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Network neighborhood for query Sequence : CBX2_MOUSE

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CBX2_MOUSE
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CBX2_HUMAN
θ value	0 (rank : 1)	NC score	0.928138 (rank : 2)
Query Neighborhood Hits	119	Target Neighborhood Hits	264	Shared Neighborhood Hits	62
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	119
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX4_HUMAN
θ value	3.07116e-24 (rank : 3)	NC score	0.804034 (rank : 8)
Query Neighborhood Hits	119	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
θ value	8.93572e-24 (rank : 4)	NC score	0.801622 (rank : 9)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	34
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX7_HUMAN
θ value	1.42661e-21 (rank : 5)	NC score	0.849722 (rank : 4)
Query Neighborhood Hits	119	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX8_HUMAN
θ value	3.17815e-21 (rank : 6)	NC score	0.810413 (rank : 6)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX8_MOUSE
θ value	3.17815e-21 (rank : 7)	NC score	0.811730 (rank : 5)
Query Neighborhood Hits	119	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CBX6_HUMAN
θ value	5.42112e-21 (rank : 8)	NC score	0.798726 (rank : 10)
Query Neighborhood Hits	119	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX6_MOUSE
θ value	5.42112e-21 (rank : 9)	NC score	0.807575 (rank : 7)
Query Neighborhood Hits	119	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX7_MOUSE
θ value	1.74391e-19 (rank : 10)	NC score	0.862824 (rank : 3)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX5_MOUSE
θ value	1.2105e-12 (rank : 11)	NC score	0.675740 (rank : 11)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX5_HUMAN
θ value	1.02475e-11 (rank : 12)	NC score	0.671188 (rank : 14)
Query Neighborhood Hits	119	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX1_HUMAN
θ value	3.29651e-10 (rank : 13)	NC score	0.672389 (rank : 12)
Query Neighborhood Hits	119	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	3.29651e-10 (rank : 14)	NC score	0.672389 (rank : 13)
Query Neighborhood Hits	119	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CDYL1_HUMAN
θ value	6.87365e-08 (rank : 15)	NC score	0.413664 (rank : 17)
Query Neighborhood Hits	119	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CBX3_HUMAN
θ value	8.97725e-08 (rank : 16)	NC score	0.643400 (rank : 15)
Query Neighborhood Hits	119	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	4.45536e-07 (rank : 17)	NC score	0.631983 (rank : 16)
Query Neighborhood Hits	119	Target Neighborhood Hits	39	Shared Neighborhood Hits	32
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

MPP8_HUMAN
θ value	5.81887e-07 (rank : 18)	NC score	0.238584 (rank : 26)
Query Neighborhood Hits	119	Target Neighborhood Hits	948	Shared Neighborhood Hits	52
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CDYL2_HUMAN
θ value	8.40245e-06 (rank : 19)	NC score	0.408113 (rank : 18)
Query Neighborhood Hits	119	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

SUV91_MOUSE
θ value	1.43324e-05 (rank : 20)	NC score	0.331364 (rank : 23)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_MOUSE
θ value	2.44474e-05 (rank : 21)	NC score	0.345521 (rank : 22)
Query Neighborhood Hits	119	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

CDYL_MOUSE
θ value	5.44631e-05 (rank : 22)	NC score	0.403814 (rank : 19)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CHD1_HUMAN
θ value	5.44631e-05 (rank : 23)	NC score	0.178296 (rank : 27)
Query Neighborhood Hits	119	Target Neighborhood Hits	337	Shared Neighborhood Hits	43
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CDY1_HUMAN
θ value	0.000121331 (rank : 24)	NC score	0.383328 (rank : 21)
Query Neighborhood Hits	119	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

CDY2_HUMAN
θ value	0.000121331 (rank : 25)	NC score	0.384039 (rank : 20)
Query Neighborhood Hits	119	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CHD2_HUMAN
θ value	0.000121331 (rank : 26)	NC score	0.170225 (rank : 29)
Query Neighborhood Hits	119	Target Neighborhood Hits	360	Shared Neighborhood Hits	48
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

SUV92_HUMAN
θ value	0.000121331 (rank : 27)	NC score	0.327677 (rank : 24)
Query Neighborhood Hits	119	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

CHD1_MOUSE
θ value	0.000158464 (rank : 28)	NC score	0.176001 (rank : 28)
Query Neighborhood Hits	119	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SUV91_HUMAN
θ value	0.00298849 (rank : 29)	NC score	0.300418 (rank : 25)
Query Neighborhood Hits	119	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

CDCA7_HUMAN
θ value	0.0252991 (rank : 30)	NC score	0.086139 (rank : 33)
Query Neighborhood Hits	119	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BWT1, Q53EW5, Q580W9, Q658K4, Q658N4, Q8NBY9, Q96BV8, Q96SP5	Gene names	CDCA7, JPO1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7 (Protein JPO1).

MS3L1_MOUSE
θ value	0.0563607 (rank : 31)	NC score	0.133323 (rank : 30)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

DIDO1_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.052252 (rank : 53)
Query Neighborhood Hits	119	Target Neighborhood Hits	960	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ANKS6_MOUSE
θ value	0.21417 (rank : 33)	NC score	0.026721 (rank : 75)
Query Neighborhood Hits	119	Target Neighborhood Hits	435	Shared Neighborhood Hits	15
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

RANB3_MOUSE
θ value	0.21417 (rank : 34)	NC score	0.047370 (rank : 56)
Query Neighborhood Hits	119	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

K2027_MOUSE
θ value	0.279714 (rank : 35)	NC score	0.047088 (rank : 57)
Query Neighborhood Hits	119	Target Neighborhood Hits	106	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

TNKS1_HUMAN
θ value	0.279714 (rank : 36)	NC score	0.019387 (rank : 88)
Query Neighborhood Hits	119	Target Neighborhood Hits	477	Shared Neighborhood Hits	16
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

CIC_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.043246 (rank : 59)
Query Neighborhood Hits	119	Target Neighborhood Hits	992	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

PHF20_MOUSE
θ value	0.365318 (rank : 38)	NC score	0.044950 (rank : 58)
Query Neighborhood Hits	119	Target Neighborhood Hits	513	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

DCAK3_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.004987 (rank : 122)
Query Neighborhood Hits	119	Target Neighborhood Hits	922	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

PGCA_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.015057 (rank : 99)
Query Neighborhood Hits	119	Target Neighborhood Hits	821	Shared Neighborhood Hits	22
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

MDC1_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.039143 (rank : 61)
Query Neighborhood Hits	119	Target Neighborhood Hits	998	Shared Neighborhood Hits	36
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BSN_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.048752 (rank : 55)
Query Neighborhood Hits	119	Target Neighborhood Hits	1537	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

M3K12_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.002366 (rank : 130)
Query Neighborhood Hits	119	Target Neighborhood Hits	957	Shared Neighborhood Hits	14
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

PCLO_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.034049 (rank : 69)
Query Neighborhood Hits	119	Target Neighborhood Hits	2275	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RGS3_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.036087 (rank : 66)
Query Neighborhood Hits	119	Target Neighborhood Hits	1621	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DNL3_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.021164 (rank : 84)
Query Neighborhood Hits	119	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

FOXD2_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.007325 (rank : 116)
Query Neighborhood Hits	119	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

NFH_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.032848 (rank : 70)
Query Neighborhood Hits	119	Target Neighborhood Hits	2247	Shared Neighborhood Hits	67
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SFPQ_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.029643 (rank : 73)
Query Neighborhood Hits	119	Target Neighborhood Hits	986	Shared Neighborhood Hits	23
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

BASP_MOUSE
θ value	2.36792 (rank : 50)	NC score	0.048951 (rank : 54)
Query Neighborhood Hits	119	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAZ1A_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.022139 (rank : 83)
Query Neighborhood Hits	119	Target Neighborhood Hits	693	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CIC_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.039233 (rank : 60)
Query Neighborhood Hits	119	Target Neighborhood Hits	742	Shared Neighborhood Hits	31
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

EP400_MOUSE
θ value	2.36792 (rank : 53)	NC score	0.062894 (rank : 42)
Query Neighborhood Hits	119	Target Neighborhood Hits	592	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

IWS1_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.034472 (rank : 68)
Query Neighborhood Hits	119	Target Neighborhood Hits	1241	Shared Neighborhood Hits	43
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MATR3_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.019444 (rank : 87)
Query Neighborhood Hits	119	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MYLK_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.004400 (rank : 123)
Query Neighborhood Hits	119	Target Neighborhood Hits	1328	Shared Neighborhood Hits	16
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NCA11_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.014091 (rank : 103)
Query Neighborhood Hits	119	Target Neighborhood Hits	661	Shared Neighborhood Hits	19
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCOA6_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.037480 (rank : 63)
Query Neighborhood Hits	119	Target Neighborhood Hits	1202	Shared Neighborhood Hits	38
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

VPS72_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.036226 (rank : 65)
Query Neighborhood Hits	119	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.035643 (rank : 67)
Query Neighborhood Hits	119	Target Neighborhood Hits	286	Shared Neighborhood Hits	13
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

CAC1B_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.007697 (rank : 115)
Query Neighborhood Hits	119	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

FA44A_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.024578 (rank : 80)
Query Neighborhood Hits	119	Target Neighborhood Hits	280	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

MLL3_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.037161 (rank : 64)
Query Neighborhood Hits	119	Target Neighborhood Hits	1399	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PAF49_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.024899 (rank : 78)
Query Neighborhood Hits	119	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

PDZD2_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.023298 (rank : 82)
Query Neighborhood Hits	119	Target Neighborhood Hits	772	Shared Neighborhood Hits	29
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

POT15_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.018565 (rank : 92)
Query Neighborhood Hits	119	Target Neighborhood Hits	893	Shared Neighborhood Hits	19
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ACM1_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.002122 (rank : 131)
Query Neighborhood Hits	119	Target Neighborhood Hits	917	Shared Neighborhood Hits	4
SwissProt Accessions	P12657, Q8BJN3	Gene names	Chrm1, Chrm-1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

ANR41_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.014553 (rank : 102)
Query Neighborhood Hits	119	Target Neighborhood Hits	332	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

CD2L5_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.002858 (rank : 127)
Query Neighborhood Hits	119	Target Neighborhood Hits	1011	Shared Neighborhood Hits	20
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CNGB3_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.015295 (rank : 97)
Query Neighborhood Hits	119	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CSKP_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.004195 (rank : 125)
Query Neighborhood Hits	119	Target Neighborhood Hits	1022	Shared Neighborhood Hits	12
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.004213 (rank : 124)
Query Neighborhood Hits	119	Target Neighborhood Hits	1027	Shared Neighborhood Hits	12
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

GRIN2_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.030318 (rank : 72)
Query Neighborhood Hits	119	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

LIPA3_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.007170 (rank : 117)
Query Neighborhood Hits	119	Target Neighborhood Hits	636	Shared Neighborhood Hits	12
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

PDE1C_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.009644 (rank : 107)
Query Neighborhood Hits	119	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

RBM12_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.016885 (rank : 95)
Query Neighborhood Hits	119	Target Neighborhood Hits	313	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

ARI4A_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.057888 (rank : 46)
Query Neighborhood Hits	119	Target Neighborhood Hits	434	Shared Neighborhood Hits	21
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

DCAK3_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.003269 (rank : 126)
Query Neighborhood Hits	119	Target Neighborhood Hits	888	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

DDX31_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.009428 (rank : 108)
Query Neighborhood Hits	119	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

MYCL1_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.019807 (rank : 86)
Query Neighborhood Hits	119	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYLK_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.005556 (rank : 120)
Query Neighborhood Hits	119	Target Neighborhood Hits	1489	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NCOR2_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.017439 (rank : 93)
Query Neighborhood Hits	119	Target Neighborhood Hits	870	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NR4A1_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.005629 (rank : 119)
Query Neighborhood Hits	119	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

PCLO_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.038687 (rank : 62)
Query Neighborhood Hits	119	Target Neighborhood Hits	2046	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RFTN1_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.014845 (rank : 101)
Query Neighborhood Hits	119	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q14699, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2	Gene names	RFTN1, KIAA0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein) (Cell migration-inducing gene 2 protein).

SENP6_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.018697 (rank : 91)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SP3_HUMAN
θ value	5.27518 (rank : 87)	NC score	-0.001169 (rank : 134)
Query Neighborhood Hits	119	Target Neighborhood Hits	737	Shared Neighborhood Hits	5
SwissProt Accessions	Q02447, Q8TD56, Q9BQR1	Gene names	SP3
Domain Architecture
Description	Transcription factor Sp3 (SPR-2).

ALEX_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.024622 (rank : 79)
Query Neighborhood Hits	119	Target Neighborhood Hits	361	Shared Neighborhood Hits	16
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CABL2_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.012044 (rank : 104)
Query Neighborhood Hits	119	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

CNOT3_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.025381 (rank : 77)
Query Neighborhood Hits	119	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DLGP3_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.008937 (rank : 112)
Query Neighborhood Hits	119	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	O95886, Q5TDD5, Q9H3X7	Gene names	DLGAP3, DAP3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

FOG1_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.006570 (rank : 118)
Query Neighborhood Hits	119	Target Neighborhood Hits	1237	Shared Neighborhood Hits	35
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

KLF16_HUMAN
θ value	6.88961 (rank : 93)	NC score	-0.000026 (rank : 133)
Query Neighborhood Hits	119	Target Neighborhood Hits	737	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXK1	Gene names	KLF16, BTEB4, NSLP2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 16 (Transcription factor BTEB4) (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor NSLP2).

MAP4_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.026653 (rank : 76)
Query Neighborhood Hits	119	Target Neighborhood Hits	409	Shared Neighborhood Hits	29
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NR4A1_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.005169 (rank : 121)
Query Neighborhood Hits	119	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

PPIG_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.014900 (rank : 100)
Query Neighborhood Hits	119	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RIMB1_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.009223 (rank : 109)
Query Neighborhood Hits	119	Target Neighborhood Hits	1479	Shared Neighborhood Hits	34
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SALL3_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.001661 (rank : 132)
Query Neighborhood Hits	119	Target Neighborhood Hits	1066	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SNPC4_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.028159 (rank : 74)
Query Neighborhood Hits	119	Target Neighborhood Hits	589	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

TACC2_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.011097 (rank : 105)
Query Neighborhood Hits	119	Target Neighborhood Hits	856	Shared Neighborhood Hits	27
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TNC6B_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.018829 (rank : 89)
Query Neighborhood Hits	119	Target Neighborhood Hits	256	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

VGLL1_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.017391 (rank : 94)
Query Neighborhood Hits	119	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NC0	Gene names	Vgll1
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 1 (Vgl-1) (Vestigial- related factor).

ZN185_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.016038 (rank : 96)
Query Neighborhood Hits	119	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

AN30A_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.008488 (rank : 114)
Query Neighborhood Hits	119	Target Neighborhood Hits	1119	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ARI1B_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.024143 (rank : 81)
Query Neighborhood Hits	119	Target Neighborhood Hits	567	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ATPD_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.015129 (rank : 98)
Query Neighborhood Hits	119	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P30049	Gene names	ATP5D
Domain Architecture
Description	ATP synthase delta chain, mitochondrial precursor (EC 3.6.3.14).

CHD3_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.083503 (rank : 34)
Query Neighborhood Hits	119	Target Neighborhood Hits	397	Shared Neighborhood Hits	46
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.073018 (rank : 40)
Query Neighborhood Hits	119	Target Neighborhood Hits	365	Shared Neighborhood Hits	35
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.073635 (rank : 39)
Query Neighborhood Hits	119	Target Neighborhood Hits	408	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

DUX4_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.002654 (rank : 129)
Query Neighborhood Hits	119	Target Neighborhood Hits	403	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

H2B3A_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.008691 (rank : 113)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D2U9	Gene names	Hist3h2ba
Domain Architecture	No domain graphic available
Description	Histone H2B type 3-A.

H2B3B_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.009110 (rank : 110)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N257, Q3ZCP6, Q5TA30	Gene names	HIST3H2BB
Domain Architecture	No domain graphic available
Description	Histone H2B type 3-B (H2B type 12).

H2B3B_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.009110 (rank : 111)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGP0, Q3B7Z7	Gene names	Hist3h2bb
Domain Architecture	No domain graphic available
Description	Histone H2B type 3-B.

HSH2D_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.009897 (rank : 106)
Query Neighborhood Hits	119	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

ICAL_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.018740 (rank : 90)
Query Neighborhood Hits	119	Target Neighborhood Hits	275	Shared Neighborhood Hits	21
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

IF35_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.032540 (rank : 71)
Query Neighborhood Hits	119	Target Neighborhood Hits	210	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

KIF2C_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.002681 (rank : 128)
Query Neighborhood Hits	119	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

MAP4_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.021010 (rank : 85)
Query Neighborhood Hits	119	Target Neighborhood Hits	428	Shared Neighborhood Hits	24
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SMCA4_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.055215 (rank : 50)
Query Neighborhood Hits	119	Target Neighborhood Hits	597	Shared Neighborhood Hits	33
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

AUHM_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.060557 (rank : 44)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

AUMH_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.059820 (rank : 45)
Query Neighborhood Hits	119	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

CHD5_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.067638 (rank : 41)
Query Neighborhood Hits	119	Target Neighborhood Hits	349	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD6_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.062122 (rank : 43)
Query Neighborhood Hits	119	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.057267 (rank : 47)
Query Neighborhood Hits	119	Target Neighborhood Hits	235	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.056586 (rank : 48)
Query Neighborhood Hits	119	Target Neighborhood Hits	343	Shared Neighborhood Hits	27
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.056311 (rank : 49)
Query Neighborhood Hits	119	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

ECH1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.076089 (rank : 36)
Query Neighborhood Hits	119	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q13011, Q8WVX0, Q96EZ9	Gene names	ECH1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECH1_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.078463 (rank : 35)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O35459, Q5M8P6	Gene names	Ech1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECHM_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.074006 (rank : 38)
Query Neighborhood Hits	119	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P30084, O00739, Q5VWY1, Q96H54	Gene names	ECHS1
Domain Architecture
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

ECHM_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.074399 (rank : 37)
Query Neighborhood Hits	119	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH95, Q3TJK2, Q6GQS2, Q6PEN1, Q99LX7	Gene names	Echs1
Domain Architecture	No domain graphic available
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

EP400_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.054438 (rank : 51)
Query Neighborhood Hits	119	Target Neighborhood Hits	556	Shared Neighborhood Hits	26
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

PECI_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.113846 (rank : 31)
Query Neighborhood Hits	119	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.113121 (rank : 32)
Query Neighborhood Hits	119	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

SETD2_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.054376 (rank : 52)
Query Neighborhood Hits	119	Target Neighborhood Hits	412	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

Hits sorted by NC score

CBX2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	119
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX2_HUMAN
NC score	0.928138 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	119	Target Neighborhood Hits	264	Shared Neighborhood Hits	62
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX7_MOUSE
NC score	0.862824 (rank : 3)	θ value	1.74391e-19 (rank : 10)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_HUMAN
NC score	0.849722 (rank : 4)	θ value	1.42661e-21 (rank : 5)
Query Neighborhood Hits	119	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX8_MOUSE
NC score	0.811730 (rank : 5)	θ value	3.17815e-21 (rank : 7)
Query Neighborhood Hits	119	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CBX8_HUMAN
NC score	0.810413 (rank : 6)	θ value	3.17815e-21 (rank : 6)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX6_MOUSE
NC score	0.807575 (rank : 7)	θ value	5.42112e-21 (rank : 9)
Query Neighborhood Hits	119	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX4_HUMAN
NC score	0.804034 (rank : 8)	θ value	3.07116e-24 (rank : 3)
Query Neighborhood Hits	119	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
NC score	0.801622 (rank : 9)	θ value	8.93572e-24 (rank : 4)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	34
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX6_HUMAN
NC score	0.798726 (rank : 10)	θ value	5.42112e-21 (rank : 8)
Query Neighborhood Hits	119	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX5_MOUSE
NC score	0.675740 (rank : 11)	θ value	1.2105e-12 (rank : 11)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX1_HUMAN
NC score	0.672389 (rank : 12)	θ value	3.29651e-10 (rank : 13)
Query Neighborhood Hits	119	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.672389 (rank : 13)	θ value	3.29651e-10 (rank : 14)
Query Neighborhood Hits	119	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX5_HUMAN
NC score	0.671188 (rank : 14)	θ value	1.02475e-11 (rank : 12)
Query Neighborhood Hits	119	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX3_HUMAN
NC score	0.643400 (rank : 15)	θ value	8.97725e-08 (rank : 16)
Query Neighborhood Hits	119	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
NC score	0.631983 (rank : 16)	θ value	4.45536e-07 (rank : 17)
Query Neighborhood Hits	119	Target Neighborhood Hits	39	Shared Neighborhood Hits	32
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CDYL1_HUMAN
NC score	0.413664 (rank : 17)	θ value	6.87365e-08 (rank : 15)
Query Neighborhood Hits	119	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL2_HUMAN
NC score	0.408113 (rank : 18)	θ value	8.40245e-06 (rank : 19)
Query Neighborhood Hits	119	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

CDYL_MOUSE
NC score	0.403814 (rank : 19)	θ value	5.44631e-05 (rank : 22)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDY2_HUMAN
NC score	0.384039 (rank : 20)	θ value	0.000121331 (rank : 25)
Query Neighborhood Hits	119	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CDY1_HUMAN
NC score	0.383328 (rank : 21)	θ value	0.000121331 (rank : 24)
Query Neighborhood Hits	119	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

SUV92_MOUSE
NC score	0.345521 (rank : 22)	θ value	2.44474e-05 (rank : 21)
Query Neighborhood Hits	119	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_MOUSE
NC score	0.331364 (rank : 23)	θ value	1.43324e-05 (rank : 20)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
NC score	0.327677 (rank : 24)	θ value	0.000121331 (rank : 27)
Query Neighborhood Hits	119	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_HUMAN
NC score	0.300418 (rank : 25)	θ value	0.00298849 (rank : 29)
Query Neighborhood Hits	119	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

MPP8_HUMAN
NC score	0.238584 (rank : 26)	θ value	5.81887e-07 (rank : 18)
Query Neighborhood Hits	119	Target Neighborhood Hits	948	Shared Neighborhood Hits	52
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CHD1_HUMAN
NC score	0.178296 (rank : 27)	θ value	5.44631e-05 (rank : 23)
Query Neighborhood Hits	119	Target Neighborhood Hits	337	Shared Neighborhood Hits	43
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
NC score	0.176001 (rank : 28)	θ value	0.000158464 (rank : 28)
Query Neighborhood Hits	119	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
NC score	0.170225 (rank : 29)	θ value	0.000121331 (rank : 26)
Query Neighborhood Hits	119	Target Neighborhood Hits	360	Shared Neighborhood Hits	48
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

MS3L1_MOUSE
NC score	0.133323 (rank : 30)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

PECI_HUMAN
NC score	0.113846 (rank : 31)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	119	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
NC score	0.113121 (rank : 32)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	119	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

CDCA7_HUMAN
NC score	0.086139 (rank : 33)	θ value	0.0252991 (rank : 30)
Query Neighborhood Hits	119	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BWT1, Q53EW5, Q580W9, Q658K4, Q658N4, Q8NBY9, Q96BV8, Q96SP5	Gene names	CDCA7, JPO1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7 (Protein JPO1).

CHD3_HUMAN
NC score	0.083503 (rank : 34)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	119	Target Neighborhood Hits	397	Shared Neighborhood Hits	46
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ECH1_MOUSE
NC score	0.078463 (rank : 35)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O35459, Q5M8P6	Gene names	Ech1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECH1_HUMAN
NC score	0.076089 (rank : 36)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	119	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q13011, Q8WVX0, Q96EZ9	Gene names	ECH1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECHM_MOUSE
NC score	0.074399 (rank : 37)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	119	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH95, Q3TJK2, Q6GQS2, Q6PEN1, Q99LX7	Gene names	Echs1
Domain Architecture	No domain graphic available
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

ECHM_HUMAN
NC score	0.074006 (rank : 38)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	119	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P30084, O00739, Q5VWY1, Q96H54	Gene names	ECHS1
Domain Architecture
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

CHD4_MOUSE
NC score	0.073635 (rank : 39)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	119	Target Neighborhood Hits	408	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD4_HUMAN
NC score	0.073018 (rank : 40)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	119	Target Neighborhood Hits	365	Shared Neighborhood Hits	35
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD5_HUMAN
NC score	0.067638 (rank : 41)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	119	Target Neighborhood Hits	349	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

EP400_MOUSE
NC score	0.062894 (rank : 42)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	119	Target Neighborhood Hits	592	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

CHD6_HUMAN
NC score	0.062122 (rank : 43)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	119	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

AUHM_MOUSE
NC score	0.060557 (rank : 44)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

AUMH_HUMAN
NC score	0.059820 (rank : 45)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	119	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

ARI4A_HUMAN
NC score	0.057888 (rank : 46)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	119	Target Neighborhood Hits	434	Shared Neighborhood Hits	21
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CHD8_HUMAN
NC score	0.057267 (rank : 47)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	119	Target Neighborhood Hits	235	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_HUMAN
NC score	0.056586 (rank : 48)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	119	Target Neighborhood Hits	343	Shared Neighborhood Hits	27
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
NC score	0.056311 (rank : 49)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	119	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

SMCA4_HUMAN
NC score	0.055215 (rank : 50)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	119	Target Neighborhood Hits	597	Shared Neighborhood Hits	33
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

EP400_HUMAN
NC score	0.054438 (rank : 51)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	119	Target Neighborhood Hits	556	Shared Neighborhood Hits	26
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

SETD2_HUMAN
NC score	0.054376 (rank : 52)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	119	Target Neighborhood Hits	412	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

DIDO1_HUMAN
NC score	0.052252 (rank : 53)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	119	Target Neighborhood Hits	960	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

BASP_MOUSE
NC score	0.048951 (rank : 54)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	119	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BSN_HUMAN
NC score	0.048752 (rank : 55)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	119	Target Neighborhood Hits	1537	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RANB3_MOUSE
NC score	0.047370 (rank : 56)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	119	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

K2027_MOUSE
NC score	0.047088 (rank : 57)	θ value	0.279714 (rank : 35)
Query Neighborhood Hits	119	Target Neighborhood Hits	106	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

PHF20_MOUSE
NC score	0.044950 (rank : 58)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	119	Target Neighborhood Hits	513	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

CIC_HUMAN
NC score	0.043246 (rank : 59)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	119	Target Neighborhood Hits	992	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
NC score	0.039233 (rank : 60)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	119	Target Neighborhood Hits	742	Shared Neighborhood Hits	31
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MDC1_MOUSE
NC score	0.039143 (rank : 61)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	119	Target Neighborhood Hits	998	Shared Neighborhood Hits	36
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PCLO_HUMAN
NC score	0.038687 (rank : 62)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	119	Target Neighborhood Hits	2046	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

NCOA6_HUMAN
NC score	0.037480 (rank : 63)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	119	Target Neighborhood Hits	1202	Shared Neighborhood Hits	38
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MLL3_MOUSE
NC score	0.037161 (rank : 64)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	119	Target Neighborhood Hits	1399	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

VPS72_HUMAN
NC score	0.036226 (rank : 65)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	119	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

RGS3_MOUSE
NC score	0.036087 (rank : 66)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	119	Target Neighborhood Hits	1621	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

VPS72_MOUSE
NC score	0.035643 (rank : 67)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	119	Target Neighborhood Hits	286	Shared Neighborhood Hits	13
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

IWS1_HUMAN
NC score	0.034472 (rank : 68)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	119	Target Neighborhood Hits	1241	Shared Neighborhood Hits	43
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PCLO_MOUSE
NC score	0.034049 (rank : 69)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	119	Target Neighborhood Hits	2275	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NFH_MOUSE
NC score	0.032848 (rank : 70)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	119	Target Neighborhood Hits	2247	Shared Neighborhood Hits	67
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

IF35_MOUSE
NC score	0.032540 (rank : 71)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	119	Target Neighborhood Hits	210	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

GRIN2_HUMAN
NC score	0.030318 (rank : 72)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	119	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

SFPQ_HUMAN
NC score	0.029643 (rank : 73)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	119	Target Neighborhood Hits	986	Shared Neighborhood Hits	23
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SNPC4_HUMAN
NC score	0.028159 (rank : 74)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	119	Target Neighborhood Hits	589	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

ANKS6_MOUSE
NC score	0.026721 (rank : 75)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	119	Target Neighborhood Hits	435	Shared Neighborhood Hits	15
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

MAP4_MOUSE
NC score	0.026653 (rank : 76)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	119	Target Neighborhood Hits	409	Shared Neighborhood Hits	29
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CNOT3_MOUSE
NC score	0.025381 (rank : 77)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	119	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

PAF49_MOUSE
NC score	0.024899 (rank : 78)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	119	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

ALEX_HUMAN
NC score	0.024622 (rank : 79)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	119	Target Neighborhood Hits	361	Shared Neighborhood Hits	16
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

FA44A_HUMAN
NC score	0.024578 (rank : 80)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	119	Target Neighborhood Hits	280	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

ARI1B_HUMAN
NC score	0.024143 (rank : 81)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	119	Target Neighborhood Hits	567	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

PDZD2_HUMAN
NC score	0.023298 (rank : 82)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	119	Target Neighborhood Hits	772	Shared Neighborhood Hits	29
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

BAZ1A_HUMAN
NC score	0.022139 (rank : 83)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	119	Target Neighborhood Hits	693	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

DNL3_HUMAN
NC score	0.021164 (rank : 84)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	119	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

MAP4_HUMAN
NC score	0.021010 (rank : 85)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	119	Target Neighborhood Hits	428	Shared Neighborhood Hits	24
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MYCL1_HUMAN
NC score	0.019807 (rank : 86)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	119	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MATR3_HUMAN
NC score	0.019444 (rank : 87)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	119	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

TNKS1_HUMAN
NC score	0.019387 (rank : 88)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	119	Target Neighborhood Hits	477	Shared Neighborhood Hits	16
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNC6B_HUMAN
NC score	0.018829 (rank : 89)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	119	Target Neighborhood Hits	256	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

ICAL_HUMAN
NC score	0.018740 (rank : 90)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	119	Target Neighborhood Hits	275	Shared Neighborhood Hits	21
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

SENP6_HUMAN
NC score	0.018697 (rank : 91)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

POT15_HUMAN
NC score	0.018565 (rank : 92)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	119	Target Neighborhood Hits	893	Shared Neighborhood Hits	19
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

NCOR2_HUMAN
NC score	0.017439 (rank : 93)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	119	Target Neighborhood Hits	870	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

VGLL1_MOUSE
NC score	0.017391 (rank : 94)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	119	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NC0	Gene names	Vgll1
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 1 (Vgl-1) (Vestigial- related factor).

RBM12_MOUSE
NC score	0.016885 (rank : 95)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	119	Target Neighborhood Hits	313	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

ZN185_HUMAN
NC score	0.016038 (rank : 96)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	119	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

CNGB3_HUMAN
NC score	0.015295 (rank : 97)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	119	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

ATPD_HUMAN
NC score	0.015129 (rank : 98)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	119	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P30049	Gene names	ATP5D
Domain Architecture
Description	ATP synthase delta chain, mitochondrial precursor (EC 3.6.3.14).

PGCA_HUMAN
NC score	0.015057 (rank : 99)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	119	Target Neighborhood Hits	821	Shared Neighborhood Hits	22
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PPIG_HUMAN
NC score	0.014900 (rank : 100)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	119	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RFTN1_HUMAN
NC score	0.014845 (rank : 101)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	119	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q14699, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2	Gene names	RFTN1, KIAA0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein) (Cell migration-inducing gene 2 protein).

ANR41_HUMAN
NC score	0.014553 (rank : 102)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	119	Target Neighborhood Hits	332	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

NCA11_MOUSE
NC score	0.014091 (rank : 103)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	119	Target Neighborhood Hits	661	Shared Neighborhood Hits	19
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

CABL2_HUMAN
NC score	0.012044 (rank : 104)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	119	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

TACC2_HUMAN
NC score	0.011097 (rank : 105)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	119	Target Neighborhood Hits	856	Shared Neighborhood Hits	27
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

HSH2D_HUMAN
NC score	0.009897 (rank : 106)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	119	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

PDE1C_MOUSE
NC score	0.009644 (rank : 107)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	119	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

DDX31_HUMAN
NC score	0.009428 (rank : 108)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	119	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

RIMB1_HUMAN
NC score	0.009223 (rank : 109)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	119	Target Neighborhood Hits	1479	Shared Neighborhood Hits	34
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

H2B3B_HUMAN
NC score	0.009110 (rank : 110)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N257, Q3ZCP6, Q5TA30	Gene names	HIST3H2BB
Domain Architecture	No domain graphic available
Description	Histone H2B type 3-B (H2B type 12).

H2B3B_MOUSE
NC score	0.009110 (rank : 111)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGP0, Q3B7Z7	Gene names	Hist3h2bb
Domain Architecture	No domain graphic available
Description	Histone H2B type 3-B.

DLGP3_HUMAN
NC score	0.008937 (rank : 112)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	119	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	O95886, Q5TDD5, Q9H3X7	Gene names	DLGAP3, DAP3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

H2B3A_MOUSE
NC score	0.008691 (rank : 113)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D2U9	Gene names	Hist3h2ba
Domain Architecture	No domain graphic available
Description	Histone H2B type 3-A.

AN30A_HUMAN
NC score	0.008488 (rank : 114)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	119	Target Neighborhood Hits	1119	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CAC1B_HUMAN
NC score	0.007697 (rank : 115)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	119	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

FOXD2_HUMAN
NC score	0.007325 (rank : 116)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	119	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

LIPA3_MOUSE
NC score	0.007170 (rank : 117)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	119	Target Neighborhood Hits	636	Shared Neighborhood Hits	12
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

FOG1_MOUSE
NC score	0.006570 (rank : 118)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	119	Target Neighborhood Hits	1237	Shared Neighborhood Hits	35
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

NR4A1_HUMAN
NC score	0.005629 (rank : 119)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	119	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

MYLK_MOUSE
NC score	0.005556 (rank : 120)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	119	Target Neighborhood Hits	1489	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NR4A1_MOUSE
NC score	0.005169 (rank : 121)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	119	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

DCAK3_MOUSE
NC score	0.004987 (rank : 122)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	119	Target Neighborhood Hits	922	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

MYLK_HUMAN
NC score	0.004400 (rank : 123)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	119	Target Neighborhood Hits	1328	Shared Neighborhood Hits	16
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

CSKP_MOUSE
NC score	0.004213 (rank : 124)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	119	Target Neighborhood Hits	1027	Shared Neighborhood Hits	12
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CSKP_HUMAN
NC score	0.004195 (rank : 125)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	119	Target Neighborhood Hits	1022	Shared Neighborhood Hits	12
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

DCAK3_HUMAN
NC score	0.003269 (rank : 126)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	119	Target Neighborhood Hits	888	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

CD2L5_MOUSE
NC score	0.002858 (rank : 127)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	119	Target Neighborhood Hits	1011	Shared Neighborhood Hits	20
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

KIF2C_HUMAN
NC score	0.002681 (rank : 128)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	119	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

DUX4_HUMAN
NC score	0.002654 (rank : 129)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	119	Target Neighborhood Hits	403	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

M3K12_MOUSE
NC score	0.002366 (rank : 130)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	119	Target Neighborhood Hits	957	Shared Neighborhood Hits	14
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

ACM1_MOUSE
NC score	0.002122 (rank : 131)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	119	Target Neighborhood Hits	917	Shared Neighborhood Hits	4
SwissProt Accessions	P12657, Q8BJN3	Gene names	Chrm1, Chrm-1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

SALL3_HUMAN
NC score	0.001661 (rank : 132)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	119	Target Neighborhood Hits	1066	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

KLF16_HUMAN
NC score	-0.000026 (rank : 133)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	119	Target Neighborhood Hits	737	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXK1	Gene names	KLF16, BTEB4, NSLP2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 16 (Transcription factor BTEB4) (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor NSLP2).

SP3_HUMAN
NC score	-0.001169 (rank : 134)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	119	Target Neighborhood Hits	737	Shared Neighborhood Hits	5
SwissProt Accessions	Q02447, Q8TD56, Q9BQR1	Gene names	SP3
Domain Architecture
Description	Transcription factor Sp3 (SPR-2).