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Network neighborhood for query Sequence : KCNH3_MOUSE

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KCNH3_MOUSE
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNH3_HUMAN
θ value	0 (rank : 1)	NC score	0.994671 (rank : 2)
Query Neighborhood Hits	133	Target Neighborhood Hits	148	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	133	Target Neighborhood Hits	133	Shared Neighborhood Hits	133
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH4_HUMAN
θ value	0 (rank : 3)	NC score	0.980755 (rank : 4)
Query Neighborhood Hits	133	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH8_HUMAN
θ value	0 (rank : 4)	NC score	0.984758 (rank : 3)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	53
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH6_HUMAN
θ value	5.23575e-141 (rank : 5)	NC score	0.961308 (rank : 9)
Query Neighborhood Hits	133	Target Neighborhood Hits	222	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH1_MOUSE
θ value	4.01817e-133 (rank : 6)	NC score	0.961886 (rank : 5)
Query Neighborhood Hits	133	Target Neighborhood Hits	94	Shared Neighborhood Hits	49
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH5_MOUSE
θ value	5.24793e-133 (rank : 7)	NC score	0.961543 (rank : 7)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH1_HUMAN
θ value	8.9516e-133 (rank : 8)	NC score	0.961757 (rank : 6)
Query Neighborhood Hits	133	Target Neighborhood Hits	98	Shared Neighborhood Hits	50
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH5_HUMAN
θ value	8.9516e-133 (rank : 9)	NC score	0.961425 (rank : 8)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH2_MOUSE
θ value	1.75513e-112 (rank : 10)	NC score	0.951348 (rank : 11)
Query Neighborhood Hits	133	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH2_HUMAN
θ value	2.29227e-112 (rank : 11)	NC score	0.951447 (rank : 10)
Query Neighborhood Hits	133	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH7_MOUSE
θ value	2.22025e-107 (rank : 12)	NC score	0.950083 (rank : 12)
Query Neighborhood Hits	133	Target Neighborhood Hits	98	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
θ value	2.71407e-105 (rank : 13)	NC score	0.948987 (rank : 13)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

CNGA1_MOUSE
θ value	1.37539e-32 (rank : 14)	NC score	0.793841 (rank : 17)
Query Neighborhood Hits	133	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	6.82597e-32 (rank : 15)	NC score	0.797120 (rank : 16)
Query Neighborhood Hits	133	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
θ value	8.91499e-32 (rank : 16)	NC score	0.806599 (rank : 14)
Query Neighborhood Hits	133	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
θ value	1.16434e-31 (rank : 17)	NC score	0.797803 (rank : 15)
Query Neighborhood Hits	133	Target Neighborhood Hits	149	Shared Neighborhood Hits	33
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN4_HUMAN
θ value	8.3442e-30 (rank : 18)	NC score	0.764495 (rank : 24)
Query Neighborhood Hits	133	Target Neighborhood Hits	303	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN1_HUMAN
θ value	2.42779e-29 (rank : 19)	NC score	0.781208 (rank : 19)
Query Neighborhood Hits	133	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	2.42779e-29 (rank : 20)	NC score	0.777258 (rank : 20)
Query Neighborhood Hits	133	Target Neighborhood Hits	172	Shared Neighborhood Hits	34
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

CNGA3_HUMAN
θ value	3.17079e-29 (rank : 21)	NC score	0.793261 (rank : 18)
Query Neighborhood Hits	133	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN2_HUMAN
θ value	4.14116e-29 (rank : 22)	NC score	0.759634 (rank : 26)
Query Neighborhood Hits	133	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN4_MOUSE
θ value	5.40856e-29 (rank : 23)	NC score	0.762826 (rank : 25)
Query Neighborhood Hits	133	Target Neighborhood Hits	284	Shared Neighborhood Hits	59
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_MOUSE
θ value	2.68423e-28 (rank : 24)	NC score	0.766645 (rank : 23)
Query Neighborhood Hits	133	Target Neighborhood Hits	278	Shared Neighborhood Hits	54
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN3_MOUSE
θ value	1.47289e-26 (rank : 25)	NC score	0.775849 (rank : 21)
Query Neighborhood Hits	133	Target Neighborhood Hits	112	Shared Neighborhood Hits	38
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
θ value	3.28125e-26 (rank : 26)	NC score	0.775828 (rank : 22)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

CNGB1_HUMAN
θ value	1.63225e-17 (rank : 27)	NC score	0.714034 (rank : 29)
Query Neighborhood Hits	133	Target Neighborhood Hits	222	Shared Neighborhood Hits	38
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
θ value	4.91457e-14 (rank : 28)	NC score	0.715687 (rank : 28)
Query Neighborhood Hits	133	Target Neighborhood Hits	206	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_MOUSE
θ value	5.43371e-13 (rank : 29)	NC score	0.726821 (rank : 27)
Query Neighborhood Hits	133	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

KCNKH_HUMAN
θ value	0.00175202 (rank : 30)	NC score	0.250350 (rank : 30)
Query Neighborhood Hits	133	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

FA47B_HUMAN
θ value	0.00298849 (rank : 31)	NC score	0.038091 (rank : 67)
Query Neighborhood Hits	133	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

KCNK3_MOUSE
θ value	0.00869519 (rank : 32)	NC score	0.179610 (rank : 35)
Query Neighborhood Hits	133	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK3_HUMAN
θ value	0.0113563 (rank : 33)	NC score	0.182977 (rank : 33)
Query Neighborhood Hits	133	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNKF_HUMAN
θ value	0.0193708 (rank : 34)	NC score	0.189924 (rank : 31)
Query Neighborhood Hits	133	Target Neighborhood Hits	87	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

PSL1_HUMAN
θ value	0.0252991 (rank : 35)	NC score	0.051520 (rank : 60)
Query Neighborhood Hits	133	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SAPS1_HUMAN
θ value	0.0252991 (rank : 36)	NC score	0.038772 (rank : 66)
Query Neighborhood Hits	133	Target Neighborhood Hits	704	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MAGE1_HUMAN
θ value	0.0330416 (rank : 37)	NC score	0.035458 (rank : 70)
Query Neighborhood Hits	133	Target Neighborhood Hits	1389	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

KCNK4_HUMAN
θ value	0.0431538 (rank : 38)	NC score	0.168936 (rank : 38)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNKA_HUMAN
θ value	0.0431538 (rank : 39)	NC score	0.175337 (rank : 36)
Query Neighborhood Hits	133	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

MINP1_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.049635 (rank : 61)
Query Neighborhood Hits	133	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNW1, O95172, O95286, Q59EJ2, Q9UGA3	Gene names	MINPP1, MIPP
Domain Architecture	No domain graphic available
Description	Multiple inositol polyphosphate phosphatase 1 precursor (EC 3.1.3.62) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase).

KCNK2_HUMAN
θ value	0.0563607 (rank : 41)	NC score	0.183384 (rank : 32)
Query Neighborhood Hits	133	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	0.0563607 (rank : 42)	NC score	0.182717 (rank : 34)
Query Neighborhood Hits	133	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KGP1A_HUMAN
θ value	0.0736092 (rank : 43)	NC score	0.041923 (rank : 64)
Query Neighborhood Hits	133	Target Neighborhood Hits	901	Shared Neighborhood Hits	35
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.0736092 (rank : 44)	NC score	0.041989 (rank : 63)
Query Neighborhood Hits	133	Target Neighborhood Hits	921	Shared Neighborhood Hits	35
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

MTA2_MOUSE
θ value	0.0961366 (rank : 45)	NC score	0.021233 (rank : 88)
Query Neighborhood Hits	133	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R190, Q3TVT8	Gene names	Mta2, Mta1l1
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1).

BICD1_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.015786 (rank : 102)
Query Neighborhood Hits	133	Target Neighborhood Hits	844	Shared Neighborhood Hits	11
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

KGP1B_MOUSE
θ value	0.163984 (rank : 47)	NC score	0.041510 (rank : 65)
Query Neighborhood Hits	133	Target Neighborhood Hits	922	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KCNK9_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.153868 (rank : 42)
Query Neighborhood Hits	133	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	0.279714 (rank : 49)	NC score	0.154050 (rank : 40)
Query Neighborhood Hits	133	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

FOXN1_MOUSE
θ value	0.47712 (rank : 50)	NC score	0.013901 (rank : 106)
Query Neighborhood Hits	133	Target Neighborhood Hits	300	Shared Neighborhood Hits	12
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

KCNK6_HUMAN
θ value	0.47712 (rank : 51)	NC score	0.172856 (rank : 37)
Query Neighborhood Hits	133	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

PCLO_MOUSE
θ value	0.47712 (rank : 52)	NC score	0.021544 (rank : 87)
Query Neighborhood Hits	133	Target Neighborhood Hits	2275	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

KCNK5_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.126564 (rank : 45)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

SEM6C_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.011659 (rank : 114)
Query Neighborhood Hits	133	Target Neighborhood Hits	352	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

BICD1_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.012342 (rank : 110)
Query Neighborhood Hits	133	Target Neighborhood Hits	837	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

DCBD1_MOUSE
θ value	1.06291 (rank : 56)	NC score	0.012200 (rank : 111)
Query Neighborhood Hits	133	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DEPP_MOUSE
θ value	1.06291 (rank : 57)	NC score	0.025240 (rank : 81)
Query Neighborhood Hits	133	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2F3, Q8BU66	Gene names	Depp, Fseg
Domain Architecture	No domain graphic available
Description	Protein DEPP (Fat-specific expressed gene protein).

FBX46_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.017653 (rank : 94)
Query Neighborhood Hits	133	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

KCNK4_MOUSE
θ value	1.06291 (rank : 59)	NC score	0.154005 (rank : 41)
Query Neighborhood Hits	133	Target Neighborhood Hits	118	Shared Neighborhood Hits	36
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNKG_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.159805 (rank : 39)
Query Neighborhood Hits	133	Target Neighborhood Hits	90	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

MUC5B_HUMAN
θ value	1.06291 (rank : 61)	NC score	0.009776 (rank : 120)
Query Neighborhood Hits	133	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

RFTN1_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.015830 (rank : 101)
Query Neighborhood Hits	133	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q14699, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2	Gene names	RFTN1, KIAA0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein) (Cell migration-inducing gene 2 protein).

TARA_HUMAN
θ value	1.06291 (rank : 63)	NC score	0.017056 (rank : 98)
Query Neighborhood Hits	133	Target Neighborhood Hits	1626	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZN687_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.007320 (rank : 126)
Query Neighborhood Hits	133	Target Neighborhood Hits	1244	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

JPH2_HUMAN
θ value	1.38821 (rank : 65)	NC score	0.027471 (rank : 77)
Query Neighborhood Hits	133	Target Neighborhood Hits	639	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MTA2_HUMAN
θ value	1.38821 (rank : 66)	NC score	0.017208 (rank : 97)
Query Neighborhood Hits	133	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O94776, Q9UQB5	Gene names	MTA2, MTA1L1, PID
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex).

CASZ1_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.012811 (rank : 108)
Query Neighborhood Hits	133	Target Neighborhood Hits	473	Shared Neighborhood Hits	7
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

COIA1_HUMAN
θ value	1.81305 (rank : 68)	NC score	0.010434 (rank : 116)
Query Neighborhood Hits	133	Target Neighborhood Hits	447	Shared Neighborhood Hits	25
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GA2L2_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.014554 (rank : 105)
Query Neighborhood Hits	133	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

IRS2_MOUSE
θ value	1.81305 (rank : 70)	NC score	0.018596 (rank : 91)
Query Neighborhood Hits	133	Target Neighborhood Hits	248	Shared Neighborhood Hits	25
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MINP1_MOUSE
θ value	1.81305 (rank : 71)	NC score	0.031546 (rank : 73)
Query Neighborhood Hits	133	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2L6, Q8VDR0, Q9JJD5	Gene names	Minpp1, Mipp
Domain Architecture	No domain graphic available
Description	Multiple inositol polyphosphate phosphatase 1 precursor (EC 3.1.3.62) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase).

MUCDL_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.024950 (rank : 82)
Query Neighborhood Hits	133	Target Neighborhood Hits	777	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PHLB1_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.025998 (rank : 80)
Query Neighborhood Hits	133	Target Neighborhood Hits	678	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

EPN3_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.028792 (rank : 75)
Query Neighborhood Hits	133	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

HAIR_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.026843 (rank : 78)
Query Neighborhood Hits	133	Target Neighborhood Hits	172	Shared Neighborhood Hits	10
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

KCNN4_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.036333 (rank : 68)
Query Neighborhood Hits	133	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

NRX2A_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.024473 (rank : 83)
Query Neighborhood Hits	133	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.036038 (rank : 69)
Query Neighborhood Hits	133	Target Neighborhood Hits	481	Shared Neighborhood Hits	20
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SEPT9_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.006603 (rank : 130)
Query Neighborhood Hits	133	Target Neighborhood Hits	706	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SI1L3_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.010683 (rank : 115)
Query Neighborhood Hits	133	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

ATS13_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.002560 (rank : 139)
Query Neighborhood Hits	133	Target Neighborhood Hits	238	Shared Neighborhood Hits	2
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

DAB2_HUMAN
θ value	3.0926 (rank : 82)	NC score	0.017341 (rank : 95)
Query Neighborhood Hits	133	Target Neighborhood Hits	197	Shared Neighborhood Hits	10
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

KCNK1_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.127096 (rank : 44)
Query Neighborhood Hits	133	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNN4_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.033418 (rank : 71)
Query Neighborhood Hits	133	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

PSL1_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.026686 (rank : 79)
Query Neighborhood Hits	133	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TD49, Q3TLQ8, Q3UG60, Q80VZ6	Gene names	Sppl2b
Domain Architecture	No domain graphic available
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b).

TSC1_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.006245 (rank : 131)
Query Neighborhood Hits	133	Target Neighborhood Hits	765	Shared Neighborhood Hits	17
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

XKR7_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.017309 (rank : 96)
Query Neighborhood Hits	133	Target Neighborhood Hits	146	Shared Neighborhood Hits	10
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

AGRIN_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.002808 (rank : 138)
Query Neighborhood Hits	133	Target Neighborhood Hits	582	Shared Neighborhood Hits	13
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

BSN_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.033105 (rank : 72)
Query Neighborhood Hits	133	Target Neighborhood Hits	2057	Shared Neighborhood Hits	56
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAMKV_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.001534 (rank : 142)
Query Neighborhood Hits	133	Target Neighborhood Hits	1084	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

GRIN1_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.016352 (rank : 100)
Query Neighborhood Hits	133	Target Neighborhood Hits	337	Shared Neighborhood Hits	22
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

K1802_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.010043 (rank : 119)
Query Neighborhood Hits	133	Target Neighborhood Hits	1378	Shared Neighborhood Hits	38
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNK1_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.123411 (rank : 46)
Query Neighborhood Hits	133	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

MAP1B_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.012111 (rank : 112)
Query Neighborhood Hits	133	Target Neighborhood Hits	977	Shared Neighborhood Hits	22
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAST4_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.005123 (rank : 133)
Query Neighborhood Hits	133	Target Neighborhood Hits	1804	Shared Neighborhood Hits	49
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NIN_MOUSE
θ value	4.03905 (rank : 96)	NC score	-0.000241 (rank : 145)
Query Neighborhood Hits	133	Target Neighborhood Hits	1376	Shared Neighborhood Hits	15
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

PK2L1_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.010384 (rank : 117)
Query Neighborhood Hits	133	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

SC24C_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.028230 (rank : 76)
Query Neighborhood Hits	133	Target Neighborhood Hits	662	Shared Neighborhood Hits	32
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ADM2_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.015616 (rank : 103)
Query Neighborhood Hits	133	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNK8	Gene names	Adm2, Am2
Domain Architecture	No domain graphic available
Description	ADM2 precursor (Intermedin) [Contains: Adrenomedullin-2 (Intermedin- long) (IMDL); Intermedin-short (IMDS)].

DUS2_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.005703 (rank : 132)
Query Neighborhood Hits	133	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

K0423_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.007873 (rank : 123)
Query Neighborhood Hits	133	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

KIRR2_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.001501 (rank : 143)
Query Neighborhood Hits	133	Target Neighborhood Hits	326	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

OBSCN_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.000370 (rank : 144)
Query Neighborhood Hits	133	Target Neighborhood Hits	1931	Shared Neighborhood Hits	35
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PCLO_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.019258 (rank : 89)
Query Neighborhood Hits	133	Target Neighborhood Hits	2046	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHLB1_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.019184 (rank : 90)
Query Neighborhood Hits	133	Target Neighborhood Hits	1038	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RBNS5_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.006702 (rank : 128)
Query Neighborhood Hits	133	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

RUNX1_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.007645 (rank : 124)
Query Neighborhood Hits	133	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

TNR4_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.006700 (rank : 129)
Query Neighborhood Hits	133	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

ARHG3_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.002926 (rank : 137)
Query Neighborhood Hits	133	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

BIN1_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.016711 (rank : 99)
Query Neighborhood Hits	133	Target Neighborhood Hits	335	Shared Neighborhood Hits	15
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN1_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.015052 (rank : 104)
Query Neighborhood Hits	133	Target Neighborhood Hits	283	Shared Neighborhood Hits	16
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CAC1B_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.006896 (rank : 127)
Query Neighborhood Hits	133	Target Neighborhood Hits	351	Shared Neighborhood Hits	19
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CHD5_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.004752 (rank : 135)
Query Neighborhood Hits	133	Target Neighborhood Hits	349	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CKLF_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.023639 (rank : 84)
Query Neighborhood Hits	133	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBR5, Q9UHM7, Q9UHN8, Q9UI41	Gene names	CKLF
Domain Architecture
Description	Chemokine-like factor (C32).

CMTA2_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.012360 (rank : 109)
Query Neighborhood Hits	133	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

HD_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.010248 (rank : 118)
Query Neighborhood Hits	133	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

KCND1_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.046861 (rank : 62)
Query Neighborhood Hits	133	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNN2_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.021575 (rank : 85)
Query Neighborhood Hits	133	Target Neighborhood Hits	117	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.021552 (rank : 86)
Query Neighborhood Hits	133	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

RP1L1_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.009683 (rank : 121)
Query Neighborhood Hits	133	Target Neighborhood Hits	1072	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SLY_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.004987 (rank : 134)
Query Neighborhood Hits	133	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

TBX2_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.004541 (rank : 136)
Query Neighborhood Hits	133	Target Neighborhood Hits	195	Shared Neighborhood Hits	13
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TENS4_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.013679 (rank : 107)
Query Neighborhood Hits	133	Target Neighborhood Hits	214	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

ZN227_HUMAN
θ value	6.88961 (rank : 124)	NC score	-0.003956 (rank : 146)
Query Neighborhood Hits	133	Target Neighborhood Hits	781	Shared Neighborhood Hits	8
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

CXXC6_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.018131 (rank : 93)
Query Neighborhood Hits	133	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

FOXN1_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.018427 (rank : 92)
Query Neighborhood Hits	133	Target Neighborhood Hits	377	Shared Neighborhood Hits	18
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

HCLS1_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.001873 (rank : 140)
Query Neighborhood Hits	133	Target Neighborhood Hits	329	Shared Neighborhood Hits	8
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

LIMD1_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.008561 (rank : 122)
Query Neighborhood Hits	133	Target Neighborhood Hits	291	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MEGF9_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.011985 (rank : 113)
Query Neighborhood Hits	133	Target Neighborhood Hits	896	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

OGFR_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.029966 (rank : 74)
Query Neighborhood Hits	133	Target Neighborhood Hits	1582	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

WD21C_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.007372 (rank : 125)
Query Neighborhood Hits	133	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

ZN169_HUMAN
θ value	8.99809 (rank : 132)	NC score	-0.004128 (rank : 147)
Query Neighborhood Hits	133	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q14929, Q6PI28	Gene names	ZNF169
Domain Architecture	No domain graphic available
Description	Zinc finger protein 169.

ZO2_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.001760 (rank : 141)
Query Neighborhood Hits	133	Target Neighborhood Hits	296	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

CT152_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.061134 (rank : 58)
Query Neighborhood Hits	133	Target Neighborhood Hits	38	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KAP0_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.127812 (rank : 43)
Query Neighborhood Hits	133	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.116809 (rank : 47)
Query Neighborhood Hits	133	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.106012 (rank : 48)
Query Neighborhood Hits	133	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.103640 (rank : 49)
Query Neighborhood Hits	133	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.075471 (rank : 54)
Query Neighborhood Hits	133	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.077593 (rank : 52)
Query Neighborhood Hits	133	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.075677 (rank : 53)
Query Neighborhood Hits	133	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.078890 (rank : 51)
Query Neighborhood Hits	133	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCNK7_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.053452 (rank : 59)
Query Neighborhood Hits	133	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNK7_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.070182 (rank : 56)
Query Neighborhood Hits	133	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNKC_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.067371 (rank : 57)
Query Neighborhood Hits	133	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNKD_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.071647 (rank : 55)
Query Neighborhood Hits	133	Target Neighborhood Hits	58	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKD_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.088946 (rank : 50)
Query Neighborhood Hits	133	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

Hits sorted by NC score

KCNH3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	133	Target Neighborhood Hits	133	Shared Neighborhood Hits	133
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
NC score	0.994671 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	133	Target Neighborhood Hits	148	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH8_HUMAN
NC score	0.984758 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	53
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
NC score	0.980755 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	133	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH1_MOUSE
NC score	0.961886 (rank : 5)	θ value	4.01817e-133 (rank : 6)
Query Neighborhood Hits	133	Target Neighborhood Hits	94	Shared Neighborhood Hits	49
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.961757 (rank : 6)	θ value	8.9516e-133 (rank : 8)
Query Neighborhood Hits	133	Target Neighborhood Hits	98	Shared Neighborhood Hits	50
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH5_MOUSE
NC score	0.961543 (rank : 7)	θ value	5.24793e-133 (rank : 7)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.961425 (rank : 8)	θ value	8.9516e-133 (rank : 9)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH6_HUMAN
NC score	0.961308 (rank : 9)	θ value	5.23575e-141 (rank : 5)
Query Neighborhood Hits	133	Target Neighborhood Hits	222	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.951447 (rank : 10)	θ value	2.29227e-112 (rank : 11)
Query Neighborhood Hits	133	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.951348 (rank : 11)	θ value	1.75513e-112 (rank : 10)
Query Neighborhood Hits	133	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
NC score	0.950083 (rank : 12)	θ value	2.22025e-107 (rank : 12)
Query Neighborhood Hits	133	Target Neighborhood Hits	98	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.948987 (rank : 13)	θ value	2.71407e-105 (rank : 13)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

CNGA2_MOUSE
NC score	0.806599 (rank : 14)	θ value	8.91499e-32 (rank : 16)
Query Neighborhood Hits	133	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
NC score	0.797803 (rank : 15)	θ value	1.16434e-31 (rank : 17)
Query Neighborhood Hits	133	Target Neighborhood Hits	149	Shared Neighborhood Hits	33
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
NC score	0.797120 (rank : 16)	θ value	6.82597e-32 (rank : 15)
Query Neighborhood Hits	133	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.793841 (rank : 17)	θ value	1.37539e-32 (rank : 14)
Query Neighborhood Hits	133	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.793261 (rank : 18)	θ value	3.17079e-29 (rank : 21)
Query Neighborhood Hits	133	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN1_HUMAN
NC score	0.781208 (rank : 19)	θ value	2.42779e-29 (rank : 19)
Query Neighborhood Hits	133	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
NC score	0.777258 (rank : 20)	θ value	2.42779e-29 (rank : 20)
Query Neighborhood Hits	133	Target Neighborhood Hits	172	Shared Neighborhood Hits	34
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_MOUSE
NC score	0.775849 (rank : 21)	θ value	1.47289e-26 (rank : 25)
Query Neighborhood Hits	133	Target Neighborhood Hits	112	Shared Neighborhood Hits	38
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.775828 (rank : 22)	θ value	3.28125e-26 (rank : 26)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN2_MOUSE
NC score	0.766645 (rank : 23)	θ value	2.68423e-28 (rank : 24)
Query Neighborhood Hits	133	Target Neighborhood Hits	278	Shared Neighborhood Hits	54
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.764495 (rank : 24)	θ value	8.3442e-30 (rank : 18)
Query Neighborhood Hits	133	Target Neighborhood Hits	303	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.762826 (rank : 25)	θ value	5.40856e-29 (rank : 23)
Query Neighborhood Hits	133	Target Neighborhood Hits	284	Shared Neighborhood Hits	59
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.759634 (rank : 26)	θ value	4.14116e-29 (rank : 22)
Query Neighborhood Hits	133	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGB3_MOUSE
NC score	0.726821 (rank : 27)	θ value	5.43371e-13 (rank : 29)
Query Neighborhood Hits	133	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.715687 (rank : 28)	θ value	4.91457e-14 (rank : 28)
Query Neighborhood Hits	133	Target Neighborhood Hits	206	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.714034 (rank : 29)	θ value	1.63225e-17 (rank : 27)
Query Neighborhood Hits	133	Target Neighborhood Hits	222	Shared Neighborhood Hits	38
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
NC score	0.250350 (rank : 30)	θ value	0.00175202 (rank : 30)
Query Neighborhood Hits	133	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNKF_HUMAN
NC score	0.189924 (rank : 31)	θ value	0.0193708 (rank : 34)
Query Neighborhood Hits	133	Target Neighborhood Hits	87	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK2_HUMAN
NC score	0.183384 (rank : 32)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	133	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK3_HUMAN
NC score	0.182977 (rank : 33)	θ value	0.0113563 (rank : 33)
Query Neighborhood Hits	133	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK2_MOUSE
NC score	0.182717 (rank : 34)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	133	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_MOUSE
NC score	0.179610 (rank : 35)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	133	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.175337 (rank : 36)	θ value	0.0431538 (rank : 39)
Query Neighborhood Hits	133	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK6_HUMAN
NC score	0.172856 (rank : 37)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	133	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK4_HUMAN
NC score	0.168936 (rank : 38)	θ value	0.0431538 (rank : 38)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNKG_HUMAN
NC score	0.159805 (rank : 39)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	133	Target Neighborhood Hits	90	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK9_MOUSE
NC score	0.154050 (rank : 40)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	133	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK4_MOUSE
NC score	0.154005 (rank : 41)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	133	Target Neighborhood Hits	118	Shared Neighborhood Hits	36
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK9_HUMAN
NC score	0.153868 (rank : 42)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	133	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KAP0_HUMAN
NC score	0.127812 (rank : 43)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	133	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KCNK1_HUMAN
NC score	0.127096 (rank : 44)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	133	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK5_HUMAN
NC score	0.126564 (rank : 45)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK1_MOUSE
NC score	0.123411 (rank : 46)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	133	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KAP0_MOUSE
NC score	0.116809 (rank : 47)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	133	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.106012 (rank : 48)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	133	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
NC score	0.103640 (rank : 49)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	133	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCNKD_MOUSE
NC score	0.088946 (rank : 50)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	133	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KAP3_MOUSE
NC score	0.078890 (rank : 51)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	133	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.077593 (rank : 52)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	133	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
NC score	0.075677 (rank : 53)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	133	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_HUMAN
NC score	0.075471 (rank : 54)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	133	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KCNKD_HUMAN
NC score	0.071647 (rank : 55)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	133	Target Neighborhood Hits	58	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNK7_MOUSE
NC score	0.070182 (rank : 56)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	133	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNKC_HUMAN
NC score	0.067371 (rank : 57)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	133	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

CT152_MOUSE
NC score	0.061134 (rank : 58)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	133	Target Neighborhood Hits	38	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCNK7_HUMAN
NC score	0.053452 (rank : 59)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	133	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

PSL1_HUMAN
NC score	0.051520 (rank : 60)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	133	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

MINP1_HUMAN
NC score	0.049635 (rank : 61)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	133	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNW1, O95172, O95286, Q59EJ2, Q9UGA3	Gene names	MINPP1, MIPP
Domain Architecture	No domain graphic available
Description	Multiple inositol polyphosphate phosphatase 1 precursor (EC 3.1.3.62) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase).

KCND1_MOUSE
NC score	0.046861 (rank : 62)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	133	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KGP1B_HUMAN
NC score	0.041989 (rank : 63)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	133	Target Neighborhood Hits	921	Shared Neighborhood Hits	35
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.041923 (rank : 64)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	133	Target Neighborhood Hits	901	Shared Neighborhood Hits	35
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_MOUSE
NC score	0.041510 (rank : 65)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	133	Target Neighborhood Hits	922	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

SAPS1_HUMAN
NC score	0.038772 (rank : 66)	θ value	0.0252991 (rank : 36)
Query Neighborhood Hits	133	Target Neighborhood Hits	704	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

FA47B_HUMAN
NC score	0.038091 (rank : 67)	θ value	0.00298849 (rank : 31)
Query Neighborhood Hits	133	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

KCNN4_HUMAN
NC score	0.036333 (rank : 68)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	133	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

NRX2B_HUMAN
NC score	0.036038 (rank : 69)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	133	Target Neighborhood Hits	481	Shared Neighborhood Hits	20
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

MAGE1_HUMAN
NC score	0.035458 (rank : 70)	θ value	0.0330416 (rank : 37)
Query Neighborhood Hits	133	Target Neighborhood Hits	1389	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

KCNN4_MOUSE
NC score	0.033418 (rank : 71)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	133	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

BSN_MOUSE
NC score	0.033105 (rank : 72)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	133	Target Neighborhood Hits	2057	Shared Neighborhood Hits	56
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MINP1_MOUSE
NC score	0.031546 (rank : 73)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	133	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2L6, Q8VDR0, Q9JJD5	Gene names	Minpp1, Mipp
Domain Architecture	No domain graphic available
Description	Multiple inositol polyphosphate phosphatase 1 precursor (EC 3.1.3.62) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase).

OGFR_HUMAN
NC score	0.029966 (rank : 74)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	133	Target Neighborhood Hits	1582	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

EPN3_HUMAN
NC score	0.028792 (rank : 75)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	133	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

SC24C_HUMAN
NC score	0.028230 (rank : 76)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	133	Target Neighborhood Hits	662	Shared Neighborhood Hits	32
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

JPH2_HUMAN
NC score	0.027471 (rank : 77)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	133	Target Neighborhood Hits	639	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

HAIR_HUMAN
NC score	0.026843 (rank : 78)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	133	Target Neighborhood Hits	172	Shared Neighborhood Hits	10
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

PSL1_MOUSE
NC score	0.026686 (rank : 79)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	133	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TD49, Q3TLQ8, Q3UG60, Q80VZ6	Gene names	Sppl2b
Domain Architecture	No domain graphic available
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b).

PHLB1_MOUSE
NC score	0.025998 (rank : 80)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	133	Target Neighborhood Hits	678	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

DEPP_MOUSE
NC score	0.025240 (rank : 81)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	133	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2F3, Q8BU66	Gene names	Depp, Fseg
Domain Architecture	No domain graphic available
Description	Protein DEPP (Fat-specific expressed gene protein).

MUCDL_HUMAN
NC score	0.024950 (rank : 82)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	133	Target Neighborhood Hits	777	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NRX2A_HUMAN
NC score	0.024473 (rank : 83)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	133	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

CKLF_HUMAN
NC score	0.023639 (rank : 84)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	133	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBR5, Q9UHM7, Q9UHN8, Q9UI41	Gene names	CKLF
Domain Architecture
Description	Chemokine-like factor (C32).

KCNN2_HUMAN
NC score	0.021575 (rank : 85)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	133	Target Neighborhood Hits	117	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
NC score	0.021552 (rank : 86)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	133	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

PCLO_MOUSE
NC score	0.021544 (rank : 87)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	133	Target Neighborhood Hits	2275	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MTA2_MOUSE
NC score	0.021233 (rank : 88)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	133	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R190, Q3TVT8	Gene names	Mta2, Mta1l1
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1).

PCLO_HUMAN
NC score	0.019258 (rank : 89)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	133	Target Neighborhood Hits	2046	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHLB1_HUMAN
NC score	0.019184 (rank : 90)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	133	Target Neighborhood Hits	1038	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

IRS2_MOUSE
NC score	0.018596 (rank : 91)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	133	Target Neighborhood Hits	248	Shared Neighborhood Hits	25
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

FOXN1_HUMAN
NC score	0.018427 (rank : 92)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	133	Target Neighborhood Hits	377	Shared Neighborhood Hits	18
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

CXXC6_HUMAN
NC score	0.018131 (rank : 93)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	133	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

FBX46_MOUSE
NC score	0.017653 (rank : 94)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	133	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

DAB2_HUMAN
NC score	0.017341 (rank : 95)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	133	Target Neighborhood Hits	197	Shared Neighborhood Hits	10
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

XKR7_MOUSE
NC score	0.017309 (rank : 96)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	133	Target Neighborhood Hits	146	Shared Neighborhood Hits	10
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

MTA2_HUMAN
NC score	0.017208 (rank : 97)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	133	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O94776, Q9UQB5	Gene names	MTA2, MTA1L1, PID
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex).

TARA_HUMAN
NC score	0.017056 (rank : 98)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	133	Target Neighborhood Hits	1626	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

BIN1_HUMAN
NC score	0.016711 (rank : 99)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	133	Target Neighborhood Hits	335	Shared Neighborhood Hits	15
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

GRIN1_MOUSE
NC score	0.016352 (rank : 100)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	133	Target Neighborhood Hits	337	Shared Neighborhood Hits	22
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

RFTN1_HUMAN
NC score	0.015830 (rank : 101)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	133	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q14699, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2	Gene names	RFTN1, KIAA0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein) (Cell migration-inducing gene 2 protein).

BICD1_HUMAN
NC score	0.015786 (rank : 102)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	133	Target Neighborhood Hits	844	Shared Neighborhood Hits	11
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

ADM2_MOUSE
NC score	0.015616 (rank : 103)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	133	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNK8	Gene names	Adm2, Am2
Domain Architecture	No domain graphic available
Description	ADM2 precursor (Intermedin) [Contains: Adrenomedullin-2 (Intermedin- long) (IMDL); Intermedin-short (IMDS)].

BIN1_MOUSE
NC score	0.015052 (rank : 104)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	133	Target Neighborhood Hits	283	Shared Neighborhood Hits	16
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

GA2L2_HUMAN
NC score	0.014554 (rank : 105)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	133	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

FOXN1_MOUSE
NC score	0.013901 (rank : 106)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	133	Target Neighborhood Hits	300	Shared Neighborhood Hits	12
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

TENS4_HUMAN
NC score	0.013679 (rank : 107)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	133	Target Neighborhood Hits	214	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

CASZ1_HUMAN
NC score	0.012811 (rank : 108)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	133	Target Neighborhood Hits	473	Shared Neighborhood Hits	7
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

CMTA2_MOUSE
NC score	0.012360 (rank : 109)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	133	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

BICD1_MOUSE
NC score	0.012342 (rank : 110)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	133	Target Neighborhood Hits	837	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

DCBD1_MOUSE
NC score	0.012200 (rank : 111)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	133	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

MAP1B_MOUSE
NC score	0.012111 (rank : 112)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	133	Target Neighborhood Hits	977	Shared Neighborhood Hits	22
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MEGF9_MOUSE
NC score	0.011985 (rank : 113)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	133	Target Neighborhood Hits	896	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SEM6C_MOUSE
NC score	0.011659 (rank : 114)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	133	Target Neighborhood Hits	352	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SI1L3_HUMAN
NC score	0.010683 (rank : 115)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	133	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

COIA1_HUMAN
NC score	0.010434 (rank : 116)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	133	Target Neighborhood Hits	447	Shared Neighborhood Hits	25
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

PK2L1_HUMAN
NC score	0.010384 (rank : 117)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	133	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

HD_HUMAN
NC score	0.010248 (rank : 118)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	133	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

K1802_HUMAN
NC score	0.010043 (rank : 119)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	133	Target Neighborhood Hits	1378	Shared Neighborhood Hits	38
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MUC5B_HUMAN
NC score	0.009776 (rank : 120)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	133	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

RP1L1_HUMAN
NC score	0.009683 (rank : 121)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	133	Target Neighborhood Hits	1072	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

LIMD1_MOUSE
NC score	0.008561 (rank : 122)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	133	Target Neighborhood Hits	291	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

K0423_MOUSE
NC score	0.007873 (rank : 123)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	133	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

RUNX1_MOUSE
NC score	0.007645 (rank : 124)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	133	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

WD21C_HUMAN
NC score	0.007372 (rank : 125)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	133	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

ZN687_HUMAN
NC score	0.007320 (rank : 126)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	133	Target Neighborhood Hits	1244	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CAC1B_MOUSE
NC score	0.006896 (rank : 127)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	133	Target Neighborhood Hits	351	Shared Neighborhood Hits	19
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

RBNS5_MOUSE
NC score	0.006702 (rank : 128)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	133	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

TNR4_HUMAN
NC score	0.006700 (rank : 129)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	133	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

SEPT9_HUMAN
NC score	0.006603 (rank : 130)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	133	Target Neighborhood Hits	706	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TSC1_HUMAN
NC score	0.006245 (rank : 131)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	133	Target Neighborhood Hits	765	Shared Neighborhood Hits	17
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

DUS2_HUMAN
NC score	0.005703 (rank : 132)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	133	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

MAST4_HUMAN
NC score	0.005123 (rank : 133)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	133	Target Neighborhood Hits	1804	Shared Neighborhood Hits	49
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SLY_MOUSE
NC score	0.004987 (rank : 134)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	133	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

CHD5_HUMAN
NC score	0.004752 (rank : 135)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	133	Target Neighborhood Hits	349	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

TBX2_HUMAN
NC score	0.004541 (rank : 136)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	133	Target Neighborhood Hits	195	Shared Neighborhood Hits	13
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

ARHG3_HUMAN
NC score	0.002926 (rank : 137)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	133	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

AGRIN_HUMAN
NC score	0.002808 (rank : 138)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	133	Target Neighborhood Hits	582	Shared Neighborhood Hits	13
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ATS13_HUMAN
NC score	0.002560 (rank : 139)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	133	Target Neighborhood Hits	238	Shared Neighborhood Hits	2
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

HCLS1_MOUSE
NC score	0.001873 (rank : 140)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	133	Target Neighborhood Hits	329	Shared Neighborhood Hits	8
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

ZO2_MOUSE
NC score	0.001760 (rank : 141)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	133	Target Neighborhood Hits	296	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

CAMKV_HUMAN
NC score	0.001534 (rank : 142)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	133	Target Neighborhood Hits	1084	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

KIRR2_MOUSE
NC score	0.001501 (rank : 143)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	133	Target Neighborhood Hits	326	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

OBSCN_HUMAN
NC score	0.000370 (rank : 144)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	133	Target Neighborhood Hits	1931	Shared Neighborhood Hits	35
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

NIN_MOUSE
NC score	-0.000241 (rank : 145)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	133	Target Neighborhood Hits	1376	Shared Neighborhood Hits	15
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

ZN227_HUMAN
NC score	-0.003956 (rank : 146)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	133	Target Neighborhood Hits	781	Shared Neighborhood Hits	8
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

ZN169_HUMAN
NC score	-0.004128 (rank : 147)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	133	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q14929, Q6PI28	Gene names	ZNF169
Domain Architecture	No domain graphic available
Description	Zinc finger protein 169.