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Network neighborhood for query Sequence : SPRE3_MOUSE

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SPRE3_MOUSE
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPRE3_MOUSE
θ value	4.72459e-150 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	111	Target Neighborhood Hits	111	Shared Neighborhood Hits	111
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE3_HUMAN
θ value	5.07123e-136 (rank : 2)	NC score	0.984363 (rank : 2)
Query Neighborhood Hits	111	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE2_MOUSE
θ value	6.96618e-77 (rank : 3)	NC score	0.927475 (rank : 3)
Query Neighborhood Hits	111	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q924S7	Gene names	Spred2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE2_HUMAN
θ value	8.51556e-75 (rank : 4)	NC score	0.925795 (rank : 4)
Query Neighborhood Hits	111	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z698, Q2NKX6	Gene names	SPRED2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE1_MOUSE
θ value	1.02001e-27 (rank : 5)	NC score	0.856817 (rank : 6)
Query Neighborhood Hits	111	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPRE1_HUMAN
θ value	6.61148e-27 (rank : 6)	NC score	0.856834 (rank : 5)
Query Neighborhood Hits	111	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z699, Q8N256	Gene names	SPRED1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPY3_HUMAN
θ value	5.08577e-11 (rank : 7)	NC score	0.568934 (rank : 7)
Query Neighborhood Hits	111	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

ENAH_MOUSE
θ value	3.29651e-10 (rank : 8)	NC score	0.407168 (rank : 18)
Query Neighborhood Hits	111	Target Neighborhood Hits	919	Shared Neighborhood Hits	48
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EVL_HUMAN
θ value	7.34386e-10 (rank : 9)	NC score	0.505881 (rank : 11)
Query Neighborhood Hits	111	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

ENAH_HUMAN
θ value	9.59137e-10 (rank : 10)	NC score	0.377991 (rank : 19)
Query Neighborhood Hits	111	Target Neighborhood Hits	784	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

SPY2_HUMAN
θ value	1.25267e-09 (rank : 11)	NC score	0.525775 (rank : 8)
Query Neighborhood Hits	111	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY2_MOUSE
θ value	1.25267e-09 (rank : 12)	NC score	0.525337 (rank : 9)
Query Neighborhood Hits	111	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

EVL_MOUSE
θ value	4.76016e-09 (rank : 13)	NC score	0.500768 (rank : 15)
Query Neighborhood Hits	111	Target Neighborhood Hits	203	Shared Neighborhood Hits	32
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SPY1_HUMAN
θ value	8.11959e-09 (rank : 14)	NC score	0.508247 (rank : 10)
Query Neighborhood Hits	111	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

SPY4_HUMAN
θ value	2.61198e-07 (rank : 15)	NC score	0.503147 (rank : 12)
Query Neighborhood Hits	111	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

SPY4_MOUSE
θ value	2.61198e-07 (rank : 16)	NC score	0.502247 (rank : 14)
Query Neighborhood Hits	111	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

VASP_MOUSE
θ value	1.29631e-06 (rank : 17)	NC score	0.502388 (rank : 13)
Query Neighborhood Hits	111	Target Neighborhood Hits	195	Shared Neighborhood Hits	30
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_HUMAN
θ value	1.87187e-05 (rank : 18)	NC score	0.485385 (rank : 16)
Query Neighborhood Hits	111	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPY1_MOUSE
θ value	0.00665767 (rank : 19)	NC score	0.449842 (rank : 17)
Query Neighborhood Hits	111	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

MUC1_HUMAN
θ value	0.0113563 (rank : 20)	NC score	0.064744 (rank : 26)
Query Neighborhood Hits	111	Target Neighborhood Hits	975	Shared Neighborhood Hits	47
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SON_HUMAN
θ value	0.0252991 (rank : 21)	NC score	0.062161 (rank : 29)
Query Neighborhood Hits	111	Target Neighborhood Hits	1568	Shared Neighborhood Hits	56
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PTN22_MOUSE
θ value	0.0330416 (rank : 22)	NC score	0.021158 (rank : 75)
Query Neighborhood Hits	111	Target Neighborhood Hits	179	Shared Neighborhood Hits	6
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

EPHA1_HUMAN
θ value	0.0563607 (rank : 23)	NC score	0.010850 (rank : 98)
Query Neighborhood Hits	111	Target Neighborhood Hits	997	Shared Neighborhood Hits	11
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

MAGE1_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.060373 (rank : 33)
Query Neighborhood Hits	111	Target Neighborhood Hits	1389	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MINT_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.054133 (rank : 40)
Query Neighborhood Hits	111	Target Neighborhood Hits	1514	Shared Neighborhood Hits	47
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NPAS4_HUMAN
θ value	0.125558 (rank : 26)	NC score	0.058302 (rank : 36)
Query Neighborhood Hits	111	Target Neighborhood Hits	214	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	0.125558 (rank : 27)	NC score	0.065378 (rank : 24)
Query Neighborhood Hits	111	Target Neighborhood Hits	245	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

CSF1_HUMAN
θ value	0.21417 (rank : 28)	NC score	0.059613 (rank : 34)
Query Neighborhood Hits	111	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

DBNL_MOUSE
θ value	0.21417 (rank : 29)	NC score	0.029331 (rank : 63)
Query Neighborhood Hits	111	Target Neighborhood Hits	306	Shared Neighborhood Hits	7
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

CIC_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.056258 (rank : 38)
Query Neighborhood Hits	111	Target Neighborhood Hits	992	Shared Neighborhood Hits	49
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DOT1L_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.061017 (rank : 30)
Query Neighborhood Hits	111	Target Neighborhood Hits	660	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

CABIN_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.060712 (rank : 32)
Query Neighborhood Hits	111	Target Neighborhood Hits	490	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

PCLO_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.046856 (rank : 44)
Query Neighborhood Hits	111	Target Neighborhood Hits	2275	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

UB7I4_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.041889 (rank : 48)
Query Neighborhood Hits	111	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

WASL_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.099153 (rank : 23)
Query Neighborhood Hits	111	Target Neighborhood Hits	312	Shared Neighborhood Hits	36
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.099869 (rank : 22)
Query Neighborhood Hits	111	Target Neighborhood Hits	339	Shared Neighborhood Hits	36
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZN385_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.060950 (rank : 31)
Query Neighborhood Hits	111	Target Neighborhood Hits	614	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

COFA1_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.034363 (rank : 56)
Query Neighborhood Hits	111	Target Neighborhood Hits	292	Shared Neighborhood Hits	22
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

A2BP1_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.024594 (rank : 69)
Query Neighborhood Hits	111	Target Neighborhood Hits	229	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NWB1, Q9NS20	Gene names	A2BP1, A2BP
Domain Architecture
Description	Ataxin-2-binding protein 1.

RP1L1_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.039224 (rank : 52)
Query Neighborhood Hits	111	Target Neighborhood Hits	1072	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

WASP_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.117277 (rank : 21)
Query Neighborhood Hits	111	Target Neighborhood Hits	195	Shared Neighborhood Hits	31
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.124793 (rank : 20)
Query Neighborhood Hits	111	Target Neighborhood Hits	223	Shared Neighborhood Hits	33
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

5NT1B_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.031617 (rank : 60)
Query Neighborhood Hits	111	Target Neighborhood Hits	78	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

PRRT3_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.059604 (rank : 35)
Query Neighborhood Hits	111	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

WASF3_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.034736 (rank : 55)
Query Neighborhood Hits	111	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

NFH_MOUSE
θ value	1.81305 (rank : 46)	NC score	0.029464 (rank : 62)
Query Neighborhood Hits	111	Target Neighborhood Hits	2247	Shared Neighborhood Hits	53
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SH2D5_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.027689 (rank : 65)
Query Neighborhood Hits	111	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZV89, Q5SSJ2	Gene names	SH2D5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

UB7I4_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.035919 (rank : 53)
Query Neighborhood Hits	111	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

EPHB4_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.004365 (rank : 110)
Query Neighborhood Hits	111	Target Neighborhood Hits	1056	Shared Neighborhood Hits	10
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

FOXL1_MOUSE
θ value	2.36792 (rank : 50)	NC score	0.016009 (rank : 81)
Query Neighborhood Hits	111	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

M3K1_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.003493 (rank : 111)
Query Neighborhood Hits	111	Target Neighborhood Hits	952	Shared Neighborhood Hits	15
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

PAX2_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.014952 (rank : 86)
Query Neighborhood Hits	111	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	P32114	Gene names	Pax2, Pax-2
Domain Architecture
Description	Paired box protein Pax-2.

PLXB3_MOUSE
θ value	2.36792 (rank : 53)	NC score	0.022202 (rank : 71)
Query Neighborhood Hits	111	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

SET1A_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.033047 (rank : 57)
Query Neighborhood Hits	111	Target Neighborhood Hits	690	Shared Neighborhood Hits	26
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TTBK1_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.010707 (rank : 100)
Query Neighborhood Hits	111	Target Neighborhood Hits	1058	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

A2BP1_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.021908 (rank : 72)
Query Neighborhood Hits	111	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJ43, Q9JJB5	Gene names	A2bp1, A2bp
Domain Architecture
Description	Ataxin-2-binding protein 1.

BAT3_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.046134 (rank : 46)
Query Neighborhood Hits	111	Target Neighborhood Hits	490	Shared Neighborhood Hits	36
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

MUC2_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.040507 (rank : 51)
Query Neighborhood Hits	111	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

RAVR1_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.015371 (rank : 83)
Query Neighborhood Hits	111	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

SHC2_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.010557 (rank : 101)
Query Neighborhood Hits	111	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SSBP4_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.035434 (rank : 54)
Query Neighborhood Hits	111	Target Neighborhood Hits	753	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

LRSM1_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.013775 (rank : 89)
Query Neighborhood Hits	111	Target Neighborhood Hits	1078	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MDC1_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.052209 (rank : 42)
Query Neighborhood Hits	111	Target Neighborhood Hits	1446	Shared Neighborhood Hits	49
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MK07_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.005043 (rank : 109)
Query Neighborhood Hits	111	Target Neighborhood Hits	1054	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MLL3_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.041006 (rank : 50)
Query Neighborhood Hits	111	Target Neighborhood Hits	1644	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MUCDL_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.044893 (rank : 47)
Query Neighborhood Hits	111	Target Neighborhood Hits	777	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NMDE4_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.011245 (rank : 97)
Query Neighborhood Hits	111	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

BAT2_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.046535 (rank : 45)
Query Neighborhood Hits	111	Target Neighborhood Hits	947	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.057209 (rank : 37)
Query Neighborhood Hits	111	Target Neighborhood Hits	2057	Shared Neighborhood Hits	67
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CNTN1_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.005294 (rank : 107)
Query Neighborhood Hits	111	Target Neighborhood Hits	431	Shared Neighborhood Hits	8
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CSKI2_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.019855 (rank : 76)
Query Neighborhood Hits	111	Target Neighborhood Hits	812	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FOXL2_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.009206 (rank : 106)
Query Neighborhood Hits	111	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

MYBPH_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.010170 (rank : 103)
Query Neighborhood Hits	111	Target Neighborhood Hits	290	Shared Neighborhood Hits	8
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NECD_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.018281 (rank : 78)
Query Neighborhood Hits	111	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

NIPA_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.027517 (rank : 66)
Query Neighborhood Hits	111	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

PAX2_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.013178 (rank : 92)
Query Neighborhood Hits	111	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q02962, Q15105, Q15110, Q15837	Gene names	PAX2
Domain Architecture
Description	Paired box protein Pax-2.

PI5PA_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.041233 (rank : 49)
Query Neighborhood Hits	111	Target Neighborhood Hits	749	Shared Neighborhood Hits	42
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SON_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.052983 (rank : 41)
Query Neighborhood Hits	111	Target Neighborhood Hits	957	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPEG_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.012452 (rank : 93)
Query Neighborhood Hits	111	Target Neighborhood Hits	1762	Shared Neighborhood Hits	54
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UBP28_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.011574 (rank : 94)
Query Neighborhood Hits	111	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

YPEL4_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.017864 (rank : 80)
Query Neighborhood Hits	111	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NS1, Q65Z98	Gene names	YPEL4
Domain Architecture
Description	Protein yippee-like 4.

ZEP1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.002959 (rank : 112)
Query Neighborhood Hits	111	Target Neighborhood Hits	1036	Shared Neighborhood Hits	15
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ANKK1_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.001756 (rank : 114)
Query Neighborhood Hits	111	Target Neighborhood Hits	1075	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

BAT2_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.055646 (rank : 39)
Query Neighborhood Hits	111	Target Neighborhood Hits	931	Shared Neighborhood Hits	46
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CENG1_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.010761 (rank : 99)
Query Neighborhood Hits	111	Target Neighborhood Hits	531	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

DAF1_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.009301 (rank : 105)
Query Neighborhood Hits	111	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DOCK3_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.011340 (rank : 96)
Query Neighborhood Hits	111	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.011419 (rank : 95)
Query Neighborhood Hits	111	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

IRS1_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.018127 (rank : 79)
Query Neighborhood Hits	111	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.021509 (rank : 73)
Query Neighborhood Hits	111	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

MAML1_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.018489 (rank : 77)
Query Neighborhood Hits	111	Target Neighborhood Hits	228	Shared Neighborhood Hits	14
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

OKL38_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.015246 (rank : 84)
Query Neighborhood Hits	111	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJX0, Q86UQ1, Q96S88, Q9BZ70	Gene names	OKL38
Domain Architecture
Description	Pregnancy-induced growth inhibitor OKL38 (huOKL38) (Ovary, kidney and liver protein 38).

REPS1_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.013278 (rank : 91)
Query Neighborhood Hits	111	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SMC4_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.002226 (rank : 113)
Query Neighborhood Hits	111	Target Neighborhood Hits	937	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SP5_HUMAN
θ value	6.88961 (rank : 95)	NC score	-0.000116 (rank : 115)
Query Neighborhood Hits	111	Target Neighborhood Hits	832	Shared Neighborhood Hits	16
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

TB182_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.028769 (rank : 64)
Query Neighborhood Hits	111	Target Neighborhood Hits	414	Shared Neighborhood Hits	23
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

YETS2_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.025031 (rank : 68)
Query Neighborhood Hits	111	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZC11A_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.015025 (rank : 85)
Query Neighborhood Hits	111	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

CENG1_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.010187 (rank : 102)
Query Neighborhood Hits	111	Target Neighborhood Hits	544	Shared Neighborhood Hits	17
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CJ108_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.021342 (rank : 74)
Query Neighborhood Hits	111	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

DOK2_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.025490 (rank : 67)
Query Neighborhood Hits	111	Target Neighborhood Hits	244	Shared Neighborhood Hits	18
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

FMN2_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.032783 (rank : 58)
Query Neighborhood Hits	111	Target Neighborhood Hits	484	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

IER2_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.015824 (rank : 82)
Query Neighborhood Hits	111	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

KCNK2_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.005079 (rank : 108)
Query Neighborhood Hits	111	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

MKL1_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.032700 (rank : 59)
Query Neighborhood Hits	111	Target Neighborhood Hits	667	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MNAB_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.014443 (rank : 87)
Query Neighborhood Hits	111	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.013615 (rank : 90)
Query Neighborhood Hits	111	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

PDLI7_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.009638 (rank : 104)
Query Neighborhood Hits	111	Target Neighborhood Hits	547	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD2_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.024478 (rank : 70)
Query Neighborhood Hits	111	Target Neighborhood Hits	772	Shared Neighborhood Hits	33
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PLXB3_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.013985 (rank : 88)
Query Neighborhood Hits	111	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PSL1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.030306 (rank : 61)
Query Neighborhood Hits	111	Target Neighborhood Hits	650	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

HOME3_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.063924 (rank : 27)
Query Neighborhood Hits	111	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

HOME3_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.065095 (rank : 25)
Query Neighborhood Hits	111	Target Neighborhood Hits	316	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

PTTG_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.063341 (rank : 28)
Query Neighborhood Hits	111	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R143, Q3TVT1, Q8BJ96, Q8N7P0	Gene names	Pttg1ip
Domain Architecture	No domain graphic available
Description	Pituitary tumor-transforming gene 1 protein-interacting protein precursor (Pituitary tumor-transforming gene protein-binding factor) (PTTG-binding factor) (PBF).

TAF4_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.050663 (rank : 43)
Query Neighborhood Hits	111	Target Neighborhood Hits	687	Shared Neighborhood Hits	40
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

Hits sorted by NC score

SPRE3_MOUSE
NC score	0.999962 (rank : 1)	θ value	4.72459e-150 (rank : 1)
Query Neighborhood Hits	111	Target Neighborhood Hits	111	Shared Neighborhood Hits	111
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE3_HUMAN
NC score	0.984363 (rank : 2)	θ value	5.07123e-136 (rank : 2)
Query Neighborhood Hits	111	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE2_MOUSE
NC score	0.927475 (rank : 3)	θ value	6.96618e-77 (rank : 3)
Query Neighborhood Hits	111	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q924S7	Gene names	Spred2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE2_HUMAN
NC score	0.925795 (rank : 4)	θ value	8.51556e-75 (rank : 4)
Query Neighborhood Hits	111	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z698, Q2NKX6	Gene names	SPRED2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE1_HUMAN
NC score	0.856834 (rank : 5)	θ value	6.61148e-27 (rank : 6)
Query Neighborhood Hits	111	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z699, Q8N256	Gene names	SPRED1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPRE1_MOUSE
NC score	0.856817 (rank : 6)	θ value	1.02001e-27 (rank : 5)
Query Neighborhood Hits	111	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPY3_HUMAN
NC score	0.568934 (rank : 7)	θ value	5.08577e-11 (rank : 7)
Query Neighborhood Hits	111	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

SPY2_HUMAN
NC score	0.525775 (rank : 8)	θ value	1.25267e-09 (rank : 11)
Query Neighborhood Hits	111	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY2_MOUSE
NC score	0.525337 (rank : 9)	θ value	1.25267e-09 (rank : 12)
Query Neighborhood Hits	111	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY1_HUMAN
NC score	0.508247 (rank : 10)	θ value	8.11959e-09 (rank : 14)
Query Neighborhood Hits	111	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

EVL_HUMAN
NC score	0.505881 (rank : 11)	θ value	7.34386e-10 (rank : 9)
Query Neighborhood Hits	111	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SPY4_HUMAN
NC score	0.503147 (rank : 12)	θ value	2.61198e-07 (rank : 15)
Query Neighborhood Hits	111	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

VASP_MOUSE
NC score	0.502388 (rank : 13)	θ value	1.29631e-06 (rank : 17)
Query Neighborhood Hits	111	Target Neighborhood Hits	195	Shared Neighborhood Hits	30
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPY4_MOUSE
NC score	0.502247 (rank : 14)	θ value	2.61198e-07 (rank : 16)
Query Neighborhood Hits	111	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

EVL_MOUSE
NC score	0.500768 (rank : 15)	θ value	4.76016e-09 (rank : 13)
Query Neighborhood Hits	111	Target Neighborhood Hits	203	Shared Neighborhood Hits	32
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

VASP_HUMAN
NC score	0.485385 (rank : 16)	θ value	1.87187e-05 (rank : 18)
Query Neighborhood Hits	111	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPY1_MOUSE
NC score	0.449842 (rank : 17)	θ value	0.00665767 (rank : 19)
Query Neighborhood Hits	111	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

ENAH_MOUSE
NC score	0.407168 (rank : 18)	θ value	3.29651e-10 (rank : 8)
Query Neighborhood Hits	111	Target Neighborhood Hits	919	Shared Neighborhood Hits	48
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENAH_HUMAN
NC score	0.377991 (rank : 19)	θ value	9.59137e-10 (rank : 10)
Query Neighborhood Hits	111	Target Neighborhood Hits	784	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

WASP_MOUSE
NC score	0.124793 (rank : 20)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	111	Target Neighborhood Hits	223	Shared Neighborhood Hits	33
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WASP_HUMAN
NC score	0.117277 (rank : 21)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	111	Target Neighborhood Hits	195	Shared Neighborhood Hits	31
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASL_MOUSE
NC score	0.099869 (rank : 22)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	111	Target Neighborhood Hits	339	Shared Neighborhood Hits	36
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_HUMAN
NC score	0.099153 (rank : 23)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	111	Target Neighborhood Hits	312	Shared Neighborhood Hits	36
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

NPAS4_MOUSE
NC score	0.065378 (rank : 24)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	111	Target Neighborhood Hits	245	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

HOME3_MOUSE
NC score	0.065095 (rank : 25)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	111	Target Neighborhood Hits	316	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

MUC1_HUMAN
NC score	0.064744 (rank : 26)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	111	Target Neighborhood Hits	975	Shared Neighborhood Hits	47
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

HOME3_HUMAN
NC score	0.063924 (rank : 27)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	111	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

PTTG_MOUSE
NC score	0.063341 (rank : 28)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	111	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R143, Q3TVT1, Q8BJ96, Q8N7P0	Gene names	Pttg1ip
Domain Architecture	No domain graphic available
Description	Pituitary tumor-transforming gene 1 protein-interacting protein precursor (Pituitary tumor-transforming gene protein-binding factor) (PTTG-binding factor) (PBF).

SON_HUMAN
NC score	0.062161 (rank : 29)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	111	Target Neighborhood Hits	1568	Shared Neighborhood Hits	56
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DOT1L_HUMAN
NC score	0.061017 (rank : 30)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	111	Target Neighborhood Hits	660	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

ZN385_HUMAN
NC score	0.060950 (rank : 31)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	111	Target Neighborhood Hits	614	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CABIN_HUMAN
NC score	0.060712 (rank : 32)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	111	Target Neighborhood Hits	490	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

MAGE1_HUMAN
NC score	0.060373 (rank : 33)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	111	Target Neighborhood Hits	1389	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CSF1_HUMAN
NC score	0.059613 (rank : 34)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	111	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

PRRT3_HUMAN
NC score	0.059604 (rank : 35)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	111	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

NPAS4_HUMAN
NC score	0.058302 (rank : 36)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	111	Target Neighborhood Hits	214	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

BSN_MOUSE
NC score	0.057209 (rank : 37)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	111	Target Neighborhood Hits	2057	Shared Neighborhood Hits	67
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CIC_HUMAN
NC score	0.056258 (rank : 38)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	111	Target Neighborhood Hits	992	Shared Neighborhood Hits	49
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BAT2_HUMAN
NC score	0.055646 (rank : 39)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	111	Target Neighborhood Hits	931	Shared Neighborhood Hits	46
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MINT_MOUSE
NC score	0.054133 (rank : 40)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	111	Target Neighborhood Hits	1514	Shared Neighborhood Hits	47
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SON_MOUSE
NC score	0.052983 (rank : 41)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	111	Target Neighborhood Hits	957	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MDC1_HUMAN
NC score	0.052209 (rank : 42)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	111	Target Neighborhood Hits	1446	Shared Neighborhood Hits	49
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TAF4_HUMAN
NC score	0.050663 (rank : 43)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	111	Target Neighborhood Hits	687	Shared Neighborhood Hits	40
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PCLO_MOUSE
NC score	0.046856 (rank : 44)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	111	Target Neighborhood Hits	2275	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

BAT2_MOUSE
NC score	0.046535 (rank : 45)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	111	Target Neighborhood Hits	947	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT3_HUMAN
NC score	0.046134 (rank : 46)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	111	Target Neighborhood Hits	490	Shared Neighborhood Hits	36
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

MUCDL_HUMAN
NC score	0.044893 (rank : 47)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	111	Target Neighborhood Hits	777	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

UB7I4_HUMAN
NC score	0.041889 (rank : 48)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	111	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

PI5PA_HUMAN
NC score	0.041233 (rank : 49)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	111	Target Neighborhood Hits	749	Shared Neighborhood Hits	42
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MLL3_HUMAN
NC score	0.041006 (rank : 50)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	111	Target Neighborhood Hits	1644	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MUC2_HUMAN
NC score	0.040507 (rank : 51)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	111	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

RP1L1_HUMAN
NC score	0.039224 (rank : 52)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	111	Target Neighborhood Hits	1072	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

UB7I4_MOUSE
NC score	0.035919 (rank : 53)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	111	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

SSBP4_HUMAN
NC score	0.035434 (rank : 54)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	111	Target Neighborhood Hits	753	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

WASF3_HUMAN
NC score	0.034736 (rank : 55)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	111	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

COFA1_HUMAN
NC score	0.034363 (rank : 56)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	111	Target Neighborhood Hits	292	Shared Neighborhood Hits	22
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

SET1A_HUMAN
NC score	0.033047 (rank : 57)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	111	Target Neighborhood Hits	690	Shared Neighborhood Hits	26
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

FMN2_HUMAN
NC score	0.032783 (rank : 58)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	111	Target Neighborhood Hits	484	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MKL1_MOUSE
NC score	0.032700 (rank : 59)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	111	Target Neighborhood Hits	667	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

5NT1B_MOUSE
NC score	0.031617 (rank : 60)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	111	Target Neighborhood Hits	78	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

PSL1_HUMAN
NC score	0.030306 (rank : 61)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	111	Target Neighborhood Hits	650	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

NFH_MOUSE
NC score	0.029464 (rank : 62)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	111	Target Neighborhood Hits	2247	Shared Neighborhood Hits	53
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DBNL_MOUSE
NC score	0.029331 (rank : 63)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	111	Target Neighborhood Hits	306	Shared Neighborhood Hits	7
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

TB182_HUMAN
NC score	0.028769 (rank : 64)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	111	Target Neighborhood Hits	414	Shared Neighborhood Hits	23
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

SH2D5_HUMAN
NC score	0.027689 (rank : 65)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	111	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZV89, Q5SSJ2	Gene names	SH2D5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

NIPA_HUMAN
NC score	0.027517 (rank : 66)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	111	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

DOK2_MOUSE
NC score	0.025490 (rank : 67)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	111	Target Neighborhood Hits	244	Shared Neighborhood Hits	18
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

YETS2_HUMAN
NC score	0.025031 (rank : 68)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	111	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

A2BP1_HUMAN
NC score	0.024594 (rank : 69)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	111	Target Neighborhood Hits	229	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NWB1, Q9NS20	Gene names	A2BP1, A2BP
Domain Architecture
Description	Ataxin-2-binding protein 1.

PDZD2_HUMAN
NC score	0.024478 (rank : 70)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	111	Target Neighborhood Hits	772	Shared Neighborhood Hits	33
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PLXB3_MOUSE
NC score	0.022202 (rank : 71)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	111	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

A2BP1_MOUSE
NC score	0.021908 (rank : 72)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	111	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJ43, Q9JJB5	Gene names	A2bp1, A2bp
Domain Architecture
Description	Ataxin-2-binding protein 1.

IRS1_MOUSE
NC score	0.021509 (rank : 73)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	111	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

CJ108_HUMAN
NC score	0.021342 (rank : 74)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	111	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

PTN22_MOUSE
NC score	0.021158 (rank : 75)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	111	Target Neighborhood Hits	179	Shared Neighborhood Hits	6
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

CSKI2_MOUSE
NC score	0.019855 (rank : 76)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	111	Target Neighborhood Hits	812	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MAML1_HUMAN
NC score	0.018489 (rank : 77)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	111	Target Neighborhood Hits	228	Shared Neighborhood Hits	14
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

NECD_MOUSE
NC score	0.018281 (rank : 78)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	111	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	P25233, Q542W7, Q61951	Gene names	Ndn
Domain Architecture
Description	Necdin.

IRS1_HUMAN
NC score	0.018127 (rank : 79)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	111	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

YPEL4_HUMAN
NC score	0.017864 (rank : 80)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	111	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NS1, Q65Z98	Gene names	YPEL4
Domain Architecture
Description	Protein yippee-like 4.

FOXL1_MOUSE
NC score	0.016009 (rank : 81)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	111	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

IER2_HUMAN
NC score	0.015824 (rank : 82)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	111	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

RAVR1_MOUSE
NC score	0.015371 (rank : 83)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	111	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

OKL38_HUMAN
NC score	0.015246 (rank : 84)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	111	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJX0, Q86UQ1, Q96S88, Q9BZ70	Gene names	OKL38
Domain Architecture
Description	Pregnancy-induced growth inhibitor OKL38 (huOKL38) (Ovary, kidney and liver protein 38).

ZC11A_MOUSE
NC score	0.015025 (rank : 85)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	111	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

PAX2_MOUSE
NC score	0.014952 (rank : 86)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	111	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	P32114	Gene names	Pax2, Pax-2
Domain Architecture
Description	Paired box protein Pax-2.

MNAB_HUMAN
NC score	0.014443 (rank : 87)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	111	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

PLXB3_HUMAN
NC score	0.013985 (rank : 88)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	111	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

LRSM1_HUMAN
NC score	0.013775 (rank : 89)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	111	Target Neighborhood Hits	1078	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MNAB_MOUSE
NC score	0.013615 (rank : 90)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	111	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

REPS1_MOUSE
NC score	0.013278 (rank : 91)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	111	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

PAX2_HUMAN
NC score	0.013178 (rank : 92)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	111	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q02962, Q15105, Q15110, Q15837	Gene names	PAX2
Domain Architecture
Description	Paired box protein Pax-2.

SPEG_HUMAN
NC score	0.012452 (rank : 93)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	111	Target Neighborhood Hits	1762	Shared Neighborhood Hits	54
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UBP28_MOUSE
NC score	0.011574 (rank : 94)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	111	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

DOCK3_MOUSE
NC score	0.011419 (rank : 95)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	111	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_HUMAN
NC score	0.011340 (rank : 96)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	111	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

NMDE4_MOUSE
NC score	0.011245 (rank : 97)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	111	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

EPHA1_HUMAN
NC score	0.010850 (rank : 98)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	111	Target Neighborhood Hits	997	Shared Neighborhood Hits	11
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

CENG1_MOUSE
NC score	0.010761 (rank : 99)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	111	Target Neighborhood Hits	531	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

TTBK1_HUMAN
NC score	0.010707 (rank : 100)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	111	Target Neighborhood Hits	1058	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

SHC2_HUMAN
NC score	0.010557 (rank : 101)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	111	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

CENG1_HUMAN
NC score	0.010187 (rank : 102)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	111	Target Neighborhood Hits	544	Shared Neighborhood Hits	17
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

MYBPH_MOUSE
NC score	0.010170 (rank : 103)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	111	Target Neighborhood Hits	290	Shared Neighborhood Hits	8
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

PDLI7_HUMAN
NC score	0.009638 (rank : 104)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	111	Target Neighborhood Hits	547	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

DAF1_MOUSE
NC score	0.009301 (rank : 105)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	111	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

FOXL2_HUMAN
NC score	0.009206 (rank : 106)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	111	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

CNTN1_HUMAN
NC score	0.005294 (rank : 107)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	111	Target Neighborhood Hits	431	Shared Neighborhood Hits	8
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

KCNK2_MOUSE
NC score	0.005079 (rank : 108)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	111	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

MK07_MOUSE
NC score	0.005043 (rank : 109)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	111	Target Neighborhood Hits	1054	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

EPHB4_HUMAN
NC score	0.004365 (rank : 110)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	111	Target Neighborhood Hits	1056	Shared Neighborhood Hits	10
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

M3K1_MOUSE
NC score	0.003493 (rank : 111)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	111	Target Neighborhood Hits	952	Shared Neighborhood Hits	15
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

ZEP1_HUMAN
NC score	0.002959 (rank : 112)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	111	Target Neighborhood Hits	1036	Shared Neighborhood Hits	15
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

SMC4_HUMAN
NC score	0.002226 (rank : 113)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	111	Target Neighborhood Hits	937	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

ANKK1_HUMAN
NC score	0.001756 (rank : 114)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	111	Target Neighborhood Hits	1075	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

SP5_HUMAN
NC score	-0.000116 (rank : 115)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	111	Target Neighborhood Hits	832	Shared Neighborhood Hits	16
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.