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Network neighborhood for query Sequence : SPRE3_HUMAN

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SPRE3_HUMAN
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPRE3_MOUSE
θ value	5.07123e-136 (rank : 1)	NC score	0.984363 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	111	Shared Neighborhood Hits	49
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE3_HUMAN
θ value	9.58617e-127 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE2_MOUSE
θ value	4.22625e-74 (rank : 3)	NC score	0.938231 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q924S7	Gene names	Spred2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE2_HUMAN
θ value	7.97034e-73 (rank : 4)	NC score	0.936620 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z698, Q2NKX6	Gene names	SPRED2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE1_MOUSE
θ value	1.02001e-27 (rank : 5)	NC score	0.869022 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPRE1_HUMAN
θ value	6.61148e-27 (rank : 6)	NC score	0.869107 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z699, Q8N256	Gene names	SPRED1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPY3_HUMAN
θ value	5.08577e-11 (rank : 7)	NC score	0.577843 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

ENAH_MOUSE
θ value	3.29651e-10 (rank : 8)	NC score	0.400625 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	919	Shared Neighborhood Hits	33
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EVL_HUMAN
θ value	7.34386e-10 (rank : 9)	NC score	0.512948 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	260	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

ENAH_HUMAN
θ value	9.59137e-10 (rank : 10)	NC score	0.381146 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	784	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

SPY2_HUMAN
θ value	1.25267e-09 (rank : 11)	NC score	0.534470 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY2_MOUSE
θ value	1.25267e-09 (rank : 12)	NC score	0.534382 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

EVL_MOUSE
θ value	3.64472e-09 (rank : 13)	NC score	0.506093 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	203	Shared Neighborhood Hits	24
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SPY1_HUMAN
θ value	8.11959e-09 (rank : 14)	NC score	0.516723 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

SPY4_HUMAN
θ value	2.61198e-07 (rank : 15)	NC score	0.511676 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

SPY4_MOUSE
θ value	2.61198e-07 (rank : 16)	NC score	0.510764 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

VASP_MOUSE
θ value	1.29631e-06 (rank : 17)	NC score	0.502158 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_HUMAN
θ value	1.43324e-05 (rank : 18)	NC score	0.484032 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPY1_MOUSE
θ value	0.00665767 (rank : 19)	NC score	0.458393 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

PHLB1_HUMAN
θ value	0.0563607 (rank : 20)	NC score	0.040789 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	1038	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SPEG_HUMAN
θ value	0.0563607 (rank : 21)	NC score	0.014102 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	1762	Shared Neighborhood Hits	31
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

EPHA1_HUMAN
θ value	0.0736092 (rank : 22)	NC score	0.009527 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	997	Shared Neighborhood Hits	7
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

MAGE1_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.043396 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	1389	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MUC1_HUMAN
θ value	0.163984 (rank : 24)	NC score	0.048241 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

FOXL1_MOUSE
θ value	0.279714 (rank : 25)	NC score	0.017825 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

MINT_MOUSE
θ value	0.365318 (rank : 26)	NC score	0.042765 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	1514	Shared Neighborhood Hits	27
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PDZD2_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.030556 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	772	Shared Neighborhood Hits	19
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

UB7I4_HUMAN
θ value	0.47712 (rank : 28)	NC score	0.044028 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

MLL3_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.040987 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	1644	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RP1L1_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.036868 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	1072	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

LRSM1_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.017699 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	1078	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

WASL_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.088354 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	312	Shared Neighborhood Hits	26
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	1.06291 (rank : 33)	NC score	0.087728 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	339	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.107688 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.114864 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

MBB1A_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.035002 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	665	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PCLO_MOUSE
θ value	1.38821 (rank : 37)	NC score	0.036123 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	2275	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

UB7I4_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.038013 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

GIT2_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.012235 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	323	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

TXLNG_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.010489 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	568	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

BSN_MOUSE
θ value	2.36792 (rank : 41)	NC score	0.046799 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	2057	Shared Neighborhood Hits	39
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PLXB3_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.022669 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

YPEL4_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.020131 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NS1, Q65Z98	Gene names	YPEL4
Domain Architecture
Description	Protein yippee-like 4.

NIPA_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.029889 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

ZN385_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.051265 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	614	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ANK2_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.009124 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	1615	Shared Neighborhood Hits	30
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CNTN1_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.007241 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	431	Shared Neighborhood Hits	6
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

DOK2_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.025948 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	244	Shared Neighborhood Hits	10
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

ANKK1_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.002414 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	1075	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

CABIN_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.038905 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	490	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CU124_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.024123 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q96HW9	Gene names	C21orf124
Domain Architecture	No domain graphic available
Description	Protein C21orf124.

FBX46_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.013721 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

JADE2_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.010274 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

MADCA_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.015323 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q61826, O35530, Q61278, Q64275, Q8R1M6	Gene names	Madcam1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (mMAdCAM-1).

MLL3_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.029209 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	1399	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NPAS4_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.028581 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	245	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

YETS2_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.019651 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

BEGIN_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.009043 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	383	Shared Neighborhood Hits	6
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CAC1G_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.012076 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	587	Shared Neighborhood Hits	23
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CO4A2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.006751 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	492	Shared Neighborhood Hits	13
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

HXD1_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.000963 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

PLXB3_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.014403 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

SRRM1_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.041939 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	966	Shared Neighborhood Hits	25
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TAOK2_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.002392 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	1373	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

TTBK1_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.006040 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	1058	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

HOME3_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.066278 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

HOME3_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.067940 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	316	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

PTTG_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.064146 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R143, Q3TVT1, Q8BJ96, Q8N7P0	Gene names	Pttg1ip
Domain Architecture	No domain graphic available
Description	Pituitary tumor-transforming gene 1 protein-interacting protein precursor (Pituitary tumor-transforming gene protein-binding factor) (PTTG-binding factor) (PBF).

Hits sorted by NC score

SPRE3_HUMAN
NC score	0.999962 (rank : 1)	θ value	9.58617e-127 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE3_MOUSE
NC score	0.984363 (rank : 2)	θ value	5.07123e-136 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	111	Shared Neighborhood Hits	49
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SPRE2_MOUSE
NC score	0.938231 (rank : 3)	θ value	4.22625e-74 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q924S7	Gene names	Spred2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE2_HUMAN
NC score	0.936620 (rank : 4)	θ value	7.97034e-73 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z698, Q2NKX6	Gene names	SPRED2
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2).

SPRE1_HUMAN
NC score	0.869107 (rank : 5)	θ value	6.61148e-27 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z699, Q8N256	Gene names	SPRED1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPRE1_MOUSE
NC score	0.869022 (rank : 6)	θ value	1.02001e-27 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SPY3_HUMAN
NC score	0.577843 (rank : 7)	θ value	5.08577e-11 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

SPY2_HUMAN
NC score	0.534470 (rank : 8)	θ value	1.25267e-09 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY2_MOUSE
NC score	0.534382 (rank : 9)	θ value	1.25267e-09 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY1_HUMAN
NC score	0.516723 (rank : 10)	θ value	8.11959e-09 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

EVL_HUMAN
NC score	0.512948 (rank : 11)	θ value	7.34386e-10 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	260	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SPY4_HUMAN
NC score	0.511676 (rank : 12)	θ value	2.61198e-07 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

SPY4_MOUSE
NC score	0.510764 (rank : 13)	θ value	2.61198e-07 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

EVL_MOUSE
NC score	0.506093 (rank : 14)	θ value	3.64472e-09 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	203	Shared Neighborhood Hits	24
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

VASP_MOUSE
NC score	0.502158 (rank : 15)	θ value	1.29631e-06 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_HUMAN
NC score	0.484032 (rank : 16)	θ value	1.43324e-05 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPY1_MOUSE
NC score	0.458393 (rank : 17)	θ value	0.00665767 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

ENAH_MOUSE
NC score	0.400625 (rank : 18)	θ value	3.29651e-10 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	919	Shared Neighborhood Hits	33
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENAH_HUMAN
NC score	0.381146 (rank : 19)	θ value	9.59137e-10 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	784	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

WASP_MOUSE
NC score	0.114864 (rank : 20)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WASP_HUMAN
NC score	0.107688 (rank : 21)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASL_HUMAN
NC score	0.088354 (rank : 22)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	312	Shared Neighborhood Hits	26
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
NC score	0.087728 (rank : 23)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	339	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

HOME3_MOUSE
NC score	0.067940 (rank : 24)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	316	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

HOME3_HUMAN
NC score	0.066278 (rank : 25)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSC5, O14580, O95350, Q9NSB9, Q9NSC0	Gene names	HOMER3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

PTTG_MOUSE
NC score	0.064146 (rank : 26)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R143, Q3TVT1, Q8BJ96, Q8N7P0	Gene names	Pttg1ip
Domain Architecture	No domain graphic available
Description	Pituitary tumor-transforming gene 1 protein-interacting protein precursor (Pituitary tumor-transforming gene protein-binding factor) (PTTG-binding factor) (PBF).

ZN385_HUMAN
NC score	0.051265 (rank : 27)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	614	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

MUC1_HUMAN
NC score	0.048241 (rank : 28)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

BSN_MOUSE
NC score	0.046799 (rank : 29)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	2057	Shared Neighborhood Hits	39
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

UB7I4_HUMAN
NC score	0.044028 (rank : 30)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

MAGE1_HUMAN
NC score	0.043396 (rank : 31)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	1389	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MINT_MOUSE
NC score	0.042765 (rank : 32)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	1514	Shared Neighborhood Hits	27
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SRRM1_MOUSE
NC score	0.041939 (rank : 33)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	966	Shared Neighborhood Hits	25
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MLL3_HUMAN
NC score	0.040987 (rank : 34)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	1644	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PHLB1_HUMAN
NC score	0.040789 (rank : 35)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	1038	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CABIN_HUMAN
NC score	0.038905 (rank : 36)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	490	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

UB7I4_MOUSE
NC score	0.038013 (rank : 37)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

RP1L1_HUMAN
NC score	0.036868 (rank : 38)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	1072	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

PCLO_MOUSE
NC score	0.036123 (rank : 39)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	2275	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MBB1A_HUMAN
NC score	0.035002 (rank : 40)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	665	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PDZD2_HUMAN
NC score	0.030556 (rank : 41)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	772	Shared Neighborhood Hits	19
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

NIPA_HUMAN
NC score	0.029889 (rank : 42)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

MLL3_MOUSE
NC score	0.029209 (rank : 43)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	1399	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NPAS4_MOUSE
NC score	0.028581 (rank : 44)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	245	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

DOK2_MOUSE
NC score	0.025948 (rank : 45)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	244	Shared Neighborhood Hits	10
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

CU124_HUMAN
NC score	0.024123 (rank : 46)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q96HW9	Gene names	C21orf124
Domain Architecture	No domain graphic available
Description	Protein C21orf124.

PLXB3_MOUSE
NC score	0.022669 (rank : 47)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

YPEL4_HUMAN
NC score	0.020131 (rank : 48)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NS1, Q65Z98	Gene names	YPEL4
Domain Architecture
Description	Protein yippee-like 4.

YETS2_HUMAN
NC score	0.019651 (rank : 49)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

FOXL1_MOUSE
NC score	0.017825 (rank : 50)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

LRSM1_HUMAN
NC score	0.017699 (rank : 51)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	1078	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MADCA_MOUSE
NC score	0.015323 (rank : 52)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q61826, O35530, Q61278, Q64275, Q8R1M6	Gene names	Madcam1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (mMAdCAM-1).

PLXB3_HUMAN
NC score	0.014403 (rank : 53)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

SPEG_HUMAN
NC score	0.014102 (rank : 54)	θ value	0.0563607 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	1762	Shared Neighborhood Hits	31
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

FBX46_MOUSE
NC score	0.013721 (rank : 55)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

GIT2_MOUSE
NC score	0.012235 (rank : 56)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	323	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

CAC1G_HUMAN
NC score	0.012076 (rank : 57)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	587	Shared Neighborhood Hits	23
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

TXLNG_HUMAN
NC score	0.010489 (rank : 58)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	568	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

JADE2_HUMAN
NC score	0.010274 (rank : 59)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

EPHA1_HUMAN
NC score	0.009527 (rank : 60)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	997	Shared Neighborhood Hits	7
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

ANK2_HUMAN
NC score	0.009124 (rank : 61)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	1615	Shared Neighborhood Hits	30
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BEGIN_MOUSE
NC score	0.009043 (rank : 62)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	383	Shared Neighborhood Hits	6
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CNTN1_HUMAN
NC score	0.007241 (rank : 63)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	431	Shared Neighborhood Hits	6
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CO4A2_MOUSE
NC score	0.006751 (rank : 64)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	492	Shared Neighborhood Hits	13
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

TTBK1_HUMAN
NC score	0.006040 (rank : 65)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	1058	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ANKK1_HUMAN
NC score	0.002414 (rank : 66)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	1075	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

TAOK2_MOUSE
NC score	0.002392 (rank : 67)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	1373	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

HXD1_MOUSE
NC score	0.000963 (rank : 68)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).