 (rank : 19)	NC score	0.341096 (rank : 16)
Query Neighborhood Hits	103	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_MOUSE
θ value	0.00509761 (rank : 20)	NC score	0.341711 (rank : 15)
Query Neighborhood Hits	103	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL12_HUMAN
θ value	0.0113563 (rank : 21)	NC score	0.315230 (rank : 23)
Query Neighborhood Hits	103	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FBX8_HUMAN
θ value	0.0148317 (rank : 22)	NC score	0.134493 (rank : 40)
Query Neighborhood Hits	103	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

SKP2_HUMAN
θ value	0.0193708 (rank : 23)	NC score	0.322212 (rank : 20)
Query Neighborhood Hits	103	Target Neighborhood Hits	79	Shared Neighborhood Hits	53
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

TR11B_MOUSE
θ value	0.0193708 (rank : 24)	NC score	0.078468 (rank : 54)
Query Neighborhood Hits	103	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

FBX8_MOUSE
θ value	0.0252991 (rank : 25)	NC score	0.133882 (rank : 42)
Query Neighborhood Hits	103	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FBXL4_HUMAN
θ value	0.0252991 (rank : 26)	NC score	0.345488 (rank : 13)
Query Neighborhood Hits	103	Target Neighborhood Hits	54	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

FXL12_MOUSE
θ value	0.0431538 (rank : 27)	NC score	0.297364 (rank : 25)
Query Neighborhood Hits	103	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

LRC29_HUMAN
θ value	0.0431538 (rank : 28)	NC score	0.357103 (rank : 11)
Query Neighborhood Hits	103	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

FBX37_HUMAN
θ value	0.0563607 (rank : 29)	NC score	0.321769 (rank : 21)
Query Neighborhood Hits	103	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBX27_HUMAN
θ value	0.0736092 (rank : 30)	NC score	0.115301 (rank : 46)
Query Neighborhood Hits	103	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

FXL19_HUMAN
θ value	0.0961366 (rank : 31)	NC score	0.244990 (rank : 28)
Query Neighborhood Hits	103	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
θ value	0.0961366 (rank : 32)	NC score	0.242149 (rank : 30)
Query Neighborhood Hits	103	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

JHD1A_HUMAN
θ value	0.0961366 (rank : 33)	NC score	0.179707 (rank : 35)
Query Neighborhood Hits	103	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

SKP2_MOUSE
θ value	0.0961366 (rank : 34)	NC score	0.298405 (rank : 24)
Query Neighborhood Hits	103	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

JHD1B_HUMAN
θ value	0.125558 (rank : 35)	NC score	0.190043 (rank : 33)
Query Neighborhood Hits	103	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

FXL16_HUMAN
θ value	0.163984 (rank : 36)	NC score	0.332060 (rank : 18)
Query Neighborhood Hits	103	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

GCC2_MOUSE
θ value	0.163984 (rank : 37)	NC score	0.029564 (rank : 82)
Query Neighborhood Hits	103	Target Neighborhood Hits	1619	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

FBX3_HUMAN
θ value	0.21417 (rank : 38)	NC score	0.134028 (rank : 41)
Query Neighborhood Hits	103	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK99, Q9NUX2	Gene names	FBXO3, FBX3
Domain Architecture
Description	F-box only protein 3.

FBXW7_HUMAN
θ value	0.21417 (rank : 39)	NC score	0.083427 (rank : 53)
Query Neighborhood Hits	103	Target Neighborhood Hits	433	Shared Neighborhood Hits	46
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
θ value	0.21417 (rank : 40)	NC score	0.083708 (rank : 52)
Query Neighborhood Hits	103	Target Neighborhood Hits	365	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBX42_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.066548 (rank : 61)
Query Neighborhood Hits	103	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FBX31_HUMAN
θ value	0.365318 (rank : 42)	NC score	0.131083 (rank : 43)
Query Neighborhood Hits	103	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

JHD1A_MOUSE
θ value	0.365318 (rank : 43)	NC score	0.172895 (rank : 37)
Query Neighborhood Hits	103	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

JHD1B_MOUSE
θ value	0.365318 (rank : 44)	NC score	0.182016 (rank : 34)
Query Neighborhood Hits	103	Target Neighborhood Hits	214	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

TACC1_HUMAN
θ value	0.365318 (rank : 45)	NC score	0.058553 (rank : 68)
Query Neighborhood Hits	103	Target Neighborhood Hits	597	Shared Neighborhood Hits	20
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
θ value	0.365318 (rank : 46)	NC score	0.058047 (rank : 69)
Query Neighborhood Hits	103	Target Neighborhood Hits	667	Shared Neighborhood Hits	21
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TPR_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.026300 (rank : 86)
Query Neighborhood Hits	103	Target Neighborhood Hits	1921	Shared Neighborhood Hits	27
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

FBW1B_HUMAN
θ value	0.47712 (rank : 48)	NC score	0.056750 (rank : 72)
Query Neighborhood Hits	103	Target Neighborhood Hits	327	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBW12_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.173913 (rank : 36)
Query Neighborhood Hits	103	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

FBX3_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.114535 (rank : 47)
Query Neighborhood Hits	103	Target Neighborhood Hits	35	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DC63, Q3TKB0	Gene names	Fbxo3, Fba, Fbx3
Domain Architecture
Description	F-box only protein 3.

FBW1A_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.057578 (rank : 70)
Query Neighborhood Hits	103	Target Neighborhood Hits	329	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FXL22_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.252890 (rank : 26)
Query Neighborhood Hits	103	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

PCNT_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.026846 (rank : 85)
Query Neighborhood Hits	103	Target Neighborhood Hits	1551	Shared Neighborhood Hits	26
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

FBX36_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.123743 (rank : 44)
Query Neighborhood Hits	103	Target Neighborhood Hits	30	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NEA4, Q8WWD4	Gene names	FBXO36, FBX36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

FBX36_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.094754 (rank : 48)
Query Neighborhood Hits	103	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CQ24	Gene names	Fbxo36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

SMC2_HUMAN
θ value	1.38821 (rank : 56)	NC score	0.027884 (rank : 84)
Query Neighborhood Hits	103	Target Neighborhood Hits	1405	Shared Neighborhood Hits	25
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SYNE1_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.025360 (rank : 88)
Query Neighborhood Hits	103	Target Neighborhood Hits	1484	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TLR4_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.021972 (rank : 91)
Query Neighborhood Hits	103	Target Neighborhood Hits	279	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QUK6, Q9D691, Q9QZF5, Q9Z203	Gene names	Tlr4, Lps
Domain Architecture
Description	Toll-like receptor 4 precursor (CD284 antigen).

FBX10_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.118332 (rank : 45)
Query Neighborhood Hits	103	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

FBX27_MOUSE
θ value	1.81305 (rank : 60)	NC score	0.076995 (rank : 55)
Query Neighborhood Hits	103	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q6DIA9, Q3TYP0, Q8BKF7	Gene names	Fbxo27
Domain Architecture	No domain graphic available
Description	F-box only protein 27.

MRCKA_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.009014 (rank : 107)
Query Neighborhood Hits	103	Target Neighborhood Hits	1999	Shared Neighborhood Hits	25
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

FBX42_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.054688 (rank : 73)
Query Neighborhood Hits	103	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FXL21_MOUSE
θ value	2.36792 (rank : 63)	NC score	0.138180 (rank : 39)
Query Neighborhood Hits	103	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

RPP29_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.060589 (rank : 67)
Query Neighborhood Hits	103	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O95707, Q5XKL7, Q9UQQ3	Gene names	POP4, RPP29
Domain Architecture
Description	Ribonuclease P protein subunit p29 (EC 3.1.26.5) (hPOP4).

TLR2_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.018632 (rank : 95)
Query Neighborhood Hits	103	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

AN32A_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.064098 (rank : 62)
Query Neighborhood Hits	103	Target Neighborhood Hits	254	Shared Neighborhood Hits	19
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.064098 (rank : 63)
Query Neighborhood Hits	103	Target Neighborhood Hits	254	Shared Neighborhood Hits	19
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

ANR26_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.015021 (rank : 99)
Query Neighborhood Hits	103	Target Neighborhood Hits	1554	Shared Neighborhood Hits	26
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

FBXL6_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.192768 (rank : 32)
Query Neighborhood Hits	103	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FBXW5_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.063089 (rank : 64)
Query Neighborhood Hits	103	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

IFT81_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.034496 (rank : 78)
Query Neighborhood Hits	103	Target Neighborhood Hits	959	Shared Neighborhood Hits	25
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

ITSN2_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.017495 (rank : 97)
Query Neighborhood Hits	103	Target Neighborhood Hits	1173	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ABCA6_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.010258 (rank : 106)
Query Neighborhood Hits	103	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

CCD27_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.033672 (rank : 80)
Query Neighborhood Hits	103	Target Neighborhood Hits	594	Shared Neighborhood Hits	20
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

EEA1_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.020017 (rank : 93)
Query Neighborhood Hits	103	Target Neighborhood Hits	1796	Shared Neighborhood Hits	23
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FBXL3_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.093126 (rank : 49)
Query Neighborhood Hits	103	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKT7, Q9P122	Gene names	FBXL3, FBL3A, FBXL3A
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

KR10A_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.015154 (rank : 98)
Query Neighborhood Hits	103	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

AN32A_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.050721 (rank : 74)
Query Neighborhood Hits	103	Target Neighborhood Hits	234	Shared Neighborhood Hits	18
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

DMD_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.018021 (rank : 96)
Query Neighborhood Hits	103	Target Neighborhood Hits	1111	Shared Neighborhood Hits	22
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

EEA1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.020944 (rank : 92)
Query Neighborhood Hits	103	Target Neighborhood Hits	1637	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FBX44_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.049266 (rank : 76)
Query Neighborhood Hits	103	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BK26, Q8K128	Gene names	Fbxo44, Fbxo6a
Domain Architecture	No domain graphic available
Description	F-box only protein 44 (F-box only protein 6a).

SMC2_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.025773 (rank : 87)
Query Neighborhood Hits	103	Target Neighborhood Hits	1131	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

UN13B_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.011049 (rank : 105)
Query Neighborhood Hits	103	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CSPG2_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.003303 (rank : 111)
Query Neighborhood Hits	103	Target Neighborhood Hits	711	Shared Neighborhood Hits	4
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

FBX39_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.071199 (rank : 59)
Query Neighborhood Hits	103	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

FBXW5_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.061450 (rank : 66)
Query Neighborhood Hits	103	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

GLO2_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.034130 (rank : 79)
Query Neighborhood Hits	103	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q16775	Gene names	HAGH, GLO2, HAGH1
Domain Architecture
Description	Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (GLX II).

HMMR_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.019842 (rank : 94)
Query Neighborhood Hits	103	Target Neighborhood Hits	1082	Shared Neighborhood Hits	23
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

IFT81_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.028073 (rank : 83)
Query Neighborhood Hits	103	Target Neighborhood Hits	893	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

SEP11_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.012753 (rank : 102)
Query Neighborhood Hits	103	Target Neighborhood Hits	300	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

SLK_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.004661 (rank : 110)
Query Neighborhood Hits	103	Target Neighborhood Hits	1775	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ZRF1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.025040 (rank : 89)
Query Neighborhood Hits	103	Target Neighborhood Hits	457	Shared Neighborhood Hits	20
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

AN32D_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.048444 (rank : 77)
Query Neighborhood Hits	103	Target Neighborhood Hits	95	Shared Neighborhood Hits	16
SwissProt Accessions	O95626, Q6NTC4	Gene names	ANP32D, PP32R2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member D (Phosphoprotein 32-related protein 2) (Tumorigenic protein pp32r2).

CENPE_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.014278 (rank : 101)
Query Neighborhood Hits	103	Target Neighborhood Hits	2060	Shared Neighborhood Hits	26
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CRSP3_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.024774 (rank : 90)
Query Neighborhood Hits	103	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULK4, O95403, Q9H0J2, Q9NTT9, Q9NTU0, Q9Y5P7, Q9Y667	Gene names	CRSP3, ARC130, DRIP130, KIAA1216, SUR2
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 3 (Cofactor required for Sp1 transcriptional activation subunit 3) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130) (Activator-recruited cofactor 130 kDa component) (ARC130).

DPP3_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.012706 (rank : 103)
Query Neighborhood Hits	103	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NY33, O95748, Q969H2, Q9BV67, Q9HAL6	Gene names	DPP3
Domain Architecture
Description	Dipeptidyl-peptidase 3 (EC 3.4.14.4) (Dipeptidyl-peptidase III) (DPP III) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III).

E2F4_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.008956 (rank : 108)
Query Neighborhood Hits	103	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

ENAH_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.012198 (rank : 104)
Query Neighborhood Hits	103	Target Neighborhood Hits	919	Shared Neighborhood Hits	18
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FBX33_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.085665 (rank : 51)
Query Neighborhood Hits	103	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

FXL21_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.086922 (rank : 50)
Query Neighborhood Hits	103	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

GLO2_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.030088 (rank : 81)
Query Neighborhood Hits	103	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KB8, Q8WUR9	Gene names	Hagh, Glo2
Domain Architecture
Description	Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II).

KR10B_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.008511 (rank : 109)
Query Neighborhood Hits	103	Target Neighborhood Hits	269	Shared Neighborhood Hits	3
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

MFN1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.014576 (rank : 100)
Query Neighborhood Hits	103	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

FBX15_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.075752 (rank : 56)
Query Neighborhood Hits	103	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QZN0	Gene names	Fbxo15, Fbx15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBX17_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.050027 (rank : 75)
Query Neighborhood Hits	103	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZM8	Gene names	Fbxo17, Fbx17, Fbxo26
Domain Architecture
Description	F-box only protein 17 (F-box only protein 26).

FBX2_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.057207 (rank : 71)
Query Neighborhood Hits	103	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	Q80UW2, Q8R0D2	Gene names	Fbxo2, Fbx2
Domain Architecture	No domain graphic available
Description	F-box only protein 2.

FBX41_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.072506 (rank : 58)
Query Neighborhood Hits	103	Target Neighborhood Hits	475	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.070153 (rank : 60)
Query Neighborhood Hits	103	Target Neighborhood Hits	430	Shared Neighborhood Hits	34
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBXL3_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.062322 (rank : 65)
Query Neighborhood Hits	103	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C4V4, Q80V32, Q8K1W0, Q9QXW1	Gene names	Fbxl3, Fbl3a, Fbxl3a
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

FBXL6_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.157768 (rank : 38)
Query Neighborhood Hits	103	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

FBXL8_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.073278 (rank : 57)
Query Neighborhood Hits	103	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CD0, Q9NUM0	Gene names	FBXL8, FBL8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

Hits sorted by NC score

FBXL5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	103	Target Neighborhood Hits	103	Shared Neighborhood Hits	103
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FBXL5_HUMAN
NC score	0.992861 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	103	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

FXL20_HUMAN
NC score	0.456199 (rank : 3)	θ value	6.21693e-09 (rank : 3)
Query Neighborhood Hits	103	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
NC score	0.454691 (rank : 4)	θ value	8.11959e-09 (rank : 4)
Query Neighborhood Hits	103	Target Neighborhood Hits	78	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FBXL2_MOUSE
NC score	0.452882 (rank : 5)	θ value	2.36244e-08 (rank : 5)
Query Neighborhood Hits	103	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBXL2_HUMAN
NC score	0.448515 (rank : 6)	θ value	1.53129e-07 (rank : 6)
Query Neighborhood Hits	103	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBXL7_HUMAN
NC score	0.443137 (rank : 7)	θ value	1.43324e-05 (rank : 9)
Query Neighborhood Hits	103	Target Neighborhood Hits	91	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FXL13_MOUSE
NC score	0.376059 (rank : 8)	θ value	0.000786445 (rank : 14)
Query Neighborhood Hits	103	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL13_HUMAN
NC score	0.372193 (rank : 9)	θ value	0.00035302 (rank : 13)
Query Neighborhood Hits	103	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FBX16_HUMAN
NC score	0.359139 (rank : 10)	θ value	4.1701e-05 (rank : 12)
Query Neighborhood Hits	103	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

LRC29_HUMAN
NC score	0.357103 (rank : 11)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	103	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

FBX16_MOUSE
NC score	0.349475 (rank : 12)	θ value	3.19293e-05 (rank : 11)
Query Neighborhood Hits	103	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

FBXL4_HUMAN
NC score	0.345488 (rank : 13)	θ value	0.0252991 (rank : 26)
Query Neighborhood Hits	103	Target Neighborhood Hits	54	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

FBX37_MOUSE
NC score	0.344224 (rank : 14)	θ value	0.00298849 (rank : 17)
Query Neighborhood Hits	103	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FXL14_MOUSE
NC score	0.341711 (rank : 15)	θ value	0.00509761 (rank : 20)
Query Neighborhood Hits	103	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_HUMAN
NC score	0.341096 (rank : 16)	θ value	0.00509761 (rank : 19)
Query Neighborhood Hits	103	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FBX11_HUMAN
NC score	0.334322 (rank : 17)	θ value	2.44474e-05 (rank : 10)
Query Neighborhood Hits	103	Target Neighborhood Hits	72	Shared Neighborhood Hits	46
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FXL16_HUMAN
NC score	0.332060 (rank : 18)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	103	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FBX4_HUMAN
NC score	0.327537 (rank : 19)	θ value	1.69304e-06 (rank : 7)
Query Neighborhood Hits	103	Target Neighborhood Hits	33	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKT5, Q68CU8, Q86VT8, Q9UK98	Gene names	FBXO4, FBX4
Domain Architecture
Description	F-box only protein 4.

SKP2_HUMAN
NC score	0.322212 (rank : 20)	θ value	0.0193708 (rank : 23)
Query Neighborhood Hits	103	Target Neighborhood Hits	79	Shared Neighborhood Hits	53
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

FBX37_HUMAN
NC score	0.321769 (rank : 21)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	103	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBX4_MOUSE
NC score	0.316802 (rank : 22)	θ value	6.43352e-06 (rank : 8)
Query Neighborhood Hits	103	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHQ0, Q99JG8	Gene names	Fbxo4, Fbx4
Domain Architecture	No domain graphic available
Description	F-box only protein 4.

FXL12_HUMAN
NC score	0.315230 (rank : 23)	θ value	0.0113563 (rank : 21)
Query Neighborhood Hits	103	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

SKP2_MOUSE
NC score	0.298405 (rank : 24)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	103	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

FXL12_MOUSE
NC score	0.297364 (rank : 25)	θ value	0.0431538 (rank : 27)
Query Neighborhood Hits	103	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL22_MOUSE
NC score	0.252890 (rank : 26)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	103	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

FBXW8_HUMAN
NC score	0.248938 (rank : 27)	θ value	0.00175202 (rank : 16)
Query Neighborhood Hits	103	Target Neighborhood Hits	192	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FXL19_HUMAN
NC score	0.244990 (rank : 28)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	103	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FBXW8_MOUSE
NC score	0.242246 (rank : 29)	θ value	0.00298849 (rank : 18)
Query Neighborhood Hits	103	Target Neighborhood Hits	162	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

FXL19_MOUSE
NC score	0.242149 (rank : 30)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	103	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FBX15_HUMAN
NC score	0.201653 (rank : 31)	θ value	0.00102713 (rank : 15)
Query Neighborhood Hits	103	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBXL6_HUMAN
NC score	0.192768 (rank : 32)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	103	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

JHD1B_HUMAN
NC score	0.190043 (rank : 33)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	103	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
NC score	0.182016 (rank : 34)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	103	Target Neighborhood Hits	214	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

JHD1A_HUMAN
NC score	0.179707 (rank : 35)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	103	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

FBW12_HUMAN
NC score	0.173913 (rank : 36)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	103	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

JHD1A_MOUSE
NC score	0.172895 (rank : 37)	θ value	0.365318 (rank : 43)
Query Neighborhood Hits	103	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

FBXL6_MOUSE
NC score	0.157768 (rank : 38)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	103	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

FXL21_MOUSE
NC score	0.138180 (rank : 39)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	103	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

FBX8_HUMAN
NC score	0.134493 (rank : 40)	θ value	0.0148317 (rank : 22)
Query Neighborhood Hits	103	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FBX3_HUMAN
NC score	0.134028 (rank : 41)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	103	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK99, Q9NUX2	Gene names	FBXO3, FBX3
Domain Architecture
Description	F-box only protein 3.

FBX8_MOUSE
NC score	0.133882 (rank : 42)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	103	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FBX31_HUMAN
NC score	0.131083 (rank : 43)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	103	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

FBX36_HUMAN
NC score	0.123743 (rank : 44)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	103	Target Neighborhood Hits	30	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NEA4, Q8WWD4	Gene names	FBXO36, FBX36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

FBX10_HUMAN
NC score	0.118332 (rank : 45)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	103	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

FBX27_HUMAN
NC score	0.115301 (rank : 46)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	103	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

FBX3_MOUSE
NC score	0.114535 (rank : 47)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	103	Target Neighborhood Hits	35	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DC63, Q3TKB0	Gene names	Fbxo3, Fba, Fbx3
Domain Architecture
Description	F-box only protein 3.

FBX36_MOUSE
NC score	0.094754 (rank : 48)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	103	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CQ24	Gene names	Fbxo36
Domain Architecture	No domain graphic available
Description	F-box only protein 36.

FBXL3_HUMAN
NC score	0.093126 (rank : 49)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	103	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKT7, Q9P122	Gene names	FBXL3, FBL3A, FBXL3A
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

FXL21_HUMAN
NC score	0.086922 (rank : 50)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	103	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

FBX33_HUMAN
NC score	0.085665 (rank : 51)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	103	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

FBXW7_MOUSE
NC score	0.083708 (rank : 52)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	103	Target Neighborhood Hits	365	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBXW7_HUMAN
NC score	0.083427 (rank : 53)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	103	Target Neighborhood Hits	433	Shared Neighborhood Hits	46
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

TR11B_MOUSE
NC score	0.078468 (rank : 54)	θ value	0.0193708 (rank : 24)
Query Neighborhood Hits	103	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

FBX27_MOUSE
NC score	0.076995 (rank : 55)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	103	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q6DIA9, Q3TYP0, Q8BKF7	Gene names	Fbxo27
Domain Architecture	No domain graphic available
Description	F-box only protein 27.

FBX15_MOUSE
NC score	0.075752 (rank : 56)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	103	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QZN0	Gene names	Fbxo15, Fbx15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBXL8_HUMAN
NC score	0.073278 (rank : 57)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	103	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CD0, Q9NUM0	Gene names	FBXL8, FBL8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

FBX41_HUMAN
NC score	0.072506 (rank : 58)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	103	Target Neighborhood Hits	475	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX39_MOUSE
NC score	0.071199 (rank : 59)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	103	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

FBX41_MOUSE
NC score	0.070153 (rank : 60)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	103	Target Neighborhood Hits	430	Shared Neighborhood Hits	34
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX42_HUMAN
NC score	0.066548 (rank : 61)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	103	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

AN32A_MOUSE
NC score	0.064098 (rank : 62)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	103	Target Neighborhood Hits	254	Shared Neighborhood Hits	19
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
NC score	0.064098 (rank : 63)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	103	Target Neighborhood Hits	254	Shared Neighborhood Hits	19
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

FBXW5_MOUSE
NC score	0.063089 (rank : 64)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	103	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBXL3_MOUSE
NC score	0.062322 (rank : 65)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	103	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C4V4, Q80V32, Q8K1W0, Q9QXW1	Gene names	Fbxl3, Fbl3a, Fbxl3a
Domain Architecture
Description	F-box/LRR-repeat protein 3 (F-box/LRR-repeat protein 3A) (F-box and leucine-rich repeat protein 3A).

FBXW5_HUMAN
NC score	0.061450 (rank : 66)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	103	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

RPP29_HUMAN
NC score	0.060589 (rank : 67)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	103	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O95707, Q5XKL7, Q9UQQ3	Gene names	POP4, RPP29
Domain Architecture
Description	Ribonuclease P protein subunit p29 (EC 3.1.26.5) (hPOP4).

TACC1_HUMAN
NC score	0.058553 (rank : 68)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	103	Target Neighborhood Hits	597	Shared Neighborhood Hits	20
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
NC score	0.058047 (rank : 69)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	103	Target Neighborhood Hits	667	Shared Neighborhood Hits	21
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

FBW1A_HUMAN
NC score	0.057578 (rank : 70)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	103	Target Neighborhood Hits	329	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FBX2_MOUSE
NC score	0.057207 (rank : 71)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	103	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	Q80UW2, Q8R0D2	Gene names	Fbxo2, Fbx2
Domain Architecture	No domain graphic available
Description	F-box only protein 2.

FBW1B_HUMAN
NC score	0.056750 (rank : 72)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	103	Target Neighborhood Hits	327	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBX42_MOUSE
NC score	0.054688 (rank : 73)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	103	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

AN32A_HUMAN
NC score	0.050721 (rank : 74)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	103	Target Neighborhood Hits	234	Shared Neighborhood Hits	18
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

FBX17_MOUSE
NC score	0.050027 (rank : 75)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	103	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZM8	Gene names	Fbxo17, Fbx17, Fbxo26
Domain Architecture
Description	F-box only protein 17 (F-box only protein 26).

FBX44_MOUSE
NC score	0.049266 (rank : 76)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	103	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BK26, Q8K128	Gene names	Fbxo44, Fbxo6a
Domain Architecture	No domain graphic available
Description	F-box only protein 44 (F-box only protein 6a).

AN32D_HUMAN
NC score	0.048444 (rank : 77)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	103	Target Neighborhood Hits	95	Shared Neighborhood Hits	16
SwissProt Accessions	O95626, Q6NTC4	Gene names	ANP32D, PP32R2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member D (Phosphoprotein 32-related protein 2) (Tumorigenic protein pp32r2).

IFT81_MOUSE
NC score	0.034496 (rank : 78)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	103	Target Neighborhood Hits	959	Shared Neighborhood Hits	25
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

GLO2_HUMAN
NC score	0.034130 (rank : 79)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	103	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q16775	Gene names	HAGH, GLO2, HAGH1
Domain Architecture
Description	Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (GLX II).

CCD27_HUMAN
NC score	0.033672 (rank : 80)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	103	Target Neighborhood Hits	594	Shared Neighborhood Hits	20
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

GLO2_MOUSE
NC score	0.030088 (rank : 81)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	103	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KB8, Q8WUR9	Gene names	Hagh, Glo2
Domain Architecture
Description	Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II).

GCC2_MOUSE
NC score	0.029564 (rank : 82)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	103	Target Neighborhood Hits	1619	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

IFT81_HUMAN
NC score	0.028073 (rank : 83)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	103	Target Neighborhood Hits	893	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

SMC2_HUMAN
NC score	0.027884 (rank : 84)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	103	Target Neighborhood Hits	1405	Shared Neighborhood Hits	25
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

PCNT_HUMAN
NC score	0.026846 (rank : 85)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	103	Target Neighborhood Hits	1551	Shared Neighborhood Hits	26
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

TPR_HUMAN
NC score	0.026300 (rank : 86)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	103	Target Neighborhood Hits	1921	Shared Neighborhood Hits	27
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SMC2_MOUSE
NC score	0.025773 (rank : 87)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	103	Target Neighborhood Hits	1131	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SYNE1_HUMAN
NC score	0.025360 (rank : 88)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	103	Target Neighborhood Hits	1484	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ZRF1_HUMAN
NC score	0.025040 (rank : 89)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	103	Target Neighborhood Hits	457	Shared Neighborhood Hits	20
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

CRSP3_HUMAN
NC score	0.024774 (rank : 90)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	103	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULK4, O95403, Q9H0J2, Q9NTT9, Q9NTU0, Q9Y5P7, Q9Y667	Gene names	CRSP3, ARC130, DRIP130, KIAA1216, SUR2
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 3 (Cofactor required for Sp1 transcriptional activation subunit 3) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130) (Activator-recruited cofactor 130 kDa component) (ARC130).

TLR4_MOUSE
NC score	0.021972 (rank : 91)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	103	Target Neighborhood Hits	279	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QUK6, Q9D691, Q9QZF5, Q9Z203	Gene names	Tlr4, Lps
Domain Architecture
Description	Toll-like receptor 4 precursor (CD284 antigen).

EEA1_MOUSE
NC score	0.020944 (rank : 92)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	103	Target Neighborhood Hits	1637	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EEA1_HUMAN
NC score	0.020017 (rank : 93)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	103	Target Neighborhood Hits	1796	Shared Neighborhood Hits	23
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

HMMR_HUMAN
NC score	0.019842 (rank : 94)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	103	Target Neighborhood Hits	1082	Shared Neighborhood Hits	23
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

TLR2_HUMAN
NC score	0.018632 (rank : 95)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	103	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

DMD_MOUSE
NC score	0.018021 (rank : 96)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	103	Target Neighborhood Hits	1111	Shared Neighborhood Hits	22
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

ITSN2_HUMAN
NC score	0.017495 (rank : 97)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	103	Target Neighborhood Hits	1173	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

KR10A_HUMAN
NC score	0.015154 (rank : 98)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	103	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

ANR26_MOUSE
NC score	0.015021 (rank : 99)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	103	Target Neighborhood Hits	1554	Shared Neighborhood Hits	26
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MFN1_HUMAN
NC score	0.014576 (rank : 100)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	103	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

CENPE_HUMAN
NC score	0.014278 (rank : 101)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	103	Target Neighborhood Hits	2060	Shared Neighborhood Hits	26
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

SEP11_MOUSE
NC score	0.012753 (rank : 102)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	103	Target Neighborhood Hits	300	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

DPP3_HUMAN
NC score	0.012706 (rank : 103)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	103	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NY33, O95748, Q969H2, Q9BV67, Q9HAL6	Gene names	DPP3
Domain Architecture
Description	Dipeptidyl-peptidase 3 (EC 3.4.14.4) (Dipeptidyl-peptidase III) (DPP III) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III).

ENAH_MOUSE
NC score	0.012198 (rank : 104)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	103	Target Neighborhood Hits	919	Shared Neighborhood Hits	18
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

UN13B_HUMAN
NC score	0.011049 (rank : 105)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	103	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ABCA6_HUMAN
NC score	0.010258 (rank : 106)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	103	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

MRCKA_HUMAN
NC score	0.009014 (rank : 107)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	103	Target Neighborhood Hits	1999	Shared Neighborhood Hits	25
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

E2F4_HUMAN
NC score	0.008956 (rank : 108)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	103	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

KR10B_HUMAN
NC score	0.008511 (rank : 109)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	103	Target Neighborhood Hits	269	Shared Neighborhood Hits	3
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

SLK_HUMAN
NC score	0.004661 (rank : 110)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	103	Target Neighborhood Hits	1775	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

CSPG2_MOUSE
NC score	0.003303 (rank : 111)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	103	Target Neighborhood Hits	711	Shared Neighborhood Hits	4
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).