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Network neighborhood for query Sequence : RFTN1_HUMAN

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RFTN1_HUMAN
SwissProt Accessions	Q14699, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2	Gene names	RFTN1, KIAA0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein) (Cell migration-inducing gene 2 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RFTN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q14699, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2	Gene names	RFTN1, KIAA0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein) (Cell migration-inducing gene 2 protein).

RFTN1_MOUSE
θ value	0 (rank : 2)	NC score	0.974973 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q6A0D4, Q3U654, Q3U8P6, Q80US1	Gene names	Rftn1, Kiaa0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein).

RFTN2_HUMAN
θ value	1.7238e-59 (rank : 3)	NC score	0.865568 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q52LD8, Q2TA69, Q53QE0, Q53SE1, Q96NM3	Gene names	RFTN2, C2orf11
Domain Architecture	No domain graphic available
Description	Raftlin-2 (Raft-linking protein 2).

RFTN2_MOUSE
θ value	3.25095e-58 (rank : 4)	NC score	0.864999 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHX7, Q8R306, Q9CXJ5	Gene names	Rftn2
Domain Architecture	No domain graphic available
Description	Raftlin-2 (Raft-linking protein 2).

BRE1A_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.034669 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	1071	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

KI21A_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.024597 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	1543	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

LRRF1_HUMAN
θ value	0.21417 (rank : 7)	NC score	0.040814 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	625	Shared Neighborhood Hits	13
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MYT1_MOUSE
θ value	0.21417 (rank : 8)	NC score	0.031513 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	385	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

KI21A_MOUSE
θ value	0.279714 (rank : 9)	NC score	0.024203 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	1317	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

PDE6A_HUMAN
θ value	0.279714 (rank : 10)	NC score	0.020271 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P16499	Gene names	PDE6A, PDEA
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha) (PDE V-B1).

BRE1A_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.033651 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	1025	Shared Neighborhood Hits	16
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

DREB_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.046160 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	450	Shared Neighborhood Hits	8
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

ZC3H8_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.047322 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

HTSF1_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.035702 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	425	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

IF3A_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.026905 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	871	Shared Neighborhood Hits	20
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

MYLK_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.004722 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	1489	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NSBP1_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.041104 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	251	Shared Neighborhood Hits	10
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

OGFR_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.016967 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	1582	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

KCNH3_MOUSE
θ value	1.06291 (rank : 19)	NC score	0.015830 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

SRCH_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.039895 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

ANR11_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.021534 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	1289	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

UBP8_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.018729 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	751	Shared Neighborhood Hits	20
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

CS007_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.038350 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	464	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

SFR12_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.030806 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	486	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

CN145_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.016113 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	1196	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

DREB_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.039957 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	446	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

IRK6_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.013611 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	P48051, Q53WW6	Gene names	KCNJ6, GIRK2, KATP2, KCNJ7
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (BIR1).

MYPT1_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.014195 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	723	Shared Neighborhood Hits	14
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

N4BP3_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.026964 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

ANKY2_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.016776 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	306	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

CS007_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.036668 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DGKD_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.013306 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	231	Shared Neighborhood Hits	2
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

F10C1_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.028418 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q70Z53, Q70Z49, Q70Z50, Q70Z51, Q70Z52, Q8N293, Q8WVH5, Q96JQ8	Gene names	FRA10AC1, C10orf4
Domain Architecture	No domain graphic available
Description	Protein FRA10AC1.

PAR3L_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.014478 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

ANR25_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.014804 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	350	Shared Neighborhood Hits	10
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

CALX_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.014559 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CSF1_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.022891 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	258	Shared Neighborhood Hits	7
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

FOXP2_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.010155 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	366	Shared Neighborhood Hits	7
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

HORN_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.015754 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

K0195_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.020489 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

M3K3_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.001963 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	876	Shared Neighborhood Hits	4
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

NASP_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.035204 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	709	Shared Neighborhood Hits	23
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PHF3_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.023536 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

BRCA1_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.014796 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	381	Shared Neighborhood Hits	7
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

CBX2_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.014845 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CD2L5_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.002034 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	1011	Shared Neighborhood Hits	11
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CDON_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.009637 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	410	Shared Neighborhood Hits	4
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

GHRL_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.053822 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQX0, Q9WUZ1	Gene names	Ghrl, Mtlrp
Domain Architecture
Description	Appetite-regulating hormone precursor (Growth hormone secretagogue) (Growth hormone-releasing peptide) (Motilin-related peptide) (M46 protein) [Contains: Ghrelin; Obestatin].

GLU2B_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.017871 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

SFR12_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.026415 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	553	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

CENPF_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.012577 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	1932	Shared Neighborhood Hits	27
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CSTN2_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.007642 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4D0, Q9BSS0	Gene names	CLSTN2, CS2
Domain Architecture
Description	Calsyntenin-2 precursor.

NOTC2_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.003553 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	1113	Shared Neighborhood Hits	10
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OL139_MOUSE
θ value	6.88961 (rank : 54)	NC score	-0.000981 (rank : 73)
Query Neighborhood Hits	72	Target Neighborhood Hits	736	Shared Neighborhood Hits	2
SwissProt Accessions	Q60891, Q8VGR1, Q9EPY8	Gene names	Olfr139, Mor255-2, Olfr1
Domain Architecture	No domain graphic available
Description	Olfactory receptor 139 (Olfactory receptor 1) (Olfactory receptor 255- 2) (Odorant receptor M5).

RIMB1_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.015258 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	1376	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIN3_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.012811 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SMG5_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.016299 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

TAU_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.012927 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	448	Shared Neighborhood Hits	9
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

UTP20_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.014392 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q5XG71, Q80V22, Q8BXH9, Q8CHL6, Q99K11	Gene names	Utp20, Drim
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein).

ARHGC_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.006431 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	351	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BAT2_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.018451 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	931	Shared Neighborhood Hits	17
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DCMC_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.014048 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O95822, Q9UNU5, Q9Y3F2	Gene names	MLYCD
Domain Architecture
Description	Malonyl-CoA decarboxylase, mitochondrial precursor (EC 4.1.1.9) (MCD).

DMRT2_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.019088 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5R5	Gene names	DMRT2, DSXL2
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2).

DMRTA_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.015986 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CFG4	Gene names	Dmrta1, Dmrt4
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1 (Doublesex- and mab-3-related transcription factor 4).

MARCS_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.034297 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MTF1_MOUSE
θ value	8.99809 (rank : 66)	NC score	-0.000961 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	785	Shared Neighborhood Hits	3
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

PGCA_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.005625 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	643	Shared Neighborhood Hits	6
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PHX2B_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.004574 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.004574 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

RAI14_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.012374 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	1505	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SRRM1_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.012938 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	966	Shared Neighborhood Hits	18
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TNNT2_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.014392 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	395	Shared Neighborhood Hits	15
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

MRP_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.050436 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P28667, Q3TEZ4, Q91W07	Gene names	Marcksl1, Mlp, Mrp
Domain Architecture	No domain graphic available
Description	MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS) (Brain protein F52).

Hits sorted by NC score

RFTN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q14699, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2	Gene names	RFTN1, KIAA0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein) (Cell migration-inducing gene 2 protein).

RFTN1_MOUSE
NC score	0.974973 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q6A0D4, Q3U654, Q3U8P6, Q80US1	Gene names	Rftn1, Kiaa0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein).

RFTN2_HUMAN
NC score	0.865568 (rank : 3)	θ value	1.7238e-59 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q52LD8, Q2TA69, Q53QE0, Q53SE1, Q96NM3	Gene names	RFTN2, C2orf11
Domain Architecture	No domain graphic available
Description	Raftlin-2 (Raft-linking protein 2).

RFTN2_MOUSE
NC score	0.864999 (rank : 4)	θ value	3.25095e-58 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHX7, Q8R306, Q9CXJ5	Gene names	Rftn2
Domain Architecture	No domain graphic available
Description	Raftlin-2 (Raft-linking protein 2).

GHRL_MOUSE
NC score	0.053822 (rank : 5)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQX0, Q9WUZ1	Gene names	Ghrl, Mtlrp
Domain Architecture
Description	Appetite-regulating hormone precursor (Growth hormone secretagogue) (Growth hormone-releasing peptide) (Motilin-related peptide) (M46 protein) [Contains: Ghrelin; Obestatin].

MRP_MOUSE
NC score	0.050436 (rank : 6)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	72	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P28667, Q3TEZ4, Q91W07	Gene names	Marcksl1, Mlp, Mrp
Domain Architecture	No domain graphic available
Description	MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS) (Brain protein F52).

ZC3H8_MOUSE
NC score	0.047322 (rank : 7)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

DREB_HUMAN
NC score	0.046160 (rank : 8)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	450	Shared Neighborhood Hits	8
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

NSBP1_HUMAN
NC score	0.041104 (rank : 9)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	251	Shared Neighborhood Hits	10
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

LRRF1_HUMAN
NC score	0.040814 (rank : 10)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	625	Shared Neighborhood Hits	13
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

DREB_MOUSE
NC score	0.039957 (rank : 11)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	446	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

SRCH_HUMAN
NC score	0.039895 (rank : 12)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

CS007_MOUSE
NC score	0.038350 (rank : 13)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	464	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CS007_HUMAN
NC score	0.036668 (rank : 14)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

HTSF1_MOUSE
NC score	0.035702 (rank : 15)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	425	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

NASP_HUMAN
NC score	0.035204 (rank : 16)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	709	Shared Neighborhood Hits	23
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

BRE1A_HUMAN
NC score	0.034669 (rank : 17)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	1071	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

MARCS_MOUSE
NC score	0.034297 (rank : 18)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

BRE1A_MOUSE
NC score	0.033651 (rank : 19)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	1025	Shared Neighborhood Hits	16
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

MYT1_MOUSE
NC score	0.031513 (rank : 20)	θ value	0.21417 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	385	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

SFR12_MOUSE
NC score	0.030806 (rank : 21)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	486	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

F10C1_HUMAN
NC score	0.028418 (rank : 22)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q70Z53, Q70Z49, Q70Z50, Q70Z51, Q70Z52, Q8N293, Q8WVH5, Q96JQ8	Gene names	FRA10AC1, C10orf4
Domain Architecture	No domain graphic available
Description	Protein FRA10AC1.

N4BP3_HUMAN
NC score	0.026964 (rank : 23)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

IF3A_MOUSE
NC score	0.026905 (rank : 24)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	871	Shared Neighborhood Hits	20
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

SFR12_HUMAN
NC score	0.026415 (rank : 25)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	553	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

KI21A_HUMAN
NC score	0.024597 (rank : 26)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	1543	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KI21A_MOUSE
NC score	0.024203 (rank : 27)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	1317	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

PHF3_HUMAN
NC score	0.023536 (rank : 28)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

CSF1_HUMAN
NC score	0.022891 (rank : 29)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	258	Shared Neighborhood Hits	7
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

ANR11_HUMAN
NC score	0.021534 (rank : 30)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	1289	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

K0195_HUMAN
NC score	0.020489 (rank : 31)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

PDE6A_HUMAN
NC score	0.020271 (rank : 32)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P16499	Gene names	PDE6A, PDEA
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha) (PDE V-B1).

DMRT2_HUMAN
NC score	0.019088 (rank : 33)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5R5	Gene names	DMRT2, DSXL2
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2).

UBP8_HUMAN
NC score	0.018729 (rank : 34)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	751	Shared Neighborhood Hits	20
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

BAT2_HUMAN
NC score	0.018451 (rank : 35)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	931	Shared Neighborhood Hits	17
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GLU2B_MOUSE
NC score	0.017871 (rank : 36)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

OGFR_HUMAN
NC score	0.016967 (rank : 37)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	1582	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ANKY2_HUMAN
NC score	0.016776 (rank : 38)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	306	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

SMG5_HUMAN
NC score	0.016299 (rank : 39)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

CN145_HUMAN
NC score	0.016113 (rank : 40)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	1196	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

DMRTA_MOUSE
NC score	0.015986 (rank : 41)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CFG4	Gene names	Dmrta1, Dmrt4
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1 (Doublesex- and mab-3-related transcription factor 4).

KCNH3_MOUSE
NC score	0.015830 (rank : 42)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

HORN_HUMAN
NC score	0.015754 (rank : 43)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

RIMB1_MOUSE
NC score	0.015258 (rank : 44)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	1376	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CBX2_MOUSE
NC score	0.014845 (rank : 45)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

ANR25_HUMAN
NC score	0.014804 (rank : 46)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	350	Shared Neighborhood Hits	10
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

BRCA1_HUMAN
NC score	0.014796 (rank : 47)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	381	Shared Neighborhood Hits	7
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

CALX_MOUSE
NC score	0.014559 (rank : 48)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

PAR3L_HUMAN
NC score	0.014478 (rank : 49)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

UTP20_MOUSE
NC score	0.014392 (rank : 50)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q5XG71, Q80V22, Q8BXH9, Q8CHL6, Q99K11	Gene names	Utp20, Drim
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein).

TNNT2_MOUSE
NC score	0.014392 (rank : 51)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	395	Shared Neighborhood Hits	15
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

MYPT1_HUMAN
NC score	0.014195 (rank : 52)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	723	Shared Neighborhood Hits	14
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

DCMC_HUMAN
NC score	0.014048 (rank : 53)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O95822, Q9UNU5, Q9Y3F2	Gene names	MLYCD
Domain Architecture
Description	Malonyl-CoA decarboxylase, mitochondrial precursor (EC 4.1.1.9) (MCD).

IRK6_HUMAN
NC score	0.013611 (rank : 54)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	P48051, Q53WW6	Gene names	KCNJ6, GIRK2, KATP2, KCNJ7
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (BIR1).

DGKD_HUMAN
NC score	0.013306 (rank : 55)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	231	Shared Neighborhood Hits	2
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

SRRM1_MOUSE
NC score	0.012938 (rank : 56)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	966	Shared Neighborhood Hits	18
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TAU_HUMAN
NC score	0.012927 (rank : 57)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	448	Shared Neighborhood Hits	9
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

RIN3_HUMAN
NC score	0.012811 (rank : 58)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

CENPF_HUMAN
NC score	0.012577 (rank : 59)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	1932	Shared Neighborhood Hits	27
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

RAI14_MOUSE
NC score	0.012374 (rank : 60)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	1505	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

FOXP2_MOUSE
NC score	0.010155 (rank : 61)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	366	Shared Neighborhood Hits	7
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

CDON_MOUSE
NC score	0.009637 (rank : 62)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	410	Shared Neighborhood Hits	4
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CSTN2_HUMAN
NC score	0.007642 (rank : 63)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4D0, Q9BSS0	Gene names	CLSTN2, CS2
Domain Architecture
Description	Calsyntenin-2 precursor.

ARHGC_HUMAN
NC score	0.006431 (rank : 64)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	351	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PGCA_MOUSE
NC score	0.005625 (rank : 65)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	643	Shared Neighborhood Hits	6
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

MYLK_MOUSE
NC score	0.004722 (rank : 66)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	1489	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PHX2B_HUMAN
NC score	0.004574 (rank : 67)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
NC score	0.004574 (rank : 68)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

NOTC2_HUMAN
NC score	0.003553 (rank : 69)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	1113	Shared Neighborhood Hits	10
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CD2L5_MOUSE
NC score	0.002034 (rank : 70)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	1011	Shared Neighborhood Hits	11
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

M3K3_MOUSE
NC score	0.001963 (rank : 71)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	876	Shared Neighborhood Hits	4
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

MTF1_MOUSE
NC score	-0.000961 (rank : 72)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	785	Shared Neighborhood Hits	3
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

OL139_MOUSE
NC score	-0.000981 (rank : 73)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	736	Shared Neighborhood Hits	2
SwissProt Accessions	Q60891, Q8VGR1, Q9EPY8	Gene names	Olfr139, Mor255-2, Olfr1
Domain Architecture	No domain graphic available
Description	Olfactory receptor 139 (Olfactory receptor 1) (Olfactory receptor 255- 2) (Odorant receptor M5).