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Network neighborhood for query Sequence : IRS1_MOUSE

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IRS1_MOUSE
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRS1_HUMAN
θ value	0 (rank : 1)	NC score	0.981650 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	62
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS2_HUMAN
θ value	3.06949e-141 (rank : 3)	NC score	0.852019 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	262	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

IRS2_MOUSE
θ value	2.97304e-136 (rank : 4)	NC score	0.851110 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	248	Shared Neighborhood Hits	26
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

DOK5_MOUSE
θ value	1.80886e-08 (rank : 5)	NC score	0.309853 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

DOK5_HUMAN
θ value	8.97725e-08 (rank : 6)	NC score	0.301940 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

DOK6_HUMAN
θ value	1.17247e-07 (rank : 7)	NC score	0.311678 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

DOK4_HUMAN
θ value	2.21117e-06 (rank : 8)	NC score	0.279597 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

GAB2_MOUSE
θ value	2.21117e-06 (rank : 9)	NC score	0.244278 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	220	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

DOK4_MOUSE
θ value	4.92598e-06 (rank : 10)	NC score	0.275611 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

GAB2_HUMAN
θ value	1.87187e-05 (rank : 11)	NC score	0.237965 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB1_HUMAN
θ value	4.1701e-05 (rank : 12)	NC score	0.264127 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	9.29e-05 (rank : 13)	NC score	0.209796 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	233	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MUC1_HUMAN
θ value	0.00102713 (rank : 14)	NC score	0.061024 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	975	Shared Neighborhood Hits	38
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

DOCK9_MOUSE
θ value	0.00298849 (rank : 15)	NC score	0.093657 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	79	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_HUMAN
θ value	0.00390308 (rank : 16)	NC score	0.090815 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

GON4L_HUMAN
θ value	0.0193708 (rank : 17)	NC score	0.061117 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	555	Shared Neighborhood Hits	22
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

RNPS1_HUMAN
θ value	0.0193708 (rank : 18)	NC score	0.088745 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	0.0193708 (rank : 19)	NC score	0.088745 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

ULK2_HUMAN
θ value	0.0193708 (rank : 20)	NC score	0.017507 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	979	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

K0323_HUMAN
θ value	0.0252991 (rank : 21)	NC score	0.071637 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

CIC_HUMAN
θ value	0.0431538 (rank : 22)	NC score	0.064069 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	992	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TGON1_MOUSE
θ value	0.0961366 (rank : 23)	NC score	0.060176 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

MAST2_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.013370 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	1189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	0.125558 (rank : 25)	NC score	0.013929 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	1110	Shared Neighborhood Hits	17
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

ZBT45_HUMAN
θ value	0.125558 (rank : 26)	NC score	0.007308 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	901	Shared Neighborhood Hits	19
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

TCF19_MOUSE
θ value	0.163984 (rank : 27)	NC score	0.066119 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

DOK2_MOUSE
θ value	0.21417 (rank : 28)	NC score	0.120451 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	244	Shared Neighborhood Hits	22
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

MAGE1_HUMAN
θ value	0.21417 (rank : 29)	NC score	0.048900 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	1389	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TISB_HUMAN
θ value	0.279714 (rank : 30)	NC score	0.048324 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

TISB_MOUSE
θ value	0.47712 (rank : 31)	NC score	0.046216 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

TS13_MOUSE
θ value	0.47712 (rank : 32)	NC score	0.050434 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

IASPP_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.037541 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	1024	Shared Neighborhood Hits	37
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LRC56_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.036106 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

SOS2_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.033572 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

TCGAP_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.039407 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	872	Shared Neighborhood Hits	30
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TGON2_MOUSE
θ value	0.62314 (rank : 37)	NC score	0.052672 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	277	Shared Neighborhood Hits	15
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

PARPT_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.024814 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

SC24C_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.048221 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	662	Shared Neighborhood Hits	39
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SYNP2_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.040162 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	323	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

FA47A_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.044558 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	451	Shared Neighborhood Hits	23
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

GLI1_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.008702 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	828	Shared Neighborhood Hits	17
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

PI5PA_MOUSE
θ value	1.06291 (rank : 43)	NC score	0.032675 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SPEG_MOUSE
θ value	1.06291 (rank : 44)	NC score	0.017557 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	1959	Shared Neighborhood Hits	48
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRRM2_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.078583 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	1296	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CDSN_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.041676 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q15517, O43509, Q5SQ85, Q5STD2, Q7LA70, Q7LA71, Q86Z04, Q8IZU4, Q8IZU5, Q8IZU6, Q8N5P3, Q95IF9, Q9NP52, Q9NPE0, Q9NPG5, Q9NRH4, Q9NRH5, Q9NRH6, Q9NRH7, Q9NRH8, Q9UBH8, Q9UIN6, Q9UIN7, Q9UIN8, Q9UIN9, Q9UIP0	Gene names	CDSN
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor (S protein).

DPOLZ_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.021238 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

ITF2_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.035845 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

K0310_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.066416 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	420	Shared Neighborhood Hits	31
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MAP1B_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.053179 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	903	Shared Neighborhood Hits	24
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.036249 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	977	Shared Neighborhood Hits	20
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NFAC3_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.025985 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

PRRT3_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.053133 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	998	Shared Neighborhood Hits	35
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RNF25_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.028879 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

ARBK1_MOUSE
θ value	1.81305 (rank : 55)	NC score	0.011276 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	849	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

CB013_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.040089 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IW19, Q53P47, Q53PB9, Q53QU0	Gene names	C2orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13.

FBX42_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.022608 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

ITF2_MOUSE
θ value	1.81305 (rank : 58)	NC score	0.033538 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

MAP1A_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.038044 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	1626	Shared Neighborhood Hits	41
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SRRM2_MOUSE
θ value	1.81305 (rank : 60)	NC score	0.078310 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	1470	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SSBP3_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.029553 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.029553 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

ARBK1_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.010782 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	859	Shared Neighborhood Hits	11
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

FHOD1_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.036236 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GPTC8_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.039665 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	366	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

MUC5B_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.024129 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	1020	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYO10_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.017979 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	920	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

SYCP1_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.009010 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	1313	Shared Neighborhood Hits	11
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CM007_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.020161 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

FKRP_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.022189 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG64, Q8BJR3	Gene names	Fkrp
Domain Architecture
Description	Fukutin-related protein (EC 2.-.-.-).

GRIN1_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.035722 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	681	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

LRRF2_MOUSE
θ value	3.0926 (rank : 72)	NC score	0.017623 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	556	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

PPRB_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.046717 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	354	Shared Neighborhood Hits	28
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SDK1_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.005164 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	511	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

ULK2_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.010917 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	943	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

APC_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.025646 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	603	Shared Neighborhood Hits	21
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

LRRF2_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.013690 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	791	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

PLEK2_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.040102 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.038354 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

T22D2_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.056790 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

CBP_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.029237 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	941	Shared Neighborhood Hits	39
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.029529 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	1051	Shared Neighborhood Hits	47
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CS007_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.024424 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	401	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CSKI1_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.011681 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	1031	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CTND2_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.011476 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

PKHA6_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.047857 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	591	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PPRB_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.036812 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	311	Shared Neighborhood Hits	21
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

WIRE_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.042183 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	310	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

AUTS2_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.019442 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAT4_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.013871 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BTBDC_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.036115 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	248	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CEP68_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.015722 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CIC_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.047478 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	742	Shared Neighborhood Hits	32
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DLGP2_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.008848 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

FRS2_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.060853 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WU20, O43558, Q7LDQ6	Gene names	FRS2
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT).

HXD8_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.006272 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	333	Shared Neighborhood Hits	4
SwissProt Accessions	P23463	Gene names	Hoxd8, Hox-4.3, Hoxd-8
Domain Architecture
Description	Homeobox protein Hox-D8 (Hox-4.3) (Hox-5.4).

NOTC2_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.001681 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	1069	Shared Neighborhood Hits	14
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PKHA6_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.035319 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	556	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PMS2_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.024416 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

SPRE3_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.021509 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

WDR33_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.007448 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	638	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

CO002_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.040110 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	387	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CT075_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.006726 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

FBX10_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.019856 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

FRS3_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.057732 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

LRC4B_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.002302 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	479	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

PKHA1_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.047663 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

RAI1_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.017977 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	360	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

T2R41_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.005916 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	P59536, P59550	Gene names	TAS2R41
Domain Architecture
Description	Taste receptor type 2 member 41 (T2R41) (T2R59).

TM16H_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.012540 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TRIO_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.008437 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	1580	Shared Neighborhood Hits	26
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

ZBT37_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.000244 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	815	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

DOC10_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.064455 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOK1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.077087 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

DOK1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.065919 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

DOK2_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.094267 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

DOK3_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.054844 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

DOK3_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.068254 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

FRS3_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.053480 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

Hits sorted by NC score

IRS1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_HUMAN
NC score	0.981650 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	62
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS2_HUMAN
NC score	0.852019 (rank : 3)	θ value	3.06949e-141 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	262	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

IRS2_MOUSE
NC score	0.851110 (rank : 4)	θ value	2.97304e-136 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	248	Shared Neighborhood Hits	26
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

DOK6_HUMAN
NC score	0.311678 (rank : 5)	θ value	1.17247e-07 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

DOK5_MOUSE
NC score	0.309853 (rank : 6)	θ value	1.80886e-08 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

DOK5_HUMAN
NC score	0.301940 (rank : 7)	θ value	8.97725e-08 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

DOK4_HUMAN
NC score	0.279597 (rank : 8)	θ value	2.21117e-06 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_MOUSE
NC score	0.275611 (rank : 9)	θ value	4.92598e-06 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

GAB1_HUMAN
NC score	0.264127 (rank : 10)	θ value	4.1701e-05 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB2_MOUSE
NC score	0.244278 (rank : 11)	θ value	2.21117e-06 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	220	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GAB2_HUMAN
NC score	0.237965 (rank : 12)	θ value	1.87187e-05 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB1_MOUSE
NC score	0.209796 (rank : 13)	θ value	9.29e-05 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	233	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

DOK2_MOUSE
NC score	0.120451 (rank : 14)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	244	Shared Neighborhood Hits	22
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DOK2_HUMAN
NC score	0.094267 (rank : 15)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

DOCK9_MOUSE
NC score	0.093657 (rank : 16)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	79	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_HUMAN
NC score	0.090815 (rank : 17)	θ value	0.00390308 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

RNPS1_HUMAN
NC score	0.088745 (rank : 18)	θ value	0.0193708 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.088745 (rank : 19)	θ value	0.0193708 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

SRRM2_HUMAN
NC score	0.078583 (rank : 20)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	1296	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.078310 (rank : 21)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	1470	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

DOK1_HUMAN
NC score	0.077087 (rank : 22)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

K0323_HUMAN
NC score	0.071637 (rank : 23)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

DOK3_MOUSE
NC score	0.068254 (rank : 24)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

K0310_HUMAN
NC score	0.066416 (rank : 25)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	420	Shared Neighborhood Hits	31
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

TCF19_MOUSE
NC score	0.066119 (rank : 26)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

DOK1_MOUSE
NC score	0.065919 (rank : 27)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

DOC10_HUMAN
NC score	0.064455 (rank : 28)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

CIC_HUMAN
NC score	0.064069 (rank : 29)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	992	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

GON4L_HUMAN
NC score	0.061117 (rank : 30)	θ value	0.0193708 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	555	Shared Neighborhood Hits	22
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MUC1_HUMAN
NC score	0.061024 (rank : 31)	θ value	0.00102713 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	975	Shared Neighborhood Hits	38
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

FRS2_HUMAN
NC score	0.060853 (rank : 32)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WU20, O43558, Q7LDQ6	Gene names	FRS2
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT).

TGON1_MOUSE
NC score	0.060176 (rank : 33)	θ value	0.0961366 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

FRS3_MOUSE
NC score	0.057732 (rank : 34)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

T22D2_HUMAN
NC score	0.056790 (rank : 35)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

DOK3_HUMAN
NC score	0.054844 (rank : 36)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

FRS3_HUMAN
NC score	0.053480 (rank : 37)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

MAP1B_HUMAN
NC score	0.053179 (rank : 38)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	903	Shared Neighborhood Hits	24
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

PRRT3_HUMAN
NC score	0.053133 (rank : 39)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	998	Shared Neighborhood Hits	35
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TGON2_MOUSE
NC score	0.052672 (rank : 40)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	277	Shared Neighborhood Hits	15
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TS13_MOUSE
NC score	0.050434 (rank : 41)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

MAGE1_HUMAN
NC score	0.048900 (rank : 42)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	1389	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TISB_HUMAN
NC score	0.048324 (rank : 43)	θ value	0.279714 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

SC24C_HUMAN
NC score	0.048221 (rank : 44)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	662	Shared Neighborhood Hits	39
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

PKHA6_MOUSE
NC score	0.047857 (rank : 45)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	591	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA1_MOUSE
NC score	0.047663 (rank : 46)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

CIC_MOUSE
NC score	0.047478 (rank : 47)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	742	Shared Neighborhood Hits	32
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

PPRB_MOUSE
NC score	0.046717 (rank : 48)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	354	Shared Neighborhood Hits	28
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

TISB_MOUSE
NC score	0.046216 (rank : 49)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

FA47A_HUMAN
NC score	0.044558 (rank : 50)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	451	Shared Neighborhood Hits	23
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

WIRE_MOUSE
NC score	0.042183 (rank : 51)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	310	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CDSN_HUMAN
NC score	0.041676 (rank : 52)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q15517, O43509, Q5SQ85, Q5STD2, Q7LA70, Q7LA71, Q86Z04, Q8IZU4, Q8IZU5, Q8IZU6, Q8N5P3, Q95IF9, Q9NP52, Q9NPE0, Q9NPG5, Q9NRH4, Q9NRH5, Q9NRH6, Q9NRH7, Q9NRH8, Q9UBH8, Q9UIN6, Q9UIN7, Q9UIN8, Q9UIN9, Q9UIP0	Gene names	CDSN
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor (S protein).

SYNP2_HUMAN
NC score	0.040162 (rank : 53)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	323	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

CO002_HUMAN
NC score	0.040110 (rank : 54)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	387	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

PLEK2_HUMAN
NC score	0.040102 (rank : 55)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

CB013_HUMAN
NC score	0.040089 (rank : 56)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IW19, Q53P47, Q53PB9, Q53QU0	Gene names	C2orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13.

GPTC8_HUMAN
NC score	0.039665 (rank : 57)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	366	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

TCGAP_HUMAN
NC score	0.039407 (rank : 58)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	872	Shared Neighborhood Hits	30
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

PLEK2_MOUSE
NC score	0.038354 (rank : 59)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

MAP1A_HUMAN
NC score	0.038044 (rank : 60)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	1626	Shared Neighborhood Hits	41
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

IASPP_MOUSE
NC score	0.037541 (rank : 61)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	1024	Shared Neighborhood Hits	37
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PPRB_HUMAN
NC score	0.036812 (rank : 62)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	311	Shared Neighborhood Hits	21
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

MAP1B_MOUSE
NC score	0.036249 (rank : 63)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	977	Shared Neighborhood Hits	20
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

FHOD1_MOUSE
NC score	0.036236 (rank : 64)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

BTBDC_HUMAN
NC score	0.036115 (rank : 65)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	248	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

LRC56_HUMAN
NC score	0.036106 (rank : 66)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

ITF2_HUMAN
NC score	0.035845 (rank : 67)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

GRIN1_HUMAN
NC score	0.035722 (rank : 68)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	681	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PKHA6_HUMAN
NC score	0.035319 (rank : 69)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	556	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SOS2_HUMAN
NC score	0.033572 (rank : 70)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

ITF2_MOUSE
NC score	0.033538 (rank : 71)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

PI5PA_MOUSE
NC score	0.032675 (rank : 72)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SSBP3_HUMAN
NC score	0.029553 (rank : 73)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
NC score	0.029553 (rank : 74)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

CBP_MOUSE
NC score	0.029529 (rank : 75)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	1051	Shared Neighborhood Hits	47
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_HUMAN
NC score	0.029237 (rank : 76)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	941	Shared Neighborhood Hits	39
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RNF25_HUMAN
NC score	0.028879 (rank : 77)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

NFAC3_HUMAN
NC score	0.025985 (rank : 78)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

APC_HUMAN
NC score	0.025646 (rank : 79)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	603	Shared Neighborhood Hits	21
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PARPT_MOUSE
NC score	0.024814 (rank : 80)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

CS007_HUMAN
NC score	0.024424 (rank : 81)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	401	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

PMS2_HUMAN
NC score	0.024416 (rank : 82)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

MUC5B_HUMAN
NC score	0.024129 (rank : 83)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	1020	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

FBX42_HUMAN
NC score	0.022608 (rank : 84)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FKRP_MOUSE
NC score	0.022189 (rank : 85)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG64, Q8BJR3	Gene names	Fkrp
Domain Architecture
Description	Fukutin-related protein (EC 2.-.-.-).

SPRE3_MOUSE
NC score	0.021509 (rank : 86)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

DPOLZ_MOUSE
NC score	0.021238 (rank : 87)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

CM007_MOUSE
NC score	0.020161 (rank : 88)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

FBX10_HUMAN
NC score	0.019856 (rank : 89)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

AUTS2_HUMAN
NC score	0.019442 (rank : 90)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

MYO10_HUMAN
NC score	0.017979 (rank : 91)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	920	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

RAI1_HUMAN
NC score	0.017977 (rank : 92)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	360	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

LRRF2_MOUSE
NC score	0.017623 (rank : 93)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	556	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

SPEG_MOUSE
NC score	0.017557 (rank : 94)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	1959	Shared Neighborhood Hits	48
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ULK2_HUMAN
NC score	0.017507 (rank : 95)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	979	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

CEP68_MOUSE
NC score	0.015722 (rank : 96)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

MAST2_MOUSE
NC score	0.013929 (rank : 97)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	1110	Shared Neighborhood Hits	17
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

BAT4_MOUSE
NC score	0.013871 (rank : 98)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

LRRF2_HUMAN
NC score	0.013690 (rank : 99)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	791	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

MAST2_HUMAN
NC score	0.013370 (rank : 100)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	1189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TM16H_HUMAN
NC score	0.012540 (rank : 101)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

CSKI1_MOUSE
NC score	0.011681 (rank : 102)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	1031	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CTND2_MOUSE
NC score	0.011476 (rank : 103)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

ARBK1_MOUSE
NC score	0.011276 (rank : 104)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	849	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

ULK2_MOUSE
NC score	0.010917 (rank : 105)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	943	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

ARBK1_HUMAN
NC score	0.010782 (rank : 106)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	859	Shared Neighborhood Hits	11
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

SYCP1_HUMAN
NC score	0.009010 (rank : 107)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	1313	Shared Neighborhood Hits	11
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

DLGP2_MOUSE
NC score	0.008848 (rank : 108)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

GLI1_HUMAN
NC score	0.008702 (rank : 109)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	828	Shared Neighborhood Hits	17
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

TRIO_HUMAN
NC score	0.008437 (rank : 110)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	1580	Shared Neighborhood Hits	26
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

WDR33_HUMAN
NC score	0.007448 (rank : 111)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	638	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ZBT45_HUMAN
NC score	0.007308 (rank : 112)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	901	Shared Neighborhood Hits	19
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

CT075_HUMAN
NC score	0.006726 (rank : 113)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

HXD8_MOUSE
NC score	0.006272 (rank : 114)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	333	Shared Neighborhood Hits	4
SwissProt Accessions	P23463	Gene names	Hoxd8, Hox-4.3, Hoxd-8
Domain Architecture
Description	Homeobox protein Hox-D8 (Hox-4.3) (Hox-5.4).

T2R41_HUMAN
NC score	0.005916 (rank : 115)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	P59536, P59550	Gene names	TAS2R41
Domain Architecture
Description	Taste receptor type 2 member 41 (T2R41) (T2R59).

SDK1_HUMAN
NC score	0.005164 (rank : 116)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	511	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

LRC4B_HUMAN
NC score	0.002302 (rank : 117)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	479	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

NOTC2_MOUSE
NC score	0.001681 (rank : 118)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	1069	Shared Neighborhood Hits	14
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ZBT37_HUMAN
NC score	0.000244 (rank : 119)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	815	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.