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Network neighborhood for query Sequence : FBX10_HUMAN

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FBX10_HUMAN
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBX10_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

FBX11_HUMAN
θ value	5.57106e-42 (rank : 2)	NC score	0.669770 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	72	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FBSP1_MOUSE
θ value	0.00298849 (rank : 3)	NC score	0.120630 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

SHCBP_MOUSE
θ value	0.00869519 (rank : 4)	NC score	0.133678 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z179, Q3UED9, Q3UMD9	Gene names	Shcbp1, Pal
Domain Architecture	No domain graphic available
Description	SHC SH2 domain-binding protein 1 (Protein expressed in activated lymphocytes) (mPAL) (SHC-binding protein).

SKP2_MOUSE
θ value	0.0736092 (rank : 5)	NC score	0.160837 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

FXL20_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.136852 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	77	Shared Neighborhood Hits	22
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
θ value	0.21417 (rank : 7)	NC score	0.137087 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FBXL2_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.132794 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBXW8_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.111282 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	192	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FBXL2_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.130007 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

PAR6G_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.029043 (rank : 43)
Query Neighborhood Hits	35	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

FBXL5_MOUSE
θ value	1.81305 (rank : 12)	NC score	0.118332 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	103	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FBXW8_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.098488 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

SKP2_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.138802 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	79	Shared Neighborhood Hits	20
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

JHD1A_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.051158 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

SHCBP_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.082102 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEM2, Q96N60, Q9BVS0, Q9H6P6	Gene names	SHCBP1
Domain Architecture	No domain graphic available
Description	SHC SH2 domain-binding protein 1.

TM119_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.039054 (rank : 40)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q4V9L6, Q6UXE5, Q8N2F5	Gene names	TMEM119
Domain Architecture	No domain graphic available
Description	Transmembrane protein 119 precursor.

FBX18_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.050288 (rank : 37)
Query Neighborhood Hits	35	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFZ0, Q7Z4Q6, Q7Z4R0, Q8N1P5, Q8N586, Q96E82, Q96K67, Q96SW7, Q9UFB2	Gene names	FBXO18, FBH1, FBX18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

FBX18_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.053884 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2I9, Q8C444, Q99KS0, Q9CTC6, Q9QZG7	Gene names	Fbxo18, Fbh1, Fbx18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

FBXL5_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.107513 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	111	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

FBXL7_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.123361 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

JHD1A_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.050581 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

NCOA3_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.014885 (rank : 48)
Query Neighborhood Hits	35	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

FBX39_MOUSE
θ value	6.88961 (rank : 24)	NC score	0.050080 (rank : 38)
Query Neighborhood Hits	35	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

FBXL8_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.055296 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	Q96CD0, Q9NUM0	Gene names	FBXL8, FBL8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

FBXW4_HUMAN
θ value	6.88961 (rank : 26)	NC score	0.037590 (rank : 42)
Query Neighborhood Hits	35	Target Neighborhood Hits	209	Shared Neighborhood Hits	14
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

FBX27_HUMAN
θ value	8.99809 (rank : 27)	NC score	0.019109 (rank : 47)
Query Neighborhood Hits	35	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

FBX47_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.026664 (rank : 44)
Query Neighborhood Hits	35	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q5MNV8	Gene names	FBXO47
Domain Architecture	No domain graphic available
Description	F-box only protein 47.

FBXL8_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.038270 (rank : 41)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CIG9, Q9QZN7	Gene names	Fbxl8, Fbl8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

FXL14_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.076944 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.077090 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL21_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.063833 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

IRS1_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.020080 (rank : 45)
Query Neighborhood Hits	35	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.019856 (rank : 46)
Query Neighborhood Hits	35	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

OGFR_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.004843 (rank : 49)
Query Neighborhood Hits	35	Target Neighborhood Hits	1582	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

FBX15_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.056998 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBX16_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.050750 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FBX37_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.055423 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBX37_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.054970 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBXL4_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.087774 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

FBXL6_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.067772 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FXL12_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.083760 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL12_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.078911 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	79	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL13_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.063735 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	81	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL13_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.062352 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	70	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL16_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.066873 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FXL19_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.050013 (rank : 39)
Query Neighborhood Hits	35	Target Neighborhood Hits	147	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL22_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.051682 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

LRC29_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.060998 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

Hits sorted by NC score

FBX10_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

FBX11_HUMAN
NC score	0.669770 (rank : 2)	θ value	5.57106e-42 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	72	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

SKP2_MOUSE
NC score	0.160837 (rank : 3)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

SKP2_HUMAN
NC score	0.138802 (rank : 4)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	79	Shared Neighborhood Hits	20
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

FXL20_MOUSE
NC score	0.137087 (rank : 5)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_HUMAN
NC score	0.136852 (rank : 6)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	77	Shared Neighborhood Hits	22
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

SHCBP_MOUSE
NC score	0.133678 (rank : 7)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z179, Q3UED9, Q3UMD9	Gene names	Shcbp1, Pal
Domain Architecture	No domain graphic available
Description	SHC SH2 domain-binding protein 1 (Protein expressed in activated lymphocytes) (mPAL) (SHC-binding protein).

FBXL2_HUMAN
NC score	0.132794 (rank : 8)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBXL2_MOUSE
NC score	0.130007 (rank : 9)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBXL7_HUMAN
NC score	0.123361 (rank : 10)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FBSP1_MOUSE
NC score	0.120630 (rank : 11)	θ value	0.00298849 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

FBXL5_MOUSE
NC score	0.118332 (rank : 12)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	103	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FBXW8_HUMAN
NC score	0.111282 (rank : 13)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	192	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FBXL5_HUMAN
NC score	0.107513 (rank : 14)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	111	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

FBXW8_MOUSE
NC score	0.098488 (rank : 15)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

FBXL4_HUMAN
NC score	0.087774 (rank : 16)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	35	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKA2, O95919, Q9UJU0	Gene names	FBXL4, FBL4, FBL5
Domain Architecture
Description	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5).

FXL12_HUMAN
NC score	0.083760 (rank : 17)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	35	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

SHCBP_HUMAN
NC score	0.082102 (rank : 18)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEM2, Q96N60, Q9BVS0, Q9H6P6	Gene names	SHCBP1
Domain Architecture	No domain graphic available
Description	SHC SH2 domain-binding protein 1.

FXL12_MOUSE
NC score	0.078911 (rank : 19)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	35	Target Neighborhood Hits	79	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL14_MOUSE
NC score	0.077090 (rank : 20)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_HUMAN
NC score	0.076944 (rank : 21)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FBXL6_HUMAN
NC score	0.067772 (rank : 22)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	35	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

FXL16_HUMAN
NC score	0.066873 (rank : 23)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	35	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FXL21_MOUSE
NC score	0.063833 (rank : 24)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

FXL13_HUMAN
NC score	0.063735 (rank : 25)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	35	Target Neighborhood Hits	81	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL13_MOUSE
NC score	0.062352 (rank : 26)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	35	Target Neighborhood Hits	70	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

LRC29_HUMAN
NC score	0.060998 (rank : 27)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

FBX15_HUMAN
NC score	0.056998 (rank : 28)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NCQ5	Gene names	FBXO15, FBX15
Domain Architecture	No domain graphic available
Description	F-box only protein 15.

FBX37_HUMAN
NC score	0.055423 (rank : 29)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBXL8_HUMAN
NC score	0.055296 (rank : 30)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	Q96CD0, Q9NUM0	Gene names	FBXL8, FBL8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

FBX37_MOUSE
NC score	0.054970 (rank : 31)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBX18_MOUSE
NC score	0.053884 (rank : 32)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2I9, Q8C444, Q99KS0, Q9CTC6, Q9QZG7	Gene names	Fbxo18, Fbh1, Fbx18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

FXL22_MOUSE
NC score	0.051682 (rank : 33)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	35	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C7B6, Q8C3G3, Q8C3V6	Gene names	Fbxl22
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 22 (F-box and leucine-rich repeat protein 22).

JHD1A_MOUSE
NC score	0.051158 (rank : 34)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

FBX16_HUMAN
NC score	0.050750 (rank : 35)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	35	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

JHD1A_HUMAN
NC score	0.050581 (rank : 36)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

FBX18_HUMAN
NC score	0.050288 (rank : 37)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFZ0, Q7Z4Q6, Q7Z4R0, Q8N1P5, Q8N586, Q96E82, Q96K67, Q96SW7, Q9UFB2	Gene names	FBXO18, FBH1, FBX18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

FBX39_MOUSE
NC score	0.050080 (rank : 38)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q5NBU5	Gene names	Fbxo39
Domain Architecture	No domain graphic available
Description	F-box only protein 39.

FXL19_HUMAN
NC score	0.050013 (rank : 39)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	35	Target Neighborhood Hits	147	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

TM119_HUMAN
NC score	0.039054 (rank : 40)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q4V9L6, Q6UXE5, Q8N2F5	Gene names	TMEM119
Domain Architecture	No domain graphic available
Description	Transmembrane protein 119 precursor.

FBXL8_MOUSE
NC score	0.038270 (rank : 41)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CIG9, Q9QZN7	Gene names	Fbxl8, Fbl8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

FBXW4_HUMAN
NC score	0.037590 (rank : 42)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	209	Shared Neighborhood Hits	14
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

PAR6G_HUMAN
NC score	0.029043 (rank : 43)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

FBX47_HUMAN
NC score	0.026664 (rank : 44)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q5MNV8	Gene names	FBXO47
Domain Architecture	No domain graphic available
Description	F-box only protein 47.

IRS1_HUMAN
NC score	0.020080 (rank : 45)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
NC score	0.019856 (rank : 46)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

FBX27_HUMAN
NC score	0.019109 (rank : 47)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

NCOA3_HUMAN
NC score	0.014885 (rank : 48)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

OGFR_HUMAN
NC score	0.004843 (rank : 49)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	1582	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).