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Network neighborhood for query Sequence : FBX46_MOUSE

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FBX46_MOUSE
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBX46_HUMAN
θ value	0 (rank : 1)	NC score	0.974744 (rank : 2)
Query Neighborhood Hits	139	Target Neighborhood Hits	68	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

FBX46_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	139	Target Neighborhood Hits	139	Shared Neighborhood Hits	139
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

FBX34_HUMAN
θ value	1.31376e-75 (rank : 3)	NC score	0.867509 (rank : 3)
Query Neighborhood Hits	139	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

FBX34_MOUSE
θ value	8.81223e-72 (rank : 4)	NC score	0.849997 (rank : 4)
Query Neighborhood Hits	139	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

MLL4_HUMAN
θ value	0.0252991 (rank : 5)	NC score	0.058922 (rank : 17)
Query Neighborhood Hits	139	Target Neighborhood Hits	722	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MK07_HUMAN
θ value	0.0431538 (rank : 6)	NC score	0.011175 (rank : 116)
Query Neighborhood Hits	139	Target Neighborhood Hits	1087	Shared Neighborhood Hits	25
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

FBX24_MOUSE
θ value	0.0961366 (rank : 7)	NC score	0.102286 (rank : 6)
Query Neighborhood Hits	139	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D417	Gene names	Fbxo24, Fbx24
Domain Architecture	No domain graphic available
Description	F-box only protein 24.

MILK1_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.046523 (rank : 29)
Query Neighborhood Hits	139	Target Neighborhood Hits	788	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MUCDL_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.050404 (rank : 26)
Query Neighborhood Hits	139	Target Neighborhood Hits	777	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ZN385_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.070255 (rank : 15)
Query Neighborhood Hits	139	Target Neighborhood Hits	614	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

RGS3_HUMAN
θ value	0.163984 (rank : 11)	NC score	0.056227 (rank : 21)
Query Neighborhood Hits	139	Target Neighborhood Hits	1375	Shared Neighborhood Hits	67
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

FBX31_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.110766 (rank : 5)
Query Neighborhood Hits	139	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

FXL12_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.088884 (rank : 7)
Query Neighborhood Hits	139	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

ATX7_MOUSE
θ value	0.365318 (rank : 14)	NC score	0.084385 (rank : 9)
Query Neighborhood Hits	139	Target Neighborhood Hits	328	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

MMP9_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.019945 (rank : 84)
Query Neighborhood Hits	139	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

SETBP_MOUSE
θ value	0.365318 (rank : 16)	NC score	0.053239 (rank : 23)
Query Neighborhood Hits	139	Target Neighborhood Hits	352	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SGIP1_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.071064 (rank : 13)
Query Neighborhood Hits	139	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYNP2_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.032765 (rank : 56)
Query Neighborhood Hits	139	Target Neighborhood Hits	252	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

ZN219_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.010341 (rank : 120)
Query Neighborhood Hits	139	Target Neighborhood Hits	876	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

EPHA3_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.005432 (rank : 134)
Query Neighborhood Hits	139	Target Neighborhood Hits	1005	Shared Neighborhood Hits	10
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

FXL12_MOUSE
θ value	0.47712 (rank : 21)	NC score	0.084677 (rank : 8)
Query Neighborhood Hits	139	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

NCOR2_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.036691 (rank : 49)
Query Neighborhood Hits	139	Target Neighborhood Hits	870	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

MUC1_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.042713 (rank : 36)
Query Neighborhood Hits	139	Target Neighborhood Hits	388	Shared Neighborhood Hits	22
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

ATX7_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.080171 (rank : 11)
Query Neighborhood Hits	139	Target Neighborhood Hits	351	Shared Neighborhood Hits	27
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CK024_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.056868 (rank : 19)
Query Neighborhood Hits	139	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CSKI2_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.020071 (rank : 83)
Query Neighborhood Hits	139	Target Neighborhood Hits	747	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FBX24_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.082601 (rank : 10)
Query Neighborhood Hits	139	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	O75426, Q9H0G1	Gene names	FBXO24, FBX24
Domain Architecture
Description	F-box only protein 24.

IRX3_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.022032 (rank : 81)
Query Neighborhood Hits	139	Target Neighborhood Hits	303	Shared Neighborhood Hits	9
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

ODP2_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.034897 (rank : 50)
Query Neighborhood Hits	139	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

SFPQ_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.039616 (rank : 41)
Query Neighborhood Hits	139	Target Neighborhood Hits	986	Shared Neighborhood Hits	38
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

WASL_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.056237 (rank : 20)
Query Neighborhood Hits	139	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	0.813845 (rank : 32)	NC score	0.052794 (rank : 25)
Query Neighborhood Hits	139	Target Neighborhood Hits	339	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

GATA3_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.019920 (rank : 85)
Query Neighborhood Hits	139	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P23771, Q96J16	Gene names	GATA3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

ITBP2_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.073731 (rank : 12)
Query Neighborhood Hits	139	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKP3	Gene names	ITGB1BP2
Domain Architecture
Description	Integrin beta-1-binding protein 2 (Melusin).

JHD3B_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.018940 (rank : 88)
Query Neighborhood Hits	139	Target Neighborhood Hits	128	Shared Neighborhood Hits	8
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

KCNH3_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.017653 (rank : 91)
Query Neighborhood Hits	139	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

MUC7_HUMAN
θ value	1.06291 (rank : 37)	NC score	0.049991 (rank : 27)
Query Neighborhood Hits	139	Target Neighborhood Hits	538	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NPAS4_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.044259 (rank : 33)
Query Neighborhood Hits	139	Target Neighborhood Hits	245	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

STRC_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.032825 (rank : 55)
Query Neighborhood Hits	139	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

AAK1_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.011910 (rank : 112)
Query Neighborhood Hits	139	Target Neighborhood Hits	1077	Shared Neighborhood Hits	33
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

BSN_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.054991 (rank : 22)
Query Neighborhood Hits	139	Target Neighborhood Hits	2057	Shared Neighborhood Hits	83
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAC1G_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.030974 (rank : 60)
Query Neighborhood Hits	139	Target Neighborhood Hits	587	Shared Neighborhood Hits	41
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

GON4L_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.038318 (rank : 45)
Query Neighborhood Hits	139	Target Neighborhood Hits	555	Shared Neighborhood Hits	17
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

ITBP2_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.070732 (rank : 14)
Query Neighborhood Hits	139	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R000, Q9D161	Gene names	Itgb1bp2
Domain Architecture
Description	Integrin beta-1-binding protein 2 (Melusin).

RASA2_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.043144 (rank : 35)
Query Neighborhood Hits	139	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

XKR7_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.036862 (rank : 48)
Query Neighborhood Hits	139	Target Neighborhood Hits	146	Shared Neighborhood Hits	19
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

YLPM1_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.041251 (rank : 38)
Query Neighborhood Hits	139	Target Neighborhood Hits	505	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZO1_MOUSE
θ value	1.38821 (rank : 48)	NC score	0.016695 (rank : 94)
Query Neighborhood Hits	139	Target Neighborhood Hits	453	Shared Neighborhood Hits	15
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

AIPL1_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.022606 (rank : 80)
Query Neighborhood Hits	139	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

BPAEA_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.009442 (rank : 125)
Query Neighborhood Hits	139	Target Neighborhood Hits	1369	Shared Neighborhood Hits	11
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HCN2_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.029822 (rank : 63)
Query Neighborhood Hits	139	Target Neighborhood Hits	369	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

INSM1_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.015273 (rank : 100)
Query Neighborhood Hits	139	Target Neighborhood Hits	683	Shared Neighborhood Hits	12
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

NPAS4_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.041650 (rank : 37)
Query Neighborhood Hits	139	Target Neighborhood Hits	214	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

OGFR_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.057738 (rank : 18)
Query Neighborhood Hits	139	Target Neighborhood Hits	1582	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PK3CA_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.025381 (rank : 74)
Query Neighborhood Hits	139	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

SNIP_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.041047 (rank : 39)
Query Neighborhood Hits	139	Target Neighborhood Hits	313	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

YYAP1_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.039921 (rank : 40)
Query Neighborhood Hits	139	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H869, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, Q8IXA6, Q8TEW5, Q8TF04, Q96HB6, Q9BQ64, Q9NV84	Gene names	YY1AP1, HCCA2, YY1AP
Domain Architecture	No domain graphic available
Description	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2).

ZBTB4_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.008140 (rank : 129)
Query Neighborhood Hits	139	Target Neighborhood Hits	926	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

BRD4_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.019574 (rank : 87)
Query Neighborhood Hits	139	Target Neighborhood Hits	845	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CSF1_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.044306 (rank : 32)
Query Neighborhood Hits	139	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CSKI1_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.021940 (rank : 82)
Query Neighborhood Hits	139	Target Neighborhood Hits	1031	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

GSCR1_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.039459 (rank : 42)
Query Neighborhood Hits	139	Target Neighborhood Hits	674	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PK3CA_MOUSE
θ value	2.36792 (rank : 63)	NC score	0.025444 (rank : 73)
Query Neighborhood Hits	139	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

RASA3_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.031525 (rank : 58)
Query Neighborhood Hits	139	Target Neighborhood Hits	166	Shared Neighborhood Hits	6
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

SCMH1_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.027744 (rank : 70)
Query Neighborhood Hits	139	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q96GD3, Q5VT76, Q6IAJ4, Q8WU48, Q9UKM5, Q9UKM6	Gene names	SCMH1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

SCMH1_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.028411 (rank : 68)
Query Neighborhood Hits	139	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

SGIP1_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.061087 (rank : 16)
Query Neighborhood Hits	139	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYNJ2_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.017898 (rank : 90)
Query Neighborhood Hits	139	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

FBXL7_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.032741 (rank : 57)
Query Neighborhood Hits	139	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

GCYB1_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.011422 (rank : 114)
Query Neighborhood Hits	139	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q02153, Q86WY5	Gene names	GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit) (GCS-beta-3).

HXD3_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.013303 (rank : 107)
Query Neighborhood Hits	139	Target Neighborhood Hits	435	Shared Neighborhood Hits	11
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

WASF1_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.027414 (rank : 72)
Query Neighborhood Hits	139	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.027480 (rank : 71)
Query Neighborhood Hits	139	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WWP2_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.008326 (rank : 128)
Query Neighborhood Hits	139	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

XKR7_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.028129 (rank : 69)
Query Neighborhood Hits	139	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q5GH72, Q9NUG5	Gene names	XKR7, C20orf159, XRG7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

ZN598_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.024659 (rank : 76)
Query Neighborhood Hits	139	Target Neighborhood Hits	339	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ABI2_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.012253 (rank : 111)
Query Neighborhood Hits	139	Target Neighborhood Hits	350	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

AMOT_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.016642 (rank : 95)
Query Neighborhood Hits	139	Target Neighborhood Hits	712	Shared Neighborhood Hits	27
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

B3A3_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.011497 (rank : 113)
Query Neighborhood Hits	139	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

BAG3_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.029385 (rank : 65)
Query Neighborhood Hits	139	Target Neighborhood Hits	314	Shared Neighborhood Hits	30
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

EP300_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.024385 (rank : 77)
Query Neighborhood Hits	139	Target Neighborhood Hits	821	Shared Neighborhood Hits	34
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MNT_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.032977 (rank : 54)
Query Neighborhood Hits	139	Target Neighborhood Hits	496	Shared Neighborhood Hits	39
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MUC2_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.023922 (rank : 79)
Query Neighborhood Hits	139	Target Neighborhood Hits	906	Shared Neighborhood Hits	38
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PAK4_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.002998 (rank : 138)
Query Neighborhood Hits	139	Target Neighborhood Hits	924	Shared Neighborhood Hits	16
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

RASA2_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.030978 (rank : 59)
Query Neighborhood Hits	139	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RON_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.004118 (rank : 136)
Query Neighborhood Hits	139	Target Neighborhood Hits	836	Shared Neighborhood Hits	7
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

SNIP_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.037244 (rank : 46)
Query Neighborhood Hits	139	Target Neighborhood Hits	319	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

TAU_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.045193 (rank : 30)
Query Neighborhood Hits	139	Target Neighborhood Hits	448	Shared Neighborhood Hits	30
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

AP180_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.018647 (rank : 89)
Query Neighborhood Hits	139	Target Neighborhood Hits	194	Shared Neighborhood Hits	16
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

ATX2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.024192 (rank : 78)
Query Neighborhood Hits	139	Target Neighborhood Hits	375	Shared Neighborhood Hits	20
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

BARH2_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.008061 (rank : 130)
Query Neighborhood Hits	139	Target Neighborhood Hits	397	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VIB5, Q66L43	Gene names	Barhl2, Barh1, Mbh1
Domain Architecture	No domain graphic available
Description	BarH-like 2 homeobox protein (Bar-class homeodomain protein MBH1) (Homeobox protein B-H1).

BRSK1_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.002544 (rank : 139)
Query Neighborhood Hits	139	Target Neighborhood Hits	942	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

BSN_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.037013 (rank : 47)
Query Neighborhood Hits	139	Target Neighborhood Hits	1537	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

GP1BA_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.009388 (rank : 126)
Query Neighborhood Hits	139	Target Neighborhood Hits	407	Shared Neighborhood Hits	16
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

IF4B_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.028539 (rank : 67)
Query Neighborhood Hits	139	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

K2C1B_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.002435 (rank : 140)
Query Neighborhood Hits	139	Target Neighborhood Hits	503	Shared Neighborhood Hits	4
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

MLL2_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.030306 (rank : 61)
Query Neighborhood Hits	139	Target Neighborhood Hits	1788	Shared Neighborhood Hits	64
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PRR12_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.039135 (rank : 43)
Query Neighborhood Hits	139	Target Neighborhood Hits	460	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SF3B1_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.034056 (rank : 52)
Query Neighborhood Hits	139	Target Neighborhood Hits	341	Shared Neighborhood Hits	23
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.034012 (rank : 53)
Query Neighborhood Hits	139	Target Neighborhood Hits	352	Shared Neighborhood Hits	23
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SPAG5_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.009584 (rank : 124)
Query Neighborhood Hits	139	Target Neighborhood Hits	625	Shared Neighborhood Hits	8
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

WASIP_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.034169 (rank : 51)
Query Neighborhood Hits	139	Target Neighborhood Hits	458	Shared Neighborhood Hits	26
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ADAM8_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.003811 (rank : 137)
Query Neighborhood Hits	139	Target Neighborhood Hits	326	Shared Neighborhood Hits	7
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ATX2_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.029610 (rank : 64)
Query Neighborhood Hits	139	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BAT2_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.043159 (rank : 34)
Query Neighborhood Hits	139	Target Neighborhood Hits	947	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BMAL1_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.014077 (rank : 105)
Query Neighborhood Hits	139	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.014112 (rank : 104)
Query Neighborhood Hits	139	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

BPA1_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.008362 (rank : 127)
Query Neighborhood Hits	139	Target Neighborhood Hits	1477	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CC019_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.025004 (rank : 75)
Query Neighborhood Hits	139	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PII3, Q96CS5	Gene names	C3orf19
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf19.

DPOLL_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.012797 (rank : 109)
Query Neighborhood Hits	139	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

HXA3_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.010901 (rank : 118)
Query Neighborhood Hits	139	Target Neighborhood Hits	558	Shared Neighborhood Hits	25
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

KCNC3_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.007946 (rank : 131)
Query Neighborhood Hits	139	Target Neighborhood Hits	256	Shared Neighborhood Hits	17
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

NACAM_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.049355 (rank : 28)
Query Neighborhood Hits	139	Target Neighborhood Hits	1866	Shared Neighborhood Hits	87
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RD23B_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.017574 (rank : 92)
Query Neighborhood Hits	139	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RIN3_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.016214 (rank : 97)
Query Neighborhood Hits	139	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SET1A_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.038640 (rank : 44)
Query Neighborhood Hits	139	Target Neighborhood Hits	690	Shared Neighborhood Hits	23
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SFPQ_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.028674 (rank : 66)
Query Neighborhood Hits	139	Target Neighborhood Hits	958	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SPRE3_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.013721 (rank : 106)
Query Neighborhood Hits	139	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SRRM2_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.030183 (rank : 62)
Query Neighborhood Hits	139	Target Neighborhood Hits	1470	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STAB2_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.005962 (rank : 133)
Query Neighborhood Hits	139	Target Neighborhood Hits	534	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TJAP1_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.010975 (rank : 117)
Query Neighborhood Hits	139	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

ZN687_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.009798 (rank : 123)
Query Neighborhood Hits	139	Target Neighborhood Hits	913	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AMBN_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.014750 (rank : 102)
Query Neighborhood Hits	139	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

BARH2_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.006536 (rank : 132)
Query Neighborhood Hits	139	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

BPL1_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.013126 (rank : 108)
Query Neighborhood Hits	139	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q920N2	Gene names	Hlcs
Domain Architecture
Description	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin-- [methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin-- [acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)].

CK024_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.045140 (rank : 31)
Query Neighborhood Hits	139	Target Neighborhood Hits	408	Shared Neighborhood Hits	36
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

DAG1_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.016101 (rank : 98)
Query Neighborhood Hits	139	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

EMSY_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.016255 (rank : 96)
Query Neighborhood Hits	139	Target Neighborhood Hits	296	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

EP400_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.012692 (rank : 110)
Query Neighborhood Hits	139	Target Neighborhood Hits	556	Shared Neighborhood Hits	31
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

KMO_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.019639 (rank : 86)
Query Neighborhood Hits	139	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O15229, Q5SY07, Q5SY08, Q5SY09	Gene names	KMO
Domain Architecture	No domain graphic available
Description	Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase).

LAT_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.016988 (rank : 93)
Query Neighborhood Hits	139	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	O43561, O43919	Gene names	LAT
Domain Architecture	No domain graphic available
Description	Linker for activation of T-cells family member 1 (36 kDa phospho- tyrosine adapter protein) (pp36) (p36-38).

MA1B1_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.015142 (rank : 101)
Query Neighborhood Hits	139	Target Neighborhood Hits	125	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MICA1_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.014626 (rank : 103)
Query Neighborhood Hits	139	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

NOTC2_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.004530 (rank : 135)
Query Neighborhood Hits	139	Target Neighborhood Hits	1113	Shared Neighborhood Hits	37
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PACE1_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.010360 (rank : 119)
Query Neighborhood Hits	139	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PCX3_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.015875 (rank : 99)
Query Neighborhood Hits	139	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

REPS2_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.011233 (rank : 115)
Query Neighborhood Hits	139	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

UBP53_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.010097 (rank : 121)
Query Neighborhood Hits	139	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UHRF1_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.009928 (rank : 122)
Query Neighborhood Hits	139	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

MUC1_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.052815 (rank : 24)
Query Neighborhood Hits	139	Target Neighborhood Hits	975	Shared Neighborhood Hits	67
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

Hits sorted by NC score

FBX46_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	139	Target Neighborhood Hits	139	Shared Neighborhood Hits	139
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

FBX46_HUMAN
NC score	0.974744 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	139	Target Neighborhood Hits	68	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

FBX34_HUMAN
NC score	0.867509 (rank : 3)	θ value	1.31376e-75 (rank : 3)
Query Neighborhood Hits	139	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

FBX34_MOUSE
NC score	0.849997 (rank : 4)	θ value	8.81223e-72 (rank : 4)
Query Neighborhood Hits	139	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

FBX31_HUMAN
NC score	0.110766 (rank : 5)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	139	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

FBX24_MOUSE
NC score	0.102286 (rank : 6)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	139	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D417	Gene names	Fbxo24, Fbx24
Domain Architecture	No domain graphic available
Description	F-box only protein 24.

FXL12_HUMAN
NC score	0.088884 (rank : 7)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	139	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL12_MOUSE
NC score	0.084677 (rank : 8)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	139	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

ATX7_MOUSE
NC score	0.084385 (rank : 9)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	139	Target Neighborhood Hits	328	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

FBX24_HUMAN
NC score	0.082601 (rank : 10)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	139	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	O75426, Q9H0G1	Gene names	FBXO24, FBX24
Domain Architecture
Description	F-box only protein 24.

ATX7_HUMAN
NC score	0.080171 (rank : 11)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	139	Target Neighborhood Hits	351	Shared Neighborhood Hits	27
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

ITBP2_HUMAN
NC score	0.073731 (rank : 12)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	139	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKP3	Gene names	ITGB1BP2
Domain Architecture
Description	Integrin beta-1-binding protein 2 (Melusin).

SGIP1_MOUSE
NC score	0.071064 (rank : 13)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	139	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

ITBP2_MOUSE
NC score	0.070732 (rank : 14)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	139	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R000, Q9D161	Gene names	Itgb1bp2
Domain Architecture
Description	Integrin beta-1-binding protein 2 (Melusin).

ZN385_HUMAN
NC score	0.070255 (rank : 15)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	139	Target Neighborhood Hits	614	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SGIP1_HUMAN
NC score	0.061087 (rank : 16)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	139	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

MLL4_HUMAN
NC score	0.058922 (rank : 17)	θ value	0.0252991 (rank : 5)
Query Neighborhood Hits	139	Target Neighborhood Hits	722	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

OGFR_HUMAN
NC score	0.057738 (rank : 18)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	139	Target Neighborhood Hits	1582	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CK024_MOUSE
NC score	0.056868 (rank : 19)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	139	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

WASL_HUMAN
NC score	0.056237 (rank : 20)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	139	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RGS3_HUMAN
NC score	0.056227 (rank : 21)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	139	Target Neighborhood Hits	1375	Shared Neighborhood Hits	67
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

BSN_MOUSE
NC score	0.054991 (rank : 22)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	139	Target Neighborhood Hits	2057	Shared Neighborhood Hits	83
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SETBP_MOUSE
NC score	0.053239 (rank : 23)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	139	Target Neighborhood Hits	352	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

MUC1_HUMAN
NC score	0.052815 (rank : 24)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	139	Target Neighborhood Hits	975	Shared Neighborhood Hits	67
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

WASL_MOUSE
NC score	0.052794 (rank : 25)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	139	Target Neighborhood Hits	339	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MUCDL_HUMAN
NC score	0.050404 (rank : 26)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	139	Target Neighborhood Hits	777	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUC7_HUMAN
NC score	0.049991 (rank : 27)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	139	Target Neighborhood Hits	538	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NACAM_MOUSE
NC score	0.049355 (rank : 28)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	139	Target Neighborhood Hits	1866	Shared Neighborhood Hits	87
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MILK1_MOUSE
NC score	0.046523 (rank : 29)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	139	Target Neighborhood Hits	788	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TAU_HUMAN
NC score	0.045193 (rank : 30)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	139	Target Neighborhood Hits	448	Shared Neighborhood Hits	30
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CK024_HUMAN
NC score	0.045140 (rank : 31)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	139	Target Neighborhood Hits	408	Shared Neighborhood Hits	36
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CSF1_HUMAN
NC score	0.044306 (rank : 32)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	139	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

NPAS4_MOUSE
NC score	0.044259 (rank : 33)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	139	Target Neighborhood Hits	245	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

BAT2_MOUSE
NC score	0.043159 (rank : 34)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	139	Target Neighborhood Hits	947	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RASA2_MOUSE
NC score	0.043144 (rank : 35)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	139	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

MUC1_MOUSE
NC score	0.042713 (rank : 36)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	139	Target Neighborhood Hits	388	Shared Neighborhood Hits	22
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NPAS4_HUMAN
NC score	0.041650 (rank : 37)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	139	Target Neighborhood Hits	214	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

YLPM1_MOUSE
NC score	0.041251 (rank : 38)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	139	Target Neighborhood Hits	505	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

SNIP_HUMAN
NC score	0.041047 (rank : 39)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	139	Target Neighborhood Hits	313	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

YYAP1_HUMAN
NC score	0.039921 (rank : 40)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	139	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H869, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, Q8IXA6, Q8TEW5, Q8TF04, Q96HB6, Q9BQ64, Q9NV84	Gene names	YY1AP1, HCCA2, YY1AP
Domain Architecture	No domain graphic available
Description	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2).

SFPQ_HUMAN
NC score	0.039616 (rank : 41)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	139	Target Neighborhood Hits	986	Shared Neighborhood Hits	38
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

GSCR1_HUMAN
NC score	0.039459 (rank : 42)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	139	Target Neighborhood Hits	674	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PRR12_HUMAN
NC score	0.039135 (rank : 43)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	139	Target Neighborhood Hits	460	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SET1A_HUMAN
NC score	0.038640 (rank : 44)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	139	Target Neighborhood Hits	690	Shared Neighborhood Hits	23
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

GON4L_HUMAN
NC score	0.038318 (rank : 45)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	139	Target Neighborhood Hits	555	Shared Neighborhood Hits	17
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SNIP_MOUSE
NC score	0.037244 (rank : 46)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	139	Target Neighborhood Hits	319	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

BSN_HUMAN
NC score	0.037013 (rank : 47)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	139	Target Neighborhood Hits	1537	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

XKR7_MOUSE
NC score	0.036862 (rank : 48)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	139	Target Neighborhood Hits	146	Shared Neighborhood Hits	19
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

NCOR2_HUMAN
NC score	0.036691 (rank : 49)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	139	Target Neighborhood Hits	870	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

ODP2_HUMAN
NC score	0.034897 (rank : 50)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	139	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

WASIP_HUMAN
NC score	0.034169 (rank : 51)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	139	Target Neighborhood Hits	458	Shared Neighborhood Hits	26
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SF3B1_HUMAN
NC score	0.034056 (rank : 52)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	139	Target Neighborhood Hits	341	Shared Neighborhood Hits	23
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.034012 (rank : 53)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	139	Target Neighborhood Hits	352	Shared Neighborhood Hits	23
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

MNT_HUMAN
NC score	0.032977 (rank : 54)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	139	Target Neighborhood Hits	496	Shared Neighborhood Hits	39
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

STRC_MOUSE
NC score	0.032825 (rank : 55)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	139	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

SYNP2_MOUSE
NC score	0.032765 (rank : 56)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	139	Target Neighborhood Hits	252	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

FBXL7_HUMAN
NC score	0.032741 (rank : 57)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	139	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

RASA3_HUMAN
NC score	0.031525 (rank : 58)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	139	Target Neighborhood Hits	166	Shared Neighborhood Hits	6
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA2_HUMAN
NC score	0.030978 (rank : 59)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	139	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

CAC1G_HUMAN
NC score	0.030974 (rank : 60)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	139	Target Neighborhood Hits	587	Shared Neighborhood Hits	41
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

MLL2_HUMAN
NC score	0.030306 (rank : 61)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	139	Target Neighborhood Hits	1788	Shared Neighborhood Hits	64
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SRRM2_MOUSE
NC score	0.030183 (rank : 62)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	139	Target Neighborhood Hits	1470	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

HCN2_HUMAN
NC score	0.029822 (rank : 63)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	139	Target Neighborhood Hits	369	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

ATX2_MOUSE
NC score	0.029610 (rank : 64)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	139	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BAG3_HUMAN
NC score	0.029385 (rank : 65)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	139	Target Neighborhood Hits	314	Shared Neighborhood Hits	30
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

SFPQ_MOUSE
NC score	0.028674 (rank : 66)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	139	Target Neighborhood Hits	958	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

IF4B_HUMAN
NC score	0.028539 (rank : 67)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	139	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

SCMH1_MOUSE
NC score	0.028411 (rank : 68)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	139	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

XKR7_HUMAN
NC score	0.028129 (rank : 69)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	139	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q5GH72, Q9NUG5	Gene names	XKR7, C20orf159, XRG7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

SCMH1_HUMAN
NC score	0.027744 (rank : 70)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	139	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q96GD3, Q5VT76, Q6IAJ4, Q8WU48, Q9UKM5, Q9UKM6	Gene names	SCMH1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

WASF1_MOUSE
NC score	0.027480 (rank : 71)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	139	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF1_HUMAN
NC score	0.027414 (rank : 72)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	139	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

PK3CA_MOUSE
NC score	0.025444 (rank : 73)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	139	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_HUMAN
NC score	0.025381 (rank : 74)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	139	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

CC019_HUMAN
NC score	0.025004 (rank : 75)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	139	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PII3, Q96CS5	Gene names	C3orf19
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf19.

ZN598_HUMAN
NC score	0.024659 (rank : 76)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	139	Target Neighborhood Hits	339	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

EP300_HUMAN
NC score	0.024385 (rank : 77)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	139	Target Neighborhood Hits	821	Shared Neighborhood Hits	34
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ATX2_HUMAN
NC score	0.024192 (rank : 78)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	139	Target Neighborhood Hits	375	Shared Neighborhood Hits	20
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

MUC2_HUMAN
NC score	0.023922 (rank : 79)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	139	Target Neighborhood Hits	906	Shared Neighborhood Hits	38
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

AIPL1_HUMAN
NC score	0.022606 (rank : 80)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	139	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

IRX3_MOUSE
NC score	0.022032 (rank : 81)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	139	Target Neighborhood Hits	303	Shared Neighborhood Hits	9
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

CSKI1_MOUSE
NC score	0.021940 (rank : 82)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	139	Target Neighborhood Hits	1031	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
NC score	0.020071 (rank : 83)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	139	Target Neighborhood Hits	747	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MMP9_HUMAN
NC score	0.019945 (rank : 84)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	139	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

GATA3_HUMAN
NC score	0.019920 (rank : 85)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	139	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P23771, Q96J16	Gene names	GATA3
Domain Architecture
Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3).

KMO_HUMAN
NC score	0.019639 (rank : 86)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	139	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O15229, Q5SY07, Q5SY08, Q5SY09	Gene names	KMO
Domain Architecture	No domain graphic available
Description	Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase).

BRD4_MOUSE
NC score	0.019574 (rank : 87)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	139	Target Neighborhood Hits	845	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

JHD3B_HUMAN
NC score	0.018940 (rank : 88)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	139	Target Neighborhood Hits	128	Shared Neighborhood Hits	8
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

AP180_MOUSE
NC score	0.018647 (rank : 89)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	139	Target Neighborhood Hits	194	Shared Neighborhood Hits	16
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

SYNJ2_HUMAN
NC score	0.017898 (rank : 90)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	139	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

KCNH3_MOUSE
NC score	0.017653 (rank : 91)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	139	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

RD23B_MOUSE
NC score	0.017574 (rank : 92)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	139	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

LAT_HUMAN
NC score	0.016988 (rank : 93)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	139	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	O43561, O43919	Gene names	LAT
Domain Architecture	No domain graphic available
Description	Linker for activation of T-cells family member 1 (36 kDa phospho- tyrosine adapter protein) (pp36) (p36-38).

ZO1_MOUSE
NC score	0.016695 (rank : 94)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	139	Target Neighborhood Hits	453	Shared Neighborhood Hits	15
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

AMOT_HUMAN
NC score	0.016642 (rank : 95)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	139	Target Neighborhood Hits	712	Shared Neighborhood Hits	27
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

EMSY_HUMAN
NC score	0.016255 (rank : 96)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	139	Target Neighborhood Hits	296	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

RIN3_HUMAN
NC score	0.016214 (rank : 97)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	139	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

DAG1_MOUSE
NC score	0.016101 (rank : 98)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	139	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

PCX3_MOUSE
NC score	0.015875 (rank : 99)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	139	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

INSM1_HUMAN
NC score	0.015273 (rank : 100)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	139	Target Neighborhood Hits	683	Shared Neighborhood Hits	12
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

MA1B1_HUMAN
NC score	0.015142 (rank : 101)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	139	Target Neighborhood Hits	125	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

AMBN_HUMAN
NC score	0.014750 (rank : 102)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	139	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

MICA1_HUMAN
NC score	0.014626 (rank : 103)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	139	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

BMAL1_MOUSE
NC score	0.014112 (rank : 104)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	139	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

BMAL1_HUMAN
NC score	0.014077 (rank : 105)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	139	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

SPRE3_HUMAN
NC score	0.013721 (rank : 106)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	139	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

HXD3_MOUSE
NC score	0.013303 (rank : 107)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	139	Target Neighborhood Hits	435	Shared Neighborhood Hits	11
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

BPL1_MOUSE
NC score	0.013126 (rank : 108)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	139	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q920N2	Gene names	Hlcs
Domain Architecture
Description	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin-- [methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin-- [acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)].

DPOLL_HUMAN
NC score	0.012797 (rank : 109)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	139	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

EP400_HUMAN
NC score	0.012692 (rank : 110)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	139	Target Neighborhood Hits	556	Shared Neighborhood Hits	31
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ABI2_HUMAN
NC score	0.012253 (rank : 111)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	139	Target Neighborhood Hits	350	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

AAK1_HUMAN
NC score	0.011910 (rank : 112)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	139	Target Neighborhood Hits	1077	Shared Neighborhood Hits	33
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

B3A3_MOUSE
NC score	0.011497 (rank : 113)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	139	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

GCYB1_HUMAN
NC score	0.011422 (rank : 114)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	139	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q02153, Q86WY5	Gene names	GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit) (GCS-beta-3).

REPS2_MOUSE
NC score	0.011233 (rank : 115)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	139	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

MK07_HUMAN
NC score	0.011175 (rank : 116)	θ value	0.0431538 (rank : 6)
Query Neighborhood Hits	139	Target Neighborhood Hits	1087	Shared Neighborhood Hits	25
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

TJAP1_MOUSE
NC score	0.010975 (rank : 117)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	139	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

HXA3_MOUSE
NC score	0.010901 (rank : 118)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	139	Target Neighborhood Hits	558	Shared Neighborhood Hits	25
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

PACE1_MOUSE
NC score	0.010360 (rank : 119)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	139	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

ZN219_HUMAN
NC score	0.010341 (rank : 120)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	139	Target Neighborhood Hits	876	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

UBP53_HUMAN
NC score	0.010097 (rank : 121)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	139	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UHRF1_MOUSE
NC score	0.009928 (rank : 122)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	139	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

ZN687_MOUSE
NC score	0.009798 (rank : 123)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	139	Target Neighborhood Hits	913	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

SPAG5_HUMAN
NC score	0.009584 (rank : 124)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	139	Target Neighborhood Hits	625	Shared Neighborhood Hits	8
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

BPAEA_HUMAN
NC score	0.009442 (rank : 125)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	139	Target Neighborhood Hits	1369	Shared Neighborhood Hits	11
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GP1BA_HUMAN
NC score	0.009388 (rank : 126)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	139	Target Neighborhood Hits	407	Shared Neighborhood Hits	16
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

BPA1_MOUSE
NC score	0.008362 (rank : 127)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	139	Target Neighborhood Hits	1477	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

WWP2_MOUSE
NC score	0.008326 (rank : 128)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	139	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

ZBTB4_HUMAN
NC score	0.008140 (rank : 129)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	139	Target Neighborhood Hits	926	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

BARH2_MOUSE
NC score	0.008061 (rank : 130)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	139	Target Neighborhood Hits	397	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VIB5, Q66L43	Gene names	Barhl2, Barh1, Mbh1
Domain Architecture	No domain graphic available
Description	BarH-like 2 homeobox protein (Bar-class homeodomain protein MBH1) (Homeobox protein B-H1).

KCNC3_HUMAN
NC score	0.007946 (rank : 131)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	139	Target Neighborhood Hits	256	Shared Neighborhood Hits	17
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

BARH2_HUMAN
NC score	0.006536 (rank : 132)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	139	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

STAB2_HUMAN
NC score	0.005962 (rank : 133)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	139	Target Neighborhood Hits	534	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

EPHA3_HUMAN
NC score	0.005432 (rank : 134)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	139	Target Neighborhood Hits	1005	Shared Neighborhood Hits	10
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

NOTC2_HUMAN
NC score	0.004530 (rank : 135)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	139	Target Neighborhood Hits	1113	Shared Neighborhood Hits	37
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RON_MOUSE
NC score	0.004118 (rank : 136)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	139	Target Neighborhood Hits	836	Shared Neighborhood Hits	7
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ADAM8_MOUSE
NC score	0.003811 (rank : 137)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	139	Target Neighborhood Hits	326	Shared Neighborhood Hits	7
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

PAK4_HUMAN
NC score	0.002998 (rank : 138)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	139	Target Neighborhood Hits	924	Shared Neighborhood Hits	16
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

BRSK1_HUMAN
NC score	0.002544 (rank : 139)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	139	Target Neighborhood Hits	942	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

K2C1B_MOUSE
NC score	0.002435 (rank : 140)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	139	Target Neighborhood Hits	503	Shared Neighborhood Hits	4
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).