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Network neighborhood for query Sequence : SH2D5_HUMAN

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SH2D5_HUMAN
SwissProt Accessions	Q6ZV89, Q5SSJ2	Gene names	SH2D5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SH2D5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	28	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZV89, Q5SSJ2	Gene names	SH2D5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

SH2D5_MOUSE
θ value	8.02161e-166 (rank : 2)	NC score	0.983546 (rank : 2)
Query Neighborhood Hits	28	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8JZW5	Gene names	Sh2d5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

SRMS_MOUSE
θ value	0.00869519 (rank : 3)	NC score	0.049276 (rank : 22)
Query Neighborhood Hits	28	Target Neighborhood Hits	964	Shared Neighborhood Hits	20
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

TENS1_HUMAN
θ value	0.0193708 (rank : 4)	NC score	0.099101 (rank : 8)
Query Neighborhood Hits	28	Target Neighborhood Hits	400	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

GRAP2_MOUSE
θ value	0.0330416 (rank : 5)	NC score	0.126558 (rank : 5)
Query Neighborhood Hits	28	Target Neighborhood Hits	297	Shared Neighborhood Hits	21
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

SRMS_HUMAN
θ value	0.0330416 (rank : 6)	NC score	0.047552 (rank : 23)
Query Neighborhood Hits	28	Target Neighborhood Hits	946	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

GRAP2_HUMAN
θ value	0.0563607 (rank : 7)	NC score	0.128006 (rank : 4)
Query Neighborhood Hits	28	Target Neighborhood Hits	304	Shared Neighborhood Hits	21
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GOGA3_HUMAN
θ value	0.0961366 (rank : 8)	NC score	0.019734 (rank : 34)
Query Neighborhood Hits	28	Target Neighborhood Hits	1317	Shared Neighborhood Hits	2
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

SH21B_MOUSE
θ value	0.125558 (rank : 9)	NC score	0.134145 (rank : 3)
Query Neighborhood Hits	28	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

PTK6_MOUSE
θ value	0.163984 (rank : 10)	NC score	0.042694 (rank : 25)
Query Neighborhood Hits	28	Target Neighborhood Hits	1026	Shared Neighborhood Hits	19
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

GRB2_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.103169 (rank : 6)
Query Neighborhood Hits	28	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	0.62314 (rank : 12)	NC score	0.103103 (rank : 7)
Query Neighborhood Hits	28	Target Neighborhood Hits	312	Shared Neighborhood Hits	21
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

SLAP2_MOUSE
θ value	0.62314 (rank : 13)	NC score	0.097550 (rank : 10)
Query Neighborhood Hits	28	Target Neighborhood Hits	136	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

PTK6_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.038586 (rank : 27)
Query Neighborhood Hits	28	Target Neighborhood Hits	1020	Shared Neighborhood Hits	20
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

GRAP_MOUSE
θ value	1.06291 (rank : 15)	NC score	0.094253 (rank : 11)
Query Neighborhood Hits	28	Target Neighborhood Hits	309	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SLAP2_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.097711 (rank : 9)
Query Neighborhood Hits	28	Target Neighborhood Hits	139	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

GRAP_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.092883 (rank : 13)
Query Neighborhood Hits	28	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SHC2_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.046834 (rank : 24)
Query Neighborhood Hits	28	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SPRE3_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.027689 (rank : 32)
Query Neighborhood Hits	28	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

ABL1_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.035747 (rank : 28)
Query Neighborhood Hits	28	Target Neighborhood Hits	1220	Shared Neighborhood Hits	20
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.035673 (rank : 29)
Query Neighborhood Hits	28	Target Neighborhood Hits	1178	Shared Neighborhood Hits	20
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

RERE_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.016086 (rank : 35)
Query Neighborhood Hits	28	Target Neighborhood Hits	779	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SH21B_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.093407 (rank : 12)
Query Neighborhood Hits	28	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

ABL2_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.039488 (rank : 26)
Query Neighborhood Hits	28	Target Neighborhood Hits	1045	Shared Neighborhood Hits	21
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

UBTD1_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.032748 (rank : 30)
Query Neighborhood Hits	28	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HAC8, Q53HI3	Gene names	UBTD1
Domain Architecture	No domain graphic available
Description	Ubiquitin domain-containing protein 1.

UBTD1_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.031018 (rank : 31)
Query Neighborhood Hits	28	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WB7	Gene names	Ubtd1
Domain Architecture	No domain graphic available
Description	Ubiquitin domain-containing protein 1.

CC024_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.024486 (rank : 33)
Query Neighborhood Hits	28	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D4K4, Q80XT0, Q80Y40	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf24 homolog.

TNR3_MOUSE
θ value	8.99809 (rank : 28)	NC score	0.010672 (rank : 36)
Query Neighborhood Hits	28	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

APS_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.050553 (rank : 21)
Query Neighborhood Hits	28	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

HSH2D_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.055162 (rank : 17)
Query Neighborhood Hits	28	Target Neighborhood Hits	159	Shared Neighborhood Hits	15
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

NCK1_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.057056 (rank : 16)
Query Neighborhood Hits	28	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.052687 (rank : 20)
Query Neighborhood Hits	28	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

SH21A_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.053228 (rank : 19)
Query Neighborhood Hits	28	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.054514 (rank : 18)
Query Neighborhood Hits	28	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SLAP1_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.071388 (rank : 15)
Query Neighborhood Hits	28	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.071862 (rank : 14)
Query Neighborhood Hits	28	Target Neighborhood Hits	117	Shared Neighborhood Hits	17
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

Hits sorted by NC score

SH2D5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	28	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZV89, Q5SSJ2	Gene names	SH2D5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

SH2D5_MOUSE
NC score	0.983546 (rank : 2)	θ value	8.02161e-166 (rank : 2)
Query Neighborhood Hits	28	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8JZW5	Gene names	Sh2d5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

SH21B_MOUSE
NC score	0.134145 (rank : 3)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	28	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

GRAP2_HUMAN
NC score	0.128006 (rank : 4)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	28	Target Neighborhood Hits	304	Shared Neighborhood Hits	21
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
NC score	0.126558 (rank : 5)	θ value	0.0330416 (rank : 5)
Query Neighborhood Hits	28	Target Neighborhood Hits	297	Shared Neighborhood Hits	21
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRB2_HUMAN
NC score	0.103169 (rank : 6)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	28	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.103103 (rank : 7)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	28	Target Neighborhood Hits	312	Shared Neighborhood Hits	21
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

TENS1_HUMAN
NC score	0.099101 (rank : 8)	θ value	0.0193708 (rank : 4)
Query Neighborhood Hits	28	Target Neighborhood Hits	400	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

SLAP2_HUMAN
NC score	0.097711 (rank : 9)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	28	Target Neighborhood Hits	139	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
NC score	0.097550 (rank : 10)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	28	Target Neighborhood Hits	136	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

GRAP_MOUSE
NC score	0.094253 (rank : 11)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	28	Target Neighborhood Hits	309	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SH21B_HUMAN
NC score	0.093407 (rank : 12)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	28	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

GRAP_HUMAN
NC score	0.092883 (rank : 13)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	28	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SLAP1_MOUSE
NC score	0.071862 (rank : 14)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	28	Target Neighborhood Hits	117	Shared Neighborhood Hits	17
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP1_HUMAN
NC score	0.071388 (rank : 15)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	28	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

NCK1_HUMAN
NC score	0.057056 (rank : 16)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	28	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

HSH2D_HUMAN
NC score	0.055162 (rank : 17)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	28	Target Neighborhood Hits	159	Shared Neighborhood Hits	15
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

SH21A_MOUSE
NC score	0.054514 (rank : 18)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	28	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21A_HUMAN
NC score	0.053228 (rank : 19)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	28	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

NCK2_HUMAN
NC score	0.052687 (rank : 20)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	28	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

APS_HUMAN
NC score	0.050553 (rank : 21)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	28	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

SRMS_MOUSE
NC score	0.049276 (rank : 22)	θ value	0.00869519 (rank : 3)
Query Neighborhood Hits	28	Target Neighborhood Hits	964	Shared Neighborhood Hits	20
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SRMS_HUMAN
NC score	0.047552 (rank : 23)	θ value	0.0330416 (rank : 6)
Query Neighborhood Hits	28	Target Neighborhood Hits	946	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SHC2_MOUSE
NC score	0.046834 (rank : 24)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	28	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

PTK6_MOUSE
NC score	0.042694 (rank : 25)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	28	Target Neighborhood Hits	1026	Shared Neighborhood Hits	19
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

ABL2_HUMAN
NC score	0.039488 (rank : 26)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	28	Target Neighborhood Hits	1045	Shared Neighborhood Hits	21
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

PTK6_HUMAN
NC score	0.038586 (rank : 27)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	28	Target Neighborhood Hits	1020	Shared Neighborhood Hits	20
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

ABL1_HUMAN
NC score	0.035747 (rank : 28)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	28	Target Neighborhood Hits	1220	Shared Neighborhood Hits	20
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
NC score	0.035673 (rank : 29)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	28	Target Neighborhood Hits	1178	Shared Neighborhood Hits	20
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

UBTD1_HUMAN
NC score	0.032748 (rank : 30)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	28	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HAC8, Q53HI3	Gene names	UBTD1
Domain Architecture	No domain graphic available
Description	Ubiquitin domain-containing protein 1.

UBTD1_MOUSE
NC score	0.031018 (rank : 31)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	28	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WB7	Gene names	Ubtd1
Domain Architecture	No domain graphic available
Description	Ubiquitin domain-containing protein 1.

SPRE3_MOUSE
NC score	0.027689 (rank : 32)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	28	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

CC024_MOUSE
NC score	0.024486 (rank : 33)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	28	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D4K4, Q80XT0, Q80Y40	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf24 homolog.

GOGA3_HUMAN
NC score	0.019734 (rank : 34)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	28	Target Neighborhood Hits	1317	Shared Neighborhood Hits	2
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

RERE_HUMAN
NC score	0.016086 (rank : 35)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	28	Target Neighborhood Hits	779	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

TNR3_MOUSE
NC score	0.010672 (rank : 36)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	28	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).