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Network neighborhood for query Sequence : CBX8_HUMAN

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CBX8_HUMAN
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CBX8_HUMAN
θ value	7.27209e-159 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX8_MOUSE
θ value	2.76981e-150 (rank : 2)	NC score	0.988832 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CBX6_HUMAN
θ value	6.17384e-33 (rank : 3)	NC score	0.880551 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	104	Shared Neighborhood Hits	33
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX6_MOUSE
θ value	6.17384e-33 (rank : 4)	NC score	0.891943 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX4_HUMAN
θ value	2.05525e-28 (rank : 5)	NC score	0.849480 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
θ value	5.97985e-28 (rank : 6)	NC score	0.847396 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX7_HUMAN
θ value	1.92365e-26 (rank : 7)	NC score	0.896305 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX2_HUMAN
θ value	3.17815e-21 (rank : 8)	NC score	0.761173 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	264	Shared Neighborhood Hits	33
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX2_MOUSE
θ value	3.17815e-21 (rank : 9)	NC score	0.810413 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX7_MOUSE
θ value	5.42112e-21 (rank : 10)	NC score	0.897411 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX5_HUMAN
θ value	2.79066e-09 (rank : 11)	NC score	0.635472 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	4.76016e-09 (rank : 12)	NC score	0.635316 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX1_HUMAN
θ value	1.53129e-07 (rank : 13)	NC score	0.634918 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	1.53129e-07 (rank : 14)	NC score	0.634918 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	6.43352e-06 (rank : 15)	NC score	0.606849 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	6.43352e-06 (rank : 16)	NC score	0.597543 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CDYL_MOUSE
θ value	4.1701e-05 (rank : 17)	NC score	0.396292 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL1_HUMAN
θ value	5.44631e-05 (rank : 18)	NC score	0.390798 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	92	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDY1_HUMAN
θ value	0.000121331 (rank : 19)	NC score	0.373202 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

CDY2_HUMAN
θ value	0.000121331 (rank : 20)	NC score	0.373975 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

SUV92_MOUSE
θ value	0.000121331 (rank : 21)	NC score	0.331742 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

CDYL2_HUMAN
θ value	0.00020696 (rank : 22)	NC score	0.388183 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

MPP8_HUMAN
θ value	0.00035302 (rank : 23)	NC score	0.216513 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	948	Shared Neighborhood Hits	39
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CHD2_HUMAN
θ value	0.000602161 (rank : 24)	NC score	0.159992 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD1_HUMAN
θ value	0.00102713 (rank : 25)	NC score	0.166485 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	337	Shared Neighborhood Hits	44
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	0.00102713 (rank : 26)	NC score	0.163363 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SUV91_MOUSE
θ value	0.00175202 (rank : 27)	NC score	0.309895 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
θ value	0.00175202 (rank : 28)	NC score	0.309653 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_HUMAN
θ value	0.00665767 (rank : 29)	NC score	0.288551 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

NPBL_MOUSE
θ value	0.00869519 (rank : 30)	NC score	0.057472 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	1041	Shared Neighborhood Hits	31
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

ATX2L_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.059935 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

GLE1_HUMAN
θ value	0.163984 (rank : 32)	NC score	0.034175 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

TARA_HUMAN
θ value	0.163984 (rank : 33)	NC score	0.033622 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	1626	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DIDO1_HUMAN
θ value	0.21417 (rank : 34)	NC score	0.047187 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	960	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SETD2_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.072643 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	412	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

RBBP6_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.038139 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	1135	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CTRO_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.001535 (rank : 77)
Query Neighborhood Hits	67	Target Neighborhood Hits	2344	Shared Neighborhood Hits	16
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ADDB_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.020928 (rank : 68)
Query Neighborhood Hits	67	Target Neighborhood Hits	574	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

SEC63_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.032260 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	586	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SMG5_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.043595 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

SNIP1_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.049544 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

STOX1_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.041541 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZVD7, Q4F8Q6, Q5I946, Q5I947, Q5I948, Q5VX38, Q5VX39, Q6ZRY3, Q96LR3, Q96LS0	Gene names	STOX1, C10orf24
Domain Architecture	No domain graphic available
Description	Storkhead-box protein 1 (Winged helix domain-containing protein).

MINK1_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.001256 (rank : 78)
Query Neighborhood Hits	67	Target Neighborhood Hits	1451	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

DDX51_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.009223 (rank : 73)
Query Neighborhood Hits	67	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

SEC63_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.029767 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	601	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SETBP_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.035004 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	305	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETBP_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.034075 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	352	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

CHD3_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.074787 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	397	Shared Neighborhood Hits	35
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

SMG5_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.036622 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

SNIP1_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.049806 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

TARA_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.028106 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	1133	Shared Neighborhood Hits	15
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

C8AP2_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.022161 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	548	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

MS3L1_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.097606 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

PHF3_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.032452 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RBM15_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.019340 (rank : 69)
Query Neighborhood Hits	67	Target Neighborhood Hits	309	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

TCAL5_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.016419 (rank : 71)
Query Neighborhood Hits	67	Target Neighborhood Hits	806	Shared Neighborhood Hits	17
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ZO2_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.008365 (rank : 75)
Query Neighborhood Hits	67	Target Neighborhood Hits	296	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DNJC8_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.022016 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	380	Shared Neighborhood Hits	10
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.022450 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

HGS_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.009218 (rank : 74)
Query Neighborhood Hits	67	Target Neighborhood Hits	589	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

MK09_MOUSE
θ value	5.27518 (rank : 61)	NC score	-0.000641 (rank : 79)
Query Neighborhood Hits	67	Target Neighborhood Hits	843	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WTU6, Q8C097, Q8VDD2, Q9WTU4, Q9WTU5	Gene names	Mapk9, Jnk2, Prkm9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2).

RGS3_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.019065 (rank : 70)
Query Neighborhood Hits	67	Target Neighborhood Hits	1621	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MS3L1_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.041123 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

NIPBL_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.044680 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	1311	Shared Neighborhood Hits	34
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RGS3_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.013052 (rank : 72)
Query Neighborhood Hits	67	Target Neighborhood Hits	1375	Shared Neighborhood Hits	17
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RIMS2_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.007763 (rank : 76)
Query Neighborhood Hits	67	Target Neighborhood Hits	376	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

YTDC1_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.028386 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	458	Shared Neighborhood Hits	18
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

AUHM_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.056786 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

AUMH_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.056107 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

CHD4_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.059923 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	365	Shared Neighborhood Hits	30
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.059969 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.055902 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	349	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD6_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.051099 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	342	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

ECH1_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.071401 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q13011, Q8WVX0, Q96EZ9	Gene names	ECH1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECH1_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.073525 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O35459, Q5M8P6	Gene names	Ech1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECHM_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.069541 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P30084, O00739, Q5VWY1, Q96H54	Gene names	ECHS1
Domain Architecture
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

ECHM_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.069944 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH95, Q3TJK2, Q6GQS2, Q6PEN1, Q99LX7	Gene names	Echs1
Domain Architecture	No domain graphic available
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

PECI_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.106922 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.106358 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

Hits sorted by NC score

CBX8_HUMAN
NC score	0.999962 (rank : 1)	θ value	7.27209e-159 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX8_MOUSE
NC score	0.988832 (rank : 2)	θ value	2.76981e-150 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CBX7_MOUSE
NC score	0.897411 (rank : 3)	θ value	5.42112e-21 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_HUMAN
NC score	0.896305 (rank : 4)	θ value	1.92365e-26 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX6_MOUSE
NC score	0.891943 (rank : 5)	θ value	6.17384e-33 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX6_HUMAN
NC score	0.880551 (rank : 6)	θ value	6.17384e-33 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	104	Shared Neighborhood Hits	33
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX4_HUMAN
NC score	0.849480 (rank : 7)	θ value	2.05525e-28 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
NC score	0.847396 (rank : 8)	θ value	5.97985e-28 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX2_MOUSE
NC score	0.810413 (rank : 9)	θ value	3.17815e-21 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX2_HUMAN
NC score	0.761173 (rank : 10)	θ value	3.17815e-21 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	264	Shared Neighborhood Hits	33
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX5_HUMAN
NC score	0.635472 (rank : 11)	θ value	2.79066e-09 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
NC score	0.635316 (rank : 12)	θ value	4.76016e-09 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX1_HUMAN
NC score	0.634918 (rank : 13)	θ value	1.53129e-07 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.634918 (rank : 14)	θ value	1.53129e-07 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
NC score	0.606849 (rank : 15)	θ value	6.43352e-06 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
NC score	0.597543 (rank : 16)	θ value	6.43352e-06 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CDYL_MOUSE
NC score	0.396292 (rank : 17)	θ value	4.1701e-05 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL1_HUMAN
NC score	0.390798 (rank : 18)	θ value	5.44631e-05 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	92	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL2_HUMAN
NC score	0.388183 (rank : 19)	θ value	0.00020696 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

CDY2_HUMAN
NC score	0.373975 (rank : 20)	θ value	0.000121331 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CDY1_HUMAN
NC score	0.373202 (rank : 21)	θ value	0.000121331 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

SUV92_MOUSE
NC score	0.331742 (rank : 22)	θ value	0.000121331 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_MOUSE
NC score	0.309895 (rank : 23)	θ value	0.00175202 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
NC score	0.309653 (rank : 24)	θ value	0.00175202 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_HUMAN
NC score	0.288551 (rank : 25)	θ value	0.00665767 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

MPP8_HUMAN
NC score	0.216513 (rank : 26)	θ value	0.00035302 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	948	Shared Neighborhood Hits	39
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CHD1_HUMAN
NC score	0.166485 (rank : 27)	θ value	0.00102713 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	337	Shared Neighborhood Hits	44
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
NC score	0.163363 (rank : 28)	θ value	0.00102713 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
NC score	0.159992 (rank : 29)	θ value	0.000602161 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

PECI_HUMAN
NC score	0.106922 (rank : 30)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	67	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
NC score	0.106358 (rank : 31)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	67	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

MS3L1_MOUSE
NC score	0.097606 (rank : 32)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

CHD3_HUMAN
NC score	0.074787 (rank : 33)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	397	Shared Neighborhood Hits	35
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ECH1_MOUSE
NC score	0.073525 (rank : 34)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	67	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O35459, Q5M8P6	Gene names	Ech1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

SETD2_HUMAN
NC score	0.072643 (rank : 35)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	412	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

ECH1_HUMAN
NC score	0.071401 (rank : 36)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	67	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q13011, Q8WVX0, Q96EZ9	Gene names	ECH1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECHM_MOUSE
NC score	0.069944 (rank : 37)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	67	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH95, Q3TJK2, Q6GQS2, Q6PEN1, Q99LX7	Gene names	Echs1
Domain Architecture	No domain graphic available
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

ECHM_HUMAN
NC score	0.069541 (rank : 38)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	67	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P30084, O00739, Q5VWY1, Q96H54	Gene names	ECHS1
Domain Architecture
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

CHD4_MOUSE
NC score	0.059969 (rank : 39)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	67	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

ATX2L_MOUSE
NC score	0.059935 (rank : 40)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CHD4_HUMAN
NC score	0.059923 (rank : 41)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	67	Target Neighborhood Hits	365	Shared Neighborhood Hits	30
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

NPBL_MOUSE
NC score	0.057472 (rank : 42)	θ value	0.00869519 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	1041	Shared Neighborhood Hits	31
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

AUHM_MOUSE
NC score	0.056786 (rank : 43)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	67	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

AUMH_HUMAN
NC score	0.056107 (rank : 44)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	67	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

CHD5_HUMAN
NC score	0.055902 (rank : 45)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	67	Target Neighborhood Hits	349	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD6_HUMAN
NC score	0.051099 (rank : 46)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	67	Target Neighborhood Hits	342	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

SNIP1_HUMAN
NC score	0.049806 (rank : 47)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

SNIP1_MOUSE
NC score	0.049544 (rank : 48)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

DIDO1_HUMAN
NC score	0.047187 (rank : 49)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	960	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

NIPBL_HUMAN
NC score	0.044680 (rank : 50)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	1311	Shared Neighborhood Hits	34
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SMG5_HUMAN
NC score	0.043595 (rank : 51)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

STOX1_HUMAN
NC score	0.041541 (rank : 52)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZVD7, Q4F8Q6, Q5I946, Q5I947, Q5I948, Q5VX38, Q5VX39, Q6ZRY3, Q96LR3, Q96LS0	Gene names	STOX1, C10orf24
Domain Architecture	No domain graphic available
Description	Storkhead-box protein 1 (Winged helix domain-containing protein).

MS3L1_HUMAN
NC score	0.041123 (rank : 53)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

RBBP6_HUMAN
NC score	0.038139 (rank : 54)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	1135	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SMG5_MOUSE
NC score	0.036622 (rank : 55)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

SETBP_HUMAN
NC score	0.035004 (rank : 56)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	305	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

GLE1_HUMAN
NC score	0.034175 (rank : 57)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

SETBP_MOUSE
NC score	0.034075 (rank : 58)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	352	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

TARA_HUMAN
NC score	0.033622 (rank : 59)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	1626	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PHF3_HUMAN
NC score	0.032452 (rank : 60)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

SEC63_HUMAN
NC score	0.032260 (rank : 61)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	586	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
NC score	0.029767 (rank : 62)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	601	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

YTDC1_HUMAN
NC score	0.028386 (rank : 63)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	458	Shared Neighborhood Hits	18
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

TARA_MOUSE
NC score	0.028106 (rank : 64)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	1133	Shared Neighborhood Hits	15
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DNJC8_MOUSE
NC score	0.022450 (rank : 65)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

C8AP2_HUMAN
NC score	0.022161 (rank : 66)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	548	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

DNJC8_HUMAN
NC score	0.022016 (rank : 67)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	380	Shared Neighborhood Hits	10
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

ADDB_MOUSE
NC score	0.020928 (rank : 68)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	574	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

RBM15_HUMAN
NC score	0.019340 (rank : 69)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	309	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

RGS3_MOUSE
NC score	0.019065 (rank : 70)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	1621	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TCAL5_HUMAN
NC score	0.016419 (rank : 71)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	806	Shared Neighborhood Hits	17
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

RGS3_HUMAN
NC score	0.013052 (rank : 72)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	1375	Shared Neighborhood Hits	17
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

DDX51_MOUSE
NC score	0.009223 (rank : 73)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

HGS_MOUSE
NC score	0.009218 (rank : 74)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	589	Shared Neighborhood Hits	10
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

ZO2_MOUSE
NC score	0.008365 (rank : 75)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	296	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

RIMS2_MOUSE
NC score	0.007763 (rank : 76)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	376	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

CTRO_MOUSE
NC score	0.001535 (rank : 77)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	2344	Shared Neighborhood Hits	16
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MINK1_MOUSE
NC score	0.001256 (rank : 78)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	1451	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MK09_MOUSE
NC score	-0.000641 (rank : 79)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	843	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WTU6, Q8C097, Q8VDD2, Q9WTU4, Q9WTU5	Gene names	Mapk9, Jnk2, Prkm9
Domain Architecture
Description	Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2).